| Year |
Citation |
Score |
| 2024 |
Abbott JA, Wen H, Liu B, Gupta SS, Iacobucci GJ, Zheng W, Popescu GK. Allosteric inhibition of NMDA receptors by low dose ketamine. Molecular Psychiatry. PMID 39237721 DOI: 10.1038/s41380-024-02729-9 |
0.884 |
|
| 2024 |
Weaver MG, Popescu GK. Correction to: Estimating the Ca Permeability of NMDA Receptors with Whole-Cell Patch-Clamp Electrophysiology. Methods in Molecular Biology (Clifton, N.J.). 2799: C1. PMID 38954366 DOI: 10.1007/978-1-0716-3830-9_17 |
0.5 |
|
| 2024 |
Weaver MG, Popescu GK. Estimating the Ca Permeability of NMDA Receptors with Whole-Cell Patch-Clamp Electrophysiology. Methods in Molecular Biology (Clifton, N.J.). 2799: 177-200. PMID 38727908 DOI: 10.1007/978-1-0716-3830-9_10 |
0.585 |
|
| 2024 |
Iacobucci GJ, Popescu GK. Estimating the Ca Block of NMDA Receptors with Single-Channel Electrophysiology. Methods in Molecular Biology (Clifton, N.J.). 2799: 151-175. PMID 38727907 DOI: 10.1007/978-1-0716-3830-9_9 |
0.859 |
|
| 2023 |
Iacobucci GJ, Popescu GK. Calcium- and calmodulin-dependent inhibition of NMDA receptor currents. Biophysical Journal. PMID 38140727 DOI: 10.1016/j.bpj.2023.12.018 |
0.89 |
|
| 2023 |
Popescu G, Abbott J, Wen H, Liu B, Gupta S, Iacobucci G, Zheng W. Allosteric Site Mediates Inhibition of Tonic NMDA Receptor Activity by Low Dose Ketamine. Research Square. PMID 37790558 DOI: 10.21203/rs.3.rs-3304783/v1 |
0.866 |
|
| 2023 |
Kumar J, Popescu GK, Gantz SC. GluD receptors are functional ion channels. Biophysical Journal. PMID 37177782 DOI: 10.1016/j.bpj.2023.05.012 |
0.514 |
|
| 2022 |
Iacobucci GJ, Liu B, Wen H, Sincox B, Zheng W, Popescu GK. Complex functional phenotypes of NMDA receptor disease variants. Molecular Psychiatry. PMID 36117210 DOI: 10.1038/s41380-022-01774-6 |
0.867 |
|
| 2022 |
Belin S, Maki BA, Catlin J, Rein BA, Popescu GK. Membrane Stretch Gates NMDA Receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35705487 DOI: 10.1523/JNEUROSCI.0350-22.2022 |
0.885 |
|
| 2022 |
Abbott JA, Popescu GK. Homecoming of the estranged GluD channels. Trends in Neurosciences. PMID 35490056 DOI: 10.1016/j.tins.2022.04.001 |
0.857 |
|
| 2021 |
Iacobucci GJ, Wen H, Helou M, Liu B, Zheng W, Popescu GK. Cross-subunit interactions that stabilize open states mediate gating in NMDA receptors. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33384330 DOI: 10.1073/pnas.2007511118 |
0.874 |
|
| 2020 |
Abbott JA, Popescu GK. Hydroxynorketamine Blocks NMDA Receptor Currents by Binding to Closed Receptors. Molecular Pharmacology. PMID 32606205 DOI: 10.1124/mol.120.119784 |
0.885 |
|
| 2019 |
Iacobucci GJ, Popescu GK. Ca-Dependent Inactivation of GluN2A and GluN2B NMDA Receptors Occurs by a Common Kinetic Mechanism. Biophysical Journal. PMID 31629478 DOI: 10.1016/J.Bpj.2019.07.057 |
0.887 |
|
| 2019 |
Iacobucci GJ, Popescu GK. Spatial coupling tunes NMDA receptor responses via Ca diffusion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31519826 DOI: 10.1523/Jneurosci.0901-19.2019 |
0.887 |
|
| 2019 |
Iacobucci GJ, Wen H, Helou M, Zheng W, Popescu GK. Mapping Structural Elements to NMDA Receptor Activation Steps Biophysical Journal. 116: 106a. DOI: 10.1016/J.Bpj.2018.11.607 |
