Year |
Citation |
Score |
2018 |
Aleem A, Tsai WC, Tena J, Alvarez G, Deschamps J, Kalyanaraman C, Jacobson MP, Holman TR. Probing the Electrostatic and Steric Requirements for Substrate Binding in Human Platelet-type 12-Lipoxygenase. Biochemistry. PMID 30565457 DOI: 10.1021/Acs.Biochem.8B01167 |
0.387 |
|
2016 |
Armstrong M, van Hoorebeke C, Horn T, Deschamps J, Freedman JC, Kalyanaraman C, Jacobson MP, Holman T. Human 15-LOX-1 active site mutations alter inhibitor binding and decrease potency. Bioorganic & Medicinal Chemistry. PMID 27647374 DOI: 10.1016/J.Bmc.2016.08.063 |
0.411 |
|
2016 |
Deschamps JD, Ogunsola AF, Jameson JB, Yasgar A, Flitter BA, Freedman CJ, Melvin JA, Maloney DJ, Jadhav A, Simeonov A, Bomberger JM, Holman TR, Nguyen JV. Biochemical/Cellular Characterization and Inhibitor discovery of Pseudomonas aeruginosa 15-Lipoxygenase. Biochemistry. PMID 27226387 DOI: 10.1021/Acs.Biochem.6B00338 |
0.362 |
|
2009 |
Wecksler AT, Kenyon V, Garcia NK, Deschamps JD, Van Der Donk WA, Holman TR. Kinetic and structural investigations of the allosteric site in human epithelial 15-lipoxygenase-2 Biochemistry. 48: 8721-8730. PMID 19645454 DOI: 10.1021/Bi9009242 |
0.374 |
|
2008 |
Wecksler AT, Kenyon V, Deschamps JD, Holman TR. Substrate specificity changes for human reticulocyte and epithelial 15-lipoxygenases reveal allosteric product regulation Biochemistry. 47: 7364-7375. PMID 18570379 DOI: 10.1021/Bi800550N |
0.312 |
|
2007 |
Deschamps JD, Gautschi JT, Whitman S, Johnson TA, Gassner NC, Crews P, Holman TR. Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries. Bioorganic & Medicinal Chemistry. 15: 6900-8. PMID 17826100 DOI: 10.1016/J.Bmc.2007.08.015 |
0.399 |
|
2006 |
Deschamps JD, Kenyon VA, Holman TR. Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases Bioorganic and Medicinal Chemistry. 14: 4295-4301. PMID 16500106 DOI: 10.1016/J.Bmc.2006.01.057 |
0.392 |
|
2004 |
Gutierrez-Lugo MT, Deschamps JD, Holman TR, Suarez E, Timmermann BN. Lipoxygenase inhibition by anadanthoflavone, a new flavonoid from the aerial parts of Anadenanthera colubrina Planta Medica. 70: 263-265. PMID 15114507 DOI: 10.1055/S-2004-818920 |
0.328 |
|
Show low-probability matches. |