Year |
Citation |
Score |
2024 |
Akther T, McFadden WM, Zhang H, Kirby KA, Sarafianos SG, Wang Z. Design and Synthesis of New GS-6207 Subtypes for Targeting HIV-1 Capsid Protein. International Journal of Molecular Sciences. 25. PMID 38612545 DOI: 10.3390/ijms25073734 |
0.335 |
|
2023 |
Jagtap AD, Geraghty RJ, Wang Z. Inhibiting HCMV pUL89-C Endonuclease with Metal-Binding Compounds. Journal of Medicinal Chemistry. 66: 13874-13887. PMID 37827528 DOI: 10.1021/acs.jmedchem.3c01280 |
0.313 |
|
2023 |
Dsouza L, Pant A, Offei S, Priyamvada L, Pope B, Satheshkumar PS, Wang Z, Yang Z. Antiviral activities of two nucleos(t)ide analogs against vaccinia, mpox, and cowpox viruses in primary human fibroblasts. Antiviral Research. 216: 105651. PMID 37270160 DOI: 10.1016/j.antiviral.2023.105651 |
0.333 |
|
2023 |
Dsouza L, Pant A, Offei S, Priyamvada L, Pope B, Satheshkumar PS, Wang Z, Yang Z. Antiviral activities of two nucleos(t)ide analogs against vaccinia and mpox viruses in primary human fibroblasts. Biorxiv : the Preprint Server For Biology. PMID 36993701 DOI: 10.1101/2023.03.23.533943 |
0.337 |
|
2022 |
He T, Edwards TC, Majima R, Jung E, Kankanala J, Xie J, Geraghty RJ, Wang Z. Repurposing N-hydroxy thienopyrimidine-2,4-diones (HtPD) as inhibitors of human cytomegalovirus pUL89 endonuclease: Synthesis and biological characterization. Bioorganic Chemistry. 129: 106198. PMID 36265353 DOI: 10.1016/j.bioorg.2022.106198 |
0.415 |
|
2022 |
Jung E, Majima R, Edwards TC, Soto-Acosta R, Geraghty RJ, Wang Z. 8-Hydroxy-1,6-naphthyridine-7-carboxamides as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease. Chemmedchem. PMID 35879245 DOI: 10.1002/cmdc.202200334 |
0.343 |
|
2021 |
Senaweera S, Edwards TC, Kankanala J, Wang Y, Sahani RL, Xie J, Geraghty RJ, Wang Z. Discovery of -benzyl hydroxypyridone carboxamides as a novel and potent antiviral chemotype against human cytomegalovirus (HCMV). Acta Pharmaceutica Sinica. B. 12: 1671-1684. PMID 35847513 DOI: 10.1016/j.apsb.2021.08.019 |
0.317 |
|
2021 |
Sahani RL, Akther T, Cilento ME, Castaner AE, Zhang H, Kirby KA, Xie J, Sarafianos SG, Wang Z. Potency and metabolic stability: a molecular hybrid case in the design of novel PF74-like small molecules targeting HIV-1 capsid protein. Rsc Medicinal Chemistry. 12: 2031-2044. PMID 35028563 DOI: 10.1039/d1md00292a |
0.355 |
|
2021 |
McFadden WM, Snyder AA, Kirby KA, Tedbury PR, Raj M, Wang Z, Sarafianos SG. Rotten to the core: antivirals targeting the HIV-1 capsid core. Retrovirology. 18: 41. PMID 34937567 DOI: 10.1186/s12977-021-00583-z |
0.395 |
|
2021 |
Wang L, Edwards TC, Sahani RL, Xie J, Aihara H, Geraghty RJ, Wang Z. Metal binding 6-arylthio-3-hydroxypyrimidine-2,4-diones inhibited human cytomegalovirus by targeting the pUL89 endonuclease of the terminase complex. European Journal of Medicinal Chemistry. 222: 113640. PMID 34147908 DOI: 10.1016/j.ejmech.2021.113640 |
