Brandon I. Morinaka, Ph.D. - Publications

Affiliations: 
2011 Chemistry University of California, San Diego, La Jolla, CA 
Area:
Organic chemistry of marine natural products, synthesis, NMR, and biomedical applications

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Phan CS, Chang L, Nguyen TQN, Suarez AFL, Ho XH, Chen H, Koh IYF, Morinaka BI. Substrate Promiscuity of the Triceptide Maturase XncB Leads to Incorporation of Various Amino Acids and Detection of Oxygenated Products. Acs Chemical Biology. PMID 38452396 DOI: 10.1021/acschembio.3c00782  0.32
2024 Suarez AFL, Nguyen TQN, Chang L, Tooh YW, Yong RHS, Leow LC, Koh IYF, Chen H, Koh JWH, Selvanayagam A, Lim V, Tan YE, Agatha I, Winnerdy FR, Morinaka BI. Functional and Promiscuity Studies of Three-Residue Cyclophane Forming Enzymes Show Nonnative C-C Cross-Linked Products and Leader-Dependent Cyclization. Acs Chemical Biology. PMID 38417140 DOI: 10.1021/acschembio.3c00795  0.314
2023 Phan CS, Morinaka BI. Bacterial cyclophane-containing RiPPs from radical SAM enzymes. Natural Product Reports. PMID 38047390 DOI: 10.1039/d3np00030c  0.351
2022 Sugiyama R, Suarez AFL, Morishita Y, Nguyen TQN, Tooh YW, Roslan MNHB, Lo Choy J, Su Q, Goh WY, Gunawan GA, Wong FT, Morinaka BI. The Biosynthetic Landscape of Triceptides Reveals Radical SAM Enzymes That Catalyze Cyclophane Formation on Tyr- and His-Containing Motifs. Journal of the American Chemical Society. 144: 11580-11593. PMID 35729768 DOI: 10.1021/jacs.2c00521  0.401
2022 Hubrich F, Bösch NM, Chepkirui C, Morinaka BI, Rust M, Gugger M, Robinson SL, Vagstad AL, Piel J. Ribosomally derived lipopeptides containing distinct fatty acyl moieties. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35027450 DOI: 10.1073/pnas.2113120119  0.395
2021 Morinaka BI, Schmidt EW, Purushothaman M, Sarkar S, Morita M, Gugger M. Genome mining based discovery of the cyclic peptide tolypamide and TolF, a Ser/Thr forward O-prenyltransferase. Angewandte Chemie (International Ed. in English). PMID 33586286 DOI: 10.1002/anie.202015975  0.319
2020 Nguyen TQN, Tooh YW, Sugiyama R, Nguyen TPD, Purushothaman M, Leow LC, Hanif K, Yong RHS, Agatha I, Winnerdy FR, Gugger M, Phan AT, Morinaka BI. Post-translational formation of strained cyclophanes in bacteria. Nature Chemistry. PMID 32807886 DOI: 10.1038/s41557-020-0519-z  0.356
2020 Mordhorst S, Morinaka BI, Vagstad AL, Piel J. Posttranslationally Acting Arginases Provide a Ribosomal Route to Non-proteinogenic Ornithine Residues in Diverse Peptide Sequences. Angewandte Chemie (International Ed. in English). PMID 32780902 DOI: 10.1002/Anie.202008990  0.567
2020 Bösch NM, Borsa M, Greczmiel U, Morinaka BI, Gugger M, Oxenius A, Vagstad AL, Piel J. Landornamides: Antiviral Ornithine-Containing Ribosomal Peptides Discovered through Genome Mining. Angewandte Chemie (International Ed. in English). PMID 32163654 DOI: 10.1002/Anie.201916321  0.599
2019 Stöckli M, Morinaka BI, Lackner G, Kombrink A, Sieber R, Margot C, Stanley CE, deMello AJ, Piel J, Künzler M. Bacteria-induced production of the antibacterial sesquiterpene lagopodin B in Coprinopsis cinerea. Molecular Microbiology. PMID 31087720 DOI: 10.1111/Mmi.14277  0.564
