Amir S. Khan, Ph.D. - Publications

Affiliations: 
Wake Forest University School of Medicine, Winston-Salem, NC, United States 
Area:
brain aging

89 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Trimble CL, Morrow MP, Kraynyak KA, Shen X, Dallas M, Yan J, Edwards L, Parker RL, Denny L, Giffear M, Brown AS, Marcozzi-Pierce K, Shah D, Slager AM, Sylvester AJ, ... Khan A, et al. Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b trial. Lancet (London, England). PMID 26386540 DOI: 10.1016/S0140-6736(15)00239-1  0.4
2015 Muthumani K, Falzarano D, Reuschel EL, Tingey C, Flingai S, Villarreal DO, Wise M, Patel A, Izmirly A, Aljuaid A, Seliga AM, Soule G, Morrow M, Kraynyak KA, Khan AS, et al. A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates. Science Translational Medicine. 7: 301ra132. PMID 26290414 DOI: 10.1126/scitranslmed.aac7462  0.4
2015 Amante DH, Smith TR, Mendoza JM, Schultheis K, McCoy JB, Khan A, Sardesai NY, Broderick KE. Skin transfection patterns and expression kinetics of EP-enhanced plasmid delivery using the CELLECTRA®-3P, a portable next generation dermal electroporation device. Human Gene Therapy Methods. PMID 26222896 DOI: 10.1089/hgtb.2015.020  0.4
2015 Wise MC, Hutnick NA, Pollara J, Myles DJ, Williams C, Yan J, LaBranche CC, Khan AS, Sardesai NY, Montefiori D, Barnett SW, Zolla-Pazner S, Ferrari G, Weiner DB. An enhanced synthetic multi-clade DNA prime induces improved cross-clade reactive functional antibodies when combined with an adjuvanted protein boost in non-human primates. Journal of Virology. PMID 26085155 DOI: 10.1128/JVI.00652-15  0.4
2015 Morrow MP, Tebas P, Yan J, Ramirez L, Slager A, Kraynyak K, Diehl M, Shah D, Khan A, Lee J, Boyer J, Kim JJ, Sardesai NY, Weiner DB, Bagarazzi ML. Synthetic consensus HIV-1 DNA induces potent cellular immune responses and synthesis of granzyme B, perforin in HIV infected individuals. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 591-601. PMID 25531694 DOI: 10.1038/mt.2014.245  0.4
2014 Latimer B, Toporovski R, Yan J, Pankhong P, Morrow MP, Khan AS, Sardesai NY, Welles SL, Jacobson JM, Weiner DB, Kutzler MA. Strong HCV NS3/4a, NS4b, NS5a, NS5b-specific cellular immune responses induced in Rhesus macaques by a novel HCV genotype 1a/1b consensus DNA vaccine. Human Vaccines & Immunotherapeutics. 10: 2357-65. PMID 25424943 DOI: 10.4161/hv.29590  0.4
2014 Baliban SM, Michael A, Shammassian B, Mudakha S, Khan AS, Cocklin S, Zentner I, Latimer BP, Bouillaut L, Hunter M, Marx P, Sardesai NY, Welles SL, Jacobson JM, Weiner DB, et al. An optimized, synthetic DNA vaccine encoding the toxin A and toxin B receptor binding domains of Clostridium difficile induces protective antibody responses in vivo. Infection and Immunity. 82: 4080-91. PMID 25024365 DOI: 10.1128/IAI.01950-14  0.4
2014 Broderick KE, Khan AS, Sardesai NY. DNA vaccination in skin enhanced by electroporation. Methods in Molecular Biology (Clifton, N.J.). 1143: 123-30. PMID 24715285 DOI: 10.1007/978-1-4939-0410-5_8  0.4
2014 Yan J, Villarreal DO, Racine T, Chu JS, Walters JN, Morrow MP, Khan AS, Sardesai NY, Kim JJ, Kobinger GP, Weiner DB. Protective immunity to H7N9 influenza viruses elicited by synthetic DNA vaccine. Vaccine. 32: 2833-42. PMID 24631084 DOI: 10.1016/j.vaccine.2014.02.038  0.4
