Sarah Threlfell - Publications


28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bengoa-Vergniory N, Faggiani E, Ramos-Gonzalez P, Kirkiz E, Connor-Robson N, Brown LV, Siddique I, Li Z, Vingill S, Cioroch M, Cavaliere F, Threlfell S, Roberts B, Schrader T, Klärner FG, et al. CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease. Nature Communications. 11: 4885. PMID 32985503 DOI: 10.1038/s41467-020-18689-x  0.64
2019 Kosillo P, Doig NM, Ahmed KM, Agopyan-Miu AHCW, Wong CD, Conyers L, Threlfell S, Magill PJ, Bateup HS. Tsc1-mTORC1 signaling controls striatal dopamine release and cognitive flexibility. Nature Communications. 10: 5426. PMID 31780742 DOI: 10.1038/S41467-019-13396-8  0.64
2019 Hunn BHM, Vingill S, Threlfell S, Alegre-Abarrategui J, Magdelyns M, Deltheil T, Bengoa-Vergniory N, Oliver PL, Cioroch M, Doig NM, Bannerman DM, Cragg SJ, Wade-Martins R. Impairment of Macroautophagy in Dopamine Neurons Has Opposing Effects on Parkinsonian Pathology and Behavior. Cell Reports. 29: 920-931.e7. PMID 31644913 DOI: 10.1016/J.Celrep.2019.09.029  0.64
2019 Condon MD, Platt NJ, Zhang YF, Roberts BM, Clements MA, Vietti-Michelina S, Tseu MY, Brimblecombe KR, Threlfell S, Mann EO, Cragg SJ. Plasticity in striatal dopamine release is governed by release-independent depression and the dopamine transporter. Nature Communications. 10: 4263. PMID 31537790 DOI: 10.1038/S41467-019-12264-9  0.72
2019 Pristerà A, Blomeley C, Lopes E, Threlfell S, Merlini E, Burdakov D, Cragg S, Guillemot F, Ang SL. Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration. Proceedings of the National Academy of Sciences of the United States of America. 116: 3817-3826. PMID 30808767 DOI: 10.1073/Pnas.1806820116  0.64
2018 Brimblecombe KR, Threlfell S, Dautan D, Kosillo P, Mena-Segovia J, Cragg SJ. Targeted Activation of Cholinergic Interneurons Accounts for the Modulation of Dopamine by Striatal Nicotinic Receptors. Eneuro. 5. PMID 30406189 DOI: 10.1523/ENEURO.0397-17.2018  0.72
2016 Kosillo P, Zhang YF, Threlfell S, Cragg SJ. Cortical Control of Striatal Dopamine Transmission via Striatal Cholinergic Interneurons. Cerebral Cortex (New York, N.Y. : 1991). PMID 27566978 DOI: 10.1093/cercor/bhw252  0.72
2016 Sloan M, Alegre-Abarrategui J, Potgieter D, Kaufmann AK, Exley R, Deltheil T, Threlfell S, Connor-Robson N, Brimblecombe K, Wallings R, Cioroch M, Bannerman DM, Bolam JP, Magill PJ, Cragg SJ, et al. LRRK2 BAC transgenic rats develop progressive, L-DOPA-responsive motor impairment, and deficits in dopamine circuit function. Human Molecular Genetics. PMID 26744332 DOI: 10.1093/Hmg/Ddv628  0.64
2015 Pristerà A, Lin W, Kaufmann AK, Brimblecombe KR, Threlfell S, Dodson PD, Magill PJ, Fernandes C, Cragg SJ, Ang SL. Transcription factors FOXA1 and FOXA2 maintain dopaminergic neuronal properties and control feeding behavior in adult mice. Proceedings of the National Academy of Sciences of the United States of America. 112: E4929-38. PMID 26283356 DOI: 10.1073/Pnas.1503911112  1
2015 Padovan-Neto FE, Sammut S, Chakroborty S, Dec AM, Threlfell S, Campbell PW, Mudrakola V, Harms JF, Schmidt CJ, West AR. Facilitation of corticostriatal transmission following pharmacological inhibition of striatal phosphodiesterase 10A: role of nitric oxide-soluble guanylyl cyclase-cGMP signaling pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5781-91. PMID 25855188 DOI: 10.1523/Jneurosci.1238-14.2015  1
2014 Taylor TN, Potgieter D, Anwar S, Senior SL, Janezic S, Threlfell S, Ryan B, Parkkinen L, Deltheil T, Cioroch M, Livieratos A, Oliver PL, Jennings KA, Davies KE, Ansorge O, et al. Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse. Neurobiology of Disease. 62: 193-207. PMID 24121116 DOI: 10.1016/J.Nbd.2013.10.005  1
2014 Threlfell S, West AR. Role of Cyclic Nucleotide Signaling and Phosphodiesterase Activation In The Modulation of Electrophysiological Activity of Central Neurons Cyclic-Nucleotide Phosphodiesterases in the Central Nervous System: From Biology to Drug Discovery. 269-302. DOI: 10.1002/9781118836507.ch11  1
2013 Threlfell S, West AR. Review: Modulation of striatal neuron activity by cyclic nucleotide signaling and phosphodiesterase inhibition. Basal Ganglia. 3: 137-146. PMID 24490129 DOI: 10.1016/j.baga.2013.08.001  1
