| Year |
Citation |
Score |
| 1973 |
Roughton FJ, Severinghaus JW. Accurate determination of O2 dissociation curve of human blood above 98.7 percent saturation with data on O2 solubility in unmodified human blood from 0 degrees to 37 degrees C. Journal of Applied Physiology. 35: 861-9. PMID 4765824 |
0.298 |
|
| 1972 |
Brenna O, Luzzana M, Pace M, Perrella M, Rossi F, Rossi-Bernardi L, Roughton FJ. The interaction between hemoglobin and its "oxygen-linked" ligands. Advances in Experimental Medicine and Biology. 28: 19-40. PMID 5085168 |
0.311 |
|
| 1972 |
Luzzana M, Marre C, Perrella M, Rossi-Bernardi L, Roughton FJ. The carbamate equilibria of CO 2 with human haemoglobin under physiological conditions. The Journal of Physiology. 224: 65P-66P. PMID 5071413 |
0.229 |
|
| 1972 |
Dahms T, Horvath SM, Luzzana M, Rossi-Bernardi L, Roughton FJ, Stella G. The regulation of oxygen affinity of human haemoglobin. The Journal of Physiology. 223: 29P-31P. PMID 5046159 |
0.333 |
|
| 1971 |
Helen RS, Roughton FJ, Fatt I. Polarographic studies of oxygen-hemoglobin equilibria at very low saturations. Journal of Applied Physiology. 30: 575-9. PMID 5572776 |
0.36 |
|
| 1970 |
Pace M, Rossi-Bernardi L, Roughton FJ. The effect of organic phosphates on the reactions of haemoglobin and oxyhaemoglobin (carboxyhaemoglobin) with carbon dioxide. The Biochemical Journal. 119: 67P-68P. PMID 5531180 |
0.374 |
|
| 1970 |
Rossi-Bernardi L, Roughton FJ. The role of oxygen-linked carbamate in the transport of CO2 by human erythrocytes under physiological conditions. The Journal of Physiology. 209: Suppl:25P+. PMID 5499061 |
0.326 |
|
| 1970 |
Roughton FJ. Some recent work on the interactions of oxygen, carbon dioxide and haemoglobin. The Biochemical Journal. 117: 801-12. PMID 5451906 |
0.382 |
|
| 1970 |
Roughton FJ. The equilibrium of carbon monoxide with human hemoglobin in whole blood. Annals of the New York Academy of Sciences. 174: 177-88. PMID 5289595 |
0.368 |
|
| 1970 |
Hemingway A, Hemingway CJ, Roughton FJ. The rate of the chloride shift of respiration studied with a rapid filtration method. Respiration Physiology. 10: 1-9. PMID 4988892 DOI: 10.1016/0034-5687(70)90021-6 |
0.243 |
|
| 1968 |
Kernohan JC, Roughton FJ. Thermal studies of the rates of the reactions of carbon dioxide in concentrated haemoglobin solutions and in red blood cells. A. The reactions catalysed by carbonic anhydrase. B. The carbamino reactions of oxygenated and deoxygenated haemoglobin. The Journal of Physiology. 197: 345-61. PMID 4975618 |
0.447 |
|
| 1967 |
Rossi-Bernardi L, Roughton FJ. The specific influence of carbon dioxide and carbamate compounds on the buffer power and Bohr effects in human haemoglobin solutions. The Journal of Physiology. 189: 1-29. PMID 16992238 |
0.34 |
|
| 1967 |
Rossi-Bernardi L, Roughton FJ. The effect of temperature on the oxygen-linked ionizations of hemoglobin. The Journal of Biological Chemistry. 242: 784-92. PMID 6020434 |
0.326 |
|
| 1967 |
Chipperfield JR, Rossi-Bernardi L, Roughton FJ. Direct calorimetric studies on the heats of ionization of oxygenated and deoxygenated hemoglobin. The Journal of Biological Chemistry. 242: 777-83. PMID 6020433 |
