Timo Kirschstein - Publications

Physiology University of Rostock, Rostock, Mecklenburg-Vorpommern, Germany 

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lange F, Weßlau K, Porath K, Hörnschemeyer J, Bergner C, Krause BJ, Mullins CS, Linnebacher M, Köhling R, Kirschstein T. AMPA receptor antagonist perampanel affects glioblastoma cell growth and glutamate release in vitro. Plos One. 14: e0211644. PMID 30716120 DOI: 10.1371/journal.pone.0211644  0.6
2018 Reichart G, Mayer J, Zehm C, Kirschstein T, Tokay T, Lange F, Baltrusch S, Tiedge M, Fuellen G, Ibrahim S, Köhling R. Mitochondrial complex IV mutation increases ROS production and reduces lifespan in aged mice. Acta Physiologica (Oxford, England). e13214. PMID 30376218 DOI: 10.1111/apha.13214  0.6
2018 Bajorat R, Porath K, Kuhn J, Goßla E, Goerss D, Sellmann T, Köhling R, Kirschstein T. Oral administration of the casein kinase 2 inhibitor TBB leads to persistent K2.2 channel up-regulation in the epileptic CA1 area and cortex, but lacks anti-seizure efficacy in the pilocarpine epilepsy model. Epilepsy Research. 147: 42-50. PMID 30219695 DOI: 10.1016/j.eplepsyres.2018.08.012  0.6
2018 Blome R, Bach W, Guli X, Porath K, Sellmann T, Bien CG, Köhling R, Kirschstein T. Differentially Altered NMDAR Dependent and Independent Long-Term Potentiation in the CA3 Subfield in a Model of Anti-NMDAR Encephalitis. Frontiers in Synaptic Neuroscience. 10: 26. PMID 30108497 DOI: 10.3389/fnsyn.2018.00026  0.6
2018 Mader F, Müller S, Krause L, Springer A, Kernig K, Protzel C, Porath K, Rackow S, Wittstock T, Frank M, Hakenberg OW, Köhling R, Kirschstein T. Hyperpolarization-Activated Cyclic Nucleotide-Gated Non-selective (HCN) Ion Channels Regulate Human and Murine Urinary Bladder Contractility. Frontiers in Physiology. 9: 753. PMID 29971015 DOI: 10.3389/fphys.2018.00753  0.6
2018 Müller S, Guli X, Hey J, Einsle A, Pfanz D, Sudmann V, Kirschstein T, Köhling R. Acute epileptiform activity induced by gabazine involves proteasomal rather than lysosomal degradation of KCa2.2 channels. Neurobiology of Disease. PMID 29330041 DOI: 10.1016/j.nbd.2018.01.005  0.6
2017 Dammann F, Kirschstein T, Guli X, Müller S, Porath K, Rohde M, Tokay T, Köhling R. Bidirectional shift of group III metabotropic glutamate receptor-mediated synaptic depression in the epileptic hippocampus. Epilepsy Research. PMID 29224956 DOI: 10.1016/j.eplepsyres.2017.12.002  0.6
2017 Neumann AM, Abele J, Kirschstein T, Engelmann R, Sellmann T, Köhling R, Müller-Hilke B. Mycophenolate mofetil prevents the delayed T cell response after pilocarpine-induced status epilepticus in mice. Plos One. 12: e0187330. PMID 29182639 DOI: 10.1371/journal.pone.0187330  0.6
2017 Rehberg M, Kirschstein T, Guli X, Müller S, Rohde M, Franz D, Tokay T, Köhling R. Functional Metaplasticity of Hippocampal Schaffer Collateral-CA1 Synapses Is Reversed in Chronically Epileptic Rats. Neural Plasticity. 2017: 8087401. PMID 29098091 DOI: 10.1155/2017/8087401  0.6
2017 Li S, Kumar T P, Joshee S, Kirschstein T, Subburaju S, Khalili JS, Kloepper J, Du C, Elkhal A, Szabó G, Jain RK, Köhling R, Vasudevan A. Endothelial cell-derived GABA signaling modulates neuronal migration and postnatal behavior. Cell Research. PMID 29086765 DOI: 10.1038/cr.2017.135  0.6
