Tomoko Iwata - Publications

Affiliations: 
University of Glasgow, Glasgow, Scotland, United Kingdom 
Area:
Stem cell

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Year Citation  Score
2023 Hirasawa I, Odagiri H, Park G, Sanghavi R, Oshita T, Togi A, Yoshikawa K, Mizutani K, Takeuchi Y, Kobayashi H, Katagiri S, Iwata T, Aoki A. Anti-inflammatory effects of cold atmospheric plasma irradiation on the THP-1 human acute monocytic leukemia cell line. Plos One. 18: e0292267. PMID 37851686 DOI: 10.1371/journal.pone.0292267  0.309
2014 Foth M, Ahmad I, van Rhijn BW, van der Kwast T, Bergman AM, King L, Ridgway R, Leung HY, Fraser S, Sansom OJ, Iwata T. Fibroblast growth factor receptor 3 activation plays a causative role in urothelial cancer pathogenesis in cooperation with Pten loss in mice. The Journal of Pathology. 233: 148-58. PMID 24519156 DOI: 10.1002/Path.4334  0.412
2012 Ahmad I, Iwata T, Leung HY. Mechanisms of FGFR-mediated carcinogenesis. Biochimica Et Biophysica Acta. 1823: 850-60. PMID 22273505 DOI: 10.1016/J.Bbamcr.2012.01.004  0.308
2009 Thomson RE, Kind PC, Graham NA, Etherson ML, Kennedy J, Fernandes AC, Marques CS, Hevner RF, Iwata T. Fgf receptor 3 activation promotes selective growth and expansion of occipitotemporal cortex. Neural Development. 4: 4. PMID 19192266 DOI: 10.1186/1749-8104-4-4  0.301
2007 Thomson RE, Pellicano F, Iwata T. Fibroblast growth factor receptor 3 kinase domain mutation increases cortical progenitor proliferation via mitogen-activated protein kinase activation Journal of Neurochemistry. 100: 1565-1578. PMID 17181553 DOI: 10.1111/J.1471-4159.2006.04285.X  0.331
2006 Ambrosino C, Iwata T, Scafoglio C, Mallardo M, Klein R, Nebreda AR. TEF-1 and C/EBPbeta are major p38alpha MAPK-regulated transcription factors in proliferating cardiomyocytes. The Biochemical Journal. 396: 163-72. PMID 16492136 DOI: 10.1042/Bj20051502  0.461
2006 Pellicano F, Inglis-Broadgate SL, Pante G, Ansorge W, Iwata T. Expression of coiled-coil protein 1, a novel gene downstream of FGF2, in the developing brain Gene Expression Patterns. 6: 285-293. PMID 16378758 DOI: 10.1016/J.Modgep.2005.07.004  0.301
2005 Pante G, Thompson J, Lamballe F, Iwata T, Ferby I, Barr FA, Davies AM, Maina F, Klein R. Mitogen-inducible gene 6 is an endogenous inhibitor of HGF/Met-induced cell migration and neurite growth. The Journal of Cell Biology. 171: 337-48. PMID 16247031 DOI: 10.1083/Jcb.200502013  0.496
2004 Cho JY, Guo C, Torello M, Lunstrum GP, Iwata T, Deng C, Horton WA. Defective lysosomal targeting of activated fibroblast growth factor receptor 3 in achondroplasia Proceedings of the National Academy of Sciences of the United States of America. 101: 609-614. PMID 14699054 DOI: 10.1073/Pnas.2237184100  0.31
2000 Iwata T, Chen L, Li CL, Ovchinnikov DA, Behringer RR, Francomano CA, Deng CX. A neonatal lethal mutation in FGFR3 uncouples proliferation and differentiation of growth plate chondrocytes in embryos Human Molecular Genetics. 9: 1603-1613. PMID 10861287 DOI: 10.1093/Hmg/9.11.1603  0.326
1999 Li C, Chen L, Iwata T, Kitagawa M, Fu XY, Deng CX. A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors. Human Molecular Genetics. 8: 35-44. PMID 9887329 DOI: 10.1093/Hmg/8.1.35  0.32
Low-probability matches (unlikely to be authored by this person)
2001 Iwata T, Li CL, Deng CX, Francomano CA. Highly activated Fgfr3 with the K644M mutation causes prolonged survival in severe dwarf mice Human Molecular Genetics. 10: 1255-1264. PMID 11406607 DOI: 10.1093/Hmg/10.12.1255  0.297
2005 Inglis-Broadgate SL, Thomson RE, Pellicano F, Tartaglia MA, Pontikis CC, Cooper JD, Iwata T. FGFR3 regulates brain size by controlling progenitor cell proliferation and apoptosis during embryonic development Developmental Biology. 279: 73-85. PMID 15708559 DOI: 10.1016/J.Ydbio.2004.11.035  0.294
2009 Iwata T, Hevner RF. Fibroblast growth factor signaling in development of the cerebral cortex. Development, Growth & Differentiation. 51: 299-323. PMID 19379279 DOI: 10.1111/J.1440-169X.2009.01104.X  0.291
2018 Foth M, Ismail NFB, Kung JSC, Tomlinson D, Knowles MA, Eriksson P, Sjödahl G, Salmond JM, Sansom OJ, Iwata T. FGFR3 mutation increases bladder tumorigenesis by suppressing acute inflammation. The Journal of Pathology. PMID 30043421 DOI: 10.1002/Path.5143  0.289
2011 Ahmad I, Singh LB, Foth M, Morris CA, Taketo MM, Wu XR, Leung HY, Sansom OJ, Iwata T. K-Ras and β-catenin mutations cooperate with Fgfr3 mutations in mice to promote tumorigenesis in the skin and lung, but not in the bladder. Disease Models & Mechanisms. 4: 548-55. PMID 21504907 DOI: 10.1242/Dmm.006874  0.285
2011 Moldrich RX, Mezzera C, Holmes WM, Goda S, Brookfield SJ, Rankin AJ, Barr E, Kurniawan N, Dewar D, Richards LJ, López-Bendito G, Iwata T. Fgfr3 regulates development of the caudal telencephalon. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 1586-99. PMID 21491541 DOI: 10.1002/Dvdy.22636  0.27
2006 Thomson R, Pellicano F, Iwata T. The FGFR3 kinase domain mutation increases cortical progenitor proliferation via MAPK activation International Journal of Developmental Neuroscience. 24: 571. DOI: 10.1016/J.Ijdevneu.2006.09.237  0.27
2015 Iejima D, Itabashi T, Kawamura Y, Noda T, Yuasa S, Fukuda K, Oka C, Iwata T. HTRA1 (high temperature requirement A serine peptidase 1) gene is transcriptionally regulated by insertion/deletion nucleotides located at the 3' end of the ARMS2 (age-related maculopathy susceptibility 2) gene in patients with age-related macular degeneration. The Journal of Biological Chemistry. 290: 2784-97. PMID 25519903 DOI: 10.1074/jbc.M114.593384  0.263
2006 Iwata T, Kennedy J, Thomson R. Mechanism of cerebral cortex malformation caused by the Fgfr3 mutations International Journal of Developmental Neuroscience. 24: 555. DOI: 10.1016/J.Ijdevneu.2006.09.199  0.248
2009 Moldrich R, Rankin A, Brookfield S, Goda S, Welsh L, Richards L, Iwata T. 12-P017 Fgfr3 regulates development of the caudal cerebral cortex Mechanisms of Development. 126. DOI: 10.1016/J.Mod.2009.06.471  0.244
2017 Iwata T, Pritchard J, Hurst C, Alahmari A, Fraser S, Orange C, Knowles M, Jones R, Leung H. Circulating tumour DNA-based monitoring of bladder cancer using targeted mutation approach European Journal of Surgical Oncology. 43: 2230-2231. DOI: 10.1016/J.Ejso.2017.10.160  0.238
2020 Pritchard JJG, Hamilton G, Hurst CD, Fraser S, Orange C, Knowles MA, Jones RJ, Leung HY, Iwata T. Monitoring of urothelial cancer disease status after treatment by digital droplet PCR liquid biopsy assays. Urologic Oncology. PMID 32532529 DOI: 10.1016/J.Urolonc.2020.05.012  0.236
2014 Yoshida T, Iwata T, Takai Y, Birchmeier W, Yamato M, Okano T. Afadin requirement for cytokine expressions in keratinocytes during chemically induced inflammation in mice. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 19: 842-52. PMID 25297509 DOI: 10.1111/Gtc.12184  0.23
2014 Xu G, Liu J, Yoshimoto K, Chen G, Iwata T, Mizusawa N, Duan Z, Wan C, Jiang J. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces expression of p27(kip¹) and FoxO3a in female rat cerebral cortex and PC12 cells. Toxicology Letters. 226: 294-302. PMID 24594276 DOI: 10.1016/j.toxlet.2014.02.019  0.229
2024 Iwata T, Kishikawa T, Seimiya T, Notoya G, Suzuki T, Shibata C, Miyakawa Y, Odawara N, Funato K, Tanaka E, Yamagami M, Sekiba K, Otsuka M, Koike K, Fujishiro M. Satellite double-stranded RNA induces mesenchymal transition in pancreatic cancer by regulating alternative splicing. The Journal of Biological Chemistry. 105742. PMID 38346537 DOI: 10.1016/j.jbc.2024.105742  0.211
2014 Batsaikhan BE, Yoshikawa K, Kurita N, Iwata T, Takasu C, Kashihara H, Shimada M. Cyclopamine decreased the expression of Sonic Hedgehog and its downstream genes in colon cancer stem cells. Anticancer Research. 34: 6339-44. PMID 25368233  0.21
2023 Sugahara S, Ishino Y, Sawada K, Iwata T, Shimanaka Y, Aoki J, Arai H, Kono N. Disease-related PSS1 mutant impedes the formation and function of osteoclasts. Journal of Lipid Research. 64: 100443. PMID 37714410 DOI: 10.1016/j.jlr.2023.100443  0.205
2014 Suphanantachat S, Iwata T, Ishihara J, Yamato M, Okano T, Izumi Y. A role for c-Kit in the maintenance of undifferentiated human mesenchymal stromal cells. Biomaterials. 35: 3618-26. PMID 24462355 DOI: 10.1016/j.biomaterials.2014.01.031  0.204
2021 Iwata T, Mizuno N, Ishida S, Kajiya M, Nagahara T, Kaneda-Ikeda E, Yoshioka M, Munenaga S, Ouhara K, Fujita T, Kawaguchi H, Kurihara H. Functional Regulatory Mechanisms Underlying Bone Marrow Mesenchymal Stem Cell Senescence During Cell Passages. Cell Biochemistry and Biophysics. PMID 33559812 DOI: 10.1007/s12013-021-00969-y  0.192
2014 Nishio H, Yaguchi T, Sugiyama J, Sumimoto H, Umezawa K, Iwata T, Susumu N, Fujii T, Kawamura N, Kobayashi A, Park J, Aoki D, Kawakami Y. Immunosuppression through constitutively activated NF-κB signalling in human ovarian cancer and its reversal by an NF-κB inhibitor. British Journal of Cancer. 110: 2965-74. PMID 24867687 DOI: 10.1038/bjc.2014.251  0.189
2017 Iwata T, Kuribayashi K, Nakasono M, Saito-Tarashima N, Minakawa N, Mizusawa N, Kido R, Yoshimoto K. The AMPK/mTOR pathway is involved in D-dopachrome tautomerase gene transcription in adipocytes differentiated from SGBS cells, a human preadipocyte cell line. Cytokine. 96: 195-202. PMID 28445821 DOI: 10.1016/j.cyto.2017.04.017  0.188
2015 Iwata T. Author Response: Postnatal Overexpression of the Human ARMS2 Gene Does Not Induce Abnormalities in Retina and Choroid in Transgenic Mouse Models. Investigative Ophthalmology & Visual Science. 56: 1389. PMID 25717154 DOI: 10.1167/iovs.14-16174  0.185
2014 Iwata T, Yamada S, Ito J, Inoshita N, Mizusawa N, Ono S, Yoshimoto K. A novel C-terminal nonsense mutation, Q315X, of the aryl hydrocarbon receptor-interacting protein gene in a Japanese familial isolated pituitary adenoma family. Endocrine Pathology. 25: 273-81. PMID 24789813 DOI: 10.1007/s12022-014-9318-7  0.184
2016 Minegishi Y, Nakayama M, Iejima D, Kawase K, Iwata T. Significance of optineurin mutations in glaucoma and other diseases. Progress in Retinal and Eye Research. PMID 27693724 DOI: 10.1016/j.preteyeres.2016.08.002  0.184
2010 Pellicano F, Thomson RE, Inman GJ, Iwata T. Regulation of cell proliferation and apoptosis in neuroblastoma cells by ccp1, a FGF2 downstream gene. Bmc Cancer. 10: 657. PMID 21118521 DOI: 10.1186/1471-2407-10-657  0.182
2010 Pellicano F, Thomson RE, Inman GJ, Iwata T. Regulation of cell proliferation and apoptosis in neuroblastoma cells by ccp1, a FGF2 downstream gene. Bmc Cancer. 10: 657. PMID 21118521 DOI: 10.1186/1471-2407-10-657  0.182
2006 Sumimoto H, Imabayashi F, Iwata T, Kawakami Y. The BRAF-MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells Journal of Experimental Medicine. 203: 1651-1656. PMID 16801397 DOI: 10.1084/jem.20051848  0.18
2014 Kimura O, Kondo Y, Kogure T, Kakazu E, Ninomiya M, Iwata T, Morosawa T, Shimosegawa T. Expression of EpCAM increases in the hepatitis B related and the treatment-resistant hepatocellular carcinoma. Biomed Research International. 2014: 172913. PMID 24696843 DOI: 10.1155/2014/172913  0.179
2014 Batsaikhan BE, Kurita N, Iwata T, Sato H, Yoshikawa K, Takasu C, Kashihara H, Matsumoto N, Ishibashi H, Shimada M. The role of activation-induced cytidine deaminase expression in gastric adenocarcinoma. Anticancer Research. 34: 995-1000. PMID 24511045  0.178
2011 Rizki G, Iwata TN, Li J, Riedel CG, Picard CL, Jan M, Murphy CT, Lee SS. The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO. Plos Genetics. 7: e1002235. PMID 21909281 DOI: 10.1371/Journal.Pgen.1002235  0.178
2014 Batsaikhan BE, Yoshikawa K, Kurita N, Iwata T, Takasu C, Kashihara H, Shimada M. Expression of Stathmin1 in gastric adenocarcinoma. Anticancer Research. 34: 4217-21. PMID 25075050  0.178
2015 Fujita T, Yoshimoto T, Matsuda S, Kajiya M, Kittaka M, Imai H, Iwata T, Uchida Y, Shiba H, Kurihara H. Interleukin-8 induces DNA synthesis, migration and down-regulation of cleaved caspase-3 in cultured human gingival epithelial cells. Journal of Periodontal Research. 50: 479-85. PMID 25244101 DOI: 10.1111/jre.12230  0.177
2008 Li J, Ebata A, Dong Y, Rizki G, Iwata T, Lee SS. Caenorhabditis elegans HCF-1 functions in longevity maintenance as a DAF-16 regulator. Plos Biology. 6: e233. PMID 18828672 DOI: 10.1371/journal.pbio.0060233  0.176
2011 Jin ZB, Okamoto S, Osakada F, Homma K, Assawachananont J, Hirami Y, Iwata T, Takahashi M. Modeling retinal degeneration using patient-specific induced pluripotent stem cells. Plos One. 6: e17084. PMID 21347327 DOI: 10.1371/Journal.Pone.0017084  0.176
2013 Yamada A, Iwata T, Yamato M, Okano T, Izumi Y. Diverse functions of secreted frizzled-related proteins in the osteoblastogenesis of human multipotent mesenchymal stromal cells. Biomaterials. 34: 3270-8. PMID 23384792 DOI: 10.1016/j.biomaterials.2013.01.066  0.175
2016 Onizuka S, Iwata T, Park SJ, Nakai K, Yamato M, Okano T, Izumi Y. ZBTB16 as a Downstream Target Gene of Osterix Regulates Osteoblastogenesis of Human Multipotent Mesenchymal Stromal Cells. Journal of Cellular Biochemistry. PMID 27335174 DOI: 10.1002/jcb.25634  0.174
2007 Han L, Dias Figueiredo M, Berghorn KA, Iwata TN, Clark-Campbell PA, Welsh IC, Wang W, O'brien TP, Lin DM, Roberson MS. Analysis of the gene regulatory program induced by the homeobox transcription factor distal-less 3 in mouse placenta. Endocrinology. 148: 1246-54. PMID 17110422 DOI: 10.1210/En.2006-1356  0.17
2015 Iwata T, Tamanaha T, Koezuka R, Tochiya M, Makino H, Kishimoto I, Mizusawa N, Ono S, Inoshita N, Yamada S, Shimatsu A, Yoshimoto K. Germline deletion and a somatic mutation of the PRKAR1A gene in a Carney complex-related pituitary adenoma. European Journal of Endocrinology / European Federation of Endocrine Societies. 172: K5-10. PMID 25336503 DOI: 10.1530/EJE-14-0685  0.167
2015 Shimizu R, Kamei N, Adachi N, Hamanishi M, Kamei G, Mahmoud EE, Nakano T, Iwata T, Yamato M, Okano T, Ochi M. Repair mechanism of osteochondral defect promoted by bioengineered chondrocyte sheet. Tissue Engineering. Part A. 21: 1131-41. PMID 25396711 DOI: 10.1089/ten.TEA.2014.0310  0.167
2013 Minegishi Y, Iejima D, Kobayashi H, Chi ZL, Kawase K, Yamamoto T, Seki T, Yuasa S, Fukuda K, Iwata T. Enhanced optineurin E50K-TBK1 interaction evokes protein insolubility and initiates familial primary open-angle glaucoma. Human Molecular Genetics. 22: 3559-67. PMID 23669351 DOI: 10.1093/hmg/ddt210  0.166
2018 Fujisaka Y, Iwata T, Tamai K, Nakamura M, Mochizuki M, Shibuya R, Yamaguchi K, Shimosegawa T, Satoh K. Long non-coding RNA HOTAIR up-regulates chemokine (C-C motif) ligand 2 and promotes proliferation of macrophages and myeloid-derived suppressor cells in hepatocellular carcinoma cell lines. Oncology Letters. 15: 509-514. PMID 29387231 DOI: 10.3892/ol.2017.7322  0.166
2016 Minegishi Y, Sheng X, Yoshitake K, Sergeev Y, Iejima D, Shibagaki Y, Monma N, Ikeo K, Furuno M, Zhuang W, Liu Y, Rong W, Hattori S, Iwata T. CCT2 Mutations Evoke Leber Congenital Amaurosis due to Chaperone Complex Instability. Scientific Reports. 6: 33742. PMID 27645772 DOI: 10.1038/srep33742  0.166
2014 Recuenco FC, Kobayashi K, Ishiwa A, Enomoto-Rogers Y, Fundador NG, Sugi T, Takemae H, Iwanaga T, Murakoshi F, Gong H, Inomata A, Horimoto T, Iwata T, Kato K. Gellan sulfate inhibits Plasmodium falciparum growth and invasion of red blood cells in vitro. Scientific Reports. 4: 4723. PMID 24740150 DOI: 10.1038/srep04723  0.164
2014 Iida M, Banno K, Yanokura M, Nakamura K, Adachi M, Nogami Y, Umene K, Masuda K, Kisu I, Iwata T, Tanaka K, Aoki D. Candidate biomarkers for cervical cancer treatment: Potential for clinical practice (Review). Molecular and Clinical Oncology. 2: 647-655. PMID 25054026 DOI: 10.3892/mco.2014.324  0.164
1986 Watanabe T, Sherman M, Shafman T, Iwata T, Kufe D. Effects of ornithine decarboxylase inhibition on c-myc expression during murine erythroleukemia cell proliferation and differentiation. Journal of Cellular Physiology. 127: 480-4. PMID 3458709 DOI: 10.1002/jcp.1041270319  0.164
2021 Suzuki T, Kishikawa T, Sato T, Takeda N, Sugiura Y, Seimiya T, Sekiba K, Ohno M, Iwata T, Ishibashi R, Otsuka M, Koike K. Mutant KRAS drives metabolic reprogramming and autophagic flux in premalignant pancreatic cells. Cancer Gene Therapy. PMID 33833413 DOI: 10.1038/s41417-021-00326-4  0.162
2013 Miyagawa T, Fujita T, Ouhara K, Matsuda S, Kajiya M, Hayashida K, Imai H, Yoshimoto T, Iwata T, Shiba H, Abiko Y, Kurihara H. Irsogladine maleate regulates the inflammatory related genes in human gingival epithelial cells stimulated by Aggregatibacter actinomycetemcomitans. International Immunopharmacology. 15: 340-7. PMID 23306101 DOI: 10.1016/j.intimp.2012.12.011  0.161
2010 Wang H, Kawashima N, Iwata T, Xu J, Takahashi S, Sugiyama T, Suda H. Differentiation of odontoblasts is negatively regulated by MEPE via its C-terminal fragment. Biochemical and Biophysical Research Communications. 398: 406-12. PMID 20599717 DOI: 10.1016/j.bbrc.2010.06.085  0.16
2023 Terasawa K, Seike T, Sakamoto K, Ohtake K, Terada T, Iwata T, Watabe T, Yokoyama S, Hara-Yokoyama M. Site-specific photo-crosslinking/cleavage for protein-protein interface identification reveals oligomeric assembly of lysosomal-associated membrane protein type 2A in mammalian cells. Protein Science : a Publication of the Protein Society. e4823. PMID 37906694 DOI: 10.1002/pro.4823  0.159
2015 Kittaka M, Kajiya M, Shiba H, Takewaki M, Takeshita K, Khung R, Fujita T, Iwata T, Nguyen TQ, Ouhara K, Takeda K, Fujita T, Kurihara H. Clumps of a mesenchymal stromal cell/extracellular matrix complex can be a novel tissue engineering therapy for bone regeneration. Cytotherapy. 17: 860-73. PMID 25743634 DOI: 10.1016/j.jcyt.2015.01.007  0.158
2013 Tatsumi K, Ohashi K, Matsubara Y, Kohori A, Ohno T, Kakidachi H, Horii A, Kanegae K, Utoh R, Iwata T, Okano T. Tissue factor triggers procoagulation in transplanted mesenchymal stem cells leading to thromboembolism. Biochemical and Biophysical Research Communications. 431: 203-9. PMID 23313481 DOI: 10.1016/j.bbrc.2012.12.134  0.158
2023 Yoshii H, Kajiya M, Yoshino M, Morimoto S, Horikoshi S, Tari M, Motoike S, Iwata T, Ouhara K, Ando T, Yoshimoto T, Shintani T, Mizuno N. Mechanosignaling YAP/TAZ-TEAD Axis Regulates the Immunomodulatory Properties of Mesenchymal Stem Cells. Stem Cell Reviews and Reports. PMID 37917410 DOI: 10.1007/s12015-023-10646-7  0.158
2021 Pan Y, Iejima D, Nakayama M, Suga A, Noda T, Kaur I, Das T, Chakrabarti S, Guymer RH, DeAngelis MM, Yamamoto M, Baird PN, Iwata T. Binding of Gtf2i-β/δ transcription factors to the ARMS2 gene leads to increased circulating HTRA1 in AMD patients and in vitro. The Journal of Biological Chemistry. 100456. PMID 33636181 DOI: 10.1016/j.jbc.2021.100456  0.158