2018 Morinaka BI, Vagstad AL, Piel J. Radical S-Adenosylmethionine Peptide Epimerases: Detection of Activity and Characterization of d-Amino Acid Products. Methods in Enzymology. 604: 237-257. PMID 29779654 DOI: 10.1016/Bs.Mie.2018.01.033  0.576
2018 Morinaka BI, Lakis E, Verest M, Helf MJ, Scalvenzi T, Vagstad AL, Sims J, Sunagawa S, Gugger M, Piel J. Natural noncanonical protein splicing yields products with diverse β-amino acid residues. Science (New York, N.Y.). 359: 779-782. PMID 29449488 DOI: 10.1126/Science.Aao0157  0.765
2017 Molinski TF, Broaddus CD, Morinaka BI. Liposomal Circular Dichroism (L-CD) of Arenoyl Derivatives of Sphingolipids. Amplification of Cotton Effects in Ordered Lipid Bilayers. Marine Drugs. 15. PMID 29261105 DOI: 10.3390/Md15120352  0.535
2017 Ueoka R, Bortfeld-Miller M, Morinaka BI, Vorholt JA, Piel J. Toblerols: Cyclopropanol-Containing Polyketide Modulators of Antibiosis in Methylobacteria. Angewandte Chemie (International Ed. in English). PMID 29112783 DOI: 10.1002/Anie.201709056  0.556
2017 Moosmann P, Ueoka R, Grauso L, Mangoni A, Morinaka BI, Gugger M, Piel J. Cyanobacterial ent-Sterol-Like Natural Products from a Deviated Ubiquinone Pathway. Angewandte Chemie (International Ed. in English). PMID 28370791 DOI: 10.1002/Anie.201611617  0.603
2017 Freeman MF, Helf MJ, Bhushan A, Morinaka BI, Piel J. Seven enzymes create extraordinary molecular complexity in an uncultivated bacterium. Nature Chemistry. 9: 387-395. PMID 28338684 DOI: 10.1038/Nchem.2666  0.774
2016 Morinaka BI, Verest M, Freeman MF, Gugger M, Piel J. An Orthogonal D2 O-Based Induction System that Provides Insights into d-Amino Acid Pattern Formation by Radical S-Adenosylmethionine Peptide Epimerases. Angewandte Chemie (International Ed. in English). PMID 27958669 DOI: 10.1002/Anie.201609469  0.72
2016 Fuchs SW, Lackner G, Morinaka BI, Morishita Y, Asai T, Riniker S, Piel J. A Lanthipeptide-like N-Terminal Leader Region Guides Peptide Epimerization by Radical SAM Epimerases: Implications for RiPP Evolution. Angewandte Chemie (International Ed. in English). PMID 27584723 DOI: 10.1002/Anie.201602863  0.604
2015 Ueoka R, Uria AR, Reiter S, Mori T, Karbaum P, Peters EE, Helfrich EJ, Morinaka BI, Gugger M, Takeyama H, Matsunaga S, Piel J. Metabolic and evolutionary origin of actin-binding polyketides from diverse organisms. Nature Chemical Biology. 11: 705-12. PMID 26236936 DOI: 10.1038/Nchembio.1870  0.593
2014 Morinaka BI, Vagstad AL, Helf MJ, Gugger M, Kegler C, Freeman MF, Bode HB, Piel J. Radical S-adenosyl methionine epimerases: regioselective introduction of diverse D-amino acid patterns into peptide natural products. Angewandte Chemie (International Ed. in English). 53: 8503-7. PMID 24943072 DOI: 10.1002/Anie.201400478  0.773
2014 Wang X, Morinaka BI, Molinski TF. Structures and solution conformational dynamics of stylissamides G and H from the Bahamian sponge Stylissa caribica. Journal of Natural Products. 77: 625-30. PMID 24576291 DOI: 10.1021/Np400891S  0.578
2013 Pöplau P, Frank S, Morinaka BI, Piel J. An enzymatic domain for the formation of cyclic ethers in complex polyketides Angewandte Chemie - International Edition. 52: 13215-13218. PMID 24307486 DOI: 10.1002/Anie.201307406  0.495
