Juan C. Leza - Publications

Affiliations: 
Complutense University of Madrid, Madrid, Comunidad de Madrid, Spain 
Area:
psychological stress, oxidative/nitrosative damage, neuroinflammation

161 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Tendilla-Beltrán H, Meneses-Prado S, Antonio Vázquez-Roque R, Tapia-Rodríguez M, Judith Vázquez-Hernández A, Coatl-Cuaya H, Martín-Hernández D, MacDowell KS, Garcés-Ramírez L, Leza JC, Flores G. Risperidone ameliorates prefrontal cortex neural atrophy and oxidative/nitrosative stress in brain and peripheral blood of rats with neonatal ventral hippocampus lesion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31519825 DOI: 10.1523/JNEUROSCI.1249-19.2019  0.84
2019 Caso JR, Graell M, Navalón A, MacDowell KS, Gutiérrez S, Soto M, Leza JC, Carrasco JL, Marsá MD. Dysfunction of inflammatory pathways in adolescent female patients with anorexia nervosa. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 109727. PMID 31398429 DOI: 10.1016/j.pnpbp.2019.109727  0.8
2019 Gutiérrez IL, González-Prieto M, Caso JR, García-Bueno B, Leza JC, Madrigal JLM. Reboxetine Treatment Reduces Neuroinflammation and Neurodegeneration in the 5xFAD Mouse Model of Alzheimer's Disease: Role of CCL2. Molecular Neurobiology. PMID 31297718 DOI: 10.1007/s12035-019-01695-6  0.8
2019 Casquero-Veiga M, García-García D, MacDowell KS, Pérez-Caballero L, Torres-Sánchez S, Fraguas D, Berrocoso E, Leza JC, Arango C, Desco M, Soto-Montenegro ML. Risperidone administered during adolescence induced metabolic, anatomical and inflammatory/oxidative changes in adult brain: A PET and MRI study in the maternal immune stimulation animal model. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 31229322 DOI: 10.1016/j.euroneuro.2019.05.002  0.8
2019 Martín-Hernández D, Pereira MP, Tendilla-Beltrán H, Madrigal JLM, García-Bueno B, Leza JC, Caso JR. Modulation of Monoaminergic Systems by Antidepressants in the Frontal Cortex of Rats After Chronic Mild Stress Exposure. Molecular Neurobiology. PMID 31054078 DOI: 10.1007/s12035-019-1619-x  0.84
2018 Martín-Hernández D, Caso JR, Javier Meana J, Callado LF, Madrigal JLM, García-Bueno B, Leza JC. Intracellular inflammatory and antioxidant pathways in postmortem frontal cortex of subjects with major depression: effect of antidepressants. Journal of Neuroinflammation. 15: 251. PMID 30180869 DOI: 10.1186/s12974-018-1294-2  0.8
2018 Fraguas D, Díaz-Caneja CM, Ayora M, Hernández-Álvarez F, Rodríguez-Quiroga A, Recio S, Leza JC, Arango C. Oxidative Stress and Inflammation in First-Episode Psychosis: A Systematic Review and Meta-analysis. Schizophrenia Bulletin. PMID 30169868 DOI: 10.1093/schbul/sby125  0.36
2018 Gutiérrez IL, González-Prieto M, García-Bueno B, Caso JR, Leza JC, Madrigal JLM. Alternative Method to Detect Neuronal Degeneration and Amyloid β Accumulation in Free-Floating Brain Sections With Fluoro-Jade. Asn Neuro. 10: 1759091418784357. PMID 29950099 DOI: 10.1177/1759091418784357  0.8
2018 Martín-Hernández D, Tendilla-Beltrán H, Madrigal JLM, García-Bueno B, Leza JC, Caso JR. Chronic Mild Stress Alters Kynurenine Pathways Changing the Glutamate Neurotransmission in Frontal Cortex of Rats. Molecular Neurobiology. PMID 29725904 DOI: 10.1007/s12035-018-1096-7  0.84
2017 Vargas-Caraveo A, Sayd A, Maus SR, Caso JR, Madrigal JLM, García-Bueno B, Leza JC. Lipopolysaccharide enters the rat brain by a lipoprotein-mediated transport mechanism in physiological conditions. Scientific Reports. 7: 13113. PMID 29030613 DOI: 10.1038/s41598-017-13302-6  0.8
2017 MacDowell KS, Pinacho R, Leza JC, Costa J, Ramos B, Bueno BG. Differential regulation of the TLR4 signalling pathway in post-mortem prefrontal cortex and cerebellum in chronic schizophrenia: Relationship with SP transcription factors. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 28803924 DOI: 10.1016/j.pnpbp.2017.08.005  0.8
2016 MacDowell KS, Munarriz-Cuezva E, Caso JR, Madrigal JL, Zabala A, Meana JJ, García-Bueno B, Leza JC. Paliperidone reverts Toll-like receptor 3 signaling pathway activation and cognitive deficits in a maternal immune activation mouse model of schizophrenia. Neuropharmacology. 116: 196-207. PMID 28039001 DOI: 10.1016/j.neuropharm.2016.12.025  0.8
2016 Madrigal JL, Caso JR, García-Bueno B, Gutiérrez IL, Leza JC. Noradrenaline induces CX3CL1 production and release by neurons. Neuropharmacology. PMID 27923568 DOI: 10.1016/j.neuropharm.2016.12.001  0.8
2016 MacDowell KS, Caso JR, Martín-Hernández D, Moreno BM, Madrigal JL, Micó JA, Leza JC, García-Bueno B. The Atypical Antipsychotic Paliperidone Regulates Endogenous Antioxidant/Anti-Inflammatory Pathways in Rat Models of Acute and Chronic Restraint Stress. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 27233514 DOI: 10.1007/s13311-016-0438-2  0.84
2016 García-Bueno B, Gassó P, MacDowell KS, Callado LF, Mas S, Bernardo M, Lafuente A, Meana JJ, Leza JC. Evidence of activation of the Toll-like receptor-4 proinflammatory pathway in patients with schizophrenia. Journal of Psychiatry & Neuroscience : Jpn. 41: 150195. PMID 27070349 DOI: 10.1503/jpn.150195  0.8
2016 MacDowell KS, Sayd A, García-Bueno B, Caso JR, Madrigal JL, Leza JC. Effects of the antipsychotic paliperidone on stress-induced changes in the endocannabinoid system in rat prefrontal cortex. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 1-14. PMID 26987678 DOI: 10.3109/15622975.2016.1151075  0.8
2016 García Bueno B, Caso JR, Madrigal JL, Leza JC. Innate immune receptor Toll-like receptor 4 signalling in neuropsychiatric diseases. Neuroscience and Biobehavioral Reviews. PMID 26905767 DOI: 10.1016/j.neubiorev.2016.02.013  0.8
2016 Bioque M, Cabrera B, García-Bueno B, Mac-Dowell KS, Torrent C, Saiz PA, Parellada M, González-Pinto A, Lobo A, Leza JC, Bernardo M. Dysregulated peripheral endocannabinoid system signaling is associated with cognitive deficits in first-episode psychosis. Journal of Psychiatric Research. 75: 14-21. PMID 26783729 DOI: 10.1016/j.jpsychires.2016.01.002  0.56