2014 Khan AS, Broderick KE, Sardesai NY. Clinical development of intramuscular electroporation: providing a "boost" for DNA vaccines. Methods in Molecular Biology (Clifton, N.J.). 1121: 279-89. PMID 24510832 DOI: 10.1007/978-1-4614-9632-8_25  0.4
2013 Yan J, Pankhong P, Shin TH, Obeng-Adjei N, Morrow MP, Walters JN, Khan AS, Sardesai NY, Weiner DB. Highly optimized DNA vaccine targeting human telomerase reverse transcriptase stimulates potent antitumor immunity. Cancer Immunology Research. 1: 179-89. PMID 24777680 DOI: 10.1158/2326-6066.CIR-13-0001  0.4
2013 Diehl MC, Lee JC, Daniels SE, Tebas P, Khan AS, Giffear M, Sardesai NY, Bagarazzi ML. Tolerability of intramuscular and intradermal delivery by CELLECTRA(®) adaptive constant current electroporation device in healthy volunteers. Human Vaccines & Immunotherapeutics. 9: 2246-52. PMID 24051434 DOI: 10.4161/hv.24702  0.4
2013 Ferraro B, Talbott KT, Balakrishnan A, Cisper N, Morrow MP, Hutnick NA, Myles DJ, Shedlock DJ, Obeng-Adjei N, Yan J, Kayatani AK, Richie N, Cabrera W, Shiver R, Khan AS, et al. Inducing humoral and cellular responses to multiple sporozoite and liver-stage malaria antigens using exogenous plasmid DNA. Infection and Immunity. 81: 3709-20. PMID 23897618 DOI: 10.1128/IAI.00180-13  0.4
2013 Kalams SA, Parker SD, Elizaga M, Metch B, Edupuganti S, Hural J, De Rosa S, Carter DK, Rybczyk K, Frank I, Fuchs J, Koblin B, Kim DH, Joseph P, Keefer MC, ... ... Khan AS, et al. Safety and comparative immunogenicity of an HIV-1 DNA vaccine in combination with plasmid interleukin 12 and impact of intramuscular electroporation for delivery. The Journal of Infectious Diseases. 208: 818-29. PMID 23840043 DOI: 10.1093/infdis/jit236  0.4
2012 Broderick KE, Chan A, Lin F, Shen X, Kichaev G, Khan AS, Aubin J, Zimmermann TS, Sardesai NY. Optimized in vivo transfer of small interfering RNA targeting dermal tissue using in vivo surface electroporation. Molecular Therapy. Nucleic Acids. 1: e11. PMID 23344722 DOI: 10.1038/mtna.2012.1  0.4
2012 Bagarazzi ML, Yan J, Morrow MP, Shen X, Parker RL, Lee JC, Giffear M, Pankhong P, Khan AS, Broderick KE, Knott C, Lin F, Boyer JD, Draghia-Akli R, White CJ, et al. Immunotherapy against HPV16/18 generates potent TH1 and cytotoxic cellular immune responses. Science Translational Medicine. 4: 155ra138. PMID 23052295 DOI: 10.1126/scitranslmed.3004414  0.4
2012 Brown PA, Khan AS, Draghia-Akli R, Pope MA, Bodles-Brakhop AM, Kern DR. Effects of administration of two growth hormone-releasing hormone plasmids to gilts on sow and litter performance for the subsequent three gestations American Journal of Veterinary Research. 73: 1428-1434. PMID 22924725 DOI: 10.2460/ajvr.73.9.1428  0.4
2012 Lin F, Shen X, Kichaev G, Mendoza JM, Yang M, Armendi P, Yan J, Kobinger GP, Bello A, Khan AS, Broderick KE, Sardesai NY. Optimization of electroporation-enhanced intradermal delivery of DNA vaccine using a minimally invasive surface device. Human Gene Therapy Methods. 23: 157-68. PMID 22794496 DOI: 10.1089/hgtb.2011.209  0.4
2012 Yin J, Vahey MT, Dai A, Lewis MG, Arango T, Yalley-Ogunro J, Greenhouse J, Mendoza K, Khan A, Sardesai NY, Weiss W, Komisar J, Boyer JD. Plasmodium inui infection reduces the efficacy of a simian immunodeficiency virus DNA vaccine in a rhesus macaque model through alteration of the vaccine-induced immune response. The Journal of Infectious Diseases. 206: 523-33. PMID 22693228 DOI: 10.1093/infdis/jis404  0.4
