| Year |
Citation |
Score |
| 2024 |
Boyer JL, Schachter JB, Sromek SM, Palmer RK, Jacobson KA, Nicholas RA, Harden TK. Avian and Human Homologues of the P2Y Receptor: Pharmacological, Signaling, and Molecular Properties. Drug Development Research. 39: 253-261. PMID 38235168 DOI: 10.1002/(sici)1098-2299(199611/12)39:3/4<253::aid-ddr4>3.0.co;2-q |
0.45 |
|
| 2020 |
Singh A, Turner JM, Tomberg J, Fedarovich A, Unemo M, Nicholas RA, Davies C. Mutations in penicillin-binding protein 2 from cephalosporin-resistant Neisseria gonorrhoeae hinder ceftriaxone acylation by restricting protein dynamics. The Journal of Biological Chemistry. PMID 32253235 DOI: 10.1074/Jbc.Ra120.012617 |
0.358 |
|
| 2019 |
Singh A, Tomberg J, Nicholas RA, Davies C. Recognition of the β-lactam Carboxylate Triggers Acylation of Penicillin-Binding Protein 2. The Journal of Biological Chemistry. PMID 31362987 DOI: 10.1074/Jbc.Ra119.009942 |
0.357 |
|
| 2018 |
Vincent LR, Kerr SR, Tan Y, Tomberg J, Raterman EL, Dunning Hotopp JC, Unemo M, Nicholas RA, Jerse AE.
-Selected Compensatory Mutations Restore the Fitness Cost of MosaicAlleles That Confer Ceftriaxone Resistance in. Mbio. 9. PMID 29615507 DOI: 10.1128/Mbio.01905-17 |
0.355 |
|
| 2017 |
Rouquette-Loughlin CE, Zalucki YM, Dhulipala VL, Balthazar JT, Doyle RG, Nicholas RA, Begum AA, Raterman EL, Jerse AE, Shafer WM. Control of gdhR Expression in Neisseria gonorrhoeae via Autoregulation and a Master Repressor (MtrR) of a Drug Efflux Pump Operon. Mbio. 8. PMID 28400529 DOI: 10.1128/Mbio.00449-17 |
0.309 |
|
| 2017 |
Tomberg J, Fedarovich A, Vincent LR, Jerse AE, Unemo M, Davies C, Nicholas RA. Alanine-501 Mutations in Penicillin-Binding Protein 2 from Neisseria gonorrhoeae: Structure, Mechanism, and Effects on Cephalosporin Resistance and Biological Fitness. Biochemistry. PMID 28145684 DOI: 10.1021/Acs.Biochem.6B01030 |
0.371 |
|
| 2015 |
Nicholas RA. Insights into platelet P2Y12 receptor activation. Blood. 125: 893-5. PMID 25655454 DOI: 10.1182/Blood-2014-12-615336 |
0.377 |
|
| 2015 |
Nandi S, Swanson S, Tomberg J, Nicholas RA. Diffusion of antibiotics through the PilQ secretin in Neisseria gonorrhoeae occurs through the immature, sodium dodecyl sulfate-labile form. Journal of Bacteriology. 197: 1308-21. PMID 25605303 DOI: 10.1128/Jb.02628-14 |
0.346 |
|
| 2014 |
Fedarovich A, Cook E, Tomberg J, Nicholas RA, Davies C. Structural effect of the Asp345a insertion in penicillin-binding protein 2 from penicillin-resistant strains of Neisseria gonorrhoeae. Biochemistry. 53: 7596-603. PMID 25403720 DOI: 10.1021/Bi5011317 |
0.354 |
|
| 2014 |
Morrow GB, Nicholas RA, Kennedy C. UTP is not a biased agonist at human P2Y(11) receptors. Purinergic Signalling. 10: 581-5. PMID 25015314 DOI: 10.1007/S11302-014-9418-3 |
0.508 |
|
| 2013 |
Qi AD, Harden TK, Nicholas RA. Is GPR17 a P2Y/leukotriene receptor? examination of uracil nucleotides, nucleotide sugars, and cysteinyl leukotrienes as agonists of GPR17. The Journal of Pharmacology and Experimental Therapeutics. 347: 38-46. PMID 23908386 DOI: 10.1124/Jpet.113.207647 |
0.495 |
|
| 2013 |