0.347 |
|
| 1966 |
Roughton FJ, Rossi-Bernardi L. The carbamate reaction of carbon dioxide with glycyl-glycine. Proceedings of the Royal Society of London. Series B, Biological Sciences. 164: 381-400. PMID 4379575 DOI: 10.1098/Rspb.1966.0039 |
0.458 |
|
| 1965 |
Roughton FJ. The oxygen equilibrium of mammalian hemoglobin. Some old and new physicochemical studies. The Journal of General Physiology. 49: Suppl:105-26. PMID 5859923 |
0.374 |
|
| 1965 |
Gibson QH, Roughton FJ. Further studies on the kinetics and equilibria of the reaction of nitric oxide with haemoproteins. Proceedings of the Royal Society of London. Series B, Biological Sciences. 163: 197-205. PMID 4378479 DOI: 10.1098/Rspb.1965.0066 |
0.39 |
|
| 1964 |
Rossi L, Roughton FJ. [Equilibria and kinetics of the reactions of CO2 in biological systems: carbaminic equilibrium between CO2 in biological systems: carbaminic equilibrium between CO2 and glycylglycine]. Bollettino Della Societã Italiana Di Biologia Sperimentale. 40: Suppl:2221-5. PMID 5888664 |
0.286 |
|
| 1964 |
De Land E, Rossi L, Roughton FJ. [The determination, with a statistical method, of the constants of dissociation of "oxygen-sensitive" groups in hemoglobin]. Bollettino Della Societã Italiana Di Biologia Sperimentale. 40: Suppl:2219-21. PMID 5876736 |
0.34 |
|
| 1963 |
CHIAPPERFIELD JR, ROSSI L, ROUGHTON FJ. [THERMODYNAMICS OF THE BOHR EFFECT IN HUMAN HEMOGLOBIN. I. THE EFFECT OF TEMPERATURE AND PH ON THE NUMBER OF DISSOCIATED HYDROGEN IONS AFTER OXYGENATION]. Bollettino Della Societã Italiana Di Biologia Sperimentale. 39: 1995-8. PMID 14153884 |
0.294 |
|
| 1963 |
ROUGHTON FJ. THE ACCURATE GASOMETRIC DETERMINATION OF THE OXYGEN-HEMOGLOBIN EQUILIBRIUM IN DILUTE SOLUTIONS OF SHEEP HEMOGLOBIN. Clinical Chemistry. 12: 682-709. PMID 14099730 |
0.378 |
|
| 1963 |
KERNOHAN JC, FORREST WW, ROUGHTON FJ. The activity of concentrated solutions of carbonic anhydrase. Biochimica Et Biophysica Acta. 67: 31-41. PMID 14032069 |
0.323 |
|
| 1963 |
SIRS JA, ROUGHTON FJ. Stopped-flow measurements of CO and O2 uptake by hemoglobin in sheep erythrocytes. Journal of Applied Physiology. 18: 158-65. PMID 13977750 |
0.269 |
|
| 1963 |
ROUGHTON FJ. Kinetics of gas transport in the blood. British Medical Bulletin. 19: 80-9. PMID 13975442 |
0.254 |
|
| 1960 |
AINSWORTH S, GIBSON QH, ROUGHTON FJ. The kinetics of sheep haemoglobin with isocyanides. Proceedings of the Royal Society of London. Series B, Biological Sciences. 152: 331-45. PMID 13848748 DOI: 10.1098/rspb.1960.0042 |
0.371 |
|
| 1959 |
HALPERIN MH, McFARLAND RA, NIVEN JI, ROUGHTON FJ. The time course of the effects of carbon monoxide on visual thresholds. The Journal of Physiology. 146: 583-93. PMID 13665680 |
0.279 |
|
| 1959 |
Roughton F. Diffusion and Simultaneous Chemical Reaction Velocity in Haemoglobin Solutions and Red Cell Suspensions Progress in Biophysics and Biophysical Chemistry. 9: 55-104. DOI: 10.1016/S0096-4174(18)30166-5 |
0.337 |
|
| 1958 |
ROUGHTON FJ, RUPP JC. Problems concerning the kinetics of the reactions of oxygen, carbon monoxide and carbon dioxide in the intact red cell. Annals of the New York Academy of Sciences. 75: 156-66. PMID 13627813 |