0.848 |
|
| 2018 |
Iacobucci GJ, Popescu GK. Kinetic models for activation and modulation of NMDA receptor subtypes. Current Opinion in Physiology. 2: 114-122. PMID 29978141 DOI: 10.1016/J.Cophys.2018.02.002 |
0.892 |
|
| 2018 |
Iacobucci GJ, Popescu GK. Quantifying Kinetic Transitions between NMDA Receptor Gating Modes Biophysical Journal. 114: 125a. DOI: 10.1016/J.Bpj.2017.11.712 |
0.86 |
|
| 2017 |
Iacobucci GJ, Popescu GK. Resident Calmodulin Primes NMDA Receptors for Ca(2+)-Dependent Inactivation. Biophysical Journal. PMID 28712640 DOI: 10.1016/J.Bpj.2017.06.035 |
0.881 |
|
| 2017 |
Zheng W, Wen H, Iacobucci GJ, Popescu GK. Probing the Structural Dynamics of the NMDA Receptor Activation by Coarse-Grained Modeling. Biophysical Journal. 112: 2589-2601. PMID 28636915 DOI: 10.1016/J.Bpj.2017.04.043 |
0.862 |
|
| 2017 |
Cummings KA, Belin S, Popescu GK. Residues in the GluN1 C-terminal domain control kinetics and pharmacology of GluN1/GluN3A N-methyl-d-aspartate receptors. Neuropharmacology. PMID 28365212 DOI: 10.1016/J.Neuropharm.2017.03.031 |
0.842 |
|
| 2017 |
Iacobucci GJ, Popescu GK. NMDA receptors: linking physiological output to biophysical operation. Nature Reviews. Neuroscience. 18: 236-249. PMID 28303017 DOI: 10.1038/Nrn.2017.24 |
0.892 |
|
| 2017 |
Bajpai VK, Kerosuo L, Tseropoulos G, Cummings KA, Wang X, Lei P, Liu B, Liu S, Popescu G, Bronner ME, Andreadis ST. Reprogramming Postnatal Human Epidermal Keratinocytes toward Functional Neural Crest Fates. Stem Cells (Dayton, Ohio). PMID 28142205 DOI: 10.1002/Stem.2583 |
0.511 |
|
| 2017 |
Maneshi MM, Maki B, Gnanasambandam R, Belin S, Popescu GK, Sachs F, Hua SZ. Mechanical stress activates NMDA receptors in the absence of agonists. Scientific Reports. 7: 39610. PMID 28045032 DOI: 10.1038/Srep39610 |
0.85 |
|
| 2016 |
Cummings KA, Popescu GK. Protons Potentiate GluN1/GluN3A Currents by Attenuating Their Desensitisation. Scientific Reports. 6: 23344. PMID 27000430 DOI: 10.1038/Srep23344 |
0.805 |
|
| 2016 |
Cummings KA, Iacobucci GJ, Popescu GK. Extracting rate constants for nmda receptor gating from one-channel current recordings Neuromethods. 106: 273-299. DOI: 10.1007/978-1-4939-2812-5_18 |
0.873 |
|
| 2015 |
Borschel WF, Cummings KA, Tindell LK, Popescu GK. Contributions to Gating Kinetics by Interactions Unique to NMDA Receptors. The Journal of Biological Chemistry. PMID 26370091 DOI: 10.1074/Jbc.M115.678656 |
0.902 |
|
| 2015 |
Cummings KA, Popescu GK. Glycine-dependent activation of NMDA receptors. The Journal of General Physiology. 145: 513-27. PMID 25964432 DOI: 10.1085/Jgp.201411302 |
0.808 |
|
| 2015 |
Popescu GK. Zinc transporter found attached to N-methyl-D-aspartate receptors. Journal of Neurochemistry. 132: 155-8. PMID 25601392 DOI: 10.1111/jnc.13014 |
0.591 |
|
| 2015 |
Paganelli MA, Popescu GK. Actions of bupivacaine, a widely used local anesthetic, on NMDA receptor responses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 831-42. PMID 25589775 DOI: 10.1523/Jneurosci.3578-14.2015 |
0.877 |
|
| 2015 |
Popescu GK. Accessories assist AMPA receptors to close pockets. The Journal of General Physiology. 145: 17-21. PMID 25512600 DOI: 10.1085/jgp.201411320 |
