Denise M. Kenski, Ph.D. - Publications

Affiliations: 
2005 University of California, San Francisco, San Francisco, CA 
Area:
signal transduction pathways in cells and whole organisms

13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Kenski DM, Willingham AT, Haringsma HJ, Li JJ, Flanagan WM. In vivo activity and duration of short interfering RNAs containing a synthetic 5'-phosphate. Nucleic Acid Therapeutics. 22: 90-5. PMID 22400991 DOI: 10.1089/Nat.2011.0333  0.364
2012 Haringsma HJ, Li JJ, Soriano F, Kenski DM, Flanagan WM, Willingham AT. mRNA knockdown by single strand RNA is improved by chemical modifications. Nucleic Acids Research. 40: 4125-36. PMID 22253019 DOI: 10.1093/Nar/Gkr1301  0.311
2011 Butora G, Kenski DM, Cooper AJ, Fu W, Qi N, Li JJ, Flanagan WM, Davies IW. Nucleoside optimization for RNAi: a high-throughput platform. Journal of the American Chemical Society. 133: 16766-9. PMID 21942264 DOI: 10.1021/Ja2068774  0.316
2010 Kenski DM, Cooper AJ, Li JJ, Willingham AT, Haringsma HJ, Young TA, Kuklin NA, Jones JJ, Cancilla MT, McMasters DR, Mathur M, Sachs AB, Flanagan WM. Analysis of acyclic nucleoside modifications in siRNAs finds sensitivity at position 1 that is restored by 5'-terminal phosphorylation both in vitro and in vivo. Nucleic Acids Research. 38: 660-71. PMID 19917641 DOI: 10.1093/Nar/Gkp913  0.426
2009 Jaiswal BS, Janakiraman V, Kljavin NM, Chaudhuri S, Stern HM, Wang W, Kan Z, Dbouk HA, Peters BA, Waring P, Dela Vega T, Kenski DM, Bowman KK, Lorenzo M, Li H, et al. Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation. Cancer Cell. 16: 463-74. PMID 19962665 DOI: 10.1016/J.Ccr.2009.10.016  0.389
2009 Murriel CL, Chen H, Kenski D, Bou-Reslan H, Yuan W, Liang Y, Carano R, Couto S, Seshagiri S, Davis DP, Johson L. Abstract LB-189: BRAFdeletion and pharmacological inhibition enhance K-ras driven tumorigenesis Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-189  0.326
2006 Kung C, Kenski DM, Krukenberg K, Madhani HD, Shokat KM. Selective kinase inhibition by exploiting differential pathway sensitivity. Chemistry & Biology. 13: 399-407. PMID 16632252 DOI: 10.1016/J.Chembiol.2006.02.004  0.671
2005 Kenski DM, Zhang C, von Zastrow M, Shokat KM. Chemical genetic engineering of G protein-coupled receptor kinase 2. The Journal of Biological Chemistry. 280: 35051-61. PMID 16081410 DOI: 10.1074/Jbc.M507594200  0.632
2005 Zhang C, Kenski DM, Paulson JL, Bonshtien A, Sessa G, Cross JV, Templeton DJ, Shokat KM. A second-site suppressor strategy for chemical genetic analysis of diverse protein kinases. Nature Methods. 2: 435-41. PMID 15908922 DOI: 10.1038/Nmeth764  0.709
2005 Kung C, Kenski DM, Dickerson SH, Howson RW, Kuyper LF, Madhani HD, Shokat KM. Chemical genomic profiling to identify intracellular targets of a multiplex kinase inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 102: 3587-92. PMID 15738404 DOI: 10.1073/Pnas.0407170102  0.685
2004 Knight ZA, Chiang GG, Alaimo PJ, Kenski DM, Ho CB, Coan K, Abraham RT, Shokat KM. Isoform-specific phosphoinositide 3-kinase inhibitors from an arylmorpholine scaffold. Bioorganic & Medicinal Chemistry. 12: 4749-59. PMID 15358300 DOI: 10.1016/J.Bmc.2004.06.022  0.593
2003 Knight ZA, Schilling B, Row RH, Kenski DM, Gibson BW, Shokat KM. Phosphospecific proteolysis for mapping sites of protein phosphorylation. Nature Biotechnology. 21: 1047-54. PMID 12923550 DOI: 10.1038/Nbt863  0.66
2003 Ulrich SM, Kenski DM, Shokat KM. Engineering a "methionine clamp" into Src family kinases enhances specificity toward unnatural ATP analogues. Biochemistry. 42: 7915-21. PMID 12834343 DOI: 10.1021/Bi030042A  0.712
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