0.343 |
|
2021 |
Sahani RL, Diana-Rivero R, Vernekar SKV, Wang L, Du H, Zhang H, Castaner AE, Casey MC, Kirby KA, Tedbury PR, Xie J, Sarafianos SG, Wang Z. Design, Synthesis and Characterization of HIV-1 CA-Targeting Small Molecules: Conformational Restriction of PF74. Viruses. 13. PMID 33804121 DOI: 10.3390/v13030479 |
0.676 |
|
2021 |
Wang L, Casey MC, Vernekar SKV, Sahani RL, Kirby KA, Du H, Zhang H, Tedbury PR, Xie J, Sarafianos SG, Wang Z. Novel PF74-like small molecules targeting the HIV-1 capsid protein: Balance of potency and metabolic stability. Acta Pharmaceutica Sinica. B. 11: 810-822. PMID 33777683 DOI: 10.1016/J.Apsb.2020.07.016 |
0.692 |
|
2021 |
Senaweera S, He T, Cui H, Aihara H, Wang Z. 4-Benzylideneisoquinoline-1,3(,)-diones as tyrosyl DNA phosphodiesterase 2 (TDP2) inhibitors. Medicinal Chemistry Research : An International Journal For Rapid Communications On Design and Mechanisms of Action of Biologically Active Agents. 30: 371-386. PMID 33776385 DOI: 10.1007/s00044-020-02662-w |
0.339 |
|
2020 |
Wang L, Casey MC, Vernekar SKV, Sahani RL, Kankanala J, Kirby KA, Du H, Hachiya A, Zhang H, Tedbury PR, Xie J, Sarafianos SG, Wang Z. Novel HIV-1 capsid-targeting small molecules of the PF74 binding site. European Journal of Medicinal Chemistry. 204: 112626. PMID 32814250 DOI: 10.1016/J.Ejmech.2020.112626 |
0.688 |
|
2020 |
Wang L, Casey MC, Vernekar SKV, Do HT, Sahani RL, Kirby KA, Du H, Hachiya A, Zhang H, Tedbury PR, Xie J, Sarafianos SG, Wang Z. Chemical profiling of HIV-1 capsid-targeting antiviral PF74. European Journal of Medicinal Chemistry. 200: 112427. PMID 32438252 DOI: 10.1016/J.Ejmech.2020.112427 |
0.676 |
|
2020 |
Vernekar SKV, Sahani RL, Casey MC, Kankanala J, Wang L, Kirby KA, Du H, Zhang H, Tedbury PR, Xie J, Sarafianos SG, Wang Z. Toward Structurally Novel and Metabolically Stable HIV-1 Capsid-Targeting Small Molecules. Viruses. 12. PMID 32316297 DOI: 10.3390/V12040452 |
0.715 |
|
2020 |
Dang X, Ogbu SC, Zhao J, Nguyen LNT, Cao D, Nguyen LN, Khanal S, Schank M, Thakuri BKC, Wu XY, Morrison ZD, Zhang J, Li Z, El Gazzar M, Ning S, ... ... Wang Z, et al. Inhibition of topoisomerase IIA (Top2α) induces telomeric DNA damage and T cell dysfunction during chronic viral infection. Cell Death & Disease. 11: 196. PMID 32193368 DOI: 10.1038/S41419-020-2395-2 |
0.327 |
|
2019 |
Wang L, Sarafianos SG, Wang Z. Cutting into the Substrate Dominance: Pharmacophore and Structure-Based Approaches toward Inhibiting Human Immunodeficiency Virus Reverse Transcriptase-Associated Ribonuclease H. Accounts of Chemical Research. PMID 31880912 DOI: 10.1021/Acs.Accounts.9B00450 |
0.55 |
|
2019 |
Kiselev E, Ravji A, Kankanala J, Xie J, Wang Z, Pommier Y. Novel deazaflavin tyrosyl-DNA phosphodiesterase 2 (TDP2) inhibitors. Dna Repair. 85: 102747. PMID 31775111 DOI: 10.1016/J.Dnarep.2019.102747 |
