| Year |
Citation |
Score |
| 2024 |
Chandler CM, Nickell JR, George Wilson A, Culver JP, Crooks PA, Bardo MT, Dwoskin LP. Vesicular monoamine transporter-2 inhibitor JPC-141 prevents methamphetamine-induced dopamine toxicity and blocks methamphetamine self-administration in rats. Biochemical Pharmacology. 116189. PMID 38580165 DOI: 10.1016/j.bcp.2024.116189 |
0.378 |
|
| 2022 |
Thompson BM, Tracy ME, Huynh YW, Dwoskin LP, Barrett ST, Bevins RA. Varenicline serves as the training stimulus in the drug-discriminated goal-tracking task with rats: initial evaluation of potential neuropharmacological processes. Behavioural Pharmacology. 34: 12-19. PMID 36730812 DOI: 10.1097/FBP.0000000000000707 |
0.311 |
|
| 2019 |
Lee NR, Zheng G, Leggas M, Janganati V, Nickell JR, Crooks PA, Bardo MT, Dwoskin L. GZ-11608, a Vesicular Monoamine Transporter-2 Inhibitor, Decreases the Neurochemical and Behavioral Effects of Methamphetamine. The Journal of Pharmacology and Experimental Therapeutics. PMID 31413138 DOI: 10.1124/Jpet.119.258699 |
0.493 |
|
| 2019 |
Bardo MT, Denehy ED, Hammerslag LR, Dwoskin LP, Blough BE, Landavazo A, Bergman J, Kohut SJ. Effects of methamphetamine isomers on d-methamphetamine self-administration and food-maintained responding in male rats. Psychopharmacology. PMID 31346628 DOI: 10.1007/S00213-019-05327-8 |
0.331 |
|
| 2018 |
Lee NR, Gujarathi S, Bommagani S, Siripurapu K, Zheng G, Dwoskin LP. Muscarinic agonist, (±)-quinuclidin-3-yl-(4-fluorophenethyl)(phenyl)carbamate: High affinity, but low subtype selectivity for human M - M muscarinic acetylcholine receptors. Bioorganic & Medicinal Chemistry Letters. PMID 30554957 DOI: 10.1016/J.Bmcl.2018.12.022 |
0.379 |
|
| 2018 |
Maggio SE, Saunders MA, Nixon K, Prendergast MA, Zheng G, Crooks PA, Dwoskin LP, Bell RL, Bardo MT. An improved model of ethanol and nicotine co-use in female P rats: Effects of naltrexone, varenicline, and the selective nicotinic α6β2* antagonist r-bPiDI. Drug and Alcohol Dependence. 193: 154-161. PMID 30384323 DOI: 10.1016/J.Drugalcdep.2018.09.008 |
0.617 |
|
| 2018 |
Maggio SE, Saunders MA, Baxter TA, Nixon K, Prendergast MA, Zheng G, Crooks P, Dwoskin LP, Slack RD, Newman AH, Bell RL, Bardo MT. Effects of the nicotinic agonist varenicline, nicotinic antagonist r-bPiDI, and DAT inhibitor (R)-modafinil on co-use of ethanol and nicotine in female P rats. Psychopharmacology. PMID 29455292 DOI: 10.1007/S00213-018-4853-4 |
0.604 |
|
| 2018 |
Lee NR, Zheng G, Crooks PA, Bardo MT, Dwoskin LP. New Scaffold for Lead Compounds to Treat Methamphetamine Use Disorders. The Aaps Journal. 20: 29. PMID 29427069 DOI: 10.1208/S12248-018-0192-Y |
0.485 |
|
| 2017 |
Hankosky ER, Joolakanti SR, Nickell JR, Janganati V, Dwoskin LP, Crooks PA. Fluoroethoxy-1,4-diphenethylpiperidine and piperazine derivatives: Potent and selective inhibitors of [(3)H]dopamine uptake at the vesicular monoamine transporter-2. Bioorganic & Medicinal Chemistry Letters. PMID 29153425 DOI: 10.1016/J.Bmcl.2017.10.039 |
0.416 |
|
| 2017 |
Kangiser MM, Dwoskin LP, Zheng G, Crooks PA, Stairs DJ. Varenicline and GZ-793A differentially decrease methamphetamine self-administration under a multiple schedule of reinforcement in rats. Behavioural Pharmacology. PMID 28863003 DOI: 10.1097/Fbp.0000000000000340 |
0.374 |
|
| 2017 |
Marusich JA, Darna M, Wilson AG, Denehy ED, Ebben A, Deaciuc AG, Dwoskin LP, Bardo MT, Lefever TW, Wiley JL, Reissig CJ, Jackson KJ. Tobacco's minor alkaloids: effects on place conditioning and nucleus accumbens dopamine release in adult and adolescent rats. European Journal of Pharmacology. PMID 28844873 DOI: 10.1016/J.Ejphar.2017.08.029 |
0.474 |
|
| 2017 |
Baskin BM, Nic Dhonnchadha BÁ, Dwoskin LP, Kantak KM. Blockade of α2-adrenergic receptors in prelimbic cortex: impact on cocaine self-administration in adult spontaneously hypertensive rats following adolescent atomoxetine treatment. Psychopharmacology. PMID 28730282 DOI: 10.1007/S00213-017-4681-Y |
0.37 |
|
| 2017 |
Wilson AG, Lee N, Nickell JR, Culver JP, Janganati V, Zheng G, Crooks PA, Dwoskin LP, Bardo MT. Oral JPC-077, a vesicular monoamine transporter-2 inhibitor, reduces methamphetamine self-administration across repeated treatments Drug and Alcohol Dependence. 171: e218. DOI: 10.1016/J.Drugalcdep.2016.08.595 |
0.329 |
|
| 2016 |
Fox-Loe AM, Dwoskin LP, Richards CI. Nicotinic Acetylcholine Receptors as Targets for Tobacco Cessation Therapeutics: Cutting-Edge Methodologies to Understand Receptor Assembly and Trafficking. Neuromethods. 117: 119-132. PMID 28025590 DOI: 10.1007/978-1-4939-3768-4_7 |
0.318 |
|
| 2016 |
Nickell JR, Siripurapu KB, Horton DB, Zheng G, Crooks PA, Dwoskin LP. GZ-793A inhibits the neurochemical effects of methamphetamine via a selective interaction with the vesicular monoamine transporter-2. European Journal of Pharmacology. 795: 143-149. PMID 27986625 DOI: 10.1016/J.Ejphar.2016.12.016 |
0.748 |
|
| 2016 |
Narayanaswami V, Dwoskin LP. Obesity: Current and Potential Pharmacotherapeutics and Targets. Pharmacology & Therapeutics. PMID 27773782 DOI: 10.1016/J.Pharmthera.2016.10.015 |
0.601 |
|
| 2016 |
Charntikov S, Falco AM, Fink K, Dwoskin LP, Bevins RA. The effect of Sazetidine-A and other nicotinic ligands on nicotine controlled goal-tracking in female and male rats. Neuropharmacology. PMID 27765626 DOI: 10.1016/J.Neuropharm.2016.10.014 |
0.389 |
|
| 2016 |
Jordan CJ, Lemay C, Dwoskin LP, Kantak KM. Adolescent d-amphetamine treatment in a rodent model of attention deficit/hyperactivity disorder: impact on cocaine abuse vulnerability in adulthood. Psychopharmacology. PMID 27600990 DOI: 10.1007/S00213-016-4419-2 |
0.369 |
|
| 2016 |
Nickell JR, Culver JP, Janganati V, Zheng G, Dwoskin LP, Crooks PA. Synthesis and in vitro evaluation of water-soluble 1,4-diphenethylpiperazine analogs as novel inhibitors of the vesicular monoamine transporter-2. Bioorganic & Medicinal Chemistry Letters. PMID 27524311 DOI: 10.1016/J.Bmcl.2016.08.001 |
0.388 |
|
| 2016 |
Nickell JR, Culver JP, Janganati V, Zheng G, Dwoskin LP, Crooks PA. 1,4-Diphenalkylpiperidines: A new scaffold for the design of potent inhibitors of the vesicular monoamine transporter-2. Bioorganic & Medicinal Chemistry Letters. PMID 27212067 DOI: 10.1016/J.Bmcl.2016.05.025 |
0.427 |
|
| 2016 |
Joolakanti SR, Nickell JR, Janganati V, Zheng G, Dwoskin LP, Crooks PA. Lobelane analogues containing 4-hydroxy and 4-(2-fluoroethoxy) aromatic substituents: Potent and selective inhibitors of [(3)H]dopamine uptake at the vesicular monoamine transporter-2. Bioorganic & Medicinal Chemistry Letters. PMID 27080180 DOI: 10.1016/J.Bmcl.2016.03.119 |
0.431 |
|
| 2015 |
Somkuwar SS, Kantak KM, Bardo MT, Dwoskin LP. Adolescent methylphenidate treatment differentially alters adult impulsivity and hyperactivity in the Spontaneously Hypertensive Rat model of ADHD. Pharmacology, Biochemistry, and Behavior. 141: 66-77. PMID 26657171 DOI: 10.1016/J.Pbb.2015.12.002 |
0.746 |
|
| 2015 |
Yates JR, Darna M, Beckmann JS, Dwoskin LP, Bardo MT. Individual differences in impulsive action and dopamine transporter function in rat orbitofrontal cortex. Neuroscience. PMID 26608122 DOI: 10.1016/J.Neuroscience.2015.11.033 |
0.376 |
|
| 2015 |
Van Skike CE, Maggio SE, Reynolds AR, Casey EM, Bardo MT, Dwoskin LP, Prendergast MA, Nixon K. Critical needs in drug discovery for cessation of alcohol and nicotine polysubstance abuse. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 26582145 DOI: 10.1016/J.Pnpbp.2015.11.004 |
0.558 |
|
| 2015 |
Lee NR, Zhang X, Darna M, Dwoskin LP, Zheng G. Muscarinic acetylcholine receptor binding affinities of pethidine analogs. Bioorganic & Medicinal Chemistry Letters. PMID 26494260 DOI: 10.1016/J.Bmcl.2015.10.029 |
0.315 |
|
| 2015 |