2019 Ramírez JA, Iwata T, Park H, Tsang M, Kang J, Cui K, Kwong W, James RG, Baba M, Schmidt LS, Iritani BM. Folliculin Interacting Protein 1 Maintains Metabolic Homeostasis during B Cell Development by Modulating AMPK, mTORC1, and TFE3. Journal of Immunology (Baltimore, Md. : 1950). PMID 31676673 DOI: 10.4049/jimmunol.1900395  0.157
2015 Iwawaki Y, Mizusawa N, Iwata T, Higaki N, Goto T, Watanabe M, Tomotake Y, Ichikawa T, Yoshimoto K. MiR-494-3p induced by compressive force inhibits cell proliferation in MC3T3-E1 cells. Journal of Bioscience and Bioengineering. PMID 25795570 DOI: 10.1016/j.jbiosc.2015.02.006  0.157
2023 Sugi T, Katoh Y, Ikeda T, Seta D, Iwata T, Nishio H, Sugawara M, Kato D, Katoh K, Kawana K, Yaguchi T, Kawakami Y, Hirai S. SCD1 inhibition enhances the effector functions of CD8 T cells via ACAT1-dependent reduction of esterified cholesterol. Cancer Science. PMID 37879607 DOI: 10.1111/cas.15999  0.156
2014 Matsumoto N, Yoshikawa K, Shimada M, Kurita N, Sato H, Iwata T, Higashijima J, Chikakiyo M, Nishi M, Kashihara H, Takasu C, Eto S, Takahashi A, Akutagawa M, Emoto T. Effect of light irradiation by light emitting diode on colon cancer cells. Anticancer Research. 34: 4709-16. PMID 25202048  0.156
2022 Takada K, Chiba T, Miyazaki T, Yagasaki L, Nakamichi R, Iwata T, Moriyama K, Harada H, Asahara H. Single Cell RNA Sequencing Reveals Critical Functions of in Periodontal Ligament Homeostasis. Frontiers in Cell and Developmental Biology. 10: 795441. PMID 35186919 DOI: 10.3389/fcell.2022.795441  0.155
2011 Shen X, Ying H, Qiu Y, Park JS, Shyam R, Chi ZL, Iwata T, Yue BY. Processing of optineurin in neuronal cells. The Journal of Biological Chemistry. 286: 3618-29. PMID 21059646 DOI: 10.1074/Jbc.M110.175810  0.153
2012 Pellakuru LG, Iwata T, Gurel B, Schultz D, Hicks J, Bethel C, Yegnasubramanian S, De Marzo AM. Global levels of H3K27me3 track with differentiation in vivo and are deregulated by MYC in prostate cancer. The American Journal of Pathology. 181: 560-9. PMID 22713676 DOI: 10.1016/J.Ajpath.2012.04.021  0.153
2019 Tanaka E, Miyakawa Y, Kishikawa T, Seimiya T, Iwata T, Funato K, Odawara N, Sekiba K, Yamagami M, Suzuki T, Ishibashi R, Otsuka M, Koike K. Expression of circular RNA CDR1‑AS in colon cancer cells increases cell surface PD‑L1 protein levels. Oncology Reports. PMID 31322270 DOI: 10.3892/or.2019.7244  0.153
2017 Iwata TN, Ramírez-Komo JA, Park H, Iritani BM. Control of B lymphocyte development and functions by the mTOR signaling pathways. Cytokine & Growth Factor Reviews. PMID 28583723 DOI: 10.1016/j.cytogfr.2017.04.005  0.151
2013 Ito K, Kobayashi M, Kuroki S, Sasaki Y, Iwata T, Mori K, Kuroki T, Ozawa Y, Tetsuka M, Nakagawa T, Hiroi T, Yamamoto H, Ono K, Washizu T, Bonkobara M. The proteasome inhibitor bortezomib inhibits the growth of canine malignant melanoma cells in vitro and in vivo. Veterinary Journal (London, England : 1997). 198: 577-82. PMID 24035468 DOI: 10.1016/j.tvjl.2013.08.003  0.151
2018 Seimiya T, Otsuka M, Iwata T, Tanaka E, Suzuki T, Sekiba K, Yamagami M, Ishibashi R, Koike K. Inflammation and de-differentiation in pancreatic carcinogenesis. World Journal of Clinical Cases. 6: 882-891. PMID 30568942 DOI: 10.12998/wjcc.v6.i15.882  0.15
2006 Yamasaki H, Sada A, Iwata T, Niwa T, Tomizawa M, Xanthopoulos KG, Koike T, Shiojiri N. Suppression of C/EBPalpha expression in periportal hepatoblasts may stimulate biliary cell differentiation through increased Hnf6 and Hnf1b expression. Development (Cambridge, England). 133: 4233-43. PMID 17021047 DOI: 10.1242/dev.02591  0.15
2011 Wang HG, Kawashima N, Iwata T, Xu J, Takahashi S, Sugiyama T, Suda H. MEPE activated by furin promotes pulpal cell adhesion. Journal of Dental Research. 90: 529-34. PMID 21248358 DOI: 10.1177/0022034510391057  0.15
2012 Okabayashi K, Fujita T, Miyazaki J, Okada T, Iwata T, Hirao N, Noji S, Tsukamoto N, Goshima N, Hasegawa H, Takeuchi H, Ueda M, Kitagawa Y, Kawakami Y. Cancer-testis antigen BORIS is a novel prognostic marker for patients with esophageal cancer. Cancer Science. 103: 1617-24. PMID 22676270 DOI: 10.1111/j.1349-7006.2012.02355.x  0.149
2009 Umemori M, Habara O, Iwata T, Maeda K, Nishinoue K, Okabe A, Takemura M, Takahashi K, Saigo K, Ueda R, Adachi-Yamada T. RNAi-mediated knockdown showing impaired cell survival in Drosophila wing imaginal disc. Gene Regulation and Systems Biology. 3: 11-20. PMID 19838331 DOI: 10.4137/grsb.s2100  0.149
2019 Maekawa S, Onizuka S, Katagiri S, Hatasa M, Ohsugi Y, Sasaki N, Watanabe K, Ohtsu A, Komazaki R, Ogura K, Miyoshi-Akiyama T, Iwata T, Nitta H, Izumi Y. RNA sequencing for ligature induced periodontitis in mice revealed important role of S100A8 and S100A9 for periodontal destruction. Scientific Reports. 9: 14663. PMID 31605018 DOI: 10.1038/s41598-019-50959-7  0.148
2017 Iwata T, Uchino T, Koyama A, Johmura Y, Koyama K, Saito T, Ishiguro S, Arikawa T, Komatsu S, Miyachi M, Sano T, Nakanishi M, Shimada M. The G2 checkpoint inhibitor CBP-93872 increases the sensitivity of colorectal and pancreatic cancer cells to chemotherapy. Plos One. 12: e0178221. PMID 28558031 DOI: 10.1371/journal.pone.0178221  0.148
2018 Kawamura Y, Suga A, Fujimaki T, Yoshitake K, Tsunoda K, Murakami A, Iwata T. LRRTM4-C538Y novel gene mutation is associated with hereditary macular degeneration with novel dysfunction of ON-type bipolar cells. Journal of Human Genetics. PMID 29760528 DOI: 10.1038/s10038-018-0465-4  0.148
2018 Tentaku A, Shimohata T, Hatayama S, Kido J, Nguyen AQ, Kanda Y, Fukushima S, Uebanso T, Iwata T, Mawatari K, Harada N, Takahashi A. Host cellular unfolded protein response signaling regulates Campylobacter jejuni invasion. Plos One. 13: e0205865. PMID 30321237 DOI: 10.1371/journal.pone.0205865  0.148
2024 Pan Y, Iwata T. Molecular genetics of inherited normal tension glaucoma. Indian Journal of Ophthalmology. PMID 38389252 DOI: 10.4103/IJO.IJO_3204_23  0.147
2009 Yagi M, Kantarci A, Iwata T, Omori K, Ayilavarapu S, Ito K, Hasturk H, Van Dyke TE. PDK1 regulates chemotaxis in human neutrophils. Journal of Dental Research. 88: 1119-24. PMID 19892919 DOI: 10.1177/0022034509349402  0.147
2007 Iwata T, Mizusawa N, Taketani Y, Itakura M, Yoshimoto K. Parafibromin tumor suppressor enhances cell growth in the cells expressing SV40 large T antigen. Oncogene. 26: 6176-83. PMID 17404568 DOI: 10.1038/sj.onc.1210445  0.145
2005 Nishimura K, Yamashita K, Kato Y, Iwata T, Iwata K, Nishikawa T, Goto S, Hayakawa T. Inhibitory activity on matrix metalloproteinases and cell-proliferating activity of tissue inhibitor of metalloproteinases-1 (TIMP-1)-contrastive difference between human and bovine TIMP-1s on mouse cell proliferation. Growth Factors (Chur, Switzerland). 23: 135-42. PMID 16019435 DOI: 10.1080/08977190500138772  0.144
2014 Pirraco RP, Iwata T, Yoshida T, Marques AP, Yamato M, Reis RL, Okano T. Endothelial cells enhance the in vivo bone-forming ability of osteogenic cell sheets. Laboratory Investigation; a Journal of Technical Methods and Pathology. 94: 663-73. PMID 24709778 DOI: 10.1038/Labinvest.2014.55  0.144
1999 Wang Y, He H, Zigler JS, Iwata T, Ibaraki N, Reddy VN, Carper D. bFGF suppresses serum-deprivation-induced apoptosis in a human lens epithelial cell line. Experimental Cell Research. 249: 123-30. PMID 10328960 DOI: 10.1006/EXCR.1999.4450  0.144
2013 Iwata TN, Cowley TJ, Sloma M, Ji Y, Kim H, Qi L, Lee SS. The transcriptional co-regulator HCF-1 is required for INS-1 β-cell glucose-stimulated insulin secretion. Plos One. 8: e78841. PMID 24250814 DOI: 10.1371/Journal.Pone.0078841  0.144
2007 Iwata T, Yamakoshi Y, Simmer JP, Ishikawa I, Hu JC. Establishment of porcine pulp-derived cell lines and expression of recombinant dentin sialoprotein and recombinant dentin matrix protein-1. European Journal of Oral Sciences. 115: 48-56. PMID 17305716 DOI: 10.1111/j.1600-0722.2007.00426.x  0.143
2006 Iwata T, Sumimoto H, Mizuguchi H, Kawakami Y. 422. Enhancement of Human Monocyte-Derived Dendritic Cell Functions by Adenovirus- Mediated RNA Interference of STAT-3 Molecular Therapy. 13: S162. DOI: 10.1016/j.ymthe.2006.08.487  0.142
2012 Miyatani T, Kurita N, Utsunomiya T, Iwata T, Nishioka M, Yoshikawa K, Higashijima J, Kashihara H, Takasu C, Fukushima M, Shimada M. Platelet-derived endothelial cell growth factor/thymidine phosphorylase inhibitor augments radiotherapeutic efficacy in experimental colorectal cancer. Cancer Letters. 318: 199-205. PMID 22178656 DOI: 10.1016/j.canlet.2011.12.010  0.141
2016 Iwata TN, Ramírez JA, Tsang M, Park H, Margineantu DH, Hockenbery DM, Iritani BM. Conditional Disruption of Raptor Reveals an Essential Role for mTORC1 in B Cell Development, Survival, and Metabolism. Journal of Immunology (Baltimore, Md. : 1950). PMID 27521345 DOI: 10.4049/Jimmunol.1600492  0.141
2015 Kashihara H, Shimada M, Kurita N, Iwata T, Sato H, Yoshikawa K, Miyatani T, Takasu C, Matsumoto N. Protein kinase Cι is a new prognostic factor in gastric cancer. Surgery Today. 45: 759-64. PMID 25108825 DOI: 10.1007/s00595-014-1010-5  0.141
2018 Centini R, Tsang M, Iwata T, Park H, Delrow J, Margineantu D, Iritani BM, Gu H, Liggitt HD, Kang J, Kang L, Hockenbery DM, Raftery D, Iritani BM. Loss of Fnip1 alters kidney developmental transcriptional program and synergizes with TSC1 loss to promote mTORC1 activation and renal cyst formation. Plos One. 13: e0197973. PMID 29897930 DOI: 10.1371/Journal.Pone.0197973  0.141
2009 Hossain MG, Iwata T, Mizusawa N, Shima SW, Okutsu T, Ishimoto K, Yoshimoto K. Compressive force inhibits adipogenesis through COX-2-mediated down-regulation of PPARgamma2 and C/EBPalpha. Journal of Bioscience and Bioengineering. 109: 297-303. PMID 20159581 DOI: 10.1016/j.jbiosc.2009.09.003  0.14
2012 Inoue Y, Saigusa S, Iwata T, Okugawa Y, Toiyama Y, Tanaka K, Uchida K, Mohri Y, Kusunoki M. The prognostic value of KRAS mutations in patients with colorectal cancer. Oncology Reports. 28: 1579-84. PMID 22922794 DOI: 10.3892/or.2012.1974  0.14
2021 Hirai I, Funakoshi T, Kamijuku H, Fukuda K, Mori M, Sakurai M, Koda Y, Kato J, Mori T, Watanabe N, Noji S, Yaguchi T, Iwata T, Ohta S, Fujita T, et al. Adoptive cell therapy using tumor-infiltrating lymphocytes for melanoma refractory to immune-checkpoint inhibitors. Cancer Science. PMID 34101300 DOI: 10.1111/cas.15009  0.14
2019 Hirao N, Iwata T, Tanaka K, Nishio H, Nakamura M, Morisada T, Morii K, Maruyama N, Katoh Y, Yaguchi T, Ohta S, Kukimoto I, Aoki D, Kawakami Y. Transcription factor homeobox D9 is involved in the malignant phenotype of cervical cancer through direct binding to the human papillomavirus oncogene promoter. Gynecologic Oncology. PMID 31477279 DOI: 10.1016/j.ygyno.2019.08.026  0.139
2020 Kaneda-Ikeda E, Iwata T, Mizuno N, Nagahara T, Kajiya M, Ouhara K, Yoshioka M, Ishida S, Kawaguchi H, Kurihara H. Regulation of osteogenesis via miR-101-3p in mesenchymal stem cells by human gingival fibroblasts. Journal of Bone and Mineral Metabolism. PMID 31970478 DOI: 10.1007/s00774-019-01080-2  0.139
2021 Takahashi A, Iwata T, Yamashita K. Knockdown of D-dopachrome Tautomerase Inhibits Cell Proliferation in Human HepG2 Cell Line. Anticancer Research. 41: 4077-4082. PMID 34281877 DOI: 10.21873/anticanres.15209  0.139
2013 Yoshida T, Iwata T, Umemoto T, Shiratsuchi Y, Kawashima N, Sugiyama T, Yamato M, Okano T. Promotion of mouse ameloblast proliferation by Lgr5 mediated integrin signaling. Journal of Cellular Biochemistry. 114: 2138-47. PMID 23553959 DOI: 10.1002/jcb.24564  0.138
2020 Kaneda-Ikeda E, Iwata T, Mizuno N, Nagahara T, Kajiya M, Takeda K, Hirata R, Ishida S, Yoshioka M, Fujita T, Kawaguchi H, Kurihara H. Periodontal ligament cells regulate osteogenesis via miR-299-5p in mesenchymal stem cells. Differentiation; Research in Biological Diversity. 112: 47-57. PMID 31951879 DOI: 10.1016/j.diff.2020.01.001  0.138
2020 Kobayashi T, Torii D, Iwata T, Izumi Y, Nasu M, Tsutsui TW. Characterization of proliferation, differentiation potential, and gene expression among clonal cultures of human dental pulp cells. Human Cell. PMID 32180208 DOI: 10.1007/s13577-020-00327-9  0.137
2019 Sjöqvist S, Ishikawa T, Shimura D, Kasai Y, Imafuku A, Bou-Ghannam S, Iwata T, Kanai N. Exosomes derived from clinical-grade oral mucosal epithelial cell sheets promote wound healing. Journal of Extracellular Vesicles. 8: 1565264. PMID 30719240 DOI: 10.1080/20013078.2019.1565264  0.137
2020 Mizuno N, Iwata T, Ohsawa R, Ouhara K, Matsuda S, Kajiya M, Matsuda Y, Kume K, Tada Y, Morino H, Yoshimoto T, Ueki Y, Mihara K, Sotomaru Y, Takeda K, et al. Optineurin regulates osteoblastogenesis through STAT1. Biochemical and Biophysical Research Communications. PMID 32171527 DOI: 10.1016/j.bbrc.2020.03.028  0.137
2005 Ishii M, Koike C, Igarashi A, Yamanaka K, Pan H, Higashi Y, Kawaguchi H, Sugiyama M, Kamata N, Iwata T, Matsubara T, Nakamura K, Kurihara H, Tsuji K, Kato Y. Molecular markers distinguish bone marrow mesenchymal stem cells from fibroblasts Biochemical and Biophysical Research Communications. 332: 297-303. PMID 15896330 DOI: 10.1016/j.bbrc.2005.04.118  0.137
2019 Sjoqvist S, Kasai Y, Shimura D, Ishikawa T, Ali N, Iwata T, Kanai N. Oral keratinocyte-derived exosomes regulate proliferation of fibroblasts and epithelial cells. Biochemical and Biophysical Research Communications. PMID 31078263 DOI: 10.1016/j.bbrc.2019.04.202  0.136
2015 Iejima D, Nakayama M, Iwata T. HTRA1 Overexpression Induces the Exudative Form of Age-related Macular Degeneration. Journal of Stem Cells. 10: 193-203. PMID 27125063  0.136
2007 Shibuya M, Okamoto H, Nozawa T, Utsumi J, Reddy VN, Echizen H, Tanaka Y, Iwata T. Proteomic and transcriptomic analyses of retinal pigment epithelial cells exposed to REF-1/TFPI-2. Investigative Ophthalmology & Visual Science. 48: 516-21. PMID 17251444 DOI: 10.1167/iovs.06-0434  0.136
2014 Xu G, Li Y, Yoshimoto K, Wu Q, Chen G, Iwata T, Mizusawa N, Wan C, Nie X. 2,3,7,8-Tetrachlorodibenzo-p-dioxin stimulates proliferation of HAPI microglia by affecting the Akt/GSK-3β/cyclin D1 signaling pathway. Toxicology Letters. 224: 362-70. PMID 24231000 DOI: 10.1016/j.toxlet.2013.11.003  0.136
2004 Kawamoto T, Noshiro M, Sato F, Maemura K, Takeda N, Nagai R, Iwata T, Fujimoto K, Furukawa M, Miyazaki K, Honma S, Honma Ki, Kato Y. A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation. Biochemical and Biophysical Research Communications. 313: 117-24. PMID 14672706 DOI: 10.1016/j.bbrc.2003.11.099  0.135
2023 Hirata R, Iwata T, Fujita T, Nagahara T, Matsuda S, Sasaki S, Taniguchi Y, Hamamoto Y, Ouhara K, Kudo Y, Kurihara H, Mizuno N. Periostin regulates integrin expression in gingival epithelial cells. Journal of Oral Biosciences. PMID 38048847 DOI: 10.1016/j.job.2023.11.009  0.135
2020 Tsuchiya Y, Hayashi M, Nagamatsu K, Ono T, Kamakura M, Iwata T, Nakashima T. The key royal jelly component 10-hydroxy-2-decenoic acid protects against bone loss by inhibiting NF-κB signaling downstream of FFAR4. The Journal of Biological Chemistry. PMID 32647011 DOI: 10.1074/jbc.RA120.013821  0.135
1994 Mukaida H, Hirabayashi N, Hirai T, Yamashita Y, Iwata T, Saeki S, Toge T. The inhibitory effect caused by suramin on the paracrine growth of human cancer cells and fibroblasts. Surgery Today. 24: 234-40. PMID 8003867 DOI: 10.1007/BF02032894  0.135
2015 Maeda E, Iwata T, Murata K. Effects of work stress and home stress on autonomic nervous function in Japanese male workers. Industrial Health. 53: 132-8. PMID 25382383 DOI: DN/JST.JSTAGE/indhealth/2014-0157  0.135
2004 Koga T, Inui M, Inoue K, Kim S, Suematsu A, Kobayashi E, Iwata T, Ohnishi H, Matozaki T, Kodama T, Taniguchi T, Takayanagi H, Takai T. Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis. Nature. 428: 758-63. PMID 15085135 DOI: 10.1038/nature02444  0.134
2005 Shiojiri N, Takeshita K, Yamasaki H, Iwata T. Suppression of C/EBP alpha expression in biliary cell differentiation from hepatoblasts during mouse liver development. Journal of Hepatology. 41: 790-8. PMID 15519652 DOI: 10.1016/j.jhep.2004.07.011  0.134
2016 Biswas P, Chavali VR, Agnello G, Stone E, Chakarova C, Duncan JL, Kannabiran C, Homsher M, Bhattacharya SS, Naeem MA, Kimchi A, Sharon D, Iwata T, Riazuddin S, Reddy GB, et al. A missense mutation in the ASRGL1 gene is involved in causing autosomal recessive retinal degeneration. Human Molecular Genetics. PMID 27106100 DOI: 10.1093/Hmg/Ddw113  0.134
2012 Kabuto T, Takahashi H, Goto-Fukuura Y, Igarashi T, Akahori M, Kameya S, Iwata T, Mizota A, Yamaki K, Miyake Y, Takahashi H. A new mutation in the RP1L1 gene in a patient with occult macular dystrophy associated with a depolarizing pattern of focal macular electroretinograms. Molecular Vision. 18: 1031-9. PMID 22605915  0.132
2012 Ishimoto K, Iwata T, Taniguchi H, Mizusawa N, Tanaka E, Yoshimoto K. D-dopachrome tautomerase promotes IL-6 expression and inhibits adipogenesis in preadipocytes. Cytokine. 60: 772-7. PMID 22951300 DOI: 10.1016/j.cyto.2012.07.037  0.132
2020 Iwata T, Sadahira T, Ochiai K, Ueki H, Sasaki T, Haung P, Araki M, Watanabe T, Nasu Y, Watanabe M. Tumor suppressor REIC/Dkk-3 and its interacting protein SGTA inhibit glucocorticoid receptor to nuclear transport. Experimental and Therapeutic Medicine. 20: 1739-1745. PMID 32765682 DOI: 10.3892/etm.2020.8819  0.132
2020 Oda-Kawashima K, Sedukhina AS, Okamoto N, Lytvyn M, Minagawa K, Iwata T, Kumai T, Sato E, Inada E, Yamaura A, Sakamoto M, Roche-Molina M, Bernal JA, Sato K. NF-kB signaling in cardiomyocytes is inhibited by sevoflurane and promoted by propofol. Febs Open Bio. PMID 31898867 DOI: 10.1002/2211-5463.12783  0.132
2018 Inagaki S, Kawase K, Funato M, Seki J, Kawase C, Ohuchi K, Kameyama T, Ando S, Sato A, Morozumi W, Nakamura S, Shimazawa M, Iejima D, Iwata T, Yamamoto T, et al. Effect of Timolol on Optineurin Aggregation in Transformed Induced Pluripotent Stem Cells Derived From Patient With Familial Glaucoma. Investigative Ophthalmology & Visual Science. 59: 2293-2304. PMID 29847634 DOI: 10.1167/iovs.17-22975  0.132
1998 McGowan MH, Iwata T, Carper DA. Characterization of the mouse aldose reductase gene and promoter in a lens epithelial cell line. Molecular Vision. 4: 2. PMID 9485485  0.131
1991 Iwata T, Vaughn J, Frohlich ED, Cole FE. Phorbol and calcium decreased atriopeptin response in a human renal cell line. Peptides. 12: 301-7. PMID 1648714 DOI: 10.1016/0196-9781(91)90016-i  0.131
2018 Katagiri S, Hayashi T, Yoshitake K, Murai N, Matsui Z, Kubo H, Satoh H, Matsufuji S, Takamura T, Yokoo T, Omori Y, Furukawa T, Iwata T, Nakano T. Compound heterozygous splice site variants in the SCLT1 gene highlight an additional candidate locus for Senior-Løken syndrome. Scientific Reports. 8: 16733. PMID 30425282 DOI: 10.1038/s41598-018-35152-6  0.131
1982 Incefy GS, O'Reilly RJ, Kapoor N, Iwata T, Good RA. In vitro differentiation of human marrow T cell precursors by thymic factors in severe combined immunodeficiency. Transplantation. 32: 299-305. PMID 6977211 DOI: 10.1097/00007890-198110000-00008  0.131
