Michael F. Egan - Publications

Affiliations: 
Associate Director, Neuroscience, Merck & Co., Inc. ;UG4D-34; P.O. Box 1000 
Area:
genetics, schizophrenia, pharmacology

141 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Ursini G, Punzi G, Chen Q, Marenco S, Robinson JF, Porcelli A, Hamilton EG, Mitjans M, Maddalena G, Begemann M, Seidel J, Yanamori H, Jaffe AE, Berman KF, Egan MF, et al. Convergence of placenta biology and genetic risk for schizophrenia. Nature Medicine. PMID 29808008 DOI: 10.1038/s41591-018-0021-y  1
2014 Weickert TW, Terrazas A, Bigelow LB, Apud JA, Egan MF, Weinberger DR. Perceptual Category Judgment Deficits are Related to Prefrontal Decision Making Abnormalities in Schizophrenia. Frontiers in Psychiatry. 4: 184. PMID 24432006 DOI: 10.3389/fpsyt.2013.00184  1
2013 Weickert TW, Mattay VS, Das S, Bigelow LB, Apud JA, Egan MF, Weinberger DR, Goldberg TE. Dopaminergic therapy removal differentially effects learning in schizophrenia and Parkinson's disease. Schizophrenia Research. 149: 162-6. PMID 23830543 DOI: 10.1016/j.schres.2013.06.028  1
2012 Hornig M, Briese T, Licinio J, Khabbaz RF, Altshuler LL, Potkin SG, Schwemmle M, Siemetzki U, Mintz J, Honkavuori K, Kraemer HC, Egan MF, Whybrow PC, Bunney WE, Lipkin WI. Absence of evidence for bornavirus infection in schizophrenia, bipolar disorder and major depressive disorder. Molecular Psychiatry. 17: 486-93. PMID 22290118 DOI: 10.1038/mp.2011.179  1
2012 Kopald BE, Mirra KM, Egan MF, Weinberger DR, Goldberg TE. Magnitude of impact of executive functioning and IQ on episodic memory in Schizophrenia. Biological Psychiatry. 71: 545-51. PMID 22265665 DOI: 10.1016/j.biopsych.2011.11.021  1
2011 Egan MF, Cannon TD. Intermediate Phenotypes in Genetic Studies of Schizophrenia Schizophrenia: Third Edition. 289-310. DOI: 10.1002/9781444327298.ch14  1
2010 Weickert TW, Goldberg TE, Egan MF, Apud JA, Meeter M, Myers CE, Gluck MA, Weinberger DR. Relative risk of probabilistic category learning deficits in patients with schizophrenia and their siblings. Biological Psychiatry. 67: 948-55. PMID 20172502 DOI: 10.1016/j.biopsych.2009.12.027  1
2009 Huffaker SJ, Chen J, Nicodemus KK, Sambataro F, Yang F, Mattay V, Lipska BK, Hyde TM, Song J, Rujescu D, Giegling I, Mayilyan K, Proust MJ, Soghoyan A, Caforio G, ... ... Egan MF, et al. A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia. Nature Medicine. 15: 509-18. PMID 19412172 DOI: 10.1038/nm.1962  1
2009 Shapiro DI, Marenco S, Spoor EH, Egan MF, Weinberger DR, Gold JM. The Premorbid Adjustment Scale as a measure of developmental compromise in patients with schizophrenia and their healthy siblings. Schizophrenia Research. 112: 136-42. PMID 19410430 DOI: 10.1016/j.schres.2009.04.007  1
2009 Weickert TW, Goldberg TE, Callicott JH, Chen Q, Apud JA, Das S, Zoltick BJ, Egan MF, Meeter M, Myers C, Gluck MA, Weinberger DR, Mattay VS. Neural correlates of probabilistic category learning in patients with schizophrenia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1244-54. PMID 19176832 DOI: 10.1523/JNEUROSCI.4341-08.2009  1
2008 Kempf L, Nicodemus KK, Kolachana B, Vakkalanka R, Verchinski BA, Egan MF, Straub RE, Mattay VA, Callicott JH, Weinberger DR, Meyer-Lindenberg A. Functional polymorphisms in PRODH are associated with risk and protection for schizophrenia and fronto-striatal structure and function. Plos Genetics. 4: e1000252. PMID 18989458 DOI: 10.1371/journal.pgen.1000252  1
2008 Hyde TM, Deep-Soboslay A, Iglesias B, Callicott JH, Gold JM, Meyer-Lindenberg A, Honea RA, Bigelow LB, Egan MF, Emsellem EM, Weinberger DR. Enuresis as a premorbid developmental marker of schizophrenia. Brain : a Journal of Neurology. 131: 2489-98. PMID 18669483 DOI: 10.1093/brain/awn167  1
2008 Skelley SL, Goldberg TE, Egan MF, Weinberger DR, Gold JM. Verbal and visual memory: characterizing the clinical and intermediate phenotype in schizophrenia. Schizophrenia Research. 105: 78-85. PMID 18617370 DOI: 10.1016/j.schres.2008.05.027  1
2008 Ceaser AE, Goldberg TE, Egan MF, McMahon RP, Weinberger DR, Gold JM. Set-shifting ability and schizophrenia: a marker of clinical illness or an intermediate phenotype? Biological Psychiatry. 64: 782-8. PMID 18597738 DOI: 10.1016/j.biopsych.2008.05.009  1
2008 Matsumoto M, Straub RE, Marenco S, Nicodemus KK, Matsumoto S, Fujikawa A, Miyoshi S, Shobo M, Takahashi S, Yarimizu J, Yuri M, Hiramoto M, Morita S, Yokota H, Sasayama T, ... ... Egan MF, et al. The evolutionarily conserved G protein-coupled receptor SREB2/GPR85 influences brain size, behavior, and vulnerability to schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 105: 6133-8. PMID 18413613 DOI: 10.1073/pnas.0710717105  1