Jordan CJ, Taylor DM, Dwoskin LP, Kantak KM. Adolescent d-amphetamine treatment in a rodent model of ADHD: Pro-cognitive effects in adolescence without an impact on cocaine cue reactivity in adulthood. Behavioural Brain Research. 297: 165-179. PMID 26467602 DOI: 10.1016/J.Bbr.2015.10.017 |
0.361 |
|
| 2015 |
Pittenger ST, Zeplin LC, Dwoskin LP, Bevins RA. The effect of switching pharmacological intervention during extinction on nicotine-evoked conditioned responding in rats. Psychopharmacology. 232: 4347-58. PMID 26364957 DOI: 10.1007/S00213-015-4067-Y |
0.34 |
|
| 2015 |
Beckmann JS, Meyer AC, Pivavarchyk M, Horton DB, Zheng G, Smith AM, Wooters TE, McIntosh JM, Crooks PA, Bardo MT, Dwoskin LP. r-bPiDI, an α6β2* Nicotinic Receptor Antagonist, Decreases Nicotine-Evoked Dopamine Release and Nicotine Reinforcement. Neurochemical Research. PMID 26227997 DOI: 10.1007/S11064-015-1680-4 |
0.771 |
|
| 2015 |
Darna M, Chow JJ, Yates JR, Charnigo RJ, Beckmann JS, Bardo MT, Dwoskin LP. Role of serotonin transporter function in rat orbitofrontal cortex in impulsive choice. Behavioural Brain Research. 293: 134-142. PMID 26183652 DOI: 10.1016/J.Bbr.2015.07.025 |
0.332 |
|
| 2015 |
Yates JR, Darna M, Gipson CD, Dwoskin LP, Bardo MT. Dissociable roles of dopamine and serotonin transporter function in a rat model of negative urgency. Behavioural Brain Research. 291: 201-208. PMID 26005123 DOI: 10.1016/J.Bbr.2015.05.023 |
0.405 |
|
| 2015 |
Ding D, Nickell JR, Dwoskin LP, Crooks PA. Quinolyl analogues of norlobelane: Novel potent inhibitors of [(3)H]dihydrotetrabenazine binding and [(3)H]dopamine uptake at the vesicular monoamine transporter-2. Bioorganic & Medicinal Chemistry Letters. 25: 2613-6. PMID 25991431 DOI: 10.1016/J.Bmcl.2015.04.105 |
0.416 |
|
| 2015 |
Holt JC, Kewin K, Jordan PM, Cameron P, Klapczynski M, McIntosh JM, Crooks PA, Dwoskin LP, Lysakowski A. Pharmacologically distinct nicotinic acetylcholine receptors drive efferent-mediated excitation in calyx-bearing vestibular afferents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 3625-43. PMID 25716861 DOI: 10.1523/Jneurosci.3388-14.2015 |
0.331 |
|
| 2015 |
Somkuwar SS, Kantak KM, Dwoskin LP. Effect of methylphenidate treatment during adolescence on norepinephrine transporter function in orbitofrontal cortex in a rat model of attention deficit hyperactivity disorder. Journal of Neuroscience Methods. PMID 25680322 DOI: 10.1016/J.Jneumeth.2015.02.002 |
0.738 |
|
| 2015 |
Baskin BM, Dwoskin LP, Kantak KM. Methylphenidate treatment beyond adolescence maintains increased cocaine self-administration in the spontaneously hypertensive rat model of attention deficit/hyperactivity disorder. Pharmacology, Biochemistry, and Behavior. 131: 51-6. PMID 25643872 DOI: 10.1016/J.Pbb.2015.01.019 |
0.354 |
|
| 2015 |
Darna M, Beckmann JS, Gipson CD, Bardo MT, Dwoskin LP. Effect of environmental enrichment on dopamine and serotonin transporters and glutamate neurotransmission in medial prefrontal and orbitofrontal cortex. Brain Research. 1599: 115-25. PMID 25536304 DOI: 10.1016/J.Brainres.2014.12.034 |
0.429 |
|
| 2015 |
Wilson AG, Nickell J, Culver JP, Janganati V, Zheng G, Crooks PA, Dwoskin LP, Bardo MT. Oral JPC-077 and JPC-141, vesicular monoamine transporter-2 inhibitors, reduce methamphetamine self-administration and methamphetamine-induced reinstatement in rats Drug and Alcohol Dependence. 156: e239. DOI: 10.1016/J.Drugalcdep.2015.07.644 |
0.36 |
|
| 2015 |
Jordan CJ, Taylor DM, Jeon S, Baskin BM, Dwoskin LP, Kantak KM. Adolescent d -amphetamine treatment in a rodent model of ADHD: Pro-cognitive effects during adolescence and cocaine abuse risk during adulthood Drug and Alcohol Dependence. 156: e105. DOI: 10.1016/J.Drugalcdep.2015.07.291 |
0.324 |
|
| 2015 |
Somkuwar SS, Kantak K, Dwoskin LP. Decreased norepinephrine transporter function in the orbitofrontal cortex and enhanced cocaine abuse risk following adolescent methylphenidate treatment in a rat model of Attention Deficit Hyperactivity Disorder Drug and Alcohol Dependence. 146: e103. DOI: 10.1016/J.Drugalcdep.2014.09.648 |
0.743 |
|
| 2015 |
Jordan CJ, Harvey RC, Baskin BM, Rodriguez K, Dellamorte A, Dwoskin LP, Kantak KM. Adolescent atomoxetine, but not methylphenidate, decreases cocaine-seeking behavior in a genetic model of attention-deficit/hyperactivity disorder Drug and Alcohol Dependence. 146: e151. DOI: 10.1016/J.Drugalcdep.2014.09.327 |
0.319 |
|
| 2014 |
De Biasi M, McLaughlin I, Perez EE, Crooks PA, Dwoskin LP, Bardo MT, Pentel PR, Hatsukami D. Scientific overview: 2013 BBC plenary symposium on tobacco addiction. Drug and Alcohol Dependence. 141: 107-17. PMID 24934691 DOI: 10.1016/J.Drugalcdep.2014.05.013 |
0.314 |
|
| 2014 |
Hofford RS, Darna M, Wilmouth CE, Dwoskin LP, Bardo MT. Environmental enrichment reduces methamphetamine cue-induced reinstatement but does not alter methamphetamine reward or VMAT2 function. Behavioural Brain Research. 270: 151-8. PMID 24821405 DOI: 10.1016/J.Bbr.2014.05.007 |
0.378 |
|
| 2014 |
Jordan CJ, Harvey RC, Baskin BB, Dwoskin LP, Kantak KM. Cocaine-seeking behavior in a genetic model of attention-deficit/hyperactivity disorder following adolescent methylphenidate or atomoxetine treatments. Drug and Alcohol Dependence. 140: 25-32. PMID 24811203 DOI: 10.1016/J.Drugalcdep.2014.04.020 |
0.352 |
|
| 2014 |
Gauthier JM, Tassin DH, Dwoskin LP, Kantak KM. Effects of dopamine D1 receptor blockade in the prelimbic prefrontal cortex or lateral dorsal striatum on frontostriatal function in Wistar and Spontaneously Hypertensive Rats. Behavioural Brain Research. 268: 229-38. PMID 24755309 DOI: 10.1016/J.Bbr.2014.04.018 |
0.404 |
|
| 2014 |
Crooks PA, Bardo MT, Dwoskin LP. Nicotinic receptor antagonists as treatments for nicotine abuse. Advances in Pharmacology (San Diego, Calif.). 69: 513-51. PMID 24484986 DOI: 10.1016/B978-0-12-420118-7.00013-5 |
0.502 |
|
| 2014 |
Nickell JR, Siripurapu KB, Vartak A, Crooks PA, Dwoskin LP. The vesicular monoamine transporter-2: an important pharmacological target for the discovery of novel therapeutics to treat methamphetamine abuse. Advances in Pharmacology (San Diego, Calif.). 69: 71-106. PMID 24484975 DOI: 10.1016/B978-0-12-420118-7.00002-0 |
0.513 |
|
| 2014 |
Nickell JR, Beckmann J, Denehy E, Siripurapu K, Culver J, Bardo M, Crooks P, Dwoskin LP. Preclinical evaluation of JPC-077 as a novel treatment for methamphetamine abuse Drug and Alcohol Dependence. 140: e160-e161. DOI: 10.1016/J.Drugalcdep.2014.02.453 |
0.387 |
|
| 2014 |
Darna M, Yates JR, Bardo M, Dwoskin LP. Individual differences in negative urgency behavior: Relationship with dopamine transporter function Drug and Alcohol Dependence. 140: e43. DOI: 10.1016/J.Drugalcdep.2014.02.139 |
0.354 |
|
| 2013 |
Wilmouth CE, Zheng G, Crooks PA, Dwoskin LP, Bardo MT. Oral administration of GZ-793A, a VMAT2 inhibitor, decreases methamphetamine self-administration in rats. Pharmacology, Biochemistry, and Behavior. 112: 29-33. PMID 24075974 DOI: 10.1016/J.Pbb.2013.09.006 |
0.327 |
|
| 2013 |
Ding D, Nickell JR, Deaciuc AG, Penthala NR, Dwoskin LP, Crooks PA. Synthesis and evaluation of novel azetidine analogs as potent inhibitors of vesicular [3H]dopamine uptake. Bioorganic & Medicinal Chemistry. 21: 6771-7. PMID 23993667 DOI: 10.1016/J.Bmc.2013.08.001 |
0.355 |
|
| 2013 |
Martin CA, Nuzzo PA, Ranseen JD, Kleven MS, Guenthner G, Williams Y, Walsh SL, Dwoskin LP. Lobeline Effects on Cognitive Performance in Adult ADHD. Journal of Attention Disorders. PMID 23966351 DOI: 10.1177/1087054713497791 |
0.767 |
|
| 2013 |
Meyer AC, Neugebauer NM, Zheng G, Crooks PA, Dwoskin LP, Bardo MT. Effects of VMAT2 inhibitors lobeline and GZ-793A on methamphetamine-induced changes in dopamine release, metabolism and synthesis in vivo. Journal of Neurochemistry. 127: 187-98. PMID 23875705 DOI: 10.1111/Jnc.12373 |
0.411 |
|
| 2013 |
Horton DB, Nickell JR, Zheng G, Crooks PA, Dwoskin LP. GZ-793A, a lobelane analog, interacts with the vesicular monoamine transporter-2 to inhibit the effect of methamphetamine. Journal of Neurochemistry. 127: 177-86. PMID 23875622 DOI: 10.1111/Jnc.12371 |
