Vanessa N. Barth, Ph.D. - Publications

Affiliations: 
2006 Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Neuroscience Biology, Pharmacology

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Gardinier KM, Gernert DL, Porter WJ, Reel JK, Ornstein PL, Spinazze P, Stevens FC, Hahn P, Hollinshead SP, Mayhugh D, Schkeryantz J, Khilevich A, De Frutos O, Gleason SD, Kato AS, ... ... Barth VN, et al. The Discovery of The First α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent Upon Transmembrane AMPA Receptor Regulatory Protein (TARP) Gamma-8. Journal of Medicinal Chemistry. PMID 27067148 DOI: 10.1021/acs.jmedchem.6b00125  0.36
2015 Bakker G, Vingerhoets WA, van Wieringen JP, de Bruin K, Eersels J, de Jong J, Chahid Y, Rutten BP, DuBois S, Watson M, Mogg AJ, Xiao H, Crabtree M, Collier DA, Felder CC, ... Barth VN, et al. 123I-iododexetimide preferentially binds to the muscarinic receptor subtype M1 in vivo. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 56: 317-22. PMID 25593117 DOI: 10.2967/jnumed.114.147488  0.36
2014 Toledo MA, Pedregal C, Lafuente C, Diaz N, Martinez-Grau MA, Jiménez A, Benito A, Torrado A, Mateos C, Joshi EM, Kahl SD, Rash KS, Mudra DR, Barth VN, Shaw DB, et al. Discovery of a novel series of orally active nociceptin/orphanin FQ (NOP) receptor antagonists based on a dihydrospiro(piperidine-4,7'-thieno[2,3-c]pyran) scaffold. Journal of Medicinal Chemistry. 57: 3418-29. PMID 24678969 DOI: 10.1021/jm500117r  0.36
2014 Lohith TG, Zoghbi SS, Morse CL, Araneta MD, Barth VN, Goebl NA, Tauscher JT, Pike VW, Innis RB, Fujita M. Retest imaging of [11C]NOP-1A binding to nociceptin/orphanin FQ peptide (NOP) receptors in the brain of healthy humans. Neuroimage. 87: 89-95. PMID 24225488 DOI: 10.1016/j.neuroimage.2013.10.068  0.36
2013 Zanotti-Fregonara P, Barth VN, Zoghbi SS, Liow JS, Nisenbaum E, Siuda E, Gladding RL, Rallis-Frutos D, Morse C, Tauscher J, Pike VW, Innis RB. 11C-LY2428703, a positron emission tomographic radioligand for the metabotropic glutamate receptor 1, is unsuitable for imaging in monkey and human brains. Ejnmmi Research. 3: 47. PMID 23758896 DOI: 10.1186/2191-219X-3-47  0.36
2013 Zanotti-Fregonara P, Barth VN, Liow JS, Zoghbi SS, Clark DT, Rhoads E, Siuda E, Heinz BA, Nisenbaum E, Dressman B, Joshi E, Luffer-Atlas D, Fisher MJ, Masters JJ, Goebl N, et al. Evaluation in vitro and in animals of a new 11C-labeled PET radioligand for metabotropic glutamate receptors 1 in brain. European Journal of Nuclear Medicine and Molecular Imaging. 40: 245-53. PMID 23135321 DOI: 10.1007/s00259-012-2269-7  0.36
2012 Pedregal C, Joshi EM, Toledo MA, Lafuente C, Diaz N, Martinez-Grau MA, Jiménez A, Benito A, Navarro A, Chen Z, Mudra DR, Kahl SD, Rash KS, Statnick MA, Barth VN. Development of LC-MS/MS-based receptor occupancy tracers and positron emission tomography radioligands for the nociceptin/orphanin FQ (NOP) receptor. Journal of Medicinal Chemistry. 55: 4955-67. PMID 22541041 DOI: 10.1021/jm201629q  0.36
2012 Fisher MJ, Backer RT, Barth VN, Garbison KE, Gruber JM, Heinz BA, Iyengar S, Hollinshead SP, Kingston A, Kuklish SL, Li L, Nisenbaum ES, Peters SC, Phebus L, Simmons RM, et al. 3-Phenyl-5-isothiazole carboxamides with potent mGluR1 antagonist activity. Bioorganic & Medicinal Chemistry Letters. 22: 2514-7. PMID 22386665 DOI: 10.1016/j.bmcl.2012.02.003  0.36