2008 Pezawas L, Meyer-Lindenberg A, Goldman AL, Verchinski BA, Chen G, Kolachana BS, Egan MF, Mattay VS, Hariri AR, Weinberger DR. Evidence of biologic epistasis between BDNF and SLC6A4 and implications for depression. Molecular Psychiatry. 13: 709-16. PMID 18347599 DOI: 10.1038/mp.2008.32  1
2008 Meyer-Lindenberg A, Nicodemus KK, Egan MF, Callicott JH, Mattay V, Weinberger DR. False positives in imaging genetics. Neuroimage. 40: 655-61. PMID 18201908 DOI: 10.1016/j.neuroimage.2007.11.058  1
2008 Nicodemus KK, Marenco S, Batten AJ, Vakkalanka R, Egan MF, Straub RE, Weinberger DR. Serious obstetric complications interact with hypoxia-regulated/vascular-expression genes to influence schizophrenia risk. Molecular Psychiatry. 13: 873-7. PMID 18195713 DOI: 10.1038/sj.mp.4002153  1
2008 Goldberg TE, Iudicello J, Russo C, Elvevåg B, Straub R, Egan MF, Weinberger DR. BDNF Val66Met polymorphism significantly affects d' in verbal recognition memory at short and long delays. Biological Psychology. 77: 20-4. PMID 17988784 DOI: 10.1016/j.biopsycho.2007.08.009  1
2008 Diaz-Asper CM, Goldberg TE, Kolachana BS, Straub RE, Egan MF, Weinberger DR. Genetic variation in catechol-O-methyltransferase: effects on working memory in schizophrenic patients, their siblings, and healthy controls. Biological Psychiatry. 63: 72-9. PMID 17707347 DOI: 10.1016/j.biopsych.2007.03.031  1
2008 Honea RA, Meyer-Lindenberg A, Hobbs KB, Pezawas L, Mattay VS, Egan MF, Verchinski B, Passingham RE, Weinberger DR, Callicott JH. Is gray matter volume an intermediate phenotype for schizophrenia? A voxel-based morphometry study of patients with schizophrenia and their healthy siblings. Biological Psychiatry. 63: 465-74. PMID 17689500 DOI: 10.1016/j.biopsych.2007.05.027  1
2008 Buckholtz JW, Callicott JH, Kolachana B, Hariri AR, Goldberg TE, Genderson M, Egan MF, Mattay VS, Weinberger DR, Meyer-Lindenberg A. Genetic variation in MAOA modulates ventromedial prefrontal circuitry mediating individual differences in human personality. Molecular Psychiatry. 13: 313-24. PMID 17519928 DOI: 10.1038/sj.mp.4002020  1
2008 Pezawas L, Meyer-Lindenberg A, Goldman AL, Verchinski BA, Chen G, Kolachana BS, Egan MF, Mattay VS, Hariri AR, Weinberger DR. MET BDNF protects against morphological S allele effects of 5-HTTLPR Molecular Psychiatry. 13: 654. DOI: 10.1038/mp.2008.61  1
2007 Straub RE, Lipska BK, Egan MF, Goldberg TE, Callicott JH, Mayhew MB, Vakkalanka RK, Kolachana BS, Kleinman JE, Weinberger DR. Allelic variation in GAD1 (GAD67) is associated with schizophrenia and influences cortical function and gene expression. Molecular Psychiatry. 12: 854-69. PMID 17767149 DOI: 10.1038/sj.mp.4001988  1
2007 Hyde TM, Goldberg TE, Egan MF, Lener MC, Weinberger DR. Frontal release signs and cognition in people with schizophrenia, their siblings and healthy controls. The British Journal of Psychiatry : the Journal of Mental Science. 191: 120-5. PMID 17666495 DOI: 10.1192/bjp.bp.106.026773  1
2007 Tan HY, Chen Q, Sust S, Buckholtz JW, Meyers JD, Egan MF, Mattay VS, Meyer-Lindenberg A, Weinberger DR, Callicott JH. Epistasis between catechol-O-methyltransferase and type II metabotropic glutamate receptor 3 genes on working memory brain function. Proceedings of the National Academy of Sciences of the United States of America. 104: 12536-41. PMID 17636131 DOI: 10.1073/pnas.0610125104  1
2007 Genderson MR, Dickinson D, Diaz-Asper CM, Egan MF, Weinberger DR, Goldberg TE. Factor analysis of neurocognitive tests in a large sample of schizophrenic probands, their siblings, and healthy controls. Schizophrenia Research. 94: 231-9. PMID 17570645 DOI: 10.1016/j.schres.2006.12.031  1
2007 Sei Y, Ren-Patterson R, Li Z, Tunbridge EM, Egan MF, Kolachana BS, Weinberger DR. Neuregulin1-induced cell migration is impaired in schizophrenia: association with neuregulin1 and catechol-o-methyltransferase gene polymorphisms. Molecular Psychiatry. 12: 946-57. PMID 17440436 DOI: 10.1038/sj.mp.4001994  1
2007 Buckholtz JW, Meyer-Lindenberg A, Honea RA, Straub RE, Pezawas L, Egan MF, Vakkalanka R, Kolachana B, Verchinski BA, Sust S, Mattay VS, Weinberger DR, Callicott JH. Allelic variation in RGS4 impacts functional and structural connectivity in the human brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 1584-93. PMID 17301167 DOI: 10.1523/JNEUROSCI.5112-06.2007  1
2007 Meyer-Lindenberg A, Straub RE, Lipska BK, Verchinski BA, Goldberg T, Callicott JH, Egan MF, Huffaker SS, Mattay VS, Kolachana B, Kleinman JE, Weinberger DR. Genetic evidence implicating DARPP-32 in human frontostriatal structure, function, and cognition. The Journal of Clinical Investigation. 117: 672-82. PMID 17290303 DOI: 10.1172/JCI30413  1
2007 Apud JA, Mattay V, Chen J, Kolachana BS, Callicott JH, Rasetti R, Alce G, Iudicello JE, Akbar N, Egan MF, Goldberg TE, Weinberger DR. Tolcapone improves cognition and cortical information processing in normal human subjects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1011-20. PMID 17063156 DOI: 10.1038/sj.npp.1301227  1
