Yuanyuan Chen
Affiliations: | University of Pittsburgh, Pittsburgh, PA, United States |
Area:
retinal degeneration, rhodopsin folding and signalingGoogle:
"Yuanyuan Chen"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Paul R. Carey | grad student | 2004-2010 | Case Western (Chemistry Tree) |
| Krzysztof Palczewski | post-doc | 2011-2017 | Case Western |
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Publications
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| Liu X, Feng B, Vats A, et al. (2020) Pharmacological clearance of misfolded rhodopsin for the treatment of RHO-associated retinitis pigmentosa. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology |
| Getter T, Gulati S, Zimmerman R, et al. (2019) Stereospecific modulation of dimeric rhodopsin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900443RR |
| Getter T, Suh S, Hoang T, et al. (2019) The selective estrogen receptor modulator raloxifene mitigates the effect of all-trans-retinal toxicity in photoreceptor degeneration. The Journal of Biological Chemistry |
| Feng B, Liu X, Chen Y. (2019) A Rhodopsin Transport Assay by High-Content Imaging Analysis. Journal of Visualized Experiments : Jove |
| Chen Y, Chen Y, Jastrzebska B, et al. (2018) A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration. Nature Communications. 9: 1976 |
| Chen Y, Brooks MJ, Gieser L, et al. (2016) Transcriptome Profiling of NIH3T3 Cell Lines Expressing Opsin and the P23H Opsin Mutant Identifies Candidate Drugs for the Treatment of Retinitis Pigmentosa. Pharmacological Research |
| Jastrzebska B, Chen Y, Orban T, et al. (2015) Disruption of Rhodopsin Dimerization with Synthetic Peptides Targeting an Interaction Interface. The Journal of Biological Chemistry. 290: 25728-44 |
| Chen Y, Tang H, Seibel W, et al. (2015) A High-Throughput Drug Screening Strategy for Detecting Rhodopsin P23H Mutant Rescue and Degradation. Investigative Ophthalmology & Visual Science. 56: 2553-67 |
| Chen Y, Tang H. (2015) High-throughput screening assays to identify small molecules preventing photoreceptor degeneration caused by the rhodopsin P23H mutation. Methods in Molecular Biology (Clifton, N.J.). 1271: 369-90 |
| Chen Y, Tang H, Seibel W, et al. (2014) Identification and characterization of novel inhibitors of Mammalian aspartyl aminopeptidase. Molecular Pharmacology. 86: 231-42 |