Laura Dearden

Affiliations: 
University of Cambridge, Cambridge, England, United Kingdom 
Area:
developmental programming hypothalamus
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Dearden L, Furigo IC, Pantaleão LC, et al. (2024) Maternal obesity increases hypothalamic miR-505-5p expression in mouse offspring leading to altered fatty acid sensing and increased intake of high-fat food. Plos Biology. 22: e3002641
Dearden L, Ozanne SE. (2023) Early life impacts of maternal obesity: a window of opportunity to improve the health of two generations. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 378: 20220222
Furigo IC, Dearden L. (2022) Mechanisms mediating the impact of maternal obesity on offspring hypothalamic development and later function. Frontiers in Endocrinology. 13: 1078955
Schoonejans JM, Blackmore HL, Ashmore TJ, et al. (2022) Sex-specific effects of maternal metformin intervention during glucose-intolerant obese pregnancy on body composition and metabolic health in aged mouse offspring. Diabetologia. 65: 2132-2145
Hufnagel A, Dearden L, Fernandez-Twinn DS, et al. (2022) Programming of cardiometabolic health: the role of maternal and fetal hyperinsulinaemia. The Journal of Endocrinology. 253: R47-R63
Dearden L, Bouret SG, Ozanne SE. (2021) Nutritional and developmental programming effects of insulin. Journal of Neuroendocrinology. e12933
Beeson JH, Blackmore HL, Carr SK, et al. (2018) Maternal exercise intervention in obese pregnancy improves the cardiovascular health of the adult male offspring. Molecular Metabolism. 16: 35-44
Berends LM, Dearden L, Tung YCL, et al. (2018) Programming of central and peripheral insulin resistance by low birthweight and postnatal catch-up growth in male mice. Diabetologia
Dearden L, Bouret SG, Ozanne SE. (2018) Sex and gender differences in developmental programming of metabolism. Molecular Metabolism
Aiken CE, Tarry-Adkins JL, Penfold NC, et al. (2015) Decreased ovarian reserve, dysregulation of mitochondrial biogenesis, and increased lipid peroxidation in female mouse offspring exposed to an obesogenic maternal diet. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 30: 1548-56
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