Britta J. Eickholt - Publications

Affiliations: 
King's College London, London, UK 
Area:
Developmental Neurobiology

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Brosig A, Fuchs J, Ipek F, Kroon C, Schrötter S, Vadhvani M, Polyzou A, Ledderose J, van Diepen M, Holzhütter HG, Trimbuch T, Gimber N, Schmoranzer J, Lieberam I, Rosenmund C, ... ... Eickholt BJ, et al. The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches. Cell Reports. 29: 2028-2040.e8. PMID 31722215 DOI: 10.1016/j.celrep.2019.10.039  0.36
2015 An W, Jackson RE, Hunter P, Gögel S, van Diepen M, Liu K, Meyer MP, Eickholt BJ. Engineering FKBP-Based Destabilizing Domains to Build Sophisticated Protein Regulation Systems. Plos One. 10: e0145783. PMID 26717575 DOI: 10.1371/journal.pone.0145783  1
2015 Leondaritis G, Eickholt BJ. Short Lives with Long-Lasting Effects: Filopodia Protrusions in Neuronal Branching Morphogenesis. Plos Biology. 13: e1002241. PMID 26334727 DOI: 10.1371/journal.pbio.1002241  1
2015 Sonego M, Oberoi M, Stoddart J, Gajendra S, Hendricusdottir R, Oozeer F, Worth DC, Hobbs C, Eickholt BJ, Gordon-Weeks PR, Doherty P, Lalli G. Drebrin regulates neuroblast migration in the postnatal mammalian brain. Plos One. 10: e0126478. PMID 25945928 DOI: 10.1371/journal.pone.0126478  1
2015 Spinelli L, Black FM, Berg JN, Eickholt BJ, Leslie NR. Functionally distinct groups of inherited PTEN mutations in autism and tumour syndromes. Journal of Medical Genetics. 52: 128-34. PMID 25527629 DOI: 10.1136/jmedgenet-2014-102803  1
2015 Sonego M, Oberoi M, Stoddart J, Gajendra S, Hendricusdottir R, Oozeer F, Worth DC, Hobbs C, Eickholt BJ, Gordon-Weeks PR, Doherty P, Lalli G. Drebrin regulates neuroblast migration in the postnatal mammalian brain Plos One. 10. DOI: 10.1371/journal.pone.0126478  1
2014 Hsia HE, Kumar R, Luca R, Takeda M, Courchet J, Nakashima J, Wu S, Goebbels S, An W, Eickholt BJ, Polleux F, Rotin D, Wu H, Rossner MJ, Bagni C, et al. Ubiquitin E3 ligase Nedd4-1 acts as a downstream target of PI3K/PTEN-mTORC1 signaling to promote neurite growth. Proceedings of the National Academy of Sciences of the United States of America. 111: 13205-10. PMID 25157163 DOI: 10.1073/pnas.1400737111  1
2014 Pulido R, Baker SJ, Barata JT, Carracedo A, Cid VJ, Chin-Sang ID, Davé V, den Hertog J, Devreotes P, Eickholt BJ, Eng C, Furnari FB, Georgescu MM, Gericke A, Hopkins B, et al. A unified nomenclature and amino acid numbering for human PTEN. Science Signaling. 7: pe15. PMID 24985344 DOI: 10.1126/scisignal.2005560  1
2014 Kreis P, Leondaritis G, Lieberam I, Eickholt BJ. Subcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disorders. Frontiers in Molecular Neuroscience. 7: 23. PMID 24744697 DOI: 10.3389/fnmol.2014.00023  1
2013 Kreis P, Hendricusdottir R, Kay L, Papageorgiou IE, van Diepen M, Mack T, Ryves J, Harwood A, Leslie NR, Kann O, Parsons M, Eickholt BJ. Phosphorylation of the actin binding protein Drebrin at S647 is regulated by neuronal activity and PTEN. Plos One. 8: e71957. PMID 23940795 DOI: 10.1371/journal.pone.0071957  1
2013 Berglund FM, Weerasinghe NR, Davidson L, Lim JC, Eickholt BJ, Leslie NR. Disruption of epithelial architecture caused by loss of PTEN or by oncogenic mutant p110α/PIK3CA but not by HER2 or mutant AKT1. Oncogene. 32: 4417-26. PMID 23085752 DOI: 10.1038/onc.2012.459  1
2012 Chiara F, Badaloni A, Croci L, Yeh ML, Cariboni A, Hoerder-Suabedissen A, Consalez GG, Eickholt B, Shimogori T, Parnavelas JG, Rakić S. Early B-cell factors 2 and 3 (EBF2/3) regulate early migration of Cajal-Retzius cells from the cortical hem. Developmental Biology. 365: 277-89. PMID 22421355 DOI: 10.1016/j.ydbio.2012.02.034  1
2011 Mack TG, Eickholt BJ. New WAVEs in neuronal PI3K signalling. The Embo Journal. 30: 4693-5. PMID 22126817 DOI: 10.1038/emboj.2011.405  1
2011 Kay L, Humphreys L, Eickholt BJ, Burrone J. Neuronal activity drives matching of pre- and postsynaptic function during synapse maturation. Nature Neuroscience. 14: 688-90. PMID 21532580 DOI: 10.1038/nn.2826  1