2016 Hackert JK, Müller L, Rohde M, Bien CG, Köhling R, Kirschstein T. Anti-GAD65 Containing Cerebrospinal Fluid Does not Alter GABAergic Transmission. Frontiers in Cellular Neuroscience. 10: 130. PMID 27242441 DOI: 10.3389/fncel.2016.00130  0.6
2016 Mader F, Krause L, Tokay T, Hakenberg OW, Köhling R, Kirschstein T. P2Y receptor-mediated transient relaxation of rat longitudinal ileum preparations involves phospholipase C activation, intracellular Ca(2+) release and SK channel activation. Acta Pharmacologica Sinica. PMID 27018177 DOI: 10.1038/aps.2015.137  0.6
2016 Bajorat R, Goerss D, Brenndörfer L, Schwabe L, Köhling R, Kirschstein T. Interplay between interictal spikes and behavioral seizures in young, but not aged pilocarpine-treated epileptic rats. Epilepsy & Behavior : E&B. 57: 90-94. PMID 26926072 DOI: 10.1016/j.yebeh.2016.01.014  0.6
2016 Guli X, Tokay T, Kirschstein T, Köhling R. Status Epilepticus Enhances Depotentiation after Fully Established LTP in an NMDAR-Dependent but GluN2B-Independent Manner. Neural Plasticity. 2016: 6592038. PMID 26881126 DOI: 10.1155/2016/6592038  0.6
2016 Kirschstein T, Wolters A, Lenz JH, Fröhlich S, Hakenberg O, Kundt G, Darmüntzel M, Hecker M, Altiner A, Müller-Hilke B. An algorithm for calculating exam quality as a basis for performance-based allocation of funds at medical schools Gms Zeitschrift Fur Medizinische Ausbildung. 33. DOI: 10.3205/zma001043  0.6
2015 Würdemann T, Kersten M, Tokay T, Guli X, Kober M, Rohde M, Porath K, Sellmann T, Bien CG, Köhling R, Kirschstein T. Stereotactic injection of cerebrospinal fluid from anti-NMDA receptor encephalitis into rat dentate gyrus impairs NMDA receptor function. Brain Research. PMID 26721688 DOI: 10.1016/j.brainres.2015.12.027  0.6
2015 Kirschstein T, Sahre T, Kernig K, Protzel C, Porath K, Köhling R, Hakenberg OW. Inverse relationship of Rho kinase and myosin-light chain kinase expression in the aging human detrusor smooth muscle. Bmc Urology. 15: 104. PMID 26468005 DOI: 10.1186/s12894-015-0098-2  0.6
2015 Kirschstein T, Köhling R. Animal models of tumour-associated epilepsy. Journal of Neuroscience Methods. PMID 26092434 DOI: 10.1016/j.jneumeth.2015.06.008  0.6
2015 Rösche J, Piek J, Hildebrandt G, Grossmann A, Kirschstein T, Benecke R. Perampanel in the treatment of a patient with glioblastoma multiforme without IDH1 mutation and without MGMT promotor methylation Fortschritte Der Neurologie Psychiatrie. 83: 286-289. PMID 26018396 DOI: 10.1055/s-0034-1399459  0.6
2015 Weller J, Pose M, Protzel C, Mader F, Porath K, Köhling R, Hakenberg OW, Kirschstein T. Age-related decrease of adenosine-mediated relaxation in rat detrusor is a result of A2B receptor downregulation. International Journal of Urology : Official Journal of the Japanese Urological Association. 22: 322-9. PMID 25728851 DOI: 10.1111/iju.12679  0.6
2014 Fröscher W, Kirschstein T, Rösche J. Anticonvulsant therapy for brain tumour-related epilepsy Fortschritte Der Neurologie Psychiatrie. 82: 678-690. PMID 25489755 DOI: 10.1055/s-0034-1385475  0.6
2014 Tokay T, Kirschstein T, Rohde M, Zschorlich V, Köhling R. NMDA receptor-dependent metaplasticity by high-frequency magnetic stimulation. Neural Plasticity. 2014: 684238. PMID 25405036 DOI: 10.1155/2014/684238  0.6