2012 Hutnick NA, Myles DJ, Ferraro B, Lucke C, Lin F, Yan J, Broderick KE, Khan AS, Sardesai NY, Weiner DB. Intradermal DNA vaccination enhanced by low-current electroporation improves antigen expression and induces robust cellular and humoral immune responses. Human Gene Therapy. 23: 943-50. PMID 22650607 DOI: 10.1089/hum.2012.055  0.4
2012 Hutnick NA, Myles DJ, Hirao L, Scott VL, Ferraro B, Khan AS, Lewis MG, Miller CJ, Bett AJ, Casimiro D, Sardesai NY, Kim JJ, Shiver J, Weiner DB. An optimized SIV DNA vaccine can serve as a boost for Ad5 and provide partial protection from a high-dose SIVmac251 challenge. Vaccine. 30: 3202-8. PMID 22406458 DOI: 10.1016/j.vaccine.2012.02.069  0.4
2012 Shin TH, Pankhong P, Yan J, Khan AS, Sardesai NY, Weiner DB. Induction of robust cellular immunity against HPV6 and HPV11 in mice by DNA vaccine encoding for E6/E7 antigen. Human Vaccines & Immunotherapeutics. 8: 470-8. PMID 22336879 DOI: 10.4161/hv.19180  0.4
2012 Lang Kuhs KA, Ginsberg AA, Yan J, Wiseman RW, Khan AS, Sardesai NY, O'Connor DH, Weiner DB. Hepatitis C virus NS3/NS4A DNA vaccine induces multiepitope T cell responses in rhesus macaques mimicking human immune responses [corrected]. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 669-78. PMID 21952169 DOI: 10.1038/mt.2011.188  0.4
2011 Belisle SE, Yin J, Shedlock DJ, Dai A, Yan J, Hirao L, Kutzler MA, Lewis MG, Andersen H, Lank SM, Karl JA, O'Connor DH, Khan A, Sardesai N, Chang J, et al. Long-term programming of antigen-specific immunity from gene expression signatures in the PBMC of rhesus macaques immunized with an SIV DNA vaccine. Plos One. 6: e19681. PMID 21701683 DOI: 10.1371/journal.pone.0019681  0.4
2011 Yan J, Corbitt N, Pankhong P, Shin T, Khan A, Sardesai NY, Weiner DB. Immunogenicity of a novel engineered HIV-1 clade C synthetic consensus-based envelope DNA vaccine. Vaccine. 29: 7173-81. PMID 21651948 DOI: 10.1016/j.vaccine.2011.05.076  0.4
2011 Ferraro B, Cisper NJ, Talbott KT, Philipson-Weiner L, Lucke CE, Khan AS, Sardesai NY, Weiner DB. Co-delivery of PSA and PSMA DNA vaccines with electroporation induces potent immune responses. Human Vaccines. 7: 120-7. PMID 21266849 DOI: 10.4161/hv.7.0.14574  0.4
2011 Mallilankaraman K, Shedlock DJ, Bao H, Kawalekar OU, Fagone P, Ramanathan AA, Ferraro B, Stabenow J, Vijayachari P, Sundaram SG, Muruganandam N, Sarangan G, Srikanth P, Khan AS, Lewis MG, et al. A DNA vaccine against chikungunya virus is protective in mice and induces neutralizing antibodies in mice and nonhuman primates. Plos Neglected Tropical Diseases. 5: e928. PMID 21264351 DOI: 10.1371/journal.pntd.0000928  0.4
2011 Shedlock DJ, Talbott KT, Cress C, Ferraro B, Tuyishme S, Mallilankaraman K, Cisper NJ, Morrow MP, Wu SJ, Kawalekar OU, Khan AS, Sardesai NY, Muthumani K, Shen H, Weiner DB. A highly optimized DNA vaccine confers complete protective immunity against high-dose lethal lymphocytic choriomeningitis virus challenge. Vaccine. 29: 6755-62. PMID 21238574 DOI: 10.1016/j.vaccine.2010.12.064  0.4
2011 Lin F, Shen X, McCoy JR, Mendoza JM, Yan J, Kemmerrer SV, Khan AS, Weiner DB, Broderick KE, Sardesai NY. A novel prototype device for electroporation-enhanced DNA vaccine delivery simultaneously to both skin and muscle. Vaccine. 29: 6771-80. PMID 21199706 DOI: 10.1016/j.vaccine.2010.12.057  0.4