2013 Janezic S, Threlfell S, Dodson PD, Dowie MJ, Taylor TN, Potgieter D, Parkkinen L, Senior SL, Anwar S, Ryan B, Deltheil T, Kosillo P, Cioroch M, Wagner K, Ansorge O, et al. Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model. Proceedings of the National Academy of Sciences of the United States of America. 110: E4016-25. PMID 24082145 DOI: 10.1073/Pnas.1309143110  1
2012 Threlfell S, Lalic T, Platt NJ, Jennings KA, Deisseroth K, Cragg SJ. Striatal dopamine release is triggered by synchronized activity in cholinergic interneurons. Neuron. 75: 58-64. PMID 22794260 DOI: 10.1016/j.neuron.2012.04.038  1
2011 Anwar S, Peters O, Millership S, Ninkina N, Doig N, Connor-Robson N, Threlfell S, Kooner G, Deacon RM, Bannerman DM, Bolam JP, Chandra SS, Cragg SJ, Wade-Martins R, Buchman VL. Functional alterations to the nigrostriatal system in mice lacking all three members of the synuclein family. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7264-74. PMID 21593311 DOI: 10.1523/Jneurosci.6194-10.2011  1
2011 Hartung H, Threlfell S, Cragg SJ. Nitric oxide donors enhance the frequency dependence of dopamine release in nucleus accumbens. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1811-22. PMID 21508928 DOI: 10.1038/npp.2011.62  1
2011 Exley R, Maubourguet N, David V, Eddine R, Evrard A, Pons S, Marti F, Threlfell S, Cazala P, McIntosh JM, Changeux JP, Maskos U, Cragg SJ, Faure P. Distinct contributions of nicotinic acetylcholine receptor subunit alpha4 and subunit alpha6 to the reinforcing effects of nicotine. Proceedings of the National Academy of Sciences of the United States of America. 108: 7577-82. PMID 21502501 DOI: 10.1073/Pnas.1103000108  1
2011 Threlfell S, Cragg SJ. Dopamine signaling in dorsal versus ventral striatum: the dynamic role of cholinergic interneurons. Frontiers in Systems Neuroscience. 5: 11. PMID 21427783 DOI: 10.3389/fnsys.2011.00011  1
2010 Threlfell S, Clements MA, Khodai T, Pienaar IS, Exley R, Wess J, Cragg SJ. Striatal muscarinic receptors promote activity dependence of dopamine transmission via distinct receptor subtypes on cholinergic interneurons in ventral versus dorsal striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3398-408. PMID 20203199 DOI: 10.1523/JNEUROSCI.5620-09.2010  1
2010 Sammut S, Threlfell S, West AR. Nitric oxide-soluble guanylyl cyclase signaling regulates corticostriatal transmission and short-term synaptic plasticity of striatal projection neurons recorded in vivo. Neuropharmacology. 58: 624-31. PMID 19969007 DOI: 10.1016/j.neuropharm.2009.11.011  1
2010 Threlfell S, Greenfield SA, Cragg SJ. 5-HT(1B) receptor regulation of serotonin (5-HT) release by endogenous 5-HT in the substantia nigra. Neuroscience. 165: 212-20. PMID 19819310 DOI: 10.1016/j.neuroscience.2009.10.005  1
2009 Threlfell S, Sammut S, Menniti FS, Schmidt CJ, West AR. Inhibition of Phosphodiesterase 10A Increases the Responsiveness of Striatal Projection Neurons to Cortical Stimulation. The Journal of Pharmacology and Experimental Therapeutics. 328: 785-95. PMID 19056933 DOI: 10.1124/jpet.108.146332  1
2008 Threlfell S, Exley R, Cragg SJ, Greenfield SA. Constitutive histamine H2 receptor activity regulates serotonin release in the substantia nigra. Journal of Neurochemistry. 107: 745-55. PMID 18761715 DOI: 10.1111/j.1471-4159.2008.05646.x  1
2008 Ondracek JM, Dec A, Hoque KE, Lim SA, Rasouli G, Indorkar RP, Linardakis J, Klika B, Mukherji SJ, Burnazi M, Threlfell S, Sammut S, West AR. Feed-forward excitation of striatal neuron activity by frontal cortical activation of nitric oxide signaling in vivo. The European Journal of Neuroscience. 27: 1739-54. PMID 18371082 DOI: 10.1111/J.1460-9568.2008.06157.X  1
2004 Threlfell S, Cragg SJ, Kalló I, Turi GF, Coen CW, Greenfield SA. Histamine H3 receptors inhibit serotonin release in substantia nigra pars reticulata. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8704-10. PMID 15470136 DOI: 10.1523/JNEUROSCI.2690-04.2004  1
2002 Nekrassova O, White PC, Threlfell S, Hignett G, Wain AJ, Lawrence NS, Davis J, Compton RG. An electrochemical adaptation of Ellman's test. The Analyst. 127: 797-802. PMID 12146914 DOI: 10.1039/b202780c  1
2001 Hignett G, Threlfell S, Wain AJ, Lawrence NS, Wilkins SJ, Davis J, Compton RG, Cardosi MF. Electroanalytical exploitation of quinone-thiol interactions: application to the selective determination of cysteine. The Analyst. 126: 353-7. PMID 11284338 DOI: 10.1039/b008616i  1
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