0.446 |
|
2019 |
Xi Z, Wang Z, Sarafianos SG, Myshakina NS, Ishima R. Determinants of Active-Site Inhibitor Interaction with HIV-1 RNase H. Acs Infectious Diseases. PMID 31577424 DOI: 10.1021/Acsinfecdis.9B00300 |
0.45 |
|
2019 |
Kankanala J, Ribeiro CJA, Kiselev E, Ravji A, Williams J, Xie J, Aihara H, Pommier Y, Wang Z. Novel deazaflavin analogues potently inhibited tyrosyl DNA phosphodiesterase 2 (TDP2) and strongly sensitized cancer cells toward treatment with topoisomerase II (TOP2) poison etoposide. Journal of Medicinal Chemistry. PMID 30998359 DOI: 10.1021/Acs.Jmedchem.9B00274 |
0.376 |
|
2019 |
Tang J, Do HT, Huber AD, Casey MC, Kirby KA, Wilson DJ, Kankanala J, Parniak MA, Sarafianos SG, Wang Z. Pharmacophore-based design of novel 3-hydroxypyrimidine-2,4-dione subtypes as inhibitors of HIV reverse transcriptase-associated RNase H: Tolerance of a nonflexible linker. European Journal of Medicinal Chemistry. 166: 390-399. PMID 30739822 DOI: 10.1016/J.Ejmech.2019.01.081 |
0.578 |
|
2018 |
Tang J, Huber AD, Pineda DL, Boschert KN, Wolf JJ, Kankanala J, Xie J, Sarafianos SG, Wang Z. 5-Aminothiophene-2,4-dicarboxamide analogues as hepatitis B virus capsid assembly effectors. European Journal of Medicinal Chemistry. 164: 179-192. PMID 30594676 DOI: 10.1016/J.Ejmech.2018.12.047 |
0.371 |
|
2018 |
Huber AD, Pineda DL, Liu D, Boschert KN, Gres AT, Wolf JJ, Coonrod EM, Tang J, Laughlin TG, Yang Q, Puray-Chavez M, Ji J, Singh K, Kirby KA, Wang Z, et al. Novel Hepatitis B Virus Capsid-Targeting Antiviral that Aggregates Core Particles and Inhibits Nuclear Entry of Viral Cores. Acs Infectious Diseases. PMID 30582687 DOI: 10.1021/Acsinfecdis.8B00235 |
0.377 |
|
2018 |
Ribeiro CJA, Kankanala J, Xie J, Williams J, Aihara H, Wang Z. Triazolopyrimidine and triazolopyridine scaffolds as TDP2 inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 30522956 DOI: 10.1016/J.Bmcl.2018.11.044 |
0.372 |
|
2018 |
Wang L, Tang J, Huber AD, Casey MC, Kirby KA, Wilson DJ, Kankanala J, Parniak MA, Sarafianos SG, Wang Z. 6-Biphenylmethyl-3-hydroxypyrimidine-2,4-diones potently and selectively inhibited HIV reverse transcriptase-associated RNase H. European Journal of Medicinal Chemistry. 156: 680-691. PMID 30031978 DOI: 10.1016/J.Ejmech.2018.07.035 |
0.542 |
|
2018 |
Wang L, Tang J, Huber AD, Casey MC, Kirby KA, Wilson DJ, Kankanala J, Xie J, Parniak MA, Sarafianos SG, Wang Z. 6-Arylthio-3-hydroxypyrimidine-2,4-diones potently inhibited HIV reverse transcriptase-associated RNase H with antiviral activity. European Journal of Medicinal Chemistry. 156: 652-665. PMID 30031976 DOI: 10.1016/J.Ejmech.2018.07.039 |
0.549 |
|
2018 |
Kankanala J, Wang Y, Geraghty RJ, Wang Z. Hydroxypyridonecarboxylic acids as inhibitors of human cytomegalovirus pUL89 endonuclease. Chemmedchem. PMID 29968426 DOI: 10.1002/Cmdc.201800283 |