2012 Lohith TG, Zoghbi SS, Morse CL, Araneta MF, Barth VN, Goebl NA, Tauscher JT, Pike VW, Innis RB, Fujita M. Brain and whole-body imaging of nociceptin/orphanin FQ peptide receptor in humans using the PET ligand 11C-NOP-1A. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 385-92. PMID 22312136 DOI: 10.2967/jnumed.111.097162  0.36
2012 Barth VN, Joshi EM, Silva MD. Target Engagement for PK/PD Modeling and Translational Imaging Biomarkers Adme-Enabling Technologies in Drug Design and Development. 493-511. DOI: 10.1002/9781118180778.ch33  0.36
2011 Mitch CH, Quimby SJ, Diaz N, Pedregal C, de la Torre MG, Jimenez A, Shi Q, Canada EJ, Kahl SD, Statnick MA, McKinzie DL, Benesh DR, Rash KS, Barth VN. Discovery of aminobenzyloxyarylamides as κ opioid receptor selective antagonists: application to preclinical development of a κ opioid receptor antagonist receptor occupancy tracer. Journal of Medicinal Chemistry. 54: 8000-12. PMID 21958337 DOI: 10.1021/jm200789r  0.36
2011 Kimura Y, Fujita M, Hong J, Lohith TG, Gladding RL, Zoghbi SS, Tauscher JA, Goebl N, Rash KS, Chen Z, Pedregal C, Barth VN, Pike VW, Innis RB. Brain and whole-body imaging in rhesus monkeys of 11C-NOP-1A, a promising PET radioligand for nociceptin/orphanin FQ peptide receptors. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 52: 1638-45. PMID 21880575 DOI: 10.2967/jnumed.111.091181  0.36
2011 Pike VW, Rash KS, Chen Z, Pedregal C, Statnick MA, Kimura Y, Hong J, Zoghbi SS, Fujita M, Toledo MA, Diaz N, Gackenheimer SL, Tauscher JT, Barth VN, Innis RB. Synthesis and evaluation of radioligands for imaging brain nociceptin/orphanin FQ peptide (NOP) receptors with positron emission tomography. Journal of Medicinal Chemistry. 54: 2687-700. PMID 21438532 DOI: 10.1021/jm101487v  0.36
2009 Fell MJ, Perry KW, Falcone JF, Johnson BG, Barth VN, Rash KS, Lucaites VL, Threlkeld PG, Monn JA, McKinzie DL, Marek GJ, Svensson KA, Nelson DL. In vitro and in vivo evidence for a lack of interaction with dopamine D2 receptors by the metabotropic glutamate 2/3 receptor agonists 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-bicaroxylate monohydrate (LY354740) and (-)-2-oxa-4-aminobicyclo[3.1.0] Hexane-4,6-dicarboxylic acid (LY379268). The Journal of Pharmacology and Experimental Therapeutics. 331: 1126-36. PMID 19755662 DOI: 10.1124/jpet.109.160598  0.36
2006 Barth VN, Chernet E, Martin LJ, Need AB, Rash KS, Morin M, Phebus LA. Comparison of rat dopamine D2 receptor occupancy for a series of antipsychotic drugs measured using radiolabeled or nonlabeled raclopride tracer. Life Sciences. 78: 3007-12. PMID 16434058 DOI: 10.1016/j.lfs.2005.11.031  0.36
2005 Chernet E, Martin LJ, Li D, Need AB, Barth VN, Rash KS, Phebus LA. Use of LC/MS to assess brain tracer distribution in preclinical, in vivo receptor occupancy studies: dopamine D2, serotonin 2A and NK-1 receptors as examples. Life Sciences. 78: 340-6. PMID 16139310 DOI: 10.1016/j.lfs.2005.04.075  0.36
2005 Seager MA, Barth VN, Phebus LA, Rasmussen K. Chronic coadministration of olanzapine and fluoxetine activates locus coeruleus neurons in rats: implications for bipolar disorder. Psychopharmacology. 181: 126-33. PMID 15719213 DOI: 10.1007/s00213-005-2198-2  0.36
2004 Seager MA, Huff KD, Barth VN, Phebus LA, Rasmussen K. Fluoxetine administration potentiates the effect of olanzapine on locus coeruleus neuronal activity. Biological Psychiatry. 55: 1103-9. PMID 15158430 DOI: 10.1016/j.biopsych.2004.02.012  0.36
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