2011 Yin J, Dai A, Lecureux J, Arango T, Kutzler MA, Yan J, Lewis MG, Khan A, Sardesai NY, Montefiore D, Ruprecht R, Weiner DB, Boyer JD. High antibody and cellular responses induced to HIV-1 clade C envelope following DNA vaccines delivered by electroporation. Vaccine. 29: 6763-70. PMID 21195801 DOI: 10.1016/j.vaccine.2010.12.055  0.4
2011 Bodles-Brakhop AM, Draghia-Akli R, Broderick K, Khan AS. Electroporation of plasmid DNA to swine muscle. Methods in Molecular Biology (Clifton, N.J.). 709: 257-64. PMID 21194033 DOI: 10.1007/978-1-61737-982-6_16  0.4
2011 Hirao LA, Draghia-Akli R, Prigge JT, Yang M, Satishchandran A, Wu L, Hammarlund E, Khan AS, Babas T, Rhodes L, Silvera P, Slifka M, Sardesai NY, Weiner DB. Multivalent smallpox DNA vaccine delivered by intradermal electroporation drives protective immunity in nonhuman primates against lethal monkeypox challenge. The Journal of Infectious Diseases. 203: 95-102. PMID 21148501 DOI: 10.1093/infdis/jiq017  0.4
2011 Broderick KE, Shen X, Soderholm J, Lin F, McCoy J, Khan AS, Yan J, Morrow MP, Patel A, Kobinger GP, Kemmerrer S, Weiner DB, Sardesai NY. Prototype development and preclinical immunogenicity analysis of a novel minimally invasive electroporation device. Gene Therapy. 18: 258-65. PMID 20962869 DOI: 10.1038/gt.2010.137  0.4
2010 Morrow MP, Yan J, Pankhong P, Ferraro B, Lewis MG, Khan AS, Sardesai NY, Weiner DB. Unique Th1/Th2 phenotypes induced during priming and memory phases by use of interleukin-12 (IL-12) or IL-28B vaccine adjuvants in rhesus macaques. Clinical and Vaccine Immunology : Cvi. 17: 1493-9. PMID 20685940 DOI: 10.1128/CVI.00181-10  0.4
2010 Morrow MP, Yan J, Pankhong P, Shedlock DJ, Lewis MG, Talbott K, Toporovski R, Khan AS, Sardesai NY, Weiner DB. IL-28B/IFN-lambda 3 drives granzyme B loading and significantly increases CTL killing activity in macaques. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1714-23. PMID 20571540 DOI: 10.1038/mt.2010.118  0.4
2010 Hirao LA, Wu L, Satishchandran A, Khan AS, Draghia-Akli R, Finnefrock AC, Bett AJ, Betts MR, Casimiro DR, Sardesai NY, Kim JJ, Shiver JW, Weiner DB. Comparative analysis of immune responses induced by vaccination with SIV antigens by recombinant Ad5 vector or plasmid DNA in rhesus macaques. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1568-76. PMID 20551910 DOI: 10.1038/mt.2010.112  0.4
2010 Thiboutot MM, Kannan S, Kawalekar OU, Shedlock DJ, Khan AS, Sarangan G, Srikanth P, Weiner DB, Muthumani K. Chikungunya: a potentially emerging epidemic? Plos Neglected Tropical Diseases. 4: e623. PMID 20436958 DOI: 10.1371/journal.pntd.0000623  0.4
2010 Valentin A, von Gegerfelt A, Rosati M, Miteloudis G, Alicea C, Bergamaschi C, Jalah R, Patel V, Khan AS, Draghia-Akli R, Pavlakis GN, Felber BK. Repeated DNA therapeutic vaccination of chronically SIV-infected macaques provides additional virological benefit. Vaccine. 28: 1962-74. PMID 20188252 DOI: 10.1016/j.vaccine.2009.10.099  0.4
2010 Kraynyak KA, Kutzler MA, Cisper NJ, Khan AS, Draghia-Akli R, Sardesal NY, Lewis MG, Yan J, Weiner DB. Systemic immunization with CCL27/CTACK modulates immune responses at mucosal sites in mice and macaques. Vaccine. 28: 1942-51. PMID 20188250 DOI: 10.1016/j.vaccine.2009.10.095  0.4
2010 Khan AS, Bodles-Brakhop AM, Fiorotto ML, Draghia-Akli R. Effects of maternal plasmid GHRH treatment on offspring growth. Vaccine. 28: 1905-10. PMID 20188245 DOI: 10.1016/j.vaccine.2009.10.093  0.4