0.441 |
|
2018 |
Bohl TE, Ieong P, Lee JK, Lee T, Kankanala J, Shi K, Demir Ö, Kurahashi K, Amaro RE, Wang Z, Aihara H. The substrate-binding cap of the UDP-diacylglucosamine pyrophosphatase LpxH is highly flexible, enabling facile substrate binding and product release. The Journal of Biological Chemistry. PMID 29626094 DOI: 10.1074/Jbc.Ra118.002503 |
0.339 |
|
2018 |
Ribeiro CJA, Kankanala J, Shi K, Kurahashi K, Kiselev E, Ravji A, Pommier Y, Aihara H, Wang Z. New fluorescence-based high-throughput screening assay for small molecule inhibitors of tyrosyl-DNA phosphodiesterase 2 (TDP2). European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 29574079 DOI: 10.1016/J.Ejps.2018.03.021 |
0.396 |
|
2018 |
Wang Y, Tang J, Wang Z, Geraghty RJ. Metal-chelating 3-hydroxypyrimidine-2,4-diones inhibit human cytomegalovirus pUL89 endonuclease activity and virus replication. Antiviral Research. PMID 29425830 DOI: 10.1016/J.Antiviral.2018.01.015 |
0.472 |
|
2017 |
Kankanala J, Kirby KA, Huber AD, Casey MC, Wilson DJ, Sarafianos SG, Wang Z. Design, synthesis and biological evaluations of N-Hydroxy thienopyrimidine-2,4-diones as inhibitors of HIV reverse transcriptase-associated RNase H. European Journal of Medicinal Chemistry. 141: 149-161. PMID 29031062 DOI: 10.1016/J.Ejmech.2017.09.054 |
0.549 |
|
2017 |
Kirby KA, Myshakina NA, Christen MT, Chen YL, Schmidt HA, Huber AD, Xi Z, Kim S, Rao RK, Kramer ST, Yang Q, Singh K, Parniak MA, Wang Z, Ishima R, et al. A 2-hydroxyisoquinoline-1,3-dione active site RNase H inhibitor binds in multiple modes to HIV-1 reverse transcriptase. Antimicrobial Agents and Chemotherapy. PMID 28760905 DOI: 10.1128/Aac.01351-17 |
0.66 |
|
2017 |
Vernekar SKV, Tang J, Wu B, Huber AD, Casey MC, Myshakina NS, Wilson DJ, Kankanala J, Kirby KA, Parniak MA, Sarafianos SG, Wang Z. Double-winged 3-Hydroxypyrimidine-2,4-diones: Potent and Selective Inhibition against HIV-1 RNase H with Significant Antiviral Activity. Journal of Medicinal Chemistry. PMID 28525279 DOI: 10.1021/Acs.Jmedchem.7B00440 |
0.725 |
|
2017 |
Tang J, Vernekar SK, Chen YL, Miller L, Huber AD, Myshakina N, Sarafianos SG, Parniak MA, Wang Z. Synthesis, biological evaluation and molecular modeling of 2-Hydroxyisoquinoline-1,3-dione analogues as inhibitors of HIV reverse transcriptase associated ribonuclease H and polymerase. European Journal of Medicinal Chemistry. 133: 85-96. PMID 28384548 DOI: 10.1016/J.Ejmech.2017.03.059 |
0.775 |
|
2017 |
Huber AD, Michailidis E, Tang J, Puray-Chavez MN, Boftsi M, Wolf JJ, Boschert KN, Sheridan MA, Leslie MD, Kirby KA, Singh K, Mitsuya H, Parniak MA, Wang Z, Sarafianos SG. 3-hydroxypyrimidine-2,4-diones as novel hepatitis B virus antivirals targeting the viral ribonuclease H. Antimicrobial Agents and Chemotherapy. PMID 28320718 DOI: 10.1128/Aac.00245-17 |