2018 Muraoka Y, Iida Y, Ikeda HO, Iwai S, Hata M, Iwata T, Nakayama M, Shimozawa N, Katakai Y, Kakizuka A, Yoshimura N, Tsujikawa A. KUS121, an ATP regulator, mitigates chorioretinal pathologies in animal models of age-related macular degeneration. Heliyon. 4: e00624. PMID 29872758 DOI: 10.1016/j.heliyon.2018.e00624  0.131
2020 Mizuno N, Kume K, Nagatani Y, Matsuda S, Iwata T, Ouhara K, Kajiya M, Takeda K, Matsuda Y, Tada Y, Ohsawa R, Morino H, Mihara K, Fujita T, Kawaguchi H, et al. Aggressive periodontitis and NOD2 variants. Journal of Human Genetics. PMID 32424308 DOI: 10.1038/s10038-020-0777-z  0.131
2001 Abe K, Namikawa K, Honma M, Iwata T, Matsuoka I, Watabe K, Kiyama H. Inhibition of Ras extracellular-signal-regulated kinase (ERK) mediated signaling promotes ciliary neurotrophic factor (CNTF) expression in Schwann cells. Journal of Neurochemistry. 77: 700-3. PMID 11299332 DOI: 10.1046/J.1471-4159.2001.00286.X  0.13
2004 Tanaka Y, Utsumi J, Matsui M, Sudo T, Nakamura N, Mutoh M, Kajita A, Sone S, Kigasawa K, Shibuya M, Reddy VN, Zhang Q, Iwata T. Purification, molecular cloning, and expression of a novel growth-promoting factor for retinal pigment epithelial cells, REF-1/TFPI-2. Investigative Ophthalmology & Visual Science. 45: 245-52. PMID 14691180  0.13
2012 Iwata T, Taniguchi H, Kuwajima M, Taniguchi T, Okuda Y, Sukeno A, Ishimoto K, Mizusawa N, Yoshimoto K. The action of D-dopachrome tautomerase as an adipokine in adipocyte lipid metabolism. Plos One. 7: e33402. PMID 22428043 DOI: 10.1371/journal.pone.0033402  0.129
2020 Komatsu N, Kajiya M, Morimoto S, Motoike S, Yoshii H, Iwata T, Ouhara K, Matsuda S, Mizuno N, Kurihara H. Cox2-mediated PGE2 production via p38/JNK-c-fos signaling inhibits cell apoptosis in 3D floating culture clumps of mesenchymal stem cell/extracellular matrix complexes. Biochemical and Biophysical Research Communications. PMID 32553627 DOI: 10.1016/j.bbrc.2020.05.100  0.129
2010 Iwata T, Schultz D, Hicks J, Hubbard GK, Mutton LN, Lotan TL, Bethel C, Lotz MT, Yegnasubramanian S, Nelson WG, Dang CV, Xu M, Anele U, Koh CM, Bieberich CJ, et al. MYC overexpression induces prostatic intraepithelial neoplasia and loss of Nkx3.1 in mouse luminal epithelial cells. Plos One. 5: e9427. PMID 20195545 DOI: 10.1371/Journal.Pone.0009427  0.128
2006 Iwata T, Kawamoto T, Sasabe E, Miyazaki K, Fujimoto K, Noshiro M, Kurihara H, Kato Y. Effects of overexpression of basic helix-loop-helix transcription factor Dec1 on osteogenic and adipogenic differentiation of mesenchymal stem cells. European Journal of Cell Biology. 85: 423-31. PMID 16487626 DOI: 10.1016/j.ejcb.2005.12.007  0.128
2015 Kuniyoshi K, Ikeo K, Sakuramoto H, Furuno M, Yoshitake K, Hatsukawa Y, Nakao A, Tsunoda K, Kusaka S, Shimomura Y, Iwata T. Novel nonsense and splice site mutations in CRB1 gene in two Japanese patients with early-onset retinal dystrophy. Documenta Ophthalmologica. Advances in Ophthalmology. 130: 49-55. PMID 25323024 DOI: 10.1007/s10633-014-9464-8  0.128
2015 Ohmura G, Tsujikawa T, Yaguchi T, Kawamura N, Mikami S, Sugiyama J, Nakamura K, Kobayashi A, Iwata T, Nakano H, Shimada T, Hisa Y, Kawakami Y. Aberrant Myosin 1b Expression Promotes Cell Migration and Lymph Node Metastasis of HNSCC. Molecular Cancer Research : McR. 13: 721-31. PMID 25421751 DOI: 10.1158/1541-7786.MCR-14-0410  0.128
2014 Katagiri S, Hayashi T, Akahori M, Itabashi T, Nishino J, Yoshitake K, Furuno M, Ikeo K, Okada T, Tsuneoka H, Iwata T. RHO Mutations (p.W126L and p.A346P) in Two Japanese Families with Autosomal Dominant Retinitis Pigmentosa. Journal of Ophthalmology. 2014: 210947. PMID 25485142 DOI: 10.1155/2014/210947  0.127
2019 Kondo H, Oku K, Katagiri S, Hayashi T, Nakano T, Iwata A, Kuniyoshi K, Kusaka S, Hiyoshi A, Uchio E, Kondo M, Oishi N, Kameya S, Mizota A, Naoi N, ... ... Iwata T, et al. Novel mutations in the gene in Japanese patients with X-linked congenital retinoschisis. Human Genome Variation. 6: 3. PMID 30652005 DOI: 10.1038/s41439-018-0034-6  0.127
2020 Iwata T, Mizuno N, Nagahara T, Kaneda-Ikeda E, Kajiya M, Kitagawa M, Takeda K, Yoshioka M, Yagi R, Takata T, Kurihara H. Identification of regulatory mRNA and microRNA for differentiation into cementoblasts and periodontal ligament cells. Journal of Periodontal Research. PMID 32797637 DOI: 10.1111/jre.12794  0.126
2023 Yasuda N, Ikeo S, Sokai A, Sakai Y, Hayashi Y, Kitano S, Itoi N, Lee T, Iwata T, Nishimura T. Concurrent trastuzumab deruxtecan-induced interstitial lung disease and COVID-19 in the treatment of advanced breast cancer. Oxford Medical Case Reports. 2023: omad135. PMID 38145267 DOI: 10.1093/omcr/omad135  0.126
2022 Katoh Y, Yaguchi T, Kubo A, Iwata T, Morii K, Kato D, Ohta S, Satomi R, Yamamoto Y, Oyamada Y, Ouchi K, Takahashi S, Ishioka C, Matoba R, Suematsu M, et al. Inhibition of stearoyl-CoA desaturase 1 (SCD1) enhances the antitumor T cell response through regulating β-catenin signaling in cancer cells and ER stress in T cells and synergizes with anti-PD-1 antibody. Journal For Immunotherapy of Cancer. 10. PMID 35793868 DOI: 10.1136/jitc-2022-004616  0.126
2023 Matsushita I, Izumi H, Ueno S, Hayashi T, Fujinami K, Tsunoda K, Iwata T, Kiuchi Y, Kondo H. Functional Characteristics of Diverse Mutations Associated with Isolated Foveal Hypoplasia. Genes. 14. PMID 37510387 DOI: 10.3390/genes14071483  0.126
2023 Lin P, Niimi H, Hirota T, Ohsugi Y, Shimohira T, Toyoshima K, Katagiri S, Iwata T, Aoki A. Effects of low-level Er:YAG laser irradiation on proliferation and gene expression in primary gingival fibroblasts isolated from mouse maxilla. Journal of Biophotonics. e202300166. PMID 37975254 DOI: 10.1002/jbio.202300166  0.125
2011 Iwata T, Sugio K, Uramoto H, Yamada S, Onitsuka T, Nose N, Ono K, Takenoyama M, Oyama T, Hanagiri T, Yasumoto K. Detection of EGFR and K-ras mutations for diagnosis of multiple lung adenocarcinomas. Frontiers in Bioscience (Landmark Edition). 16: 2961-9. PMID 21622214  0.125
2011 Enomoto T, Ohmoto M, Iwata T, Uno A, Saitou M, Yamaguchi T, Kominami R, Matsumoto I, Hirota J. Bcl11b/Ctip2 controls the differentiation of vomeronasal sensory neurons in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10159-73. PMID 21752992 DOI: 10.1523/JNEUROSCI.1245-11.2011  0.125
1998 Iwata T, Minucci S, McGowan M, Carper D. Identification of a novel cis-element required for the constitutive activity and osmotic response of the rat aldose reductase promoter. The Journal of Biological Chemistry. 272: 32500-6. PMID 9405461 DOI: 10.1074/jbc.272.51.32500  0.125
1999 Sudesh K, Fukui T, Taguchi K, Iwata T, Doi Y. Improved production of poly(4-hydroxybutyrate) by Comamonas acidovorans and its freeze-fracture morphology. International Journal of Biological Macromolecules. 25: 79-85. PMID 10416653 DOI: 10.1016/s0141-8130(99)00018-5  0.125
1996 Mazuruk K, Schoen TJ, Chader GJ, Iwata T, Rodriguez IR. Structural organization and chromosomal localization of the human ribosomal protein L9 gene. Biochimica Et Biophysica Acta. 1305: 151-62. PMID 8597601  0.124
2013 Xu G, Li Y, Yoshimoto K, Chen G, Wan C, Iwata T, Mizusawa N, Duan Z, Liu J, Jiang J. 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced inflammatory activation is mediated by intracellular free calcium in microglial cells. Toxicology. 308: 158-67. PMID 23583884 DOI: 10.1016/j.tox.2013.04.002  0.124
2004 Zhang Q, Mashima Y, Noda S, Imamura Y, Kudoh J, Shimizu N, Nishiyama T, Umeda S, Oguchi Y, Tanaka Y, Iwata T. Characterization of AOC2 gene encoding a copper-binding amine oxidase expressed specifically in retina. Gene. 318: 45-53. PMID 14585497 DOI: 10.1016/s0378-1119(03)00753-4  0.124
2021 Hata A, Nakajima T, Matsusaka K, Fukuyo M, Nakayama M, Morimoto J, Ito Y, Yamamoto T, Sakairi Y, Rahmutulla B, Ota S, Wada H, Suzuki H, Iwata T, Matsubara H, et al. Genetic alterations in squamous cell lung cancer associated with idiopathic pulmonary fibrosis. International Journal of Cancer. PMID 33533494 DOI: 10.1002/ijc.33499  0.123
2020 Seimiya T, Otsuka M, Iwata T, Shibata C, Tanaka E, Suzuki T, Koike K. Emerging Roles of Exosomal Circular RNAs in Cancer. Frontiers in Cell and Developmental Biology. 8: 568366. PMID 33117799 DOI: 10.3389/fcell.2020.568366  0.123
2020 Nishio H, Iwata T, Aoki D. Current status of cancer immunotherapy for gynecologic malignancies. Japanese Journal of Clinical Oncology. PMID 33244581 DOI: 10.1093/jjco/hyaa214  0.123
2009 Hossain MG, Iwata T, Mizusawa N, Qian ZR, Shima SW, Okutsu T, Yamada S, Sano T, Yoshimoto K. Expression of p18(INK4C) is down-regulated in human pituitary adenomas. Endocrine Pathology. 20: 114-21. PMID 19401813 DOI: 10.1007/s12022-009-9076-0  0.122
2017 Takeshita K, Motoike S, Kajiya M, Komatsu N, Takewaki M, Ouhara K, Iwata T, Takeda K, Mizuno N, Fujita T, Kurihara H. Xenotransplantation of interferon-gamma-pretreated clumps of a human mesenchymal stem cell/extracellular matrix complex induces mouse calvarial bone regeneration. Stem Cell Research & Therapy. 8: 101. PMID 28446226 DOI: 10.1186/s13287-017-0550-1  0.122
2017 Nakamura K, Yaguchi T, Ohmura G, Kobayashi A, Kawamura N, Iwata T, Kiniwa Y, Okuyama R, Kawakami Y. Involvement of local renin-angiotensin system in immunosuppression of tumor microenvironment. Cancer Science. PMID 29034589 DOI: 10.1111/cas.13423  0.122
2010 Nakao T, Kurita N, Komatsu M, Yoshikawa K, Iwata T, Utsunomiya T, Shimada M. Expression of thrombospondin-1 and Ski are prognostic factors in advanced gastric cancer. International Journal of Clinical Oncology. 16: 145-52. PMID 21107877 DOI: 10.1007/s10147-010-0147-5  0.122
2015 Nakao T, Iwata T, Hotchi M, Yoshikawa K, Higashijima J, Nishi M, Takasu C, Eto S, Teraoku H, Shimada M. Prediction of response to preoperative chemoradiotherapy and establishment of individualized therapy in advanced rectal cancer. Oncology Reports. 34: 1961-7. PMID 26260776 DOI: 10.3892/or.2015.4196  0.122
2022 Mizusawa N, Harada N, Iwata T, Ohigashi I, Itakura M, Yoshimoto K. Identification of protease serine S1 family member 53 as a mitochondrial protein in murine islet beta cells. Islets. 14: 1-13. PMID 34636707 DOI: 10.1080/19382014.2021.1982325  0.122
2021 Iwata T, Sedukhina AS, Kubota M, Oonuma S, Maeda I, Yoshiike M, Usuba W, Minagawa K, Hames E, Meguro R, Cho S, Chien SHH, Urabe S, Pae S, Palanisamy K, et al. A new bioinformatics approach identifies overexpression of GRB2 as a poor prognostic biomarker for prostate cancer. Scientific Reports. 11: 5696. PMID 33707553 DOI: 10.1038/s41598-021-85086-9  0.122
2018 Shiga Y, Akiyama M, Nishiguchi KM, Sato K, Shimozawa N, Takahashi A, Momozawa Y, Hirata M, Koichi M, Yamaji T, Iwasaki M, Tsugane S, Oze I, Mikami H, Naito M, ... ... Iwata T, et al. Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma. Human Molecular Genetics. PMID 29452408 DOI: 10.1093/Hmg/Ddy053  0.122
2010 Washio K, Iwata T, Mizutani M, Ando T, Yamato M, Okano T, Ishikawa I. Assessment of cell sheets derived from human periodontal ligament cells: a pre-clinical study. Cell and Tissue Research. 341: 397-404. PMID 20632035 DOI: 10.1007/s00441-010-1009-1  0.121
2020 Niimi H, Ohsugi Y, Katagiri S, Watanabe K, Hatasa M, Shimohira T, Tsuchiya Y, Maekawa S, Hirota T, Kadokura H, Yokose S, Iwata T, Aoki A. Effects of Low-Level Er:YAG Laser Irradiation on Proliferation and Calcification of Primary Osteoblast-Like Cells Isolated From Rat Calvaria. Frontiers in Cell and Developmental Biology. 8: 459. PMID 32656208 DOI: 10.3389/fcell.2020.00459  0.121
2017 Enoki Y, Sato T, Kokabu S, Hayashi N, Iwata T, Yamato M, Usui M, Matsumoto M, Tomoda T, Ariyoshi W, Nishihara T, Yoda T. Netrin-4 Promotes Differentiation and Migration of Osteoblasts. In Vivo (Athens, Greece). 31: 793-799. PMID 28882944  0.121
2023 Ikeo S, Yasuda N, Sakai Y, Hayashi Y, Sokai A, Iwata T, Nishimura T. Transient asymptomatic pulmonary opacities in a patient with MET exon 14 skipping non-small cell lung cancer: A case report. Thoracic Cancer. PMID 36810936 DOI: 10.1111/1759-7714.14831  0.121
2011 Kuwata T, Iwata T, Iwanami T. Napsin a and thyroid transcription factor-1-positive cerebellar tumor with epidermal growth factor receptor mutation. Case Reports in Oncology. 4: 564-8. PMID 22220151 DOI: 10.1159/000334925  0.121
1991 Mukaida H, Hirabayashi N, Hirai T, Iwata T, Saeki S, Toge T. Significance of freshly cultured fibroblasts from different tissues in promoting cancer cell growth. International Journal of Cancer. 48: 423-7. PMID 2040537 DOI: 10.1002/ijc.2910480320  0.121
2021 Shimohira T, Niimi H, Ohsugi Y, Tsuchiya Y, Morita K, Yoshida S, Hatasa M, Shiba T, Kadokura H, Yokose S, Katagiri S, Iwata T, Aoki A. Low-Level Erbium-Doped Yttrium Aluminum Garnet Laser Irradiation Induced Alteration of Gene Expression in Osteogenic Cells from Rat Calvariae. Photobiomodulation, Photomedicine, and Laser Surgery. PMID 34339325 DOI: 10.1089/photob.2020.4958  0.12
2020 Ishibashi F, Sakairi Y, Iwata T, Moriya Y, Mizobuchi T, Hoshino H, Yoshida S, Hanaoka H, Yoshino I, Motohashi S. A phase I study of loco-regional immunotherapy by transbronchial injection of α-galactosylceramide-pulsed antigen presenting cells in patients with lung cancer. Clinical Immunology (Orlando, Fla.). 215: 108457. PMID 32387537 DOI: 10.1016/j.clim.2020.108457  0.12
2002 Jishage K, Nezu J, Kawase Y, Iwata T, Watanabe M, Miyoshi A, Ose A, Habu K, Kake T, Kamada N, Ueda O, Kinoshita M, Jenne DE, Shimane M, Suzuki H. Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposis. Proceedings of the National Academy of Sciences of the United States of America. 99: 8903-8. PMID 12060709 DOI: 10.1073/pnas.122254599  0.12
2014 Kashihara H, Shimada M, Kurita N, Iwata T, Sato H, Kozo Yoshikawa, Higashijima J, Chikakiyo M, Nishi M, Matsumoto N. CD133 expression is correlated with poor prognosis in colorectal cancer. Hepato-Gastroenterology. 61: 1563-7. PMID 25436343 DOI: 10.5754/hge13657  0.12
2024 Uemura C, Nakahara A, Matsuo Y, Iwata T. Transition condition between memories of vibration and flow in the memory effect of paste. Physical Review. E. 109: 034604. PMID 38632748 DOI: 10.1103/PhysRevE.109.034604  0.12
2024 Aoyama T, Koide Y, Shimizu H, Kitagawa T, Iwata T, Hashimoto S, Tachibana H, Kodaira T. Trends and distribution of external radiation therapy facilities in Japan based on Survey of Medical Institutions from the Ministry of Health, Labour and Welfare. Journal of Radiation Research. PMID 38602048 DOI: 10.1093/jrr/rrae014  0.12
2024 Tsuboi I, Matsukawa A, Kardoust Parizi M, Klemm J, Mancon S, Chiujdea S, Fazekas T, Miszczyk M, Laukhtina E, Kawada T, Katayama S, Iwata T, Bekku K, Karakiewicz P, Wada K, et al. A Systematic Review and Meta-analysis of the Impact of Local Therapies on Local Event Suppression in Metastatic Hormone-sensitive Prostate Cancer. European Urology Oncology. PMID 38575408 DOI: 10.1016/j.euo.2024.03.007  0.12
2024 Tominaga Y, Kobayashi T, Matsumoto Y, Moriwake T, Oshima Y, Okumura M, Horii S, Sadahira T, Katayama S, Iwata T, Nishimura S, Bekku K, Edamura K, Sugimoto M, Kobayashi Y, et al. Trans men can achieve adequate muscular development through low-dose testosterone therapy: A long-term study on body composition changes. Andrology. PMID 38563871 DOI: 10.1111/andr.13640  0.12
2024 Liu A, Hayashi M, Ohsugi Y, Katagiri S, Akira S, Iwata T, Nakashima T. The IL-33/ST2 axis is protective against acute inflammation during the course of periodontitis. Nature Communications. 15: 2707. PMID 38548743 DOI: 10.1038/s41467-024-46746-2  0.12
2024 Taniguchi Y, Koyanagi T, Takagi T, Kitanaka Y, Aoki A, Iwata T. Ridge Preservation and Augmentation Using a Carbonated Apatite Bone Graft Substitute: A Case Series. Dentistry Journal. 12. PMID 38534279 DOI: 10.3390/dj12030055  0.12
2024 Matsuda S, Ueda T, Nakashima F, Ninomiya Y, Yasuda K, Sasaki S, Hamamoto Y, Iwata T, Ouhara K, Mihara N, Kakimoto N, Mizuno N. Predictive factors of periodontal regeneration outcomes using rhFGF-2: A case-control study. Journal of Periodontal Research. PMID 38527968 DOI: 10.1111/jre.13259  0.12
2024 Kiyota M, Iwata T, Hasegawa N, Sasaki S, Taniguchi Y, Hamamoto Y, Matsuda S, Ouhara K, Takeda K, Fujita T, Kurihara H, Kawaguchi H, Mizuno N. Periodontal tissue regeneration with cementogenesis after application of brain-derived neurotrophic factor in 3-wall inflamed intra-bony defect. Journal of Periodontal Research. PMID 38501357 DOI: 10.1111/jre.13244  0.12
2024 Nakagawa K, Watanabe K, Mizutani K, Takeda K, Takemura S, Sakaniwa E, Mikami R, Kido D, Saito N, Kominato H, Hattori A, Iwata T. Genetic analysis of impaired healing responses after periodontal therapy in type 2 diabetes: Clinical and in vivo studies. Journal of Periodontal Research. PMID 38501307 DOI: 10.1111/jre.13249  0.12
2024 Iwata T, Hirayama R, Yamada S, Kijima N, Okita Y, Kagawa N, Kishima H. Automated volumetry of meningiomas in contrast-enhanced T1-Weighted MRI using deep learning. World Neurosurgery: X. 22: 100353. PMID 38455247 DOI: 10.1016/j.wnsx.2024.100353  0.12
2024 Iwata T, Matsui T, Matsuda R, Katoh Y, Sugawara M, Nogami Y, Nishio H, Yamagami W. [Ⅰ. Immunotherapy in Cervical Cancer-Current Approaches and Future Horizons]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 51: 134-137. PMID 38449397  0.12
2024 Mizutani K, Minami I, Mikami R, Kido D, Takeda K, Nakagawa K, Takemura S, Saito N, Kominato H, Sakaniwa E, Konuma K, Izumi Y, Ogawa Y, Iwata T. Improvement of periodontal parameters following intensive diabetes care and supragingival dental prophylaxis in patients with type 2 diabetes: A prospective cohort study. Journal of Clinical Periodontology. PMID 38449337 DOI: 10.1111/jcpe.13958  0.12
2023 Mikami R, Komagamine Y, Aoyama N, Mizutani K, Sasaki Y, Iwata T, Minakuchi S, Kanazawa M. Association between occlusal supports and nutritional status in older adults: A systematic review. Journal of Dental Sciences. 19: 813-827. PMID 38618105 DOI: 10.1016/j.jds.2023.09.014  0.12
2022 Shimizu H, Sasaki K, Aoyama T, Iwata T, Kitagawa T, Kodaira T. Evaluation of a new acrylic-lead shielding device for peripheral dose reduction during cone-beam computed tomography. Bjr Open. 4: 20220043. PMID 38525166 DOI: 10.1259/bjro.20220043  0.12
2010 Sato T, Chida D, Iwata T, Usui M, Hatori K, Abe T, Takeda S, Yoda T. Non-neuronal regulation and repertoire of cholinergic receptors in organs. Biomolecular Concepts. 1: 357-66. PMID 25962009 DOI: 10.1515/bmc.2010.034  0.119
2010 Ayilavarapu S, Kantarci A, Fredman G, Turkoglu O, Omori K, Liu H, Iwata T, Yagi M, Hasturk H, Van Dyke TE. Diabetes-induced oxidative stress is mediated by Ca2+-independent phospholipase A2 in neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 184: 1507-15. PMID 20053941 DOI: 10.4049/jimmunol.0901219  0.119