2013 Kampa A, Gagunashvili AN, Gulder TAM, Morinaka BI, Daolio C, Godejohann M, Miao VPW, Piel J, Andrésson OS. Metagenomic natural product discovery in lichen provides evidence for a family of biosynthetic pathways in diverse symbioses Proceedings of the National Academy of Sciences of the United States of America. 110: E3129-E3137. PMID 23898213 DOI: 10.1073/Pnas.1305867110  0.606
2013 Pöplau P, Frank S, Morinaka BI, Piel J. Eine enzymatische Domäne für die Erzeugung cyclischer Ether in komplexen Polyketiden Angewandte Chemie. 125: 13457-13460. DOI: 10.1002/Ange.201307406  0.494
2012 Molinski TF, Morinaka BI. INTEGRATED APPROACHES TO THE CONFIGURATIONAL ASSIGNMENT OF MARINE NATURAL PRODUCTS. Tetrahedron. 68: 9307-9343. PMID 23814320 DOI: 10.1016/J.Tet.2011.12.070  0.543
2012 Freeman MF, Gurgui C, Helf MJ, Morinaka BI, Uria AR, Oldham NJ, Sahl HG, Matsunaga S, Piel J. Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides. Science (New York, N.Y.). 338: 387-90. PMID 22983711 DOI: 10.1126/Science.1226121  0.779
2012 Stout EP, Morinaka BI, Wang YG, Romo D, Molinski TF. De novo synthesis of benzosceptrin C and nagelamide H from 7-15N-oroidin: implications for pyrrole-aminoimidazole alkaloid biosynthesis. Journal of Natural Products. 75: 527-30. PMID 22455452 DOI: 10.1021/Np300051K  0.769
2012 Molinski TF, Reynolds KA, Morinaka BI. Symplocin A, a linear peptide from the Bahamian cyanobacterium Symploca sp. Configurational analysis of N,N-dimethylamino acids by chiral-phase HPLC of naphthacyl esters. Journal of Natural Products. 75: 425-31. PMID 22360587 DOI: 10.1021/Np200861N  0.603
2012 Freeman MF, Gurgui C, Helf MJ, Morinaka BI, Uria AR, Oldham NJ, Sahl HG, Matsunaga S, Piel J. Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides Science. 338: 387-390. DOI: 10.1126/science.1226521  0.662
2012 Piel J, Freeman M, Gurgui C, Helf M, Morinaka B, Wilson M, Mori T, Rueckert C, Steffens U, Takada K, Gernert C, Uria A, Wakimoto T, Abe I, Hentschel U, et al. Chemical surprises from an uncultivated sponge symbiont Planta Medica. 78. DOI: 10.1055/S-0032-1320225  0.774
2011 Morinaka BI, Molinski TF. Mollenyne A, a long-chain chlorodibromohydrin amide from the sponge Spirastrella mollis. Organic Letters. 13: 6338-41. PMID 22087509 DOI: 10.1021/Ol2024778  0.551
2011 Smith AB, Hogan AM, Liu Z, Razler TM, Meis RM, Morinaka BI, Molinski TF. Phorboxazole Synthetic Studies: Design, Synthesis and Biological Evaluation of Phorboxazole A and Hemi-Phorboxazole A Related Analogues. Tetrahedron. 67: 5069-5078. PMID 21811346 DOI: 10.1016/J.Tet.2010.12.043  0.592
2011 Morinaka BI, Molinski TF. Xestoproxamines A-C from Neopetrosia proxima. Assignment of absolute stereostructure of bis-piperidine alkaloids by integrated degradation-CD analysis. Journal of Natural Products. 74: 430-40. PMID 21341726 DOI: 10.1021/Np1008637  0.59
2011 Watts KR, Morinaka BI, Amagata T, Robinson SJ, Tenney K, Bray WM, Gassner NC, Lokey RS, Media J, Valeriote FA, Crews P. Biostructural features of additional jasplakinolide (jaspamide) analogues. Journal of Natural Products. 74: 341-51. PMID 21241058 DOI: 10.1021/Np100721G  0.365
2011 Ko J, Morinaka BI, Molinski TF. Faulknerynes A-C from a Bahamian sponge Diplastrella sp.: stereoassignment by critical application of two exciton coupled CD methods. The Journal of Organic Chemistry. 76: 894-901. PMID 21218782 DOI: 10.1021/Jo102188Q  0.562
