| Year |
Citation |
Score |
| 2024 |
Spiess KL, Geden MJ, Romero SE, Hollville E, Hammond ES, Patterson RL, Girardi QB, Deshmukh M. Apoptosis signaling is activated as a transient pulse in neurons. Cell Death and Differentiation. PMID 39462068 DOI: 10.1038/s41418-024-01403-5 |
0.522 |
|
| 2023 |
Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Aqeilan RI, Arama E, Baehrecke EH, ... ... Deshmukh M, et al. Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death and Differentiation. PMID 37100955 DOI: 10.1038/s41418-023-01153-w |
0.388 |
|
| 2022 |
Basundra R, Kapoor S, Hollville E, Kiapour N, Beltran Lopez A, Marie Melchiorre N, Deshmukh M. Constitutive High Expression of NOXA Sensitizes Human Embryonic Stem Cells for Rapid Cell Death. Stem Cells (Dayton, Ohio). 40: 49-58. PMID 35511861 DOI: 10.1093/stmcls/sxab008 |
0.33 |
|
| 2020 |
Hollville E, Joers V, Nakamura A, Swahari V, Tansey MG, Moy SS, Deshmukh M. Characterization of a Cul9-Parkin double knockout mouse model for Parkinson's disease. Scientific Reports. 10: 16886. PMID 33037272 DOI: 10.1038/s41598-020-73854-y |
0.611 |
|
| 2019 |
Hollville E, Romero SE, Deshmukh M. Apoptotic Cell Death Regulation in Neurons. The Febs Journal. PMID 31230407 DOI: 10.1111/Febs.14970 |
0.56 |
|
| 2018 |
Geden MJ, Romero SE, Deshmukh M. Apoptosis versus Axon Pruning: Molecular Intersection of Two Distinct Pathways for Axon Degeneration. Neuroscience Research. PMID 30452947 DOI: 10.1016/J.Neures.2018.11.007 |
0.339 |
|
| 2018 |
Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, ... ... Deshmukh M, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death and Differentiation. PMID 29362479 DOI: 10.1038/S41418-017-0012-4 |
0.462 |
|
| 2017 |
Connolly NMC, Theurey P, Adam-Vizi V, Bazan NG, Bernardi P, Bolaños JP, Culmsee C, Dawson VL, Deshmukh M, Duchen MR, Düssmann H, Fiskum G, Galindo MF, Hardingham GE, Hardwick JM, et al. Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases. Cell Death and Differentiation. PMID 29229998 DOI: 10.1038/S41418-017-0020-4 |
0.386 |
|
| 2017 |
Hollville E, Deshmukh M. Physiological functions of non-apoptotic caspase activity in the nervous system. Seminars in Cell & Developmental Biology. PMID 29199140 DOI: 10.1016/J.Semcdb.2017.11.037 |
0.524 |
|
| 2016 |
Annis RP, Swahari V, Nakamura A, Xie AX, Hammond SM, Deshmukh M. Mature Neurons Dynamically Restrict Apoptosis via Redundant Pre-Mitochondrial Brakes. The Febs Journal. PMID 27797453 DOI: 10.1111/Febs.13944 |
0.499 |
|
| 2016 |
Geden MJ, Deshmukh M. Axon degeneration: context defines distinct pathways. Current Opinion in Neurobiology. 39: 108-115. PMID 27197022 DOI: 10.1016/J.Conb.2016.05.002 |
0.355 |
|
| 2016 |
Nakamura A, Swahari V, Plestant C, Smith I, McCoy E, Smith S, Moy SS, Anton ES, Deshmukh M. Bcl-xL Is Essential for the Survival and Function of Differentiated Neurons in the Cortex That Control Complex Behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 5448-61. PMID 27194326 DOI: 10.1523/Jneurosci.4247-15.2016 |
0.58 |
|
| 2015 |
Swahari V, Nakamura A, Baran-Gale J, Garcia I, Crowther AJ, Sons R, Gershon TR, Hammond S, Sethupathy P, Deshmukh M. Essential Function of Dicer in Resolving DNA Damage in the Rapidly Dividing Cells of the Developing and Malignant Cerebellum. Cell Reports. PMID 26748703 DOI: 10.1016/J.Celrep.2015.12.037 |