Tomberg J, Unemo M, Ohnishi M, Davies C, Nicholas RA. Identification of amino acids conferring high-level resistance to expanded-spectrum cephalosporins in the penA gene from Neisseria gonorrhoeae strain H041. Antimicrobial Agents and Chemotherapy. 57: 3029-36. PMID 23587946 DOI: 10.1128/Aac.00093-13 |
0.357 |
|
| 2013 |
DuBose DR, Wolff SC, Qi AD, Naruszewicz I, Nicholas RA. Apical targeting of the P2Y(4) receptor is directed by hydrophobic and basic residues in the cytoplasmic tail. American Journal of Physiology. Cell Physiology. 304: C228-39. PMID 23054062 DOI: 10.1152/Ajpcell.00251.2012 |
0.673 |
|
| 2013 |
Tomberg J, Unemo M, Ohnishi M, Davies C, Nicholas R. P1.019 Identification of the Amino Acids Conferring High-Level Resistance to Expanded-Spectrum Cephalosporins in thepenAGene from theNeisseria GonorrhoeaeStrain H041 Sexually Transmitted Infections. 89: A79.2-A79. DOI: 10.1136/Sextrans-2013-051184.0240 |
0.361 |
|
| 2013 |
Tomberg J, Unemo M, Davies C, Nicholas R. P1.018 Analysis of Mosaic Penicillin-Binding Protein 2 Variants with Ala501 Mutations That Confer High-Level Resistance to Expanded-Spectrum Cephalosporins inNeisseria Gonorrhoeae Sexually Transmitted Infections. 89: A79.1-A79. DOI: 10.1136/Sextrans-2013-051184.0239 |
0.346 |
|
| 2013 |
Vincent LR, Unemo M, Duncan M, Nicholas RA, Jerse AE. O21.3 Fitness Studies onNeisseria GonorrhoeaeHarboring MosaicpenAAlleles from Ceftriaxone-Resistant Isolates Predict the Spread of Resistance to Extended-Spectrum Cephalosporins Sexually Transmitted Infections. 89: A67.2-A67. DOI: 10.1136/Sextrans-2013-051184.0205 |
0.334 |
|
| 2012 |
Fedarovich A, Djordjevic KA, Swanson SM, Peterson YK, Nicholas RA, Davies C. High-throughput screening for novel inhibitors of Neisseria gonorrhoeae penicillin-binding protein 2. Plos One. 7: e44918. PMID 23049763 DOI: 10.1371/Journal.Pone.0044918 |
0.313 |
|
| 2012 |
Tomberg J, Temple B, Fedarovich A, Davies C, Nicholas RA. A highly conserved interaction involving the middle residue of the SXN active-site motif is crucial for function of class B penicillin-binding proteins: mutational and computational analysis of PBP 2 from N. gonorrhoeae. Biochemistry. 51: 2775-84. PMID 22397678 DOI: 10.1021/Bi2017987 |
0.377 |
|
| 2012 |
Unemo M, Golparian D, Nicholas R, Ohnishi M, Gallay A, Sednaoui P. High-level cefixime- and ceftriaxone-resistant Neisseria gonorrhoeae in France: novel penA mosaic allele in a successful international clone causes treatment failure. Antimicrobial Agents and Chemotherapy. 56: 1273-80. PMID 22155830 DOI: 10.1128/Aac.05760-11 |
0.337 |
|
| 2011 |
El-Tayeb A, Qi A, Nicholas RA, Müller CE. Structural modifications of UMP, UDP, and UTP leading to subtype-selective agonists for P2Y2, P2Y4, and P2Y6 receptors. Journal of Medicinal Chemistry. 54: 2878-90. PMID 21417463 DOI: 10.1021/Jm1016297 |
0.352 |
|
| 2011 |
Lee CJ, Liang X, Chen X, Zeng D, Joo SH, Chung HS, Barb AW, Swanson SM, Nicholas RA, Li Y, Toone EJ, Raetz CR, Zhou P. Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design. Chemistry & Biology. 18: 38-47. PMID 21167751 DOI: 10.1016/J.Chembiol.2010.11.011 |
0.306 |
|
| 2011 |