2007 Nicodemus KK, Kolachana BS, Vakkalanka R, Straub RE, Giegling I, Egan MF, Rujescu D, Weinberger DR. Evidence for statistical epistasis between catechol-O-methyltransferase (COMT) and polymorphisms in RGS4, G72 (DAOA), GRM3, and DISC1: influence on risk of schizophrenia. Human Genetics. 120: 889-906. PMID 17006672 DOI: 10.1007/s00439-006-0257-3  1
2006 Drabant EM, Hariri AR, Meyer-Lindenberg A, Munoz KE, Mattay VS, Kolachana BS, Egan MF, Weinberger DR. Catechol O-methyltransferase val158met genotype and neural mechanisms related to affective arousal and regulation. Archives of General Psychiatry. 63: 1396-406. PMID 17146014 DOI: 10.1001/archpsyc.63.12.1396  1
2006 Nicodemus KK, Luna A, Vakkalanka R, Goldberg T, Egan M, Straub RE, Weinberger DR. Further evidence for association between ErbB4 and schizophrenia and influence on cognitive intermediate phenotypes in healthy controls. Molecular Psychiatry. 11: 1062-5. PMID 17130882 DOI: 10.1038/sj.mp.4001878  1
2006 Tan HY, Sust S, Buckholtz JW, Mattay VS, Meyer-Lindenberg A, Egan MF, Weinberger DR, Callicott JH. Dysfunctional prefrontal regional specialization and compensation in schizophrenia. The American Journal of Psychiatry. 163: 1969-77. PMID 17074949 DOI: 10.1176/appi.ajp.163.11.1969  1
2006 Winterer G, Musso F, Beckmann C, Mattay V, Egan MF, Jones DW, Callicott JH, Coppola R, Weinberger DR. Instability of prefrontal signal processing in schizophrenia. The American Journal of Psychiatry. 163: 1960-8. PMID 17074948 DOI: 10.1176/appi.ajp.163.11.1960  1
2006 Meyer-Lindenberg A, Nichols T, Callicott JH, Ding J, Kolachana B, Buckholtz J, Mattay VS, Egan M, Weinberger DR. Impact of complex genetic variation in COMT on human brain function. Molecular Psychiatry. 11: 867-77, 797. PMID 16786032 DOI: 10.1038/sj.mp.4001860  1
2006 Winterer G, Egan MF, Kolachana BS, Goldberg TE, Coppola R, Weinberger DR. Prefrontal electrophysiologic "noise" and catechol-O-methyltransferase genotype in schizophrenia. Biological Psychiatry. 60: 578-84. PMID 16730334 DOI: 10.1016/j.biopsych.2006.03.023  1
2006 Talkowski ME, Seltman H, Bassett AS, Brzustowicz LM, Chen X, Chowdari KV, Collier DA, Cordeiro Q, Corvin AP, Deshpande SN, Egan MF, Gill M, Kendler KS, Kirov G, Heston LL, et al. Evaluation of a susceptibility gene for schizophrenia: genotype based meta-analysis of RGS4 polymorphisms from thirteen independent samples. Biological Psychiatry. 60: 152-62. PMID 16631129 DOI: 10.1016/j.biopsych.2006.02.015  1
2006 Marenco S, Steele SU, Egan MF, Goldberg TE, Straub RE, Sharrief AZ, Weinberger DR. Effect of metabotropic glutamate receptor 3 genotype on N-acetylaspartate measures in the dorsolateral prefrontal cortex. The American Journal of Psychiatry. 163: 740-2. PMID 16585454 DOI: 10.1176/appi.ajp.163.4.740  1
2006 Meyer-Lindenberg A, Buckholtz JW, Kolachana B, R Hariri A, Pezawas L, Blasi G, Wabnitz A, Honea R, Verchinski B, Callicott JH, Egan M, Mattay V, Weinberger DR. Neural mechanisms of genetic risk for impulsivity and violence in humans. Proceedings of the National Academy of Sciences of the United States of America. 103: 6269-74. PMID 16569698 DOI: 10.1073/pnas.0511311103  1
2006 Goldberg TE, Straub RE, Callicott JH, Hariri A, Mattay VS, Bigelow L, Coppola R, Egan MF, Weinberger DR. The G72/G30 gene complex and cognitive abnormalities in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2022-32. PMID 16554747 DOI: 10.1038/sj.npp.1301049  1
2006 Chrapusta SJ, Egan MF. Poor evidence for depolarization block but uncoupling of nigral from striatal dopamine metabolism after chronic haloperidol treatment in the rat. Journal of Neural Transmission (Vienna, Austria : 1996). 113: 573-82. PMID 16082510 DOI: 10.1007/s00702-005-0347-8  1
2006 Meyer-Lindenberg A, Nichols T, Callicott JH, Ding J, Kolachana B, Buckholtz J, Mattay VS, Egan M, Weinberger DR. COMT haplotype variation affects human prefrontal function Molecular Psychiatry. 11: 797. DOI: 10.1038/sj.mp.4001881  1
2005 Callicott JH, Straub RE, Pezawas L, Egan MF, Mattay VS, Hariri AR, Verchinski BA, Meyer-Lindenberg A, Balkissoon R, Kolachana B, Goldberg TE, Weinberger DR. Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 102: 8627-32. PMID 15939883 DOI: 10.1073/pnas.0500515102  1
2005 Blasi G, Mattay VS, Bertolino A, Elvevåg B, Callicott JH, Das S, Kolachana BS, Egan MF, Goldberg TE, Weinberger DR. Effect of catechol-O-methyltransferase val158met genotype on attentional control. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5038-45. PMID 15901785 DOI: 10.1523/JNEUROSCI.0476-05.2005  1
2005 Pezawas L, Meyer-Lindenberg A, Drabant EM, Verchinski BA, Munoz KE, Kolachana BS, Egan MF, Mattay VS, Hariri AR, Weinberger DR. 5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression. Nature Neuroscience. 8: 828-34. PMID 15880108 DOI: 10.1038/nn1463  1