0.742 |
|
| 2013 |
Narayanaswami V, Somkuwar SS, Horton DB, Cassis LA, Dwoskin LP. Angiotensin AT1 and AT2 receptor antagonists modulate nicotine-evoked [³H]dopamine and [³H]norepinephrine release. Biochemical Pharmacology. 86: 656-65. PMID 23831951 DOI: 10.1016/J.Bcp.2013.06.025 |
0.821 |
|
| 2013 |
Somkuwar SS, Jordan CJ, Kantak KM, Dwoskin LP. Adolescent atomoxetine treatment in a rodent model of ADHD: effects on cocaine self-administration and dopamine transporters in frontostriatal regions. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2588-97. PMID 23822950 DOI: 10.1038/Npp.2013.163 |
0.753 |
|
| 2013 |
Somkuwar SS, Darna M, Kantak KM, Dwoskin LP. Adolescence methylphenidate treatment in a rodent model of attention deficit/hyperactivity disorder: dopamine transporter function and cellular distribution in adulthood. Biochemical Pharmacology. 86: 309-16. PMID 23623751 DOI: 10.1016/J.Bcp.2013.04.013 |
0.759 |
|
| 2013 |
Nickell JR, Grinevich VP, Siripurapu KB, Smith AM, Dwoskin LP. Potential therapeutic uses of mecamylamine and its stereoisomers. Pharmacology, Biochemistry, and Behavior. 108: 28-43. PMID 23603417 DOI: 10.1016/J.Pbb.2013.04.005 |
0.409 |
|
| 2013 |
Penthala NR, Ponugoti PR, Nickell JR, Deaciuc AG, Dwoskin LP, Crooks PA. Pyrrolidine analogs of GZ-793A: synthesis and evaluation as inhibitors of the vesicular monoamine transporter-2 (VMAT2). Bioorganic & Medicinal Chemistry Letters. 23: 3342-5. PMID 23597792 DOI: 10.1016/J.Bmcl.2013.03.092 |
0.371 |
|
| 2013 |
Zheng G, Horton DB, Penthala NR, Nickell JR, Culver JP, Deaciuc AG, Dwoskin LP, Crooks PA. Exploring the effect of N-substitution in nor-lobelane on the interaction with VMAT2: discovery of a potential clinical candidate for treatment of methamphetamine abuse. Medchemcomm. 4: 564-568. PMID 23527317 DOI: 10.1039/C3Md20374C |
0.735 |
|
| 2013 |
Zheng G, Smith AM, Huang X, Subramanian KL, Siripurapu KB, Deaciuc A, Zhan CG, Dwoskin LP. Structural modifications to tetrahydropyridine-3-carboxylate esters en route to the discovery of M5-preferring muscarinic receptor orthosteric antagonists. Journal of Medicinal Chemistry. 56: 1693-703. PMID 23379472 DOI: 10.1021/Jm301774U |
0.352 |
|
| 2013 |
Narayanaswami V, Thompson AC, Cassis LA, Bardo MT, Dwoskin LP. Diet-induced obesity: dopamine transporter function, impulsivity and motivation. International Journal of Obesity (2005). 37: 1095-103. PMID 23164701 DOI: 10.1038/Ijo.2012.178 |
0.696 |
|
| 2013 |
Zhu J, Bardo MT, Dwoskin LP. Distinct effects of enriched environment on dopamine clearance in nucleus accumbens shell and core following systemic nicotine administration. Synapse (New York, N.Y.). 67: 57-67. PMID 23065942 DOI: 10.1002/Syn.21615 |
0.545 |
|
| 2013 |
Dwoskin LP, Somkuwar SS, Jordan C, Harvey R, Bardo M, Kantak K. C.10 - METHYLPHENIDATE AND ATOMOXETINE TREATMENT IN THE SPONTANEOUSLY HYPERTENSIVE RAT MODEL OF ATTENTION DEFICIT/HYPERACTIVITY DISORDER Behavioural Pharmacology. 24: e33. DOI: 10.1097/01.Fbp.0000434794.64301.8F |
0.72 |
|
| 2012 |
Alvers KM, Beckmann JS, Zheng G, Crooks PA, Dwoskin LP, Bardo MT. The effect of VMAT2 inhibitor GZ-793A on the reinstatement of methamphetamine-seeking in rats. Psychopharmacology. 224: 255-62. PMID 22638813 DOI: 10.1007/S00213-012-2748-3 |
0.314 |
|
| 2012 |
Yates JR, Darna M, Gipson CD, Dwoskin LP, Bardo MT. Isolation rearing as a preclinical model of attention/deficit-hyperactivity disorder. Behavioural Brain Research. 234: 292-8. PMID 22580232 DOI: 10.1016/J.Bbr.2012.04.043 |
0.4 |
|
| 2012 |
Theodore S, Cass WA, Dwoskin LP, Maragos WF. HIV-1 protein Tat inhibits vesicular monoamine transporter-2 activity in rat striatum. Synapse (New York, N.Y.). 66: 755-7. PMID 22517264 DOI: 10.1002/Syn.21564 |
0.67 |
|
| 2012 |
Smith AM, Wellmann KA, Lundblad TM, Carter ML, Barron S, Dwoskin LP. Lobeline attenuates neonatal ethanol-mediated changes in hyperactivity and dopamine transporter function in the prefrontal cortex in rats. Neuroscience. 206: 245-54. PMID 22119644 DOI: 10.1016/J.Neuroscience.2011.11.018 |
0.364 |
|
| 2012 |
Beckmann JS, Denehy ED, Zheng G, Crooks PA, Dwoskin LP, Bardo MT. The effect of a novel VMAT2 inhibitor, GZ-793A, on methamphetamine reward in rats. Psychopharmacology. 220: 395-403. PMID 21938414 DOI: 10.1007/S00213-011-2488-9 |
0.342 |
|
| 2011 |
Holtman JR, Dwoskin LP, Dowell C, Wala EP, Zhang Z, Crooks PA, McIntosh JM. The novel small molecule α9α10 nicotinic acetylcholine receptor antagonist ZZ-204G is analgesic. European Journal of Pharmacology. 670: 500-8. PMID 21944926 DOI: 10.1016/J.Ejphar.2011.08.053 |
0.382 |
|
| 2011 |
Wooters TE, Dwoskin LP, Bardo MT. Discriminative stimulus effects of NMDA, AMPA, and mGluR5 glutamate receptor ligands in methamphetamine-trained rats. Behavioural Pharmacology. 22: 516-24. PMID 21836462 DOI: 10.1097/Fbp.0B013E328349Aafa |
0.308 |
|
| 2011 |
Horton DB, Siripurapu KB, Zheng G, Crooks PA, Dwoskin LP. Novel N-1,2-dihydroxypropyl analogs of lobelane inhibit vesicular monoamine transporter-2 function and methamphetamine-evoked dopamine release. The Journal of Pharmacology and Experimental Therapeutics. 339: 286-97. PMID 21778282 DOI: 10.1124/Jpet.111.184770 |
0.754 |
|
| 2011 |
Meyer AC, Horton DB, Neugebauer NM, Wooters TE, Nickell JR, Dwoskin LP, Bardo MT. Tetrabenazine inhibition of monoamine uptake and methamphetamine behavioral effects: locomotor activity, drug discrimination and self-administration. Neuropharmacology. 61: 849-56. PMID 21669212 DOI: 10.1016/J.Neuropharm.2011.05.033 |
0.745 |
|
| 2011 |
Marusich JA, Darna M, Charnigo RJ, Dwoskin LP, Bardo MT. A multivariate assessment of individual differences in sensation seeking and impulsivity as predictors of amphetamine self-administration and prefrontal dopamine function in rats. Experimental and Clinical Psychopharmacology. 19: 275-84. PMID 21574722 DOI: 10.1037/A0023897 |
0.348 |
|
| 2011 |
Zheng G, Zhang Z, Dowell C, Wala E, Dwoskin LP, Holtman JR, McIntosh JM, Crooks PA. Discovery of non-peptide, small molecule antagonists of α9α10 nicotinic acetylcholine receptors as novel analgesics for the treatment of neuropathic and tonic inflammatory pain. Bioorganic & Medicinal Chemistry Letters. 21: 2476-9. PMID 21397497 DOI: 10.1016/J.Bmcl.2011.02.043 |
0.387 |
|
| 2011 |
Pivavarchyk M, Smith AM, Zhang Z, Zhou D, Wang X, Toyooka N, Tsuneki H, Sasaoka T, McIntosh JM, Crooks PA, Dwoskin LP. Indolizidine (-)-235B' and related structural analogs: discovery of nicotinic receptor antagonists that inhibit nicotine-evoked [3H]dopamine release. European Journal of Pharmacology. 658: 132-9. PMID 21371454 DOI: 10.1016/J.Ejphar.2011.02.018 |
0.507 |
|
| 2011 |
Wooters TE, Smith AM, Pivavarchyk M, Siripurapu KB, McIntosh JM, Zhang Z, Crooks PA, Bardo MT, Dwoskin LP. bPiDI: a novel selective α6β2* nicotinic receptor antagonist and preclinical candidate treatment for nicotine abuse. British Journal of Pharmacology. 163: 346-57. PMID 21232049 DOI: 10.1111/J.1476-5381.2011.01220.X |
0.534 |
|
| 2011 |
Wooters TE, Bardo MT, Dwoskin LP, Midde NM, Gomez AM, Mactutus CF, Booze RM, Zhu J. Effect of environmental enrichment on methylphenidate-induced locomotion and dopamine transporter dynamics. Behavioural Brain Research. 219: 98-107. PMID 21219939 DOI: 10.1016/J.Bbr.2011.01.001 |
0.808 |
|
| 2011 |
Horton DB, Siripurapu KB, Norrholm SD, Culver JP, Hojahmat M, Beckmann JS, Harrod SB, Deaciuc AG, Bardo MT, Crooks PA, Dwoskin LP. meso-Transdiene analogs inhibit vesicular monoamine transporter-2 function and methamphetamine-evoked dopamine release. The Journal of Pharmacology and Experimental Therapeutics. 336: 940-51. PMID 21177475 DOI: 10.1124/Jpet.110.175117 |
0.824 |
|
| 2011 |
