Lu-Lin Jiang
Affiliations: | 2014-2020 | SBP Medical Discovery Institute |
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| van de Weijer ML, Samanta K, Sergejevs N, et al. (2024) Tapasin assembly surveillance by the RNF185/Membralin ubiquitin ligase complex regulates MHC-I surface expression. Nature Communications. 15: 8508 |
| Lee CYD, De La Rocha AJ, Inouye K, et al. (2023) BAC Transgenic Expression of Human TREM2-R47H Remodels Amyloid Plaques but Unable to Reprogram Plaque-associated Microglial Reactivity in 5xFAD Mice. Biorxiv : the Preprint Server For Biology |
| Zhao P, Xu Y, Jiang L, et al. (2022) A tetravalent TREM2 agonistic antibody reduced amyloid pathology in a mouse model of Alzheimer's disease. Science Translational Medicine. 14: eabq0095 |
| Zhao P, Xu Y, Jiang LL, et al. (2022) LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions. Molecular Neurodegeneration. 17: 44 |
| Zheng Q, Song B, Li G, et al. (2022) USP25 inhibition ameliorates Alzheimer's pathology through the regulation of APP processing and Aβ generation. The Journal of Clinical Investigation. 132 |
| Jiang L, Li X, Myers S, et al. (2021) Astroglial ER protein Membralin is an essential neuroinflammation regulator. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 17: e058566 |
| Xu P, Chang JC, Zhou X, et al. (2021) GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease. The Journal of Experimental Medicine. 218 |
| Liu T, Zhu B, Liu Y, et al. (2020) Multi-omic comparison of Alzheimer's variants in human ESC-derived microglia reveals convergence at APOE. The Journal of Experimental Medicine. 217 |
| Stupack J, Xiong XP, Jiang LL, et al. (2020) Soluble SORLA enhances neurite outgrowth and regeneration through activation of the EGF Receptor/ERK signaling axis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience |
| Zhu Q, Jiang J, Gendron TF, et al. (2020) Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72. Nature Neuroscience |