0.62 |
|
| 2015 |
Popescu GK. Intracellular Domains of NMDA Receptors Control Channel Permeation and Gating Properties Biophysical Journal. 108: 336a. DOI: 10.1016/J.BPJ.2014.11.1831 |
0.645 |
|
| 2015 |
Iacobucci GJ, Maki BA, Popescu GK. Effects of External and Internal Ca2+ on Unitary NMDA Receptor Properties Biophysical Journal. 108: 285a. DOI: 10.1016/J.Bpj.2014.11.1558 |
0.838 |
|
| 2015 |
Cummings KA, Popescu GK. Protons Potentiate GluN1/GluN3A Glycinergic NMDA Receptor Currents Biophysical Journal. 108: 285a. DOI: 10.1016/J.Bpj.2014.11.1556 |
0.641 |
|
| 2015 |
Popescu GK. Ionotropic glutamate receptor technologies Ionotropic Glutamate Receptor Technologies. 1-299. DOI: 10.1007/978-1-4939-2812-5 |
0.466 |
|
| 2014 |
Maki BA, Popescu GK. Extracellular Ca(2+) ions reduce NMDA receptor conductance and gating. The Journal of General Physiology. 144: 379-92. PMID 25348411 DOI: 10.1085/jgp.201411244 |
0.865 |
|
| 2014 |
Maki BA, Cummings KA, Paganelli MA, Murthy SE, Popescu GK. One-channel cell-attached patch-clamp recording. Journal of Visualized Experiments : Jove. PMID 24961614 DOI: 10.3791/51629 |
0.792 |
|
| 2014 |
Aman TK, Maki BA, Ruffino TJ, Kasperek EM, Popescu GK. Separate intramolecular targets for protein kinase A control N-methyl-D-aspartate receptor gating and Ca2+ permeability. The Journal of Biological Chemistry. 289: 18805-17. PMID 24847051 DOI: 10.1074/Jbc.M113.537282 |
0.866 |
|
| 2014 |
Popescu GK. Dynamic plasticity of NMDA receptor-mediated calcium entry in neurons exposed to HIV-tat. Journal of Neurochemistry. 130: 609-11. PMID 24785658 DOI: 10.1111/jnc.12737 |
0.382 |
|
| 2014 |
Murphy JA, Stein IS, Lau CG, Peixoto RT, Aman TK, Kaneko N, Aromolaran K, Saulnier JL, Popescu GK, Sabatini BL, Hell JW, Zukin RS. Phosphorylation of Ser1166 on GluN2B by PKA is critical to synaptic NMDA receptor function and Ca2+ signaling in spines. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 869-79. PMID 24431445 DOI: 10.1523/Jneurosci.4538-13.2014 |
0.834 |
|
| 2013 |
Paganelli MA, Kussius CL, Popescu GK. Role of cross-cleft contacts in NMDA receptor gating. Plos One. 8: e80953. PMID 24278352 DOI: 10.1371/Journal.Pone.0080953 |
0.861 |
|
| 2013 |
Yu H, Popescu GK. Inhibition of GluN2A-containing N-methyl-D-aspartate receptors by 2-naphthoic acid. Molecular Pharmacology. 84: 541-50. PMID 23873856 DOI: 10.1124/Mol.113.087189 |
0.788 |
|
| 2013 |
Maki BA, Cole R, Popescu GK. Two serine residues on GluN2A C-terminal tails control NMDA receptor current decay times. Channels (Austin, Tex.). 7: 126-32. PMID 23503100 DOI: 10.4161/Chan.23968 |
0.878 |
|
| 2013 |
Yu H, Popescu GK. Inhibitory Effects of 2-Naphthoic Acid on the Gating of NMDA Receptors Biophysical Journal. 104: 273a. DOI: 10.1016/J.Bpj.2012.11.1531 |
0.78 |
|
| 2012 |
Borschel WF, Myers JM, Kasperek EM, Smith TP, Graziane NM, Nowak LM, Popescu GK. Gating reaction mechanism of neuronal NMDA receptors. Journal of Neurophysiology. 108: 3105-15. PMID 22993263 DOI: 10.1152/jn.00551.2012 |
0.865 |
|
| 2012 |