Harvey RC, Sen S, Deaciuc A, Dwoskin LP, Kantak KM. Methylphenidate treatment in adolescent rats with an attention deficit/hyperactivity disorder phenotype: cocaine addiction vulnerability and dopamine transporter function. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 837-47. PMID 21150910 DOI: 10.1038/Npp.2010.223 |
0.434 |
|
| 2011 |
Zhang Z, Zheng G, Pivavarchyk M, Deaciuc AG, Dwoskin LP, Crooks PA. Novel bis-, tris-, and tetrakis-tertiary amino analogs as antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release. Bioorganic & Medicinal Chemistry Letters. 21: 88-91. PMID 21147530 DOI: 10.1016/J.Bmcl.2010.11.070 |
0.52 |
|
| 2011 |
Crooks PA, Zheng G, Vartak AP, Culver JP, Zheng F, Horton DB, Dwoskin LP. Design, synthesis and interaction at the vesicular monoamine transporter-2 of lobeline analogs: potential pharmacotherapies for the treatment of psychostimulant abuse. Current Topics in Medicinal Chemistry. 11: 1103-27. PMID 21050177 DOI: 10.2174/156802611795371332 |
0.745 |
|
| 2011 |
Nickell JR, Zheng G, Deaciuc AG, Crooks PA, Dwoskin LP. Phenyl ring-substituted lobelane analogs: inhibition of [³H]dopamine uptake at the vesicular monoamine transporter-2. The Journal of Pharmacology and Experimental Therapeutics. 336: 724-33. PMID 20876747 DOI: 10.1124/Jpet.110.172882 |
0.456 |
|
| 2011 |
Perry JL, Joseph JE, Jiang Y, Zimmerman RS, Kelly TH, Darna M, Huettl P, Dwoskin LP, Bardo MT. Prefrontal cortex and drug abuse vulnerability: translation to prevention and treatment interventions. Brain Research Reviews. 65: 124-49. PMID 20837060 DOI: 10.1016/J.Brainresrev.2010.09.001 |
0.303 |
|
| 2010 |
Smith AM, Dwoskin LP, Pauly JR. Early exposure to nicotine during critical periods of brain development: Mechanisms and consequences. Journal of Pediatric Biochemistry. 1: 125-141. PMID 24904708 DOI: 10.3233/Jpb-2010-0012 |
0.418 |
|
| 2010 |
Beckmann JS, Siripurapu KB, Nickell JR, Horton DB, Denehy ED, Vartak A, Crooks PA, Dwoskin LP, Bardo MT. The novel pyrrolidine nor-lobelane analog UKCP-110 [cis-2,5-di-(2-phenethyl)-pyrrolidine hydrochloride] inhibits VMAT2 function, methamphetamine-evoked dopamine release, and methamphetamine self-administration in rats. The Journal of Pharmacology and Experimental Therapeutics. 335: 841-51. PMID 20805303 DOI: 10.1124/Jpet.110.172742 |
0.782 |
|
| 2010 |
Meyer AC, Rahman S, Charnigo RJ, Dwoskin LP, Crabbe JC, Bardo MT. Genetics of novelty seeking, amphetamine self-administration and reinstatement using inbred rats. Genes, Brain, and Behavior. 9: 790-8. PMID 20618445 DOI: 10.1111/J.1601-183X.2010.00616.X |
0.333 |
|
| 2010 |
Smith AM, Pivavarchyk M, Wooters TE, Zhang Z, Zheng G, McIntosh JM, Crooks PA, Bardo MT, Dwoskin LP. Repeated nicotine administration robustly increases bPiDDB inhibitory potency at alpha6beta2-containing nicotinic receptors mediating nicotine-evoked dopamine release. Biochemical Pharmacology. 80: 402-9. PMID 20346923 DOI: 10.1016/J.Bcp.2010.03.018 |
0.512 |
|
| 2010 |
Zhang Z, Pivavarchyk M, Subramanian KL, Deaciuc AG, Dwoskin LP, Crooks PA. Novel bis-2,2,6,6-tetramethylpiperidine (bis-TMP) and bis-mecamylamine antagonists at neuronal nicotinic receptors mediating nicotine-evoked dopamine release. Bioorganic & Medicinal Chemistry Letters. 20: 1420-3. PMID 20079634 DOI: 10.1016/J.Bmcl.2009.12.089 |
0.52 |
|
| 2010 |
Geldenhuys WJ, Manda VK, Mittapalli RK, Van der Schyf CJ, Crooks PA, Dwoskin LP, Allen DD, Lockman PR. Predictive screening model for potential vector-mediated transport of cationic substrates at the blood-brain barrier choline transporter. Bioorganic & Medicinal Chemistry Letters. 20: 870-7. PMID 20053562 DOI: 10.1016/J.Bmcl.2009.12.079 |
0.396 |
|
| 2010 |
Hojahmat M, Horton DB, Norrholm SD, Miller DK, Grinevich VP, Deaciuc AG, Dwoskin LP, Crooks PA. Lobeline esters as novel ligands for neuronal nicotinic acetylcholine receptors and neurotransmitter transporters. Bioorganic & Medicinal Chemistry. 18: 640-9. PMID 20036131 DOI: 10.1016/J.Bmc.2009.12.002 |
0.795 |
|
| 2010 |
Nickell JR, Krishnamurthy S, Norrholm S, Deaciuc G, Siripurapu KB, Zheng G, Crooks PA, Dwoskin LP. Lobelane inhibits methamphetamine-evoked dopamine release via inhibition of the vesicular monoamine transporter-2. The Journal of Pharmacology and Experimental Therapeutics. 332: 612-21. PMID 19855096 DOI: 10.1124/Jpet.109.160275 |
0.699 |
|
| 2010 |
Holtman J, Dwoskin L, Wala E, Crooks P, McIntosch J. Novel small molecule alpha9 alpha10 nicotinic receptor antagonists for pain management The Journal of Pain. 11: S33. DOI: 10.1016/J.Jpain.2010.01.138 |
0.308 |
|
| 2009 |
Zheng G, Dwoskin LP, Deaciuc AG, Crooks PA. Stereocontrolled synthesis and pharmacological evaluation of cis-2,6-diphenethyl-1-azabicyclo[2.2.2]octanes as lobelane analogues. The Journal of Organic Chemistry. 74: 6072-6. PMID 20560567 DOI: 10.1021/Jo901082R |
0.316 |
|
| 2009 |
Struthers AM, Wilkinson JL, Dwoskin LP, Crooks PA, Bevins RA. Mecamylamine, dihydro-beta-erythroidine, and dextromethorphan block conditioned responding evoked by the conditional stimulus effects of nicotine. Pharmacology, Biochemistry, and Behavior. 94: 319-28. PMID 19778551 DOI: 10.1016/J.Pbb.2009.09.012 |
0.421 |
|
| 2009 |
Vartak AP, Nickell JR, Chagkutip J, Dwoskin LP, Crooks PA. Pyrrolidine analogues of lobelane: relationship of affinity for the dihydrotetrabenazine binding site with function of the vesicular monoamine transporter 2 (VMAT2). Journal of Medicinal Chemistry. 52: 7878-82. PMID 19691331 DOI: 10.1021/Jm900770H |
0.31 |
|
| 2009 |
Smith AM, Dhawan GK, Zhang Z, Siripurapu KB, Crooks PA, Dwoskin LP. The novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB), inhibits nicotine-evoked [(3)H]norepinephrine overflow from rat hippocampal slices. Biochemical Pharmacology. 78: 889-97. PMID 19631612 DOI: 10.1016/J.Bcp.2009.07.010 |
0.51 |
|
| 2009 |
López-Hernández GY, Thinschmidt JS, Zheng G, Zhang Z, Crooks PA, Dwoskin LP, Papke RL. Selective inhibition of acetylcholine-evoked responses of alpha7 neuronal nicotinic acetylcholine receptors by novel tris- and tetrakis-azaaromatic quaternary ammonium antagonists. Molecular Pharmacology. 76: 652-66. PMID 19556356 DOI: 10.1124/Mol.109.056176 |
0.404 |
|
| 2009 |
Dwoskin LP, Smith AM, Wooters TE, Zhang Z, Crooks PA, Bardo MT. Nicotinic receptor-based therapeutics and candidates for smoking cessation. Biochemical Pharmacology. 78: 732-43. PMID 19523455 DOI: 10.1016/J.Bcp.2009.06.002 |
0.468 |
|
| 2009 |
Zheng F, McConnell MJ, Zhan CG, Dwoskin LP, Crooks PA. QSAR study on maximal inhibition (Imax) of quaternary ammonium antagonists for S-(-)-nicotine-evoked dopamine release from dopaminergic nerve terminals in rat striatum. Bioorganic & Medicinal Chemistry. 17: 4477-85. PMID 19477134 DOI: 10.1016/J.Bmc.2009.05.010 |
0.497 |
|
| 2009 |
Zhu J, Apparsundaram S, Dwoskin LP. Nicotinic receptor activation increases [3H]dopamine uptake and cell surface expression of dopamine transporters in rat prefrontal cortex. The Journal of Pharmacology and Experimental Therapeutics. 328: 931-9. PMID 19088301 DOI: 10.1124/Jpet.108.147025 |
0.566 |
|
| 2009 |
Dwoskin LP, Bardo MT. Targeting nicotinic receptor antagonists as novel pharmacotherapies for tobacco dependence and relapse. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 244-6. PMID 19079069 DOI: 10.1038/Npp.2008.157 |
0.402 |
|
| 2009 |
Dwoskin LP, Pivavarchyk M, Joyce BM, Neugebauer NM, Zheng G, Zhang Z, Bardo MT, Crooks PA. Targeting reward-relevant nicotinic receptors in the discovery of novel pharmacotherapeutic agents to treat tobacco dependence. Nebraska Symposium On Motivation. Nebraska Symposium On Motivation. 55: 31-63. PMID 19013938 DOI: 10.1007/978-0-387-78748-0_4 |
0.388 |
|
| 2009 |
Zheng F, Zheng G, Deaciuc AG, Zhan CG, Dwoskin LP, Crooks PA. Computational neural network analysis of the affinity of N-n-alkylnicotinium salts for the alpha4beta2* nicotinic acetylcholine receptor. Journal of Enzyme Inhibition and Medicinal Chemistry. 24: 157-68. PMID 18629679 DOI: 10.1080/14756360801945648 |