2011 Hernández-Miranda LR, Cariboni A, Faux C, Ruhrberg C, Cho JH, Cloutier JF, Eickholt BJ, Parnavelas JG, Andrews WD. Robo1 regulates semaphorin signaling to guide the migration of cortical interneurons through the ventral forebrain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6174-87. PMID 21508241 DOI: 10.1523/JNEUROSCI.5464-10.2011  1
2010 Waite K, Eickholt BJ. The neurodevelopmental implications of PI3K signaling. Current Topics in Microbiology and Immunology. 346: 245-65. PMID 20582530 DOI: 10.1007/82_2010_82  1
2010 Kreis P, van Diepen MT, Eickholt BJ. Regulation of PTEN in neurons by myosin-based transport mechanisms. Advances in Enzyme Regulation. 50: 119-24. PMID 19895832 DOI: 10.1016/j.advenzreg.2009.10.014  1
2009 van Diepen MT, Parsons M, Downes CP, Leslie NR, Hindges R, Eickholt BJ. MyosinV controls PTEN function and neuronal cell size. Nature Cell Biology. 11: 1191-6. PMID 19767745 DOI: 10.1038/ncb1961  1
2009 Jackson RE, Eickholt BJ. Semaphorin signalling. Current Biology : Cb. 19: R504-7. PMID 19602408 DOI: 10.1016/j.cub.2009.04.055  1
2008 Eickholt BJ. Functional diversity and mechanisms of action of the semaphorins. Development (Cambridge, England). 135: 2689-94. PMID 18660466 DOI: 10.1242/dev.019968  1
2008 Schwarz Q, Vieira JM, Howard B, Eickholt BJ, Ruhrberg C. Neuropilin 1 and 2 control cranial gangliogenesis and axon guidance through neural crest cells. Development (Cambridge, England). 135: 1605-13. PMID 18356247 DOI: 10.1242/dev.015412  1
2008 Cosker KE, Shadan S, van Diepen M, Morgan C, Li M, Allen-Baume V, Hobbs C, Doherty P, Cockcroft S, Eickholt BJ. Regulation of PI3K signalling by the phosphatidylinositol transfer protein PITPalpha during axonal extension in hippocampal neurons. Journal of Cell Science. 121: 796-803. PMID 18285448 DOI: 10.1242/jcs.019166  1
2008 van Diepen MT, Eickholt BJ. Function of PTEN during the formation and maintenance of neuronal circuits in the brain. Developmental Neuroscience. 30: 59-64. PMID 18075255 DOI: 10.1159/000109852  1
2007 Eickholt BJ, Ahmed AI, Davies M, Papakonstanti EA, Pearce W, Starkey ML, Bilancio A, Need AC, Smith AJ, Hall SM, Hamers FP, Giese KP, Bradbury EJ, Vanhaesebroeck B. Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase. Plos One. 2: e869. PMID 17846664 DOI: 10.1371/journal.pone.0000869  1
2007 Ahmed A, Eickholt BJ. Intracellular kinases in semaphorin signaling. Advances in Experimental Medicine and Biology. 600: 24-37. PMID 17607944 DOI: 10.1007/978-0-387-70956-7_3  1
2007 Fazzari P, Penachioni J, Gianola S, Rossi F, Eickholt BJ, Maina F, Alexopoulou L, Sottile A, Comoglio PM, Flavell RA, Tamagnone L. Plexin-B1 plays a redundant role during mouse development and in tumour angiogenesis. Bmc Developmental Biology. 7: 55. PMID 17519029 DOI: 10.1186/1471-213X-7-55  1
2007 Cosker KE, Eickholt BJ. Phosphoinositide 3-kinase signalling events controlling axonal morphogenesis. Biochemical Society Transactions. 35: 207-10. PMID 17371239 DOI: 10.1042/BST0350207  1
2006 Cole AR, Causeret F, Yadirgi G, Hastie CJ, McLauchlan H, McManus EJ, Hernández F, Eickholt BJ, Nikolic M, Sutherland C. Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo. The Journal of Biological Chemistry. 281: 16591-8. PMID 16611631 DOI: 10.1074/jbc.M513344200  1
2006 Chadborn NH, Ahmed AI, Holt MR, Prinjha R, Dunn GA, Jones GE, Eickholt BJ. PTEN couples Sema3A signalling to growth cone collapse. Journal of Cell Science. 119: 951-7. PMID 16495486 DOI: 10.1242/jcs.02801  1
2005 Osborne NJ, Begbie J, Chilton JK, Schmidt H, Eickholt BJ. Semaphorin/neuropilin signaling influences the positioning of migratory neural crest cells within the hindbrain region of the chick. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 232: 939-49. PMID 15729704 DOI: 10.1002/dvdy.20258  1
2005 Williams G, Eickholt BJ, Maison P, Prinjha R, Walsh FS, Doherty P. A complementary peptide approach applied to the design of novel semaphorin/neuropilin antagonists. Journal of Neurochemistry. 92: 1180-90. PMID 15715668 DOI: 10.1111/j.1471-4159.2004.02950.x  1
