Jen Q. Pan, Ph. D. - Publications

Affiliations: 
Broad Institute of Harvard and MIT 
Area:
translational, schizophrenia, ion channels

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Pablo JLB, Cornett SL, Wang LA, Jo S, Brünger T, Budnik N, Hegde M, DeKeyser JM, Thompson CH, Doench JG, Lal D, George AL, Pan JQ. Scanning mutagenesis of the voltage-gated sodium channel Na1.2 using base editing. Cell Reports. 43: 114327. PMID 38823014 DOI: 10.1016/j.celrep.2024.114327  0.35
2023 Pablo JLB, Cornett SL, Wang LA, Jo S, Brünger T, Budnik N, Hegde M, DeKeyser JM, Thompson CH, Doench JG, Lal D, George AL, Pan JQ. Scanning mutagenesis of the voltage-gated sodium channel Na1.2 using base editing. Cell Reports. 42: 112563. PMID 37267104 DOI: 10.1016/j.celrep.2023.112563  0.373
2022 Zhang YL, Moran SP, Allen A, Baez-Nieto D, Xu Q, Wang LA, Martenis WE, Sacher JR, Gale JP, Weïwer M, Wagner FF, Pan JQ. Novel Fluorescence-Based High-Throughput FLIPR Assay Utilizing Membrane-Tethered Genetic Calcium Sensors to Identify T-Type Calcium Channel Modulators. Acs Pharmacology & Translational Science. 5: 156-168. PMID 35311021 DOI: 10.1021/acsptsci.1c00233  0.379
2021 Baez-Nieto D, Allen A, Akers-Campbell S, Yang L, Budnik N, Pupo A, Shin YC, Genovese G, Liao M, Pérez-Palma E, Heyne H, Lal D, Lipscombe D, Pan JQ. Analysing an allelic series of rare missense variants of CACNA1I in a Swedish schizophrenia cohort. Brain : a Journal of Neurology. PMID 34919654 DOI: 10.1093/brain/awab443  0.624
2020 Feseha S, Timic Stamenic T, Wallace D, Tamag C, Yang L, Pan JQ, Todorovic SM. Global genetic deletion of Ca3.3 channels facilitates anaesthetic induction and enhances isoflurane-sparing effects of T-type calcium channel blockers. Scientific Reports. 10: 21510. PMID 33299036 DOI: 10.1038/s41598-020-78488-8  0.369
2020 Hwang H, Szucs MJ, Ding LJ, Allen A, Ren X, Haensgen H, Gao F, Rhim H, Andrade A, Pan JQ, Carr SA, Ahmad R, Xu W. Neurogranin, Encoded by the Schizophrenia Risk Gene NRGN, Bidirectionally Modulates Synaptic Plasticity via Calmodulin-Dependent Regulation of the Neuronal Phosphoproteome. Biological Psychiatry. PMID 33032807 DOI: 10.1016/j.biopsych.2020.07.014  0.472
2020 Heyne HO, Baez-Nieto D, Iqbal S, Palmer DS, Brunklaus A, May P, Johannesen KM, Lauxmann S, Lemke JR, Møller RS, Pérez-Palma E, Scholl UI, Syrbe S, Lerche H, ... ... Pan J, et al. Predicting functional effects of missense variants in voltage-gated sodium and calcium channels. Science Translational Medicine. 12. PMID 32801145 DOI: 10.1126/Scitranslmed.Aay6848  0.357
2020 Ghoshal A, Uygun DS, Yang L, McNally JM, Lopez-Huerta VG, Arias-Garcia MA, Baez-Nieto D, Allen A, Fitzgerald M, Choi S, Zhang Q, Hope JM, Yan K, Mao X, Nicholson TB, ... ... Pan JQ, et al. Effects of a patient-derived de novo coding alteration of CACNA1I in mice connect a schizophrenia risk gene with sleep spindle deficits. Translational Psychiatry. 10: 29. PMID 32066662 DOI: 10.1038/S41398-020-0685-1  0.3
2018 Pan JQ, Baez-Nieto D, Allen A, Wang HR, Cottrell JR. Developing High-Throughput Assays to Analyze and Screen Electrophysiological Phenotypes. Methods in Molecular Biology (Clifton, N.J.). 1787: 235-252. PMID 29736723 DOI: 10.1007/978-1-4939-7847-2_18  0.339
2016 Andrade A, Hope J, Allen A, Yorgan V, Lipscombe D, Pan JQ. A rare schizophrenia risk variant of CACNA1I disrupts CaV3.3 channel activity. Scientific Reports. 6: 34233. PMID 27756899 DOI: 10.1038/srep34233  0.651
2015 Lipscombe D, Pan JQ, Schorge S. Tracks through the Genome to Physiological Events. Experimental Physiology. PMID 26053180 DOI: 10.1113/EP085129  0.569
2012 Su SC, Seo J, Pan JQ, Samuels BA, Rudenko A, Ericsson M, Neve RL, Yue DT, Tsai LH. Regulation of N-type voltage-gated calcium channels and presynaptic function by cyclin-dependent kinase 5. Neuron. 75: 675-87. PMID 22920258 DOI: 10.1016/j.neuron.2012.06.023  0.332
2009 Lipscombe D, Pan JQ. Tripping the HCN breaker. Neuron. 62: 747-50. PMID 19555642 DOI: 10.1016/j.neuron.2009.06.003  0.603
2006 Yang B, Gribkoff VK, Pan J, Damagnez V, Dworetzky SI, Boissard CG, Bhattacharjee A, Yan Y, Sigworth FJ, Kaczmarek LK. Pharmacological activation and inhibition of Slack (Slo2.2) channels. Neuropharmacology. 51: 896-906. PMID 16876206 DOI: 10.1016/J.Neuropharm.2006.06.003  0.413
2005 Winquist RJ, Pan JQ, Gribkoff VK. Use-dependent blockade of Cav2.2 voltage-gated calcium channels for neuropathic pain. Biochemical Pharmacology. 70: 489-99. PMID 15950195 DOI: 10.1016/j.bcp.2005.04.035  0.367
2002 Lipscombe D, Pan JQ, Gray AC. Functional diversity in neuronal voltage-gated calcium channels by alternative splicing of Ca(v)alpha1. Molecular Neurobiology. 26: 21-44. PMID 12392054 DOI: 10.1385/MN:26:1:021  0.664
2000 Pan JQ, Lipscombe D. Alternative splicing in the cytoplasmic II-III loop of the N-type Ca channel alpha 1B subunit: functional differences are beta subunit-specific. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 4769-75. PMID 10864934  0.626
2000 Pan JQ, Lipscombe D. Alternative Splicing in the Cytoplasmic II–III Loop of the N-Type Ca Channel α1BSubunit: Functional Differences Are β Subunit-Specific The Journal of Neuroscience. 20: 4769-4775. DOI: 10.1523/JNEUROSCI.20-13-04769.2000  0.67
1999 Lin Z, Lin Y, Schorge S, Pan JQ, Beierlein M, Lipscombe D. Alternative splicing of a short cassette exon in alpha1B generates functionally distinct N-type calcium channels in central and peripheral neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 5322-31. PMID 10377343 DOI: 10.1523/Jneurosci.19-13-05322.1999  0.664
Show low-probability matches.