0.328 |
|
| 2009 |
McIntosh J, Dwoskin L, Crooks P, Holtman J. GZ556A and ZZ204G are novel small molecule antagonists of α9α10 nAChRs and are analgesic in rats Biochemical Pharmacology. 78: 921. DOI: 10.1016/J.Bcp.2009.06.084 |
0.354 |
|
| 2008 |
Rahman S, Neugebauer NM, Zhang Z, Crooks PA, Dwoskin LP, Bardo MT. The novel nicotinic receptor antagonist N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide decreases nicotine-induced dopamine metabolism in rat nucleus accumbens. European Journal of Pharmacology. 601: 103-5. PMID 19000671 DOI: 10.1016/J.Ejphar.2008.10.037 |
0.507 |
|
| 2008 |
Zheng G, Dwoskin LP, Deaciuc AG, Crooks PA. Synthesis and evaluation of a series of homologues of lobelane at the vesicular monoamine transporter-2. Bioorganic & Medicinal Chemistry Letters. 18: 6509-12. PMID 18976906 DOI: 10.1016/J.Bmcl.2008.10.042 |
0.323 |
|
| 2008 |
Zhang Z, Zheng G, Pivavarchyk M, Deaciuc AG, Dwoskin LP, Crooks PA. Tetrakis-azaaromatic quaternary ammonium salts: novel subtype-selective antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release. Bioorganic & Medicinal Chemistry Letters. 18: 5753-7. PMID 18851914 DOI: 10.1016/J.Bmcl.2008.09.084 |
0.475 |
|
| 2008 |
Zhang Z, Lockman PR, Mittapalli RK, Allen DD, Dwoskin LP, Crooks PA. bis-Pyridinium cyclophanes: novel ligands with high affinity for the blood-brain barrier choline transporter. Bioorganic & Medicinal Chemistry Letters. 18: 5622-5. PMID 18793853 DOI: 10.1016/J.Bmcl.2008.08.099 |
0.332 |
|
| 2008 |
Albayati ZA, Dwoskin LP, Crooks PA. Pharmacokinetics of the novel nicotinic receptor antagonist N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide in the rat. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 2024-9. PMID 18617603 DOI: 10.1124/Dmd.108.020354 |
0.316 |
|
| 2008 |
Dwoskin LP, Wooters TE, Sumithran SP, Siripurapu KB, Joyce BM, Lockman PR, Manda VK, Ayers JT, Zhang Z, Deaciuc AG, McIntosh JM, Crooks PA, Bardo MT. N,N'-Alkane-diyl-bis-3-picoliniums as nicotinic receptor antagonists: inhibition of nicotine-evoked dopamine release and hyperactivity. The Journal of Pharmacology and Experimental Therapeutics. 326: 563-76. PMID 18460644 DOI: 10.1124/Jpet.108.136630 |
0.528 |
|
| 2008 |
Papke RL, Dwoskin LP, Crooks PA, Zheng G, Zhang Z, McIntosh JM, Stokes C. Extending the analysis of nicotinic receptor antagonists with the study of alpha6 nicotinic receptor subunit chimeras. Neuropharmacology. 54: 1189-200. PMID 18448138 DOI: 10.1016/J.Neuropharm.2008.03.010 |
0.327 |
|
| 2008 |
Rahman S, Zhang Z, Papke RL, Crooks PA, Dwoskin LP, Bardo MT. Region-specific effects of N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide on nicotine-induced increase in extracellular dopamine in vivo. British Journal of Pharmacology. 153: 792-804. PMID 18059317 DOI: 10.1038/Sj.Bjp.0707612 |
0.532 |
|
| 2008 |
Lockman PR, Manda VK, Geldenhuys WJ, Mittapalli RK, Thomas F, Albayati ZF, Crooks PA, Dwoskin LP, Allen DD. Carrier-mediated transport of the quaternary ammonium neuronal nicotinic receptor antagonist n,n'-dodecylbispicolinium dibromide at the blood-brain barrier. The Journal of Pharmacology and Experimental Therapeutics. 324: 244-50. PMID 17921191 DOI: 10.1124/Jpet.107.130906 |
0.436 |
|
| 2007 |
Zheng G, Zhang Z, Pivavarchyk M, Deaciuc AG, Dwoskin LP, Crooks PA. Bis-azaaromatic quaternary ammonium salts as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release: An investigation of binding conformation. Bioorganic & Medicinal Chemistry Letters. 17: 6734-8. PMID 18029180 DOI: 10.1016/J.Bmcl.2007.10.052 |
0.511 |
|
| 2007 |
Norrholm SD, Horton DB, Dwoskin LP. The promiscuity of the dopamine transporter: implications for the kinetic analysis of [3H]serotonin uptake in rat hippocampal and striatal synaptosomes. Neuropharmacology. 53: 982-9. PMID 18022203 DOI: 10.1016/J.Neuropharm.2007.10.001 |
0.788 |
|
| 2007 |
Zheng G, Sumithran SP, Deaciuc AG, Dwoskin LP, Crooks PA. Tris-azaaromatic quaternary ammonium salts: Novel templates as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release. Bioorganic & Medicinal Chemistry Letters. 17: 6701-6. PMID 17977723 DOI: 10.1016/J.Bmcl.2007.10.062 |
0.535 |
|
| 2007 |
Zhu J, Bardo MT, Green TA, Wedlund PJ, Dwoskin LP. Nicotine increases dopamine clearance in medial prefrontal cortex in rats raised in an enriched environment. Journal of Neurochemistry. 103: 2575-88. PMID 17953677 DOI: 10.1111/J.1471-4159.2007.04951.X |
0.539 |
|
| 2007 |
Dwoskin LP, Joyce BM, Zheng G, Neugebauer NM, Manda VK, Lockman P, Papke RL, Bardo MT, Crooks PA. Discovery of a novel nicotinic receptor antagonist for the treatment of nicotine addiction: 1-(3-Picolinium)-12-triethylammonium-dodecane dibromide (TMPD). Biochemical Pharmacology. 74: 1271-82. PMID 17727820 DOI: 10.1016/J.Bcp.2007.07.021 |
0.526 |
|
| 2007 |
Zhu J, Bardo MT, Bruntz RC, Stairs DJ, Dwoskin LP. Individual differences in response to novelty predict prefrontal cortex dopamine transporter function and cell surface expression. The European Journal of Neuroscience. 26: 717-28. PMID 17651428 DOI: 10.1111/J.1460-9568.2007.05690.X |
0.525 |
|
| 2007 |
Neugebauer NM, Harrod SB, Stairs DJ, Crooks PA, Dwoskin LP, Bardo MT. Lobelane decreases methamphetamine self-administration in rats. European Journal of Pharmacology. 571: 33-8. PMID 17612524 DOI: 10.1016/J.Ejphar.2007.06.003 |
0.37 |
|
| 2007 |
Papke RL, Dwoskin LP, Crooks PA. The pharmacological activity of nicotine and nornicotine on nAChRs subtypes: relevance to nicotine dependence and drug discovery. Journal of Neurochemistry. 101: 160-7. PMID 17241116 DOI: 10.1111/J.1471-4159.2006.04355.X |
0.424 |
|
| 2007 |
Middleton LS, Crooks PA, Wedlund PJ, Cass WA, Dwoskin LP. Nornicotine inhibition of dopamine transporter function in striatum via nicotinic receptor activation. Synapse (New York, N.Y.). 61: 157-65. PMID 17146768 DOI: 10.1002/Syn.20351 |
0.749 |
|
| 2007 |
Middleton LS, Apparsundaram S, King-Pospisil KA, Dwoskin LP. Nicotine increases dopamine transporter function in rat striatum through a trafficking-independent mechanism. European Journal of Pharmacology. 554: 128-36. PMID 17141211 DOI: 10.1016/J.Ejphar.2006.09.074 |
0.523 |
|
| 2007 |
Rahman S, Neugebauer NM, Zhang Z, Crooks PA, Dwoskin LP, Bardo MT. The effects of a novel nicotinic receptor antagonist N,N-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB) on acute and repeated nicotine-induced increases in extracellular dopamine in rat nucleus accumbens. Neuropharmacology. 52: 755-63. PMID 17097117 DOI: 10.1016/J.Neuropharm.2006.09.012 |
0.513 |
|
| 2007 |
Stairs DJ, Neugebauer NM, Wei X, Boustany C, Hojahmat M, Cassis LA, Crooks PA, Dwoskin LP, Bardo MT. Effects of nornicotine enantiomers on intravenous S(-)-nicotine self-administration and cardiovascular function in rats. Psychopharmacology. 190: 145-55. PMID 17096082 DOI: 10.1007/S00213-006-0610-1 |
0.408 |
|
| 2007 |
Bardo MT, Williams Y, Dwoskin LP, Moynahan SE, Perry IB, Martin CA. The sensation seeking trait and substance use: Research findings and clinical implications Current Psychiatry Reviews. 3: 3-13. DOI: 10.2174/157340007779815682 |
0.778 |
|
| 2006 |
Chen J, Deaciuc AG, Dwoskin LP, Crooks PA, Bai D. N, N -disubstituted piperazines and homopiperazines: synthesis and affinities at alpha4beta2* and alpha7* neuronal nicotinic acetylcholine receptors. Journal of Enzyme Inhibition and Medicinal Chemistry. 21: 667-80. PMID 17252939 DOI: 10.1080/14756360600900513 |
0.391 |
|
| 2006 |
Zheng G, Dwoskin LP, Crooks PA. Vesicular monoamine transporter 2: role as a novel target for drug development. The Aaps Journal. 8: E682-92. PMID 17233532 DOI: 10.1208/Aapsj080478 |
0.382 |
|
| 2006 |
Dwoskin LP, Rauhut AS, King-Pospisil KA, Bardo MT. Review of the pharmacology and clinical profile of bupropion, an antidepressant and tobacco use cessation agent. Cns Drug Reviews. 12: 178-207. PMID 17227286 DOI: 10.1111/J.1527-3458.2006.00178.X |