2010 Khan AS, Draghia-Akli R, Shypailo RJ, Ellis KI, Mersmann H, Fiorotto ML. A comparison of the growth responses following intramuscular GHRH plasmid administration versus daily growth hormone injections in young pigs. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 327-33. PMID 19809401 DOI: 10.1038/mt.2009.224  0.4
2009 Rosati M, Bergamaschi C, Valentin A, Kulkarni V, Jalah R, Alicea C, Patel V, von Gegerfelt AS, Montefiori DC, Venzon DJ, Khan AS, Draghia-Akli R, Van Rompay KK, Felber BK, Pavlakis GN. DNA vaccination in rhesus macaques induces potent immune responses and decreases acute and chronic viremia after SIVmac251 challenge. Proceedings of the National Academy of Sciences of the United States of America. 106: 15831-6. PMID 19717425 DOI: 10.1073/pnas.0902628106  0.4
2009 Yin J, Dai A, Laddy DJ, Yan J, Arango T, Khan AS, Lewis MG, Andersen H, Kutzler MA, Draghia-Akli R, Weiner DB, Boyer JD. High dose of plasmid IL-15 inhibits immune responses in an influenza non-human primates immunogenicity model. Virology. 393: 49-55. PMID 19683780 DOI: 10.1016/j.virol.2009.07.017  0.4
2009 Laddy DJ, Yan J, Khan AS, Andersen H, Cohn A, Greenhouse J, Lewis M, Manischewitz J, King LR, Golding H, Draghia-Akli R, Weiner DB. Electroporation of synthetic DNA antigens offers protection in nonhuman primates challenged with highly pathogenic avian influenza virus. Journal of Virology. 83: 4624-30. PMID 19211745 DOI: 10.1128/JVI.02335-08  0.4
2009 Kraynyak KA, Kutzler MA, Pahar B, Sylvester A, Yan J, Carnathan D, Khan AS, Sardesai N, Moldoveanu Z, Mestecky J, Betts MR, Marx P, Weiner DB. P19-46. Co-delivery of mucosal chemokine plasmids in a systemically delivered DNA vaccine elicits systemic and mucosal immune responses in mice and macaques Retrovirology. 6: P366. DOI: 10.1186/1742-4690-6-S3-P366  0.4
2009 Felber BK, Valentin A, von Gegerfelt A, Jalah R, Patel V, Kulkarni V, Alicea C, Rosati M, Khan A, Draghia-Akli R, Pavlakis GN. P18-09. Persistent virological benefit in SIV-infected macaques upon therapeutic vaccination upon vaccination with DNA vectors Retrovirology. 6: P318. DOI: 10.1186/1742-4690-6-S3-P318  0.4
2009 Pavlakis GN, Rosati M, Patel V, Valentin A, Bergamaschi C, Kulkarni V, Jalah R, von Gegerfelt A, Ohlen C, Khan A, Draghia-Akli R, Van Rompay K, Felber BK. P14-08. Intramuscular DNA delivery by electroporation leads to greatly enhanced systemic and mucosal immune responses and control of SIVmac251 challenge Retrovirology. 6: P196. DOI: 10.1186/1742-4690-6-S3-P196  0.4
2009 Hirao LA, Wu L, Satishchandran A, Khan AS, Finnefrock A, Casimiro D, Shiver J, Betts MR, Sardesai NY, Weiner DB. OA05-02. Analysis of DNA compared to Ad5 vaccination, as single and mixed modalities, demonstrates robust induction of cellular immune responses in macaques Retrovirology. 6: O32. DOI: 10.1186/1742-4690-6-S3-O32  0.4
2009 Hirao LA, Wu L, Khan AS, Dai A, Karl J, Lank S, Wiseman R, O'Connor D, Watkins D, Miller N, Betts MR, Sardesai NY, Boyer JD, Weiner DB. P03-11. DNA vaccination with IL-12 lowers viral replication following SIVmac251 challenge Retrovirology. 6: P28.  0.4
2008 Person R, Bodles-Brakhop AM, Pope MA, Brown PA, Khan AS, Draghia-Akli R. Growth hormone-releasing hormone plasmid treatment by electroporation decreases offspring mortality over three pregnancies Molecular Therapy. 16: 1891-1897. PMID 18714311 DOI: 10.1038/mt.2008.178  0.4