2015 Besga A, Gonzalez I, Echeburua E, Savio A, Ayerdi B, Chyzhyk D, Madrigal JL, Leza JC, Graña M, Gonzalez-Pinto AM. Discrimination between Alzheimer's Disease and Late Onset Bipolar Disorder Using Multivariate Analysis. Frontiers in Aging Neuroscience. 7: 231. PMID 26696883 DOI: 10.3389/fnagi.2015.00231  0.72
2015 Martín-Hernández D, Caso JR, Bris ÁG, Maus SR, Madrigal JL, García-Bueno B, MacDowell KS, Alou L, Gómez-Lus ML, Leza JC. Bacterial translocation affects intracellular neuroinflammatory pathways in a depression-like model in rats. Neuropharmacology. PMID 26686392 DOI: 10.1016/j.neuropharm.2015.12.003  0.56
2015 Martín-Hernández D, Bris ÁG, MacDowell KS, García-Bueno B, Madrigal JL, Leza JC, Caso JR. Modulation of the antioxidant Nuclear Factor (erythroid 2-derived)-like 2 pathway by antidepressants in rats. Neuropharmacology. PMID 26686388 DOI: 10.1016/j.neuropharm.2015.11.029  0.84
2015 Romero-Grimaldi C, Berrocoso E, Alba-Delgado C, Madrigal JL, Perez-Nievas BG, Leza JC, Mico JA. Stress Increases the Negative Effects of Chronic Pain on Hippocampal Neurogenesis. Anesthesia and Analgesia. 121: 1078-88. PMID 26218865 DOI: 10.1213/ANE.0000000000000838  0.56
2015 Martinez-Cengotitabengoa M, MacDowell KS, Alberich S, Diaz FJ, Garcia-Bueno B, Rodriguez-Jimenez R, Bioque M, Berrocoso E, Parellada M, Lobo A, Saiz PA, Matute C, Bernardo M, Gonzalez-Pinto A, Leza JC, et al. BDNF and NGF Signalling in Early Phases of Psychosis: Relationship With Inflammation and Response to Antipsychotics After 1 Year. Schizophrenia Bulletin. PMID 26130821 DOI: 10.1093/schbul/sbv078  0.56
2015 Ferrés-Coy A, Galofré M, Pilar-Cuéllar F, Vidal R, Paz V, Ruiz-Bronchal E, Campa L, Pazos Á, Caso JR, Leza JC, Alvarado G, Montefeltro A, Valdizán EM, Artigas F, Bortolozzi A. Therapeutic antidepressant potential of a conjugated siRNA silencing the serotonin transporter after intranasal administration. Molecular Psychiatry. PMID 26100539 DOI: 10.1038/mp.2015.80  0.8
2015 Leza JC, García-Bueno B, Bioque M, Arango C, Parellada M, Do K, O'Donnell P, Bernardo M. Inflammation in schizophrenia: A question of balance. Neuroscience and Biobehavioral Reviews. 55: 612-26. PMID 26092265 DOI: 10.1016/j.neubiorev.2015.05.014  0.72
2015 Maes M, Nowak G, Caso JR, Leza JC, Song C, Kubera M, Klein H, Galecki P, Noto C, Glaab E, Balling R, Berk M. Toward Omics-Based, Systems Biomedicine, and Path and Drug Discovery Methodologies for Depression-Inflammation Research. Molecular Neurobiology. PMID 25934103 DOI: 10.1007/s12035-015-9183-5  0.56
2015 Rapado-Castro M, Pazos Á, Fañanás L, Bernardo M, Ayuso-Mateos JL, Leza JC, Berrocoso E, de Arriba J, Roldán L, Sanjuán J, Pérez V, Haro JM, Palomo T, Valdizan EM, Micó JA, et al. Building up careers in translational neuroscience and mental health research: Education and training in the Centre for Biomedical Research in Mental Health. Revista De Psiquiatrí́a Y Salud Mental. 8: 65-74. PMID 25682021 DOI: 10.1016/j.rpsm.2014.09.003  0.56
2015 Sayd A, Antón M, Alén F, Caso JR, Pavón J, Leza JC, Rodríguez de Fonseca F, García-Bueno B, Orio L. Systemic administration of oleoylethanolamide protects from neuroinflammation and anhedonia induced by LPS in rats. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25548106 DOI: 10.1093/ijnp/pyu111  0.56
2015 MacDowell KS, Caso JR, Martín-Hernández D, Madrigal JI, Leza JC, García-Bueno B. Paliperidone prevents brain toll-like receptor 4 pathway activation and neuroinflammation in rat models of acute and chronic restraint stress. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25522409 DOI: 10.1093/ijnp/pyu070  0.8
2015 Ferrés-Coy A, Galofré M, Pilar-Cuéllar F, Vidal R, Paz V, Ruiz-Bronchal E, Campa L, Pazos, Caso JR, Leza JC, Alvarado G, Montefeltro A, Valdizán EM, Artigas F, Bortolozzi A. Therapeutic antidepressant potential of a conjugated siRNA silencing the serotonin transporter after intranasal administration Molecular Psychiatry. DOI: 10.1038/mp.2015.80  0.56
2015 Palma-Gudiel H, Córdova-Palomera A, Leza JC, Fañanás L. Glucocorticoid receptor gene (NR3C1) methylation processes as mediators of early adversity in stress-related disorders causality: A critical review Neuroscience and Biobehavioral Reviews. 55: 520-535. DOI: 10.1016/j.neubiorev.2015.05.016  0.56
2015 Leza JC, Bueno B, Bioque M, Arango C, Parellada M, Do K, O'Donnell P, Bernardo M. Inflammation in schizophrenia: A question of balance Neuroscience and Biobehavioral Reviews. 55: 612-626. DOI: 10.1016/j.neubiorev.2015.05.014  0.56
2014 García-Bueno B, Bioque M, MacDowell KS, Santabárbara J, Martínez-Cengotitabengoa M, Moreno C, Sáiz PA, Berrocoso E, Gassó P, Fe Barcones M, González-Pinto A, Parellada M, Bobes J, Micó JA, Bernardo M, ... Leza JC, et al. Pro-/antiinflammatory dysregulation in early psychosis: results from a 1-year follow-up study. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25577666 DOI: 10.1093/ijnp/pyu037  0.56
2014 Córdova-Palomera A, Alemany S, Fatjó-Vilas M, Goldberg X, Leza JC, González-Pinto A, Nenadic I, Fañanás L. Birth weight, working memory and epigenetic signatures in IGF2 and related genes: a MZ twin study. Plos One. 9: e103639. PMID 25171170 DOI: 10.1371/journal.pone.0103639  0.56
2014 Martínez-Cengotitabengoa M, Micó JA, Arango C, Castro-Fornieles J, Graell M, Payá B, Leza JC, Zorrilla I, Parellada M, López MP, Baeza I, Moreno C, Rapado-Castro M, González-Pinto A. Basal low antioxidant capacity correlates with cognitive deficits in early onset psychosis. A 2-year follow-up study. Schizophrenia Research. 156: 23-9. PMID 24768133 DOI: 10.1016/j.schres.2014.03.025  0.56
2014 Zoppi S, Madrigal JL, Caso JR, García-Gutiérrez MS, Manzanares J, Leza JC, García-Bueno B. Regulatory role of the cannabinoid CB2 receptor in stress-induced neuroinflammation in mice. British Journal of Pharmacology. 171: 2814-26. PMID 24467609 DOI: 10.1111/bph.12607  0.56