0.332 |
|
| 2015 |
Proctor EA, Fee L, Tao Y, Redler RL, Fay JM, Zhang Y, Lv Z, Mercer IP, Deshmukh M, Lyubchenko YL, Dokholyan NV. Nonnative SOD1 trimer is toxic to motor neurons in a model of amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 26719414 DOI: 10.1073/Pnas.1516725113 |
0.386 |
|
| 2015 |
Cliffe AR, Arbuckle JH, Vogel JL, Geden MJ, Rothbart SB, Cusack CL, Strahl BD, Kristie TM, Deshmukh M. Neuronal Stress Pathway Mediating a Histone Methyl/Phospho Switch Is Required for Herpes Simplex Virus Reactivation. Cell Host & Microbe. 18: 649-58. PMID 26651941 DOI: 10.1016/J.Chom.2015.11.007 |
0.426 |
|
| 2015 |
Gama V, Deshmukh M. Life after MOMP. Molecular Cell. 58: 199-201. PMID 25884366 DOI: 10.1016/J.Molcel.2015.03.035 |
0.345 |
|
| 2015 |
Knight ER, Patel EY, Flowers CA, Crowther AJ, Ting JP, Miller CR, Gershon TR, Deshmukh M. ASC deficiency suppresses proliferation and prevents medulloblastoma incidence. Oncogene. 34: 394-402. PMID 24469054 DOI: 10.1038/Onc.2013.577 |
0.744 |
|
| 2014 |
Gama V, Swahari V, Schafer J, Kole AJ, Evans A, Huang Y, Cliffe A, Golitz B, Sciaky N, Pei XH, Xiong Y, Deshmukh M. The E3 ligase PARC mediates the degradation of cytosolic cytochrome c to promote survival in neurons and cancer cells. Science Signaling. 7: ra67. PMID 25028717 DOI: 10.1126/Scisignal.2005309 |
0.819 |
|
| 2014 |
Cusack CL, Annis RP, Kole AJ, Deshmukh M. Neuronal death mechanisms in development and disease Cell Death: Mechanism and Disease. 2147483647: 167-188. DOI: 10.1007/978-1-4614-9302-0_8 |
0.758 |
|
| 2013 |
Gershon TR, Crowther AJ, Liu H, Miller CR, Deshmukh M. Cerebellar granule neuron progenitors are the source of Hk2 in the postnatal cerebellum. Cancer & Metabolism. 1: 15. PMID 24280296 DOI: 10.1186/2049-3002-1-15 |
0.421 |
|
| 2013 |
Crowther AJ, Gama V, Bevilacqua A, Chang SX, Yuan H, Deshmukh M, Gershon TR. Tonic activation of Bax primes neural progenitors for rapid apoptosis through a mechanism preserved in medulloblastoma. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 18098-108. PMID 24227720 DOI: 10.1523/Jneurosci.2602-13.2013 |
0.473 |
|
| 2013 |
Kole AJ, Annis RP, Deshmukh M. Mature neurons: equipped for survival. Cell Death & Disease. 4: e689. PMID 23807218 DOI: 10.1038/Cddis.2013.220 |
0.795 |
|
| 2013 |
Cusack CL, Swahari V, Hampton Henley W, Michael Ramsey J, Deshmukh M. Distinct pathways mediate axon degeneration during apoptosis and axon-specific pruning. Nature Communications. 4: 1876. PMID 23695670 DOI: 10.1038/Ncomms2910 |
0.402 |
|
| 2013 |
Gama V, Deshmukh M. Adenosine: essential for life but licensed to kill. Molecular Cell. 50: 307-8. PMID 23664374 DOI: 10.1016/J.Molcel.2013.04.020 |
0.415 |
|
| 2013 |
Garcia I, Crowther AJ, Gama V, Ryan Miller C, Deshmukh M, Gershon TR. Bax deficiency prolongs cerebellar neurogenesis, accelerates medulloblastoma formation and paradoxically increases both malignancy and differentiation. Oncogene. 32: 2304-14. PMID 22710714 DOI: 10.1038/Onc.2012.248 |
0.485 |
|
| 2012 |
