| Year |
Citation |
Score |
| 2019 |
Otrubova K, Chatterjee S, Ghimire S, Cravatt BF, Boger DL. N-Acyl pyrazoles: Effective and tunable inhibitors of serine hydrolases. Bioorganic & Medicinal Chemistry. PMID 30879861 DOI: 10.1016/J.Bmc.2019.03.020 |
0.419 |
|
| 2018 |
Otrubova K, Fitzgerald AE, Mani NS. A novel entry to xanthones by an intramolecular Diels-Alder reaction involving 2-(1,2-dichlorovinyloxy) aryl dienones Tetrahedron. 74: 5715-5724. DOI: 10.1016/J.Tet.2018.08.007 |
0.321 |
|
| 2014 |
Otrubova K, Srinivasan V, Boger DL. Discovery libraries targeting the major enzyme classes: the serine hydrolases. Bioorganic & Medicinal Chemistry Letters. 24: 3807-13. PMID 25037918 DOI: 10.1016/J.Bmcl.2014.06.063 |
0.421 |
|
| 2014 |
Duncan KK, Otrubova K, Boger DL. α-Ketoheterocycle inhibitors of fatty acid amide hydrolase: exploration of conformational constraints in the acyl side chain. Bioorganic & Medicinal Chemistry. 22: 2763-70. PMID 24690529 DOI: 10.1016/J.Bmc.2014.03.013 |
0.488 |
|
| 2014 |
Otrubova K, Cravatt BF, Boger DL. Design, synthesis, and characterization of α-ketoheterocycles that additionally target the cytosolic port Cys269 of fatty acid amide hydrolase. Journal of Medicinal Chemistry. 57: 1079-89. PMID 24456116 DOI: 10.1021/Jm401820Q |
0.459 |
|
| 2013 |
Barker TJ, Duncan KK, Otrubova K, Boger DL. Potent Vinblastine C20' Ureas Displaying Additionally Improved Activity Against a Vinblastine-Resistant Cancer Cell Line. Acs Medicinal Chemistry Letters. 4. PMID 24223237 DOI: 10.1021/Ml400281W |
0.382 |
|
| 2013 |
Otrubova K, Brown M, McCormick MS, Han GW, O'Neal ST, Cravatt BF, Stevens RC, Lichtman AH, Boger DL. Rational design of fatty acid amide hydrolase inhibitors that act by covalently bonding to two active site residues. Journal of the American Chemical Society. 135: 6289-99. PMID 23581831 DOI: 10.1021/Ja4014997 |
0.371 |
|
| 2012 |
Otrubova K, Boger DL. α-Ketoheterocycle-based Inhibitors of Fatty Acid Amide Hydrolase (FAAH). Acs Chemical Neuroscience. 3: 340-348. PMID 22639704 DOI: 10.1021/Cn2001206 |
0.442 |
|
| 2011 |
Otrubova K, Ezzili C, Boger DL. The discovery and development of inhibitors of fatty acid amide hydrolase (FAAH). Bioorganic & Medicinal Chemistry Letters. 21: 4674-85. PMID 21764305 DOI: 10.1016/J.Bmcl.2011.06.096 |
0.538 |
|
| 2010 |
Ezzili C, Otrubova K, Boger DL. Fatty acid amide signaling molecules. Bioorganic & Medicinal Chemistry Letters. 20: 5959-68. PMID 20817522 DOI: 10.1016/J.Bmcl.2010.08.048 |
0.456 |
|
| 2008 |
Otrubova K, Lushington G, Vander Velde D, McGuire KL, McAlpine SR. Comprehensive study of sansalvamide A derivatives and their structure-activity relationships against drug-resistant colon cancer cell lines. Journal of Medicinal Chemistry. 51: 530-44. PMID 18186604 DOI: 10.1021/Jm070731A |
0.704 |
|
| 2007 |
Otrubova K, McGuire KL, McAlpine SR. Scaffold targeting drug-resistant colon cancers. Journal of Medicinal Chemistry. 50: 1999-2002. PMID 17411027 DOI: 10.1021/Jm070088S |
0.646 |
|
| 2007 |
Rodriguez RA, Pan PS, Pan CM, Ravula S, Lapera S, Singh EK, Styers TJ, Brown JD, Cajica J, Parry E, Otrubova K, McAlpine SR. Synthesis of second-generation sansalvamide A derivatives: novel templates as potential antitumor agents. The Journal of Organic Chemistry. 72: 1980-2002. PMID 17315929 DOI: 10.1021/Jo061830J |
0.525 |
|
| 2006 |
Styers TJ, Kekec A, Rodriguez R, Brown JD, Cajica J, Pan PS, Parry E, Carroll CL, Medina I, Corral R, Lapera S, Otrubova K, Pan CM, McGuire KL, McAlpine SR. Synthesis of Sansalvamide A derivatives and their cytotoxicity in the MSS colon cancer cell line HT-29. Bioorganic & Medicinal Chemistry. 14: 5625-31. PMID 16697205 DOI: 10.1016/J.Bmc.2006.04.031 |
0.578 |
|
| 2006 |
Otrubova K, Styers TJ, Pan PS, Rodriguez R, McGuire KL, McAlpine SR. Synthesis and novel structure-activity relationships of potent sansalvamide A derivatives. Chemical Communications (Cambridge, England). 1033-4. PMID 16491200 DOI: 10.1039/B517434A |
0.742 |
|
| Show low-probability matches. |