2020 Hatasa M, Ohsugi Y, Katagiri S, Yoshida S, Niimi H, Morita K, Tsuchiya Y, Shimohira T, Sasaki N, Maekawa S, Shiba T, Hirota T, Tohara H, Takahashi H, Nitta H, ... Iwata T, et al. Endotoxemia by Alters Endocrine Functions in Brown Adipose Tissue. Frontiers in Cellular and Infection Microbiology. 10: 580577. PMID 33542905 DOI: 10.3389/fcimb.2020.580577  0.119
2014 Kobayashi H, Okamoto H, Murakami A, Iwata T. Plasma proteome analysis on cynomolgus monkey (Macaca fascicularis) pedigrees with early onset drusen formation. Experimental Animals / Japanese Association For Laboratory Animal Science. 63: 305-10. PMID 25077760 DOI: DN/JST.JSTAGE/expanim/13-0101  0.119
2022 Morita K, Nakamura A, Machida M, Kawasaki T, Nakanishi R, Ichida J, Iwata T, Umezawa A, Akutsu H. Efficient reprogramming of human fibroblasts using RNA reprogramming with DAPT and iDOT1L under normoxia conditions. Regenerative Therapy. 21: 389-397. PMID 36196449 DOI: 10.1016/j.reth.2022.09.002  0.119
2021 Iwata T, Mizuno N, Nagahara T, Kaneda-Ikeda E, Kajiya M, Sasaki S, Takeda K, Kiyota M, Yagi R, Fujita T, Kurihara H. Cytokines regulate stemness of mesenchymal stem cells via miR-628-5p during periodontal regeneration. Journal of Periodontology. PMID 34152611 DOI: 10.1002/JPER.21-0064  0.119
2021 Tanaka D, Ikeda Y, Ikeda E, Yokose M, Ganss B, Iwata T. Effect of Amelotin on Bone Growth in the Murine Calvarial Defect Model. Annals of Biomedical Engineering. 49: 3676-3684. PMID 34608582 DOI: 10.1007/s10439-021-02867-z  0.118
2011 Nishioka M, Shimada M, Kurita N, Iwata T, Morimoto S, Yoshikawa K, Higashijima J, Miyatani T, Kashihara H, Mikami C. A randomized phase II trial of chemoradiotherapy with oral fluoropyrimidine inhibitory for dihydropyrimidine dehydrogenase for low rectal cancer: An interim report. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 524. PMID 27985766 DOI: 10.1200/jco.2011.29.4_suppl.524  0.118
2011 Miyatani T, Kurita N, Mikami C, Kashihara H, Higashijima J, Yoshikawa K, Nishioka M, Sato H, Iwata T, Shimada M. Malignant potential of Barrett's esophagus: special reference to HDAC-1 and MTA-1 expression. Hepato-Gastroenterology. 58: 472-6. PMID 21661415  0.118
2022 Pan Y, Suga A, Kimura I, Kimura C, Minegishi Y, Nakayama M, Yoshitake K, Iejima D, Minematsu N, Yamamoto M, Mabuchi F, Takamoto M, Shiga Y, Araie M, Kashiwagi K, ... ... Iwata T, et al. METTL23 mutation alters histone H3R17 methylation in normal-tension glaucoma. The Journal of Clinical Investigation. PMID 36099048 DOI: 10.1172/JCI153589  0.118
2005 Iwata T, Uramoto H, Sugio K, Fujino Y, Oyama T, Nakata S, Ono K, Morita M, Yasumoto K. A lack of prognostic significance regarding DeltaNp63 immunoreactivity in lung cancer. Lung Cancer (Amsterdam, Netherlands). 50: 67-73. PMID 15950316 DOI: 10.1016/j.lungcan.2005.03.039  0.118
2018 Komatsu N, Kajiya M, Motoike S, Takewaki M, Horikoshi S, Iwata T, Ouhara K, Takeda K, Matsuda S, Fujita T, Kurihara H. Type I collagen deposition via osteoinduction ameliorates YAP/TAZ activity in 3D floating culture clumps of mesenchymal stem cell/extracellular matrix complexes. Stem Cell Research & Therapy. 9: 342. PMID 30526677 DOI: 10.1186/s13287-018-1085-9  0.118
2007 Banno K, Yanokura M, Kawaguchi M, Kuwabara Y, Akiyoshi J, Kobayashi Y, Iwata T, Hirasawa A, Fujii T, Susumu N, Tsukazaki K, Aoki D. Epigenetic inactivation of the CHFR gene in cervical cancer contributes to sensitivity to taxanes. International Journal of Oncology. 31: 713-20. PMID 17786301  0.118
2018 Motoike S, Kajiya M, Komatsu N, Takewaki M, Horikoshi S, Matsuda S, Ouhara K, Iwata T, Takeda K, Fujita T, Kurihara H. Cryopreserved clumps of mesenchymal stem cell/extracellular matrix complexes retain osteogenic capacity and induce bone regeneration. Stem Cell Research & Therapy. 9: 73. PMID 29562931 DOI: 10.1186/s13287-018-0826-0  0.118
2014 Izuhara Y, Matsumoto H, Kanemitsu Y, Izuhara K, Tohda Y, Horiguchi T, Kita H, Kuwabara K, Tomii K, Otsuka K, Fujimura M, Ohkura N, Tomita K, Yokoyama A, Ohnishi H, ... ... Iwata T, et al. GLCCI1 variant accelerates pulmonary function decline in patients with asthma receiving inhaled corticosteroids. Allergy. 69: 668-73. PMID 24673601 DOI: 10.1111/all.12400  0.117
2014 Gallenberger M, Kroeber M, März L, Koch M, Fuchshofer R, Braunger BM, Iwata T, Tamm ER. Heterozygote Wdr36-deficient mice do not develop glaucoma. Experimental Eye Research. 128: 83-91. PMID 25261604 DOI: 10.1016/j.exer.2014.09.008  0.117
2015 Yamada D, Iwata T, Yamamoto J, Hitomi K, Todo T, Iwai S, Getzoff ED, Kandori H. Structural role of two histidines in the (6-4) photolyase reaction. Biophysics and Physicobiology. 12: 139-44. PMID 27493863 DOI: 10.2142/Biophysico.12.0_139  0.117
2002 Futakuchi M, Cheng JL, Hirose M, Kimoto N, Cho YM, Iwata T, Kasai M, Tokudome S, Shirai T. Inhibition of conjugated fatty acids derived from safflower or perilla oil of induction and development of mammary tumors in rats induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Cancer Letters. 178: 131-9. PMID 11867197 DOI: 10.1016/s0304-3835(01)00860-6  0.117
2008 Gurel B, Iwata T, Koh CM, Jenkins RB, Lan F, Van Dang C, Hicks JL, Morgan J, Cornish TC, Sutcliffe S, Isaacs WB, Luo J, De Marzo AM. Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 21: 1156-67. PMID 18567993 DOI: 10.1038/Modpathol.2008.111  0.116
2021 Mikami R, Arisaka Y, Hakariya M, Iwata T, Yui N. Improved epithelial cell-cell adhesion using molecular mobility of supramolecular surfaces. Biomaterials Science. 9: 7151-7158. PMID 34605503 DOI: 10.1039/d1bm01356d  0.116
2019 Onizuka S, Iwata T. Application of Periodontal Ligament-Derived Multipotent Mesenchymal Stromal Cell Sheets for Periodontal Regeneration. International Journal of Molecular Sciences. 20. PMID 31181666 DOI: 10.3390/ijms20112796  0.116
1998 Futatani T, Miyawaki T, Tsukada S, Hashimoto S, Kunikata T, Arai S, Kurimoto M, Niida Y, Matsuoka H, Sakiyama Y, Iwata T, Tsuchiya S, Tatsuzawa O, Yoshizaki K, Kishimoto T. Deficient expression of Bruton's tyrosine kinase in monocytes from X-linked agammaglobulinemia as evaluated by a flow cytometric analysis and its clinical application to carrier detection. Blood. 91: 595-602. PMID 9427714  0.116
2006 Higashimoto Y, Yamagata Y, Iwata T, Ishiguchi T, Okada M, Masuda M, Satoh H, Itoh H. Adenoviral E1A suppresses secretory leukoprotease inhibitor and elafin secretion in human alveolar epithelial cells and bronchial epithelial cells. Respiration; International Review of Thoracic Diseases. 72: 629-35. PMID 16355004 DOI: 10.1159/000089579  0.116
2010 Maruta S, Miyata Y, Sagara Y, Kanda S, Iwata T, Watanabe SI, Sakai H, Hayashi T, Kanetake H. Expression of matrix metalloproteinase-10 in non-metastatic prostate cancer: Correlation with an imbalance in cell proliferation and apoptosis. Oncology Letters. 1: 417-421. PMID 22966318 DOI: 10.3892/ol_00000073  0.116
2020 Fukuhara N, Iwata T, Inoshita N, Yoshimoto K, Kitagawa M, Fukuhara H, Tatsushima K, Yamaguchi-Okada M, Takeshita A, Ito J, Takeuchi Y, Yamada S, Nishioka H. Immunohistochemistry or Molecular Analysis: Which Method Is Better for Subtyping Craniopharyngioma? Endocrine Pathology. PMID 32965631 DOI: 10.1007/s12022-020-09644-z  0.116
2017 Yaguchi T, Kobayashi A, Inozume T, Morii K, Nagumo H, Nishio H, Iwata T, Ka Y, Katano I, Ito R, Ito M, Kawakami Y. Human PBMC-transferred murine MHC class I/II-deficient NOG mice enable long-term evaluation of human immune responses. Cellular & Molecular Immunology. PMID 29151581 DOI: 10.1038/cmi.2017.106  0.115
2016 Iwata T, Watanabe A, Kusumoto M, Akiba M. Peptidoglycan acetylation of Campylobacter jejuni is essential for maintaining cell wall integrity and colonization in chicken intestine. Applied and Environmental Microbiology. PMID 27520822 DOI: 10.1128/AEM.02068-16  0.115
2021 Horikoshi S, Kajiya M, Motoike S, Yoshino M, Morimoto S, Yoshii H, Ogawa T, Sone H, Iwata T, Ouhara K, Matsuda S, Mizuno N, Kurihara H. Clumps of Mesenchymal Stem Cells/Extracellular Matrix Complexes Generated with Xeno-Free Chondro-Inductive Medium Induce Bone Regeneration via Endochondral Ossification. Biomedicines. 9. PMID 34680525 DOI: 10.3390/biomedicines9101408  0.115
1995 Iwata T, Galli C, Dainese P, Guerini D, Carafoli E. The 70 kD component of the heart sarcolemmal Na+/Ca(2+)-exchanger preparation is the C-terminal portion of the protein. Cell Calcium. 17: 263-9. PMID 7664313 DOI: 10.1016/0143-4160(95)90072-1  0.115
2015 Suemori T, Susumu N, Iwata T, Banno K, Yamagami W, Hirasawa A, Sugano K, Matsumoto E, Aoki D. Intratumoral CD8+ Lymphocyte Infiltration as a Prognostic Factor and Its Relationship With Cyclooxygenase 2 Expression and Microsatellite Instability in Endometrial Cancer. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. 25: 1165-72. PMID 26111272 DOI: 10.1097/IGC.0000000000000482  0.115
1979 Splitter GA, Incefy G, Iwata T, McGuire TC. Eveluation of functional thymic hormones in Arabian horses with severe combined immunodeficiency Clinical and Experimental Immunology. 38: 37-44. PMID 230925  0.114
2022 Hakariya M, Arisaka Y, Masuda H, Yoda T, Iwata T, Yui N. Suppressed Migration and Enhanced Cisplatin Chemosensitivity in Human Cancer Cell Lines by Tuning the Molecular Mobility of Supramolecular Biomaterials. Macromolecular Bioscience. e2200438. PMID 36461103 DOI: 10.1002/mabi.202200438  0.114
1992 Nara K, Aoyama Y, Iwata T, Hagiwara H, Hirose S. Cell cycle-dependent changes in tissue transglutaminase mRNA levels in bovine endothelial cells. Biochemical and Biophysical Research Communications. 187: 14-7. PMID 1355651 DOI: 10.1016/s0006-291x(05)81451-2  0.114
1973 Iwata T, Stowe BB. Probing a Membrane Matrix Regulating Hormone Action: II. The Kinetics of Lipid-Induced Growth and Ethylene Production. Plant Physiology. 51: 691-701. PMID 16658394 DOI: 10.1104/Pp.51.4.691  0.114
1999 Carper DA, Sun JK, Iwata T, Zigler JS, Ibaraki N, Lin LR, Reddy V. Oxidative stress induces differential gene expression in a human lens epithelial cell line. Investigative Ophthalmology & Visual Science. 40: 400-6. PMID 9950599  0.114
1984 Higashida H, Miki N, Ito M, Iwata T, Tsukida K. Cytotoxic action of retinoidal butenolides on mouse neuroblastoma and rat glioma cells. International Journal of Cancer. 33: 677-81. PMID 6724742 DOI: 10.1002/ijc.2910330519  0.113
1996 Gabellini N, Iwata T, Carafoli E. Expression of Na(+)-Ca2+ exchanger with modified C-terminal hydrophobic domains and enhanced activity. Annals of the New York Academy of Sciences. 779: 110-4. PMID 8659816 DOI: 10.1111/j.1749-6632.1996.tb44775.x  0.113
2005 Kikuyama S, Nakada T, Toyoda F, Iwata T, Yamamoto K, Conlon JM. Amphibian pheromones and endocrine control of their secretion. Annals of the New York Academy of Sciences. 1040: 123-30. PMID 15891015 DOI: 10.1196/annals.1327.015  0.113
2015 Iwata T, Washio K, Yoshida T, Ishikawa I, Ando T, Yamato M, Okano T. Cell sheet engineering and its application for periodontal regeneration. Journal of Tissue Engineering and Regenerative Medicine. 9: 343-56. PMID 23881816 DOI: 10.1002/term.1785  0.113
2019 Inoue J, Ninomiya M, Umetsu T, Nakamura T, Kogure T, Kakazu E, Iwata T, Takai S, Sano A, Fukuda M, Watashi K, Isogawa M, Tanaka Y, Shimosegawa T, McNiven MA, et al. siRNA Screening for the Small GTPase Rab Proteins Identifies that Rab5B is a Major Regulator of Hepatitis B Virus Production. Journal of Virology. PMID 31118260 DOI: 10.1128/JVI.00621-19  0.113
2019 Kato Y, Arakawa S, Terasawa K, Inokuchi JI, Iwata T, Shimizu S, Watabe T, Hara-Yokoyama M. The ceramide analogue N-(1-hydroxy-3-morpholino-1-phenylpropan-2-yl)decanamide induces large lipid droplet accumulation and highlights the effect of LAMP-2 deficiency on lipid droplet degradation. Bioorganic & Medicinal Chemistry Letters. 126891. PMID 31874824 DOI: 10.1016/J.Bmcl.2019.126891  0.113
2005 Higashimoto Y, Ohata M, Yamagata Y, Iwata T, Masuda M, Ishiguchi T, Okada M, Satoh H, Itoh H. Effect of the adenovirus E1A gene on nitric oxide production in alveolar epithelial cells. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. 11: 644-50. PMID 16008617 DOI: 10.1111/j.1469-0691.2005.01188.x  0.113
2021 Hayashi S, Iwata T, Imagawa R, Sugawara M, Chen G, Tanimoto S, Sugawara Y, Tanaka I, Matsui T, Nishio H, Nakamura M, Katoh Y, Mori S, Kukimoto I, Aoki D. Transcription Factor Homeobox D9 Drives the Malignant Phenotype of HPV18-Positive Cervical Cancer Cells via Binding to the Viral Early Promoter. Cancers. 13. PMID 34572841 DOI: 10.3390/cancers13184613  0.113
2012 Tanaka K, Shirotsuki S, Iwata T, Kageyama C, Tahara T, Nozaki S, Siwu ER, Tamura S, Douke S, Murakami N, Onoe H, Watanabe Y, Fukase K. Template-assisted and self-activating clicked peptide as a synthetic mimic of the SH2 domain. Acs Chemical Biology. 7: 637-45. PMID 22239652 DOI: 10.1021/cb2003175  0.113
2009 Iwata T, Yamato M, Tsuchioka H, Takagi R, Mukobata S, Washio K, Okano T, Ishikawa I. Periodontal regeneration with multi-layered periodontal ligament-derived cell sheets in a canine model. Biomaterials. 30: 2716-23. PMID 19201461 DOI: 10.1016/j.biomaterials.2009.01.032  0.113
2007 Miyata Y, Iwata T, Ohba K, Kanda S, Nishikido M, Kanetake H. Expression of matrix metalloproteinase-7 on cancer cells and tissue endothelial cells in renal cell carcinoma: prognostic implications and clinical significance for invasion and metastasis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 6998-7003. PMID 17145820 DOI: 10.1158/1078-0432.CCR-06-1626  0.113
2017 Shinozaki Y, Kashiwagi K, Namekata K, Takeda A, Ohno N, Robaye B, Harada T, Iwata T, Koizumi S. Purinergic dysregulation causes hypertensive glaucoma-like optic neuropathy. Jci Insight. 2. PMID 28978804 DOI: 10.1172/jci.insight.93456  0.113
2011 Higashijima J, Kurita N, Miyatani T, Yoshikawa K, Morimoto S, Nishioka M, Iwata T, Shimada M. Expression of histone deacetylase 1 and metastasis-associated protein 1 as prognostic factors in colon cancer. Oncology Reports. 26: 343-8. PMID 21617866 DOI: 10.3892/or.2011.1312  0.112
2010 Sagara Y, Miyata Y, Iwata T, Kanda S, Hayashi T, Sakai H, Kanetake H. Clinical significance and prognostic value of S100A4 and matrix metalloproteinase-14 in patients with organ-confined bladder cancer. Experimental and Therapeutic Medicine. 1: 27-31. PMID 23136588 DOI: 10.3892/etm_00000005  0.112
2020 Janisch F, D'Andrea D, Iwata T, Kimura S, Abufaraj M, Enikeev D, Glybochko PV, Karakiewicz PI, Nyirady P, Fajkovic H, Haitel A, Seebacher V, Rink M, Shariat SF. The prognostic value of the urokinase-plasminogen activator system (uPA) in bladder cancer patients treated with radical cystectomy (RC). Urologic Oncology. PMID 32209281 DOI: 10.1016/j.urolonc.2020.02.002  0.112
2010 Watanabe SI, Miyata Y, Kanda S, Iwata T, Hayashi T, Kanetake H, Sakai H. Expression of X-linked inhibitor of apoptosis protein in human prostate cancer specimens with and without neo-adjuvant hormonal therapy Journal of Cancer Research and Clinical Oncology. 136: 787-793. PMID 19946707 DOI: 10.1007/s00432-009-0718-x  0.112
2001 Kikuyama S, Yazawa T, Abe S, Yamamoto K, Iwata T, Hoshi K, Hasunuma I, Mosconi G, Polzonetti-Magni AM. Newt prolactin and its involvement in reproduction. Canadian Journal of Physiology and Pharmacology. 78: 984-93. PMID 11149387  0.112
2021 Lin P, Niimi H, Ohsugi Y, Tsuchiya Y, Shimohira T, Komatsu K, Liu A, Shiba T, Aoki A, Iwata T, Katagiri S. Application of Ligature-Induced Periodontitis in Mice to Explore the Molecular Mechanism of Periodontal Disease. International Journal of Molecular Sciences. 22. PMID 34445604 DOI: 10.3390/ijms22168900  0.112
2018 Suzuki H, Nishida H, Kondo H, Yoda R, Iwata T, Nakayama K, Enomoto T, Wu J, Moriya-Ito K, Miyazaki M, Wakabayashi Y, Kishida T, Okabe M, Suzuki Y, Ito T, et al. A single pheromone receptor gene conserved across 400 million years of vertebrate evolution. Molecular Biology and Evolution. PMID 30252081 DOI: 10.1093/Molbev/Msy186  0.111
2022 Ogawa T, Kajiya M, Horikoshi S, Yoshii H, Yoshino M, Motoike S, Morimoto S, Sone H, Iwata T, Ouhara K, Matsuda S, Mizuno N. Xenotransplantation of cryopreserved human clumps of mesenchymal stem cells/extracellular matrix complexes pretreated with IFN-γ induces rat calvarial bone regeneration. Regenerative Therapy. 20: 117-125. PMID 35582709 DOI: 10.1016/j.reth.2022.04.003  0.111
2019 Yamamoto A, Iwata T. [Efforts to Reduce the Risk of Febrile Neutropenia and to Increase the Response Rate to Docetaxel and Ramucirumab Therapy in Patients with Non-Small Cell Lung Cancer]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 46: 1421-1425. PMID 31530782  0.111
2020 Fujinami K, Oishi A, Yang L, Arno G, Pontikos N, Yoshitake K, Fujinami-Yokokawa Y, Liu X, Hayashi T, Katagiri S, Mizobuchi K, Mizota A, Shinoda K, Nakamura N, Kurihara T, ... ... Iwata T, et al. Clinical and genetic characteristics of 10 Japanese patients with PROM1-associated retinal disorder: A report of the phenotype spectrum and a literature review in the Japanese population. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. e31826. PMID 32820593 DOI: 10.1002/ajmg.c.31826  0.111
2010 Chi ZL, Yasumoto F, Sergeev Y, Minami M, Obazawa M, Kimura I, Takada Y, Iwata T. Mutant WDR36 directly affects axon growth of retinal ganglion cells leading to progressive retinal degeneration in mice. Human Molecular Genetics. 19: 3806-15. PMID 20631153 DOI: 10.1093/hmg/ddq299  0.111
1976 Iwata T. Cytochemical studies on endogenous peroxidase in conjunctival and corneal epithelial cells. Investigative Ophthalmology. 15: 297-301. PMID 1262160  0.111
2007 Iwata T, Inoue K, Nishiyama N, Izumi N, Mizuguchi S, Morita R, Tsukioka T, Suehiro S, Obatake N, Wakasa K. Pulmonary inverted Schneiderian papilloma causing high serum levels of carcinoembryonic antigen and squamous cell carcinoma-associated antigen: report of a case. Surgery Today. 37: 790-3. PMID 17713735 DOI: 10.1007/s00595-007-3489-5  0.111
2022 Iwata T, Kaneda-Ikeda E, Takahashi K, Takeda K, Nagahara T, Kajiya M, Sasaki S, Ishida S, Yoshioka M, Matsuda S, Ouhara K, Fujita T, Kurihara H, Mizuno N. Regulation of osteogenesis in bone marrow-derived mesenchymal stem cells via histone deacetylase 1 and 2 co-cultured with human gingival fibroblasts and periodontal ligament cells. Journal of Periodontal Research. PMID 36346011 DOI: 10.1111/jre.13070  0.111
2011 Morimoto S, Shimada M, Kurita N, Iwata T, Nishioka M, Yoshikawa K, Miyatani T, Mikami C, Kashihara H. The role of UGT1A1 polymorphisms (*28 and *6) in Japanese cancer patients. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 570. PMID 27985925 DOI: 10.1200/jco.2011.29.4_suppl.570  0.11
2019 Kubota D, Oishi N, Gocho K, Kikuchi S, Yamaki K, Igarashi T, Takahashi H, Ishida N, Iwata T, Mizota A, Kameya S. Novel homozygous in-frame deletion of gene causes golden appearance of fundus and reduced scotopic ERGs similar to that in Oguchi disease in Japanese family. Ophthalmic Genetics. 40: 480-487. PMID 31696758 DOI: 10.1080/13816810.2019.1686159  0.11
