| Year |
Citation |
Score |
| 2020 |
Chen PB, Black AS, Sobel AL, Zhao Y, Mukherjee P, Molparia B, Moore NE, Aleman Muench GR, Wu J, Chen W, Pinto AFM, Maryanoff BE, Saghatelian A, Soroosh P, Torkamani A, ... Leman LJ, et al. Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis. Nature Biotechnology. PMID 32541956 DOI: 10.1038/S41587-020-0549-5 |
0.706 |
|
| 2020 |
Frenkel-Pinter M, Samanta M, Ashkenasy G, Leman LJ. Prebiotic Peptides: Molecular Hubs in the Origin of Life. Chemical Reviews. PMID 32101414 DOI: 10.1021/acs.chemrev.9b00664 |
0.348 |
|
| 2018 |
Mukherjee P, Leman LJ, Griffin JH, Ghadiri MR. Design of a DNA-programmed plasminogen activator. Journal of the American Chemical Society. PMID 30347143 DOI: 10.1021/Jacs.8B10166 |
0.598 |
|
| 2017 |
Beierle JM, Ura Y, Ghadiri MR, Leman LJ. Templated Self-Assembly of Dynamic Peptide Nucleic Acids. Biochemistry. PMID 28832127 DOI: 10.1021/acs.biochem.7b00656 |
0.647 |
|
| 2017 |
Zhao Y, Leman LJ, Search DJ, Garcia RA, Gordon DA, Maryanoff BE, Ghadiri MR. Self-Assembling Cyclic d,l-α-Peptides as Modulators of Plasma HDL Function. A Supramolecular Approach toward Antiatherosclerotic Agents. Acs Central Science. 3: 639-646. PMID 28691076 DOI: 10.1021/Acscentsci.7B00154 |
0.673 |
|
| 2017 |
Lai JI, Leman LJ, Ku S, Vickers CJ, Olsen CA, Montero A, Ghadiri MR, Gottesfeld JM. Cyclic tetrapeptide HDAC inhibitors as potential therapeutics for spinal muscular atrophy: Screening with iPSC-derived neuronal cells. Bioorganic & Medicinal Chemistry Letters. PMID 28648462 DOI: 10.1016/J.Bmcl.2017.06.027 |
0.666 |
|
| 2016 |
Maolanon AR, Kristensen HM, Leman LJ, Ghadiri MR, Olsen CA. Natural and Synthetic Macrocyclic Inhibitors of the Histone Deacetylase Enzymes. Chembiochem : a European Journal of Chemical Biology. PMID 27748555 DOI: 10.1002/Cbic.201600519 |
0.695 |
|
| 2016 |
Leman L, Ghadiri M. Potentially Prebiotic Synthesis of α-Amino Thioacids in Water Synlett. 28: 68-72. DOI: 10.1055/s-0036-1589410 |
0.59 |
|
| 2015 |
Leman LJ, Huang ZZ, Ghadiri MR. Peptide Bond Formation in Water Mediated by Carbon Disulfide. Astrobiology. 15: 709-16. PMID 26308392 DOI: 10.1089/ast.2015.1314 |
0.68 |
|
| 2014 |
Zhao Y, Black AS, Bonnet DJ, Maryanoff BE, Curtiss LK, Leman LJ, Ghadiri MR. In vivo efficacy of HDL-like nanolipid particles containing multivalent peptide mimetics of apolipoprotein A-I. Journal of Lipid Research. 55: 2053-63. PMID 24975585 DOI: 10.1194/jlr.M049262 |
0.635 |
|
| 2014 |
Leman LJ, Maryanoff BE, Ghadiri MR. Molecules that mimic apolipoprotein A-I: potential agents for treating atherosclerosis. Journal of Medicinal Chemistry. 57: 2169-96. PMID 24168751 DOI: 10.1021/jm4005847 |
0.638 |
|
| 2013 |
Zhao Y, Imura T, Leman LJ, Curtiss LK, Maryanoff BE, Ghadiri MR. Mimicry of high-density lipoprotein: functional peptide-lipid nanoparticles based on multivalent peptide constructs. Journal of the American Chemical Society. 135: 13414-24. PMID 23978057 DOI: 10.1021/Ja404714A |
0.652 |
|
| 2012 |