0.379 |
|
2017 |
Tang J, Kirby KA, Huber AD, Casey MC, Ji J, Wilson DJ, Sarafianos SG, Wang Z. 6-Cyclohexylmethyl-3-hydroxypyrimidine-2,4-dione as an inhibitor scaffold of HIV reverase transcriptase: Impacts of the 3-OH on inhibiting RNase H and polymerase. European Journal of Medicinal Chemistry. 128: 168-179. PMID 28182989 DOI: 10.1016/J.Ejmech.2017.01.041 |
0.549 |
|
2016 |
Wang Y, Mao L, Kankanala J, Wang Z, Geraghty RJ. Inhibition of Human Cytomegalovirus pUL89 Terminase Subunit Blocks Virus Replication and Genome Cleavage. Journal of Virology. PMID 27881652 DOI: 10.1128/Jvi.02152-16 |
0.429 |
|
2016 |
Wu B, Tang J, Wilson DJ, Huber AD, Casey MC, Ji J, Kankanala J, Xie J, Sarafianos SG, Wang Z. 3-Hydroxypyrimidine-2,4-dione-5-N-benzylcarboxamides potently inhibit HIV-1 integrase and RNase H. Journal of Medicinal Chemistry. PMID 27283261 DOI: 10.1021/Acs.Jmedchem.6B00040 |
0.558 |
|
2016 |
Marchand C, Abdelmalak M, Kankanala J, Huang SY, Kiselev E, Fesen K, Kurahashi K, Sasanuma H, Takeda S, Aihara H, Wang Z, Pommier Y. Deazaflavin inhibitors of tyrosyl-DNA phosphodiesterase 2 (TDP2) specific for the human enzyme and active against cellular TDP2. Acs Chemical Biology. PMID 27128689 DOI: 10.1021/Acschembio.5B01047 |
0.403 |
|
2016 |
Kankanala J, Kirby KA, Liu F, Miller LG, Nagy E, Wilson DJ, Parniak MA, Sarafianos SG, Wang Z. Design, Synthesis and Biological Evaluations of Hydroxypyridone Carboxylic Acids as Inhibitors of HIV Reverse Transcriptase-Associated RNase H. Journal of Medicinal Chemistry. PMID 27094954 DOI: 10.1021/Acs.Jmedchem.6B00465 |
0.54 |
|
2016 |
Tang J, Liu F, Nagy E, Miller LG, Kirby KA, Wilson DJ, Wu B, Sarafianos SG, Parniak MA, Wang Z. 2-Hydroxypyrimidine-2,4-diones as Selective Active Site Inhibitors of HIV Reverse Transcriptase-Associated RNase H: Design, Synthesis, and Biochemical Evaluations. Journal of Medicinal Chemistry. PMID 26927866 DOI: 10.1021/Acs.Jmedchem.5B01879 |
0.538 |
|
2016 |
Kankanala J, Marchand C, Abdelmalak M, Aihara H, Pommier Y, Wang Z. Isoquinoline-1,3-diones as Selective Inhibitors of Tyrosyl DNA Phosphodiesterase II (TDP2). Journal of Medicinal Chemistry. PMID 26910725 DOI: 10.1021/Acs.Jmedchem.5B01973 |
0.403 |
|
2016 |
Chen Y, Chen L, Ou Y, Wang Z, Fu F, Guo L. DNAzyme-based biosensor for Cu2+ ion by combining hybridization chain reaction with fluorescence resonance energy transfer technique Talanta. 155: 245-249. DOI: 10.1016/j.talanta.2016.04.057 |
0.431 |
|
2016 |
He B, Wang ZJ, Chen YN, Zhang ZD. Enhanced magnetic and ferroelectric properties in Pb(Zr0.52Ti0.48)O3/La0.7Ca0.3MnO3 bilayers grown on Nb-doped (110) SrTiO3 substrate Journal of Alloys and Compounds. 680: 565-570. DOI: 10.1016/j.jallcom.2016.04.177 |
0.414 |
|
2016 |
