Jonathan T. Brown - Publications

Affiliations: 
University of Bristol, Bristol, England, United Kingdom 
Area:
Network activity, Intrinsic plasticity

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Smithers HE, Terry JR, Brown JT, Randall AD. Sex-associated differences in excitability within the bed nucleus of the stria terminalis are reflective of cell-type. Neurobiology of Stress. 10: 100143. PMID 30937349 DOI: 10.1016/j.ynstr.2018.100143  0.84
2018 Winter MJ, Windell D, Metz J, Matthews P, Pinion J, Brown JT, Hetheridge MJ, Ball JS, Owen SF, Redfern WS, Moger J, Randall AD, Tyler CR. Author Correction: 4-dimensional functional profiling in the convulsant-treated larval zebrafish brain. Scientific Reports. 8: 15903. PMID 30349014 DOI: 10.1038/s41598-018-32731-5  0.84
2018 Telezhkin V, Straccia M, Yarova P, Pardo M, Yung S, Vinh NN, Hancock JM, Barriga GG, Brown DA, Rosser AE, Brown JT, Canals JM, Randall AD, Allen ND, Kemp PJ. Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons. Pflugers Archiv : European Journal of Physiology. PMID 29797067 DOI: 10.1007/s00424-018-2155-7  0.84
2018 Ridler T, Matthews P, Phillips KG, Randall AD, Brown JT. Initiation and slow propagation of epileptiform activity from ventral to dorsal medial entorhinal cortex is constrained by an inhibitory gradient. The Journal of Physiology. PMID 29604046 DOI: 10.1113/JP275871  0.84
2018 Scullion SE, Barker GRI, Warburton EC, Randall AD, Brown JT. Muscarinic Receptor-Dependent Long Term Depression in the Perirhinal Cortex and Recognition Memory are Impaired in the rTg4510 Mouse Model of Tauopathy. Neurochemical Research. PMID 29484523 DOI: 10.1007/s11064-018-2487-x  0.84
2017 Palombo F, Tamagnini F, Jeynes JCG, Mattana S, Swift I, Nallala J, Hancock J, Brown JT, Randall AD, Stone N. Detection of Aβ plaque-associated astrogliosis in Alzheimer's disease brain by spectroscopic imaging and immunohistochemistry. The Analyst. PMID 29230441 DOI: 10.1039/c7an01747b  0.84
2017 Winter MJ, Windell D, Metz J, Matthews P, Pinion J, Brown JT, Hetheridge MJ, Ball JS, Owen SF, Redfern WS, Moger J, Randall AD, Tyler CR. 4-dimensional functional profiling in the convulsant-treated larval zebrafish brain. Scientific Reports. 7: 6581. PMID 28747660 DOI: 10.1038/s41598-017-06646-6  0.84
2017 Walsh DA, Brown JT, Randall AD. In vitro characterisation of cell-level neurophysiological diversity in the rostral nucleus reuniens of adult mice. The Journal of Physiology. PMID 28295330 DOI: 10.1113/JP273915  0.84
2016 Kemp PJ, Rushton DJ, Yarova PL, Schnell C, Geater C, Hancock JM, Wieland A, Hughes A, Badder L, Cope E, Riccardi D, Randall AD, Brown JT, Allen ND, Telezhkin V. Improving and accelerating the differentiation and functional maturation of human stem cell-derived neurons: role of extracellular calcium and GABA. The Journal of Physiology. PMID 27616476 DOI: 10.1113/JP270655  0.84
2016 Booth CA, Witton J, Nowacki J, Tsaneva-Atanasova K, Jones MW, Randall AD, Brown JT. Altered Intrinsic Pyramidal Neuron Properties and Pathway-Specific Synaptic Dysfunction Underlie Aberrant Hippocampal Network Function in a Mouse Model of Tauopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 350-63. PMID 26758828 DOI: 10.1523/JNEUROSCI.2151-15.2016  0.88
2016 Booth CA, Ridler T, Murray TK, Ward MA, de Groot E, Goodfellow M, Phillips KG, Randall AD, Brown JT. Electrical and Network Neuronal Properties Are Preferentially Disrupted in Dorsal, But Not Ventral, Medial Entorhinal Cortex in a Mouse Model of Tauopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 312-24. PMID 26758825 DOI: 10.1523/JNEUROSCI.2845-14.2016  0.88