2010 Morinaka BI, Pawlik JR, Molinski TF. Amaranzoles B-F, imidazole-2-carboxy steroids from the marine sponge Phorbas amaranthus. C24-N- and C24-O-analogues from a divergent oxidative biosynthesis. The Journal of Organic Chemistry. 75: 2453-60. PMID 20235564 DOI: 10.1021/Jo1000324  0.578
2010 Robinson SJ, Morinaka BI, Amagata T, Tenney K, Bray WM, Gassner NC, Scott Lokey R, Crews P. New structures and bioactivity properties of jasplakinolide (jaspamide) analogues from marine sponges Journal of Medicinal Chemistry. 53: 1651-1661. PMID 20121114 DOI: 10.1021/Jm9013554  0.401
2010 Wang YG, Morinaka BI, Reyes JC, Wolff JJ, Romo D, Molinski TF. Synthesis of 7-(15)N-Oroidin and evaluation of utility for biosynthetic studies of pyrrole-imidazole alkaloids by microscale (1)H-(15)N HSQC and FTMS. Journal of Natural Products. 73: 428-34. PMID 20095632 DOI: 10.1021/Np900638E  0.562
2010 Lievens SC, Morinaka BI, Molinski TF. Stereochemical elucidation of new sagittamides CF from a didemnid ascidian Australian Journal of Chemistry. 63: 935-941. DOI: 10.1071/Ch10059  0.752
2009 Dalisay DS, Morinaka BI, Skepper CK, Molinski TF. A tetrachloro polyketide hexahydro-1H-isoindolone, muironolide A, from the marine sponge Phorbas sp. natural products at the nanomole scale. Journal of the American Chemical Society. 131: 7552-3. PMID 19453148 DOI: 10.1021/Ja9024929  0.775
2009 Morinaka BI, Pawlik JR, Molinski TF. Amaroxocanes A and B: sulfated dimeric sterols defend the Caribbean coral reef sponge Phorbas amaranthus from fish predators. Journal of Natural Products. 72: 259-64. PMID 19143510 DOI: 10.1021/Np800652V  0.577
2008 Morinaka BI, Molinski TF. Exciton coupling circular dichroism of an allylic N-imidazolyl group in amaranzole A, a marine natural product from Phorbas amaranthus. Chirality. 20: 1066-70. PMID 18690668 DOI: 10.1002/Chir.20636  0.563
2008 Molinski T, Dalisay D, Morinaka B, Quach T. Configuration of natural products: Liposomal circular dichroism (LCD) for acyclic stereocenters Planta Medica. 74. DOI: 10.1055/s-0028-1083949  0.509
2007 Morinaka BI, Masuno MN, Pawlik JR, Molinski TF. Amaranzole A, a new N-imidazolyl steroid from Phorbas amaranthus. Organic Letters. 9: 5219-22. PMID 17990891 DOI: 10.1021/Ol702325E  0.76
2007 Johnson TA, Tenney K, Cichewicz RH, Morinaka BI, White KN, Amagata T, Subramanian B, Media J, Mooberry SL, Valeriote FA, Crews P. Sponge-derived fijianolide polyketide class: further evaluation of their structural and cytotoxicity properties. Journal of Medicinal Chemistry. 50: 3795-803. PMID 17622130 DOI: 10.1021/Jm070410Z  0.356
2007 Morinaka BI, Skepper CK, Molinski TF. Ene-yne tetrahydrofurans from the sponge Xestospongia muta. exploiting a weak CD effect for assignment of configuration. Organic Letters. 9: 1975-8. PMID 17439137 DOI: 10.1021/Ol0705696  0.766
2006 Amagata T, Morinaka BI, Amagata A, Tenney K, Valeriote FA, Lobkovsky E, Clardy J, Crews P. A chemical study of cyclic depsipeptides produced by a sponge-derived fungus Journal of Natural Products. 69: 1560-1565. PMID 17125221 DOI: 10.1021/Np060178K  0.391
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