Lu-Lin Jiang - Publications

Affiliations: 
2014-2020 SBP Medical Discovery Institute 

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 van de Weijer ML, Samanta K, Sergejevs N, Jiang L, Dueñas ME, Heunis T, Huang TY, Kaufman RJ, Trost M, Sanyal S, Cowley SA, Carvalho P. Tapasin assembly surveillance by the RNF185/Membralin ubiquitin ligase complex regulates MHC-I surface expression. Nature Communications. 15: 8508. PMID 39353943 DOI: 10.1038/s41467-024-52772-x  0.577
2023 Lee CYD, De La Rocha AJ, Inouye K, Langfelder P, Daggett A, Gu X, Jiang LL, Pamonag Z, Vaca RG, Richman J, Kawaguchi R, Gao F, Xu H, Yang XW. BAC Transgenic Expression of Human TREM2-R47H Remodels Amyloid Plaques but Unable to Reprogram Plaque-associated Microglial Reactivity in 5xFAD Mice. Biorxiv : the Preprint Server For Biology. PMID 37577582 DOI: 10.1101/2023.08.03.551881  0.649
2022 Zhao P, Xu Y, Jiang L, Fan X, Li L, Li X, Arase H, Zhao Y, Cao W, Zheng H, Xu H, Tong Q, Zhang N, An Z. A tetravalent TREM2 agonistic antibody reduced amyloid pathology in a mouse model of Alzheimer's disease. Science Translational Medicine. 14: eabq0095. PMID 36070367 DOI: 10.1126/scitranslmed.abq0095  0.629
2022 Zhao P, Xu Y, Jiang LL, Fan X, Ku Z, Li L, Liu X, Deng M, Arase H, Zhu JJ, Huang TY, Zhao Y, Zhang C, Xu H, Tong Q, et al. LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions. Molecular Neurodegeneration. 17: 44. PMID 35717259 DOI: 10.1186/s13024-022-00550-y  0.738
2022 Zheng Q, Song B, Li G, Cai F, Wu M, Zhao Y, Jiang L, Guo T, Shen M, Hou H, Zhou Y, Zhao Y, Di A, Zhang L, Zeng F, et al. USP25 inhibition ameliorates Alzheimer's pathology through the regulation of APP processing and Aβ generation. The Journal of Clinical Investigation. 132. PMID 35229730 DOI: 10.1172/JCI152170  0.746
2021 Jiang L, Li X, Myers S, Huang T, Kaufman RJ. Astroglial ER protein Membralin is an essential neuroinflammation regulator. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 17: e058566. PMID 34971195 DOI: 10.1002/alz.058566  0.575
2021 Xu P, Chang JC, Zhou X, Wang W, Bamkole M, Wong E, Bettayeb K, Jiang LL, Huang T, Luo W, Xu H, Nairn AC, Flajolet M, Ip NY, Li YM, et al. GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease. The Journal of Experimental Medicine. 218. PMID 34156424 DOI: 10.1084/jem.20202446  0.758
2020 Liu T, Zhu B, Liu Y, Zhang X, Yin J, Li X, Jiang L, Hodges AP, Rosenthal SB, Zhou L, Yancey J, McQuade A, Blurton-Jones M, Tanzi RE, Huang TY, et al. Multi-omic comparison of Alzheimer's variants in human ESC-derived microglia reveals convergence at APOE. The Journal of Experimental Medicine. 217. PMID 32941599 DOI: 10.1084/Jem.20200474  0.756
2020 Stupack J, Xiong XP, Jiang LL, Zhang T, Zhou L, Campos A, Ranscht B, Mobley W, Pasquale EB, Xu H, Huang TY. Soluble SORLA enhances neurite outgrowth and regeneration through activation of the EGF Receptor/ERK signaling axis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32601248 DOI: 10.1523/Jneurosci.0723-20.2020  0.555
2020 Zhu Q, Jiang J, Gendron TF, McAlonis-Downes M, Jiang L, Taylor A, Diaz Garcia S, Ghosh Dastidar S, Rodriguez MJ, King P, Zhang Y, La Spada AR, Xu H, Petrucelli L, Ravits J, et al. Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72. Nature Neuroscience. PMID 32284607 DOI: 10.1038/S41593-020-0619-5  0.522
2019 Jiang LL, Zhu B, Zhao Y, Li X, Liu T, Pina-Crespo J, Zhou L, Xu W, Rodriguez MJ, Yu H, Cleveland DW, Ravits J, Da Cruz S, Long T, Huang TY, et al. Membralin deficiency dysregulates astrocytic glutamate homeostasis leading to ALS-like impairment. The Journal of Clinical Investigation. 130. PMID 31112137 DOI: 10.1172/Jci127695  0.695
2018 Simandi Z, Pajer K, Karolyi K, Sieler T, Jiang LL, Kolostyak Z, Sari Z, Fekecs Z, Pap A, Patsalos A, Contreras GA, Reho B, Papp Z, Guo X, Horvath A, et al. Arginine methyltransferase PRMT8 provides cellular stress tolerance in aging motoneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30054395 DOI: 10.1523/Jneurosci.3389-17.2018  0.478
2018 Lee CYD, Daggett A, Gu X, Jiang LL, Langfelder P, Li X, Wang N, Zhao Y, Park CS, Cooper Y, Ferando I, Mody I, Coppola G, Xu H, Yang XW. Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models. Neuron. 97: 1032-1048.e5. PMID 29518357 DOI: 10.1016/J.Neuron.2018.02.002  0.665
2018 Zhao Y, Wu X, Li X, Jiang LL, Gui X, Liu Y, Sun Y, Zhu B, Piña-Crespo JC, Zhang M, Zhang N, Chen X, Bu G, An Z, Huang TY, et al. TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function. Neuron. 97: 1023-1031.e7. PMID 29518356 DOI: 10.1016/J.Neuron.2018.01.031  0.786
2017 Zhao Y, Li X, Huang T, Jiang LL, Tan Z, Zhang M, Cheng IH, Wang X, Bu G, Zhang YW, Wang Q, Xu H. Intracellular trafficking of TREM2 is regulated by presenilin 1. Experimental & Molecular Medicine. 49: e405. PMID 29611543 DOI: 10.1038/Emm.2017.200  0.776
2017 Zhu B, Jiang L, Huang T, Zhao Y, Liu T, Zhong Y, Li X, Campos A, Pomeroy K, Masliah E, Zhang D, Xu H. ER-associated degradation regulates Alzheimer's amyloid pathology and memory function by modulating γ-secretase activity. Nature Communications. 8: 1472. PMID 29133892 DOI: 10.1038/S41467-017-01799-4  0.77
2017 Huang TY, Zhao Y, Jiang LL, Li X, Liu Y, Sun Y, Piña-Crespo JC, Zhu B, Masliah E, Willnow TE, Pasquale EB, Xu H. SORLA attenuates EphA4 signaling and amyloid β-induced neurodegeneration. The Journal of Experimental Medicine. PMID 29114064 DOI: 10.1084/Jem.20171413  0.794
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