2005 Meyer-Lindenberg AS, Olsen RK, Kohn PD, Brown T, Egan MF, Weinberger DR, Berman KF. Regionally specific disturbance of dorsolateral prefrontal-hippocampal functional connectivity in schizophrenia. Archives of General Psychiatry. 62: 379-86. PMID 15809405 DOI: 10.1001/archpsyc.62.4.379  1
2005 Hariri AR, Drabant EM, Munoz KE, Kolachana BS, Mattay VS, Egan MF, Weinberger DR. A susceptibility gene for affective disorders and the response of the human amygdala. Archives of General Psychiatry. 62: 146-52. PMID 15699291 DOI: 10.1001/archpsyc.62.2.146  1
2005 Sporn A, Greenstein D, Gogtay N, Sailer F, Hommer DW, Rawlings R, Nicolson R, Egan MF, Lenane M, Gochman P, Weinberger DR, Rapoport JL. Childhood-onset schizophrenia: smooth pursuit eye-tracking dysfunction in family members. Schizophrenia Research. 73: 243-52. PMID 15653267 DOI: 10.1016/j.schres.2004.07.020  1
2005 Egan MF. Neuroimaging the genetic effects of brain-derived neurotrophic factor on human hippocampus Dialogues in Clinical Neuroscience. 7: 136-138.  1
2004 Pezawas L, Verchinski BA, Mattay VS, Callicott JH, Kolachana BS, Straub RE, Egan MF, Meyer-Lindenberg A, Weinberger DR. The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10099-102. PMID 15537879 DOI: 10.1523/JNEUROSCI.2680-04.2004  1
2004 Weickert TW, Goldberg TE, Mishara A, Apud JA, Kolachana BS, Egan MF, Weinberger DR. Catechol-O-methyltransferase val108/158met genotype predicts working memory response to antipsychotic medications. Biological Psychiatry. 56: 677-82. PMID 15522252 DOI: 10.1016/j.biopsych.2004.08.012  1
2004 Chen J, Lipska BK, Halim N, Ma QD, Matsumoto M, Melhem S, Kolachana BS, Hyde TM, Herman MM, Apud J, Egan MF, Kleinman JE, Weinberger DR. Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain. American Journal of Human Genetics. 75: 807-21. PMID 15457404 DOI: 10.1086/425589  1
2004 Egan MF, Straub RE, Goldberg TE, Yakub I, Callicott JH, Hariri AR, Mattay VS, Bertolino A, Hyde TM, Shannon-Weickert C, Akil M, Crook J, Vakkalanka RK, Balkissoon R, Gibbs RA, et al. Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 101: 12604-9. PMID 15310849 DOI: 10.1073/pnas.0405077101  1
2004 Winterer G, Coppola R, Goldberg TE, Egan MF, Jones DW, Sanchez CE, Weinberger DR. Prefrontal broadband noise, working memory, and genetic risk for schizophrenia. The American Journal of Psychiatry. 161: 490-500. PMID 14992975 DOI: 10.1176/appi.ajp.161.3.490  1
2003 Winterer G, Coppola R, Egan MF, Goldberg TE, Weinberger DR. Functional and effective frontotemporal connectivity and genetic risk for schizophrenia. Biological Psychiatry. 54: 1181-92. PMID 14643085 DOI: 10.1016/S0006-3223(03)00532-8  1
2003 Callicott JH, Mattay VS, Verchinski BA, Marenco S, Egan MF, Weinberger DR. Complexity of prefrontal cortical dysfunction in schizophrenia: more than up or down. The American Journal of Psychiatry. 160: 2209-15. PMID 14638592 DOI: 10.1176/appi.ajp.160.12.2209  1
2003 Winterer G, Egan MF, Raedler T, Sanchez C, Jones DW, Coppola R, Weinberger DR. P300 and genetic risk for schizophrenia. Archives of General Psychiatry. 60: 1158-67. PMID 14609891 DOI: 10.1001/archpsyc.60.11.1158  1
2003 Goldberg TE, Egan MF, Gscheidle T, Coppola R, Weickert T, Kolachana BS, Goldman D, Weinberger DR. Executive subprocesses in working memory: relationship to catechol-O-methyltransferase Val158Met genotype and schizophrenia. Archives of General Psychiatry. 60: 889-96. PMID 12963670 DOI: 10.1001/archpsyc.60.9.889  1
2003 Apud JA, Egan MF, Wyatt RJ. Neuroleptic withdrawal in treatment-resistant patients with schizophrenia: tardive dyskinesia is not associated with supersensitive psychosis. Schizophrenia Research. 63: 151-60. PMID 12892869 DOI: 10.1016/S0920-9964(02)00338-9  1
2003 Hariri AR, Goldberg TE, Mattay VS, Kolachana BS, Callicott JH, Egan MF, Weinberger DR. Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 6690-4. PMID 12890761  1
2003 Egan MF, Weinberger DR, Lu B. Schizophrenia, III: brain-derived neurotropic factor and genetic risk. The American Journal of Psychiatry. 160: 1242. PMID 12832235  1
2003 Weickert TW, Goldberg TE, Marenco S, Bigelow LB, Egan MF, Weinberger DR. Comparison of cognitive performances during a placebo period and an atypical antipsychotic treatment period in schizophrenia: critical examination of confounds. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1491-500. PMID 12799617 DOI: 10.1038/sj.npp.1300216  1
2003 Raedler TJ, Knable MB, Jones DW, Urbina RA, Egan MF, Weinberger DR. Central muscarinic acetylcholine receptor availability in patients treated with clozapine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1531-7. PMID 12799613 DOI: 10.1038/sj.npp.1300210  1
