Alessio Caruso
Affiliations: | 2016-2021 | Chemistry | Princeton University, Princeton, NJ |
2021- | Chemistry and Chemical Biology | Harvard University, Cambridge, MA, United States |
Area:
chemistry, biochemistry, enzymology, structural biologyGoogle:
"Alessio Caruso"Mean distance: (not calculated yet)
Parents
Sign in to add mentorCatherine L. Drennan | research assistant | 2014-2015 | MIT (Chemistry Tree) |
Mohammad R. Seyedsayamdost | grad student | 2016-2021 | Princeton (Chemistry Tree) |
Daniel E. Kahne | post-doc | 2021- | Harvard (Chemistry Tree) |
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Publications
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Bushin LB, Covington BC, Clark KA, et al. (2022) Bicyclostreptins are radical SAM enzyme-modified peptides with unique cyclization motifs. Nature Chemical Biology |
Caruso A, Seyedsayamdost MR. (2021) Radical SAM Enzyme QmpB Installs Two 9-Membered Ring Sactionine Macrocycles during Biogenesis of a Ribosomal Peptide Natural Product. The Journal of Organic Chemistry |
Balo AR, Caruso A, Tao L, et al. (2021) Trapping a cross-linked lysine-tryptophan radical in the catalytic cycle of the radical SAM enzyme SuiB. Proceedings of the National Academy of Sciences of the United States of America. 118 |
Caruso A, Martinie RJ, Bushin LB, et al. (2019) Macrocyclization via an Arginine-Tyrosine Crosslink Broadens the Reaction Scope of Radical -Adenosylmethionine Enzymes. Journal of the American Chemical Society |
Bowman SEJ, Backman LRF, Bjork RE, et al. (2019) Solution structure and biochemical characterization of a spare part protein that restores activity to an oxygen-damaged glycyl radical enzyme. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry |
Caruso A, Bushin LB, Clark KA, et al. (2018) A Radical Approach to Enzymatic β-Thioether Bond Formation. Journal of the American Chemical Society |
Schramma KR, Forneris CC, Caruso A, et al. (2018) Mechanistic Investigations of Lysine-Tryptophan Cross-Link Formation Catalyzed by Streptococcal Radical S-Adenosylmethionine Enzymes. Biochemistry. 57: 461-468 |