2005 Eickholt BJ, Towers GJ, Ryves WJ, Eikel D, Adley K, Ylinen LM, Chadborn NH, Harwood AJ, Nau H, Williams RS. Effects of valproic acid derivatives on inositol trisphosphate depletion, teratogenicity, glycogen synthase kinase-3beta inhibition, and viral replication: a screening approach for new bipolar disorder drugs derived from the valproic acid core structure. Molecular Pharmacology. 67: 1426-33. PMID 15687223 DOI: 10.1124/mol.104.009308  1
2004 Williams R, Ryves WJ, Dalton EC, Eickholt B, Shaltiel G, Agam G, Harwood AJ. A molecular cell biology of lithium Biochemical Society Transactions. 32: 799-802. PMID 15494019 DOI: 10.1042/BST0320799  1
2004 Brown M, Jacobs T, Eickholt B, Ferrari G, Teo M, Monfries C, Qi RZ, Leung T, Lim L, Hall C. α2-chimaerin, cyclin-dependent kinase 5/p35, and its target collapsin response mediator protein-2 are essential components in semaphorin 3A-induced growth-cone collapse Journal of Neuroscience. 24: 8994-9004. PMID 15483118 DOI: 10.1523/JNEUROSCI.3184-04.2004  1
2004 Bron R, Eickholt BJ, Vermeren M, Fragale N, Cohen J. Functional knockdown of neuropilin-1 in the developing chick nervous system by siRNA hairpins phenocopies genetic ablation in the mouse. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 230: 299-308. PMID 15162508 DOI: 10.1002/dvdy.20043  1
2004 Eickholt BJ, Williams RSB, Harwood AJ. Mood stabilizers and the cell biology of neuronal growth cones Clinical Neuroscience Research. 4: 189-199. DOI: 10.1016/j.cnr.2004.09.011  1
2003 Bachelder RE, Lipscomb EA, Lin X, Wendt MA, Chadborn NH, Eickholt BJ, Mercurio AM. Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells. Cancer Research. 63: 5230-3. PMID 14500350  1
2002 Chadborn N, Eickholt B, Doherty P, Bolsover S. Direct measurement of local raised subplasmalemmal calcium concentrations in growth cones advancing on an N-cadherin substrate. The European Journal of Neuroscience. 15: 1891-8. PMID 12099895 DOI: 10.1046/j.1460-9568.2002.02033.x  1
2002 Eickholt BJ, Walsh FS, Doherty P. An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling. The Journal of Cell Biology. 157: 211-7. PMID 11956225 DOI: 10.1083/jcb.200201098  1
2002 van Horck FP, Lavazais E, Eickholt BJ, Moolenaar WH, Divecha N. Essential role of type I(alpha) phosphatidylinositol 4-phosphate 5-kinase in neurite remodeling. Current Biology : Cb. 12: 241-5. PMID 11839279 DOI: 10.1016/S0960-9822(01)00660-1  1
2001 Eickholt BJ, Graham A, Lumsden A, Wizenmann A. Rhombomere interactions control the segmental differentiation of hindbrain neurons. Molecular and Cellular Neurosciences. 18: 141-8. PMID 11520176 DOI: 10.1006/mcne.2001.1014  1
2001 Utton MA, Eickholt B, Howell FV, Wallis J, Doherty P. Soluble N-cadherin stimulates fibroblast growth factor receptor dependent neurite outgrowth and N-cadherin and the fibroblast growth factor receptor co-cluster in cells. Journal of Neurochemistry. 76: 1421-30. PMID 11238727 DOI: 10.1046/j.1471-4159.2001.00140.x  1
1999 Västrik I, Eickholt BJ, Walsh FS, Ridley A, Doherty P. Sema3A-induced growth-cone collapse is mediated by Rac1 amino acids 17-32. Current Biology : Cb. 9: 991-8. PMID 10508610 DOI: 10.1016/S0960-9822(99)80447-3  1
1999 Eickholt BJ, Mackenzie SL, Graham A, Walsh FS, Doherty P. Evidence for collapsin-1 functioning in the control of neural crest migration in both trunk and hindbrain regions. Development (Cambridge, England). 126: 2181-9. PMID 10207143  1
1997 Eickholt BJ, Morrow R, Walsh FS, Doherty P. Structural features of collapsin required for biological activity and distribution of binding sites in the developing chick. Molecular and Cellular Neurosciences. 9: 358-71. PMID 9361274 DOI: 10.1006/mcne.1997.0636  1
1995 Pollerberg GE, Eickholt BJ. Target preference of embryonic retina cells and retinal cell lines is cell-autonomous, position-specific, early determined and heritable. The European Journal of Neuroscience. 7: 1431-41. PMID 7551169 DOI: 10.1111/j.1460-9568.1995.tb01138.x  1
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