2003 Mattay VS, Goldberg TE, Fera F, Hariri AR, Tessitore A, Egan MF, Kolachana B, Callicott JH, Weinberger DR. Catechol O-methyltransferase val158-met genotype and individual variation in the brain response to amphetamine. Proceedings of the National Academy of Sciences of the United States of America. 100: 6186-91. PMID 12716966 DOI: 10.1073/pnas.0931309100  1
2003 Callicott JH, Egan MF, Mattay VS, Bertolino A, Bone AD, Verchinksi B, Weinberger DR. Abnormal fMRI response of the dorsolateral prefrontal cortex in cognitively intact siblings of patients with schizophrenia. The American Journal of Psychiatry. 160: 709-19. PMID 12668360 DOI: 10.1176/appi.ajp.160.4.709  1
2003 Nicolson R, Brookner FB, Lenane M, Gochman P, Ingraham LJ, Egan MF, Kendler KS, Pickar D, Weinberger DR, Rapoport JL. Parental schizophrenia spectrum disorders in childhood-onset and adult-onset schizophrenia. The American Journal of Psychiatry. 160: 490-5. PMID 12611830 DOI: 10.1176/appi.ajp.160.3.490  1
2003 Egan MF, Kojima M, Callicott JH, Goldberg TE, Kolachana BS, Bertolino A, Zaitsev E, Gold B, Goldman D, Dean M, Lu B, Weinberger DR. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell. 112: 257-69. PMID 12553913 DOI: 10.1016/S0092-8674(03)00035-7  1
2003 Chrapusta SJ, Egan MF, Wyatt RJ, Weinberger DR, Lipska BK. Neonatal ventral hippocampal damage modifies serum corticosterone and dopamine release responses to acute footshock in adult Sprague-Dawley rats. Synapse (New York, N.Y.). 47: 270-7. PMID 12539200 DOI: 10.1002/syn.10179  1
2003 Raedler TJ, Knable MB, Jones DW, Urbina RA, Gorey JG, Lee KS, Egan MF, Coppola R, Weinberger DR. In vivo determination of muscarinic acetylcholine receptor availability in schizophrenia. The American Journal of Psychiatry. 160: 118-27. PMID 12505810 DOI: 10.1176/appi.ajp.160.1.118  1
2003 Egan MF, Goldberg TE. Intermediate cognitive phenotypes associated with schizophrenia. Methods in Molecular Medicine. 77: 163-97. PMID 12298369  1
2002 Weickert TW, Terrazas A, Bigelow LB, Malley JD, Hyde T, Egan MF, Weinberger DR, Goldberg TE. Habit and skill learning in schizophrenia: evidence of normal striatal processing with abnormal cortical input. Learning & Memory (Cold Spring Harbor, N.Y.). 9: 430-42. PMID 12464703 DOI: 10.1101/lm.49102  1
2002 Marenco S, Egan MF, Goldberg TE, Knable MB, McClure RK, Winterer G, Weinberger DR. Preliminary experience with an ampakine (CX516) as a single agent for the treatment of schizophrenia: a case series. Schizophrenia Research. 57: 221-6. PMID 12223253 DOI: 10.1016/S0920-9964(01)00311-5  1
2002 Hariri AR, Mattay VS, Tessitore A, Kolachana B, Fera F, Goldman D, Egan MF, Weinberger DR. Serotonin transporter genetic variation and the response of the human amygdala. Science (New York, N.Y.). 297: 400-3. PMID 12130784 DOI: 10.1126/science.1071829  1
2002 Hamid EH, Hyde TM, Egan MF, Wolf SS, Herman MM, Nemeroff CB, Kleinman JE. Neurotensin receptor binding abnormalities in the entorhinal cortex in schizophrenia and affective disorders. Biological Psychiatry. 51: 795-800. PMID 12007453 DOI: 10.1016/S0006-3223(01)01325-7  1
2002 Egan M, Goldman D, Weinberger D. The human genome: mutations American Journal of Psychiatry. 159: 12. PMID 11772682  1
2001 Weinberger DR, Egan MF, Bertolino A, Callicott JH, Mattay VS, Lipska BK, Berman KF, Goldberg TE. Prefrontal neurons and the genetics of schizophrenia. Biological Psychiatry. 50: 825-44. PMID 11743939 DOI: 10.1016/S0006-3223(01)01252-5  1
2001 Egan MF, Hyde TM, Bonomo JB, Mattay VS, Bigelow LB, Goldberg TE, Weinberger DR. Relative risk of neurological signs in siblings of patients with schizophrenia. The American Journal of Psychiatry. 158: 1827-34. PMID 11691688 DOI: 10.1176/appi.ajp.158.11.1827  1
2001 Meyer-Lindenberg A, Poline JB, Kohn PD, Holt JL, Egan MF, Weinberger DR, Berman KF. Evidence for abnormal cortical functional connectivity during working memory in schizophrenia. The American Journal of Psychiatry. 158: 1809-17. PMID 11691686 DOI: 10.1176/appi.ajp.158.11.1809  1
2001 Winterer G, Egan MF, Rädler T, Coppola R, Weinberger DR. Event-related potentials and genetic risk for schizophrenia. Biological Psychiatry. 50: 407-17. PMID 11566157 DOI: 10.1016/S0006-3223(01)01072-1  1
2001 Egan MF, Goldberg TE, Gscheidle T, Weirich M, Rawlings R, Hyde TM, Bigelow L, Weinberger DR. Relative risk for cognitive impairments in siblings of patients with schizophrenia. Biological Psychiatry. 50: 98-107. PMID 11527000 DOI: 10.1016/S0006-3223(01)01133-7  1
2001 Egan MF, Goldberg TE, Kolachana BS, Callicott JH, Mazzanti CM, Straub RE, Goldman D, Weinberger DR. Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 98: 6917-22. PMID 11381111 DOI: 10.1073/pnas.111134598  1
2001 Winterer G, Egan MF, Rädler T, Hyde T, Coppola R, Weinberger DR. An association between reduced interhemispheric EEG coherence in the temporal lobe and genetic risk for schizophrenia. Schizophrenia Research. 49: 129-43. PMID 11343872 DOI: 10.1016/S0920-9964(00)00128-6  1