0.492 |
|
| 2006 |
Huang X, Zheng F, Chen X, Crooks PA, Dwoskin LP, Zhan CG. Modeling subtype-selective agonists binding with alpha4beta2 and alpha7 nicotinic acetylcholine receptors: effects of local binding and long-range electrostatic interactions. Journal of Medicinal Chemistry. 49: 7661-74. PMID 17181149 DOI: 10.1021/Jm0606701 |
0.364 |
|
| 2006 |
Zheng G, Horton DB, Deaciuc AG, Dwoskin LP, Crooks PA. Des-keto lobeline analogs with increased potency and selectivity at dopamine and serotonin transporters. Bioorganic & Medicinal Chemistry Letters. 16: 5018-21. PMID 16905316 DOI: 10.1016/J.Bmcl.2006.07.070 |
0.755 |
|
| 2006 |
Wooters TE, Dwoskin LP, Bardo MT. Age and sex differences in the locomotor effect of repeated methylphenidate in rats classified as high or low novelty responders. Psychopharmacology. 188: 18-27. PMID 16896959 DOI: 10.1007/S00213-006-0445-9 |
0.33 |
|
| 2006 |
Zheng F, Bayram E, Sumithran SP, Ayers JT, Zhan CG, Schmitt JD, Dwoskin LP, Crooks PA. QSAR modeling of mono- and bis-quaternary ammonium salts that act as antagonists at neuronal nicotinic acetylcholine receptors mediating dopamine release. Bioorganic & Medicinal Chemistry. 14: 3017-37. PMID 16431111 DOI: 10.1016/J.Bmc.2005.12.036 |
0.395 |
|
| 2006 |
Neugebauer NM, Zhang Z, Crooks PA, Dwoskin LP, Bardo MT. Effect of a novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide, on nicotine self-administration and hyperactivity in rats. Psychopharmacology. 184: 426-34. PMID 16220336 DOI: 10.1007/S00213-005-0163-8 |
0.479 |
|
| 2005 |
Wilkins LH, Miller DK, Ayers JT, Crooks PA, Dwoskin LP. N-n-alkylnicotinium analogs, a novel class of antagonists at alpha 4 beta 2* nicotinic acetylcholine receptors: inhibition of S(-)-nicotine-evoked 86Rb+ efflux from rat thalamic synaptosomes. The Aaps Journal. 7: E922-30. PMID 16594645 DOI: 10.1208/Aapsj070490 |
0.781 |
|
| 2005 |
Ayers JT, Xu R, Dwoskin LP, Crooks PA. A general procedure for the enantioselective synthesis of the minor tobacco alkaloids nornicotine, anabasine, and anatabine. The Aaps Journal. 7: E752-8. PMID 16353951 DOI: 10.1208/Aapsj070375 |
0.324 |
|
| 2005 |
Ayers JT, Clauset A, Schmitt JD, Dwoskin LP, Crooks PA. Molecular modeling of mono- and bis-quaternary ammonium salts as ligands at the alpha4beta2 nicotinic acetylcholine receptor subtype using nonlinear techniques. The Aaps Journal. 7: E678-85. PMID 16353944 DOI: 10.1208/Aapsj070368 |
0.347 |
|
| 2005 |
Rauhut AS, Dwoskin LP, Bardo MT. Tolerance does not develop to the decrease in nicotine self-administration produced by repeated bupropion administration. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 7: 901-7. PMID 16298725 DOI: 10.1080/14622200500381384 |
0.406 |
|
| 2005 |
Huang X, Zheng F, Crooks PA, Dwoskin LP, Zhan CG. Modeling multiple species of nicotine and deschloroepibatidine interacting with alpha4beta2 nicotinic acetylcholine receptor: from microscopic binding to phenomenological binding affinity. Journal of the American Chemical Society. 127: 14401-14. PMID 16218635 DOI: 10.1021/Ja052681+ |
0.353 |
|
| 2005 |
Wei X, Sumithran SP, Deaciuc AG, Burton HR, Bush LP, Dwoskin LP, Crooks PA. Identification and synthesis of novel alkaloids from the root system of Nicotiana tabacum: affinity for neuronal nicotinic acetylcholine receptors. Life Sciences. 78: 495-505. PMID 16197964 DOI: 10.1016/J.Lfs.2005.09.009 |
0.496 |
|
| 2005 |
Sumithran SP, Crooks PA, Xu R, Zhu J, Deaciuc AG, Wilkins LH, Dwoskin LP. Introduction of unsaturation into the N-n-alkyl chain of the nicotinic receptor antagonists, NONI and NDNI: effect on affinity and selectivity. The Aaps Journal. 7: E201-17. PMID 16146341 DOI: 10.1208/Aapsj070119 |
0.81 |
|
| 2005 |
Zheng G, Dwoskin LP, Deaciuc AG, Crooks PA. Synthesis and evaluation of a series of tropane analogues as novel vesicular monoamine transporter-2 ligands. Bioorganic & Medicinal Chemistry Letters. 15: 4463-6. PMID 16112864 DOI: 10.1016/J.Bmcl.2005.07.032 |
0.396 |
|
| 2005 |
Zheng G, Dwoskin LP, Deaciuc AG, Norrholm SD, Crooks PA. Defunctionalized lobeline analogues: structure-activity of novel ligands for the vesicular monoamine transporter. Journal of Medicinal Chemistry. 48: 5551-60. PMID 16107155 DOI: 10.1021/Jm0501228 |
0.67 |
|
| 2005 |
Papke RL, Zheng G, Horenstein NA, Dwoskin LP, Crooks PA. The characterization of a novel rigid nicotine analog with alpha7-selective nAChR agonist activity and modulation of agonist properties by boron inclusion. Bioorganic & Medicinal Chemistry Letters. 15: 3874-80. PMID 16005216 DOI: 10.1016/J.Bmcl.2005.05.118 |
0.386 |
|
| 2005 |
Zhu J, Apparsundaram S, Bardo MT, Dwoskin LP. Environmental enrichment decreases cell surface expression of the dopamine transporter in rat medial prefrontal cortex. Journal of Neurochemistry. 93: 1434-43. PMID 15935059 DOI: 10.1111/J.1471-4159.2005.03130.X |
0.481 |
|
| 2005 |
Zheng G, Dwoskin LP, Deaciuc AG, Zhu J, Jones MD, Crooks PA. Lobelane analogues as novel ligands for the vesicular monoamine transporter-2. Bioorganic & Medicinal Chemistry. 13: 3899-909. PMID 15911306 DOI: 10.1016/J.Bmc.2005.04.013 |
0.351 |
|
| 2005 |
Geldenhuys WJ, Lockman PR, Nguyen TH, Van der Schyf CJ, Crooks PA, Dwoskin LP, Allen DD. 3D-QSAR study of bis-azaaromatic quaternary ammonium analogs at the blood-brain barrier choline transporter. Bioorganic & Medicinal Chemistry. 13: 4253-61. PMID 15878282 DOI: 10.1016/J.Bmc.2005.04.020 |
0.319 |
|
| 2005 |
Dwoskin L, Zhu J, Cain M, Bardo M. A108 INDIVIDUAL DIFFERENCES IN NICOTINE-INDUCED HYPERACTIVITY AND NICOTINE-INDUCED AUGMENTATION OF DOPAMINE TRANSPORTER FUNCTION AND TRAFFICKING TO THE CELL SURFACE IN PREFRONTAL CORTEX IN RATS Behavioural Pharmacology. 16: S57. DOI: 10.1097/00008877-200509001-00181 |
0.36 |
|
| 2004 |
Neugebauer NM, Cunningham ST, Zhu J, Bryant RI, Middleton LS, Dwoskin LP. Effects of environmental enrichment on behavior and dopamine transporter function in medial prefrontal cortex in adult rats prenatally treated with cocaine. Brain Research. Developmental Brain Research. 153: 213-23. PMID 15527889 DOI: 10.1016/J.Devbrainres.2004.09.001 |
0.446 |
|
| 2004 |
Harrod SB, Dwoskin LP, Bardo MT. Lobeline produces conditioned taste avoidance in rats. Pharmacology, Biochemistry, and Behavior. 78: 1-5. PMID 15159128 DOI: 10.1016/J.Pbb.2004.01.011 |
0.348 |
|
| 2004 |
Miller DK, Crooks PA, Zheng G, Grinevich VP, Norrholm SD, Dwoskin LP. Lobeline analogs with enhanced affinity and selectivity for plasmalemma and vesicular monoamine transporters. The Journal of Pharmacology and Experimental Therapeutics. 310: 1035-45. PMID 15121762 DOI: 10.1124/Jpet.104.068098 |
0.69 |
|
| 2004 |
Crooks PA, Ayers JT, Xu R, Sumithran SP, Grinevich VP, Wilkins LH, Deaciuc AG, Allen DD, Dwoskin LP. Development of subtype-selective ligands as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release. Bioorganic & Medicinal Chemistry Letters. 14: 1869-74. PMID 15050618 DOI: 10.1016/J.Bmcl.2003.10.074 |
0.804 |
|
| 2004 |
Dwoskin LP, Sumithran SP, Zhu J, Deaciuc AG, Ayers JT, Crooks PA. Subtype-selective nicotinic receptor antagonists: potential as tobacco use cessation agents. Bioorganic & Medicinal Chemistry Letters. 14: 1863-7. PMID 15050617 DOI: 10.1016/J.Bmcl.2003.10.073 |
0.521 |
|
| 2004 |
Zhu J, Green T, Bardo MT, Dwoskin LP. Environmental enrichment enhances sensitization to GBR 12935-induced activity and decreases dopamine transporter function in the medial prefrontal cortex. Behavioural Brain Research. 148: 107-17. PMID 14684252 DOI: 10.1016/S0166-4328(03)00190-6 |
0.506 |
|
| 2004 |
Middleton LS, Cass WA, Dwoskin LP. Nicotinic receptor modulation of dopamine transporter function in rat striatum and medial prefrontal cortex. The Journal of Pharmacology and Experimental Therapeutics. 308: 367-77. PMID 14563785 DOI: 10.1124/Jpet.103.055335 |
