Timo Kirschstein - Publications

Physiology University of Rostock, Rostock, Mecklenburg-Vorpommern, Germany 

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Müller S, Kartheus M, Hendinger E, Hübner DC, Schnell E, Rackow S, Bertsche A, Köhling R, Kirschstein T. Persistent Kv7.2/7.3 downregulation in the rat pilocarpine model of mesial temporal lobe epilepsy. Epilepsy Research. 200: 107296. PMID 38219422 DOI: 10.1016/j.eplepsyres.2024.107296  0.61
2023 Petereit C, Porath K, Rackow S, Kernig K, Hakenberg OW, Köhling R, Kirschstein T. Age-dependent effects of the β adrenoceptor agonist CL316,243 on human and rat detrusor muscle strips. Pflugers Archiv : European Journal of Physiology. PMID 37993748 DOI: 10.1007/s00424-023-02877-x  0.551
2023 Lange F, Porath K, Sellmann T, Einsle A, Jaster R, Linnebacher M, Köhling R, Kirschstein T. Direct-Current Electrical Field Stimulation of Patient-Derived Colorectal Cancer Cells. Biology. 12. PMID 37508461 DOI: 10.3390/biology12071032  0.539
2023 Kirschstein T, Köhling R. Functional changes in neuronal circuits due to antibody-driven autoimmune response. Neurobiology of Disease. 184: 106221. PMID 37414365 DOI: 10.1016/j.nbd.2023.106221  0.603
2022 Frerker B, Fiedler S, Kirschstein T, Lange F, Porath K, Sellmann T, Kutzner L, Wilde F, Moosmann J, Köhling R, Hildebrandt G, Schültke E. Effects of Microbeam Irradiation on Rodent Esophageal Smooth Muscle Contraction. Cells. 12. PMID 36611969 DOI: 10.3390/cells12010176  0.534
2022 Küpper M, Porath K, Sellmann T, Bien CG, Köhling R, Kirschstein T. GluN2B inhibition rescues impaired potentiation and epileptogenicity at associational-commissural CA3 synapses in a model of anti-NMDAR encephalitis. Neuroscience Letters. 795: 137031. PMID 36574811 DOI: 10.1016/j.neulet.2022.137031  0.629
2022 Hörnschemeyer J, Kirschstein T, Reichart G, Sasse C, Venus J, Einsle A, Porath K, Linnebacher M, Köhling R, Lange F. Studies on Biological and Molecular Effects of Small-Molecule Kinase Inhibitors on Human Glioblastoma Cells and Organotypic Brain Slices. Life (Basel, Switzerland). 12. PMID 36013437 DOI: 10.3390/life12081258  0.558
2022 Lange F, Kirschstein T, Davis J, Paino J, Barnes M, Klein M, Porath K, Stöhlmacher P, Fiedler S, Frank M, Köhling R, Hildebrandt G, Hausermann D, Lerch M, Schültke E. Microbeam irradiation of the beating rodent heart: an ex vivo study of acute and subacute effects on cardiac function. International Journal of Radiation Oncology, Biology, Physics. PMID 35533907 DOI: 10.1016/j.ijrobp.2022.05.001  0.515
2022 Lange F, Venus J, Shams Esfand Abady D, Porath K, Einsle A, Sellmann T, Neubert V, Reichart G, Linnebacher M, Köhling R, Kirschstein T. Galvanotactic Migration of Glioblastoma and Brain Metastases Cells. Life (Basel, Switzerland). 12. PMID 35455071 DOI: 10.3390/life12040580  0.565
2021 Laker D, Tolle F, Stegen M, Heerdegen M, Köhling R, Kirschstein T, Wolfart J. K7 and K6 Channels Shape the Slow AHP in Mouse Dentate Gyrus Granule Cells and Control Burst-like Firing Behavior. Neuroscience. 467: 56-72. PMID 34048798 DOI: 10.1016/j.neuroscience.2021.05.025  0.581
2021 Müller L, Kirschstein T, Köhling R, Kuhla A, Teipel S. Neuronal Hyperexcitability in APPSWE/PS1dE9 Mouse Models of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 33843674 DOI: 10.3233/JAD-201540  0.536