Dumitru R, Gama V, Fagan BM, Bower JJ, Swahari V, Pevny LH, Deshmukh M. Human embryonic stem cells have constitutively active Bax at the Golgi and are primed to undergo rapid apoptosis. Molecular Cell. 46: 573-83. PMID 22560721 DOI: 10.1016/J.Molcel.2012.04.002 |
0.439 |
|
| 2012 |
Uribe V, Wong BK, Graham RK, Cusack CL, Skotte NH, Pouladi MA, Xie Y, Feinberg K, Ou Y, Ouyang Y, Deng Y, Franciosi S, Bissada N, Spreeuw A, Zhang W, ... ... Deshmukh M, et al. Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice. Human Molecular Genetics. 21: 1954-67. PMID 22262731 DOI: 10.1093/Hmg/Dds005 |
0.357 |
|
| 2012 |
Gershon T, Crowther A, Garcia I, Gama V, Allard D, Miller C, Deshmukh M. 95 Medulloblastoma is Primed for Rapid Apoptosis by Constitutively Active Bax: a Unique Vulnerability Which May Be Exploited for Therapeutic Benefit European Journal of Cancer. 48: 30. DOI: 10.1016/S0959-8049(12)71893-2 |
0.445 |
|
| 2011 |
Kole AJ, Knight ER, Deshmukh M. Activation of apoptosis by cytoplasmic microinjection of cytochrome c. Journal of Visualized Experiments : Jove. PMID 21730954 DOI: 10.3791/2773 |
0.792 |
|
| 2011 |
Kole AJ, Swahari V, Hammond SM, Deshmukh M. miR-29b is activated during neuronal maturation and targets BH3-only genes to restrict apoptosis. Genes & Development. 25: 125-30. PMID 21245165 DOI: 10.1101/Gad.1975411 |
0.772 |
|
| 2009 |
West T, Stump M, Lodygensky G, Neil JJ, Deshmukh M, Holtzman DM. Lack of X-linked inhibitor of apoptosis protein leads to increased apoptosis and tissue loss following neonatal brain injury. Asn Neuro. 1. PMID 19570023 DOI: 10.1042/An20090005 |
0.465 |
|
| 2009 |
Smith MI, Huang YY, Deshmukh M. Skeletal muscle differentiation evokes endogenous XIAP to restrict the apoptotic pathway. Plos One. 4: e5097. PMID 19333375 DOI: 10.1371/Journal.Pone.0005097 |
0.708 |
|
| 2008 |
Vaughn AE, Deshmukh M. Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c. Nature Cell Biology. 10: 1477-83. PMID 19029908 DOI: 10.1038/Ncb1807 |
0.804 |
|
| 2007 |
Johnson CE, Huang YY, Parrish AB, Smith MI, Vaughn AE, Zhang Q, Wright KM, Van Dyke T, Wechsler-Reya RJ, Kornbluth S, Deshmukh M. Differential Apaf-1 levels allow cytochrome c to induce apoptosis in brain tumors but not in normal neural tissues. Proceedings of the National Academy of Sciences of the United States of America. 104: 20820-5. PMID 18093951 DOI: 10.1073/Pnas.0709101105 |
0.756 |
|
| 2007 |
Wright KM, Smith MI, Farrag L, Deshmukh M. Chromatin modification of Apaf-1 restricts the apoptotic pathway in mature neurons. The Journal of Cell Biology. 179: 825-32. PMID 18056406 DOI: 10.1083/Jcb.200708086 |
0.766 |
|
| 2007 |
Willingham SB, Bergstralh DT, O'Connor W, Morrison AC, Taxman DJ, Duncan JA, Barnoy S, Venkatesan MM, Flavell RA, Deshmukh M, Hoffman HM, Ting JP. Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC. Cell Host & Microbe. 2: 147-59. PMID 18005730 DOI: 10.1016/J.Chom.2007.07.009 |
0.383 |
|
| 2007 |
Vaughn AE, Deshmukh M. Essential postmitochondrial function of p53 uncovered in DNA damage-induced apoptosis in neurons. Cell Death and Differentiation. 14: 973-81. PMID 17218959 DOI: 10.1038/Sj.Cdd.4402084 |
0.813 |
|
| 2007 |
Smith MI, Deshmukh M. Endoplasmic reticulum stress-induced apoptosis requires bax for commitment and Apaf-1 for execution in primary neurons. Cell Death and Differentiation. 14: 1011-9. PMID 17218955 DOI: 10.1038/Sj.Cdd.4402089 |