2015 Telezhkin V, Schnell C, Yarova PL, Yung S, Sanders P, Cope E, Hughes A, Thompson BA, Geater C, Hancock JM, Joy S, Badder L, Connor-Robson N, Comella A, Straccia M, ... ... Brown JT, et al. Forced cell-cycle exit and modulation of GABAA, CREB and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons. American Journal of Physiology. Cell Physiology. ajpcell.00166.2015. PMID 26718628 DOI: 10.1152/ajpcell.00166.2015  0.88
2015 Tamagnini F, Novelia J, Kerrigan TL, Brown JT, Tsaneva-Atanasova K, Randall AD. Altered intrinsic excitability of hippocampal CA1 pyramidal neurons in aged PDAPP mice. Frontiers in Cellular Neuroscience. 9: 372. PMID 26528126 DOI: 10.3389/fncel.2015.00372  0.88
2015 Banks PJ, Burroughs AC, Barker GR, Brown JT, Warburton EC, Bashir ZI. Disruption of hippocampal-prefrontal cortex activity by dopamine D2R-dependent LTD of NMDAR transmission. Proceedings of the National Academy of Sciences of the United States of America. PMID 26286993 DOI: 10.1073/pnas.1512064112  0.88
2015 Witton J, Padmashri R, Zinyuk LE, Popov VI, Kraev I, Line SJ, Jensen TP, Tedoldi A, Cummings DM, Tybulewicz VL, Fisher EM, Bannerman DM, Randall AD, Brown JT, Edwards FA, et al. Hippocampal circuit dysfunction in the Tc1 mouse model of Down syndrome. Nature Neuroscience. 18: 1291-8. PMID 26237367 DOI: 10.1038/nn.4072  0.84
2015 Dawson N, Kurihara M, Thomson DM, Winchester CL, McVie A, Hedde JR, Randall AD, Shen S, Seymour PA, Hughes ZA, Dunlop J, Brown JT, Brandon NJ, Morris BJ, Pratt JA. Altered functional brain network connectivity and glutamate system function in transgenic mice expressing truncated Disrupted-in-Schizophrenia 1. Translational Psychiatry. 5: e569. PMID 25989143 DOI: 10.1038/tp.2015.60  0.84
2015 Martin HG, Lassalle O, Brown JT, Manzoni OJ. Age-Dependent Long-Term Potentiation Deficits in the Prefrontal Cortex of the Fmr1 Knockout Mouse Model of Fragile X Syndrome. Cerebral Cortex (New York, N.Y. : 1991). PMID 25750254 DOI: 10.1093/cercor/bhv031  0.88
2015 Tamagnini F, Scullion S, Brown JT, Randall AD. Intrinsic excitability changes induced by acute treatment of hippocampal CA1 pyramidal neurons with exogenous amyloid β peptide. Hippocampus. 25: 786-97. PMID 25515596 DOI: 10.1002/hipo.22403  0.88
2015 Church TW, Weatherall KL, Corrêa SA, Prole DL, Brown JT, Marrion NV. Preferential assembly of heteromeric small conductance calcium-activated potassium channels. The European Journal of Neuroscience. 41: 305-15. PMID 25421315 DOI: 10.1111/ejn.12789  0.88
2015 Witton J, Padmashri R, Zinyuk LE, Popov VI, Kraev I, Line SJ, Jensen TP, Tedoldi A, Cummings DM, Tybulewicz VLJ, Fisher EMC, Bannerman DM, Randall AD, Brown JT, Edwards FA, et al. Hippocampal circuit dysfunction in the Tc1 mouse model of Down syndrome Nature Neuroscience. DOI: 10.1038/nn.4072  0.88
2014 Witton J, Staniaszek LE, Bartsch U, Randall AD, Jones MW, Brown JT. Disrupted hippocampal sharp-wave ripple-associated spike dynamics in a transgenic mouse model of dementia. The Journal of Physiology. PMID 25480798 DOI: 10.1113/jphysiol.2014.282889  0.88
2014 Booth CA, Brown JT, Randall AD. Neurophysiological modification of CA1 pyramidal neurons in a transgenic mouse expressing a truncated form of disrupted-in-schizophrenia 1. The European Journal of Neuroscience. 39: 1074-90. PMID 24712988 DOI: 10.1111/ejn.12549  0.88
2014 Randall AD, Kurihara M, Brandon NJ, Brown JT. Disrupted in schizophrenia 1 and synaptic function in the mammalian central nervous system. The European Journal of Neuroscience. 39: 1068-73. PMID 24712987 DOI: 10.1111/ejn.12500  0.88