2020 Lange F, Hartung J, Liebelt C, Boisserée J, Resch T, Porath K, Hörnschemeyer J, Reichart G, Sellmann T, Neubert V, Kriesen S, Hildebrandt G, Schültke E, Köhling R, Kirschstein T. Perampanel Add-on to Standard Radiochemotherapy Promotes Neuroprotection in a Rodent F98 Glioma Model. Frontiers in Neuroscience. 14: 598266. PMID 33328869 DOI: 10.3389/fnins.2020.598266  0.564
2020 Madadi A, Wolfart J, Lange F, Brehme H, Linnebacher M, Bräuer AU, Büttner A, Freiman T, Henker C, Einsle A, Rackow S, Köhling R, Kirschstein T, Müller S. Correlation between Kir4.1 expression and barium-sensitive currents in rat and human glioma cell lines. Neuroscience Letters. 135481. PMID 33161102 DOI: 10.1016/j.neulet.2020.135481  0.575
2020 Kirschstein T, Sadkiewicz E, Hund-Göschel G, Becker J, Guli X, Müller S, Rohde M, Hübner DC, Brehme H, Kolbaske S, Porath K, Sellmann T, Großmann A, Wittstock M, Syrbe S, et al. Stereotactically Injected Kv1.2 and CASPR2 Antisera Cause Differential Effects on CA1 Synaptic and Cellular Excitability, but Both Enhance the Vulnerability to Pro-epileptic Conditions. Frontiers in Synaptic Neuroscience. 12: 13. PMID 32269520 DOI: 10.3389/Fnsyn.2020.00013  0.614
2020 Schulze F, Müller S, Guli X, Schumann L, Brehme H, Riffert T, Rohde M, Goerss D, Rackow S, Einsle A, Kirschstein T, Köhling R. CK2 Inhibition Prior to Status Epilepticus Persistently Enhances K2 Function in CA1 Which Slows Down Disease Progression. Frontiers in Cellular Neuroscience. 14: 33. PMID 32174814 DOI: 10.3389/Fncel.2020.00033  0.626
2020 Frerker B, Rohde M, Müller S, Bien CG, Köhling R, Kirschstein T. Distinct Effects of Stereotactically Injected Human Cerebrospinal Fluid Containing Glutamic Acid Decarboxylase Antibodies into the Hippocampus of Rats on the Development of Spontaneous Epileptic Activity. Brain Sciences. 10. PMID 32098388 DOI: 10.3390/Brainsci10020123  0.627
2019 Rohde M, Ziebart J, Kirschstein T, Sellmann T, Porath K, Kühl F, Delenda B, Bahls C, van Rienen U, Bader R, Köhling R. Human Osteoblast Migration in DC Electrical Fields Depends on Store Operated Ca-Release and Is Correlated to Upregulation of Stretch-Activated TRPM7 Channels. Frontiers in Bioengineering and Biotechnology. 7: 422. PMID 31921825 DOI: 10.3389/Fbioe.2019.00422  0.605
2019 Ni H, Kirschstein T, Norwood BA, Hsieh CL. Editorial: The Developmental Seizure-Induced Hippocampal Mossy Fiber Sprouting: Target for Epilepsy Therapies? Frontiers in Neurology. 10: 1212. PMID 31849807 DOI: 10.3389/Fneur.2019.01212  0.316
2019 Mayer J, Kirschstein T, Resch T, Porath K, Krause BJ, Köhling R, Lange F. Perampanel attenuates epileptiform phenotype in C6 glioma. Neuroscience Letters. 134629. PMID 31734290 DOI: 10.1016/J.Neulet.2019.134629  0.649
2019 Zschorlich VR, Hillebrecht M, Tanjour T, Qi F, Behrendt F, Kirschstein T, Köhling R. Repetitive Peripheral Magnetic Nerve Stimulation (rPMS) as Adjuvant Therapy Reduces Skeletal Muscle Reflex Activity. Frontiers in Neurology. 10: 930. PMID 31507528 DOI: 10.3389/Fneur.2019.00930  0.575
2019 Kersten M, Rabbe T, Blome R, Porath K, Sellmann T, Bien CG, Köhling R, Kirschstein T. Novel Object Recognition in Rats With NMDAR Dysfunction in CA1 After Stereotactic Injection of Anti-NMDAR Encephalitis Cerebrospinal Fluid. Frontiers in Neurology. 10: 586. PMID 31231304 DOI: 10.3389/Fneur.2019.00586  0.622