2014 Avchalumov Y, Sander SE, Richter F, Porath K, Hamann M, Bode C, Kirschstein T, Köhling R, Richter A. Role of striatal NMDA receptor subunits in a model of paroxysmal dystonia. Experimental Neurology. 261: 677-84. PMID 25139804 DOI: 10.1016/j.expneurol.2014.08.012  0.6
2014 Brehme H, Kirschstein T, Schulz R, Köhling R. In vivo treatment with the casein kinase 2 inhibitor 4,5,6,7- tetrabromotriazole augments the slow afterhyperpolarizing potential and prevents acute epileptiform activity. Epilepsia. 55: 175-83. PMID 24596964 DOI: 10.1111/epi.12474  0.6
2014 Müller L, Müller S, Sellmann T, Groeneweg L, Tokay T, Köhling R, Kirschstein T. Effects of oxygen insufflation during pilocarpine-induced status epilepticus on mortality, tissue damage and seizures. Epilepsy Research. 108: 90-7. PMID 24315663 DOI: 10.1016/j.eplepsyres.2013.10.017  0.6
2014 Kirschstein T, Protzel C, Porath K, Sellmann T, Köhling R, Hakenberg OW. Age-dependent contribution of Rho kinase in carbachol-induced contraction of human detrusor smooth muscle in vitro. Acta Pharmacologica Sinica. 35: 74-81. PMID 24122009 DOI: 10.1038/aps.2013.126  0.6
2013 Klatte K, Kirschstein T, Otte D, Pothmann L, Müller L, Tokay T, Kober M, Uebachs M, Zimmer A, Beck H. Impaired D-serine-mediated cotransmission mediates cognitive dysfunction in epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13066-80. PMID 23926260 DOI: 10.1523/JNEUROSCI.5423-12.2013  0.6
2013 Avchalumov Y, Volkmann CE, Rückborn K, Hamann M, Kirschstein T, Richter A, Köhling R. Persistent changes of corticostriatal plasticity in dt(sz) mutant hamsters after age-dependent remission of dystonia. Neuroscience. 250: 60-9. PMID 23827309 DOI: 10.1016/j.neuroscience.2013.06.048  0.6
2013 Müller L, Tokay T, Porath K, Köhling R, Kirschstein T. Enhanced NMDA receptor-dependent LTP in the epileptic CA1 area via upregulation of NR2B. Neurobiology of Disease. 54: 183-93. PMID 23313317 DOI: 10.1016/j.nbd.2012.12.011  0.6
2012 Kirschstein T. Synaptic plasticity and learning in animal models of tuberous sclerosis complex. Neural Plasticity. 2012: 279834. PMID 22848848 DOI: 10.1155/2012/279834  0.6
2012 Guli X, Tokay T, Rohde M, Bender RA, Köhling R, Kirschstein T. ZD7288 enhances long-term depression at early postnatal medial perforant path-granule cell synapses. Neural Plasticity. 2012: 237913. PMID 22792490 DOI: 10.1155/2012/237913  0.6
2012 Avchalumov Y, Kirschstein T, Lukas J, Luo J, Wree A, Rolfs A, Köhling R. Increased excitability and compromised long-term potentiation in the neocortex of NPC1(-/-) mice. Brain Research. 1444: 20-6. PMID 22325094 DOI: 10.1016/j.brainres.2012.01.019  0.6
2012 Rohde J, Kirschstein T, Wilkars W, Müller L, Tokay T, Porath K, Bender RA, Köhling R. Upregulation of presynaptic mGluR2, but not mGluR3 in the epileptic medial perforant path. Neuropharmacology. 62: 1867-73. PMID 22202905 DOI: 10.1016/j.neuropharm.2011.12.012  0.6
2012 Kernig K, Kirschstein T, Würdemann T, Rohde M, Köhling R. The afterhyperpolarizing potential following a train of action potentials is suppressed in an acute epilepsy model in the rat Cornu Ammonis 1 area. Neuroscience. 201: 288-96. PMID 22100272 DOI: 10.1016/j.neuroscience.2011.11.008  0.6
