David E. Clapham

Affiliations: 
Neurobiology Harvard Medical School/HHMI, Boston, MA, United States 
Area:
Ion channels and calcium signaling
Website:
http://www.fas.harvard.edu/~biophys/David_E_Clapham.htm
Google:
"David E. Clapham"
Bio:

http://neuro.med.harvard.edu/faculty/clapham.html
http://www.nytimes.com/2007/01/23/science/23conv.html?_r=0
http://clapham.tch.harvard.edu/?page_type=people

Mean distance: 13.49 (cluster 11)
 
SNBCP
Cross-listing: Chemistry Tree

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Publications

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Duan J, Li J, Chen GL, et al. (2019) Cryo-EM structure of TRPC5 at 2.8-Å resolution reveals unique and conserved structural elements essential for channel function. Science Advances. 5: eaaw7935
Duan J, Li Z, Li J, et al. (2018) Structure of the mammalian TRPM7, a magnesium channel required during embryonic development. Proceedings of the National Academy of Sciences of the United States of America
Duan J, Li J, Zeng B, et al. (2018) Structure of the mouse TRPC4 ion channel. Nature Communications. 9: 3102
Hulse RE, Li Z, Huang RK, et al. (2018) Cryo-EM structure of the polycystin 2-l1 ion channel. Elife. 7
Duan J, Li Z, Li J, et al. (2018) Structure of full-length human TRPM4. Proceedings of the National Academy of Sciences of the United States of America
Liu X, Vien T, Duan J, et al. (2018) Polycystin-2 is an essential ion channel subunit in the primary cilium of the renal collecting duct epithelium. Elife. 7
Krapivinsky G, Krapivinsky L, Renthal NE, et al. (2017) Histone phosphorylation by TRPM6's cleaved kinase attenuates adjacent arginine methylation to regulate gene expression. Proceedings of the National Academy of Sciences of the United States of America
Abiria SA, Krapivinsky G, Sah R, et al. (2017) TRPM7 senses oxidative stress to release Zn(2+) from unique intracellular vesicles. Proceedings of the National Academy of Sciences of the United States of America
Chung JJ, Miki K, Kim D, et al. (2017) CatSperζ regulates the structural continuity of sperm Ca(2+) signaling domains and is required for normal fertility. Elife. 6
Pablo JL, DeCaen PG, Clapham DE. (2016) Progress in ciliary ion channel physiology. The Journal of General Physiology
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