2019 Lange F, Weßlau K, Porath K, Hörnschemeyer J, Bergner C, Krause BJ, Mullins CS, Linnebacher M, Köhling R, Kirschstein T. AMPA receptor antagonist perampanel affects glioblastoma cell growth and glutamate release in vitro. Plos One. 14: e0211644. PMID 30716120 DOI: 10.1371/Journal.Pone.0211644  0.62
2018 Reichart G, Mayer J, Zehm C, Kirschstein T, Tokay T, Lange F, Baltrusch S, Tiedge M, Fuellen G, Ibrahim S, Köhling R. Mitochondrial complex IV mutation increases ROS production and reduces lifespan in aged mice. Acta Physiologica (Oxford, England). e13214. PMID 30376218 DOI: 10.1111/Apha.13214  0.541
2018 Bajorat R, Porath K, Kuhn J, Goßla E, Goerss D, Sellmann T, Köhling R, Kirschstein T. Oral administration of the casein kinase 2 inhibitor TBB leads to persistent K2.2 channel up-regulation in the epileptic CA1 area and cortex, but lacks anti-seizure efficacy in the pilocarpine epilepsy model. Epilepsy Research. 147: 42-50. PMID 30219695 DOI: 10.1016/J.Eplepsyres.2018.08.012  0.631
2018 Blome R, Bach W, Guli X, Porath K, Sellmann T, Bien CG, Köhling R, Kirschstein T. Differentially Altered NMDAR Dependent and Independent Long-Term Potentiation in the CA3 Subfield in a Model of Anti-NMDAR Encephalitis. Frontiers in Synaptic Neuroscience. 10: 26. PMID 30108497 DOI: 10.3389/Fnsyn.2018.00026  0.642
2018 Mader F, Müller S, Krause L, Springer A, Kernig K, Protzel C, Porath K, Rackow S, Wittstock T, Frank M, Hakenberg OW, Köhling R, Kirschstein T. Hyperpolarization-Activated Cyclic Nucleotide-Gated Non-selective (HCN) Ion Channels Regulate Human and Murine Urinary Bladder Contractility. Frontiers in Physiology. 9: 753. PMID 29971015 DOI: 10.3389/Fphys.2018.00753  0.6
2018 Müller S, Guli X, Hey J, Einsle A, Pfanz D, Sudmann V, Kirschstein T, Köhling R. Acute epileptiform activity induced by gabazine involves proteasomal rather than lysosomal degradation of KCa2.2 channels. Neurobiology of Disease. PMID 29330041 DOI: 10.1016/J.Nbd.2018.01.005  0.645
2018 Lange F, Porath K, Hartung J, Resch T, Weßlau K, Hörnschemeyer J, Linnebacher M, Schültke E, Kirschstein T, Köhling R. P18. Effekte von Perampanel auf die Gliom-assoziierte Epilepsie Clinical Neurophysiology. 129: e74. DOI: 10.1016/J.Clinph.2018.04.660  0.651
2017 Dammann F, Kirschstein T, Guli X, Müller S, Porath K, Rohde M, Tokay T, Köhling R. Bidirectional shift of group III metabotropic glutamate receptor-mediated synaptic depression in the epileptic hippocampus. Epilepsy Research. PMID 29224956 DOI: 10.1016/J.Eplepsyres.2017.12.002  0.623
2017 Neumann AM, Abele J, Kirschstein T, Engelmann R, Sellmann T, Köhling R, Müller-Hilke B. Mycophenolate mofetil prevents the delayed T cell response after pilocarpine-induced status epilepticus in mice. Plos One. 12: e0187330. PMID 29182639 DOI: 10.1371/Journal.Pone.0187330  0.576
2017 Rehberg M, Kirschstein T, Guli X, Müller S, Rohde M, Franz D, Tokay T, Köhling R. Functional Metaplasticity of Hippocampal Schaffer Collateral-CA1 Synapses Is Reversed in Chronically Epileptic Rats. Neural Plasticity. 2017: 8087401. PMID 29098091 DOI: 10.1155/2017/8087401  0.614
