Junjie Chen, Ph.D.

Affiliations: 
2009- Department of Experimental Radiation Oncology The University of Texas M. D. Anderson Cancer Center, USA 
Area:
genomic stability, DNA damage responsive pathways, cancer biology
Website:
https://faculty.mdanderson.org/profiles/junjie_chen.html
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"Junjie Chen"
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Cross-listing: MPROTree

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Publications

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Ko JC, Chen JC, Huang CH, et al. (2024) Downregulation of Rad51 expression and activity potentiates the cytotoxic effect of osimertinib in human non-small cell lung cancer cells. Chemotherapy
Li S, Tang M, Xiong Y, et al. (2024) Systematic investigation of BRCA1-A, -B, and -C complexes and their functions in DNA damage response and DNA repair. Oncogene
Nie L, Wang C, Huang M, et al. (2024) DePARylation is critical for S phase progression and cell survival. Elife. 12
Zhao M, Wang T, Gleber-Netto FO, et al. (2024) Mutant p53 gains oncogenic functions through a chromosomal instability-induced cytosolic DNA response. Nature Communications. 15: 180
Zhang H, Xiong Y, Sun Y, et al. (2023) RAD54L2-mediated DNA damage avoidance pathway specifically preserves genome integrity in response to topoisomerase 2 poisons. Science Advances. 9: eadi6681
Nie L, Wang C, Liu X, et al. (2023) DePARylation is critical for S phase progression and cell survival. Biorxiv : the Preprint Server For Biology
Huang M, Yao F, Nie L, et al. (2023) FACS-based genome-wide CRISPR screens define key regulators of DNA damage signaling pathways. Molecular Cell. 83: 2810-2828.e6
Chen J, Chapski DJ, Jong J, et al. (2023) Integrative transcriptomics and cell systems analyses reveal protective pathways controlled by Igfbp-3 in anthracycline-induced cardiotoxicity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 37: e22977
Park JM, Zhang H, Nie L, et al. (2023) Genome-Wide CRISPR Screens Reveal ZATT as a Synthetic Lethal Target of TOP2-Poison Etoposide That Can Act in a TDP2-Independent Pathway. International Journal of Molecular Sciences. 24
Zhang H, Xiong Y, Su D, et al. (2022) TDP1-independent pathways in the process and repair of TOP1-induced DNA damage. Nature Communications. 13: 4240
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