Maki BA, Aman TK, Amico-Ruvio SA, Kussius CL, Popescu GK. C-terminal domains of N-methyl-D-aspartic acid receptor modulate unitary channel conductance and gating. The Journal of Biological Chemistry. 287: 36071-80. PMID 22948148 DOI: 10.1074/Jbc.M112.390013 |
0.821 |
|
| 2012 |
Amico-Ruvio SA, Paganelli MA, Myers JM, Popescu GK. Ifenprodil effects on GluN2B-containing glutamate receptors. Molecular Pharmacology. 82: 1074-81. PMID 22936815 DOI: 10.1124/Mol.112.078998 |
0.888 |
|
| 2012 |
Murthy SE, Shogan T, Page JC, Kasperek EM, Popescu GK. Probing the activation sequence of NMDA receptors with lurcher mutations. The Journal of General Physiology. 140: 267-77. PMID 22891278 DOI: 10.1085/jgp.201210786 |
0.858 |
|
| 2012 |
Popescu GK. Modes of glutamate receptor gating. The Journal of Physiology. 590: 73-91. PMID 22106181 DOI: 10.1113/jphysiol.2011.223750 |
0.62 |
|
| 2011 |
Borschel WF, Murthy SE, Kasperek EM, Popescu GK. NMDA receptor activation requires remodelling of intersubunit contacts within ligand-binding heterodimers. Nature Communications. 2: 498. PMID 21988914 DOI: 10.1038/ncomms1512 |
0.901 |
|
| 2011 |
Amico-Ruvio SA, Murthy SE, Smith TP, Popescu GK. Zinc effects on NMDA receptor gating kinetics. Biophysical Journal. 100: 1910-8. PMID 21504727 DOI: 10.1016/j.bpj.2011.02.042 |
0.883 |
|
| 2011 |
Murthy S, Page JC, Preziosi ME, Popescu GK. Subunit Specific Impact of Lurcher Motif Residues on NMDA Receptor Gating Biophysical Journal. 100: 24a. DOI: 10.1016/J.BPJ.2010.12.338 |
0.778 |
|
| 2011 |
Paganelli M, Popescu GK. Role of Salt Bridges within the Ligand Binding Domains of NMDA Receptors During Receptor Activation Biophysical Journal. 100: 270a. DOI: 10.1016/J.Bpj.2010.12.1682 |
0.888 |
|
| 2011 |
Maki BE, Popescu GK. Contributions of Carboxy-Terminal Domains to NMDA Receptor Gating Biophysical Journal. 100: 269a-270a. DOI: 10.1016/J.BPJ.2010.12.1681 |
0.564 |
|
| 2010 |
Kussius CL, Popescu GK. NMDA receptors with locked glutamate-binding clefts open with high efficacy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 12474-9. PMID 20844142 DOI: 10.1523/JNEUROSCI.3337-10.2010 |
0.899 |
|
| 2010 |
Amico-Ruvio SA, Popescu GK. Stationary gating of GluN1/GluN2B receptors in intact membrane patches. Biophysical Journal. 98: 1160-9. PMID 20371315 DOI: 10.1016/j.bpj.2009.12.4276 |
0.894 |
|
| 2010 |
Kussius CL, Popescu AM, Popescu GK. Agonist-specific gating of NMDA receptors. Channels (Austin, Tex.). 4: 78-82. PMID 19934647 DOI: 10.4161/chan.4.2.10523 |
0.896 |
|
| 2010 |
Popescu GK, Murthy S, Borschel WF. Allosteric inhibitors of NMDA receptor functions Pharmaceuticals. 3: 3240-3257. DOI: 10.3390/ph3103240 |
0.888 |
|
| 2010 |
Amico-Ruvio SA, Smith TP, Popescu GK. Gating Effects of a Single-Residue Substitution in the Pore of NMDA Receptors Biophysical Journal. 98: 526a. DOI: 10.1016/j.bpj.2009.12.2855 |
0.881 |
|
| 2010 |
Kussius C, Popescu GK. Glutamate is a Partial Agonist at GluN2A Containing NMDA Receptors Biophysical Journal. 98: 525a. DOI: 10.1016/J.BPJ.2009.12.2853 |
0.893 |
|
| 2010 |
Murthy S, Popescu GK. Effect of lurcher Motif Mutations on NMDA Receptor Kinetics Biophysical Journal. 98: 525a. DOI: 10.1016/J.BPJ.2009.12.2852 |
0.804 |
|
| 2010 |