2017 Li S, Kumar T P, Joshee S, Kirschstein T, Subburaju S, Khalili JS, Kloepper J, Du C, Elkhal A, Szabó G, Jain RK, Köhling R, Vasudevan A. Endothelial cell-derived GABA signaling modulates neuronal migration and postnatal behavior. Cell Research. PMID 29086765 DOI: 10.1038/Cr.2017.135  0.585
2016 Hackert JK, Müller L, Rohde M, Bien CG, Köhling R, Kirschstein T. Anti-GAD65 Containing Cerebrospinal Fluid Does not Alter GABAergic Transmission. Frontiers in Cellular Neuroscience. 10: 130. PMID 27242441 DOI: 10.3389/Fncel.2016.00130  0.646
2016 Mader F, Krause L, Tokay T, Hakenberg OW, Köhling R, Kirschstein T. P2Y receptor-mediated transient relaxation of rat longitudinal ileum preparations involves phospholipase C activation, intracellular Ca(2+) release and SK channel activation. Acta Pharmacologica Sinica. PMID 27018177 DOI: 10.1038/Aps.2015.137  0.617
2016 Bajorat R, Goerss D, Brenndörfer L, Schwabe L, Köhling R, Kirschstein T. Interplay between interictal spikes and behavioral seizures in young, but not aged pilocarpine-treated epileptic rats. Epilepsy & Behavior : E&B. 57: 90-94. PMID 26926072 DOI: 10.1016/J.Yebeh.2016.01.014  0.617
2016 Guli X, Tokay T, Kirschstein T, Köhling R. Status Epilepticus Enhances Depotentiation after Fully Established LTP in an NMDAR-Dependent but GluN2B-Independent Manner. Neural Plasticity. 2016: 6592038. PMID 26881126 DOI: 10.1155/2016/6592038  0.636
2016 Avchalumov Y, Kirschstein T, Köhling R. Loss of GABAergic control of corticostriatal LTP following status epilepticus Translational Brain Rhythmicity. 1. DOI: 10.15761/TBR.1000102  0.559
2015 Würdemann T, Kersten M, Tokay T, Guli X, Kober M, Rohde M, Porath K, Sellmann T, Bien CG, Köhling R, Kirschstein T. Stereotactic injection of cerebrospinal fluid from anti-NMDA receptor encephalitis into rat dentate gyrus impairs NMDA receptor function. Brain Research. PMID 26721688 DOI: 10.1016/J.Brainres.2015.12.027  0.649
2015 Kirschstein T, Sahre T, Kernig K, Protzel C, Porath K, Köhling R, Hakenberg OW. Inverse relationship of Rho kinase and myosin-light chain kinase expression in the aging human detrusor smooth muscle. Bmc Urology. 15: 104. PMID 26468005 DOI: 10.1186/S12894-015-0098-2  0.578
2015 Kirschstein T, Köhling R. Animal models of tumour-associated epilepsy. Journal of Neuroscience Methods. PMID 26092434 DOI: 10.1016/J.Jneumeth.2015.06.008  0.606
2015 Weller J, Pose M, Protzel C, Mader F, Porath K, Köhling R, Hakenberg OW, Kirschstein T. Age-related decrease of adenosine-mediated relaxation in rat detrusor is a result of A2B receptor downregulation. International Journal of Urology : Official Journal of the Japanese Urological Association. 22: 322-9. PMID 25728851 DOI: 10.1111/Iju.12679  0.59
2015 Kirschstein T, Tokay T, Rohde M, Zschorlich V, Köhling R. V39. Repetitive magnetic stimulation (rMS) leads to NMDA receptor-dependent metaplasticity in hippocampal slices in vitro Clinical Neurophysiology. 126: e85-e86. DOI: 10.1016/J.Clinph.2015.04.117  0.646
2014 Tokay T, Kirschstein T, Rohde M, Zschorlich V, Köhling R. NMDA receptor-dependent metaplasticity by high-frequency magnetic stimulation. Neural Plasticity. 2014: 684238. PMID 25405036 DOI: 10.1155/2014/684238  0.638
2014 Avchalumov Y, Sander SE, Richter F, Porath K, Hamann M, Bode C, Kirschstein T, Köhling R, Richter A. Role of striatal NMDA receptor subunits in a model of paroxysmal dystonia. Experimental Neurology. 261: 677-84. PMID 25139804 DOI: 10.1016/J.Expneurol.2014.08.012  0.361