2012 Kirschstein T, Mikkat S, Mikkat U, Bender R, Kreutzer M, Schulz R, Köhling R, Glocker MO. The 27-kDa heat shock protein (HSP27) is a reliable hippocampal marker of full development of pilocarpine-induced status epilepticus. Epilepsy Research. 98: 35-43. PMID 21920704 DOI: 10.1016/j.eplepsyres.2011.08.015  0.6
2012 Schulz R, Kirschstein T, Brehme H, Porath K, Mikkat U, Köhling R. Network excitability in a model of chronic temporal lobe epilepsy critically depends on SK channel-mediated AHP currents. Neurobiology of Disease. 45: 337-47. PMID 21889592 DOI: 10.1016/j.nbd.2011.08.019  0.6
2011 Barmashenko G, Hefft S, Aertsen A, Kirschstein T, Köhling R. Positive shifts of the GABAA receptor reversal potential due to altered chloride homeostasis is widespread after status epilepticus. Epilepsia. 52: 1570-8. PMID 21899534 DOI: 10.1111/j.1528-1167.2011.03247.x  0.6
2011 Bajorat R, Wilde M, Sellmann T, Kirschstein T, Köhling R. Seizure frequency in pilocarpine-treated rats is independent of circadian rhythm. Epilepsia. 52: e118-22. PMID 21801169 DOI: 10.1111/j.1528-1167.2011.03200.x  0.6
2011 Avchalumov Y, Kirschstein T, Köhling R. Altered physiology and pharmacology in the corticostriatal system in a model of temporal lobe epilepsy. Epilepsia. 52: 151-7. PMID 21070218 DOI: 10.1111/j.1528-1167.2010.02779.x  0.6
2009 Tokay T, Rohde M, Krabbe S, Rehberg M, Bender RA, Köhling R, Kirschstein T. HCN1 channels constrain DHPG-induced LTD at hippocampal Schaffer collateral-CA1 synapses. Learning & Memory (Cold Spring Harbor, N.Y.). 16: 769-76. PMID 19940037 DOI: 10.1101/lm.1556009  0.6
2009 Rohde M, Tokay T, Köhling R, Kirschstein T. GABA(A) receptor inhibition does not affect mGluR-dependent LTD at hippocampal Schaffer collateral-CA1 synapses. Neuroscience Letters. 467: 20-5. PMID 19800390 DOI: 10.1016/j.neulet.2009.09.053  0.6
2009 Kirschstein T, Dammann F, Klostermann J, Rehberg M, Tokay T, Schubert R, Köhling R. Dopamine induces contraction in the proximal, but relaxation in the distal rat isolated small intestine. Neuroscience Letters. 465: 21-6. PMID 19733212 DOI: 10.1016/j.neulet.2009.08.080  0.6
2009 Kirschstein T, Köhling R. What is the source of the EEG? Clinical Eeg and Neuroscience. 40: 146-9. PMID 19715175  0.6
2009 Kirschstein T, Rehberg M, Bajorat R, Tokay T, Porath K, Köhling R. High K+-induced contraction requires depolarization-induced Ca2+ release from internal stores in rat gut smooth muscle. Acta Pharmacologica Sinica. 30: 1123-31. PMID 19578389 DOI: 10.1038/aps.2009.98  0.6
2009 Tokay T, Holl N, Kirschstein T, Zschorlich V, Köhling R. High-frequency magnetic stimulation induces long-term potentiation in rat hippocampal slices. Neuroscience Letters. 461: 150-4. PMID 19539714 DOI: 10.1016/j.neulet.2009.06.032  0.6
2008 Kirschstein T. How is the EEG generated? Neurophysiologie-Labor. 30: 29-37. DOI: 10.1016/j.neulab.2008.05.003  0.6
2008 Kirschstein T, Bien CG, Bender RA. Symposium "Potassium channels in epilepsy" on the occasion of the Annual Meeting of the German Physiological Society, March 5, 2008 in Cologne Zeitschrift Fur Epileptologie. 21: 153-155. DOI: 10.1007/s10309-008-0321-1  0.6