2023 Yagasaki L, Chiba T, Kurimoto R, Nakajima M, Iwata T, Asahara H. The essential role of in periodontal ligament on the metabolism of alveolar bone and cementum. Regenerative Therapy. 25: 186-193. PMID 38230307 DOI: 10.1016/j.reth.2023.12.007  0.11
2024 Omura T, Isobe N, Miura T, Ishii S, Mori M, Ishitani Y, Kimura S, Hidaka K, Komiyama K, Suzuki M, Kasuya KI, Nomaki H, Nakajima R, Tsuchiya M, Kawagucci S, ... ... Iwata T, et al. Microbial decomposition of biodegradable plastics on the deep-sea floor. Nature Communications. 15: 568. PMID 38278791 DOI: 10.1038/s41467-023-44368-8  0.11
2015 Tanito M, Hara K, Akahori M, Harata A, Itabashi T, Takai Y, Kaidzu S, Ohira A, Iwata T. Lack of association of LOXL1 gene variants in Japanese patients with central retinal vein occlusion without clinically detectable pseudoexfoliation material deposits. Acta Ophthalmologica. 93: e214-7. PMID 25130441 DOI: 10.1111/aos.12534  0.11
2004 Kano H, Ito Y, Matsuoka K, Nakajima T, Iwata T, Kohsaka T, Saito H, Abe J. Critical role of T cell migration in bacterial superantigen-mediated shock in mice. Clinical Immunology (Orlando, Fla.). 110: 159-71. PMID 15003813 DOI: 10.1016/j.clim.2003.10.009  0.11
2011 Nishioka M, Shimada M, Kurita N, Iwata T, Morimoto S, Yoshikawa K, Higashijima J, Miyatani T. Gene expression profile can predict pathological response to preoperative chemoradiotherapy in rectal cancer. Cancer Genomics & Proteomics. 8: 87-92. PMID 21471518  0.11
2011 Chi ZL, Yoshida T, Lambris JD, Iwata T. Suppression of drusen formation by compstatin, a peptide inhibitor of complement C3 activation, on cynomolgus monkey with early-onset macular degeneration. Advances in Experimental Medicine and Biology. 703: 127-35. PMID 20711711 DOI: 10.1007/978-1-4419-5635-4_9  0.11
2001 Cui SH, Tanabe F, Terunuma H, Iwatani Y, Nunoi H, Agematsu K, Komiyama A, Nomura A, Hara T, Onodera T, Iwata T, Ito M. A thiol proteinase inhibitor, E-64-d, corrects the abnormalities in concanavalin A cap formation and the lysosomal enzyme activity in leucocytes from patients with Chediak-Higashi syndrome by reversing the down-regulated protein kinase C activity. Clinical and Experimental Immunology. 125: 283-90. PMID 11529921 DOI: 10.1046/j.1365-2249.2001.01598.x  0.11
2023 Tsukiyama I, Iwata T, Takeuchi T, Kato RI, Sakuma M, Tsukiyama S, Kato M, Ikeda Y, Ohashi W, Kubo A, Mori N. Factors associated with early discontinuation of anamorelin in patients with cancer-associated cachexia. Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer. 31: 621. PMID 37815652 DOI: 10.1007/s00520-023-08097-4  0.11
2001 Ueda J, Iwata T, Takahashi M, Hoshii Y, Ishihara T. Comparative immunochemical study of lectin-binding sites and cytoskeletal filaments in static and reactive mesothelium and adenocarcinoma. Pathology International. 51: 431-9. PMID 11422804 DOI: 10.1046/j.1440-1827.2001.01217.x  0.11
2014 Wijaya IM, Iwata T, Yamamoto J, Hitomi K, Iwai S, Getzoff ED, Kennis JT, Mathes T, Kandori H. Flavin adenine dinucleotide chromophore charge controls the conformation of cyclobutane pyrimidine dimer photolyase α-helices. Biochemistry. 53: 5864-75. PMID 25152314 DOI: 10.1021/Bi500638B  0.109
2019 Kimura S, D'Andrea D, Iwata T, Foerster B, Janisch F, Parizi MK, Moschini M, Briganti A, Babjuk M, Chlosta P, Karakiewicz PI, Enikeev D, Rapoport LM, Seebacher V, Egawa S, et al. Expression of urokinase-type plasminogen activator system in non-metastatic prostate cancer. World Journal of Urology. PMID 31797075 DOI: 10.1007/s00345-019-03038-5  0.109
1995 Iwata T, Popescu NC, Zimonjic DB, Karlsson C, Höög JO, Vaca G, Rodriguez IR, Carper D. Structural organization of the human sorbitol dehydrogenase gene (SORD). Genomics. 26: 55-62. PMID 7782086  0.109
2011 Iwanami T, Uramoto H, Baba T, Takenaka M, Yokoyama E, Oka S, So T, Ono K, So T, Takenoyama M, Hanagiri T, Iwata T, Inoue M, Yasumoto K. [Treatment recommendations for adrenal metastasis of non-small cell lung cancer]. Kyobu Geka. the Japanese Journal of Thoracic Surgery. 63: 1101-6; discussion 1. PMID 21174656  0.109
2002 Iwata T, Kohyama N, Yano E. Chemiluminescent detection of induced reactive oxygen metabolite production of human polymorphonuclear leucocytes by anthophyllite asbestos. Environmental Research. 88: 36-40. PMID 11896666 DOI: 10.1006/enrs.2001.4314  0.109
1995 Gabellini N, Iwata T, Carafoli E. An alternative splicing site modifies the carboxyl-terminal trans-membrane domains of the Na+/Ca2+ exchanger. The Journal of Biological Chemistry. 270: 6917-24. PMID 7896841 DOI: 10.1074/jbc.270.12.6917  0.109
2016 Kaibuchi N, Iwata T, Yamato M, Okano T, Ando T. Multipotent mesenchymal stromal cell sheet therapy for bisphosphonate-related osteonecrosis of the jaw in a rat model. Acta Biomaterialia. PMID 27326918 DOI: 10.1016/j.actbio.2016.06.022  0.109
2005 Yamakoshi Y, Hu JC, Fukae M, Iwata T, Kim JW, Zhang H, Simmer JP. Porcine dentin sialoprotein is a proteoglycan with glycosaminoglycan chains containing chondroitin 6-sulfate. The Journal of Biological Chemistry. 280: 1552-60. PMID 15537641 DOI: 10.1074/jbc.M409606200  0.108
2018 Shim MS, Kim KY, Noh M, Ko JY, Ahn S, An MA, Iwata T, Perkins GA, Weinreb RN, Ju WK. Optineurin E50K triggers BDNF deficiency-mediated mitochondrial dysfunction in retinal photoreceptor cell line. Biochemical and Biophysical Research Communications. PMID 30100066 DOI: 10.1016/j.bbrc.2018.08.025  0.108
2012 Kashihara H, Shimada M, Kurita N, Nishioka M, Iwata T, Sato H, Morimoto S, Yoshikawa K, Miyatani T, Mikami C. Feasibility study of irinotecan based on UGT1A1 polymorphisms for metastatic colorectal cancer: Interim report. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 505. PMID 27983370 DOI: 10.1200/jco.2012.30.4_suppl.505  0.108
2014 Enoki Y, Sato T, Tanaka S, Iwata T, Usui M, Takeda S, Kokabu S, Matsumoto M, Okubo M, Nakashima K, Yamato M, Okano T, Fukuda T, Chida D, Imai Y, et al. Netrin-4 derived from murine vascular endothelial cells inhibits osteoclast differentiation in vitro and prevents bone loss in vivo. Febs Letters. 588: 2262-9. PMID 24846137 DOI: 10.1016/j.febslet.2014.05.009  0.108
2004 Izumi K, Mashima Y, Obazawa M, Ohtake Y, Tanino T, Miyata H, Zhang Q, Oguchi Y, Tanaka Y, Iwata T. Variants of the myocilin gene in Japanese patients with normal-tension glaucoma. Ophthalmic Research. 35: 345-50. PMID 14688426 DOI: 10.1159/000074075  0.108
2016 Shim MS, Takihara Y, Kim KY, Iwata T, Yue BY, Inatani M, Weinreb RN, Perkins GA, Ju WK. Mitochondrial pathogenic mechanism and degradation in optineurin E50K mutation-mediated retinal ganglion cell degeneration. Scientific Reports. 6: 33830. PMID 27654856 DOI: 10.1038/Srep33830  0.108
1991 Saheki T, Mizuno T, Iwata T, Saito Y, Nagasawa T, Mizuno KU, Ito F, Ito T, Hagiwara H, Hirose S. Structure of the bovine atrial natriuretic peptide receptor (type C) gene. The Journal of Biological Chemistry. 266: 11122-5. PMID 1645726  0.108
2011 Koh CM, Gurel B, Sutcliffe S, Aryee MJ, Schultz D, Iwata T, Uemura M, Zeller KI, Anele U, Zheng Q, Hicks JL, Nelson WG, Dang CV, Yegnasubramanian S, De Marzo AM. Alterations in nucleolar structure and gene expression programs in prostatic neoplasia are driven by the MYC oncogene. The American Journal of Pathology. 178: 1824-34. PMID 21435462 DOI: 10.1016/J.Ajpath.2010.12.040  0.108
1994 Kitami Y, Okura T, Wakamiya R, Marumoto K, Iwata T, Hiwada K. Regulation of the gene expression of type-1 angiotensin II receptor in spontaneously hypertensive rats. Blood Pressure. Supplement. 3: 12-6. PMID 1343280  0.108
1990 Iwata T, Kojima R, Nagamatsu T, Ito M, Suzuki Y. [Studies on initiation and progression of focal glomerular sclerosis in rats]. Nihon Jinzo Gakkai Shi. 31: 1105-15. PMID 2625736  0.108
2021 Janisch F, Kienapfel C, Fühner C, Klotzbücher T, Marks P, Hillemacher T, Meyer CP, Iwata T, Parizi MK, Sauter G, Fisch M, Shariat SF, Dahlem R, Rink M. Treatment and Outcome of Metastatic Renal Cell Carcinoma With Sarcomatoid Differentiation: A Single-Center, Real-World Analysis of Retrospective Data. Frontiers in Surgery. 8: 763271. PMID 34869564 DOI: 10.3389/fsurg.2021.763271  0.108
2012 Sato H, Shimada M, Kurita N, Iwata T, Nishioka M, Morimoto S, Yoshikawa K, Miyatani T, Goto M, Kashihara H, Mikami C. Assessment of gastric cancer malignancy based on CD133 and thrombospondin1 (THBS1) expression and the role of histone acetylation. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 31. PMID 27982971 DOI: 10.1200/jco.2012.30.4_suppl.31  0.107
2000 Iwata T, Kawahara G, Yamamoto K, Zhou CJ, Nakajo S, Shioda S, Kikuyama S. Effect of prolactin and androgen on the expression of the female-attracting pheromone silefrin in the abdominal gland of the newt, Cynops ensicauda Biology of Reproduction. 63: 1867-1872. PMID 11090459  0.107
2020 Li H, Yuan S, Minegishi Y, Suga A, Yoshitake K, Sheng X, Ye J, Smith S, Bunkoczi G, Yamamoto M, Iwata T. Novel mutations in malonyl-CoA-acyl carrier protein transacylase provoke autosomal recessive optic neuropathy. Human Molecular Genetics. PMID 31915829 DOI: 10.1093/hmg/ddz311  0.107
2016 Yamazaki S, Ohtsuka Y, Yokokura T, Yokota R, Honjo A, Inage E, Baba Y, Mori M, Suzuki R, Iwata T, Shimizu T. Eosinophilic gastroenteritis in a patient with Bruton's tyrosine kinase deficiency. Pediatrics International : Official Journal of the Japan Pediatric Society. PMID 26840762 DOI: 10.1111/ped.12823  0.107
2003 Umeda S, Ayyagari R, Suzuki MT, Ono F, Iwata F, Fujiki K, Kanai A, Takada Y, Yoshikawa Y, Tanaka Y, Iwata T. Molecular cloning of ELOVL4 gene from cynomolgus monkey (Macaca fascicularis). Experimental Animals / Japanese Association For Laboratory Animal Science. 52: 129-35. PMID 12806887  0.107
2017 Kato Y, Hanazono G, Fujinami K, Hatase T, Kawamura Y, Iwata T, Miyake Y, Tsunoda K. Parafoveal Photoreceptor Abnormalities in Asymptomatic Patients With RP1L1 Mutations in Families With Occult Macular Dystrophy. Investigative Ophthalmology & Visual Science. 58: 6020-6029. PMID 29196766 DOI: 10.1167/iovs.17-21969  0.107
1999 Nishida T, Inoue K, Kato T, Iwata T, Kinoshita H, Kaneda K. Localization and ultrastructure of pulmonary dendritic cells during delayed-type hypersensitivity reactions in mice. Cell and Tissue Research. 297: 485-92. PMID 10460495 DOI: 10.1007/s004410051375  0.106
1989 Cole FE, Rovigatti U, Iwata T, Vaughn J, Frohlich ED. Atrial natriuretic factor effects on cyclic nucleotides in a human renal cell line. Hypertension (Dallas, Tex. : 1979). 13: 799-803. PMID 2567705 DOI: 10.1161/01.hyp.13.6.799  0.106
1998 Kasuya K, Inoue Y, Tanaka T, Akehata T, Iwata T, Fukui T, Doi Y. Biochemical and molecular characterization of the polyhydroxybutyrate depolymerase of Comamonas acidovorans YM1609, isolated from freshwater. Applied and Environmental Microbiology. 63: 4844-52. PMID 9406404 DOI: 10.1128/aem.63.12.4844-4852.1997  0.106
2020 Fujinami K, Liu X, Ueno S, Mizota A, Shinoda K, Kuniyoshi K, Fujinami-Yokokawa Y, Yang L, Arno G, Pontikos N, Kameya S, Kominami T, Terasaki H, Sakuramoto H, Nakamura N, ... ... Iwata T, et al. RP2-associated retinal disorder in a Japanese cohort: Report of novel variants and a literature review, identifying a genotype-phenotype association. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. PMID 32875684 DOI: 10.1002/ajmg.c.31830  0.106
2010 Iwata T, Zhang Y, Hitomi K, Getzoff ED, Kandori H. Key dynamics of conserved asparagine in a cryptochrome/photolyase family protein by fourier transform infrared spectroscopy. Biochemistry. 49: 8882-91. PMID 20828134 DOI: 10.1021/Bi1009979  0.106
2023 Toyoshima K, Ohsugi Y, Lin P, Komatsu K, Shiba T, Takeuchi Y, Hirota T, Shimohira T, Tsuchiya Y, Katagiri S, Iwata T, Aoki A. Blue Light-Emitting Diode Irradiation Without a Photosensitizer Alters Oral Microbiome Composition of Ligature-Induced Periodontitis in Mice. Photobiomodulation, Photomedicine, and Laser Surgery. 41: 549-559. PMID 37788456 DOI: 10.1089/photob.2023.0061  0.106
2022 Kayazawa T, Kuniyoshi K, Hatsukawa Y, Fujinami K, Yoshitake K, Tsunoda K, Shimojo H, Iwata T, Kusaka S. Clinical course of a Japanese girl with Leber congenital amaurosis associated with a novel nonsense pathogenic variant in : a case report and mini review. Ophthalmic Genetics. 1-9. PMID 35026968 DOI: 10.1080/13816810.2021.2023195  0.106
2007 Iwata T, Kurita N, Nishioka M, Miyamoto H, Wakatsuki S, Sano T, Tashiro S, Shimada M. p53 and MIB-1 expression of esophageal carcinoma concominant with achalasia. Hepato-Gastroenterology. 54: 1430-2. PMID 17708270  0.106
1994 Okura T, Kitami Y, Wakamiya R, Marumoto K, Iwata T, Hiwada K. Renal and extra-renal renin gene expression in spontaneously hypertensive rats. Blood Pressure. Supplement. 3: 6-11. PMID 1343292  0.106
2022 Ahamed W, Yu RMC, Pan Y, Iwata T, Barathi VA, Wey YS, Tun SBB, Qiu B, Tan A, Wang X, Cheung CMG, Wong TY, Yanagi Y. Regulates Subclinical Inflammation and Activates Proangiogenic Response in the Retina and Choroid. International Journal of Molecular Sciences. 23. PMID 36142120 DOI: 10.3390/ijms231810206  0.105
2023 Masuda H, Arisaka Y, Hakariya M, Iwata T, Yoda T, Yui N. Molecular Mobility of Polyrotaxane Surfaces Alleviates Oxidative Stress-Induced Senescence in Mesenchymal Stem Cells. Macromolecular Bioscience. e2300053. PMID 36942889 DOI: 10.1002/mabi.202300053  0.105
2017 Nagase K, Sakurada Y, Onizuka S, Iwata T, Yamato M, Takeda N, Okano T. Thermoresponsive Polymer-Modified Microfibers for Cell Separations. Acta Biomaterialia. PMID 28219809 DOI: 10.1016/j.actbio.2017.02.033  0.105
2019 Iwata T, Kimura S, Abufaraj M, Janisch F, Parizi MK, Haitel A, Rink M, Rouprêt M, Fajkovic H, Seebacher V, Nyirady P, Karakiewicz PI, Enikeev D, Rapoport LM, Nasu Y, et al. Prognostic role of the urokinase plasminogen activator (uPA) system in patients with nonmuscle invasive bladder cancer. Urologic Oncology. PMID 31255543 DOI: 10.1016/j.urolonc.2019.05.019  0.105
2010 Akahori M, Tsunoda K, Miyake Y, Fukuda Y, Ishiura H, Tsuji S, Usui T, Hatase T, Nakamura M, Ohde H, Itabashi T, Okamoto H, Takada Y, Iwata T. Dominant mutations in RP1L1 are responsible for occult macular dystrophy. American Journal of Human Genetics. 87: 424-9. PMID 20826268 DOI: 10.1016/j.ajhg.2010.08.009  0.105
2000 Sun JK, Iwata T, Zigler JS, Carper DA. Differential gene expression in male and female rat lenses undergoing cataract induction by transforming growth factor-beta (TGF-beta). Experimental Eye Research. 70: 169-81. PMID 10655142 DOI: 10.1006/exer.1999.0771  0.105
2011 Iwata T, Nozu F, Imawari M. Ethanol impairs the assembly and disassembly of actin cytoskeleton and cell adhesion via the RhoA signaling pathway, catenin p120 and E-cadherin in CCK-stimulated pancreatic acini. Biochemical and Biophysical Research Communications. 405: 558-63. PMID 21262198 DOI: 10.1016/j.bbrc.2011.01.067  0.105
2008 Iwata T, Inoue K, Kiriike S, Izumi N, Mizuguchi S, Tsukioka T, Morita R, Nishiyama N, Takemura M, Osugi H, Wakasa K, Suehiro S. Hemorrhagic small intestine cancer with solitary pulmonary metastasis initially presented as suspected primary lung cancer: an autopsy report. Osaka City Medical Journal. 53: 109-16. PMID 18432067  0.105
2008 Omori K, Ohira T, Uchida Y, Ayilavarapu S, Batista EL, Yagi M, Iwata T, Liu H, Hasturk H, Kantarci A, Van Dyke TE. Priming of neutrophil oxidative burst in diabetes requires preassembly of the NADPH oxidase. Journal of Leukocyte Biology. 84: 292-301. PMID 18390927 DOI: 10.1189/jlb.1207832  0.104
2017 Shim MS, Takihara Y, Kim KY, Iwata T, Yue BY, Inatani M, Weinreb RN, Perkins GA, Ju WK. Corrigendum: Mitochondrial pathogenic mechanism and degradation in optineurin E50K mutation-mediated retinal ganglion cell degeneration. Scientific Reports. 7: 40460. PMID 28102236 DOI: 10.1038/srep40460  0.104
2016 Yamada D, Dokainish HM, Iwata T, Yamamoto J, Ishikawa T, Todo T, Iwai S, Getzoff ED, Kitao A, Kandori H. Functional Conversion of CPD and (6-4) Photolyases by Mutation. Biochemistry. PMID 27431478 DOI: 10.1021/Acs.Biochem.6B00361  0.104
2020 Kuniyoshi K, Hayashi T, Kameya S, Katagiri S, Mizobuchi K, Tachibana T, Kubota D, Sakuramoto H, Tsunoda K, Fujinami K, Yoshitake K, Iwata T, Nakano T, Kusaka S. Clinical Course and Electron Microscopic Findings in Lymphocytes of Patients with -Associated Retinopathy. International Journal of Molecular Sciences. 21. PMID 32079136 DOI: 10.3390/ijms21041331  0.104
2013 Kittaka M, Shiba H, Kajiya M, Fujita T, Iwata T, Rathvisal K, Ouhara K, Takeda K, Fujita T, Komatsuzawa H, Kurihara H. The antimicrobial peptide LL37 promotes bone regeneration in a rat calvarial bone defect. Peptides. 46: 136-42. PMID 23770151 DOI: 10.1016/j.peptides.2013.06.001  0.104
2007 Iwata T, Kurita N, Nishioka M, Hidenori M, Wakatsuki S, Sano T, Shimada M. Usefulness of cytokeratin immunoreactivity pattern for distinction of Barrett's esophagus from intestinal metaplasia of the stomach. Hepato-Gastroenterology. 54: 1710-2. PMID 18019700  0.104
1998 Chikama T, Yoshino H, Nishida T, Nagasawa T, Takahashi M, Iwata T. Langerhans cell histiocytosis localized to the eyelid. Archives of Ophthalmology (Chicago, Ill. : 1960). 116: 1375-7. PMID 9790643 DOI: 10.1001/archopht.116.10.1375  0.104
2000 Kanegane H, Tsukada S, Iwata T, Futatani T, Nomura K, Yamamoto J, Yoshida T, Agematsu K, Komiyama A, Miyawaki T. Detection of Bruton's tyrosine kinase mutations in hypogammaglobulinaemic males registered as common variable immunodeficiency (CVID) in the Japanese Immunodeficiency Registry. Clinical and Experimental Immunology. 120: 512-7. PMID 10844531 DOI: 10.1046/j.1365-2249.2000.01244.x  0.104
2016 Kuniyoshi K, Hayashi T, Sakuramoto H, Mishima H, Tsuneoka H, Tsunoda K, Iwata T, Shimomura Y. New truncation mutation of the NR2E3 gene in a Japanese patient with enhanced S-cone syndrome. Japanese Journal of Ophthalmology. PMID 27522502 DOI: 10.1007/s10384-016-0470-0  0.104
2011 Iwata T, Konishi K, Yamazaki T, Kitamura K, Katagiri A, Muramoto T, Kubota Y, Yano Y, Kobayashi Y, Yamochi T, Ohike N, Murakami M, Gokan T, Yoshikawa N, Imawari M. Right colon cancer presenting as hemorrhagic shock. World Journal of Gastrointestinal Pathophysiology. 2: 15-8. PMID 21607161 DOI: 10.4291/wjgp.v2.i1.15  0.104
2023 Sato K, Inoue J, Ninomiya M, Iwata T, Sano A, Tsuruoka M, Onuki M, Sawahashi S, Ouchi K, Masamune A. Effectiveness of tacrolimus in a case of immune checkpoint inhibitor-induced hepatotoxicity that was refractory to steroids and mycophenolate mofetil. Clinical Journal of Gastroenterology. PMID 37480423 DOI: 10.1007/s12328-023-01832-8  0.104
2002 Iwata T, Morotome Y, Tanabe T, Fukae M, Ishikawa I, Oida S. Noggin blocks osteoinductive activity of porcine enamel extracts. Journal of Dental Research. 81: 387-91. PMID 12097429 DOI: 10.1177/0810387  0.103
2007 Iwata T, Yamada S, Mizusawa N, Golam HM, Sano T, Yoshimoto K. The aryl hydrocarbon receptor-interacting protein gene is rarely mutated in sporadic GH-secreting adenomas. Clinical Endocrinology. 66: 499-502. PMID 17371465 DOI: 10.1111/j.1365-2265.2007.02758.x  0.103