0.425 |
|
| 1958 |
GIBSON QH, ROUGHTON FJ. The velocity of combination of the first oxygen molecule with sheep haemoglobin. The Journal of Physiology. 140: 37-8P. PMID 13514695 |
0.321 |
|
| 1957 |
ROUGHTON FJ, FORSTER RE. Relative importance of diffusion and chemical reaction rates in determining rate of exchange of gases in the human lung, with special reference to true diffusing capacity of pulmonary membrane and volume of blood in the lung capillaries. Journal of Applied Physiology. 11: 290-302. PMID 13475180 |
0.3 |
|
| 1957 |
FORSTER RE, ROUGHTON FJ, CANDER L, BRISCOE WA, KREUZER F. Apparent pulmonary diffusing capacity for CO at varying alveolar O2 tensions. Journal of Applied Physiology. 11: 277-89. PMID 13475179 |
0.261 |
|
| 1957 |
ROUGHTON FJ, FORSTER RE, CANDER L. Rate at which carbon monoxide replaces oxygen from combination with human hemoglobin in solution and in the red cell. Journal of Applied Physiology. 11: 269-76. PMID 13475178 |
0.411 |
|
| 1957 |
FORSTER RE, ROUGHTON FJ, KREUZER F, BRISCOE WA. Photocolorimetric determination of rate of uptake of CO and O2 by reduced human red cell suspensions at 37 degrees C. Journal of Applied Physiology. 11: 260-8. PMID 13475177 DOI: 10.1152/JAPPL.1957.11.2.260 |
0.271 |
|
| 1957 |
GIBSON QH, ROUGHTON FJ. The kinetics of dissociation of the first ligand molecule from fully saturated carboxyhaemoglobin and nitric oxide haemoglobin in sheep blood solutions. Proceedings of the Royal Society of London. Series B, Biological Sciences. 147: 44-56. PMID 13465712 DOI: 10.1098/rspb.1957.0035 |
0.444 |
|
| 1957 |
GIBSON WH, ROUGHTON FJ. The kinetics and equilibria of the reactions of nitric oxide with sheep haemoglobin. The Journal of Physiology. 136: 507-24. PMID 13429517 DOI: 10.1113/jphysiol.1957.sp005777 |
0.3 |
|
| 1956 |
GIBSON QH, ROUGHTON FJ. The determination of the velocity constants of the four successive reactions of carbon monoxide with sheep haemoglobin. Proceedings of the Royal Society of London. Series B, Biological Sciences. 146: 206-24. PMID 13420144 DOI: 10.1098/rspb.1957.0005 |
0.431 |
|
| 1956 |
KLUG A, KREUZER F, ROUGHTON FJ. Simultaneous diffusion and chemical reaction in thin layers of haemoglobin solution. Proceedings of the Royal Society of London. Series B, Biological Sciences. 145: 452-72. PMID 13359398 DOI: 10.1098/Rspb.1956.0056 |
0.463 |
|
| 1956 |
KLUG A, KREUZER F, ROUGHTON FJ. The diffusion of oxygen in concentrated haemoglobin solutions. Helvetica Physiologica Et Pharmacologica Acta. 14: 212-8. PMID 13345213 |
0.344 |
|
| 1955 |
GIBSON QH, ROUGHTON FJ. The kinetics of dissociation of the first oxygen molecule from fully saturated oxyhaemoglobin in sheep blood solutions. Proceedings of the Royal Society of London. Series B, Biological Sciences. 143: 310-34. PMID 14371610 DOI: 10.1098/rspb.1955.0014 |
0.462 |
|
| 1955 |
OTIS AB, ROUGHTON FJ. Improved gasometric methods for estimating oxygen content and percentage saturation in haemoglobin dissociation curve determinations. Proceedings of the Royal Society of London. Series B, Biological Sciences. 144: 55-67. PMID 13254714 DOI: 10.1098/Rspb.1955.0033 |