Olsen CA, Montero A, Leman LJ, Ghadiri MR. Macrocyclic peptoid-Peptide hybrids as inhibitors of class I histone deacetylases. Acs Medicinal Chemistry Letters. 3: 749-53. PMID 24900543 DOI: 10.1021/Ml300162R |
0.706 |
|
| 2012 |
Vickers CJ, Olsen CA, Leman LJ, Ghadiri MR. Discovery of HDAC Inhibitors That Lack an Active Site Zn(2+)-Binding Functional Group. Acs Medicinal Chemistry Letters. 3: 505-8. PMID 24900500 DOI: 10.1021/Ml300081U |
0.7 |
|
| 2011 |
Hutt DM, Olsen CA, Vickers CJ, Herman D, Chalfant M, Montero A, Leman LJ, Burkle R, Maryanoff BE, Balch WE, Ghadiri MR. Potential Agents for Treating Cystic Fibrosis: Cyclic Tetrapeptides that Restore Trafficking and Activity of ΔF508-CFTR. Acs Medicinal Chemistry Letters. 2: 703-707. PMID 21984958 DOI: 10.1021/Ml200136E |
0.682 |
|
| 2009 |
Ura Y, Al-Sayah M, Montenegro J, Beierle JM, Leman LJ, Ghadiri MR. Dynamic polythioesters via ring-opening polymerization of 1,4-thiazine-2,5-diones. Organic & Biomolecular Chemistry. 7: 2878-84. PMID 19582297 DOI: 10.1039/B903612A |
0.719 |
|
| 2009 |
Ura Y, Beierle JM, Leman LJ, Orgel LE, Ghadiri MR. Self-assembling sequence-adaptive peptide nucleic acids. Science (New York, N.Y.). 325: 73-7. PMID 19520909 DOI: 10.1126/Science.1174577 |
0.666 |
|
| 2008 |
Huang ZZ, Leman LJ, Ghadiri MR. Biomimetic catalysis of diketopiperazine and dipeptide syntheses. Angewandte Chemie (International Ed. in English). 47: 1758-61. PMID 18213666 DOI: 10.1002/anie.200704266 |
0.602 |
|
| 2007 |
Leman LJ, Weinberger DA, Huang ZZ, Wilcoxen KM, Ghadiri MR. Functional and mechanistic analyses of biomimetic aminoacyl transfer reactions in de novo designed coiled coil peptides via rational active site engineering. Journal of the American Chemical Society. 129: 2959-66. PMID 17302417 DOI: 10.1021/Ja068052X |
0.757 |
|
| 2007 |
Wilcoxen KM, Leman LJ, Weinberger DA, Huang ZZ, Ghadiri MR. Biomimetic catalysis of intermodular aminoacyl transfer. Journal of the American Chemical Society. 129: 748-9. PMID 17243796 DOI: 10.1021/Ja067124H |
0.753 |
|
| 2006 |
Yadav MK, Leman LJ, Price DJ, Brooks CL, Stout CD, Ghadiri MR. Coiled coils at the edge of configurational heterogeneity. Structural analyses of parallel and antiparallel homotetrameric coiled coils reveal configurational sensitivity to a single solvent-exposed amino acid substitution. Biochemistry. 45: 4463-73. PMID 16584182 DOI: 10.1021/Bi060092Q |
0.645 |
|
| 2006 |
Leman LJ, Orgel LE, Ghadiri MR. Amino acid dependent formation of phosphate anhydrides in water mediated by carbonyl sulfide. Journal of the American Chemical Society. 128: 20-1. PMID 16390101 DOI: 10.1021/Ja056036E |
0.635 |
|
| 2005 |
Yadav MK, Redman JE, Leman LJ, Alvarez-Gutiérrez JM, Zhang Y, Stout CD, Ghadiri MR. Structure-based engineering of internal cavities in coiled-coil peptides. Biochemistry. 44: 9723-32. PMID 16008357 DOI: 10.1021/bi050742a |
0.679 |
|
| 2004 |
Leman L, Orgel L, Ghadiri MR. Carbonyl sulfide-mediated prebiotic formation of peptides. Science (New York, N.Y.). 306: 283-6. PMID 15472077 DOI: 10.1126/Science.1102722 |
0.665 |
|
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