2019 Mizobuchi K, Hayashi T, Katagiri S, Yoshitake K, Fujinami K, Yang L, Kuniyoshi K, Shinoda K, Machida S, Kondo M, Ueno S, Terasaki H, Matsuura T, Tsunoda K, Iwata T, et al. Characterization of GUCA1A-associated dominant cone/cone-rod dystrophy: low prevalence among Japanese patients with inherited retinal dystrophies. Scientific Reports. 9: 16851. PMID 31728034 DOI: 10.1038/s41598-019-52660-1  0.103
2018 Katagiri S, Hayashi T, Mizobuchi K, Yoshitake K, Iwata T, Nakano T. Autosomal dominant retinitis pigmentosa with macular involvement associated with a disease haplotype that included a novel PRPH2 variant (p.Cys250Gly). Ophthalmic Genetics. 39: 357-365. PMID 29630435 DOI: 10.1080/13816810.2018.1459737  0.103
2008 Iwata T, Philipovskiy A, Fisher AJ, Presson RG, Chiyo M, Lee J, Mickler E, Smith GN, Petrache I, Brand DB, Burlingham WJ, Gopalakrishnan B, Greenspan DS, Christie JD, Wilkes DS. Anti-type V collagen humoral immunity in lung transplant primary graft dysfunction. Journal of Immunology (Baltimore, Md. : 1950). 181: 5738-47. PMID 18832733 DOI: 10.4049/Jimmunol.181.8.5738  0.103
2012 Iwata T, Nishiyama N, Nagano K, Izumi N, Tsukioka T, Chung K, Hanada S, Inoue K, Kaji M, Suehiro S. Preoperative serum value of sialyl Lewis X predicts pathological nodal extension and survival in patients with surgically treated small cell lung cancer. Journal of Surgical Oncology. 105: 818-24. PMID 22170474 DOI: 10.1002/jso.23002  0.103
2020 Saotome K, Chiyoda T, Aimono E, Nakamura K, Tanishima S, Nohara S, Okada C, Hayashi H, Kuroda Y, Nomura H, Susumu N, Iwata T, Yamagami W, Kataoka F, Nishihara H, et al. Clinical implications of next-generation sequencing-based panel tests for malignant ovarian tumors. Cancer Medicine. PMID 32813918 DOI: 10.1002/cam4.3383  0.103
2017 Fiorentino A, Fujinami K, Arno G, Robson AG, Pontikos N, Arasanz Armengol M, Plagnol V, Hayashi T, Iwata T, Parker M, Fowler T, Rendon A, Gardner JC, Henderson RH, Cheetham ME, et al. Missense variants in the X-linked gene PRPS1 cause retinal degeneration in females. Human Mutation. PMID 28967191 DOI: 10.1002/Humu.23349  0.103
2023 Buranasin P, Kominato H, Mizutani K, Mikami R, Saito N, Takeda K, Iwata T. Influence of Reactive Oxygen Species on Wound Healing and Tissue Regeneration in Periodontal and Peri-Implant Tissues in Diabetic Patients. Antioxidants (Basel, Switzerland). 12. PMID 37760090 DOI: 10.3390/antiox12091787  0.103
2008 Chiyo M, Iwata T, Webb TJ, Vasko MR, Thompson EL, Heidler KM, Cummings OW, Yoshida S, Fujisawa T, Brand DD, Wilkes DS. Silencing S1P1 receptors regulates collagen-V reactive lymphocyte-mediated immunobiology in the transplanted lung. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 8: 537-46. PMID 18294150 DOI: 10.1111/J.1600-6143.2007.02116.X  0.103
1996 Hashimoto S, Tsukada S, Matsushita M, Miyawaki T, Niida Y, Yachie A, Kobayashi S, Iwata T, Hayakawa H, Matsuoka H, Tsuge I, Yamadori T, Kunikata T, Arai S, Yoshizaki K, et al. Identification of Bruton's tyrosine kinase (Btk) gene mutations and characterization of the derived proteins in 35 X-linked agammaglobulinemia families: a nationwide study of Btk deficiency in Japan. Blood. 88: 561-73. PMID 8695804  0.103
2013 Kim YH, Nishimura T, Ozasa H, Nagai H, Sakamori Y, Iwata T, Sunadome H, Nishimura T, Mishima M. Phase II study of pemetrexed and erlotinib in pretreated nonsquamous, non-small-cell lung cancer patients without an EGFR mutation. Chemotherapy. 59: 414-9. PMID 25034625 DOI: 10.1159/000363731  0.103
2009 Yoshikawa K, Shimada M, Miyamoto H, Higashijima J, Miyatani T, Nishioka M, Kurita N, Iwata T, Uehara H. Sonic hedgehog relates to colorectal carcinogenesis. Journal of Gastroenterology. 44: 1113-7. PMID 19662327 DOI: 10.1007/s00535-009-0110-2  0.102
2012 Iwata T, Nishiyama N, Nagano K, Izumi N, Mizuguchi S, Tsukioka T, Morita R, Chung K, Hanada S, Inoue K. Role of pulmonary resection in the diagnosis and treatment of limited-stage small cell lung cancer: revision of clinical diagnosis based on findings of resected specimen and its influence on survival. General Thoracic and Cardiovascular Surgery. 60: 43-52. PMID 22237738 DOI: 10.1007/s11748-011-0847-4  0.102
2012 Nakagawa T, Shimada M, Kurita N, Iwata T, Nishioka M, Yoshikawa K, Higashijima J, Utsunomiya T. Thymidylate synthase (TS) protein expression as a prognostic factor in advanced colorectal cancer: a comparison with TS mRNA expression. Hepato-Gastroenterology. 59: 1059-62. PMID 22580655 DOI: 10.5754/hge09243  0.102
2023 Iwata T, Watanabe-Yanai A, Tamamura-Andoh Y, Arai N, Akiba M, Kusumoto M. Tryptanthrin Reduces Campylobacter jejuni Colonization in the Chicken Gut by a Bactericidal Mechanism. Applied and Environmental Microbiology. e0170122. PMID 36651742 DOI: 10.1128/aem.01701-22  0.102
2014 Katagiri S, Hayashi T, Yoshitake K, Akahori M, Ikeo K, Gekka T, Tsuneoka H, Iwata T. Novel C8orf37 Mutations in Patients with Early-onset Retinal Dystrophy, Macular Atrophy, Cataracts, and High Myopia. Ophthalmic Genetics. 1-8. PMID 25113443 DOI: 10.3109/13816810.2014.949380  0.102
2006 Kim JW, Yamakoshi Y, Iwata T, Hu YY, Zhang H, Hu JC, Simmer JP. Porcine dentin matrix protein 1: gene structure, cDNA sequence, and expression in teeth. European Journal of Oral Sciences. 114: 33-41. PMID 16460339 DOI: 10.1111/j.1600-0722.2006.00284.x  0.102
2012 Reissig L, Iwata T, Kikukawa T, Demura M, Kamo N, Kandori H, Sudo Y. Influence of halide binding on the hydrogen bonding network in the active site of Salinibacter sensory rhodopsin I. Biochemistry. 51: 8802-13. PMID 23062114 DOI: 10.1021/bi3009592  0.102
2009 Yamamoto A, Iwata T, Sato Y, Matsuoka D, Tokutomi S, Kandori H. Light signal transduction pathway from flavin chromophore to the J alpha helix of Arabidopsis phototropin1. Biophysical Journal. 96: 2771-8. PMID 19348760 DOI: 10.1016/j.bpj.2008.12.3924  0.102
2021 Sekito T, Takamoto A, Kobayashi Y, Mitsui M, Watari S, Kubota R, Sadahira T, Iwata T, Nishimura S, Edamura K, Sako T, Araki M, Watanabe M, Watanabe T, Shibata R, et al. A Case of Metastatic Fumarate Hydratase-Deficient-like Renal Cell Carcinoma Successfully Managed by Ipilimumab plus Nivolumab. Acta Medica Okayama. 75: 397-402. PMID 34176946 DOI: 10.18926/AMO/62237  0.102
2002 Honma M, Namikawa K, Mansur K, Iwata T, Mori N, Iizuka H, Kiyama H. Developmental alteration of nerve injury induced glial cell line-derived neurotrophic factor (GDNF) receptor expression is crucial for the determination of injured motoneuron fate. Journal of Neurochemistry. 82: 961-75. PMID 12358802 DOI: 10.1046/J.1471-4159.2002.01043.X  0.102
2015 Kondo Y, Kimura O, Tanaka Y, Ninomiya M, Iwata T, Kogure T, Inoue J, Sugiyama M, Morosawa T, Fujisaka Y, Shimosegawa T. Differential Expression of CX3CL1 in Hepatitis B Virus-Replicating Hepatoma Cells Can Affect the Migration Activity of CX3CR1+ Immune Cells. Journal of Virology. 89: 7016-27. PMID 25926643 DOI: 10.1128/JVI.00716-15  0.102
2015 Fujii T, Saito M, Hasegawa T, Iwata T, Kuramoto H, Kubushiro K, Ohmura M, Ochiai K, Arai H, Sakamoto M, Motoyama T, Aoki D. Performance of p16INK4a/Ki-67 immunocytochemistry for identifying CIN2+ in atypical squamous cells of undetermined significance and low-grade squamous intraepithelial lesion specimens: a Japanese Gynecologic Oncology Group study. International Journal of Clinical Oncology. 20: 134-42. PMID 24744261 DOI: 10.1007/s10147-014-0688-0  0.102
2008 Nakashima A, Kawamoto T, Honda KK, Ueshima T, Noshiro M, Iwata T, Fujimoto K, Kubo H, Honma S, Yorioka N, Kohno N, Kato Y. DEC1 modulates the circadian phase of clock gene expression. Molecular and Cellular Biology. 28: 4080-92. PMID 18411297 DOI: 10.1128/MCB.02168-07  0.102
1997 Iwata T, Minucci S, McGowan M, Carper D. Gene regulation of aldose reductase under osmotic stress. Advances in Experimental Medicine and Biology. 414: 507-14. PMID 9059656 DOI: 10.1007/978-1-4615-5871-2_57  0.102
1996 Kobayashi S, Iwata T, Saito M, Iwasaki R, Matsumoto H, Naritaka S, Kono Y, Hayashi Y. Mutations of the Btk gene in 12 unrelated families with X-linked agammaglobulinemia in Japan. Human Genetics. 97: 424-30. PMID 8834236  0.102
2019 Kardoust Parizi M, Iwata T, Kimura S, Janisch F, Abufaraj M, Karakiewicz PI, Enikeev D, Rapoport LM, Hutterer G, Shariat SF. Focal Neuroendocrine Differentiation of Conventional Prostate Adenocarcinoma as a Prognostic Factor after Radical Prostatectomy: A Systematic Review and Meta-Analysis. International Journal of Molecular Sciences. 20. PMID 30893781 DOI: 10.3390/ijms20061374  0.102
2006 Nagano T, Oida S, Suzuki S, Iwata T, Yamakoshi Y, Ogata Y, Gomi K, Arai T, Fukae M. Porcine enamel protein fractions contain transforming growth factor-beta1. Journal of Periodontology. 77: 1688-94. PMID 17032111 DOI: 10.1902/jop.2006.050352  0.101
2009 Izumi N, Nishiyama N, Iwata T, Nagano K, Tsukioka T, Hanada S, Suehiro S. Primary pulmonary meningioma presenting with hemoptysis on exertion. The Annals of Thoracic Surgery. 88: 647-8. PMID 19632430 DOI: 10.1016/j.athoracsur.2008.12.058  0.101
2020 Shimohira T, Katagiri S, Ohsugi Y, Hirota T, Hatasa M, Mizutani K, Watanabe K, Niimi H, Iwata T, Aoki A. Comprehensive and Sequential Gene Expression Analysis of Bone Healing Process Following Er:YAG Laser Ablation. Photobiomodulation, Photomedicine, and Laser Surgery. PMID 33347788 DOI: 10.1089/photob.2020.4833  0.101
1999 Iwata T, Sato S, Jimenez J, McGowan M, Moroni M, Dey A, Ibaraki N, Reddy VN, Carper D. Osmotic response element is required for the induction of aldose reductase by tumor necrosis factor-alpha. The Journal of Biological Chemistry. 274: 7993-8001. PMID 10075698 DOI: 10.1074/jbc.274.12.7993  0.101
2010 Okamoto H, Umeda S, Nozawa T, Suzuki MT, Yoshikawa Y, Matsuura ET, Iwata T. Comparative proteomic analyses of macular and peripheral retina of cynomolgus monkeys (Macaca fascicularis). Experimental Animals / Japanese Association For Laboratory Animal Science. 59: 171-82. PMID 20484850 DOI: JST.JSTAGE/expanim/59.171  0.101
2022 Pan Y, Fu Y, Baird PN, Guymer RH, Das T, Iwata T. Exploring the contribution of ARMS2 and HTRA1 genetic risk factors in age-related macular degeneration. Progress in Retinal and Eye Research. 101159. PMID 36581531 DOI: 10.1016/j.preteyeres.2022.101159  0.101
1983 Aki T, Nakamura T, Ichikizaki K, Iwata T, Toya S, Nakano S. [A case of primary malignant lymphoma of the brain which showed a remarkable response to prednisolone]. No to Shinkei = Brain and Nerve. 34: 965-71. PMID 7150452  0.101
2020 Fujinami-Yokokawa Y, Fujinami K, Kuniyoshi K, Hayashi T, Ueno S, Mizota A, Shinoda K, Arno G, Pontikos N, Yang L, Liu X, Sakuramoto H, Katagiri S, Mizobuchi K, Kominami T, ... ... Iwata T, et al. Clinical and Genetic Characteristics of 18 Patients from 13 Japanese Families with CRX-associated retinal disorder: Identification of Genotype-phenotype Association. Scientific Reports. 10: 9531. PMID 32533067 DOI: 10.1038/s41598-020-65737-z  0.101
2011 Hara K, Akahori M, Tanito M, Kaidzu S, Ohira A, Iwata T. Analysis of LOXL1 gene variants in Japanese patients with branch retinal vein occlusion. Molecular Vision. 17: 3309-13. PMID 22194657  0.101
2020 Owen LA, Shirer K, Collazo SA, Szczotka K, Baker S, Wood B, Carroll L, Haaland B, Iwata T, Katikaneni LD, DeAngelis MM. The Serine Protease HTRA-1 Is a Biomarker for ROP and Mediates Retinal Neovascularization. Frontiers in Molecular Neuroscience. 13: 605918. PMID 33281553 DOI: 10.3389/fnmol.2020.605918  0.101
2019 Gan YJ, Fang AW, Liu C, Liu BJ, Yang FM, Guan JT, Lan CL, Dai XD, Li T, Cao Y, Ran Y, Gong XH, Jin ZB, Cui RZ, Iwata T, et al. Elevated Plasma Levels of Drebrin in Glaucoma Patients With Neurodegeneration. Frontiers in Neuroscience. 13: 326. PMID 31001081 DOI: 10.3389/fnins.2019.00326  0.101
2013 Hanagiri T, Shigematsu Y, Shinohara S, Takenaka M, Oka S, Chikaishi Y, Nagata Y, Iwata T, Uramoto H, So T, Tanaka F. Clinical significance of the frequency of regulatory T cells in regional lymph node lymphocytes as a prognostic factor for non-small-cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 81: 475-9. PMID 23891508 DOI: 10.1016/j.lungcan.2013.07.001  0.1
2013 Katagiri S, Yoshitake K, Akahori M, Hayashi T, Furuno M, Nishino J, Ikeo K, Tsuneoka H, Iwata T. Whole-exome sequencing identifies a novel ALMS1 mutation (p.Q2051X) in two Japanese brothers with Alström syndrome. Molecular Vision. 19: 2393-406. PMID 24319333  0.1
1981 Iwata T, Incefy GS, Cunningham-Rundles S, Cunningham-Rundles C, Smithwick E, Geller N, O'Reilly R, Good RA. Circulating thymic hormone activity in patients with primary and secondary immunodeficiency diseases. The American Journal of Medicine. 71: 385-94. PMID 7197118 DOI: 10.1016/0002-9343(81)90164-9  0.1
1985 Yamashita Y, Okuzono Y, Yokota T, Takahashi M, Ishihara T, Uchino F, Kamei T, Adachi H, Iwata T, Matsumoto N. Morphologic study of three cases of insulinoma. Histochemical and ultrastructural studies. Cancer. 55: 841-7. PMID 2981604 DOI: 10.1002/1097-0142(19850215)55:4<841::aid-cncr2820550422>3.0.co;2-q  0.1
2001 Nakata K, Yamasaki M, Iwata T, Suzuki K, Nakane A, Nakamura H. Anaerobic bacterial extracts influence production of matrix metalloproteinases and their inhibitors by human dental pulp cells. Journal of Endodontics. 26: 410-3. PMID 11199767 DOI: 10.1097/00004770-200007000-00008  0.1
2019 Motoike S, Kajiya M, Komatsu N, Horikoshi S, Ogawa T, Sone H, Matsuda S, Ouhara K, Iwata T, Mizuno N, Fujita T, Ikeya M, Kurihara H. Clumps of Mesenchymal Stem Cell/Extracellular Matrix Complexes Generated with Xeno-Free Conditions Facilitate Bone Regeneration via Direct and Indirect Osteogenesis. International Journal of Molecular Sciences. 20. PMID 31443173 DOI: 10.3390/ijms20163970  0.1
2007 Fujita T, Iwata T, Shiba H, Igarashi A, Hirata R, Takeda K, Mizuno N, Tsuji K, Kawaguchi H, Kato Y, Kurihara H. Identification of marker genes distinguishing human periodontal ligament cells from human mesenchymal stem cells and human gingival fibroblasts. Journal of Periodontal Research. 42: 283-6. PMID 17451549 DOI: 10.1111/j.1600-0765.2006.00944.x  0.1
2020 Sano K, Usui M, Moritani Y, Nakazawa K, Hanatani T, Kondo H, Nakatomi M, Onizuka S, Iwata T, Sato T, Togari A, Ariyoshi W, Nishihara T, Nakashima K. Co-cultured spheroids of human periodontal ligament mesenchymal stem cells and vascular endothelial cells enhance periodontal tissue regeneration. Regenerative Therapy. 14: 59-71. PMID 31988996 DOI: 10.1016/j.reth.2019.12.008  0.1
2016 Mizuguchi S, Iwata T, Izumi N, Tsukioka T, Hanada S, Komatsu H, Nishiyama N. Arterial blood gases predict long-term prognosis in stage I non-small cell lung cancer patients. Bmc Surgery. 16: 3. PMID 26976126 DOI: 10.1186/s12893-016-0119-4  0.1
2014 Washio K, Kuroda H, Iwata T, Yoshida T, Yamato M, Okano T. Improved enzymatic treatment for accurate cell counting from extracellular matrix-rich periodontal ligament cell sheets. The International Journal of Oral & Maxillofacial Implants. 29: e117-21. PMID 24451879  0.1
2012 Tsunoda K, Usui T, Hatase T, Yamai S, Fujinami K, Hanazono G, Shinoda K, Ohde H, Akahori M, Iwata T, Miyake Y. Clinical characteristics of occult macular dystrophy in family with mutation of RP1l1 gene. Retina (Philadelphia, Pa.). 32: 1135-47. PMID 22466457 DOI: 10.1097/IAE.0b013e318232c32e  0.1
2018 Yamamuro T, Inoue K, Nagai Y, Azuma D, Yamamoto A, Hara K, Kohara M, Iwata T, Nakatsuka S, Morii E, Yamamoto T. A case of ectopic ACTH syndrome due to DDAVP-sensitive but V1b receptor-negative bronchial typical carcinoid with lymphatic metastasis and plasma ProGRP elevation. Endocrine Journal. PMID 30232300 DOI: 10.1507/endocrj.EJ18-0052  0.099
2013 Takasu C, Shimada M, Kurita N, Iwata T, Sato H, Nishioka M, Morimoto S, Yoshikawa K, Miyatani T, Kashihara H, Utsunomiya T, Uehara H. Survivin expression can predict the effect of chemoradiotherapy for advanced lower rectal cancer. International Journal of Clinical Oncology. 18: 869-76. PMID 22936565 DOI: 10.1007/s10147-012-0470-0  0.099
2021 Oishi A, Fujinami K, Mawatari G, Naoi N, Ikeda Y, Ueno S, Kuniyoshi K, Hayashi T, Kondo H, Mizota A, Shinoda K, Kusuhara S, Nakamura M, Iwata T, Tsujikawa A, et al. Genetic and Phenotypic Landscape of -Associated Retinal Dystrophy in Japan. Genes. 12. PMID 34828423 DOI: 10.3390/genes12111817  0.099
2020 Mikami R, Mizutani K, Gohda T, Gotoh H, Matsuyama Y, Aoyama N, Matsuura T, Kido D, Takeda K, Izumi Y, Fujiwara T, Iwata T. Association between circulating tumor necrosis factor receptors and oral bacterium in patients receiving hemodialysis: a cross-sectional study. Clinical and Experimental Nephrology. PMID 32816134 DOI: 10.1007/S10157-020-01952-2  0.099
2020 Ohsugi Y, Niimi H, Shimohira T, Hatasa M, Katagiri S, Aoki A, Iwata T. In Vitro Cytological Responses against Laser Photobiomodulation for Periodontal Regeneration. International Journal of Molecular Sciences. 21. PMID 33256246 DOI: 10.3390/ijms21239002  0.099
1984 Morihara K, Tsuzuki H, Harada M, Iwata T. Purification of human plasma alpha 1-proteinase inhibitor and its inactivation by Pseudomonas aeruginosa elastase. Journal of Biochemistry. 95: 795-804. PMID 6427201 DOI: 10.1093/oxfordjournals.jbchem.a134671  0.099
2016 Kuji S, Watanabe R, Sato Y, Iwata T, Hirashima Y, Takekuma M, Ito I, Abe M, Nagashio R, Omae K, Aoki D, Kameya T. A new marker, insulinoma-associated protein 1 (INSM1), for high-grade neuroendocrine carcinoma of the uterine cervix: Analysis of 37 cases. Gynecologic Oncology. PMID 27908529 DOI: 10.1016/j.ygyno.2016.11.020  0.099
1976 Iwata T, Ohkawa K, Uyama M. The fine structural localization of peroxidase activity in goblet cells of the conjunctival epithelium of rats. Investigative Ophthalmology. 15: 40-4. PMID 1245379  0.099
2007 Mizuguchi S, Nishiyama N, Iwata T, Nishida T, Izumi N, Tsukioka T, Inoue K, Uenishi T, Wakasa K, Suehiro S. Serum Sialyl Lewis x and cytokeratin 19 fragment as predictive factors for recurrence in patients with stage I non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 58: 369-75. PMID 17697728 DOI: 10.1016/J.LUNGCAN.2007.07.002  0.099
2000 Yamamoto K, Takahashi N, Nakai T, Miura S, Shioda A, Iwata T, Kouki T, Kobayashi T, Kikuyama S. Production of a recombinant newt growth hormone and its application for the development of a radioimmunoassay. General and Comparative Endocrinology. 117: 103-16. PMID 10620427 DOI: 10.1006/gcen.1999.7387  0.099
2019 Mawatari G, Fujinami K, Liu X, Yang L, Yokokawa YF, Komori S, Ueno S, Terasaki H, Katagiri S, Hayashi T, Kuniyoshi K, Miyake Y, Tsunoda K, Yoshitake K, Iwata T, et al. Clinical and genetic characteristics of 14 patients from 13 Japanese families with -associated retinal disorder: report of eight novel variants. Human Genome Variation. 6: 34. PMID 31645972 DOI: 10.1038/s41439-019-0065-7  0.098