0.501 |
|
| 1955 |
ROUGHTON FJ, OTIS AB, LYSTER RL. The determination of the individual equilibrium constants of the four intermediate reactions between oxygen and sheep haemoglobin. Proceedings of the Royal Society of London. Series B, Biological Sciences. 144: 29-54. PMID 13254713 DOI: 10.1098/Rspb.1955.0032 |
0.412 |
|
| 1955 |
GIBSON QH, KREUZER F, MEDA E, ROUGHTON FJ. The kinetics of human haemoglobin in solution and in the red cell at 37 degrees C. The Journal of Physiology. 129: 65-89. PMID 13252585 DOI: 10.1113/jphysiol.1955.sp005339 |
0.274 |
|
| 1955 |
GIBSON QH, ROUGHTON FJ. The reactions of sheep haemoglobin with nitric acid oxide. The Journal of Physiology. 128: 69-70P. PMID 13243362 |
0.273 |
|
| 1954 |
ROUGHTON FJ. The equilibrium between carbon monoxide and sheep haemoglobin at very high percentage saturations. The Journal of Physiology. 126: 359-83. PMID 13222290 |
0.345 |
|
| 1953 |
GIBSON QH, MEDA E, ROUGHTON FJ. [Studies on the kinetics of the reaction of human hemoglobin with carbon monoxide. II..]. Bollettino Della Societã Italiana Di Biologia Sperimentale. 29: 1472-3. PMID 13140575 |
0.383 |
|
| 1953 |
GIBSON QH, MEDA E, ROUGHTON FJ. [Studies on the kinetics of the reaction of human hemoglobin with oxygen. I..]. Bollettino Della Societã Italiana Di Biologia Sperimentale. 29: 1471-2. PMID 13140574 |
0.418 |
|
| 1953 |
GIBSON QH, ROUGHTON FJ. The effects of temperature and of p-chloromercuribenzoic acid on the reaction Hb4O8<==>Hb4 O6 + O2 in solutions of sheep blood. The Journal of Physiology. 122: 45-6P. PMID 13109802 |
0.323 |
|
| 1952 |
CHANCE B, GREENSTEIN DS, ROUGHTON FJ. The mechanism of catalase action. I. Steady-state analysis. Archives of Biochemistry and Biophysics. 37: 301-21. PMID 14953443 |
0.333 |
|
| 1952 |
ROUGHTON FJ. Diffusion and chemical reaction velocity in cylindrical and spherical systems of physiological interest. Proceedings of the Royal Society of London. Series B, Biological Sciences. 140: 203-29. PMID 13003927 DOI: 10.1098/Rspb.1952.0059 |
0.461 |
|
| 1952 |
LONGMUIR IS, ROUGHTON FJ. The diffusion coefficients of carbon monoxide and nitrogen in haemoglobin solutions. The Journal of Physiology. 118: 264-75. PMID 13000709 |
0.344 |
|
| 1952 |
GIBSON QH, ROUGHTON FJ. The velocity constants of the reaction Hb4X3X=Hb4X4(X=O2 or CO) for mammalian haemoglobin. The Journal of Physiology. 117: 76P-77P. PMID 12991267 |
0.312 |
|
| 1951 |
OTIS AB, ROUGHTON FJ. The determination of the equilibrium constants of the four intermediate reactions of oxygen with haemoglobin. The Journal of Physiology. 115: 16p. PMID 14889447 |
0.43 |
|
| 1951 |
OTIS AB, ROUGHTON FJ. Simultaneous determination of oxygen content and gas-combining capacity of blood or haemoglobin solutions by gasometric technique. The Journal of Physiology. 115: 3p-4p. PMID 14889436 |
0.337 |
|
| 1951 |
NICOLSON P, ROUGHTON FJ. A theoretical study of the influence of diffusion and chemical reaction velocity on the rate of exchange of carbon monoxide and oxygen between the red blood corpuscle and the surrounding fluid. Proceedings of the Royal Society of London. Series B, Biological Sciences. 138: 241-64. PMID 14853968 DOI: 10.1098/Rspb.1951.0020 |