2007 Kirschstein T, Bauer M, Müller L, Rüschenschmidt C, Reitze M, Becker AJ, Schoch S, Beck H. Loss of metabotropic glutamate receptor-dependent long-term depression via downregulation of mGluR5 after status epilepticus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7696-704. PMID 17634364 DOI: 10.1523/JNEUROSCI.4572-06.2007  0.6
2007 Bender RA, Kirschstein T, Kretz O, Brewster AL, Richichi C, Rüschenschmidt C, Shigemoto R, Beck H, Frotscher M, Baram TZ. Localization of HCN1 channels to presynaptic compartments: novel plasticity that may contribute to hippocampal maturation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4697-706. PMID 17460082 DOI: 10.1523/JNEUROSCI.4699-06.2007  0.6
2006 von der Brelie C, Waltereit R, Zhang L, Beck H, Kirschstein T. Impaired synaptic plasticity in a rat model of tuberous sclerosis. The European Journal of Neuroscience. 23: 686-92. PMID 16487150 DOI: 10.1111/j.1460-9568.2006.04594.x  0.6
2005 Zhang L, Kirschstein T, Sommersberg B, Merkens M, Manahan-Vaughan D, Elgersma Y, Beck H. Hippocampal synaptic metaplasticity requires inhibitory autophosphorylation of Ca2+/calmodulin-dependent kinase II. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7697-707. PMID 16107656 DOI: 10.1523/JNEUROSCI.2086-05.2005  0.6
2004 Kirschstein T, von der Brelie C, Steinhäuser M, Vinçon A, Beck H, Dietrich D. L-CCG-I activates group III metabotropic glutamate receptors in the hippocampal CA3 region. Neuropharmacology. 47: 157-62. PMID 15223294 DOI: 10.1016/j.neuropharm.2004.04.004  0.6
2003 Dietrich D, Kirschstein T, Kukley M, Pereverzev A, von der Brelie C, Schneider T, Beck H. Functional specialization of presynaptic Cav2.3 Ca2+ channels. Neuron. 39: 483-96. PMID 12895422 DOI: 10.1016/S0896-6273(03)00430-6  0.6
2003 Kirschstein T, Fernández G, Grunwald T, Pezer N, Urbach H, Blümcke I, Van Roost D, Lehnertz K, Elger CE. Heterotopias, cortical dysplasias and glioneural tumors participate in cognitive processing in patients with temporal lobe epilepsy. Neuroscience Letters. 338: 237-41. PMID 12581840 DOI: 10.1016/S0304-3940(02)01398-8  0.6
2002 Greffrath W, Kirschstein T, Nawrath H, Treede RD. Acetylsalicylic acid reduces heat responses in rat nociceptive primary sensory neurons--evidence for a new mechanism of action. Neuroscience Letters. 320: 61-4. PMID 11849764 DOI: 10.1016/S0304-3940(02)00033-2  0.6
2001 Greffrath W, Kirschstein T, Nawrath H, Treede RD. Changes in cytosolic calcium in response to noxious heat and their relationship to vanilloid receptors in rat dorsal root ganglion neurons Neuroscience. 104: 539-550. PMID 11377853 DOI: 10.1016/S0306-4522(01)00088-4  0.6
1999 Kirschstein T, Greffrath W, Büsselberg D, Treede RD. Inhibition of rapid heat responses in nociceptive primary sensory neurons of rats by vanilloid receptor antagonists Journal of Neurophysiology. 82: 2853-2860. PMID 10601424  0.6
1997 Kirschstein T, Büsselberg D, Treede RD. Coexpression of heat-evoked and capsaicin-evoked inward currents in acutely dissociated rat dorsal root ganglion neurons Neuroscience Letters. 231: 33-36. PMID 9280161 DOI: 10.1016/S0304-3940(97)00533-8  0.6
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