Gang C, Wang Z, Chen Y, Yang Y, Li J, Cheng J, Qi J, Odeh I. Drought-induced dynamics of carbon and water use efficiency of global grasslands from 2000 to 2011 Ecological Indicators. 67: 788-797. DOI: 10.1016/J.Ecolind.2016.03.049 |
0.433 |
|
2016 |
Wang Z, Chen Y, Xie P, Shang R, Ma J. Removal of Microcystis aeruginosa by UV-activated persulfate: Performance and characteristics Chemical Engineering Journal. 300: 245-253. DOI: 10.1016/j.cej.2016.04.125 |
0.451 |
|
2015 |
Vernekar SK, Qiu L, Zhang J, Kankanala J, Li H, Geraghty RJ, Wang Z. 5'-Silylated 3'-1,2,3-triazolyl Thymidine Analogues as Inhibitors of West Nile Virus and Dengue Virus. Journal of Medicinal Chemistry. 58: 4016-28. PMID 25909386 DOI: 10.1021/Acs.Jmedchem.5B00327 |
0.708 |
|
2015 |
Vernekar SK, Liu Z, Nagy E, Miller L, Kirby KA, Wilson DJ, Kankanala J, Sarafianos SG, Parniak MA, Wang Z. Design, synthesis, biochemical, and antiviral evaluations of C6 benzyl and C6 biarylmethyl substituted 2-hydroxylisoquinoline-1,3-diones: dual inhibition against HIV reverse transcriptase-associated RNase H and polymerase with antiviral activities. Journal of Medicinal Chemistry. 58: 651-64. PMID 25522204 DOI: 10.1021/Jm501132S |
0.723 |
|
2014 |
Vernekar SKV, Qiu L, Zacharias J, Geraghty RJ, Wang Z. Synthesis and antiviral evaluation of 4′-(1,2,3-triazol-1-yl) thymidines Medchemcomm. 5: 603-608. DOI: 10.1039/C4Md00039K |
0.732 |
|
2013 |
Sirivolu VR, Vernekar SK, Ilina T, Myshakina NS, Parniak MA, Wang Z. Clicking 3'-azidothymidine into novel potent inhibitors of human immunodeficiency virus. Journal of Medicinal Chemistry. 56: 8765-80. PMID 24102161 DOI: 10.1021/Jm401232V |
0.795 |
|
2012 |
Sirivolu VR, Vernekar SK, Marchand C, Naumova A, Chergui A, Renaud A, Stephen AG, Chen F, Sham YY, Pommier Y, Wang Z. 5-Arylidenethioxothiazolidinones as inhibitors of tyrosyl-DNA phosphodiesterase I. Journal of Medicinal Chemistry. 55: 8671-84. PMID 23006064 DOI: 10.1021/Jm3008773 |
0.769 |
|
2012 |
Chen YL, Zacharias J, Vince R, Geraghty RJ, Wang Z. C-6 aryl substituted 4-quinolone-3-carboxylic acids as inhibitors of hepatitis C virus. Bioorganic & Medicinal Chemistry. 20: 4790-800. PMID 22748708 DOI: 10.1016/J.Bmc.2012.05.066 |
0.762 |
|
2012 |
Kirby KA, Marchand B, Ong YT, Ndongwe TP, Hachiya A, Michailidis E, Leslie MD, Sietsema DV, Fetterly TL, Dorst CA, Singh K, Wang Z, Parniak MA, Sarafianos SG. Structural and inhibition studies of the RNase H function of xenotropic murine leukemia virus-related virus reverse transcriptase. Antimicrobial Agents and Chemotherapy. 56: 2048-61. PMID 22252812 DOI: 10.1128/Aac.06000-11 |
0.501 |
|
2012 |
Chen YL, Tang J, Kesler MJ, Sham YY, Vince R, Geraghty RJ, Wang Z. The design, synthesis and biological evaluations of C-6 or C-7 substituted 2-hydroxyisoquinoline-1,3-diones as inhibitors of hepatitis C virus. Bioorganic & Medicinal Chemistry. 20: 467-79. PMID 22100256 DOI: 10.1016/J.Bmc.2011.10.058 |