2014 Brehme H, Kirschstein T, Schulz R, Köhling R. In vivo treatment with the casein kinase 2 inhibitor 4,5,6,7- tetrabromotriazole augments the slow afterhyperpolarizing potential and prevents acute epileptiform activity. Epilepsia. 55: 175-83. PMID 24596964 DOI: 10.1111/Epi.12474  0.402
2014 Kirschstein T, Protzel C, Porath K, Sellmann T, Köhling R, Hakenberg OW. Age-dependent contribution of Rho kinase in carbachol-induced contraction of human detrusor smooth muscle in vitro. Acta Pharmacologica Sinica. 35: 74-81. PMID 24122009 DOI: 10.1038/Aps.2013.126  0.314
2013 Klatte K, Kirschstein T, Otte D, Pothmann L, Müller L, Tokay T, Kober M, Uebachs M, Zimmer A, Beck H. Impaired D-serine-mediated cotransmission mediates cognitive dysfunction in epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13066-80. PMID 23926260 DOI: 10.1523/Jneurosci.5423-12.2013  0.364
2013 Avchalumov Y, Volkmann CE, Rückborn K, Hamann M, Kirschstein T, Richter A, Köhling R. Persistent changes of corticostriatal plasticity in dt(sz) mutant hamsters after age-dependent remission of dystonia. Neuroscience. 250: 60-9. PMID 23827309 DOI: 10.1016/J.Neuroscience.2013.06.048  0.331
2013 Müller L, Tokay T, Porath K, Köhling R, Kirschstein T. Enhanced NMDA receptor-dependent LTP in the epileptic CA1 area via upregulation of NR2B. Neurobiology of Disease. 54: 183-93. PMID 23313317 DOI: 10.1016/J.Nbd.2012.12.011  0.426
2012 Kirschstein T. Synaptic plasticity and learning in animal models of tuberous sclerosis complex. Neural Plasticity. 2012: 279834. PMID 22848848 DOI: 10.1155/2012/279834  0.33
2012 Guli X, Tokay T, Rohde M, Bender RA, Köhling R, Kirschstein T. ZD7288 enhances long-term depression at early postnatal medial perforant path-granule cell synapses. Neural Plasticity. 2012: 237913. PMID 22792490 DOI: 10.1155/2012/237913  0.341
2012 Avchalumov Y, Kirschstein T, Lukas J, Luo J, Wree A, Rolfs A, Köhling R. Increased excitability and compromised long-term potentiation in the neocortex of NPC1(-/-) mice. Brain Research. 1444: 20-6. PMID 22325094 DOI: 10.1016/J.Brainres.2012.01.019  0.364
2012 Rohde J, Kirschstein T, Wilkars W, Müller L, Tokay T, Porath K, Bender RA, Köhling R. Upregulation of presynaptic mGluR2, but not mGluR3 in the epileptic medial perforant path. Neuropharmacology. 62: 1867-73. PMID 22202905 DOI: 10.1016/J.Neuropharm.2011.12.012  0.378
2012 Kernig K, Kirschstein T, Würdemann T, Rohde M, Köhling R. The afterhyperpolarizing potential following a train of action potentials is suppressed in an acute epilepsy model in the rat Cornu Ammonis 1 area. Neuroscience. 201: 288-96. PMID 22100272 DOI: 10.1016/J.Neuroscience.2011.11.008  0.377
2012 Kirschstein T, Mikkat S, Mikkat U, Bender R, Kreutzer M, Schulz R, Köhling R, Glocker MO. The 27-kDa heat shock protein (HSP27) is a reliable hippocampal marker of full development of pilocarpine-induced status epilepticus. Epilepsy Research. 98: 35-43. PMID 21920704 DOI: 10.1016/J.Eplepsyres.2011.08.015  0.345
2012 Schulz R, Kirschstein T, Brehme H, Porath K, Mikkat U, Köhling R. Network excitability in a model of chronic temporal lobe epilepsy critically depends on SK channel-mediated AHP currents. Neurobiology of Disease. 45: 337-47. PMID 21889592 DOI: 10.1016/J.Nbd.2011.08.019  0.373