2008 Lang KA, Yan J, Draghia-Akli R, Khan A, Weiner DB. Strong HCV NS3- and NS4A-specific cellular immune responses induced in mice and Rhesus macaques by a novel HCV genotype 1a/1b consensus DNA vaccine. Vaccine. 26: 6225-31. PMID 18692108 DOI: 10.1016/j.vaccine.2008.07.052  0.4
2008 Laddy DJ, Yan J, Kutzler M, Kobasa D, Kobinger GP, Khan AS, Greenhouse J, Sardesai NY, Draghia-Akli R, Weiner DB. Heterosubtypic protection against pathogenic human and avian influenza viruses via in vivo electroporation of synthetic consensus DNA antigens. Plos One. 3: e2517. PMID 18575608 DOI: 10.1371/journal.pone.0002517  0.4
2008 Muthumani K, Lankaraman KM, Laddy DJ, Sundaram SG, Chung CW, Sako E, Wu L, Khan A, Sardesai N, Kim JJ, Vijayachari P, Weiner DB. Immunogenicity of novel consensus-based DNA vaccines against Chikungunya virus. Vaccine. 26: 5128-34. PMID 18471943 DOI: 10.1016/j.vaccine.2008.03.060  0.4
2008 Rosati M, Valentin A, Jalah R, Patel V, von Gegerfelt A, Bergamaschi C, Alicea C, Weiss D, Treece J, Pal R, Markham PD, Marques ETA, August JT, Khan A, Draghia-Akli R, et al. Increased immune responses in rhesus macaques by DNA vaccination combined with electroporation Vaccine. 26: 5223-5229. PMID 18468743 DOI: 10.1016/j.vaccine.2008.03.090  0.4
2008 Yan J, Harris K, Khan AS, Draghia-Akli R, Sewell D, Weiner DB. Cellular immunity induced by a novel HPV18 DNA vaccine encoding an E6/E7 fusion consensus protein in mice and rhesus macaques. Vaccine. 26: 5210-5. PMID 18455277 DOI: 10.1016/j.vaccine.2008.03.069  0.4
2008 Draghia-Akli R, Khan AS, Brown PA, Pope MA, Wu L, Hirao L, Weiner DB. Parameters for DNA vaccination using adaptive constant-current electroporation in mouse and pig models. Vaccine. 26: 5230-7. PMID 18450333 DOI: 10.1016/j.vaccine.2008.03.071  0.4
2008 Hirao LA, Wu L, Khan AS, Hokey DA, Yan J, Dai A, Betts MR, Draghia-Akli R, Weiner DB. Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques. Vaccine. 26: 3112-20. PMID 18430495 DOI: 10.1016/j.vaccine.2008.02.036  0.4
2008 Draghia-Akli R, Khan AS. Muscle and fat mass modulation in different clinical models. Methods in Molecular Biology (Clifton, N.J.). 423: 449-60. PMID 18370221 DOI: 10.1007/978-1-59745-194-9_35  0.4
2008 Brown PA, Khan AS, Draghia-Akli R. Delivery of DNA into skeletal muscle in large animals. Methods in Molecular Biology (Clifton, N.J.). 423: 215-24. PMID 18370201 DOI: 10.1007/978-1-59745-194-9_15  0.4
2008 Hirao LA, Wu L, Khan AS, Satishchandran A, Draghia-Akli R, Weiner DB. Intradermal/subcutaneous immunization by electroporation improves plasmid vaccine delivery and potency in pigs and rhesus macaques. Vaccine. 26: 440-8. PMID 18082294 DOI: 10.1016/j.vaccine.2007.10.041  0.4
2008 Curcio C, Khan AS, Amici A, Spadaro M, Quaglino E, Cavallo F, Forni G, Draghia-Akli R. DNA immunization using constant-current electroporation affords long-term protection from autochthonous mammary carcinomas in cancer-prone transgenic mice. Cancer Gene Therapy. 15: 108-14. PMID 17992201 DOI: 10.1038/sj.cgt.7701106  0.4
2008 Storer WA, Thompson DL, Bondioli KR, Godke RA, Khan AS, Brown PA, Draghia-Akli R. Evaluation of Plasmid Delivery by Electroporation as a Means of Increasing Gonadotropin-Releasing Hormone Production in Stallions Journal of Equine Veterinary Science. 28: 149-155. DOI: 10.1016/j.jevs.2008.01.018  0.4
2007 Draghia-Akli R, Khan AS. In vivo electroporation of gene sequences for therapeutic and vaccination applications. Recent Patents On Dna & Gene Sequences. 1: 207-13. PMID 19075935  0.4