2014 Gárate I, García-Bueno B, Madrigal JL, Caso JR, Alou L, Gómez-Lus ML, Leza JC. Toll-like 4 receptor inhibitor TAK-242 decreases neuroinflammation in rat brain frontal cortex after stress. Journal of Neuroinflammation. 11: 8. PMID 24410883 DOI: 10.1186/1742-2094-11-8  0.56
2014 Perez-Caballero L, Pérez-Egea R, Romero-Grimaldi C, Puigdemont D, Molet J, Caso JR, Mico JA, Pérez V, Leza JC, Berrocoso E. Early responses to deep brain stimulation in depression are modulated by anti-inflammatory drugs. Molecular Psychiatry. 19: 607-14. PMID 23711979 DOI: 10.1038/mp.2013.63  0.56
2014 García-Bueno B, Bioque M, Mac-Dowell KS, Barcones MF, Martínez-Cengotitabengoa M, Pina-Camacho L, Rodríguez-Jiménez R, Sáiz PA, Castro C, Lafuente A, Santabárbara J, González-Pinto A, Parellada M, Rubio G, García-Portilla MP, ... ... Leza JC, et al. Pro-/anti-inflammatory dysregulation in patients with first episode of psychosis: toward an integrative inflammatory hypothesis of schizophrenia. Schizophrenia Bulletin. 40: 376-87. PMID 23486748 DOI: 10.1093/schbul/sbt001  0.56
2013 Hinojosa AE, Caso JR, García-Bueno B, Leza JC, Madrigal JL. Dual effects of noradrenaline on astroglial production of chemokines and pro-inflammatory mediators. Journal of Neuroinflammation. 10: 81. PMID 23837880 DOI: 10.1186/1742-2094-10-81  0.56
2013 Bioque M, García-Bueno B, Macdowell KS, Meseguer A, Saiz PA, Parellada M, Gonzalez-Pinto A, Rodriguez-Jimenez R, Lobo A, Leza JC, Bernardo M. Peripheral endocannabinoid system dysregulation in first-episode psychosis. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2568-77. PMID 23822951 DOI: 10.1038/npp.2013.165  0.56
2013 MacDowell KS, Díaz-Marsá M, Güemes I, Rodríguez A, Leza JC, Carrasco JL. Inflammatory activation and cholinergic anti-inflammatory system in eating disorders. Brain, Behavior, and Immunity. 32: 33-9. PMID 23624297 DOI: 10.1016/j.bbi.2013.04.006  0.56
2013 Urigüen L, Gil-Pisa I, Munarriz-Cuezva E, Berrocoso E, Pascau J, Soto-Montenegro ML, Gutiérrez-Adán A, Pintado B, Madrigal JL, Castro E, Sánchez-Blázquez P, Ortega JE, Guerrero MJ, Ferrer-Alcon M, García-Sevilla JA, ... ... Leza JC, et al. Behavioral, neurochemical and morphological changes induced by the overexpression of munc18-1a in brain of mice: relevance to schizophrenia. Translational Psychiatry. 3: e221. PMID 23340504 DOI: 10.1038/tp.2012.149  0.56
2013 Gárate I, Garcia-Bueno B, Madrigal JL, Caso JR, Alou L, Gomez-Lus ML, Micó JA, Leza JC. Stress-induced neuroinflammation: role of the Toll-like receptor-4 pathway. Biological Psychiatry. 73: 32-43. PMID 22906518 DOI: 10.1016/j.biopsych.2012.07.005  0.56
2013 MacDowell KS, García-Bueno B, Madrigal JL, Parellada M, Arango C, Micó JA, Leza JC. Risperidone normalizes increased inflammatory parameters and restores anti-inflammatory pathways in a model of neuroinflammation. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 121-35. PMID 22176740 DOI: 10.1017/S1461145711001775  0.56
2012 Gonzalez-Pinto A, Martinez-Cengotitabengoa M, Arango C, Baeza I, Otero-Cuesta S, Graell-Berna M, Soutullo C, Leza JC, Micó JA. Antioxidant defense system and family environment in adolescents with family history of psychosis. Bmc Psychiatry. 12: 200. PMID 23158023 DOI: 10.1186/1471-244X-12-200  0.56
2012 Díaz-Marsá M, Macdowell KS, Guemes I, Rubio V, Carrasco JL, Leza JC. Activation of the cholinergic anti-inflammatory system in peripheral blood mononuclear cells from patients with borderline personality disorder. Journal of Psychiatric Research. 46: 1610-7. PMID 23083519 DOI: 10.1016/j.jpsychires.2012.09.009  0.56
2012 Bravo L, Mico JA, Rey-Brea R, Pérez-Nievas B, Leza JC, Berrocoso E. Depressive-like states heighten the aversion to painful stimuli in a rat model of comorbid chronic pain and depression. Anesthesiology. 117: 613-25. PMID 22846678 DOI: 10.1097/ALN.0b013e3182657b3e  0.56
2012 Martínez-Cengotitabengoa M, Mac-Dowell KS, Leza JC, Micó JA, Fernandez M, Echevarría E, Sanjuan J, Elorza J, González-Pinto A. Cognitive impairment is related to oxidative stress and chemokine levels in first psychotic episodes. Schizophrenia Research. 137: 66-72. PMID 22445462 DOI: 10.1016/j.schres.2012.03.004  0.56
2012 Fraguas D, Gonzalez-Pinto A, Micó JA, Reig S, Parellada M, Martínez-Cengotitabengoa M, Castro-Fornieles J, Rapado-Castro M, Baeza I, Janssen J, Desco M, Leza JC, Arango C. Decreased glutathione levels predict loss of brain volume in children and adolescents with first-episode psychosis in a two-year longitudinal study. Schizophrenia Research. 137: 58-65. PMID 22365149 DOI: 10.1016/j.schres.2012.01.040  0.56
2012 Parellada M, Moreno C, Mac-Dowell K, Leza JC, Giraldez M, Bailón C, Castro C, Miranda-Azpiazu P, Fraguas D, Arango C. Plasma antioxidant capacity is reduced in Asperger syndrome. Journal of Psychiatric Research. 46: 394-401. PMID 22225920 DOI: 10.1016/j.jpsychires.2011.10.004  0.56
2012 Zoppi S, Madrigal JL, Pérez-Nievas BG, Marín-Jiménez I, Caso JR, Alou L, García-Bueno B, Colón A, Manzanares J, Gómez-Lus ML, Menchén L, Leza JC. Endogenous cannabinoid system regulates intestinal barrier function in vivo through cannabinoid type 1 receptor activation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 302: G565-71. PMID 22135307 DOI: 10.1152/ajpgi.00158.2011  0.56
2012 Ortega-Álvaro A, Berrocoso E, Rey-Brea R, Leza JC, Mico JA. Comparison of the antinociceptive effects of ibuprofen arginate and ibuprofen in rat models of inflammatory and neuropathic pain. Life Sciences. 90: 13-20. PMID 22036619 DOI: 10.1016/j.lfs.2011.10.002  0.56
2012 Márquez L, García-Bueno B, Madrigal JL, Leza JC. Mangiferin decreases inflammation and oxidative damage in rat brain after stress. European Journal of Nutrition. 51: 729-39. PMID 21986672 DOI: 10.1007/s00394-011-0252-x  0.56