2014 Tamagnini F, Scullion S, Brown JT, Randall AD. Low concentrations of the solvent dimethyl sulphoxide alter intrinsic excitability properties of cortical and hippocampal pyramidal cells. Plos One. 9: e92557. PMID 24647720 DOI: 10.1371/journal.pone.0092557  0.88
2014 Kerrigan TL, Brown JT, Randall AD. Characterization of altered intrinsic excitability in hippocampal CA1 pyramidal cells of the Aβ-overproducing PDAPP mouse. Neuropharmacology. 79: 515-24. PMID 24055500 DOI: 10.1016/j.neuropharm.2013.09.004  0.88
2013 Corbett BF, Leiser SC, Ling HP, Nagy R, Breysse N, Zhang X, Hazra A, Brown JT, Randall AD, Wood A, Pangalos MN, Reinhart PH, Chin J. Sodium channel cleavage is associated with aberrant neuronal activity and cognitive deficits in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 7020-6. PMID 23595759 DOI: 10.1523/JNEUROSCI.2325-12.2013  0.48
2013 Brown J, Hainsworth AH, Stefani A, Randall AD. Whole-cell patch-clamp recording of voltage-sensitive Ca²⁺ channel currents in single cells: heterologous expression systems and neurones. Methods in Molecular Biology (Clifton, N.J.). 937: 123-48. PMID 23007583 DOI: 10.1007/978-1-62703-086-1_7  0.88
2013 Brown J, Hainsworth AH, Stefani A, Randall AD. Whole-cell patch-clamp recording of voltage-sensitive Ca2+ channel currents in single cells: Heterologous expression systems and neurones Methods in Molecular Biology. 937: 123-148. DOI: 10.1007/978-1-62703-86-1_7  0.88
2012 Forsyth LH, Witton J, Brown JT, Randall AD, Jones MW. In Vitro and In Vivo Recording of Local Field Potential Oscillations in Mouse Hippocampus. Current Protocols in Mouse Biology. 2: 273-94. PMID 26069015 DOI: 10.1002/9780470942390.mo120089  0.84
2012 Randall AD, Booth C, Brown JT. Age-related changes to Na+ channel gating contribute to modified intrinsic neuronal excitability. Neurobiology of Aging. 33: 2715-20. PMID 22284989 DOI: 10.1016/j.neurobiolaging.2011.12.030  0.88
2011 Sitzia F, Brown JT, Randall AD, Dunlop J. Voltage- and Temperature-Dependent Allosteric Modulation of α7 Nicotinic Receptors by PNU120596. Frontiers in Pharmacology. 2: 81. PMID 22207849 DOI: 10.3389/fphar.2011.00081  0.88
2011 McMillan LE, Brown JT, Henley JM, Cimarosti H. Profiles of SUMO and ubiquitin conjugation in an Alzheimer's disease model. Neuroscience Letters. 502: 201-8. PMID 21843595 DOI: 10.1016/j.neulet.2011.07.045  0.88
2011 Brown JT, Chin J, Leiser SC, Pangalos MN, Randall AD. Altered intrinsic neuronal excitability and reduced Na+ currents in a mouse model of Alzheimer's disease. Neurobiology of Aging. 32: 2109.e1-14. PMID 21794952 DOI: 10.1016/j.neurobiolaging.2011.05.025  0.88
2011 Brown JT, Booth CA, Randall AD. Synaptic activation of mGluR1 generates persistent depression of a fast after-depolarizing potential in CA3 pyramidal neurons. The European Journal of Neuroscience. 33: 879-89. PMID 21269340 DOI: 10.1111/j.1460-9568.2010.07565.x  0.88
2011 Nowacki J, Osinga HM, Brown JT, Randall AD, Tsaneva-Atanasova K. A unified model of CA1/3 pyramidal cells: an investigation into excitability. Progress in Biophysics and Molecular Biology. 105: 34-48. PMID 20887748 DOI: 10.1016/j.pbiomolbio.2010.09.020  0.88
2010 Brown JT, Weatherall KL, Corria LR, Chater TE, Isaac JT, Marrion NV. Vesicular release of glutamate utilizes the proton gradient between the vesicle and synaptic cleft. Frontiers in Synaptic Neuroscience. 2: 15. PMID 21423501 DOI: 10.3389/fnsyn.2010.00015  0.88