2006 Fiorotto ML, Lopez R, Oliver WT, Khan AS, Draghia-Akli R. Transplacental transfer of a growth hormone-releasing hormone peptide from mother to fetus in the rat. Dna and Cell Biology. 25: 429-37. PMID 16907640 DOI: 10.1089/dna.2006.25.429  0.4
2006 Prud'homme GJ, Glinka Y, Khan AS, Draghia-Akli R. Electroporation-enhanced nonviral gene transfer for the prevention or treatment of immunological, endocrine and neoplastic diseases. Current Gene Therapy. 6: 243-73. PMID 16611045 DOI: 10.2174/156652306776359504  0.4
2006 Draghia-Akli R, Pope MA, Brown PA, Khan AS. Plasmid-based expression technology using growth hormone releasing hormone: A novel method for physiologically stimulating long-term growth hormone secretion Combinatorial Chemistry and High Throughput Screening. 9: 181-185. PMID 16533151 DOI: 10.2174/138620706776055502  0.4
2006 Thacker EL, Holtkamp DJ, Khan AS, Brown PA, Draghia-Akli R. Plasmid-mediated growth hormone-releasing hormone efficacy in reducing disease associated with Mycoplasma hyopneumoniae and porcine reproductive and respiratory syndrome virus infection. Journal of Animal Science. 84: 733-42. PMID 16478966  0.4
2006 Hebel H, Attra H, Khan A, Draghia-Akli R. Successful parallel development and integration of a plasmid-based biologic, container/closure system and electrokinetic delivery device Vaccine. 24: 4607-4614. PMID 16150516 DOI: 10.1016/j.vaccine.2005.08.049  0.4
2005 Khan AS, Pope MA, Draghia-Akli R. Highly efficient constant-current electroporation increases in vivo plasmid expression Dna and Cell Biology. 24: 810-818. PMID 16332178 DOI: 10.1089/dna.2005.24.810  0.4
2005 Khan AS, Brown PA, Draghia-Akli R. Plasmid-based growth hormone-releasing hormone supplementation and its applications. Current Opinion in Molecular Therapeutics. 7: 306-16. PMID 16121696  0.4
2005 Khan AS, Smith LC, Anscombe IW, Cummings KK, Pope MA, Draghia-Akli R. Growth hormone releasing hormone plasmid supplementation, a potential treatment for cancer cachexia, does not increase tumor growth in nude mice Cancer Gene Therapy. 12: 54-60. PMID 15375378 DOI: 10.1038/sj.cgt.7700767  0.4
2003 Khan AS, Smith LC, Abruzzese RV, Cummings KK, Pope MA, Brown PA, Draghia-Akli R. Optimization of Electroporation Parameters for the Intramuscular Delivery of Plasmids in Pigs Dna and Cell Biology. 22: 807-814. PMID 14683591 DOI: 10.1089/104454903322625019  0.4
2003 Draghia-Akli R, Cummings KK, Khan AS, Brown PA, Carpenter RH. Effects of plasmid-mediated growth hormone releasing hormone supplementation in young, healthy Beagle dogs. Journal of Animal Science. 81: 2301-10. PMID 12968706  0.4
2003 Khan AS, Anscombe IW, Cummings KK, Pope MA, Smith LC, Draghia-Akli R. Effects of plasmid-mediated growth hormone-releasing hormone supplementation on LL-2 adenocarcinoma in mice Molecular Therapy. 8: 459-466. PMID 12946319 DOI: 10.1016/S1525-0016(03)00175-8  0.4
2003 Khan AS, Fiorotto ML, Cummings KK, Pope MA, Brown PA, Draghia-Akli R. Maternal GHRH plasmid administration changes pituitary cell lineage and improves progeny growth of pigs American Journal of Physiology - Endocrinology and Metabolism. 285: E224-E231. PMID 12670834  0.4
2002 Draghia-Akli R, Khan AS, Cummings KK, Parghi D, Carpenter RH, Brown PA. Electrical enhancement of formulated plasmid delivery in animals. Technology in Cancer Research & Treatment. 1: 365-72. PMID 12625762  0.4