2012 García-Gutiérrez MS, García-Bueno B, Zoppi S, Leza JC, Manzanares J. Chronic blockade of cannabinoid CB2 receptors induces anxiolytic-like actions associated with alterations in GABA(A) receptors. British Journal of Pharmacology. 165: 951-64. PMID 21838753 DOI: 10.1111/j.1476-5381.2011.01625.x  0.56
2011 Gárate I, García-Bueno B, Madrigal JL, Bravo L, Berrocoso E, Caso JR, Micó JA, Leza JC. Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression. Journal of Neuroinflammation. 8: 151. PMID 22053929 DOI: 10.1186/1742-2094-8-151  0.56
2011 Hinojosa AE, García-Bueno B, Leza JC, Madrigal JL. Regulation of CCL2/MCP-1 production in astrocytes by desipramine and atomoxetine: involvement of α2 adrenergic receptors. Brain Research Bulletin. 86: 326-33. PMID 21963947 DOI: 10.1016/j.brainresbull.2011.09.014  0.56
2011 Hinojosa AE, Garcia-Bueno B, Leza JC, Madrigal JL. CCL2/MCP-1 modulation of microglial activation and proliferation. Journal of Neuroinflammation. 8: 77. PMID 21729288 DOI: 10.1186/1742-2094-8-77  0.56
2011 Martínez-Gras I, Pérez-Nievas BG, García-Bueno B, Madrigal JL, Andrés-Esteban E, Rodríguez-Jiménez R, Hoenicka J, Palomo T, Rubio G, Leza JC. The anti-inflammatory prostaglandin 15d-PGJ2 and its nuclear receptor PPARgamma are decreased in schizophrenia. Schizophrenia Research. 128: 15-22. PMID 21334179 DOI: 10.1016/j.schres.2011.01.018  0.56
2011 González C, Herradón E, Abalo R, Vera G, Pérez-Nievas BG, Leza JC, Martín MI, López-Miranda V. Cannabinoid/agonist WIN 55,212-2 reduces cardiac ischaemia–reperfusion injury in Zucker diabetic fatty rats: role of CB2 receptors and iNOS/eNOS. Diabetes/Metabolism Research and Reviews. 27: 331-40. PMID 21309057 DOI: 10.1002/dmrr.1176  0.56
2011 Zoppi S, Pérez Nievas BG, Madrigal JL, Manzanares J, Leza JC, García-Bueno B. Regulatory role of cannabinoid receptor 1 in stress-induced excitotoxicity and neuroinflammation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 805-18. PMID 21150911 DOI: 10.1038/npp.2010.214  0.56
2011 Perez Nievas BG, Hammerschmidt T, Kummer MP, Terwel D, Leza JC, Heneka MT. Restraint stress increases neuroinflammation independently of amyloid β levels in amyloid precursor protein/PS1 transgenic mice. Journal of Neurochemistry. 116: 43-52. PMID 21044080 DOI: 10.1111/j.1471-4159.2010.07083.x  0.56
2011 Pérez-Rial S, García-Gutiérrez MS, Molina JA, Pérez-Nievas BG, Ledent C, Leiva C, Leza JC, Manzanares J. Increased vulnerability to 6-hydroxydopamine lesion and reduced development of dyskinesias in mice lacking CB1 cannabinoid receptors. Neurobiology of Aging. 32: 631-45. PMID 19419794 DOI: 10.1016/j.neurobiolaging.2009.03.017  0.56
2010 Márquez L, Pérez-Nievas BG, Gárate I, García-Bueno B, Madrigal JL, Menchén L, Garrido G, Leza JC. Anti-inflammatory effects of Mangifera indica L. extract in a model of colitis. World Journal of Gastroenterology : Wjg. 16: 4922-31. PMID 20954278 DOI: 10.3748/wjg.v16.i39.4922  0.56
2010 Pérez-Nievas BG, García-Bueno B, Madrigal JL, Leza JC. Chronic immobilisation stress ameliorates clinical score and neuroinflammation in a MOG-induced EAE in Dark Agouti rats: mechanisms implicated. Journal of Neuroinflammation. 7: 60. PMID 20929574 DOI: 10.1186/1742-2094-7-60  0.56
2010 García-Bueno B, Pérez-Nievas BG, Leza JC. Is there a role for the nuclear receptor PPARγ in neuropsychiatric diseases? The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 13: 1411-29. PMID 20800014 DOI: 10.1017/S1461145710000970  0.56
2010 Madrigal JL, Garcia-Bueno B, Hinojosa AE, Polak P, Feinstein DL, Leza JC. Regulation of MCP-1 production in brain by stress and noradrenaline-modulating drugs. Journal of Neurochemistry. 113: 543-51. PMID 20132473 DOI: 10.1111/j.1471-4159.2010.06623.x  0.56
2010 Pérez-Nievas BG, Madrigal JL, García-Bueno B, Zoppi S, Leza JC. Corticosterone basal levels and vulnerability to LPS-induced neuroinflammation in the rat brain. Brain Research. 1315: 159-68. PMID 20026014 DOI: 10.1016/j.brainres.2009.12.014  0.56
2009 Martinez-Gras I, Rubio G, del Manzano BA, Rodriguez-Jimenez R, Garcia-Sanchez F, Bagney A, Leza JC, Borrell J. The relationship between prepulse inhibition and general psychopathology in patients with schizophrenia treated with long-acting risperidone. Schizophrenia Research. 115: 215-21. PMID 19846280 DOI: 10.1016/j.schres.2009.09.035  0.56
2009 Saiz PA, Garcia-Portilla MP, Florez G, Corcoran P, Arango C, Morales B, Leza JC, Alvarez S, Díaz EM, Alvarez V, Coto E, Nogueiras L, Bobes J. Polymorphisms of the IL-1 gene complex are associated with alcohol dependence in Spanish Caucasians: data from an association study. Alcoholism, Clinical and Experimental Research. 33: 2147-53. PMID 19764937 DOI: 10.1111/j.1530-0277.2009.01058.x  0.56
2009 Caso JR, Hurtado O, Pereira MP, García-Bueno B, Menchén L, Alou L, Gómez-Lus ML, Moro MA, Lizasoain I, Leza JC. Colonic bacterial translocation as a possible factor in stress-worsening experimental stroke outcome. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 296: R979-85. PMID 19193944 DOI: 10.1152/ajpregu.90825.2008  0.56
2009 Madrigal JL, Leza JC, Polak P, Kalinin S, Feinstein DL. Astrocyte-derived MCP-1 mediates neuroprotective effects of noradrenaline. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 263-7. PMID 19129402 DOI: 10.1523/JNEUROSCI.4926-08.2009  0.56
2008 Munhoz CD, García-Bueno B, Madrigal JL, Lepsch LB, Scavone C, Leza JC. Stress-induced neuroinflammation: mechanisms and new pharmacological targets. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 41: 1037-46. PMID 19148364  0.56
2008 Caso JR, Leza JC, Menchén L. The effects of physical and psychological stress on the gastro-intestinal tract: lessons from animal models. Current Molecular Medicine. 8: 299-312. PMID 18537637 DOI: 10.2174/156652408784533751  0.56