0.726 |
|
| 2003 |
Rauhut AS, Neugebauer N, Dwoskin LP, Bardo MT. Effect of bupropion on nicotine self-administration in rats. Psychopharmacology. 169: 1-9. PMID 12811464 DOI: 10.1007/S00213-003-1450-X |
0.447 |
|
| 2003 |
Grinevich VP, Crooks PA, Sumithran SP, Haubner AJ, Ayers JT, Dwoskin LP. N-n-alkylpyridinium analogs, a novel class of nicotinic receptor antagonists: selective inhibition of nicotine-evoked [3H] dopamine overflow from superfused rat striatal slices. The Journal of Pharmacology and Experimental Therapeutics. 306: 1011-20. PMID 12766255 DOI: 10.1124/jpet.103.051789 |
0.364 |
|
| 2003 |
Allen DD, Lockman PR, Roder KE, Dwoskin LP, Crooks PA. Active transport of high-affinity choline and nicotine analogs into the central nervous system by the blood-brain barrier choline transporter. The Journal of Pharmacology and Experimental Therapeutics. 304: 1268-74. PMID 12604705 DOI: 10.1124/Jpet.102.045856 |
0.417 |
|
| 2003 |
Wilkins LH, Grinevich VP, Ayers JT, Crooks PA, Dwoskin LP. N-n-alkylnicotinium analogs, a novel class of nicotinic receptor antagonists: interaction with alpha4beta2* and alpha7* neuronal nicotinic receptors. The Journal of Pharmacology and Experimental Therapeutics. 304: 400-10. PMID 12490617 DOI: 10.1124/Jpet.102.043349 |
0.798 |
|
| 2003 |
Miller DK, Harrod SB, Green TA, Wong MY, Bardo MT, Dwoskin LP. Lobeline attenuates locomotor stimulation induced by repeated nicotine administration in rats. Pharmacology, Biochemistry, and Behavior. 74: 279-86. PMID 12479946 DOI: 10.1016/S0091-3057(02)00996-6 |
0.491 |
|
| 2003 |
Chen J, Norrholm S, Dwoskin LP, Crooks PA, Bai D. N,N-disubstituted piperazines: synthesis and affinities at alpha4beta2(*) and alpha7(*) neuronal nicotinic acetylcholine receptors. Bioorganic & Medicinal Chemistry Letters. 13: 97-100. PMID 12467625 DOI: 10.1016/S0960-894X(02)00849-1 |
0.659 |
|
| 2003 |
Harrod SB, Dwoskin LP, Green TA, Gehrke BJ, Bardo MT. Lobeline does not serve as a reinforcer in rats. Psychopharmacology. 165: 397-404. PMID 12459929 DOI: 10.1007/S00213-002-1289-6 |
0.361 |
|
| 2003 |
Zhu J, Crooks PA, Ayers JT, Sumithran SP, Dwoskin LP. N-n-Alkylnicotinium and N-n-Alkylpyridinium Analogs Inhibit the Dopamine Transporter: Selectivity as Nicotinic Receptor Antagonists Drug Development Research. 60: 270-284. DOI: 10.1002/Ddr.10328 |
0.547 |
|
| 2002 |
Rauhut AS, Mullins SN, Dwoskin LP, Bardo MT. Reboxetine: attenuation of intravenous nicotine self-administration in rats. The Journal of Pharmacology and Experimental Therapeutics. 303: 664-72. PMID 12388649 DOI: 10.1124/Jpet.303.2.664 |
0.451 |
|
| 2002 |
Green TA, Brown RW, Phillips SB, Dwoskin LP, Bardo MT. Locomotor stimulant effects of nornicotine: role of dopamine. Pharmacology, Biochemistry, and Behavior. 74: 87-94. PMID 12376155 DOI: 10.1016/S0091-3057(02)00960-7 |
0.474 |
|
| 2002 |
Ayers JT, Dwoskin LP, Deaciuc AG, Grinevich VP, Zhu J, Crooks PA. bis-Azaaromatic quaternary ammonium analogues: ligands for alpha4beta2* and alpha7* subtypes of neuronal nicotinic receptors. Bioorganic & Medicinal Chemistry Letters. 12: 3067-71. PMID 12372503 DOI: 10.1016/S0960-894X(02)00687-X |
0.521 |
|
| 2002 |
Miller DK, Sumithran SP, Dwoskin LP. Bupropion inhibits nicotine-evoked [(3)H]overflow from rat striatal slices preloaded with [(3)H]dopamine and from rat hippocampal slices preloaded with [(3)H]norepinephrine. The Journal of Pharmacology and Experimental Therapeutics. 302: 1113-22. PMID 12183670 DOI: 10.1124/Jpet.102.033852 |
0.508 |
|
| 2002 |
Miller DK, Wong EH, Chesnut MD, Dwoskin LP. Reboxetine: functional inhibition of monoamine transporters and nicotinic acetylcholine receptors. The Journal of Pharmacology and Experimental Therapeutics. 302: 687-95. PMID 12130733 DOI: 10.1124/Jpet.302.2.687 |
0.496 |
|
| 2002 |
Wilkins LH, Haubner A, Ayers JT, Crooks PA, Dwoskin LP. N-n-alkylnicotinium analogs, a novel class of nicotinic receptor antagonist: inhibition of S(-)-nicotine-evoked [(3)H]dopamine overflow from superfused rat striatal slices. The Journal of Pharmacology and Experimental Therapeutics. 301: 1088-96. PMID 12023541 DOI: 10.1124/Jpet.301.3.1088 |
0.787 |
|
| 2002 |
Maragos WF, Zhu J, Chesnut MD, Dwoskin LP. Mitochondrial toxin inhibition of [(3)H]dopamine uptake into rat striatal synaptosomes. Biochemical Pharmacology. 63: 1499-505. PMID 11996892 DOI: 10.1016/S0006-2952(02)00910-3 |
0.488 |
|
| 2002 |
Dwoskin LP, Crooks PA. A novel mechanism of action and potential use for lobeline as a treatment for psychostimulant abuse. Biochemical Pharmacology. 63: 89-98. PMID 11841781 DOI: 10.1016/S0006-2952(01)00899-1 |
0.539 |
|
| 2002 |
Xu R, Dwoskin LP, Grinevich V, Sumithran SP, Crooks PA. Synthesis and evaluation of conformationally restricted pyridino N-alkylated nicotine analogs as nicotinic acetylcholine receptor antagonists Drug Development Research. 55: 173-186. DOI: 10.1002/Ddr.10049 |
0.494 |
|
| 2001 |
Dwoskin LP, Teng LH, Crooks PA. Nornicotine, a nicotine metabolite and tobacco alkaloid: desensitization of nicotinic receptor-stimulated dopamine release from rat striatum. European Journal of Pharmacology. 428: 69-79. PMID 11779039 DOI: 10.1016/S0014-2999(01)01283-3 |
0.482 |
|
| 2001 |
Green TA, Crooks PA, Bardo MT, Dwoskin LP. Contributory role for nornicotine in nicotine neuropharmacology: nornicotine-evoked [3H]dopamine overflow from rat nucleus accumbens slices. Biochemical Pharmacology. 62: 1597-603. PMID 11755112 DOI: 10.1016/S0006-2952(01)00838-3 |
0.529 |
|
| 2001 |
Truong A, Xing X, Forsayeth JR, Dwoskin LP, Crooks PA, Cohen BN. Pharmacological differences between immunoisolated native brain and heterologously expressed rat alpha4beta2 nicotinic receptors. Brain Research. Molecular Brain Research. 96: 68-76. PMID 11731010 DOI: 10.1016/S0169-328X(01)00268-6 |
0.394 |
|
| 2001 |
Miller DK, Wilkins LH, Bardo MT, Crooks PA, Dwoskin LP. Once weekly administration of nicotine produces long-lasting locomotor sensitization in rats via a nicotinic receptor-mediated mechanism. Psychopharmacology. 156: 469-76. PMID 11498725 DOI: 10.1007/S002130100747 |
0.783 |
|
| 2001 |
Xu R, Dwoskin LP, Grinevich VP, Deaciuc G, Crooks PA. Neuronal nicotinic acetylcholine receptor binding affinities of boron-containing nicotine analogues. Bioorganic & Medicinal Chemistry Letters. 11: 1245-8. PMID 11354387 DOI: 10.1016/S0960-894X(01)00193-7 |
0.441 |
|
| 2001 |
Butt CM, Pauly JR, Wilkins LH, Dwoskin LP, Debski EA. Pharmacology, distribution and development of muscarinic acetylcholine receptor subtypes in the optic tectum of Rana pipiens. Neuroscience. 104: 161-79. PMID 11311540 DOI: 10.1016/S0306-4522(01)00048-3 |
0.745 |
|
| 2001 |
Miller DK, Crooks PA, Teng L, Witkin JM, Munzar P, Goldberg SR, Acri JB, Dwoskin LP. Lobeline inhibits the neurochemical and behavioral effects of amphetamine. The Journal of Pharmacology and Experimental Therapeutics. 296: 1023-34. PMID 11181937 |
0.361 |
|
| 2000 |
Green TA, Phillips SB, Crooks PA, Dwoskin LP, Bardo MT. Nornicotine pretreatment decreases intravenous nicotine self-administration in rats. Psychopharmacology. 152: 289-94. PMID 11105939 DOI: 10.1007/S002130000524 |
0.426 |
|
| 2000 |
Miller DK, Crooks PA, Dwoskin LP. Lobeline inhibits nicotine-evoked [(3)H]dopamine overflow from rat striatal slices and nicotine-evoked (86)Rb(+) efflux from thalamic synaptosomes. Neuropharmacology. 39: 2654-62. PMID 11044735 DOI: 10.1016/S0028-3908(00)00140-4 |
0.501 |
|
| 2000 |
Dwoskin LP, Xu R, Ayers JT, Crooks PA. Recent developments in neuronal nicotinic acetylcholine receptor antagonists Expert Opinion On Therapeutic Patents. 10: 1561-1581. DOI: 10.1517/13543776.10.10.1561 |
0.381 |
|
| 1999 |
Maragos WF, Jakel RJ, Chesnut MD, Geddes JW, Dwoskin LP. Does dopamine contribute to striatal damage caused by impaired mitochondrial function? Annals of the New York Academy of Sciences. 893: 345-9. PMID 10672263 DOI: 10.1111/J.1749-6632.1999.Tb07851.X |