0.481 |
|
| 1951 |
PAUL W, ROUGHTON FJ. The equilibrium between oxygen and sheep haemoglobin at very low percentage saturations. The Journal of Physiology. 113: 23-35. PMID 14825232 |
0.362 |
|
| 1950 |
LEGGE JW, ROUGHTON FJ. Some observations on the kinetics of haemoglobin in solution and in the haemoglobin in solution and in the red blood corpuscle. The Biochemical Journal. 47: 43-52. PMID 14791303 DOI: 10.1042/BJ0470043 |
0.296 |
|
| 1949 |
ROUGHTON FJ. The carbamino combination of CO2 with reduced haemoglobin and oxyhaemoglobin. The Biochemical Journal. 44: xxx. PMID 18229370 |
0.244 |
|
| 1949 |
PAUL W, ROUGHTON FJ. The bottom of the oxyhaemoglobin dissociation curve of diluted sheep blood. The Journal of Physiology. 109: Proc, 29. PMID 15395055 |
0.271 |
|
| 1949 |
ROUGHTON FJ. The role of carbamino compounds of haemoglobin in the respiratory transport of CO2 by the blood. The Journal of Physiology. 109: Proc, 12. PMID 15395035 |
0.259 |
|
| 1948 |
DAVIES RE, ROUGHTON FJ. Hydrochloric acid production by isolated gastric mucosa. The Biochemical Journal. 42: 609-21. PMID 18876944 |
0.179 |
|
| 1948 |
Krebs HA, Roughton FJ. Carbonic anhydrase as a tool in studying the mechanism of reactions involving H(2)CO(3), CO(2) or HCO(3)'. The Biochemical Journal. 43: 550-5. PMID 16748449 DOI: 10.1042/Bj0430550 |
0.547 |
|
| 1946 |
ROOT WS, ROUGHTON FJ, GREGERSEN MI. Simultaneous determinations of blood volume by CO and dye (T-1824) under various conditions. The American Journal of Physiology. 146: 739-55. PMID 20996497 |
0.275 |
|
| 1946 |
Roughton FJ, Booth VH. The effect of substrate concentration, pH and other factors upon the activity of carbonic anhydrase. The Biochemical Journal. 40: 319-30. PMID 16748007 |
0.293 |
|
| 1946 |
Roughton FJ, Booth VH. The manometric determination of the activity of carbonic anhydrase under varied conditions. The Biochemical Journal. 40: 309-19. PMID 16748006 |
0.312 |
|
| 1945 |
ROUGHTON FJ, ROOT WS. The fate of CO in the body during recovery from mild carbon monoxide poisoning in man. The American Journal of Physiology. 145: 239-52. PMID 21009265 |
0.308 |
|
| 1945 |
Roughton F, Root W. THE ESTIMATION OF SMALL AMOUNTS OF CARBON MONOXIDE IN AIR Journal of Biological Chemistry. 160: 135-148. DOI: 10.1016/s0021-9258(18)43105-5 |
0.316 |
|
| 1945 |
Roughton F, Root W. THE ESTIMATION OF SMALL AMOUNTS OF CARBON MONOXIDE IN BLOOD Journal of Biological Chemistry. 160: 123-133. DOI: 10.1016/s0021-9258(18)43104-3 |
0.345 |
|
| 1943 |
Roughton F, Scholander P. MICRO GASOMETRIC ESTIMATION OF THE BLOOD GASES Journal of Biological Chemistry. 148: 541-550. DOI: 10.1016/S0021-9258(18)72253-9 |
0.252 |
|
| 1942 |
Horvath S, Roughton F. IMPROVEMENTS IN THE GASOMETRIC ESTIMATION OF CARBON MONOXIDE IN BLOOD Journal of Biological Chemistry. 144: 747-755. DOI: 10.1016/s0021-9258(18)72500-3 |
0.34 |
|
| 1941 |
Roughton F. A SIMPLE, ACCURATE METHOD OF ESTIMATING CARBON MONOXIDE IN BLOOD Journal of Biological Chemistry. 137: 617-625. DOI: 10.1016/s0021-9258(19)56167-1 |
0.344 |