2011 Barmashenko G, Hefft S, Aertsen A, Kirschstein T, Köhling R. Positive shifts of the GABAA receptor reversal potential due to altered chloride homeostasis is widespread after status epilepticus. Epilepsia. 52: 1570-8. PMID 21899534 DOI: 10.1111/J.1528-1167.2011.03247.X  0.619
2011 Bajorat R, Wilde M, Sellmann T, Kirschstein T, Köhling R. Seizure frequency in pilocarpine-treated rats is independent of circadian rhythm. Epilepsia. 52: e118-22. PMID 21801169 DOI: 10.1055/S-0032-1301453  0.332
2011 Avchalumov Y, Kirschstein T, Köhling R. Altered physiology and pharmacology in the corticostriatal system in a model of temporal lobe epilepsy. Epilepsia. 52: 151-7. PMID 21070218 DOI: 10.1111/J.1528-1167.2010.02779.X  0.396
2011 Protzel C, Kirschstein T, Porath K, Sellmann T, Köhling R, Hakenberg O. UP-03.203 Role of Myosin Light Chain Kinase in Carbachol-Induced Contractions of Human Detrusor Mooth Muscle Urology. 78: S412. DOI: 10.1016/J.Urology.2011.07.1291  0.569
2009 Tokay T, Rohde M, Krabbe S, Rehberg M, Bender RA, Köhling R, Kirschstein T. HCN1 channels constrain DHPG-induced LTD at hippocampal Schaffer collateral-CA1 synapses. Learning & Memory (Cold Spring Harbor, N.Y.). 16: 769-76. PMID 19940037 DOI: 10.1101/Lm.1556009  0.393
2009 Rohde M, Tokay T, Köhling R, Kirschstein T. GABA(A) receptor inhibition does not affect mGluR-dependent LTD at hippocampal Schaffer collateral-CA1 synapses. Neuroscience Letters. 467: 20-5. PMID 19800390 DOI: 10.1016/J.Neulet.2009.09.053  0.37
2009 Kirschstein T, Köhling R. What is the source of the EEG? Clinical Eeg and Neuroscience. 40: 146-9. PMID 19715175 DOI: 10.1177/155005940904000305  0.336
2009 Kirschstein T, Rehberg M, Bajorat R, Tokay T, Porath K, Köhling R. High K+-induced contraction requires depolarization-induced Ca2+ release from internal stores in rat gut smooth muscle. Acta Pharmacologica Sinica. 30: 1123-31. PMID 19578389 DOI: 10.1038/Aps.2009.98  0.35
2009 Tokay T, Holl N, Kirschstein T, Zschorlich V, Köhling R. High-frequency magnetic stimulation induces long-term potentiation in rat hippocampal slices. Neuroscience Letters. 461: 150-4. PMID 19539714 DOI: 10.1016/J.Neulet.2009.06.032  0.385
2007 Bender RA, Kirschstein T, Kretz O, Brewster AL, Richichi C, Rüschenschmidt C, Shigemoto R, Beck H, Frotscher M, Baram TZ. Localization of HCN1 channels to presynaptic compartments: novel plasticity that may contribute to hippocampal maturation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4697-706. PMID 17460082 DOI: 10.1523/Jneurosci.4699-06.2007  0.312
2006 von der Brelie C, Waltereit R, Zhang L, Beck H, Kirschstein T. Impaired synaptic plasticity in a rat model of tuberous sclerosis. The European Journal of Neuroscience. 23: 686-92. PMID 16487150 DOI: 10.1111/J.1460-9568.2006.04594.X  0.378
2005 Zhang L, Kirschstein T, Sommersberg B, Merkens M, Manahan-Vaughan D, Elgersma Y, Beck H. Hippocampal synaptic metaplasticity requires inhibitory autophosphorylation of Ca2+/calmodulin-dependent kinase II. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7697-707. PMID 16107656 DOI: 10.1523/Jneurosci.2086-05.2005  0.375
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