2012 Chen CJ, Scholl HP, Birch DG, Iwata T, Miller NR, Goldberg MF. Characterizing the phenotype and genotype of a family with occult macular dystrophy. Archives of Ophthalmology (Chicago, Ill. : 1960). 130: 1554-9. PMID 23229695 DOI: 10.1001/Archophthalmol.2012.2683  0.098
1998 Hirai T, Yoshimoto A, Iwata T, Yamashita Y, Kuwahara M, Toge T. Enhancing effect of thoraco-laparotomy on liver metastasis and the role played by active oxygens in its mechanism. Surgery Today. 27: 1040-5. PMID 9413057 DOI: 10.1007/BF02385785  0.098
2015 Iwata T, Ito I, Niimi A, Ikegami K, Marumo S, Tanabe N, Nakaji H, Kanemitsu Y, Matsumoto H, Kamei J, Setou M, Mishima M. Mechanical Stimulation by Postnasal Drip Evokes Cough. Plos One. 10: e0141823. PMID 26581078 DOI: 10.1371/journal.pone.0141823  0.098
1990 Frohlich ED, Iwata T, Sasaki O. Clinical and physiologic significance of local tissue renin-angiotensin systems. The American Journal of Medicine. 87: 19S-23S. PMID 2690610 DOI: 10.1016/0002-9343(89)90086-7  0.098
2016 Kamata T, Yoshida S, Wada H, Fujiwara T, Suzuki H, Nakajima T, Iwata T, Nakatani Y, Yoshino I. Extrathymic malignancies associated with thymoma: a forty-year experience at a single institution. Interactive Cardiovascular and Thoracic Surgery. PMID 28040768 DOI: 10.1093/icvts/ivw354  0.098
2020 Ohno A, Iwata T, Katoh Y, Taniguchi S, Tanaka K, Nishio H, Nakamura M, Morisada T, Chen G, Saito M, Yaguchi T, Kawakami Y, Aoki D. Tumor-infiltrating lymphocytes predict survival outcomes in patients with cervical cancer treated with concurrent chemoradiotherapy. Gynecologic Oncology. PMID 32829964 DOI: 10.1016/j.ygyno.2020.07.106  0.098
2023 Kogure G, Tanaka K, Matsui T, Onuki M, Matsumoto K, Iwata T, Kukimoto I. Intra-Patient Genomic Variations of Human Papillomavirus Type 31 in Cervical Cancer and Precancer. Viruses. 15. PMID 37896881 DOI: 10.3390/v15102104  0.098
2008 Iwata T, Chiyo M, Yoshida S, Smith GN, Mickler EA, Presson R, Fisher AJ, Brand DD, Cummings OW, Wilkes DS. Lung transplant ischemia reperfusion injury: metalloprotease inhibition down-regulates exposure of type V collagen, growth-related oncogene-induced neutrophil chemotaxis, and tumor necrosis factor-alpha expression. Transplantation. 85: 417-26. PMID 18322435 DOI: 10.1097/Tp.0B013E31815E91B6  0.097
2009 Hiroshima K, Yusa T, Kameya T, Ito I, Kaneko K, Kadoyama C, Kishi H, Saitoh Y, Ozaki D, Itami M, Iwata T, Iyoda A, Kawai T, Yoshino I, Nakatani Y. Malignant pleural mesothelioma: clinicopathology of 16 extrapleural pneumonectomy patients with special reference to early stage features. Pathology International. 59: 537-45. PMID 19627537 DOI: 10.1111/j.1440-1827.2009.02404.x  0.097
1990 Mochizuki Y, Iwata T, Oida K, Kohri Y, Taguchi Y, Nanbu Y, Tomii K, Kubo Y, Yuba Y, Ichijima K. [A clinical study of terminal pneumonia]. Nihon Kyobu Shikkan Gakkai Zasshi. 27: 310-6. PMID 2515333  0.097
2021 Nagahara T, Takeda K, Inoue S, Wada K, Shirawachi S, Iwata T, Shiba H. Endodontic Approach and Periodontal Regenerative Therapy for a Mandibular Right Central Incisor Affected by a Perforation and Cemental Tear. The International Journal of Periodontics & Restorative Dentistry. 41: e205-e212. PMID 34547073 DOI: 10.11607/prd.5466  0.097
2022 Sone H, Kajiya M, Takeda K, Sasaki S, Horikoshi S, Motoike S, Morimoto S, Yoshii H, Yoshino M, Iwata T, Ouhara K, Matsuda S, Mizuno N. Clumps of mesenchymal stem cells/extracellular matrix complexes directly reconstruct the functional periodontal tissue in a rat periodontal defect model. Journal of Tissue Engineering and Regenerative Medicine. PMID 35951352 DOI: 10.1002/term.3343  0.097
2017 Matsuo K, Shimada M, Yamaguchi S, Kanao H, Nakanishi T, Saito T, Kamiura S, Iwata T, Mikami M, Sugiyama T. Identifying a candidate population for ovarian conservation in young women with clinical stage IB-IIB cervical cancer. International Journal of Cancer. PMID 28975603 DOI: 10.1002/ijc.31084  0.097
2011 Koh CM, Iwata T, Zheng Q, Bethel C, Yegnasubramanian S, De Marzo AM. Myc enforces overexpression of EZH2 in early prostatic neoplasia via transcriptional and post-transcriptional mechanisms. Oncotarget. 2: 669-83. PMID 21941025 DOI: 10.18632/Oncotarget.327  0.097
2018 Iwata T, Yamato M, Washio K, Yoshida T, Tsumanuma Y, Yamada A, Onizuka S, Izumi Y, Ando T, Okano T, Ishikawa I. Periodontal regeneration with autologous periodontal ligament-derived cell sheets - A safety and efficacy study in ten patients. Regenerative Therapy. 9: 38-44. PMID 30525074 DOI: 10.1016/j.reth.2018.07.002  0.097
1998 Shuba YM, Iwata T, Naidenov VG, Oz M, Sandberg K, Kraev A, Carafoli E, Morad M. A novel molecular determinant for cAMP-dependent regulation of the frog heart Na+-Ca2+ exchanger. The Journal of Biological Chemistry. 273: 18819-25. PMID 9668056 DOI: 10.1074/jbc.273.30.18819  0.096
2006 Chun YH, Yamakoshi Y, Kim JW, Iwata T, Hu JC, Simmer JP. Porcine SPARC: isolation from dentin, cDNA sequence, and computer model. European Journal of Oral Sciences. 114: 78-85; discussion 93. PMID 16674666 DOI: 10.1111/j.1600-0722.2006.00280.x  0.096
2017 Kaibuchi N, Iwata T, Onizuka S, Yano K, Yamato M, Okano T, Ando T. Cytological character of mini pig mesenchymal stromal cells from various tissues and the attempt of cell sheet formation. Regenerative Therapy. 6: 83-89. PMID 30271842 DOI: 10.1016/j.reth.2017.02.001  0.096
2014 Ohkuma Y, Hayashi T, Sakai T, Watanabe A, Yamada H, Akahori M, Itabashi T, Iwata T, Noda T, Tsuneoka H. Retinal angiomatous proliferation associated with risk alleles of ARMS2/HTRA1 gene polymorphisms in Japanese patients. Clinical Ophthalmology (Auckland, N.Z.). 8: 143-8. PMID 24403817 DOI: 10.2147/OPTH.S56483  0.096
2016 Kuniyoshi K, Muraki-Oda S, Ueyama H, Toyoda F, Sakuramoto H, Ogita H, Irifune M, Yamamoto S, Nakao A, Tsunoda K, Iwata T, Ohji M, Shimomura Y. Novel mutations in the gene for α-subunit of retinal cone cyclic nucleotide-gated channels in a Japanese patient with congenital achromatopsia. Japanese Journal of Ophthalmology. PMID 27040408 DOI: 10.1007/s10384-016-0424-6  0.096
2003 Kodama-Takahashi K, Kurata A, Ohshima K, Yamamoto K, Uemura S, Watanabe S, Iwata T. Effect of cilostazol on the ventricular escape rate and neurohumoral factors in patients with third-degree atrioventricular block. Chest. 123: 1161-9. PMID 12684307 DOI: 10.1378/chest.123.4.1161  0.096
1998 Inoue K, Yamamoto R, Nishiyama N, Hori T, Miyamoto Y, Takehara S, Kaji M, Kin T, Katoh T, Iwata T, Nishida T, Kinoshita H. A case of pulmonary metastases of synovial sarcoma surviving for a long period after active surgery. Osaka City Medical Journal. 44: 125-31. PMID 9834625  0.096
2000 Mukae S, Aoki S, Itoh S, Iwata T, Ueda H, Katagiri T. Bradykinin B(2) receptor gene polymorphism is associated with angiotensin-converting enzyme inhibitor-related cough. Hypertension (Dallas, Tex. : 1979). 36: 127-31. PMID 10904024 DOI: 10.1161/01.hyp.36.1.127  0.096
2015 Yamada D, Yamamoto J, Zhang Y, Iwata T, Hitomi K, Getzoff ED, Iwai S, Kandori H. Structural Changes of the Active Center during the Photoactivation of Xenopus (6-4) Photolyase. Biochemistry. PMID 26719910 DOI: 10.1021/Acs.Biochem.5B01111  0.096
2023 Nishimura T, Makigawa S, Sun J, Kodama K, Sugiyama H, Matsumoto K, Iwata T, Wasano N, Kano A, Morita MT, Fujii Y, Shindo M. Design and synthesis of strong root gravitropism inhibitors with no concomitant growth inhibition. Scientific Reports. 13: 5173. PMID 36997582 DOI: 10.1038/s41598-023-32063-z  0.096
2021 Iwata T, Tomeoka S, Hirota J. A class I odorant receptor enhancer shares a functional motif with class II enhancers. Scientific Reports. 11: 510. PMID 33436797 DOI: 10.1038/s41598-020-79980-x  0.096
2014 Ouhara K, Savitri IJ, Fujita T, Kittaka M, Kajiya M, Iwata T, Miyagawa T, Yamakawa M, Shiba H, Kurihara H. miR-584 expressed in human gingival epithelial cells is induced by Porphyromonas gingivalis stimulation and regulates interleukin-8 production via lactoferrin receptor. Journal of Periodontology. 85: e198-204. PMID 24228808 DOI: 10.1902/jop.2013.130335  0.096
2006 Iwata T, Murata M, Hirose M, Shimada K. [Cholesterol pericarditis identified by increased cardiothoracic ratio on chest radiography: a case report]. Journal of Cardiology. 48: 221-6. PMID 17066626  0.096
2019 Taga H, Hosokawa Y, Manabe T, Hagiwara N, Yamada T, Iwata T, Miyashita H. [A Case of Primary Testicular Mucinous Carcinoma]. Hinyokika Kiyo. Acta Urologica Japonica. 65: 87-91. PMID 31067849 DOI: 10.14989/ActaUrolJap_65_3_87  0.095
1988 Inui K, Saito H, Iwata T, Hori R. Aminoglycoside-induced alterations in apical membranes of kidney epithelial cell line (LLC-PK1). The American Journal of Physiology. 254: C251-7. PMID 3126664 DOI: 10.1152/ajpcell.1988.254.2.C251  0.095
2019 Nakamura M, Ueda M, Iwata T, Kiguchi K, Mikami Y, Kakuma T, Aoki D. A Clinical Trial to Verify the Efficiency of the LC-1000 Exfoliative Cell Analyzer as a New Method of Cervical Cancer Screening. Acta Cytologica. 1-10. PMID 31216550 DOI: 10.1159/000501118  0.095
2020 Suzuki T, Otsuka M, Seimiya T, Iwata T, Kishikawa T, Koike K. The biological role of metabolic reprogramming in pancreatic cancer. Medcomm. 1: 302-310. PMID 34766124 DOI: 10.1002/mco2.37  0.095
2021 Hayashi T, Mizobuchi K, Kameya S, Yoshitake K, Iwata T, Nakano T. A new PDE6A missense variant p.Arg544Gln in rod-cone dystrophy. Documenta Ophthalmologica. Advances in Ophthalmology. PMID 33611760 DOI: 10.1007/s10633-021-09826-y  0.095
2017 Kato D, Yaguchi T, Iwata T, Morii K, Nakagawa T, Nishimura R, Kawakami Y. Prospects for personalized combination immunotherapy for solid tumors based on adoptive cell therapies and immune checkpoint blockade therapies. Nihon Rinsho Men'Eki Gakkai Kaishi = Japanese Journal of Clinical Immunology. 40: 68-77. PMID 28539557 DOI: 10.2177/jsci.40.68  0.095
2021 Nemoto T, Shiba T, Komatsu K, Watanabe T, Shimogishi M, Shibasaki M, Koyanagi T, Nagai T, Katagiri S, Takeuchi Y, Iwata T. Discrimination of Bacterial Community Structures among Healthy, Gingivitis, and Periodontitis Statuses through Integrated Metatranscriptomic and Network Analyses. Msystems. 6: e0088621. PMID 34698525 DOI: 10.1128/mSystems.00886-21  0.095
2005 Okada T, Noji S, Goto Y, Iwata T, Fujita T, Okada T, Matsuzaki Y, Kuwana M, Hirakata M, Horii A, Matsuno S, Sunamura M, Kawakami Y. Immune responses to DNA mismatch repair enzymes hMSH2 and hPMS1 in patients with pancreatic cancer, dermatomyositis and polymyositis. International Journal of Cancer. 116: 925-33. PMID 15856462 DOI: 10.1002/ijc.21118  0.095
2012 Okamoto T, Iwata T, Mizobuchi T, Hoshino H, Moriya Y, Yoshida S, Yoshino I. Pulmonary resection for lung cancer with malignant pleural disease first detected at thoracotomy. European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association For Cardio-Thoracic Surgery. 41: 25-30. PMID 21616674 DOI: 10.1016/j.ejcts.2011.04.010  0.095
2016 Okazaki S, Hori J, Watanabe M, Hashizume K, Kobayashi S, Azumi M, Kita M, Iwata T, Matsumoto S, Kakizaki H. [Successful Management by Immunoglobulin for Sunitinib-Induced Thrombocytopenia in a Patient with Advanced Metastatic Renal Cell Carcinoma]. Hinyokika Kiyo. Acta Urologica Japonica. 62: 73-6. PMID 27018409  0.095
1999 Mukae S, Aoki S, Itoh S, Nishio K, Iwata T, Ueda H, Geshi E, Fuzimaki T, Katagiri T. Promoter polymorphism of the beta2 bradykinin receptor gene is associated with essential hypertension. Japanese Circulation Journal. 63: 759-62. PMID 10553917 DOI: 10.1253/jcj.63.759  0.095
2007 Iwata T, Nishiyama N, Inoue K, Kawata Y, Izumi N, Tsukioka T, Shinkawa K, Suehiro S. Biphasic pulmonary blastoma: report of a case. Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia. 13: 40-3. PMID 17392670  0.094
2004 Juji F, Kobayashi S, Ito S, Sugawara N, Kano H, Yasueda H, Iwata T. [Immunotherapy by Japanese cedarpollen in atpic dermatitis]. Arerugi = [Allergy]. 52: 1081-8. PMID 14685040  0.094
2010 Chi ZL, Akahori M, Obazawa M, Minami M, Noda T, Nakaya N, Tomarev S, Kawase K, Yamamoto T, Noda S, Sasaoka M, Shimazaki A, Takada Y, Iwata T. Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice. Human Molecular Genetics. 19: 2606-15. PMID 20388642 DOI: 10.1093/hmg/ddq146  0.094
2020 Mizobuchi K, Hayashi T, Yoshitake K, Fujinami K, Tachibana T, Tsunoda K, Iwata T, Nakano T. Novel homozygous CLN3 missense variant in isolated retinal dystrophy: A case report and electron microscopic findings. Molecular Genetics & Genomic Medicine. e1308. PMID 32441891 DOI: 10.1002/mgg3.1308  0.094
1986 Iwata T, Watanabe T, Kufe DW. Effects of 5-fluorouracil on globin mRNA synthesis in murine erythroleukemia cells. Biochemistry. 25: 2703-7. PMID 3459551 DOI: 10.1021/bi00357a063  0.094
2011 Tsumanuma Y, Iwata T, Washio K, Yoshida T, Yamada A, Takagi R, Ohno T, Lin K, Yamato M, Ishikawa I, Okano T, Izumi Y. Comparison of different tissue-derived stem cell sheets for periodontal regeneration in a canine 1-wall defect model. Biomaterials. 32: 5819-25. PMID 21605900 DOI: 10.1016/j.biomaterials.2011.04.071  0.094
2018 Iwata TN, Ishii C, Ishida S, Ogitani Y, Wada T, Agatsuma T. A HER2-targeting antibody-drug conjugate, trastuzumab deruxtecan (DS-8201a), enhances antitumor immunity in a mouse model. Molecular Cancer Therapeutics. PMID 29703841 DOI: 10.1158/1535-7163.MCT-17-0749  0.094
2016 Ueno S, Nakanishi A, Kominami T, Ito Y, Hayashi T, Yoshitake K, Kawamura Y, Tsunoda K, Iwata T, Terasaki H. In vivo imaging of a cone mosaic in a patient with achromatopsia associated with a GNAT2 variant. Japanese Journal of Ophthalmology. PMID 27718025 DOI: 10.1007/s10384-016-0484-7  0.094
2009 Niwase K, Nakamura KG, Yokoo M, Kondo K, Iwata T. Pathway for the transformation from highly oriented pyrolytic graphite into amorphous diamond. Physical Review Letters. 102: 116803. PMID 19392227 DOI: 10.1103/PhysRevLett.102.116803  0.094
2022 Fujino A, Fuchimoto Y, Baba Y, Isogawa N, Iwata T, Arai K, Abe M, Kanai N, Takagi R, Maeda M, Umezawa A. First-in-human autologous oral mucosal epithelial sheet transplantation to prevent anastomotic re-stenosis in congenital esophageal atresia. Stem Cell Research & Therapy. 13: 35. PMID 35090534 DOI: 10.1186/s13287-022-02710-9  0.094
2011 Zhang Z, Yang Z, Jäämaa S, Liu H, Pellakuru LG, Iwata T, af Hällström TM, De Marzo AM, Laiho M. Differential epithelium DNA damage response to ATM and DNA-PK pathway inhibition in human prostate tissue culture. Cell Cycle (Georgetown, Tex.). 10: 3545-53. PMID 22030624 DOI: 10.4161/cc.10.20.17841  0.094
2004 Iwata T, Conlon JM, Nakada T, Toyoda F, Yamamoto K, Kikuyama S. Processing of multiple forms of preprosodefrin in the abdominal gland of the red-bellied newt Cynops pyrrhogaster: regional and individual differences in preprosodefrin gene expression. Peptides. 25: 1537-43. PMID 15374655 DOI: 10.1016/j.peptides.2003.10.027  0.094
2021 Saida H, Fukuba S, Shiba T, Komatsu K, Iwata T, Nitta H. Two-stage approach for class II mandibular furcation defect with insufficient keratinized mucosa: a case report with 3 years' follow-up. The Journal of International Medical Research. 49: 3000605211044595. PMID 34528469 DOI: 10.1177/03000605211044595  0.094
2006 Tsukioka T, Inoue K, Iwata T, Mizuguchi S, Morita R, Suehiro S. Resected case of synovial sarcoma in the pleural cavity. The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association For Thoracic Surgery = Nihon Kyobu Geka Gakkai Zasshi. 54: 263-6. PMID 16813111 DOI: 10.1007/PL00022249  0.093
2020 Shindo M, Makigawa S, Kodama K, Sugiyama H, Matsumoto K, Iwata T, Wasano N, Kano A, Morita MT, Fujii Y. Design and chemical synthesis of root gravitropism inhibitors: Bridged analogues of ku-76 have more potent activity. Phytochemistry. 179: 112508. PMID 32905916 DOI: 10.1016/j.phytochem.2020.112508  0.093
1989 Iwata T, Hardee E, Frohlich ED, Cole FE. Amiloride enhances atrial natriuretic factor stimulation of cGMP accumulation in rat glomeruli. Peptides. 10: 575-9. PMID 2571140 DOI: 10.1016/0196-9781(89)90145-9  0.093
2004 Nagano T, Iwata T, Ogata Y, Tanabe T, Gomi K, Fukae M, Arai T, Oida S. Effect of heat treatment on bioactivities of enamel matrix derivatives in human periodontal ligament (HPDL) cells. Journal of Periodontal Research. 39: 249-56. PMID 15206918 DOI: 10.1111/j.1600-0765.2004.00733.x  0.093
2019 Maeda-Katahira A, Nakamura N, Hayashi T, Katagiri S, Shimizu S, Ohde H, Matsunaga T, Kaga K, Nakano T, Kameya S, Matsuura T, Fujinami K, Iwata T, Tsunoda K. Autosomal dominant optic atrophy with gene mutations accompanied by auditory neuropathy and other systemic complications in a Japanese cohort. Molecular Vision. 25: 559-573. PMID 31673222  0.093
2022 Shirai Y, Morita S, Iwata T, Nakai H, Yoshikawa M, Yoshida K, Iwamoto H, Miyaji K, Okugawa Y, Miki C, Tanaka K. Anti-inflammatory and nutritional improvement effects of dietary supplementation combined with fish oil in patients with epithelial cancer. Oncology Letters. 24: 306. PMID 35949598 DOI: 10.3892/ol.2022.13426  0.093
2015 Ogawa T, Iwata T, Kaneko S, Itaya M, Hirota J. An inducible recA expression Bacillus subtilis genome vector for stable manipulation of large DNA fragments. Bmc Genomics. 16: 209. PMID 25879542 DOI: 10.1186/s12864-015-1425-4  0.093
2006 Iwata T, Nakano H, Nakano A, Toyomaki Y, Tamai K, Tomita Y. Dominant dystrophic epidermolysis bullosa caused by a novel G2037R mutation and by a known G2028R mutation in the type VII collagen gene (COL7A1). The Journal of Dermatology. 33: 550-6. PMID 16923137 DOI: 10.1111/j.1346-8138.2006.00130.x  0.093
2007 Yamamoto A, Iwata T, Tokutomi S, Kandori H. Role of Phe1010 in light-induced structural changes of the neo1-LOV2 domain of Adiantum. Biochemistry. 47: 922-8. PMID 18163650 DOI: 10.1021/bi701851v  0.093
2006 Miyata Y, Iwata T, Maruta S, Kanda S, Nishikido M, Koga S, Kanetake H. Expression of matrix metalloproteinase-10 in renal cell carcinoma and its prognostic role. European Urology. 52: 791-7. PMID 17207914 DOI: 10.1016/j.eururo.2006.12.028  0.093
2000 Iwata T, Inoue K, Kato T, Nishida T, Kinoshita H. Induction of human gamma delta T cells in myasthenia gravis thymus transplanted SCID mice. Osaka City Medical Journal. 45: 109-21. PMID 10730077  0.093
2012 Hazawa M, Kudo M, Iwata T, Saito K, Takahashi K, Igarashi J, Suga H, Kashiwakura I. Caspase-independent apoptosis induction of quorum-sensing autoinducer analogs against chronic myeloid leukemia K562. Investigational New Drugs. 30: 862-9. PMID 21207239 DOI: 10.1007/S10637-010-9623-Z  0.093
2011 Takeda K, Sakai N, Shiba H, Nagahara T, Fujita T, Kajiya M, Iwata T, Matsuda S, Kawahara K, Kawaguchi H, Kurihara H. Characteristics of high-molecular-weight hyaluronic acid as a brain-derived neurotrophic factor scaffold in periodontal tissue regeneration. Tissue Engineering. Part A. 17: 955-67. PMID 21091323 DOI: 10.1089/ten.TEA.2010.0070  0.093