2008 Leza JC, Menchén L. Stress-induced deleterious consequences in the gastrointestinal tract. Current Molecular Medicine. 8: 244-6. PMID 18537631 DOI: 10.2174/156652408784533814  0.56
2008 García-Bueno B, Leza JC. [Inflammatory/anti-inflammatory mechanisms in the brain following exposure to stress]. Revista De Neurologia. 46: 675-83. PMID 18509827  0.56
2008 García-Bueno B, Caso JR, Leza JC. Stress as a neuroinflammatory condition in brain: damaging and protective mechanisms. Neuroscience and Biobehavioral Reviews. 32: 1136-51. PMID 18468686 DOI: 10.1016/j.neubiorev.2008.04.001  0.56
2008 Caso JR, Pradillo JM, Hurtado O, Leza JC, Moro MA, Lizasoain I. Toll-like receptor 4 is involved in subacute stress-induced neuroinflammation and in the worsening of experimental stroke. Stroke; a Journal of Cerebral Circulation. 39: 1314-20. PMID 18309167 DOI: 10.1161/STROKEAHA.107.498212  0.56
2008 Fernández-Durango R, Fernández-Martínez A, García-Feijoo J, Castillo A, de la Casa JM, García-Bueno B, Pérez-Nievas BG, Fernández-Cruz A, Leza JC. Expression of nitrotyrosine and oxidative consequences in the trabecular meshwork of patients with primary open-angle glaucoma. Investigative Ophthalmology & Visual Science. 49: 2506-11. PMID 18296660 DOI: 10.1167/iovs.07-1363  0.56
2008 García-Bueno B, Madrigal JL, Pérez-Nievas BG, Leza JC. Stress mediators regulate brain prostaglandin synthesis and peroxisome proliferator-activated receptor-gamma activation after stress in rats. Endocrinology. 149: 1969-78. PMID 18079203 DOI: 10.1210/en.2007-0482  0.56
2007 Pérez-Nievas BG, García-Bueno B, Caso JR, Menchén L, Leza JC. Corticosterone as a marker of susceptibility to oxidative/nitrosative cerebral damage after stress exposure in rats. Psychoneuroendocrinology. 32: 703-11. PMID 17561353 DOI: 10.1016/j.psyneuen.2007.04.011  0.56
2007 Ponferrada A, Caso JR, Alou L, Colón A, Sevillano D, Moro MA, Lizasoain I, Menchén P, Gómez-Lus ML, Lorenzo P, Cos E, Leza JC, Menchén L. The role of PPARgamma on restoration of colonic homeostasis after experimental stress-induced inflammation and dysfunction. Gastroenterology. 132: 1791-803. PMID 17484875 DOI: 10.1053/j.gastro.2007.02.032  0.56
2007 Caso JR, Moro MA, Lorenzo P, Lizasoain I, Leza JC. Involvement of IL-1beta in acute stress-induced worsening of cerebral ischaemia in rats. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 17: 600-7. PMID 17363226 DOI: 10.1016/j.euroneuro.2007.02.009  0.56
2007 García-Bueno B, Caso JR, Pérez-Nievas BG, Lorenzo P, Leza JC. Effects of peroxisome proliferator-activated receptor gamma agonists on brain glucose and glutamate transporters after stress in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1251-60. PMID 17119541 DOI: 10.1038/sj.npp.1301252  0.56
2006 Madrigal JL, García-Bueno B, Caso JR, Pérez-Nievas BG, Leza JC. Stress-induced oxidative changes in brain. Cns & Neurological Disorders Drug Targets. 5: 561-8. PMID 17073658  0.56
2006 Caso JR, Lizasoain I, Lorenzo P, Moro MA, Leza JC. The role of tumor necrosis factor-alpha in stress-induced worsening of cerebral ischemia in rats. Neuroscience. 142: 59-69. PMID 16844305 DOI: 10.1016/j.neuroscience.2006.06.009  0.56
2006 Comabella M, Romera C, Camiña M, Perkal H, Moro MA, Leza JC, Lizasoain I, Castillo M, Montalban X. TNF-alpha converting enzyme (TACE) protein expression in different clinical subtypes of multiple sclerosis. Journal of Neurology. 253: 701-6. PMID 16511637 DOI: 10.1007/s00415-006-0090-6  0.56
2006 Leza JC. Editorial Cns and Neurological Disorders - Drug Targets. 5: 481-483. DOI: 10.2174/187152706778559291  0.56
2005 Cárdenas A, Moro MA, Hurtado O, Leza JC, Lizasoain I. Dual role of nitric oxide in adult neurogenesis. Brain Research. Brain Research Reviews. 50: 1-6. PMID 16291071 DOI: 10.1016/j.brainresrev.2005.03.006  0.56
2005 Pereira MP, Hurtado O, Cárdenas A, Alonso-Escolano D, Boscá L, Vivancos J, Nombela F, Leza JC, Lorenzo P, Lizasoain I, Moro MA. The nonthiazolidinedione PPARgamma agonist L-796,449 is neuroprotective in experimental stroke. Journal of Neuropathology and Experimental Neurology. 64: 797-805. PMID 16141790  0.56
2005 Fernández-López D, Martínez-Orgado J, Casanova I, Bonet B, Leza JC, Lorenzo P, Moro MA, Lizasoain I. Immature rat brain slices exposed to oxygen-glucose deprivation as an in vitro model of neonatal hypoxic-ischemic encephalopathy. Journal of Neuroscience Methods. 145: 205-12. PMID 15922037 DOI: 10.1016/j.jneumeth.2005.01.005  0.56
2005 García-Bueno B, Madrigal JL, Lizasoain I, Moro MA, Lorenzo P, Leza JC. Peroxisome proliferator-activated receptor gamma activation decreases neuroinflammation in brain after stress in rats. Biological Psychiatry. 57: 885-94. PMID 15820709 DOI: 10.1016/j.biopsych.2005.01.007  0.56
2005 García-Bueno B, Madrigal JL, Lizasoain I, Moro MA, Lorenzo P, Leza JC. The anti-inflammatory prostaglandin 15d-PGJ2 decreases oxidative/nitrosative mediators in brain after acute stress in rats. Psychopharmacology. 180: 513-22. PMID 15719215 DOI: 10.1007/s00213-005-2195-5  0.56
2005 Pérez-Asensio FJ, Hurtado O, Burguete MC, Moro MA, Salom JB, Lizasoain I, Torregrosa G, Leza JC, Alborch E, Castillo J, Knowles RG, Lorenzo P. Inhibition of iNOS activity by 1400W decreases glutamate release and ameliorates stroke outcome after experimental ischemia. Neurobiology of Disease. 18: 375-84. PMID 15686966 DOI: 10.1016/j.nbd.2004.10.018  0.56
2005 Hurtado O, Moro MA, Cárdenas A, Sánchez V, Fernández-Tomé P, Leza JC, Lorenzo P, Secades JJ, Lozano R, Dávalos A, Castillo J, Lizasoain I. Neuroprotection afforded by prior citicoline administration in experimental brain ischemia: effects on glutamate transport. Neurobiology of Disease. 18: 336-45. PMID 15686962 DOI: 10.1016/j.nbd.2004.10.006  0.56
2005 Pradillo JM, Romera C, Hurtado O, Cárdenas A, Moro MA, Leza JC, Dávalos A, Castillo J, Lorenzo P, Lizasoain I. TNFR1 upregulation mediates tolerance after brain ischemic preconditioning. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 193-203. PMID 15647744 DOI: 10.1038/sj.jcbfm.9600019  0.56