2010 Witton J, Brown JT, Jones MW, Randall AD. Altered synaptic plasticity in the mossy fibre pathway of transgenic mice expressing mutant amyloid precursor protein. Molecular Brain. 3: 32. PMID 21040543 DOI: 10.1186/1756-6606-3-32  0.88
2010 Chater TE, Henley JM, Brown JT, Randall AD. Voltage- and temperature-dependent gating of heterologously expressed channelrhodopsin-2. Journal of Neuroscience Methods. 193: 7-13. PMID 20691205 DOI: 10.1016/j.jneumeth.2010.07.033  0.88
2010 Randall AD, Witton J, Booth C, Hynes-Allen A, Brown JT. The functional neurophysiology of the amyloid precursor protein (APP) processing pathway. Neuropharmacology. 59: 243-67. PMID 20167227 DOI: 10.1016/j.neuropharm.2010.02.011  0.88
2009 Di Sabatino A, Rovedatti L, Kaur R, Spencer JP, Brown JT, Morisset VD, Biancheri P, Leakey NA, Wilde JI, Scott L, Corazza GR, Lee K, Sengupta N, Knowles CH, Gunthorpe MJ, et al. Targeting gut T cell Ca2+ release-activated Ca2+ channels inhibits T cell cytokine production and T-box transcription factor T-bet in inflammatory bowel disease. Journal of Immunology (Baltimore, Md. : 1950). 183: 3454-62. PMID 19648266 DOI: 10.4049/jimmunol.0802887  0.88
2009 Clement JP, Randall AD, Brown JT. Metabotropic glutamate receptor 1 activity generates persistent, N-methyl-D-aspartate receptor-dependent depression of hippocampal pyramidal cell excitability. The European Journal of Neuroscience. 29: 2347-62. PMID 19490024 DOI: 10.1111/j.1460-9568.2009.06780.x  0.88
2009 Brown JT, Randall AD. Activity-dependent depression of the spike after-depolarization generates long-lasting intrinsic plasticity in hippocampal CA3 pyramidal neurons. The Journal of Physiology. 587: 1265-81. PMID 19171653 DOI: 10.1113/jphysiol.2008.167007  0.88
2009 Dunlop J, Lock T, Jow B, Sitzia F, Grauer S, Jow F, Kramer A, Bowlby MR, Randall A, Kowal D, Gilbert A, Comery TA, Larocque J, Soloveva V, Brown J, et al. Old and new pharmacology: positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor by the 5-hydroxytryptamine(2B/C) receptor antagonist SB-206553 (3,5-dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']di pyrrole-1(2H)-carboxamide). The Journal of Pharmacology and Experimental Therapeutics. 328: 766-76. PMID 19050173 DOI: 10.1124/jpet.108.146514  0.88
2008 Piccinin S, Thuault SJ, Doherty AJ, Brown JT, Randall AD, Davies CH, Bortolotto ZA, Collingridge GL. The induction of long-term plasticity of non-synaptic, synchronized activity by the activation of group I mGluRs. Neuropharmacology. 55: 459-63. PMID 18619627 DOI: 10.1016/j.neuropharm.2008.05.017  0.88
2008 Langmead CJ, Austin NE, Branch CL, Brown JT, Buchanan KA, Davies CH, Forbes IT, Fry VA, Hagan JJ, Herdon HJ, Jones GA, Jeggo R, Kew JN, Mazzali A, Melarange R, et al. Characterization of a CNS penetrant, selective M1 muscarinic receptor agonist, 77-LH-28-1. British Journal of Pharmacology. 154: 1104-15. PMID 18454168 DOI: 10.1038/bjp.2008.152  0.68
2007 Brown JT, Davies CH, Randall AD. Synaptic activation of GABA(B) receptors regulates neuronal network activity and entrainment. The European Journal of Neuroscience. 25: 2982-90. PMID 17561812 DOI: 10.1111/j.1460-9568.2007.05544.x  0.88
2006 Teriakidis A, Brown JT, Randall A. Frequency-dependent inhibition of antidromic hippocampal compound action potentials by anti-convulsants. Pharmacological Reports : Pr. 58: 859-69. PMID 17220543  0.88