2013 Iwata T, Chiku K, Amano K, Kusumoto M, Ohnishi-Kameyama M, Ono H, Akiba M. Effects of lipooligosaccharide inner core truncation on bile resistance and chick colonization by Campylobacter jejuni. Plos One. 8: e56900. PMID 23437265 DOI: 10.1371/Journal.Pone.0056900  0.093
2002 Chiba I, Sakakibara A, Iwata TH, Ishizuka M, Tanabe S, Akahori F, Kazusaka A, Fujita S. Hepatic microsomal cytochrome p450s and chlorinated hydrocarbons in largha and ribbon seals from Hokkaido, Japan: differential response of seal species to Ah receptor agonist exposure. Environmental Toxicology and Chemistry. 21: 794-806. PMID 11951954 DOI: 10.1897/1551-5028(2002)021<0794:hmcpac>2.0.co;2  0.093
2012 Okugawa Y, Toiyama Y, Inoue Y, Iwata T, Fujikawa H, Saigusa S, Konishi N, Tanaka K, Uchida K, Kusunoki M. Clinical significance of serum soluble E-cadherin in colorectal carcinoma. The Journal of Surgical Research. 175: e67-73. PMID 22277332 DOI: 10.1016/j.jss.2011.11.009  0.093
2002 Fukui T, Kichise T, Iwata T, Doi Y. Characterization of 13 kDa granule-associated protein in Aeromonas caviae and biosynthesis of polyhydroxyalkanoates with altered molar composition by recombinant bacteria. Biomacromolecules. 2: 148-53. PMID 11749166 DOI: 10.1021/bm0056052  0.092
2004 Iwata T, Honda H, Matsuda H, Kondo M, Taniguchi J, Miwa T, Kumasaka K, Moroe H, Notoya Y. Hypothyroidism changes adrenoceptor- and muscarinic receptor-mediated blood pressure responses. European Journal of Pharmacology. 507: 311-6. PMID 15659322 DOI: 10.1016/j.ejphar.2004.11.002  0.092
2017 Kominami A, Ueno S, Kominami T, Nakanishi A, Ito Y, Fujinami K, Tsunoda K, Hayashi T, Kikuchi S, Kameya S, Iwata T, Terasaki H. Case of Cone Dystrophy with Normal Fundus Appearance Associated with Biallelic POC1B Variants. Ophthalmic Genetics. 1-8. PMID 29220607 DOI: 10.1080/13816810.2017.1408846  0.092
2019 Tanaka K, Iwata T, Yoshida S, Nishii K, Matsui Y, Sugiyama T, Itami M, Iizasa T. A surgical case of synchronous solitary splenic metastasis from lung squamous cell carcinoma: report of a case and review of the literature. General Thoracic and Cardiovascular Surgery. PMID 31845086 DOI: 10.1007/s11748-019-01275-4  0.092
2007 Iwata T, Inoue K, Nishiyama N, Nagano K, Izumi N, Tsukioka T, Hanada S, Suehiro S. Factors predicting early postoperative liver cirrhosis-related complications after lung cancer surgery in patients with liver cirrhosis. Interactive Cardiovascular and Thoracic Surgery. 6: 720-30. PMID 17766277 DOI: 10.1510/ICVTS.2007.162487  0.092
1992 Yokota T, Takahashi M, Ishihara T, Yamashita Y, Gondo T, Kawamura S, Hoshii Y, Koga M, Iwata T, Uchino F. Amyloid enhancing factor (AEF). Isolation and biochemical and pathological characteristics. Acta Pathologica Japonica. 41: 798-805. PMID 1785340 DOI: 10.1111/j.1440-1827.1991.tb01621.x  0.092
2009 Iwata T, Nishiyama N, Nagano K, Izumi N, Tsukioka T, Hanada S, Kimura T, Kudoh S, Hirata K, Suehiro S. Squamous cell carcinoma presenting as a solitary growing cyst in lung: a diagnostic pitfall in daily clinical practice. Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia. 15: 174-7. PMID 19597393  0.092
2005 Iwata T, Mitani A, Ishihara Y, Tanaka S, Yamamoto G, Kikuchi T, Naganawa T, Matsumura Y, Suga T, Koide M, Sobue T, Suzuki T, Noguchi T. Actinobacillus actinomycetemcomitans Y4 capsular polysaccharide induces IL-1beta mRNA expression through the JNK pathway in differentiated THP-1 cells. Clinical and Experimental Immunology. 141: 261-9. PMID 15996190 DOI: 10.1111/j.1365-2249.2005.02836.x  0.092
2020 Hayashi T, Kameya S, Mizobuchi K, Kubota D, Kikuchi S, Yoshitake K, Mizota A, Murakami A, Iwata T, Nakano T. Genetic defects of CHM and visual acuity outcome in 24 choroideremia patients from 16 Japanese families. Scientific Reports. 10: 15883. PMID 32985515 DOI: 10.1038/s41598-020-72623-1  0.092
2008 Kawakami Y, Fujita T, Kudo C, Sakurai T, Udagawa M, Yaguchi T, Hasegawa G, Hayashi E, Ueda Y, Iwata T, Wang Q, Okada S, Tsukamoto N, Matsuzaki Y, Sumimoto H. Dendritic cell based personalized immunotherapy based on cancer antigen research. Frontiers in Bioscience : a Journal and Virtual Library. 13: 1952-8. PMID 17981682 DOI: 10.2741/2814  0.092
2019 Iwata T, Ando K, Komatsu S. [Usefulness of CT Colonography for a Patient with Three Synchronous Primary Descending Colon Cancers]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 46: 957-959. PMID 31189825  0.092
2013 Okamoto T, Iwata T, Mizobuchi T, Hoshino H, Moriya Y, Yoshida S, Yoshino I. Surgical treatment for non-small cell lung cancer with ipsilateral pulmonary metastases. Surgery Today. 43: 1123-8. PMID 23224143 DOI: 10.1007/s00595-012-0452-x  0.092
2001 Yoshimura C, Miyamasu M, Nagase H, Iikura M, Yamaguchi M, Kawanami O, Morita Y, Iwata T, Yamamoto K, Hirai K. Glucocorticoids induce basophil apoptosis. The Journal of Allergy and Clinical Immunology. 108: 215-20. PMID 11496237 DOI: 10.1067/mai.2001.116575  0.091
2011 Sakairi Y, Hoshino H, Nakajima T, Fujiwara T, Ishibashi F, Tamura H, Wada H, Iwata T, Okamoto T, Mizobuchi T, Moriya Y, Yoshida S, Yasufuku K, Yoshino I. Clinical outcome of cN0 non-small cell lung cancer patients staged by thin-slice CT, FDG-PET, and EBUS-TBNA. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 7052. PMID 28020033 DOI: 10.1200/jco.2011.29.15_suppl.7052  0.091
2017 Iwata T, Niimura Y, Kobayashi C, Shirakawa D, Suzuki H, Enomoto T, Touhara K, Yoshihara Y, Hirota J. A long-range cis-regulatory element for class I odorant receptor genes. Nature Communications. 8: 885. PMID 29026079 DOI: 10.1038/S41467-017-00870-4  0.091
1992 Heim R, Iwata T, Zvaritch E, Adamo HP, Rutishauser B, Strehler EE, Guerini D, Carafoli E. Expression, purification, and properties of the plasma membrane Ca2+ pump and of its N-terminally truncated 105-kDa fragment. The Journal of Biological Chemistry. 267: 24476-84. PMID 1332959  0.091
2007 Nakada T, Ishizuka Y, Iwata T, Toyoda F, Kato T, Conlon JM, Kikuyama S. Evidence for processing enzymes in the abdominal gland of the newt, Cynops pyrrhogaster, that generate sodefrin from its biosynthetic precursor. Zoological Science. 24: 521-4. PMID 17867852 DOI: 10.2108/zsj.24.521  0.091
2006 Iwata T, Inoue K, Mizuguchi S, Morita R, Tsukioka T, Suehiro S. Thymic small cell carcinoma associated with pulmonary squamous cell carcinoma. The Annals of Thoracic Surgery. 82: 2266-8. PMID 17126147 DOI: 10.1016/J.ATHORACSUR.2006.05.007  0.091
2022 Yoshida S, Hatasa M, Ohsugi Y, Tsuchiya Y, Liu A, Niimi H, Morita K, Shimohira T, Sasaki N, Maekawa S, Shiba T, Hirota T, Okano T, Hirose A, Ibi R, ... ... Iwata T, et al. Administration Induces Gestational Obesity, Alters Gene Expression in the Liver and Brown Adipose Tissue in Pregnant Mice, and Causes Underweight in Fetuses. Frontiers in Cellular and Infection Microbiology. 11: 745117. PMID 35096633 DOI: 10.3389/fcimb.2021.745117  0.091
2023 Ito M, Abe S, Adachi S, Oshima Y, Takeuchi A, Ohashi W, Iwata T, Ogawa T, Ota A, Kubota Y, Okuda T, Suzuki K. Solid tumours showing oligoprogression to immune checkpoint inhibitors have the potential for abscopal effects. Japanese Journal of Radiology. PMID 38093137 DOI: 10.1007/s11604-023-01516-w  0.091
2012 Nishioka M, Shimada M, Kurita N, Iwata T, Morimoto S, Yoshikawa K, Higashijima J, Miyatani T. Clinicopathological analysis of distal margin for rectal cancer after preoperative chemoradiation therapy. Hepato-Gastroenterology. 59: 2142-6. PMID 22366527 DOI: 10.5754/hge11840  0.09
2019 Iwata T, Ando K, Mishima H. [A Case of an Elderly Patient with Multiple Lung Metastases of Postoperative Pancreatic Cancer in Whom Lung Metastases Were Controlled by Biweekly Dose-Down Administration of Gemcitabine]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 46: 1453-1455. PMID 31530789  0.09
2021 Masuda H, Arisaka Y, Hakariya M, Iwata T, Yoda T, Yui N. Synergy of molecularly mobile polyrotaxane surfaces with endothelial cell co-culture for mesenchymal stem cell mineralization. Rsc Advances. 11: 18685-18692. PMID 35480955 DOI: 10.1039/d1ra01296g  0.09
2013 Inoue Y, Iwata T, Okugawa Y, Kawamoto A, Hiro J, Toiyama Y, Tanaka K, Uchida K, Mohri Y, Miki C, Kusunoki M. Prognostic significance of a systemic inflammatory response in patients undergoing multimodality therapy for advanced colorectal cancer. Oncology. 84: 100-7. PMID 23147449 DOI: 10.1159/000343822  0.09
2016 Suga A, Mizota A, Kato M, Kuniyoshi K, Yoshitake K, Sultan W, Yamazaki M, Shimomura Y, Ikeo K, Tsunoda K, Iwata T. Identification of Novel Mutations in the LRR-Cap Domain of C21orf2 in Japanese Patients With Retinitis Pigmentosa and Cone-Rod Dystrophy. Investigative Ophthalmology & Visual Science. 57: 4255-4263. PMID 27548899 DOI: 10.1167/iovs.16-19450  0.09
2016 Iwata T, Otsuka S, Tsubokura K, Kurbangalieva A, Arai D, Fukase K, Nakao Y, Tanaka K. One-pot Evolution of Ageladine A through a Bio-Inspired Cascade towards Selective Modulators of Neuronal Differentiation. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27557614 DOI: 10.1002/chem.201602651  0.09
2013 Iwata T, Tanaka K, Inoue Y, Toiyama Y, Hiro J, Fujikawa H, Okugawa Y, Uchida K, Mohri Y, Kusunoki M. Macrophage inflammatory protein-3 alpha (MIP-3a) is a novel serum prognostic marker in patients with colorectal cancer. Journal of Surgical Oncology. 107: 160-6. PMID 22926691 DOI: 10.1002/jso.23247  0.09
2020 Yang L, Fujinami K, Ueno S, Kuniyoshi K, Hayashi T, Kondo M, Mizota A, Naoi N, Shinoda K, Kameya S, Fujinami-Yokokawa Y, Liu X, Arno G, Pontikos N, Kominami T, ... ... Iwata T, et al. Genetic Spectrum of EYS-associated Retinal Disease in a Large Japanese Cohort: Identification of Disease-associated Variants with Relatively High Allele Frequency. Scientific Reports. 10: 5497. PMID 32218477 DOI: 10.1038/s41598-020-62119-3  0.09
2005 Iwata T, Nozaki D, Tokutomi S, Kandori H. Comparative investigation of the LOV1 and LOV2 domains in Adiantum phytochrome3. Biochemistry. 44: 7427-34. PMID 15895986 DOI: 10.1021/bi047281y  0.09
2009 Iwata T, Inoue K, Nishiyama N, Nagano K, Izumi N, Mizuguchi S, Morita R, Tsukioka T, Hanada S, Suehiro S. Lung cancer surgery in nonagenarians. Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia. 14: 314-8. PMID 18989248  0.09
2020 Ohsugi Y, Katagiri S, Hirota T, Niimi H, Hatasa M, Watanabe K, Shimohira T, Mizutani K, Kitazawa M, Matsuzawa A, Kadokura H, Yokose S, Iwata T, Aoki A. Laser irradiation decreases sclerostin expression in bone and osteogenic cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32757452 DOI: 10.1096/fj.202001032R  0.09
1990 Tomii K, Iwata T, Oida K, Kohri Y, Taguchi Y, Nanbu Y, Kubo Y, Yuba Y, Mino M. [Bronchiectasis with normal paranasal sinus roentgenogram]. Nihon Kyobu Shikkan Gakkai Zasshi. 28: 551-7. PMID 2214398  0.09
1999 Kato T, Inoue K, Nishiyama N, Nishida T, Iwata T, Fukuhara K, Kinoshita H, Sakurai M, Wakasa K. [Resected case of synchronous double cancer of lung and ovarium]. Kyobu Geka. the Japanese Journal of Thoracic Surgery. 52: 416-8. PMID 10319635  0.09
2017 Ueno S, Nakanishi A, Sayo A, Kominami T, Ito Y, Hayashi T, Tsunoda K, Iwata T, Terasaki H. Differences in ocular findings in two siblings: one with complete and other with incomplete achromatopsia. Documenta Ophthalmologica. Advances in Ophthalmology. PMID 28197754 DOI: 10.1007/s10633-017-9577-y  0.09
2006 Okada T, Akada M, Fujita T, Iwata T, Goto Y, Kido K, Okada T, Matsuzaki Y, Kobayashi K, Matsuno S, Sunamura M, Kawakami Y. A novel cancer testis antigen that is frequently expressed in pancreatic, lung, and endometrial cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 191-7. PMID 16397042 DOI: 10.1158/1078-0432.CCR-05-1206  0.089
2020 Kato D, Yaguchi T, Iwata T, Katoh Y, Morii K, Tsubota K, Takise Y, Tamiya M, Kamada H, Akiba H, Tsumoto K, Serada S, Naka T, Nishimura R, Nakagawa T, et al. GPC1 specific CAR-T cells eradicate established solid tumor without adverse effects and synergize with anti-PD-1 Ab. Elife. 9. PMID 32228854 DOI: 10.7554/eLife.49392  0.089
2013 Kanemitsu Y, Matsumoto H, Izuhara K, Tohda Y, Kita H, Horiguchi T, Kuwabara K, Tomii K, Otsuka K, Fujimura M, Ohkura N, Tomita K, Yokoyama A, Ohnishi H, Nakano Y, ... ... Iwata T, et al. Increased periostin associates with greater airflow limitation in patients receiving inhaled corticosteroids. The Journal of Allergy and Clinical Immunology. 132: 305-12.e3. PMID 23791506 DOI: 10.1016/j.jaci.2013.04.050  0.089
2003 Mukae S, Itoh S, Aoki S, Iwata T, Nishio K, Sato R, Katagiri T. Association of polymorphisms of the renin-angiotensin system and bradykinin B2 receptor with ACE-inhibitor-related cough. Journal of Human Hypertension. 16: 857-63. PMID 12522467 DOI: 10.1038/sj.jhh.1001486  0.089
2021 Sano A, Kakazu E, Hamada S, Inoue J, Ninomiya M, Iwata T, Tsuruoka M, Sato K, Masamune A. Steatotic hepatocytes release mature VLDL via methionine and tyrosine metabolism in a Keap1-Nrf2 dependent manner. Hepatology (Baltimore, Md.). PMID 33724516 DOI: 10.1002/hep.31808  0.089
2021 Kaibuchi N, Iwata T, Okamoto T, Kawase-Koga Y, Yamato M. Cell therapy for medication-related osteonecrosis of the jaw: update on treatment strategies. European Cells & Materials. 41: 31-39. PMID 33400815 DOI: 10.22203/eCM.v041a03  0.089
2020 Park JY, Park CH, Yi T, Kim SN, Iwata T, Yun JH. rhBMP-2 Pre-Treated Human Periodontal Ligament Stem Cell Sheets Regenerate a Mineralized Layer Mimicking Dental Cementum. International Journal of Molecular Sciences. 21. PMID 32466616 DOI: 10.3390/ijms21113767  0.089
2006 Izumi K, Kurosaka D, Iwata T, Oguchi Y, Tanaka Y, Mashima Y, Tsubota K. Involvement of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in corneal fibroblasts during corneal wound healing. Investigative Ophthalmology & Visual Science. 47: 591-8. PMID 16431955 DOI: 10.1167/iovs.05-0097  0.089
2023 Yamauchi Y, Nakajima J, Mun M, Shintani Y, Kuroda H, Iwata T, Endo M, Azuma Y, Chida M, Sakao Y, Yoshino I, Ikeda N, Matsuguma H, Funai K, Hashimoto H, et al. Survival after Lung Metastasectomy from Esophageal Cancer: Results from a Multi-Institutional Database. Cancers. 15. PMID 36900265 DOI: 10.3390/cancers15051472  0.089
2019 Kaibuchi N, Iwata T, Onizuka S, Yano K, Tsumanuma Y, Yamato M, Okano T, Ando T. Allogeneic multipotent mesenchymal stromal cell sheet transplantation promotes healthy healing of wounds caused by zoledronate and dexamethasone in canine mandibular bones. Regenerative Therapy. 10: 77-83. PMID 30671501 DOI: 10.1016/j.reth.2018.10.008  0.089
2008 Leontiou CA, Gueorguiev M, van der Spuy J, Quinton R, Lolli F, Hassan S, Chahal HS, Igreja SC, Jordan S, Rowe J, Stolbrink M, Christian HC, Wray J, Bishop-Bailey D, Berney DM, ... ... Iwata T, et al. The role of the aryl hydrocarbon receptor-interacting protein gene in familial and sporadic pituitary adenomas. The Journal of Clinical Endocrinology and Metabolism. 93: 2390-401. PMID 18381572 DOI: 10.1210/Jc.2007-2611  0.089
1999 Iwata T, Uchida S, Hori M, Sakai K, Towatari T, Kido H. Human parathyroid hormone (1-34) increases urinary excretion of lysosomal enzymes in rats. Life Sciences. 65: 1725-32. PMID 10576551 DOI: 10.1016/s0024-3205(99)00424-5  0.089
2013 Iwata T, Tanaka K, Tahara T, Nozaki S, Onoe H, Watanabe Y, Fukase K. A conformationally fixed analog of the peptide mimic Grb2-SH2 domain: synthesis and evaluation against the A431 cancer cell. Molecular Biosystems. 9: 1019-25. PMID 23403766 DOI: 10.1039/c3mb25462c  0.089
2009 Iwata T, Nishiyama N, Nagano K, Izumi N, Mizuguchi S, Morita R, Tsukioka T, Hanada S, Inoue K, Kubo S, Takemura S, Suehiro S. Pulmonary resection for non-small cell lung cancer in patients with hepatocellular carcinoma. World Journal of Surgery. 32: 2204-12. PMID 18668284 DOI: 10.1007/s00268-008-9691-9  0.088
2006 Minegishi Y, Saito M, Morio T, Watanabe K, Agematsu K, Tsuchiya S, Takada H, Hara T, Kawamura N, Ariga T, Kaneko H, Kondo N, Tsuge I, Yachie A, Sakiyama Y, ... Iwata T, et al. Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity. Immunity. 25: 745-55. PMID 17088085 DOI: 10.1016/j.immuni.2006.09.009  0.088
2005 Nakasako M, Iwata T, Inoue K, Tokutomi S. Light-induced global structural changes in phytochrome A regulating photomorphogenesis in plants. The Febs Journal. 272: 603-12. PMID 15654897 DOI: 10.1111/j.1742-4658.2004.04508.x  0.088
2022 Kaibuchi N, Iwata T, Koga YK, Okamoto T. Novel Cell Therapy Using Mesenchymal Stromal Cell Sheets for Medication-Related Osteonecrosis of the Jaw. Frontiers in Bioengineering and Biotechnology. 10: 902349. PMID 35646846 DOI: 10.3389/fbioe.2022.902349  0.088
2015 Iwata T, Fujii T, Morii K, Saito M, Sugiyama J, Nishio H, Morisada T, Tanaka K, Yaguchi T, Kawakami Y, Aoki D. Cytokine profile in cervical mucosa of Japanese patients with cervical intraepithelial neoplasia. International Journal of Clinical Oncology. 20: 126-33. PMID 24578180 DOI: 10.1007/s10147-014-0680-8  0.088
2007 Iwata T, Nishiyama N, Izumi N, Tsukioka T, Suehiro S. Metastatic monophasic synovial sarcoma of the pleura. Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia. 13: 258-61. PMID 17717503  0.088
2003 Kano H, Ito Y, Matsuoka K, Iwata T, Saito H, Kohsaka T, Abe J. Role of T cells and gamma interferon in Yersinia pseudotuberculosis-derived mitogen (YPM)-induced toxicity in mice. Advances in Experimental Medicine and Biology. 529: 137-9. PMID 12756745 DOI: 10.1007/0-306-48416-1_27  0.088
2018 Takeno A, Masuzawa T, Murakami K, Iwata T, Yamamoto A, Kawai K, Sakamoto T, Inadome J, Naito A, Katsura Y, Ohmura Y, Kagawa Y, Egawa C, Takeda Y, Murata K. [Tracheo-Bronchial Airway Stenting for Airway Stenosis Due to Inoperable Advanced Esophageal Cancers]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 45: 2241-2243. PMID 30692344  0.088
2011 Iwata T, Iida S, Hanada S, Inoue H, Morikawa Y, Inoue K, Kobayashi Y, Miura T. Transbronchial occlusion of a malignant bronchopleural fistula with cyanoacrylate glue. Journal of Bronchology & Interventional Pulmonology. 18: 176-8. PMID 23169091 DOI: 10.1097/LBR.0b013e3182180d9c  0.088
2007 Oyama T, Sugio K, Uramoto H, Iwata T, Onitsuka T, Isse T, Nozoe T, Kagawa N, Yasumoto K, Kawamoto T. Increased cytochrome P450 and aryl hydrocarbon receptor in bronchial epithelium of heavy smokers with non-small cell lung carcinoma carries a poor prognosis. Frontiers in Bioscience : a Journal and Virtual Library. 12: 4497-503. PMID 17485391 DOI: 10.2741/2404  0.088
2007 Matsuoka D, Iwata T, Zikihara K, Kandori H, Tokutomi S. Primary processes during the light-signal transduction of phototropin. Photochemistry and Photobiology. 83: 122-30. PMID 16802859 DOI: 10.1562/2006-03-29-RA-861  0.088
1998 Shinomiya M, Iwata T, Kasuya K, Doi Y. Cloning of the gene for poly(3-hydroxybutyric acid) depolymerase of Comamonas testosteroni and functional analysis of its substrate-binding domain. Fems Microbiology Letters. 154: 89-94. PMID 9297825 DOI: 10.1111/j.1574-6968.1997.tb12628.x  0.088
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