0.689 |
|
| 2007 |
Wright KM, Vaughn AE, Deshmukh M. Apoptosome dependent caspase-3 activation pathway is non-redundant and necessary for apoptosis in sympathetic neurons. Cell Death and Differentiation. 14: 625-33. PMID 16932756 DOI: 10.1038/Sj.Cdd.4402024 |
0.826 |
|
| 2006 |
Wright KM, Deshmukh M. Restricting apoptosis for postmitotic cell survival and its relevance to cancer. Cell Cycle (Georgetown, Tex.). 5: 1616-20. PMID 16880745 DOI: 10.4161/Cc.5.15.3129 |
0.66 |
|
| 2006 |
Schafer ZT, Parrish AB, Wright KM, Margolis SS, Marks JR, Deshmukh M, Kornbluth S. Enhanced sensitivity to cytochrome c-induced apoptosis mediated by PHAPI in breast cancer cells. Cancer Research. 66: 2210-8. PMID 16489023 DOI: 10.1158/0008-5472.Can-05-3923 |
0.637 |
|
| 2005 |
Potts MB, Vaughn AE, McDonough H, Patterson C, Deshmukh M. Reduced Apaf-1 levels in cardiomyocytes engage strict regulation of apoptosis by endogenous XIAP. The Journal of Cell Biology. 171: 925-30. PMID 16344307 DOI: 10.1083/Jcb.200504082 |
0.816 |
|
| 2004 |
Deming PB, Schafer ZT, Tashker JS, Potts MB, Deshmukh M, Kornbluth S. Bcr-Abl-mediated protection from apoptosis downstream of mitochondrial cytochrome c release. Molecular and Cellular Biology. 24: 10289-99. PMID 15542838 DOI: 10.1128/Mcb.24.23.10289-10299.2004 |
0.526 |
|
| 2004 |
Wright KM, Linhoff MW, Potts PR, Deshmukh M. Decreased apoptosome activity with neuronal differentiation sets the threshold for strict IAP regulation of apoptosis. The Journal of Cell Biology. 167: 303-13. PMID 15504912 DOI: 10.1083/Jcb.200406073 |
0.729 |
|
| 2003 |
Potts PR, Singh S, Knezek M, Thompson CB, Deshmukh M. Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis. The Journal of Cell Biology. 163: 789-99. PMID 14623868 DOI: 10.1083/Jcb.200307130 |
0.634 |
|
| 2002 |
Deshmukh M, Du C, Wang X, Johnson EM. Exogenous smac induces competence and permits caspase activation in sympathetic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8018-27. PMID 12223555 DOI: 10.1523/Jneurosci.22-18-08018.2002 |
0.724 |
|
| 2002 |
Chang LK, Putcha GV, Deshmukh M, Johnson EM. Mitochondrial involvement in the point of no return in neuronal apoptosis. Biochimie. 84: 223-31. PMID 12022953 DOI: 10.1016/S0300-9084(02)01372-X |
0.604 |
|
| 2002 |
Xia S, Lampe PA, Deshmukh M, Yang A, Brown BS, Rothman SM, Johnson EM, Yu SP. Multiple channel interactions explain the protection of sympathetic neurons from apoptosis induced by nerve growth factor deprivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 114-22. PMID 11756494 DOI: 10.1523/Jneurosci.22-01-00114.2002 |
0.534 |
|
| 2002 |
Harris CA, Deshmukh M, Tsui-Pierchala B, Maroney AC, Johnson EM. Inhibition of the c-Jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 103-13. PMID 11756493 DOI: 10.1523/Jneurosci.22-01-00103.2002 |
0.639 |
|
| 2000 |
Deshmukh M, Kuida K, Johnson EM. Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization. The Journal of Cell Biology. 150: 131-43. PMID 10893262 DOI: 10.1083/Jcb.150.1.131 |
0.695 |
|
| 2000 |
Putcha GV, Deshmukh M, Johnson EM. Inhibition of apoptotic signaling cascades causes loss of trophic factor dependence during neuronal maturation. The Journal of Cell Biology. 149: 1011-8. PMID 10831605 DOI: 10.1083/Jcb.149.5.1011 |
