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Katerina Otrubova

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2004-2007 Chemistry and Biochemistry University of California, San Diego and San Diego State University 
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"Katerina Otrubova"
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Shelli R. McAlpine grad student 2004-2007 University of California, San Diego and San Diego State University

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Otrubova K, Chatterjee S, Ghimire S, et al. (2019) N-Acyl pyrazoles: Effective and tunable inhibitors of serine hydrolases. Bioorganic & Medicinal Chemistry
Otrubova K, Fitzgerald AE, Mani NS. (2018) A novel entry to xanthones by an intramolecular Diels-Alder reaction involving 2-(1,2-dichlorovinyloxy) aryl dienones Tetrahedron. 74: 5715-5724
Otrubova K, Srinivasan V, Boger DL. (2014) Discovery libraries targeting the major enzyme classes: the serine hydrolases. Bioorganic & Medicinal Chemistry Letters. 24: 3807-13
Duncan KK, Otrubova K, Boger DL. (2014) α-Ketoheterocycle inhibitors of fatty acid amide hydrolase: exploration of conformational constraints in the acyl side chain. Bioorganic & Medicinal Chemistry. 22: 2763-70
Otrubova K, Cravatt BF, Boger DL. (2014) Design, synthesis, and characterization of α-ketoheterocycles that additionally target the cytosolic port Cys269 of fatty acid amide hydrolase. Journal of Medicinal Chemistry. 57: 1079-89
Barker TJ, Duncan KK, Otrubova K, et al. (2013) Potent Vinblastine C20' Ureas Displaying Additionally Improved Activity Against a Vinblastine-Resistant Cancer Cell Line. Acs Medicinal Chemistry Letters. 4
Otrubova K, Brown M, McCormick MS, et al. (2013) Rational design of fatty acid amide hydrolase inhibitors that act by covalently bonding to two active site residues. Journal of the American Chemical Society. 135: 6289-99
Otrubova K, Boger DL. (2012) α-Ketoheterocycle-based Inhibitors of Fatty Acid Amide Hydrolase (FAAH). Acs Chemical Neuroscience. 3: 340-348
Otrubova K, Ezzili C, Boger DL. (2011) The discovery and development of inhibitors of fatty acid amide hydrolase (FAAH). Bioorganic & Medicinal Chemistry Letters. 21: 4674-85
Ezzili C, Otrubova K, Boger DL. (2010) Fatty acid amide signaling molecules. Bioorganic & Medicinal Chemistry Letters. 20: 5959-68
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