Qi AD, Houston-Cohen D, Naruszewicz I, Harden TK, Nicholas RA. Ser352 and Ser354 in the carboxyl terminus of the human P2Y(1) receptor are required for agonist-promoted phosphorylation and internalization in MDCK cells. British Journal of Pharmacology. 162: 1304-13. PMID 21108629 DOI: 10.1111/J.1476-5381.2010.01135.X |
0.531 |
|
| 2010 |
Tomberg J, Unemo M, Davies C, Nicholas RA. Molecular and structural analysis of mosaic variants of penicillin-binding protein 2 conferring decreased susceptibility to expanded-spectrum cephalosporins in Neisseria gonorrhoeae: role of epistatic mutations. Biochemistry. 49: 8062-70. PMID 20704258 DOI: 10.1021/Bi101167X |
0.333 |
|
| 2010 |
Wolff SC, Qi AD, Harden TK, Nicholas RA. Charged residues in the C-terminus of the P2Y1 receptor constitute a basolateral-sorting signal. Journal of Cell Science. 123: 2512-20. PMID 20592187 DOI: 10.1242/Jcs.060723 |
0.747 |
|
| 2010 |
Fedarovich A, Nicholas RA, Davies C. Unusual conformation of the SxN motif in the crystal structure of penicillin-binding protein A from Mycobacterium tuberculosis. Journal of Molecular Biology. 398: 54-65. PMID 20206184 DOI: 10.1016/J.Jmb.2010.02.046 |
0.331 |
|
| 2009 |
Zhao S, Duncan M, Tomberg J, Davies C, Unemo M, Nicholas RA. Genetics of chromosomally mediated intermediate resistance to ceftriaxone and cefixime in Neisseria gonorrhoeae. Antimicrobial Agents and Chemotherapy. 53: 3744-51. PMID 19528266 DOI: 10.1128/Aac.00304-09 |
0.6 |
|
| 2009 |
Hillmann P, Ko GY, Spinrath A, Raulf A, Von Kügelgen I, Wolff SC, Nicholas RA, Kostenis E, Höltje HD, Müller CE. Key determinants of nucleotide-activated G protein-coupled P2Y2 receptor function revealed by chemical and pharmacological experiments, mutagenesis and homology modeling Journal of Medicinal Chemistry. 52: 2762-2775. PMID 19419204 DOI: 10.1021/Jm801442P |
0.758 |
|
| 2009 |
Sesma JI, Esther CR, Kreda SM, Jones L, O'Neal W, Nishihara S, Nicholas RA, Lazarowski ER. Endoplasmic reticulum/golgi nucleotide sugar transporters contribute to the cellular release of UDP-sugar signaling molecules. The Journal of Biological Chemistry. 284: 12572-83. PMID 19276090 DOI: 10.1074/Jbc.M806759200 |
0.326 |
|
| 2008 |
Vernel-Pauillac F, Nandi S, Nicholas RA, Goarant C. Genotyping as a tool for antibiotic resistance surveillance of Neisseria gonorrhoeae in New Caledonia: evidence of a novel genotype associated with reduced penicillin susceptibility. Antimicrobial Agents and Chemotherapy. 52: 3293-300. PMID 18591264 DOI: 10.1128/Aac.00020-08 |
0.317 |
|
| 2008 |
Fricks IP, Maddileti S, Carter RL, Lazarowski ER, Nicholas RA, Jacobson KA, Harden TK. UDP is a competitive antagonist at the human P2Y14 receptor. The Journal of Pharmacology and Experimental Therapeutics. 325: 588-94. PMID 18252808 DOI: 10.1124/Jpet.108.136309 |
0.403 |
|
| 2008 |
Moreschi I, Bruzzone S, Bodrato N, Usai C, Guida L, Nicholas RA, Kassack MU, Zocchi E, De Flora A. NAADP+ is an agonist of the human P2Y11 purinergic receptor. Cell Calcium. 43: 344-55. PMID 17707504 DOI: 10.1016/J.Ceca.2007.06.006 |
0.403 |
|
| 2007 |
Folster JP, Dhulipala V, Nicholas RA, Shafer WM. Differential regulation of ponA and pilMNOPQ expression by the MtrR transcriptional regulatory protein in Neisseria gonorrhoeae. Journal of Bacteriology. 189: 4569-77. PMID 17483228 DOI: 10.1128/Jb.00286-07 |