0.762 |
|
2011 |
Tang J, Maddali K, Dreis CD, Sham YY, Vince R, Pommier Y, Wang Z. N-3 Hydroxylation of Pyrimidine-2,4-diones Yields Dual Inhibitors of HIV Reverse Transcriptase and Integrase. Acs Medicinal Chemistry Letters. 2: 63-67. PMID 21499541 DOI: 10.1021/Ml1002162 |
0.751 |
|
2011 |
Tang J, Maddali K, Dreis CD, Sham YY, Vince R, Pommier Y, Wang Z. 6-Benzoyl-3-hydroxypyrimidine-2,4-diones as dual inhibitors of HIV reverse transcriptase and integrase. Bioorganic & Medicinal Chemistry Letters. 21: 2400-2. PMID 21392991 DOI: 10.1016/J.Bmcl.2011.02.069 |
0.765 |
|
2011 |
Tang J, Maddali K, Metifiot M, Sham YY, Vince R, Pommier Y, Wang Z. 3-Hydroxypyrimidine-2,4-diones as an inhibitor scaffold of HIV integrase. Journal of Medicinal Chemistry. 54: 2282-92. PMID 21381765 DOI: 10.1021/Jm1014378 |
0.764 |
|
2010 |
Wang Z, Tang J, Salomon CE, Dreis CD, Vince R. Pharmacophore and structure-activity relationships of integrase inhibition within a dual inhibitor scaffold of HIV reverse transcriptase and integrase. Bioorganic & Medicinal Chemistry. 18: 4202-11. PMID 20576573 DOI: 10.1016/J.Bmc.2010.05.004 |
0.774 |
|
2010 |
Tang J, Maddali K, Pommier Y, Sham YY, Wang Z. Scaffold rearrangement of dihydroxypyrimidine inhibitors of HIV integrase: Docking model revisited. Bioorganic & Medicinal Chemistry Letters. 20: 3275-9. PMID 20457521 DOI: 10.1016/J.Bmcl.2010.04.048 |
0.517 |
|
2008 |
Wang Z, Vince R. Design and synthesis of dual inhibitors of HIV reverse transcriptase and integrase: introducing a diketoacid functionality into delavirdine. Bioorganic & Medicinal Chemistry. 16: 3587-95. PMID 18314335 DOI: 10.1016/J.Bmc.2008.02.007 |
0.758 |
|
2008 |
Wang Z, Vince R. Synthesis of pyrimidine and quinolone conjugates as a scaffold for dual inhibitors of HIV reverse transcriptase and integrase. Bioorganic & Medicinal Chemistry Letters. 18: 1293-6. PMID 18226894 DOI: 10.1016/J.Bmcl.2008.01.025 |
0.75 |
|
2008 |
WANG Z, VINCE R. From RT Inhibitor to RT/IN Dual Inhibitor: An Rational Design Antiviral Research. 78: A51-A51. DOI: 10.1016/J.Antiviral.2008.01.103 |
0.689 |
|
2007 |
Wang Z, Bennett EM, Wilson DJ, Salomon C, Vince R. Rationally designed dual inhibitors of HIV reverse transcriptase and integrase. Journal of Medicinal Chemistry. 50: 3416-9. PMID 17608468 DOI: 10.1021/Jm070512P |
0.747 |
|
2003 |
Rigby JH, Wang Z. Synthesis of highly substituted cyclopentenones via the [4 + 1] cycloaddition of nucleophilic carbenes and vinyl ketenes. Organic Letters. 5: 263-4. PMID 12556167 DOI: 10.1021/Ol0272141 |
0.538 |
|
2002 |
Rigby JH, Wang Z. [4 + 1] cycloaddition of N-heterocyclic carbenes with vinyl isocyanates. Organic Letters. 4: 4289-91. PMID 12443080 DOI: 10.1021/Ol026927G |
0.515 |
|
Show low-probability matches. |