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Yongjin Yoo, Ph.D.

Affiliations: 
2013-2018 Biomedical Science Seoual National University 
 2018-2024 Institute for Stem Cell Biology and Regenerative Medicine Stanford University, Palo Alto, CA 
 2024- Department of Neuroscience, College of Medicine Korea University, Seoul, South Korea 
Area:
Neural stem cells, Microglia, Reprogramming
Website:
https://www.yongjinyoolab.com
Google:
"https://scholar.google.com/citations?user=QSvHyfoAAAAJ&hl=en"
Bio:

Yongjin earned his B.S. from Shanghai Jiao Tong University, majoring in Biotechnology. As an undergraduate researcher in the Wu Geng laboratory, he studied X-ray protein crystallography for the SUFU protein, one of the most conserved components of the Hedgehog signaling pathway.
Under the guidance of Dr. Murim Choi, he earned his Ph.D. in Biomedical Science from Seoul National University. His research during his graduate studies focused on neurodevelopmental disorders, where he utilized whole-exome sequencing to identify novel genetic mutations in Rett syndrome-like patients and investigated their pathophysiology using cell and animal models.
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Parents

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Murim Choi grad student 2013-2018 Seoul National Univerity
Marius Wernig post-doc 2018-2024 Stanford (Cell Biology Tree)

Children

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Publications

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Mader MM, Napole A, Wu D, et al. (2024) Myeloid cell replacement is neuroprotective in chronic experimental autoimmune encephalomyelitis. Nature Neuroscience
Susanto TT, Hung V, Levine AG, et al. (2023) RAPIDASH: A tag-free enrichment of ribosome-associated proteins reveals compositional dynamics in embryonic tissues and stimulated macrophages. Biorxiv : the Preprint Server For Biology
Guo MG, Reynolds DL, Ang CE, et al. (2023) Integrative analyses highlight functional regulatory variants associated with neuropsychiatric diseases. Nature Genetics
Yoo Y, Neumayer G, Shibuya Y, et al. (2023) A cell therapy approach to restore microglial Trem2 function in a mouse model of Alzheimer's disease. Cell Stem Cell. 30: 1392
Yoo Y, Neumayer G, Shibuya Y, et al. (2023) A cell therapy approach to restore microglial Trem2 function in a mouse model of Alzheimer's disease. Cell Stem Cell. 30: 1043-1053.e6
Mader MM, Napole A, Wu D, et al. (2023) Augmentation of a neuroprotective myeloid state by hematopoietic cell transplantation. Biorxiv : the Preprint Server For Biology
Shibuya Y, Kumar KK, Mader MM, et al. (2022) Treatment of a genetic brain disease by CNS-wide microglia replacement. Science Translational Medicine. 14: eabl9945
Yoo Y, Park SY, Jo EB, et al. (2021) Overexpression of Replication-Dependent Histone Signifies a Subset of Dedifferentiated Liposarcoma with Increased Aggressiveness. Cancers. 13
Lee Y, Park S, Lee JS, et al. (2020) Genomic profiling of 553 uncharacterized neurodevelopment patients reveals a high proportion of recessive pathogenic variant carriers in an outbred population. Scientific Reports. 10: 1413
Salpietro V, Dixon CL, Guo H, et al. (2019) AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders. Nature Communications. 10: 3094
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