2004 Colón AL, Madrigal JL, Menchén LA, Moro MA, Lizasoain I, Lorenzo P, Leza JC. Stress increases susceptibility to oxidative/nitrosative mucosal damage in an experimental model of colitis in rats. Digestive Diseases and Sciences. 49: 1713-21. PMID 15573932 DOI: 10.1023/B:DDAS.0000043391.64073.e4  0.56
2004 Menchén L, Colón AL, Madrigal JL, Beltrán L, Botella S, Lizasoain I, Leza JC, Moro MA, Menchén P, Cos E, Lorenzo P. Activity of inducible and neuronal nitric oxide synthases in colonic mucosa predicts progression of ulcerative colitis. The American Journal of Gastroenterology. 99: 1756-64. PMID 15330915 DOI: 10.1111/j.1572-0241.2004.40065.x  0.56
2004 Munhoz C, Madrigal JL, García-Bueno B, Pradillo JM, Moro MA, Lizasoain I, Lorenzo P, Scavone C, Leza JC. TNF-alpha accounts for short-term persistence of oxidative status in rat brain after two weeks of repeated stress. The European Journal of Neuroscience. 20: 1125-30. PMID 15305883 DOI: 10.1111/j.1460-9568.2004.03560.x  0.56
2004 Moro MA, Cárdenas A, Hurtado O, Leza JC, Lizasoain I. Role of nitric oxide after brain ischaemia. Cell Calcium. 36: 265-75. PMID 15261482 DOI: 10.1016/j.ceca.2004.02.011  0.56
2004 Romera C, Hurtado O, Botella SH, Lizasoain I, Cárdenas A, Fernández-Tomé P, Leza JC, Lorenzo P, Moro MA. In vitro ischemic tolerance involves upregulation of glutamate transport partly mediated by the TACE/ADAM17-tumor necrosis factor-alpha pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1350-7. PMID 14960606 DOI: 10.1523/JNEUROSCI.1596-03.2004  0.56
2004 Madrigal JLM, Caso J, Hurtado O, Lizasoain I, Moro MA, Lorenzo P, Leza JC. Brain oxidative markers in stress: Posible new drug targets against neuroinflammation Current Neuropharmacology. 2: 183-189. DOI: 10.2174/1570159043476846  0.56
2004 Madrigal JLM, García-Bueno B, Cárdenas A, Lizasoain I, Moro MA, Lorenzo P, Leza JC. Oxidative/nitrosative brain damage in stress: Possible target for neuropsychopharmacological drugs Current Medicinal Chemistry - Central Nervous System Agents. 4: 235-242. DOI: 10.2174/1568015043356850  0.56
2003 Madrigal JL, García-Bueno B, Moro MA, Lizasoain I, Lorenzo P, Leza JC. Relationship between cyclooxygenase-2 and nitric oxide synthase-2 in rat cortex after stress. The European Journal of Neuroscience. 18: 1701-5. PMID 14511348 DOI: 10.1046/j.1460-9568.2003.02888.x  0.56
2003 Hurtado O, De Cristóbal J, Sánchez V, Lizasoain I, Cárdenas A, Pereira MP, Colado MI, Leza JC, Lorenzo P, Moro MA. Inhibition of glutamate release by delaying ATP fall accounts for neuroprotective effects of antioxidants in experimental stroke. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 2082-4. PMID 14500556 DOI: 10.1096/fj.02-1086fje  0.56
2003 Moro MA, Hurtado O, Cárdenas A, Romera C, Madrigal JL, Fernández-Tomé P, Leza JC, Lorenzo P, Lizasoain I. Expression and function of tumour necrosis factor-alpha-converting enzyme in the central nervous system. Neuro-Signals. 12: 53-8. PMID 12876399 DOI: 10.1159/000071814  0.56
2003 Madrigal JL, Caso JR, de Cristóbal J, Cárdenas A, Leza JC, Lizasoain I, Lorenzo P, Moro MA. Effect of subacute and chronic immobilisation stress on the outcome of permanent focal cerebral ischaemia in rats. Brain Research. 979: 137-45. PMID 12850580 DOI: 10.1016/S0006-8993(03)02892-0  0.56
2003 Leza JC. [Fibromyalgia: a challenge for neuroscience]. Revista De Neurologia. 36: 1165-75. PMID 12833238  0.56
2003 Madrigal JL, Moro MA, Lizasoain I, Lorenzo P, Fernández AP, Rodrigo J, Boscá L, Leza JC. Induction of cyclooxygenase-2 accounts for restraint stress-induced oxidative status in rat brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1579-88. PMID 12784118 DOI: 10.1038/sj.npp.1300187  0.56
2003 Fernández AP, Alonso D, Lisazoaín I, Serrano J, Leza JC, Bentura ML, López JC, Manuel Encinas J, Fernández-Vizarra P, Castro-Blanco S, Martínez A, Martinez-Murillo R, Lorenzo P, Pedrosa JA, Peinado MA, et al. Postnatal changes in the nitric oxide system of the rat cerebral cortex after hypoxia during delivery. Brain Research. Developmental Brain Research. 142: 177-92. PMID 12711369 DOI: 10.1016/S0165-3806(03)00068-3  0.56
2002 Cárdenas A, Moro MA, Leza JC, O'Shea E, Dávalos A, Castillo J, Lorenzo P, Lizasoain I. Upregulation of TACE/ADAM17 after ischemic preconditioning is involved in brain tolerance. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 1297-302. PMID 12439286 DOI: 10.1097/00004647-200211000-00002  0.56
2002 Molina JA, Leza JC, Ortiz S, Moro MA, Pérez S, Lizasoaín I, Urigüen L, Oliva JM, Manzanares J. Cerebrospinal fluid and plasma concentrations of nitric oxide metabolites are increased in dementia with Lewy bodies. Neuroscience Letters. 333: 151-3. PMID 12419502 DOI: 10.1016/S0304-3940(02)01026-1  0.56
2002 Madrigal JL, Moro MA, Lizasoain I, Lorenzo P, Leza JC. Stress-induced increase in extracellular sucrose space in rats is mediated by nitric oxide. Brain Research. 938: 87-91. PMID 12031539 DOI: 10.1016/S0006-8993(02)02467-8  0.56
2002 Hurtado O, Lizasoain I, Fernández-Tomé P, Alvarez-Barrientos A, Leza JC, Lorenzo P, Moro MA. TACE/ADAM17-TNF-alpha pathway in rat cortical cultures after exposure to oxygen-glucose deprivation or glutamate. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 576-85. PMID 11973430 DOI: 10.1097/00004647-200205000-00009  0.56
2002 De Cristóbal J, Madrigal JL, Lizasoain I, Lorenzo P, Leza JC, Moro MA. Aspirin inhibits stress-induced increase in plasma glutamate, brain oxidative damage and ATP fall in rats. Neuroreport. 13: 217-21. PMID 11893913  0.56
2002 Madrigal JL, Hurtado O, Moro MA, Lizasoain I, Lorenzo P, Castrillo A, Boscá L, Leza JC. The increase in TNF-alpha levels is implicated in NF-kappaB activation and inducible nitric oxide synthase expression in brain cortex after immobilization stress. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 26: 155-63. PMID 11790511 DOI: 10.1016/S0893-133X(01)00292-5  0.56
