Jen Q. Pan, Ph. D.
Affiliations: | Broad Institute of Harvard and MIT |
Area:
translational, schizophrenia, ion channelsGoogle:
"Jen Pan"Mean distance: 15.33 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentorDiane Lipscombe | grad student | 1996-2001 | Broad Institute of Harvard and MIT |
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Publications
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Pablo JLB, Cornett SL, Wang LA, et al. (2024) Scanning mutagenesis of the voltage-gated sodium channel Na1.2 using base editing. Cell Reports. 43: 114327 |
Pablo JLB, Cornett SL, Wang LA, et al. (2023) Scanning mutagenesis of the voltage-gated sodium channel Na1.2 using base editing. Cell Reports. 42: 112563 |
Zhang YL, Moran SP, Allen A, et al. (2022) Novel Fluorescence-Based High-Throughput FLIPR Assay Utilizing Membrane-Tethered Genetic Calcium Sensors to Identify T-Type Calcium Channel Modulators. Acs Pharmacology & Translational Science. 5: 156-168 |
Baez-Nieto D, Allen A, Akers-Campbell S, et al. (2021) Analysing an allelic series of rare missense variants of CACNA1I in a Swedish schizophrenia cohort. Brain : a Journal of Neurology |
Feseha S, Timic Stamenic T, Wallace D, et al. (2020) Global genetic deletion of Ca3.3 channels facilitates anaesthetic induction and enhances isoflurane-sparing effects of T-type calcium channel blockers. Scientific Reports. 10: 21510 |
Hwang H, Szucs MJ, Ding LJ, et al. (2020) Neurogranin, Encoded by the Schizophrenia Risk Gene NRGN, Bidirectionally Modulates Synaptic Plasticity via Calmodulin-Dependent Regulation of the Neuronal Phosphoproteome. Biological Psychiatry |
Heyne HO, Baez-Nieto D, Iqbal S, et al. (2020) Predicting functional effects of missense variants in voltage-gated sodium and calcium channels. Science Translational Medicine. 12 |
Ghoshal A, Uygun DS, Yang L, et al. (2020) Effects of a patient-derived de novo coding alteration of CACNA1I in mice connect a schizophrenia risk gene with sleep spindle deficits. Translational Psychiatry. 10: 29 |
Pan JQ, Baez-Nieto D, Allen A, et al. (2018) Developing High-Throughput Assays to Analyze and Screen Electrophysiological Phenotypes. Methods in Molecular Biology (Clifton, N.J.). 1787: 235-252 |
Andrade A, Hope J, Allen A, et al. (2016) A rare schizophrenia risk variant of CACNA1I disrupts CaV3.3 channel activity. Scientific Reports. 6: 34233 |