0.398 |
|
| 1999 |
Shafaee N, Houng M, Truong A, Viseshakul N, Figl A, Sandhu S, Forsayeth JR, Dwoskin LP, Crooks PA, Cohen BN. Pharmacological similarities between native brain and heterologously expressed alpha4beta2 nicotinic receptors. British Journal of Pharmacology. 128: 1291-9. PMID 10578144 DOI: 10.1038/Sj.Bjp.0702900 |
0.394 |
|
| 1999 |
Bardo MT, Green TA, Crooks PA, Dwoskin LP. Nornicotine is self-administered intravenously by rats. Psychopharmacology. 146: 290-6. PMID 10541729 DOI: 10.1007/S002130051119 |
0.409 |
|
| 1999 |
Dwoskin LP, Crooks PA, Teng L, Green TA, Bardo MT. Acute and chronic effects of nornicotine on locomotor activity in rats: altered response to nicotine. Psychopharmacology. 145: 442-51. PMID 10460322 DOI: 10.1007/S002130051079 |
0.425 |
|
| 1999 |
Dwoskin LP, Wilkins LH, Pauly JR, Crooks PA. Development of a novel class of subtype-selective nicotinic receptor antagonist: pyridine-N-substituted nicotine analogs. Annals of the New York Academy of Sciences. 868: 617-9. PMID 10414342 DOI: 10.1111/J.1749-6632.1999.Tb11334.X |
0.777 |
|
| 1999 |
Dwoskin LP, Teng L, Buxton ST, Crooks PA. (S)-(-)-Cotinine, the major brain metabolite of nicotine, stimulates nicotinic receptors to evoke [3H]dopamine release from rat striatal slices in a calcium-dependent manner. The Journal of Pharmacology and Experimental Therapeutics. 288: 905-11. PMID 10027825 |
0.402 |
|
| 1999 |
King VL, Dwoskin LP, Cassis LA. Cold exposure regulates the norepinephrine uptake transporter in rat brown adipose tissue. The American Journal of Physiology. 276: R143-51. PMID 9887188 DOI: 10.1152/Ajpregu.1999.276.1.R143 |
0.357 |
|
| 1999 |
Bardo MT, Valone JM, Robinet PM, Shaw WB, Dwoskin LP. Environmental enrichment enhances the stimulant effect of intravenous amphetamine: Search for a cellular mechanism in the nucleus accumbens Psychobiology. 27: 292-299. DOI: 10.3758/Bf03332123 |
0.462 |
|
| 1998 |
Teng L, Crooks PA, Dwoskin LP. Lobeline displaces [3H]dihydrotetrabenazine binding and releases [3H]dopamine from rat striatal synaptic vesicles: comparison with d-amphetamine. Journal of Neurochemistry. 71: 258-65. PMID 9648873 DOI: 10.1046/J.1471-4159.1998.71010258.X |
0.457 |
|
| 1997 |
Bardo MT, Bevins RA, Klebaur JE, Crooks PA, Dwoskin LP. (-)-Nornicotine partially substitutes for (+)-amphetamine in a drug discrimination paradigm in rats. Pharmacology, Biochemistry, and Behavior. 58: 1083-7. PMID 9408217 DOI: 10.1016/S0091-3057(97)00303-1 |
0.354 |
|
| 1997 |
Teng L, Crooks PA, Buxton ST, Dwoskin LP. Nicotinic-receptor mediation of S(-)nornicotine-evoked -3H-overflow from rat striatal slices preloaded with -3H-dopamine. The Journal of Pharmacology and Experimental Therapeutics. 283: 778-87. PMID 9353398 |
0.409 |
|
| 1997 |
Crooks PA, Dwoskin LP. Contribution of CNS nicotine metabolites to the neuropharmacological effects of nicotine and tobacco smoking. Biochemical Pharmacology. 54: 743-53. PMID 9353128 DOI: 10.1016/S0006-2952(97)00117-2 |
0.422 |
|
| 1997 |
Weed MR, Paul IA, Dwoskin LP, Moore SE, Woolverton WL. The relationship between reinforcing effects and in vitro effects of D1 agonists in monkeys. The Journal of Pharmacology and Experimental Therapeutics. 283: 29-38. PMID 9336305 |
0.319 |
|
| 1997 |
Teng L, Crooks PA, Sonsalla PK, Dwoskin LP. Lobeline and nicotine evoke [3H]overflow from rat striatal slices preloaded with [3H]dopamine: differential inhibition of synaptosomal and vesicular [3H]dopamine uptake. The Journal of Pharmacology and Experimental Therapeutics. 280: 1432-44. PMID 9067333 |
0.419 |
|
| 1995 |
Dwoskin LP, Teng L, Buxton ST, Ravard A, Deo N, Crooks PA. Minor alkaloids of tobacco release [3H]dopamine from superfused rat striatal slices. European Journal of Pharmacology. 276: 195-9. PMID 7781690 DOI: 10.1016/0014-2999(95)00077-X |
0.444 |
|
| 1995 |
Bardo MT, Bowling SL, Rowlett JK, Manderscheid P, Buxton ST, Dwoskin LP. Environmental enrichment attenuates locomotor sensitization, but not in vitro dopamine release, induced by amphetamine. Pharmacology, Biochemistry, and Behavior. 51: 397-405. PMID 7667360 DOI: 10.1016/0091-3057(94)00413-D |
0.431 |
|
| 1995 |
Crooks PA, Ravard A, Wilkins LH, Teng LH, Buxton ST, Dwoskin LP. Inhibition of nicotine-evoked [3H]dopamine release by pyridino N-substituted nicotine analogues: A new class of nicotinic antagonist Drug Development Research. 36: 91-102. DOI: 10.1002/Ddr.430360204 |
0.809 |
|
| 1994 |
Cassis LA, Dwoskin LP. Acute and chronic losartan administration: effect on angiotensin II content and modulation of [3H]norepinephrine release from rat interscapular brown adipose tissue. Journal of Neural Transmission. General Section. 98: 159-64. PMID 7734113 DOI: 10.1007/Bf01277019 |
0.355 |
|
| 1993 |
Dwoskin LP, Buxton ST, Jewell AL, Crooks PA. S(-)-nornicotine increases dopamine release in a calcium-dependent manner from superfused rat striatal slices. Journal of Neurochemistry. 60: 2167-74. PMID 8492124 DOI: 10.1111/J.1471-4159.1993.Tb03502.X |
0.425 |
|
| 1992 |
Dwoskin LP, Leibee LL, Jewell AL, Fang ZX, Crooks PA. Inhibition of [3H]dopamine uptake into rat striatal slices by quaternary N-methylated nicotine metabolites. Life Sciences. 50: PL233-7. PMID 1593921 DOI: 10.1016/0024-3205(92)90533-U |
0.444 |
|
| 1992 |
Dwoskin LP, Jewell AL, Buxton ST, Carney JM. Phencyclidine-induced desensitization of striatal dopamine release. Neuropharmacology. 31: 1033-9. PMID 1436385 DOI: 10.1016/0028-3908(92)90105-X |
0.347 |
|
| 1992 |
Dwoskin LP, Jewell AL, Cassis LA. DuP 753, a nonpeptide angiotensin II-1 receptor antagonist, alters dopaminergic function in rat striatum. Naunyn-Schmiedeberg's Archives of Pharmacology. 345: 153-9. PMID 1314959 DOI: 10.1007/Bf00165730 |
0.435 |
|
| 1991 |
Cassis LA, Dwoskin LP. Presynaptic modulation of neurotransmitter release by endogenous angiotensin II in brown adipose tissue. Journal of Neural Transmission. Supplementum. 34: 129-37. PMID 1667868 DOI: 10.1007/978-3-7091-9175-0_17 |
0.357 |
|
| 1990 |
Peris J, Boyson SJ, Cass WA, Curella P, Dwoskin LP, Larson G, Lin LH, Yasuda RP, Zahniser NR. Persistence of neurochemical changes in dopamine systems after repeated cocaine administration. The Journal of Pharmacology and Experimental Therapeutics. 253: 38-44. PMID 2329520 |
0.79 |
|
| 1989 |
Dwoskin LP, Yasuda RP, Zahniser NR. Irreversible inhibition of rat striatal dopamine uptake induced by in vitro exposure to DSP4. Biochemical Pharmacology. 38: 549-51. PMID 2917012 DOI: 10.1016/0006-2952(89)90400-0 |
0.613 |
|
| 1989 |
Gerhardt GA, Dwoskin LP, Zahniser NR. Outflow and overflow of picogram levels of endogenous dopamine and DOPAC from rat striatal slices: improved methodology for studies of stimulus-evoked release and metabolism. Journal of Neuroscience Methods. 26: 217-27. PMID 2521916 DOI: 10.1016/0165-0270(89)90119-2 |
0.608 |
|
| 1988 |
Dwoskin LP, Peris J, Yasuda RP, Philpott K, Zahniser NR. Repeated cocaine administration results in supersensitivity of striatal D-2 dopamine autoreceptors to pergolide. Life Sciences. 42: 255-62. PMID 3275855 DOI: 10.1016/0024-3205(88)90634-0 |
0.732 |
|
| 1988 |
Zahniser NR, Peris J, Dwoskin LP, Curella P, Yasuda RP, O'Keefe L, Boyson SJ. Sensitization to cocaine in the nigrostriatal dopamine system. Nida Research Monograph. 88: 55-77. PMID 3145458 |
0.717 |
|
| 1988 |
Peris J, Dwoskin LP, Zahniser NR. Biphasic modulation of evoked [3H]D-aspartate release by D-2 dopamine receptors in rat striatal slices. Synapse (New York, N.Y.). 2: 450-6. PMID 2973144 DOI: 10.1002/syn.890020413 |
0.731 |
|
| 1986 |
Dwoskin LP, Zahniser NR. Robust modulation of [3H]dopamine release from rat striatal slices by D-2 dopamine receptors. The Journal of Pharmacology and Experimental Therapeutics. 239: 442-53. PMID 3772803 |
0.617 |
|
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