2002 Khan AS, Fiorotto ML, Hill LA, Malone PB, Cummings KK, Parghi D, Schwartz RJ, Smith RG, Draghia-Akli R. Nonhereditary enhancement of progeny growth. Endocrinology. 143: 3561-7. PMID 12193571 DOI: 10.1210/en.2002-220282  0.4
2002 Khan AS, Sane DC, Wannenburg T, Sonntag WE. Growth hormone, insulin-like growth factor-1 and the aging cardiovascular system. Cardiovascular Research. 54: 25-35. PMID 12062358  0.4
2002 Khan AS, Sane DC, Wannenburg T, Sonntag WE. Repolarization abnormalities in heart failure Cardiovascular Research. 54: 11-12. PMID 12062355 DOI: 10.1016/S0008-6363(02)00249-3  0.4
2001 Saikh KU, Khan AS, Kissner T, Ulrich RG. IL-15-induced conversion of monocytes to mature dendritic cells Clinical and Experimental Immunology. 126: 447-455. PMID 11737061 DOI: 10.1046/j.1365-2249.2001.01672.x  0.4
2001 Khan AS, Lynch CD, Sane DC, Willingham MC, Sonntag WE. Growth hormone increases regional coronary blood flow and capillary density in aged rats. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 56: B364-71. PMID 11487595  0.4
2001 Wannenburg T, Khan AS, Sane DC, Willingham MC, Faucette T, Sonntag WE. Growth hormone reverses age-related cardiac myofilament dysfunction in rats. American Journal of Physiology. Heart and Circulatory Physiology. 281: H915-22. PMID 11454598  0.4
2001 Lynch CD, Lyons D, Khan A, Bennett SA, Sonntag WE. Insulin-like growth factor-1 selectively increases glucose utilization in brains of aged animals. Endocrinology. 142: 506-9. PMID 11145617 DOI: 10.1210/endo.142.1.8053  0.4
2000 Sonntag WE, Lynch C, Thornton P, Khan A, Bennett S, Ingram R. The effects of growth hormone and IGF-1 deficiency on cerebrovascular and brain ageing. Journal of Anatomy. 197: 575-85. PMID 11197531 DOI: 10.1017/S002187829900713X  0.4
2000 Sonntag WE, Bennett SA, Khan AS, Thornton PL, Xu X, Ingram RL, Brunso-Bechtold JK. Age and insulin-like growth factor-1 modulate N-methyl-D-aspartate receptor subtype expression in rats. Brain Research Bulletin. 51: 331-8. PMID 10704784 DOI: 10.1016/S0361-9230(99)00259-2  0.4
1999 Sonntag WE, Lynch CD, Cefalu WT, Ingram RL, Bennett SA, Thornton PL, Khan AS. Pleiotropic effects of growth hormone and insulin-like growth factor (IGF)-1 on biological aging: inferences from moderate caloric-restricted animals. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 54: B521-38. PMID 10647962  0.4
1999 Lynch CD, Cooney PT, Bennett SA, Thornton PL, Khan AS, Ingram RL, Sonntag WE. Effects of moderate caloric restriction on cortical microvascular density and local cerebral blood flow in aged rats. Neurobiology of Aging. 20: 191-200. PMID 10537028 DOI: 10.1016/S0197-4580(99)00032-9  0.4
1999 Sonntag WE, Lynch CD, Bennett SA, Khan AS, Thornton PL, Cooney PT, Ingram RL, McShane T, Brunso-Bechtold JK. Alterations in insulin-like growth factor-1 gene and protein expression and type 1 insulin-like growth factor receptors in the brains of ageing rats. Neuroscience. 88: 269-79. PMID 10051206 DOI: 10.1016/S0306-4522(98)00192-4  0.4
1998 Nuckolls FJ, Khan AS, Butler R, Katula KS. Differential response of the human cyclin B1 promoter to inhibitors of the cell cycle in NIH3T3 cells Biochemical and Biophysical Research Communications. 244: 280-284. PMID 9514874 DOI: 10.1006/bbrc.1998.8205  0.4
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