|
| 1941 |
Roughton F. A METHOD OF ALLOWING FOR THE INFLUENCE OF DIFFUSION IN MANOMETRIC MEASUREMENTS OF CERTAIN RAPID BIOCHEMICAL REACTIONS Journal of Biological Chemistry. 141: 129-145. DOI: 10.1016/s0021-9258(18)72828-7 |
0.336 |
|
| 1938 |
Roughton FJ, Booth VH. The catalytic effect of buffers on the reaction CO(2)+H(2)Oright harpoon over left harpoonH(2)CO(3). The Biochemical Journal. 32: 2049-69. PMID 16746846 DOI: 10.1042/BJ0322049 |
0.278 |
|
| 1936 |
Roughton FJ, Adair GS, Barcroft J, Goldschmidt G, Herkel W, Hill RM, Keys AB, Ray GB. The thermochemistry of the oxygen-haemoglobin reaction: Comparison of the heat as measured directly on purified haemoglobin with that calculated indirectly by the Van't Hoff Isochore. The Biochemical Journal. 30: 2117-33. PMID 16746269 DOI: 10.1042/BJ0302117 |
0.69 |
|
| 1935 |
Bateman JB, Roughton FJ. The time course of the heat effects in rapid chemical changes: Improved apparatus and methods. II. The reactions of haemoglobin with oxygen and carbon monoxide. The Biochemical Journal. 29: 2622-38. PMID 16745946 |
0.416 |
|
| 1935 |
Roughton FJ. Thermochemistry of the oxygen-haemoglobin reaction: Direct measurements of the heat of reaction under various conditions. The Biochemical Journal. 29: 2604-21. PMID 16745945 |
0.404 |
|
| 1934 |
Ferguson JK, Roughton FJ. The chemical relationships and physiological importance of carbamino compounds of CO(2) with haemoglobin. The Journal of Physiology. 83: 87-102. PMID 16994616 |
0.198 |
|
| 1934 |
Ferguson JK, Roughton FJ. The direct chemical estimation of carbamino compounds of CO(2) with haemoglobin. The Journal of Physiology. 83: 68-86. PMID 16994615 |
0.209 |
|
| 1933 |
Meldrum NU, Roughton FJ. The state of carbon dioxide in blood. The Journal of Physiology. 80: 143-70. PMID 16994490 |
0.344 |
|
| 1933 |
Meldrum NU, Roughton FJ. Carbonic anhydrase. Its preparation and properties. The Journal of Physiology. 80: 113-42. PMID 16994489 |
0.318 |
|
| 1931 |
Forbes WH, Roughton FJ. The equilibrium between oxygen and haemoglobin: I. The oxygen dissociation curve of dilute blood solutions. The Journal of Physiology. 71: 229-60. PMID 16994173 DOI: 10.1113/jphysiol.1931.sp002729 |
0.398 |
|
| 1928 |
Hartridge H, Roughton FJ. Photographic methods of estimating the percentage saturation of haemoglobin with various gases: I. The ratio of oxyhaemoglobin to carboxyhaemoglobin. The Journal of Physiology. 64: 405-14. PMID 16993931 DOI: 10.1113/jphysiol.1928.sp002450 |
0.232 |
|
| 1927 |
Hartridge H, Roughton FJ. The rate of distribution of dissolved gases between the red blood corpuscle and its fluid environment: Part I. Preliminary experiments on the rate of uptake of oxygen and carbon monoxide by sheep's corpuscles. The Journal of Physiology. 62: 232-42. PMID 16993845 DOI: 10.1113/jphysiol.1927.sp002354 |
0.378 |
|
| 1921 |
Barcroft J, Roughton FJ, Shoji R. The measurement of the oxygen content of the mixed venous blood, and of the volume of blood circulating per minute. The Journal of Physiology. 55: 371-80. PMID 16993523 DOI: 10.1113/jphysiol.1921.sp001982 |
0.346 |
|
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