2006 Fonfria E, Mattei C, Hill K, Brown JT, Randall A, Benham CD, Skaper SD, Campbell CA, Crook B, Murdock PR, Wilson JM, Maurio FP, Owen DE, Tilling PL, McNulty S. TRPM2 is elevated in the tMCAO stroke model, transcriptionally regulated, and functionally expressed in C13 microglia. Journal of Receptor and Signal Transduction Research. 26: 179-98. PMID 16777714 DOI: 10.1080/10799890600637522  0.68
2006 Piccinin S, Randall AD, Brown JT. KCNQ/Kv7 channel regulation of hippocampal gamma-frequency firing in the absence of synaptic transmission. Journal of Neurophysiology. 95: 3105-12. PMID 16467425 DOI: 10.1152/jn.01083.2005  0.68
2006 Gill CH, Brown JT, Shivji N, Lappin SC, Farmer C, Randall A, McNaughton NC, Cobb SR, Davies CH. Inhibition of Ih reduces epileptiform activity in rodent hippocampal slices. Synapse (New York, N.Y.). 59: 308-16. PMID 16421904 DOI: 10.1002/syn.20242  0.88
2006 Brown JT, Teriakidis A, Randall AD. A pharmacological investigation of the role of GLUK5-containing receptors in kainate-driven hippocampal gamma band oscillations. Neuropharmacology. 50: 47-56. PMID 16153668 DOI: 10.1016/j.neuropharm.2005.07.017  0.88
2005 Lappin SC, Dale TJ, Brown JT, Trezise DJ, Davies CH. Activation of SK channels inhibits epileptiform bursting in hippocampal CA3 neurons. Brain Research. 1065: 37-46. PMID 16336949 DOI: 10.1016/j.brainres.2005.10.024  0.88
2005 Thuault SJ, Brown JT, Calver AR, Collingridge GL, Randall A, Davies CH. Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices expressing a C-terminal truncated GABA(B2) receptor subunit. Epilepsy Research. 65: 41-51. PMID 15979855 DOI: 10.1016/j.eplepsyres.2005.04.004  0.88
2005 Brown JT, Randall A. Gabapentin fails to alter P/Q-type Ca2+ channel-mediated synaptic transmission in the hippocampus in vitro. Synapse (New York, N.Y.). 55: 262-9. PMID 15668986 DOI: 10.1002/syn.20115  0.88
2005 Brown JT, Richardson JC, Collingridge GL, Randall AD, Davies CH. Synaptic transmission and synchronous activity is disrupted in hippocampal slices taken from aged TAS10 mice. Hippocampus. 15: 110-7. PMID 15390159 DOI: 10.1002/hipo.20036  0.68
2004 Spencer JP, Brown JT, Richardson JC, Medhurst AD, Sehmi SS, Calver AR, Randall AD. Modulation of hippocampal excitability by 5-HT4 receptor agonists persists in a transgenic model of Alzheimer's disease. Neuroscience. 129: 49-54. PMID 15489027 DOI: 10.1016/j.neuroscience.2004.06.070  0.88
2004 Thuault SJ, Brown JT, Sheardown SA, Jourdain S, Fairfax B, Spencer JP, Restituito S, Nation JH, Topps S, Medhurst AD, Randall AD, Couve A, Moss SJ, Collingridge GL, Pangalos MN, et al. The GABA(B2) subunit is critical for the trafficking and function of native GABA(B) receptors. Biochemical Pharmacology. 68: 1655-66. PMID 15451409 DOI: 10.1016/j.bcp.2004.07.032  0.88
2003 Brown JT, Gill CH, Farmer CE, Lanneau C, Randall AD, Pangalos MN, Collingridge GL, Davies CH. Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices of GABAB1 receptor subunit knockout mice. Epilepsy Research. 57: 121-36. PMID 15013053 DOI: 10.1016/j.eplepsyres.2003.10.013  0.88
2003 Harrison SM, Reavill C, Brown G, Brown JT, Cluderay JE, Crook B, Davies CH, Dawson LA, Grau E, Heidbreder C, Hemmati P, Hervieu G, Howarth A, Hughes ZA, Hunter AJ, et al. LPA1 receptor-deficient mice have phenotypic changes observed in psychiatric disease. Molecular and Cellular Neurosciences. 24: 1170-9. PMID 14697676 DOI: 10.1016/j.mcn.2003.09.001  0.88
2001 Lanneau C, Green A, Hirst WD, Wise A, Brown JT, Donnier E, Charles KJ, Wood M, Davies CH, Pangalos MN. Gabapentin is not a GABAB receptor agonist. Neuropharmacology. 41: 965-75. PMID 11747901 DOI: 10.1016/S0028-3908(01)00140-X  0.88
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