0.33 |
|
| 2007 |
Lindberg R, Fredlund H, Nicholas R, Unemo M. Neisseria gonorrhoeae isolates with reduced susceptibility to cefixime and ceftriaxone: association with genetic polymorphisms in penA, mtrR, porB1b, and ponA. Antimicrobial Agents and Chemotherapy. 51: 2117-2122. PMID 17420216 DOI: 10.1128/Aac.01604-06 |
0.328 |
|
| 2007 |
Fricks IP, Maddileti S, Lazarowski ER, Nicholas RA, Jacobson KA, Harden TK. UDP is an antagonist at the hP2Y14 receptor The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A424-C |
0.499 |
|
| 2006 |
Fedarovich A, Tomberg J, Nicholas RA, Davies C. Structure of the N-terminal domain of human CEACAM1: binding target of the opacity proteins during invasion of Neisseria meningitidis and N. gonorrhoeae. Acta Crystallographica. Section D, Biological Crystallography. 62: 971-9. PMID 16929097 DOI: 10.1107/S0907444906020737 |
0.36 |
|
| 2006 |
Moreschi I, Bruzzone S, Nicholas RA, Fruscione F, Sturla L, Benvenuto F, Usai C, Meis S, Kassack MU, Zocchi E, De Flora A. Extracellular NAD+ is an agonist of the human P2Y11 purinergic receptor in human granulocytes. The Journal of Biological Chemistry. 281: 31419-29. PMID 16926152 DOI: 10.1074/Jbc.M606625200 |
0.393 |
|
| 2006 |
Powell AJ, Liu ZJ, Nicholas RA, Davies C. Crystal structures of the lytic transglycosylase MltA from N.gonorrhoeae and E.coli: insights into interdomain movements and substrate binding. Journal of Molecular Biology. 359: 122-36. PMID 16618494 DOI: 10.1016/J.Jmb.2006.03.023 |
0.323 |
|
| 2006 |
Olesky M, Zhao S, Rosenberg RL, Nicholas RA. Porin-mediated antibiotic resistance in Neisseria gonorrhoeae: ion, solute, and antibiotic permeation through PIB proteins with penB mutations. Journal of Bacteriology. 188: 2300-8. PMID 16547016 DOI: 10.1128/Jb.188.7.2300-2308.2006 |
0.722 |
|
| 2006 |
Houston D, Ohno M, Nicholas RA, Jacobson KA, Harden TK. [32P]2-iodo-N6-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate ([32P]MRS2500), a novel radioligand for quantification of native P2Y1 receptors. British Journal of Pharmacology. 147: 459-67. PMID 16299552 DOI: 10.1038/Sj.Bjp.0706453 |
0.479 |
|
| 2005 |
Hu M, Nandi S, Davies C, Nicholas RA. High-level chromosomally mediated tetracycline resistance in Neisseria gonorrhoeae results from a point mutation in the rpsJ gene encoding ribosomal protein S10 in combination with the mtrR and penB resistance determinants. Antimicrobial Agents and Chemotherapy. 49: 4327-34. PMID 16189114 DOI: 10.1128/Aac.49.10.4327-4334.2005 |
0.364 |
|
| 2005 |
Zhao S, Tobiason DM, Hu M, Seifert HS, Nicholas RA. The penC mutation conferring antibiotic resistance in Neisseria gonorrhoeae arises from a mutation in the PilQ secretin that interferes with multimer stability. Molecular Microbiology. 57: 1238-51. PMID 16101998 DOI: 10.1111/J.1365-2958.2005.04752.X |
0.364 |
|
| 2005 |
Nicola G, Fedarovich A, Nicholas RA, Davies C. A large displacement of the SXN motif of Cys115-modified penicillin-binding protein 5 from Escherichia coli. The Biochemical Journal. 392: 55-63. PMID 16038617 DOI: 10.1042/Bj20050449 |
