| Year |
Citation |
Score |
| 2021 |
Hayes MP, O'Brien J, Fowler CA, Yu L, Roman DL, Crawford R, Doorn JA. Fragment-based nuclear magnetic resonance screen against a Regulator of G Protein Signaling identifies a binding "hot spot". Chembiochem : a European Journal of Chemical Biology. PMID 33480159 DOI: 10.1002/cbic.202000740 |
0.785 |
|
| 2020 |
O’Brien J, Hayes M, Watts V, Roman D. Approaches to Targeting Adenylyl Cyclase 1 for Novel Pain Therapeutics The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05454 |
0.562 |
|
| 2019 |
Doyle TB, Muntean BS, Ejendal KF, Hayes MP, Soto-Velasquez M, Martemyanov KA, Dessauer CW, Hu CD, Watts VJ. Identification of Novel Adenylyl Cyclase 5 (AC5) Signaling Networks in D and D Medium Spiny Neurons using Bimolecular Fluorescence Complementation Screening. Cells. 8. PMID 31752385 DOI: 10.3390/Cells8111468 |
0.434 |
|
| 2019 |
Sieng M, Hayes MP, O'Brien JB, Fowler CA, Houtman JC, Roman DL, Lyon AM. High-resolution structure of RGS17 suggests a role for Ca2+ in promoting the GTPase activating protein activity by RZ subfamily members. The Journal of Biological Chemistry. PMID 30940727 DOI: 10.1074/Jbc.Ra118.006059 |
0.743 |
|
| 2019 |
Doyle TB, Hayes MP, Chen DH, Raskind WH, Watts VJ. Functional characterization of AC5 gain-of-function variants: Impact on the molecular basis of ADCY5-related dyskinesia. Biochemical Pharmacology. PMID 30772269 DOI: 10.1016/J.Bcp.2019.02.005 |
0.302 |
|
| 2018 |
Bodle CR, Schamp JH, O'Brien JB, Hayes MP, Wu M, Doorn JA, Roman DL. Screen Targeting Lung and Prostate Cancer Oncogene Identifies Novel Inhibitors of RGS17 and Problematic Chemical Substructures. Slas Discovery : Advancing Life Sciences R & D. 2472555217752301. PMID 29351497 DOI: 10.1177/2472555217752301 |
0.749 |
|
| 2017 |
Hayes MP, Bodle CR, Roman DL. Evaluation of the Selectivity and Cysteine-Dependence of Inhibitors Across the Regulator of G Protein Signaling Family. Molecular Pharmacology. PMID 29051318 DOI: 10.1124/mol.117.109843 |
0.761 |
|
| 2017 |
Hayes MP, Soto-Velasquez M, Fowler CA, Watts VJ, Roman DL. Identification of FDA-approved small molecules capable of disrupting the Calmodulin-Adenylyl Cyclase 8 interaction through direct binding to Calmodulin. Acs Chemical Neuroscience. PMID 28968502 DOI: 10.1021/Acschemneuro.7B00349 |
0.668 |
|
| 2017 |
Bodle CR, Mackie DI, Hayes MP, Schamp JH, Miller MR, Henry MD, Doorn JA, Houtman JCD, James MA, Roman DL. Natural Products Discovered in a High-Throughput Screen Identified as Inhibitors of RGS17 and as Cytostatic and Cytotoxic Agents for Lung and Prostate Cancer Cell Lines. Journal of Natural Products. PMID 28621943 DOI: 10.1021/acs.jnatprod.7b00112 |
0.673 |
|
| 2017 |
Bodle CR, Hayes MP, O'Brien JB, Roman DL. "Development of bimolecular luminescence complementation assay for RGS: G protein interactions in cells." Analytical Biochemistry. PMID 28115169 DOI: 10.1016/j.ab.2017.01.013 |
0.739 |
|
| 2016 |
Hayes MP, Roman DL. Regulator of G Protein Signaling 17 as a Negative Modulator of GPCR Signaling in Multiple Human Cancers. The Aaps Journal. PMID 26928451 DOI: 10.1208/s12248-016-9894-1 |
0.758 |
|
| 2015 |
Brust TF, Hayes MP, Roman DL, Burris KD, Watts VJ. Bias analyses of preclinical and clinical D2 dopamine ligands: studies with immediate and complex signaling pathways. The Journal of Pharmacology and Experimental Therapeutics. 352: 480-93. PMID 25539635 DOI: 10.1124/Jpet.114.220293 |
0.644 |
|
| 2015 |
Brust TF, Hayes MP, Roman DL, Watts VJ. New functional activity of aripiprazole revealed: Robust antagonism of D2 dopamine receptor-stimulated Gβγ signaling. Biochemical Pharmacology. 93: 85-91. PMID 25449598 DOI: 10.1016/J.Bcp.2014.10.014 |
0.634 |
|
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