2001 Bertolino A, Callicott JH, Mattay VS, Weidenhammer KM, Rakow R, Egan MF, Weinberger DR. The effect of treatment with antipsychotic drugs on brain N-acetylaspartate measures in patients with schizophrenia. Biological Psychiatry. 49: 39-46. PMID 11163778 DOI: 10.1016/S0006-3223(00)00997-5  1
2001 Dawson NM, Hamid EH, Egan MF, Meredith GE. Changes in the pattern of brain-derived neurotrophic factor immunoreactivity in the rat brain after acute and subchronic haloperidol treatment. Synapse (New York, N.Y.). 39: 70-81. PMID 11071712 DOI: 10.1002/1098-2396(20010101)39:1<70::AID-SYN10>3.0.CO;2-J  0.4
2001 Xu H, Hashimoto A, Rice KC, Jacobson AE, Thomas JB, Carroll FI, Lai J, Rothman RB. Opioid peptide receptor studies. 14. Stereochemistry determines agonist efficacy and intrinsic efficacy in the [(35)S]GTP-gamma-S functional binding assay. Synapse (New York, N.Y.). 39: 64-9. PMID 11071711 DOI: 10.1002/1098-2396(20010101)39:1<64::AID-SYN9>3.0.CO;2-J  1
2000 Goldberg TE, Dodge M, Aloia M, Egan MF, Weinberger DR. Effects of neuroleptic medications on speech disorganization in schizophrenia: biasing associative networks towards meaning. Psychological Medicine. 30: 1123-30. PMID 12027048 DOI: 10.1017/S0033291799002639  1
2000 ElvevÃ¥g B, Egan MF, Goldberg TE. Memory for temporal order in patients with schizophrenia. Schizophrenia Research. 46: 187-93. PMID 11120430 DOI: 10.1016/S0920-9964(00)00014-1  1
2000 Apud JA, Egan MF, Wyatt RJ. Effects of smoking during antipsychotic withdrawal in patients with chronic schizophrenia. Schizophrenia Research. 46: 119-27. PMID 11120424 DOI: 10.1016/S0920-9964(99)00230-3  1
2000 ElvevÃ¥g B, Egan MF, Goldberg TE. Paired-associate learning and memory interference in schizophrenia. Neuropsychologia. 38: 1565-75. PMID 11074079 DOI: 10.1016/S0028-3932(00)00074-9  1
2000 Meredith GE, De Souza IE, Hyde TM, Tipper G, Wong ML, Egan MF. Persistent alterations in dendrites, spines, and dynorphinergic synapses in the nucleus accumbens shell of rats with neuroleptic-induced dyskinesias. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7798-806. PMID 11027244  1
2000 Callicott JH, Bertolino A, Egan MF, Mattay VS, Langheim FJ, Weinberger DR. Selective relationship between prefrontal N-acetylaspartate measures and negative symptoms in schizophrenia. The American Journal of Psychiatry. 157: 1646-51. PMID 11007719 DOI: 10.1176/appi.ajp.157.10.1646  1
2000 Weickert TW, Goldberg TE, Gold JM, Bigelow LB, Egan MF, Weinberger DR. Cognitive impairments in patients with schizophrenia displaying preserved and compromised intellect. Archives of General Psychiatry. 57: 907-13. PMID 10986554  1
2000 Bower CM, Hyde TM, Zaka M, Hamid EH, Baca SM, Egan MF. Decreased mu-opioid receptor binding in the globus pallidus of rats treated with chronic haloperidol. Psychopharmacology. 150: 260-3. PMID 10923753 DOI: 10.1007/s002130000460  1
2000 Egan MF, Goldberg TE, Gscheidle T, Weirich M, Bigelow LB, Weinberger DR. Relative risk of attention deficits in siblings of patients with schizophrenia. The American Journal of Psychiatry. 157: 1309-16. PMID 10910796 DOI: 10.1176/appi.ajp.157.8.1309  1
2000 Raedler TJ, Knable MB, Jones DW, Lafargue T, Urbina RA, Egan MF, Pickar D, Weinberger DR. In vivo olanzapine occupancy of muscarinic acetylcholine receptors in patients with schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 23: 56-68. PMID 10869886 DOI: 10.1016/S0893-133X(99)00162-1  1
2000 Japee S, Meyer-Lindenberg A, Verchinski B, Kohn P, Egan M, Bigelow L, Callicott J, Bertolino A, Mattay V, Weinberger D, Berman K. Development of a template-based quantitative volumetric method: Application to structural MRI data from schizophrenic patients, their siblings and normal controls Neuroimage. 11: S545.  1
2000 Verchinski B, Meyer-Lindenberg A, Japee S, Kohn P, Egan M, Bigelow L, Callicott J, Bertolino A, Mattay V, Berman K, Weinberger D. Gender differences in gray matter density: A study of structural mri images using voxel-based morphometry Neuroimage. 11: S228.  1
2000 Meyer-Lindenberg A, Kohn P, Holt J, Egan M, Weinberger D, Berman KF. Disturbed connectivity in schizophrenia: PET studies Neuroimage. 11: S186.  1
2000 Meyer-Lindenberg A, Japee S, Verchinski B, Kohn P, Egan M, Bigelow L, Callicott J, Bertolino A, Mattay V, Berman KF, Weinberger D. Structural MRI abnormalities in schizophrenic patients and their unaffected siblings: Voxel-based morphometry Neuroimage. 11: S217.  1
1999 Raedler TJ, Knable MB, Lafargue T, Urbina RA, Egan MF, Pickar D, Weinberger DR. In vivo determination of striatal dopamine D2 receptor occupancy in patients treated with olanzapine. Psychiatry Research. 90: 81-90. PMID 10482380 DOI: 10.1016/S0925-4927(99)00010-4  1
