Stephane A Laporte
Affiliations: | McGill University, Montreal, QC, Canada |
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Publications
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Sarma P, Carino CMC, Seetharama D, et al. (2023) Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system. Nature Communications. 14: 4808 |
Cao Y, van der Velden WJC, Namkung Y, et al. (2023) Unraveling allostery within the angiotensin II type 1 receptor for Gα and β-arrestin coupling. Science Signaling. 16: eadf2173 |
Sandhu M, Cho A, Ma N, et al. (2022) Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity. Nature Communications. 13: 7428 |
Baidya M, Chaturvedi M, Dwivedi-Agnihotri H, et al. (2022) Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody. Nature Communications. 13: 4634 |
Sedki D, Cho A, Cao Y, et al. (2022) Prostaglandin F2α and angiotensin II type 1 receptors exhibit differential cognate G protein coupling regulation. The Journal of Biological Chemistry. 102294 |
Pandey S, Kumari P, Baidya M, et al. (2021) Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors. Molecular Cell |
Free RB, Cuoco CA, Xie B, et al. (2021) Pharmacological characterization of the imipridone anti-cancer drug ONC201 reveals a negative allosteric mechanism of action at the D dopamine receptor. Molecular Pharmacology |
Giubilaro J, Schuetz DA, Stepniewski TM, et al. (2021) Discovery of a dual Ras and ARF6 inhibitor from a GPCR endocytosis screen. Nature Communications. 12: 4688 |
Baidya M, Kumari P, Dwivedi-Agnihotri H, et al. (2020) Key phosphorylation sites in GPCRs orchestrate the contribution of β-Arrestin 1 in ERK1/2 activation. Embo Reports. e49886 |
Cao Y, Kumar S, Namkung Y, et al. (2020) Angiotensin II type 1 receptor variants alter endosomal receptor-β-arrestin complex stability and MAPK activation. The Journal of Biological Chemistry |