0.337 |
|
| 2005 |
Qi AD, Wolff SC, Nicholas RA. The apical targeting signal of the P2Y2 receptor is located in its first extracellular loop. The Journal of Biological Chemistry. 280: 29169-75. PMID 15908695 DOI: 10.1074/Jbc.M501301200 |
0.789 |
|
| 2005 |
Wolff SC, Qi AD, Harden TK, Nicholas RA. Polarized expression of human P2Y receptors in epithelial cells from kidney, lung, and colon. American Journal of Physiology. Cell Physiology. 288: C624-32. PMID 15525684 DOI: 10.1152/Ajpcell.00338.2004 |
0.76 |
|
| 2004 |
Lee SY, Nicholas RA, O'Grady SM. P2Y(1) receptor modulation of endogenous ion channel function in Xenopus oocytes: Involvement of transmembrane domains. Purinergic Signalling. 1: 75-81. PMID 18404403 DOI: 10.1007/S11302-004-4744-5 |
0.442 |
|
| 2004 |
Qi AD, Harden TK, Nicholas RA. GPR80/99, proposed to be the P2Y(15) receptor activated by adenosine and AMP, is not a P2Y receptor. Purinergic Signalling. 1: 67-74. PMID 18404402 DOI: 10.1007/S11302-004-5069-0 |
0.485 |
|
| 2004 |
Stefanova ME, Tomberg J, Davies C, Nicholas RA, Gutheil WG. Overexpression and enzymatic characterization of Neisseria gonorrhoeae penicillin-binding protein 4. European Journal of Biochemistry / Febs. 271: 23-32. PMID 14686916 DOI: 10.1046/J.1432-1033.2003.03886.X |
0.323 |
|
| 2004 |
Herold CL, Qi AD, Harden TK, Nicholas RA. Agonist versus antagonist action of ATP at the P2Y4 receptor is determined by the second extracellular loop. The Journal of Biological Chemistry. 279: 11456-64. PMID 14670966 DOI: 10.1074/Jbc.M301734200 |
0.814 |
|
| 2003 |
Stefanova ME, Tomberg J, Olesky M, Höltje JV, Gutheil WG, Nicholas RA. Neisseria gonorrhoeae penicillin-binding protein 3 exhibits exceptionally high carboxypeptidase and beta-lactam binding activities. Biochemistry. 42: 14614-25. PMID 14661974 DOI: 10.1021/Bi0350607 |
0.701 |
|
| 2003 |
Lee SY, Wolff SC, Nicholas RA, O'Grady SM. P2Y receptors modulate ion channel function through interactions involving the C-terminal domain. Molecular Pharmacology. 63: 878-85. PMID 12644589 DOI: 10.1124/Mol.63.4.878 |
0.741 |
|
| 2002 |
Veal WL, Nicholas RA, Shafer WM. Overexpression of the MtrC-MtrD-MtrE efflux pump due to an mtrR mutation is required for chromosomally mediated penicillin resistance in Neisseria gonorrhoeae. Journal of Bacteriology. 184: 5619-24. PMID 12270819 DOI: 10.1128/Jb.184.20.5619-5624.2002 |
0.355 |
|
| 2002 |
Olesky M, Hobbs M, Nicholas RA. Identification and analysis of amino acid mutations in porin IB that mediate intermediate-level resistance to penicillin and tetracycline in Neisseria gonorrhoeae. Antimicrobial Agents and Chemotherapy. 46: 2811-20. PMID 12183233 DOI: 10.1128/Aac.46.9.2811-2820.2002 |
0.726 |
|
| 2002 |
Ropp PA, Hu M, Olesky M, Nicholas RA. Mutations in ponA, the gene encoding penicillin-binding protein 1, and a novel locus, penC, are required for high-level chromosomally mediated penicillin resistance in Neisseria gonorrhoeae. Antimicrobial Agents and Chemotherapy. 46: 769-77. PMID 11850260 DOI: 10.1128/Aac.46.3.769-777.2002 |
0.725 |
|
| 2001 |