1998 Callicott JH, Egan MF, Bertolino A, Mattay VS, Langheim FJ, Frank JA, Weinberger DR. Hippocampal N-acetyl aspartate in unaffected siblings of patients with schizophrenia: a possible intermediate neurobiological phenotype. Biological Psychiatry. 44: 941-50. PMID 9821558 DOI: 10.1016/S0006-3223(98)00264-9  1
1998 Hamid EH, Hyde TM, Baca SM, Egan MF. Failure to down regulate NMDA receptors in the striatum and nucleus accumbens associated with neuroleptic-induced dyskinesia. Brain Research. 796: 291-5. PMID 9689480 DOI: 10.1016/S0006-8993(98)00196-6  1
1998 Baca SM, Lipska BK, Egan MF, Bachus SE, Ferguson JN, Hyde TM. Effects of prefrontal cortical lesions on neuropeptide and dopamine receptor gene expression in the striatum-accumbens complex. Brain Research. 797: 55-64. PMID 9630515 DOI: 10.1016/S0006-8993(98)00343-6  1
1998 Callicott JH, Egan MF, Mattay VS, Bertolino A, Jones KM, Goldberg TE, Weinberger DR. Altered prefrontal cortical function in unaffected siblings of patients with schizophrenia Neuroimage. 7: S895.  1
1998 Hamid EH, Egan MF, Dickson LA. Detrimental effects of short term haloperidol treatment and withdrawal on striatal BDNF gene expression Faseb Journal. 12: A758.  1
1997 Knable MB, Egan MF, Heinz A, Gorey J, Lee KS, Coppola R, Weinberger DR. Altered dopaminergic function and negative symptoms in drug-free patients with schizophrenia. [123I]-iodobenzamide SPECT study. The British Journal of Psychiatry : the Journal of Mental Science. 171: 574-7. PMID 9519100  1
1997 Egan MF, Weinberger DR. Neurobiology of schizophrenia. Current Opinion in Neurobiology. 7: 701-7. PMID 9384552 DOI: 10.1016/S0959-4388(97)80092-X  1
1997 Egan MF, Apud J, Wyatt RJ. Treatment of tardive dyskinesia. Schizophrenia Bulletin. 23: 583-609. PMID 9365997  1
1997 Bachus SE, Hyde TM, Herman MM, Egan MF, Kleinman JE. Abnormal cholecystokinin mRNA levels in entorhinal cortex of schizophrenics. Journal of Psychiatric Research. 31: 233-56. PMID 9278188 DOI: 10.1016/S0022-3956(96)00041-6  1
1996 Egan MF, Hurd Y, Ferguson J, Bachus SE, Hamid EH, Hyde TM. Pharmacological and neurochemical differences between acute and tardive vacuous chewing movements induced by haloperidol. Psychopharmacology. 127: 337-45. PMID 8923569 DOI: 10.1007/s002130050095  1
1996 Egan MF, Chrapusta S, Karoum F, Lipska BK, Wyatt RJ. Effects of chronic neuroleptic treatment on dopamine release: insights from studies using 3-methoxytyramine. Journal of Neural Transmission (Vienna, Austria : 1996). 103: 777-805. PMID 8872864 DOI: 10.1007/BF01273358  1
1996 Egan MF, Chrapusta SJ, Karoum F, Wyatt RJ. The effects of acute and chronic haloperidol treatment on dopamine release mediated by the medial forebrain bundle in the striatum and nucleus accumbens. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 14: 211-23. PMID 8866705 DOI: 10.1016/0893-133X(95)00111-P  1
1996 Egan MF, Ferguson J, Hyde TM. Effects of rating parameters on assessment of neuroleptic-induced vacuous chewing movements. Pharmacology, Biochemistry, and Behavior. 53: 401-10. PMID 8808150 DOI: 10.1016/0091-3057(95)02041-1  1
1995 Egan MF, Ferguson JN, Hyde TM. Effects of chronic naloxone administration on vacuous chewing movements and catalepsy in rats treated with long-term haloperidol decanoate. Brain Research Bulletin. 38: 355-63. PMID 8535858 DOI: 10.1016/0361-9230(95)00108-Q  1
1995 Hyde TM, Egan MF, Brown RJ, Weinberger DR, Kleinman JE. Diurnal variation in tardive dyskinesia. Psychiatry Research. 56: 53-7. PMID 7792342 DOI: 10.1016/0165-1781(94)02662-3  1
1995 Egan MF, Hyde TM, Kleinman JE, Wyatt RJ. Neuroleptic-induced vacuous chewing movements in rodents: incidence and effects of long-term increases in haloperidol dose. Psychopharmacology. 117: 74-81. PMID 7724705 DOI: 10.1007/BF02245101  1
1995 Hyde TM, Egan MF, Wing LL, Wyatt RJ, Weinberger DR, Kleinman JE. Persistent catalepsy associated with severe dyskinesias in rats treated with chronic injections of haloperidol decanoate. Psychopharmacology. 118: 142-9. PMID 7617800 DOI: 10.1007/BF02245832  1
1995 Bartzokis G, Marder SR, Elkashef AM, Egan MF, Frank JA, Hyde TM, Lewis BK, Wyatt RJ. Magnetic resonance imaging evaluation of brain iron levels Biological Psychiatry. 38: 133-135. PMID 7578650 DOI: 10.1016/0006-3223(95)00036-G  1
1995 Lipska BK, Chrapusta SJ, Egan MF, Weinberger DR. Neonatal excitotoxic ventral hippocampal damage alters dopamine response to mild repeated stress and to chronic haloperidol. Synapse (New York, N.Y.). 20: 125-30. PMID 7570341 DOI: 10.1002/syn.890200205  1
1994 Karoum F, Egan MF, Wyatt RJ. Selective reduction in dopamine turnover in the rat frontal cortex and hypothalamus during withdrawal from repeated cocaine exposure. European Journal of Pharmacology. 254: 127-32. PMID 8206108 DOI: 10.1016/0014-2999(94)90379-4  1