2002 De Cristóbal J, Cárdenas A, Lizasoain I, Leza JC, Fernández-Tomé P, Lorenzo P, Moro MA. Inhibition of glutamate release via recovery of ATP levels accounts for a neuroprotective effect of aspirin in rat cortical neurons exposed to oxygen-glucose deprivation. Stroke; a Journal of Cerebral Circulation. 33: 261-7. PMID 11779920 DOI: 10.1161/hs0102.101299  0.56
2001 Colón AL, Menchén LA, Hurtado O, De Cristóbal J, Lizasoain I, Leza JC, Lorenzo P, Moro MA. Implication of TNF-alpha convertase (TACE/ADAM17) in inducible nitric oxide synthase expression and inflammation in an experimental model of colitis. Cytokine. 16: 220-6. PMID 11884025 DOI: 10.1006/cyto.2001.0969  0.56
2001 De Cristóbal J, Moro MA, Dávalos A, Castillo J, Leza JC, Camarero J, Colado MI, Lorenzo P, Lizasoain I. Neuroprotective effect of aspirin by inhibition of glutamate release after permanent focal cerebral ischaemia in rats. Journal of Neurochemistry. 79: 456-9. PMID 11677274 DOI: 10.1046/j.1471-4159.2001.00600.x  0.56
2001 Menchén LA, Colón AL, Moro MA, Leza JC, Lizasoain I, Menchén P, Alvarez E, Lorenzo P. N-(3-(aminomethyl)benzyl)acetamidine, an inducible nitric oxide synthase inhibitor, decreases colonic inflammation induced by trinitrobenzene sulphonic acid in rats. Life Sciences. 69: 479-91. PMID 11459438 DOI: 10.1016/S0024-3205(01)01139-0  0.56
2001 Hurtado O, Cárdenas A, Lizasoain I, Boscá L, Leza JC, Lorenzo P, Moro MA. Up-regulation of TNF-alpha convertase (TACE/ADAM17) after oxygen-glucose deprivation in rat forebrain slices. Neuropharmacology. 40: 1094-102. PMID 11406201 DOI: 10.1016/S0028-3908(01)00035-1  0.56
2001 Madrigal JL, Moro MA, Lizasoain I, Lorenzo P, Castrillo A, Boscá L, Leza JC. Inducible nitric oxide synthase expression in brain cortex after acute restraint stress is regulated by nuclear factor kappaB-mediated mechanisms. Journal of Neurochemistry. 76: 532-8. PMID 11208916 DOI: 10.1046/j.1471-4159.2001.00108.x  0.56
2001 Madrigal JL, Olivenza R, Moro MA, Lizasoain I, Lorenzo P, Rodrigo J, Leza JC. Glutathione depletion, lipid peroxidation and mitochondrial dysfunction are induced by chronic stress in rat brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 420-9. PMID 11182537 DOI: 10.1016/S0893-133X(00)00208-6  0.56
2000 Cárdenas A, Hurtado O, Leza JC, Lorenzo P, Bartrons R, Lizasoain I, Moro MA. Fructose-1,6-bisphosphate inhibits the expression of inducible nitric oxide synthase caused by oxygen-glucose deprivation through the inhibition of glutamate release in rat forebrain slices. Naunyn-Schmiedeberg's Archives of Pharmacology. 362: 208-12. PMID 10997722 DOI: 10.1007/s002100000286  0.56
2000 Colón AL, Menchén L, Lizasoain I, Leza JC, Menchén P, González-Lara V, Moro MA, Lorenzo P. Inducible nitric oxide synthase activity is expressed not only in inflamed but also in normal colonic mucosa in patients with ulcerative colitis: a potential prognostic marker. The American Journal of Gastroenterology. 95: 1371-3. PMID 10811365 DOI: 10.1111/j.1572-0241.2000.02047.x  0.56
2000 Cárdenas A, Moro MA, Hurtado O, Leza JC, Lorenzo P, Castrillo A, Bodelón OG, Boscá L, Lizasoain I. Implication of glutamate in the expression of inducible nitric oxide synthase after oxygen and glucose deprivation in rat forebrain slices. Journal of Neurochemistry. 74: 2041-8. PMID 10800947 DOI: 10.1046/j.1471-4159.2000.0742041.x  0.56
2000 Moro MA, De Alba J, Cárdenas A, De Cristóbal J, Leza JC, Lizasoain I, Díaz-Guerra MJ, Boscá L, Lorenzo P. Mechanisms of the neuroprotective effect of aspirin after oxygen and glucose deprivation in rat forebrain slices. Neuropharmacology. 39: 1309-18. PMID 10760373 DOI: 10.1016/S0028-3908(99)00226-9  0.56
2000 Cuéllar B, Fernández AP, Lizasoain I, Moro MA, Lorenzo P, Bentura ML, Rodrigo J, Leza JC. Up-regulation of neuronal NO synthase immunoreactivity in opiate dependence and withdrawal. Psychopharmacology. 148: 66-73. PMID 10663419  0.56
2000 Olivenza R, Moro MA, Lizasoain I, Lorenzo P, Fernández AP, Rodrigo J, Boscá L, Leza JC. Chronic stress induces the expression of inducible nitric oxide synthase in rat brain cortex. Journal of Neurochemistry. 74: 785-91. PMID 10646531 DOI: 10.1046/j.1471-4159.2000.740785.x  0.56
2000 Leza JC, Lorenzo P. Pharmacological effects of cannabinoids | Efectos farmacologicos de los cannabinoides Adicciones. 12: 109-116.  0.56
2000 Lorenzo P, Leza JC. Therapeutic uses of cannabis | Utilidad terapeutica del cannabis y derivados Adicciones. 12: 149-168.  0.56
1999 Fernández-Tomé P, Lizasoain I, Leza JC, Lorenzo P, Moro MA. Neuroprotective effects of DETA-NONOate, a nitric oxide donor, on hydrogen peroxide-induced neurotoxicity in cortical neurones. Neuropharmacology. 38: 1307-15. PMID 10471084 DOI: 10.1016/S0028-3908(99)00069-6  0.56
1999 De Alba J, Cárdenas A, Moro MA, Leza JC, Lorenzo P, Lizasoain I. Use of brain slices in the study of pathogenic role of inducible nitric oxide synthase in cerebral ischemia-reperfusion. General Pharmacology. 32: 577-81. PMID 10382860 DOI: 10.1016/S0306-3623(98)00280-8  0.56
1999 Gavilanes J, Moro MA, Lizasoain I, Lorenzo P, Pérez A, Leza JC, Alvarez-Vicent JJ. Nitric oxide synthase activity in human squamous cell carcinoma of the head and neck. The Laryngoscope. 109: 148-52. PMID 9917057 DOI: 10.1097/00005537-199901000-00028  0.56
1999 De Alba J, Cárdenas A, Moro MA, Leza JC, Lorenzo P, Boscá L, Lizasoain I. Down-regulation of neuronal nitric oxide synthase by nitric oxide after oxygen-glucose deprivation in rat forebrain slices. Journal of Neurochemistry. 72: 248-54. PMID 9886076 DOI: 10.1046/j.1471-4159.1999.0720248.x  0.56
1998 Moro MA, Fernández-Tomé P, Leza JC, Lorenzo P, Lizasoain I. Neuronal death induced by SIN-1 in the presence of superoxide dismutase: protection by cyclic GMP. Neuropharmacology. 37: 1071-9. PMID 9833636 DOI: 10.1016/S0028-3908(98)00104-X  0.56
