| Year |
Citation |
Score |
| 2019 |
Knopp KL, Simmons RMA, Guo W, Adams BL, Gardinier KM, Gernert DL, Ornstein PL, Porter W, Reel J, Ding C, Wang H, Qian Y, Burris KD, Need A, Barth V, et al. Modulation of TARP γ8-containing AMPA Receptors as a Novel Therapeutic Approach for Chronic Pain. The Journal of Pharmacology and Experimental Therapeutics. PMID 30910921 DOI: 10.1124/Jpet.118.250126 |
0.619 |
|
| 2016 |
Gardinier KM, Gernert DL, Porter WJ, Reel JK, Ornstein PL, Spinazze P, Stevens FC, Hahn P, Hollinshead SP, Mayhugh D, Schkeryantz J, Khilevich A, De Frutos O, Gleason SD, Kato AS, ... ... Need AB, et al. The Discovery of The First α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent Upon Transmembrane AMPA Receptor Regulatory Protein (TARP) Gamma-8. Journal of Medicinal Chemistry. PMID 27067148 DOI: 10.1021/Acs.Jmedchem.6B00125 |
0.648 |
|
| 2014 |
Rorick-Kehn LM, Witcher JW, Lowe SL, Gonzales CR, Weller MA, Bell RL, Hart JC, Need AB, McKinzie JH, Statnick MA, Suico JG, McKinzie DL, Tauscher-Wisniewski S, Mitch CH, Stoltz RR, et al. Determining pharmacological selectivity of the kappa opioid receptor antagonist LY2456302 using pupillometry as a translational biomarker in rat and human. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25637376 DOI: 10.1093/ijnp/pyu036 |
0.308 |
|
| 2014 |
Joshi EM, Need A, Schaus J, Chen Z, Benesh D, Mitch C, Morton S, Raub TJ, Phebus L, Barth V. Efficiency gains in tracer identification for nuclear imaging: can in vivo LC-MS/MS evaluation of small molecules screen for successful PET tracers? Acs Chemical Neuroscience. 5: 1154-63. PMID 25247893 DOI: 10.1021/cn500073j |
0.634 |
|
| 2014 |
Zheng MQ, Kim SJ, Holden D, Lin SF, Need A, Rash K, Barth V, Mitch C, Navarro A, Kapinos M, Maloney K, Ropchan J, Carson RE, Huang Y. An Improved Antagonist Radiotracer for the κ-Opioid Receptor: Synthesis and Characterization of (11)C-LY2459989. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 55: 1185-91. PMID 24854795 DOI: 10.2967/jnumed.114.138701 |
0.622 |
|
| 2014 |
Barth V, Need A. Identifying novel radiotracers for PET imaging of the brain: application of LC-MS/MS to tracer identification. Acs Chemical Neuroscience. 5: 1148-53. PMID 24828747 DOI: 10.1021/cn500072r |
0.616 |
|
| 2007 |
Need AB, McKinzie JH, Mitch CH, Statnick MA, Phebus LA. In vivo rat brain opioid receptor binding of LY255582 assessed with a novel method using LC/MS/MS and the administration of three tracers simultaneously. Life Sciences. 81: 1389-96. PMID 17935738 DOI: 10.1016/j.lfs.2007.09.005 |
0.351 |
|
| 2006 |
Li X, Need AB, Baez M, Witkin JM. Metabotropic glutamate 5 receptor antagonism is associated with antidepressant-like effects in mice. The Journal of Pharmacology and Experimental Therapeutics. 319: 254-9. PMID 16803860 DOI: 10.1124/jpet.106.103143 |
0.341 |
|
| 2006 |
Barth VN, Chernet E, Martin LJ, Need AB, Rash KS, Morin M, Phebus LA. Comparison of rat dopamine D2 receptor occupancy for a series of antipsychotic drugs measured using radiolabeled or nonlabeled raclopride tracer. Life Sciences. 78: 3007-12. PMID 16434058 DOI: 10.1016/j.lfs.2005.11.031 |
0.661 |
|
| 2006 |
Need AB, Davis RJ, Alexander-Chacko JT, Eastwood B, Chernet E, Phebus LA, Sindelar DK, Nomikos GG. The relationship of in vivo central CB1 receptor occupancy to changes in cortical monoamine release and feeding elicited by CB1 receptor antagonists in rats. Psychopharmacology. 184: 26-35. PMID 16328376 DOI: 10.1007/s00213-005-0234-x |
0.337 |
|
| 2005 |
Chernet E, Martin LJ, Li D, Need AB, Barth VN, Rash KS, Phebus LA. Use of LC/MS to assess brain tracer distribution in preclinical, in vivo receptor occupancy studies: dopamine D2, serotonin 2A and NK-1 receptors as examples. Life Sciences. 78: 340-6. PMID 16139310 DOI: 10.1016/j.lfs.2005.04.075 |
0.67 |
|
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