1994 Elkashef AM, Egan MF, Frank JA, Hyde TM, Lewis BK, Wyatt RJ. Basal ganglia iron in tardive dyskinesia: an MRI study. Biological Psychiatry. 35: 16-21. PMID 8167198 DOI: 10.1016/0006-3223(94)91161-4  1
1994 Knable MB, Hyde TM, Egan MF, Tosayali M, Wyatt RJ, Kleinman JE. Quantitative autoradiography of striatal dopamine D1, D2 and re-uptake sites in rats with vacuous chewing movements. Brain Research. 646: 217-22. PMID 8069667 DOI: 10.1016/0006-8993(94)90081-7  1
1994 Karoum F, Chrapusta SJ, Egan MF. 3-Methoxytyramine is the major metabolite of released dopamine in the rat frontal cortex: reassessment of the effects of antipsychotics on the dynamics of dopamine release and metabolism in the frontal cortex, nucleus accumbens, and striatum by a simple two pool model. Journal of Neurochemistry. 63: 972-9. PMID 7914228  1
1994 Egan MF, Duncan CC, Suddath RL, Kirch DG, Mirsky AF, Wyatt RJ. Event-related potential abnormalities correlate with structural brain alterations and clinical features in patients with chronic schizophrenia. Schizophrenia Research. 11: 259-71. PMID 7910755 DOI: 10.1016/0920-9964(94)90020-5  1
1994 Chrapusta SJ, Egan MF, Masserano JM, Wyatt RJ. Dopamine release in the rat cerebellum and hippocampus: a tissue 3-methoxytyramine study. Brain Research. 655: 271-5. PMID 7812787 DOI: 10.1016/0006-8993(94)91627-6  1
1994 Egan MF, Hurd Y, Hyde TM, Weinberger DR, Wyatt RJ, Kleinman JE. Alterations in mRNA levels of D2 receptors and neuropeptides in striatonigral and striatopallidal neurons of rats with neuroleptic-induced dyskinesias. Synapse (New York, N.Y.). 18: 178-89. PMID 7531873 DOI: 10.1002/syn.890180303  1
1994 Egan MF, Wing L, Li R, Kirch DG, Wyatt RJ. Effects of chronic cocaine treatment on rat brain: long-term reduction in frontal cortical serotonin. Biological Psychiatry. 36: 637-40. PMID 7530497 DOI: 10.1016/0006-3223(94)90079-5  1
1993 Chrapusta SJ, Karoum F, Egan MF, Wyatt RJ. Haloperidol and clozapine increase intraneuronal dopamine metabolism, but not gamma-butyrolactone-resistant dopamine release. European Journal of Pharmacology. 233: 135-42. PMID 8472742 DOI: 10.1016/0014-2999(93)90359-P  1
1993 Karoum F, Chrapusta SJ, Egan MF, Wyatt RJ. Absence of 6-hydroxydopamine in the rat brain after treatment with stimulants and other dopaminergic agents: a mass fragmentographic study. Journal of Neurochemistry. 61: 1369-75. PMID 8104232  1
1993 Egan MF, Dargham AA, Kirch DG, Wyatt RJ. Serum creatine phosphokinase elevations in patients with tardive dyskinesia. The British Journal of Psychiatry : the Journal of Mental Science. 162: 551-3. PMID 8097656  1
1993 Gupta S, Egan MF, Hyde TM. An unusual presentation of tardive dyskinesia with prominent involvement of the pectoral musculature. Biological Psychiatry. 33: 291-2. PMID 8097115 DOI: 10.1016/0006-3223(93)90297-Q  1
1992 Karoum F, Egan MF. Dopamine release and metabolism in the rat frontal cortex, nucleus accumbens, and striatum: a comparison of acute clozapine and haloperidol. British Journal of Pharmacology. 105: 703-7. PMID 1628156  1
1992 Egan MF, Hyde TM, Tirschwell DL, Kleinman JE, Weinberger DR. Laterality of appendicular tardive dyskinesia in chronic schizophrenia. Biological Psychiatry. 31: 1098-109. PMID 1525274 DOI: 10.1016/0006-3223(92)90154-R  1
1992 Chrapusta SJ, Karoum F, Egan MF, Wyatt RJ. gamma-Butyrolactone-sensitive and -insensitive dopamine release, and their relationship to dopamine metabolism in three rat brain regions. European Journal of Pharmacology. 222: 129-35. PMID 1468488 DOI: 10.1016/0014-2999(92)90472-G  1
1992 Egan MF, el-Mallakh RS, Suddath RL, Lohr JB, Bracha HS, Wyatt RJ. Cerebrospinal fluid and serum levels of neuron-specific enolase in patients with schizophrenia. Psychiatry Research. 43: 187-95. PMID 1357702 DOI: 10.1016/0165-1781(92)90133-N  1
1992 Egan MF, Hyde TM, Albers GW, Elkashef A, Alexander RC, Reeve A, Blum A, Saenz RE, Wyatt RJ. Treatment of tardive dyskinesia with vitamin E. The American Journal of Psychiatry. 149: 773-7. PMID 1350428  1
1991 Egan MF, Karoum F, Wyatt RJ. Effects of acute and chronic clozapine and haloperidol administration on 3-methoxytyramine accumulation in rat prefrontal cortex, nucleus accumbens and striatum. European Journal of Pharmacology. 199: 191-9. PMID 1954977 DOI: 10.1016/0014-2999(91)90457-2  1
1991 Gold JM, Egan MF, Kirch DG, Goldberg TE, Daniel DG, Bigelow LB, Wyatt RJ. Tardive dyskinesia: neuropsychological, computerized tomographic, and psychiatric symptom findings. Biological Psychiatry. 30: 587-99. PMID 1681948 DOI: 10.1002/9780470753217.ch9  1
1988 Wyatt RJ, Alexander RC, Egan MF, Kirch DG. Schizophrenia, just the facts. What do we know, how well do we know it? Schizophrenia Research. 1: 3-18. PMID 3154503 DOI: 10.1016/0920-9964(88)90034-5  1
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