Ameya Champhekar

Affiliations: 
2015 California Institute of Technology, Pasadena, CA 
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"Ameya Champhekar"
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Pan Y, Phillips JW, Zhang BD, et al. (2023) IRIS: Discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing. Proceedings of the National Academy of Sciences of the United States of America. 120: e2221116120
Monticone G, Huang Z, Csibi F, et al. (2022) Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses. Frontiers in Immunology. 13: 987298
Grasso CS, Tsoi J, Onyshchenko M, et al. (2020) Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma. Cancer Cell
Torrejon DY, Abril-Rodriguez G, Champhekar AS, et al. (2020) Overcoming genetically-based resistance mechanisms to PD-1 blockade. Cancer Discovery
Torrejon DY, Abril-Rodriguez G, Tsoi J, et al. (2019) Overcoming genetically based resistance mechanisms to PD-1 blockade. Journal of Clinical Oncology. 37: 2584-2584
Puig-Saus C, Parisi G, Garcia-Diaz A, et al. (2018) IND-enabling studies for a clinical trial to genetically program a persistent cancer-targeted immune system. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
Cunningham CR, Champhekar A, Tullius MV, et al. (2016) Type I and Type II Interferon Coordinately Regulate Suppressive Dendritic Cell Fate and Function during Viral Persistence. Plos Pathogens. 12: e1005356
Rothenberg EV, Ungerbäck J, Champhekar A. (2016) Forging T-Lymphocyte Identity: Intersecting Networks of Transcriptional Control. Advances in Immunology. 129: 109-74
Champhekar A, Damle SS, Freedman G, et al. (2015) Regulation of early T-lineage gene expression and developmental progression by the progenitor cell transcription factor PU.1. Genes & Development. 29: 832-48
Scripture-Adams DD, Damle SS, Li L, et al. (2014) GATA-3 dose-dependent checkpoints in early T cell commitment. Journal of Immunology (Baltimore, Md. : 1950). 193: 3470-91
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