Qi AD, Zambon AC, Insel PA, Nicholas RA. An arginine/glutamine difference at the juxtaposition of transmembrane domain 6 and the third extracellular loop contributes to the markedly different nucleotide selectivities of human and canine P2Y11 receptors. Molecular Pharmacology. 60: 1375-82. PMID 11723245 DOI: 10.1124/Mol.60.6.1375 |
0.564 |
|
| 2001 |
Qi AD, Kennedy C, Harden TK, Nicholas RA. Differential coupling of the human P2Y 11 receptor to phospholipase C and adenylyl cyclase British Journal of Pharmacology. 132: 318-326. PMID 11156592 DOI: 10.1038/Sj.Bjp.0703788 |
0.371 |
|
| 2001 |
Davies C, White SW, Nicholas RA. Crystal structure of a deacylation-defective mutant of penicillin-binding protein 5 at 2.3-Å resolution Journal of Biological Chemistry. 276: 616-623. PMID 10967102 DOI: 10.1074/Jbc.M004471200 |
0.322 |
|
| 2000 |
Kennedy C, Qi AD, Herold CL, Harden TK, Nicholas RA. ATP, an agonist at the rat P2Y(4) receptor, is an antagonist at the human P2Y(4) receptor. Molecular Pharmacology. 57: 926-31. PMID 10779375 |
0.8 |
|
| 1999 |
Hoffmann C, Moro S, Nicholas RA, Harden TK, Jacobson KA. The role of amino acids in extracellular loops of the human P2Y1 receptor in surface expression and activation processes. The Journal of Biological Chemistry. 274: 14639-47. PMID 10329657 DOI: 10.1074/Jbc.274.21.14639 |
0.544 |
|
| 1998 |
Li Q, Olesky M, Palmer RK, Harden TK, Nicholas RA. Evidence that the p2y3 receptor is the avian homologue of the mammalian P2Y6 receptor. Molecular Pharmacology. 54: 541-6. PMID 9730913 DOI: 10.1124/Mol.54.3.541 |
0.788 |
|
| 1998 |
Palmer RK, Boyer JL, Schachter JB, Nicholas RA, Harden TK. Agonist Action of Adenosine Triphosphates at the Human P2Y1 Receptor Molecular Pharmacology. 54: 1118-1123. DOI: 10.1124/Mol.54.6.1118 |
0.478 |
|
| 1997 |
Schachter JB, Boyer JL, Li Q, Nicholas RA, Harden TK. Fidelity in functional coupling of the rat P2Y1 receptor to phospholipase C British Journal of Pharmacology. 122: 1021-1024. PMID 9401764 DOI: 10.1038/Sj.Bjp.0701479 |
0.506 |
|
| 1997 |
Schachter JB, Sromek SM, Nicholas RA, Harden TK. HEK293 human embryonic kidney cells endogenously express the P2Y1 and P2Y2 receptors Neuropharmacology. 36: 1181-1187. PMID 9364473 DOI: 10.1016/S0028-3908(97)00138-X |
0.494 |
|
| 1997 |
Li Q, Schachter JB, Harden TK, Nicholas RA. The 6H1 orphan receptor, claimed to be the p2y5 receptor, does not mediate nucleotide-promoted second messenger responses Biochemical and Biophysical Research Communications. 236: 455-460. PMID 9240460 DOI: 10.1006/Bbrc.1997.6984 |
0.561 |
|
| 1997 |
Herold CL, Li Q, Schachter JB, Harden TK, Nicholas RA. Lack of nucleotide-promoted second messenger signaling responses in 1321N1 cells expressing the proposed P2Y receptor, p2y7. Biochemical and Biophysical Research Communications. 235: 717-21. PMID 9207227 DOI: 10.1006/Bbrc.1997.6884 |
0.813 |
|
| 1997 |
Ropp PA, Nicholas RA. Cloning and characterization of the ponA gene encoding penicillin- binding protein 1 from Neisseria gonorrhoeae and Neisseria meningitidis Journal of Bacteriology. 179: 2783-2787. PMID 9098083 DOI: 10.1128/Jb.179.8.2783-2787.1997 |
0.347 |
|
| 1996 |
