Rory Curtis

Elixir Pharmaceuticals, Cambridge, MA, United States 
GAP43, glia, ion channels, regeneration, neurotrophins, GAP-43
"Rory Curtis"

Email: ............ History: PhD, Biochemistry, Imperial College, London, UK;
Post-doc, Regeneron Pharmaceuticals, NY;
Lecturer, Bristol University, Bristol, UK;
Senior Scientist, Millennium Pharmaceuticals, MA;
Senior Director, Elixir Pharmaceuticals, MA;

Mean distance: 14.95 (cluster 11)
Cross-listing: Chemistry Tree

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Caneba CA, Yang L, Baddour J, et al. (2014) Nitric oxide is a positive regulator of the Warburg effect in ovarian cancer cells. Cell Death & Disease. 5: e1302
Longo KA, Govek EK, Nolan A, et al. (2012) Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity (Journal of Pharmacology and Experimental Therapeutics (2011) 339, (115-124)) Journal of Pharmacology and Experimental Therapeutics. 340: 810
Longo KA, Govek EK, Nolan A, et al. (2011) Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity. The Journal of Pharmacology and Experimental Therapeutics. 339: 115-24
Medina-Gomez G, Gray SL, Yetukuri L, et al. (2007) PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism. Plos Genetics. 3: e64
DiStefano PS, Curtis R, Geddes BJ. (2007) Insulin resistance, glycemic control and adiposity: key determinants of healthy lifespan. Current Alzheimer Research. 4: 153-7
Curtis R, O'Connor G, DiStefano PS. (2006) Aging networks in Caenorhabditis elegans: AMP-activated protein kinase (aak-2) links multiple aging and metabolism pathways. Aging Cell. 5: 119-26
Solomon JM, Pasupuleti R, Xu L, et al. (2006) Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. Molecular and Cellular Biology. 26: 28-38
Napper AD, Hixon J, McDonagh T, et al. (2005) Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. Journal of Medicinal Chemistry. 48: 8045-54
McDonagh T, Hixon J, DiStefano PS, et al. (2005) Microplate filtration assay for nicotinamide release from NAD using a boronic acid resin. Methods (San Diego, Calif.). 36: 346-50
Lelliott CJ, López M, Curtis RK, et al. (2005) Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1108-19
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