Curtis Terrence Keith

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2000 Harvard University, Cambridge, MA, United States 
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"Curtis Keith"
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Stuart L. Schreiber grad student 2000 Harvard
 (Biochemical and genomic approaches to PIK -related kinases.)
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Lee MS, Johansen L, Zhang Y, et al. (2007) The novel combination of chlorpromazine and pentamidine exerts synergistic antiproliferative effects through dual mitotic action. Cancer Research. 67: 11359-67
Lehár J, Zimmermann GR, Krueger AS, et al. (2007) Chemical combination effects predict connectivity in biological systems. Molecular Systems Biology. 3: 80
Zimmermann GR, Lehár J, Keith CT. (2007) Multi-target therapeutics: when the whole is greater than the sum of the parts. Drug Discovery Today. 12: 34-42
Keith CT, Borisy AA, Stockwell BR. (2005) Multicomponent therapeutics for networked systems. Nature Reviews. Drug Discovery. 4: 71-8
Borisy AA, Elliott PJ, Hurst NW, et al. (2003) Systematic discovery of multicomponent therapeutics. Proceedings of the National Academy of Sciences of the United States of America. 100: 7977-82
Cimprich KA, Shin TB, Keith CT, et al. (1996) cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein. Proceedings of the National Academy of Sciences of the United States of America. 93: 2850-5
Keith CT, Schreiber SL. (1995) PIK-related kinases: DNA repair, recombination, and cell cycle checkpoints. Science (New York, N.Y.). 270: 50-1
Brown EJ, Beal PA, Keith CT, et al. (1995) Control of p70 s6 kinase by kinase activity of FRAP in vivo. Nature. 377: 441-6
Brown EJ, Beal PA, Keith CT, et al. (1995) Erratum: Control of p70 S6 kinase by kinase activity of FRAP in vivo Nature. 378: 644-644
Brown EJ, Albers MW, Shin TB, et al. (1994) A mammalian protein targeted by G1-arresting rapamycin-receptor complex. Nature. 369: 756-8
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