Michael P. Hayes
Affiliations: | University of Iowa, Iowa City, IA |
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| Hayes MP, O'Brien J, Fowler CA, et al. (2021) Fragment-based nuclear magnetic resonance screen against a Regulator of G Protein Signaling identifies a binding "hot spot". Chembiochem : a European Journal of Chemical Biology |
| O’Brien J, Hayes M, Watts V, et al. (2020) Approaches to Targeting Adenylyl Cyclase 1 for Novel Pain Therapeutics The Faseb Journal. 34: 1-1 |
| Doyle TB, Muntean BS, Ejendal KF, et al. (2019) Identification of Novel Adenylyl Cyclase 5 (AC5) Signaling Networks in D and D Medium Spiny Neurons using Bimolecular Fluorescence Complementation Screening. Cells. 8 |
| Sieng M, Hayes MP, O'Brien JB, et al. (2019) High-resolution structure of RGS17 suggests a role for Ca2+ in promoting the GTPase activating protein activity by RZ subfamily members. The Journal of Biological Chemistry |
| Doyle TB, Hayes MP, Chen DH, et al. (2019) Functional characterization of AC5 gain-of-function variants: Impact on the molecular basis of ADCY5-related dyskinesia. Biochemical Pharmacology |
| Bodle CR, Schamp JH, O'Brien JB, et al. (2018) Screen Targeting Lung and Prostate Cancer Oncogene Identifies Novel Inhibitors of RGS17 and Problematic Chemical Substructures. Slas Discovery : Advancing Life Sciences R & D. 2472555217752301 |
| Hayes MP, Bodle CR, Roman DL. (2017) Evaluation of the Selectivity and Cysteine-Dependence of Inhibitors Across the Regulator of G Protein Signaling Family. Molecular Pharmacology |
| Hayes MP, Soto-Velasquez M, Fowler CA, et al. (2017) Identification of FDA-approved small molecules capable of disrupting the Calmodulin-Adenylyl Cyclase 8 interaction through direct binding to Calmodulin. Acs Chemical Neuroscience |
| Bodle CR, Mackie DI, Hayes MP, et al. (2017) Natural Products Discovered in a High-Throughput Screen Identified as Inhibitors of RGS17 and as Cytostatic and Cytotoxic Agents for Lung and Prostate Cancer Cell Lines. Journal of Natural Products |
| Bodle CR, Hayes MP, O'Brien JB, et al. (2017) "Development of bimolecular luminescence complementation assay for RGS: G protein interactions in cells." Analytical Biochemistry |