0.691 |
|
| 2000 |
Deshmukh M, Johnson EM. Staurosporine-induced neuronal death: multiple mechanisms and methodological implications. Cell Death and Differentiation. 7: 250-61. PMID 10745270 DOI: 10.1038/Sj.Cdd.4400641 |
0.699 |
|
| 2000 |
Werth JL, Deshmukh M, Cocabo J, Johnson EM, Rothman SM. Reversible physiological alterations in sympathetic neurons deprived of NGF but protected from apoptosis by caspase inhibition or Bax deletion. Experimental Neurology. 161: 203-11. PMID 10683286 DOI: 10.1006/Exnr.1999.7241 |
0.672 |
|
| 2000 |
Han BH, D'Costa A, Back SA, Parsadanian M, Patel S, Shah AR, Gidday JM, Srinivasan A, Deshmukh M, Holtzman DM. BDNF blocks caspase-3 activation in neonatal hypoxia-ischemia. Neurobiology of Disease. 7: 38-53. PMID 10671321 DOI: 10.1006/Nbdi.1999.0275 |
0.441 |
|
| 2000 |
Johnson EM, Deshmukh M. Mitochondrial status of caspase inhibitor-saved neurons: Role of membrane potential in commitment(s) to die Neurobiology of Aging. 21: 282. DOI: 10.1016/S0197-4580(00)83218-2 |
0.617 |
|
| 2000 |
Deshmukh M, Johnson EM. 8. Apoptosis Facts, Research and Intervention in Geriatrics. 2000: 129-142. |
0.557 |
|
| 1999 |
Putcha GV, Deshmukh M, Johnson EM. BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 7476-85. PMID 10460254 DOI: 10.1523/Jneurosci.19-17-07476.1999 |
0.708 |
|
| 1998 |
Deshmukh M. Caspases in ischaemic brain injury and neurodegenerative disease. Apoptosis : An International Journal On Programmed Cell Death. 3: 387-94. PMID 14646471 |
0.338 |
|
| 1998 |
Deshmukh M, Johnson EM. Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c. Neuron. 21: 695-705. PMID 9808457 DOI: 10.1016/S0896-6273(00)80587-5 |
0.694 |
|
| 1998 |
Cheng Y, Deshmukh M, D'Costa A, Demaro JA, Gidday JM, Shah A, Sun Y, Jacquin MF, Johnson EM, Holtzman DM. Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury. The Journal of Clinical Investigation. 101: 1992-9. PMID 9576764 DOI: 10.1172/Jci2169 |
0.579 |
|
| 1997 |
Miller TM, Moulder KL, Knudson CM, Creedon DJ, Deshmukh M, Korsmeyer SJ, Johnson EM. Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death. The Journal of Cell Biology. 139: 205-17. PMID 9314540 DOI: 10.1083/Jcb.139.1.205 |
0.633 |
|
| 1997 |
Holtzman DM, Deshmukh M. Caspases: a treatment target for neurodegenerative disease? Nature Medicine. 3: 954-5. PMID 9288715 DOI: 10.1038/Nm0997-954 |
0.421 |
|
| 1997 |
Deshmukh M, Johnson EM. Programmed cell death in neurons: focus on the pathway of nerve growth factor deprivation-induced death of sympathetic neurons. Molecular Pharmacology. 51: 897-906. PMID 9187255 DOI: 10.1124/Mol.51.6.897 |
0.675 |
|
| 1996 |
Deshmukh M, Vasilakos J, Deckwerth TL, Lampe PA, Shivers BD, Johnson EM. Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases. The Journal of Cell Biology. 135: 1341-54. PMID 8947555 DOI: 10.1083/Jcb.135.5.1341 |
0.645 |
|
| 1996 |
Johnson EM, Deckwerth TL, Deshmukh M. Neuronal death in developmental models: possible implications in neuropathology. Brain Pathology (Zurich, Switzerland). 6: 397-409. PMID 8944313 DOI: 10.1111/J.1750-3639.1996.Tb00872.X |
0.672 |
|
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