Louis Lefebvre

Medical Genetics University of British Columbia, Vancouver, Vancouver, BC, Canada 
"Louis Lefebvre"
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Michael Smith grad student UBC (Chemistry Tree)
Andras Nagy post-doc


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Meaghan J Jones grad student 2004-2010 UBC (GenetiTree)
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Haage A, Wagner K, Deng W, et al. (2020) Precise coordination of cell-ECM adhesion is essential for efficient melanoblast migration during development. Development (Cambridge, England)
Bogutz AB, Brind'Amour J, Kobayashi H, et al. (2019) Evolution of imprinting via lineage-specific insertion of retroviral promoters. Nature Communications. 10: 5674
Xu Q, Xiang Y, Wang Q, et al. (2019) SETD2 regulates the maternal epigenome, genomic imprinting and embryonic development. Nature Genetics
Haage A, Goodwin K, Whitewood A, et al. (2018) Talin Autoinhibition Regulates Cell-ECM Adhesion Dynamics and Wound Healing In Vivo. Cell Reports. 25: 2401-2416.e5
Brind'Amour J, Kobayashi H, Richard Albert J, et al. (2018) LTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation. Nature Communications. 9: 3331
Bogutz AB, Oh-McGinnis R, Jacob KJ, et al. (2018) Transcription factor ASCL2 is required for development of the glycogen trophoblast cell lineage. Plos Genetics. 14: e1007587
Branco MR, King M, Perez-Garcia V, et al. (2016) Maternal DNA Methylation Regulates Early Trophoblast Development. Developmental Cell. 36: 152-63
Kelsey AD, Yang C, Leung D, et al. (2015) Impact of flanking chromosomal sequences on localization and silencing by the human non-coding RNA XIST. Genome Biology. 16: 208
Liu S, Brind'Amour J, Karimi MM, et al. (2014) Setdb1 is required for germline development and silencing of H3K9me3-marked endogenous retroviruses in primordial germ cells. Genes & Development. 28: 2041-55
Lefebvre L. (2012) Engineering of large deletions and duplications in vivo. Methods in Molecular Biology (Clifton, N.J.). 925: 137-46
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