Nicholas RA, Lazarowski ER, Watt WC, Li Q, Boyer J, Harden TK. Pharmacological and second messenger signalling selectivities of cloned P2Y receptors. Journal of Autonomic Pharmacology. 16: 319-23. PMID 9131407 DOI: 10.1111/J.1474-8673.1996.Tb00044.X |
0.55 |
|
| 1996 |
O'Grady SM, Elmquist E, Filtz TM, Nicholas RA, Harden TK. A guanine nucleotide-independent inwardly rectifying cation permeability is associated with P2Y1 receptor expression in Xenopus oocytes Journal of Biological Chemistry. 271: 29080-29087. PMID 8910562 DOI: 10.1074/Jbc.271.46.29080 |
0.479 |
|
| 1996 |
Schachter JB, Li Q, Boyer JL, Nicholas RA, Harden TK. Second messenger cascade specificity and pharmacological selectivity of the human P2Y1-purinoceptor British Journal of Pharmacology. 118: 167-173. PMID 8733591 DOI: 10.1111/J.1476-5381.1996.Tb15381.X |
0.42 |
|
| 1996 |
Waldo GL, Paterson A, Boyer JL, Nicholas RA, Harden TK. Molecular cloning, expression and regulatory activity of Gα11- and βγ-subunit-stimulated phospholipase C-β from avian erythrocytes Biochemical Journal. 316: 559-568. PMID 8687401 DOI: 10.1042/Bj3160559 |
0.327 |
|
| 1996 |
Burns EL, Nicholas RA, Price EM. Random mutagenesis of the sheep Na,K-ATPase α1 subunit generating the ouabain-resistant mutant L793P Journal of Biological Chemistry. 271: 15879-15883. PMID 8663108 DOI: 10.1074/Jbc.271.27.15879 |
0.354 |
|
| 1996 |
Wang CC, Schultz DE, Nicholas RA. Localization of a putative second membrane association site in penicillin-binding protein 1B of Escherichia coli. The Biochemical Journal. 316: 149-56. PMID 8645198 DOI: 10.1042/Bj3160149 |
0.317 |
|
| 1996 |
Boyer JL, Schachter JB, Sromek SM, Palmer RK, Jacobson KA, Nicholas RA, Harden TK. Avian and human homologues of the P2Y1 receptor: Pharmacological, signaling, and molecular properties Drug Development Research. 39: 253-261. DOI: 10.1002/(Sici)1098-2299(199611/12)39:3/4<253::Aid-Ddr4>3.0.Co;2-Q |
0.539 |
|
| 1995 |
Kendall Harden T, Boyer JL, Nicholas RA. P2-purinergic receptors: Subtype-associated signalling responses and structure Annual Review of Pharmacology and Toxicology. 35: 541-579. PMID 7598506 DOI: 10.1146/Annurev.Pa.35.040195.002545 |
0.454 |
|
| 1993 |
Maurice DH, Waldo GL, Morris AJ, Nicholas RA, Harden TK. Identification of Gα11 as the phospholipase C-activating G-protein of turkey erythrocytes Biochemical Journal. 290: 765-770. PMID 8457205 DOI: 10.1042/Bj2900765 |
0.346 |
|
| 1991 |
Schultz DE, Spratt BG, Nicholas RA. Expression and purification of a soluble form of penicillin-binding protein 2 from both penicillin-susceptible and penicillin-resistant Neisseria gonorrhoeae. Protein Expression and Purification. 2: 339-49. PMID 1821807 DOI: 10.1016/1046-5928(91)90092-W |
0.383 |
|
| 1990 |
Dingledine R, Myers SJ, Nicholas RA. Molecular biology of mammalian amino acid receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 4: 2636-45. PMID 2161372 DOI: 10.1096/Fasebj.4.9.2161372 |
0.527 |
|
| 1985 |
Nicholas RA, Suzuki H, Hirota Y, Strominger JL. Purification and sequencing of the active site tryptic peptide from penicillin-binding protein 1b of Escherichia coli Biochemistry. 24: 3448-3453. PMID 3899167 DOI: 10.1021/Bi00335A009 |
0.343 |
|
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