Borschel WF, Popescu GK. Rearrangements at the Heterodimer Interface are Integral to NMDA Receptor Activation Biophysical Journal. 98: 524a-525a. DOI: 10.1016/J.BPJ.2009.12.2850 |
0.857 |
|
| 2009 |
Kussius CL, Popescu GK. Kinetic basis of partial agonism at NMDA receptors. Nature Neuroscience. 12: 1114-20. PMID 19648915 DOI: 10.1038/nn.2361 |
0.897 |
|
| 2009 |
Kussius CL, Kaur N, Popescu GK. Pregnanolone sulfate promotes desensitization of activated NMDA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6819-27. PMID 19474309 DOI: 10.1523/JNEUROSCI.0281-09.2009 |
0.899 |
|
| 2009 |
Popescu GK. Mechanisms For Information Processing By NMDA Receptors: Insights From Single-channels Biophysical Journal. 96: 565a. DOI: 10.1016/J.BPJ.2008.12.3703 |
0.721 |
|
| 2009 |
Murthy S, Popescu G. Effect of Protons on the NR1/NR2A NMDA Receptor Kinetics Biophysical Journal. 96: 490a. DOI: 10.1016/J.BPJ.2008.12.2529 |
0.836 |
|
| 2009 |
Amico S, Kaur N, Popescu G. Diversity of NR1/NR2B Receptor Gating Kinetics Biophysical Journal. 96: 489a-490a. DOI: 10.1016/J.BPJ.2008.12.2528 |
0.715 |
|
| 2009 |
Kussius C, Myers J, Barnum K, Popescu G. Kinetic Effects of Perturbations in the Ligand Binding Domain of NMDA Receptors Biophysical Journal. 96: 489a. DOI: 10.1016/J.BPJ.2008.12.2527 |
0.86 |
|
| 2009 |
Myers J, Borschel W, Kasperek E, Popescu G. Activation Mechanism of Native NMDA Receptors in Cultured Rat Neurons in Culture Biophysical Journal. 96: 489a. DOI: 10.1016/J.BPJ.2008.12.2526 |
0.847 |
|
| 2008 |
Zhang W, Howe JR, Popescu GK. Distinct gating modes determine the biphasic relaxation of NMDA receptor currents. Nature Neuroscience. 11: 1373-5. PMID 18953348 DOI: 10.1038/Nn.2214 |
0.753 |
|
| 2005 |
Popescu G. Mechanism-based targeting of NMDA receptor functions Cellular and Molecular Life Sciences. 62: 2100-2111. PMID 16132227 DOI: 10.1007/s00018-005-5227-8 |
0.6 |
|
| 2005 |
Popescu G. Principles of N-methyl-D-aspartate receptor allosteric modulation Molecular Pharmacology. 68: 1148-1155. PMID 16033953 DOI: 10.1124/mol.105.013896 |
0.684 |
|
| 2004 |
Popescu G, Robert A, Howe JR, Auerbach A. Reaction mechanism determines NMDA receptor response to repetitive stimulation. Nature. 430: 790-3. PMID 15306812 DOI: 10.1038/nature02775 |
0.802 |
|
| 2004 |
Popescu G, Auerbach A. The NMDA receptor gating machine: lessons from single channels. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 10: 192-8. PMID 15155058 DOI: 10.1177/1073858404263483 |
0.784 |
|
| 2003 |
Popescu G, Auerbach A. Modal gating of NMDA receptors and the shape of their synaptic response. Nature Neuroscience. 6: 476-83. PMID 12679783 DOI: 10.1038/nn1044 |
0.686 |
|
| 2000 |
Popescu G, Napoli JL. Analysis of rat cytosolic 9-cis-retinol dehydrogenase activity and enzymatic characterization of rat ADHII. Biochimica Et Biophysica Acta. 1476: 43-52. PMID 10606766 DOI: 10.1016/S0167-4838(99)00230-7 |
0.506 |
|
| 1995 |
Chai X, Zhai Y, Popescu G, Napoli JL. Cloning of a cDNA for a second retinol dehydrogenase type II. Expression of its mRNA relative to type I. The Journal of Biological Chemistry. 270: 28408-12. PMID 7499345 DOI: 10.1074/Jbc.270.47.28408 |
0.501 |
|
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