1998 Uttenthal LO, Alonso D, Fernández AP, Campbell RO, Moro MA, Leza JC, Lizasoain I, Esteban FJ, Barroso JB, Valderrama R, Pedrosa JA, Peinado MA, Serrano J, Richart A, Bentura ML, et al. Neuronal and inducible nitric oxide synthase and nitrotyrosine immunoreactivities in the cerebral cortex of the aging rat. Microscopy Research and Technique. 43: 75-88. PMID 9829462 DOI: 10.1002/(SICI)1097-0029(19981001)43:1<75::AID-JEMT11>3.0.CO;2-0  0.56
1998 Cárdenas A, De Alba J, Moro MA, Leza JC, Lorenzo P, Lizasoain I. Protective effect of N-(3-(aminomethyl)benzyl) acetamidine, an inducible nitric oxide synthase inhibitor, in brain slices exposed to oxygen-glucose deprivation. European Journal of Pharmacology. 354: 161-5. PMID 9754916 DOI: 10.1016/S0014-2999(98)00458-0  0.56
1998 Moro MA, De Alba J, Leza JC, Lorenzo P, Fernández AP, Bentura ML, Boscá L, Rodrigo J, Lizasoain I. Neuronal expression of inducible nitric oxide synthase after oxygen and glucose deprivation in rat forebrain slices. The European Journal of Neuroscience. 10: 445-56. PMID 9749707 DOI: 10.1046/j.1460-9568.1998.00028.x  0.56
1998 Leza JC, Salas E, Sawicki G, Russell JC, Radomski MW. The effects of stress on homeostasis in JCR-LA-cp rats: the role of nitric oxide. The Journal of Pharmacology and Experimental Therapeutics. 286: 1397-403. PMID 9732403  0.56
1998 Moro MA, Leza JC, Lorenzo P, Lizasoain I. Peroxynitrite causes aspartate release from dissociated rat cerebellar granule neurones. Free Radical Research. 28: 193-204. PMID 9645395  0.56
1996 Lizasoain I, Leza JC, Cuéllar B, Moro MA, Lorenzo P. Inhibition of morphine withdrawal by lamotrigine: involvement of nitric oxide. European Journal of Pharmacology. 299: 41-5. PMID 8901006 DOI: 10.1016/0014-2999(95)00851-9  0.56
1996 San-Martin-Clark O, Cuellar B, Leza JC, Lizasoain I, Lorenzo P. Effects of trepelennamine on brain monoamine turnover in morphine dependent and abstinent mice. Psychopharmacology. 123: 297-302. PMID 8833423  0.56
1996 Leza JC, Lizasoain I, Cuéllar B, Moro MA, Lorenzo P. Correlation between brain nitric oxide synthase activity and opiate withdrawal. Naunyn-Schmiedeberg's Archives of Pharmacology. 353: 349-54. PMID 8692292 DOI: 10.1007/BF00168639  0.56
1995 Leza JC, Lizasoain I, San-Martín-Clark O, Lorenzo P. Morphine-induced changes in cerebral and cerebellar nitric oxide synthase activity. European Journal of Pharmacology. 285: 95-8. PMID 8846816 DOI: 10.1016/0014-2999(95)00474-Y  0.56
1995 Portolés JM, Ojeda G, Ronda M, Leza JC, Rojo JM. Suppression of immune parameters in animal models of morphine dependence. Immunological Investigations. 24: 643-52. PMID 7622200 DOI: 10.3109/08820139509066864  0.56
1995 San-Martín-Clark O, Cuéllar B, De Alba J, Leza JC, Lorenzo P. Changes induced by sodium cromoglycate in brain catecholamine turnover in morphine dependent and abstinent mice. Psychopharmacology. 118: 347-53. PMID 7617828 DOI: 10.1007/BF02245965  0.56
1995 Villamor E, Pérez-Vizcaíno F, Ruiz T, Leza JC, Moro M, Tamargo J. Group B Streptococcus and E. coli LPS-induced NO-dependent hyporesponsiveness to noradrenaline in isolated intrapulmonary arteries of neonatal piglets. British Journal of Pharmacology. 115: 261-6. PMID 7545518  0.56
1993 Leza JC, Lorenzo P. [The central effects of antihistaminic drugs]. Medicina ClíNica. 101: 24-7. PMID 8100286  0.56
1993 San-Martin-Clark O, Leza JC, Lizasoain I, Lorenzo P. Changes induced by sodium cromoglycate on brain serotonin turnover in morphine dependent and abstinent mice. Psychopharmacology. 111: 233-8. PMID 7532863 DOI: 10.1007/BF02245529  0.56
1992 Leza JC, Lizasoain I, Martín-Clark OS, Lorenzo P. Role of sodium cromoglycate on analgesia, locomotor activity and opiate withdrawal in mice. Psychopharmacology. 107: 595-600. PMID 1376478 DOI: 10.1007/BF02245276  0.56
1991 Lizasoain I, Leza JC, Lorenzo P. Buprenorphine: bell-shaped dose-response curve for its antagonist effects. General Pharmacology. 22: 297-300. PMID 2055424 DOI: 10.1016/0306-3623(91)90452-C  0.56
1991 Navarro M, Leza JC, Lizasoain I, Lorenzo P. Influence of psychogenetics in opiate tolerance and abstinence in mice. General Pharmacology. 22: 713-6. PMID 1936907 DOI: 10.1016/0306-3623(91)90084-J  0.56
1991 Navarro M, Lizasoain I, Leza JC, Lorenzo P. An original method for assessment of the jumping test. Methods and Findings in Experimental and Clinical Pharmacology. 13: 443-7. PMID 1784140  0.56
1991 Leza JC, Lizasoain I, Lorenzo P. Effects of antihistaminics on locomotor activity in mice. Comparison with opiate and amphetamine-induced hyperactivity. General Pharmacology. 22: 293-6. PMID 1676005 DOI: 10.1016/0306-3623(91)90451-B  0.56
1990 Martin MI, Lizasoain I, Leza JC. Calcium channel blockers: effect on morphine-induced hypermotility. Psychopharmacology. 101: 267-70. PMID 2349368 DOI: 10.1007/BF02244138  0.56
1990 Leza JC, Lizasoain I, Lorenzo P. H1- and H2-histamine receptor blockers and opiate analgesia in mice. Methods and Findings in Experimental and Clinical Pharmacology. 12: 671-8. PMID 1983158  0.56
1990 Leza JC, Lizasoain I, Lorenzo P. Effects of antihistaminics on naloxone-induced withdrawal in morphine-dependent mice. Psychopharmacology. 102: 106-11. PMID 1975446 DOI: 10.1007/BF02245753  0.56
1988 Lorenzo P, Leza JC. [Buprenorphine: pharmacologic and clinical aspects]. Revista ClíNica EspañOla. 182: 230-3. PMID 2901137  0.56
1988 Leza JC, Lizasoain I, Martin MI, Lorenzo P. Effects of nifedipine, verapamil and diltiazem on naloxone-induced abstinence in morphine-dependent mice Revista De Farmacologia Clinica Y Experimental. 5: 383-387.  0.56
1987 Leza JC, Lizasoain I, Beneit JV, Lorenzo P. Buprenorphine suppresses weight loss and abstinence in morphine-dependent mice Revista De Farmacologia Clinica Y Experimental. 4: 377-383.  0.56
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