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Rafael Linden - Publications

Affiliations: 
Federal University Rio de Janeiro (UFRJ) 
Area:
Neurodegeneration
Website:
http://www.biof.ufrj.br/neurogen

135 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Adão-Novaes J, Valverde RHF, Landemberger MC, Silveira MS, Simões-Pires EN, Lowe J, Linden R. Substrain-related dependence of Cu(I)-ATPase activity among prion protein-null mice. Brain Research. 146550. PMID 31726043 DOI: 10.1016/j.brainres.2019.146550  1
2019 Lani R, Dias MS, Abreu CA, Araújo VG, Gonçalo T, Nascimento-Dos-Santos G, Dantas AM, Allodi S, Fiorani M, Petrs-Silva H, Linden R. A subacute model of glaucoma based on limbal plexus cautery in pigmented rats. Scientific Reports. 9: 16286. PMID 31705136 DOI: 10.1038/s41598-019-52500-2  1
2019 Dias MS, Araujo VG, Vasconcelos T, Li Q, Hauswirth WW, Linden R, Petrs-Silva H. Retina transduction by rAAV2 after intravitreal injection: comparison between mouse and rat. Gene Therapy. PMID 31562387 DOI: 10.1038/s41434-019-0100-9  1
2019 Rocha-Martins M, de Toledo BC, Santos-França PL, Oliveira-Valença VM, Vieira-Vieira CH, Matos-Rodrigues GE, Linden R, Norden C, Martins RAP, Silveira MS. genesis of retinal ganglion cells by targeted expression of . Development (Cambridge, England). 146. PMID 31405994 DOI: 10.1242/dev.176586  1
2018 Guimarães RPM, Landeira BS, Coelho DM, Golbert DCF, Silveira MS, Linden R, de Melo Reis RA, Costa MR. Evidence of Müller Glia Conversion Into Retina Ganglion Cells Using Neurogenin2. Frontiers in Cellular Neuroscience. 12: 410. PMID 30483060 DOI: 10.3389/fncel.2018.00410  1
2018 da Silva Chagas L, Trindade P, Gomes ALT, Mendonça HR, Campello-Costa P, da Cunha Faria Melibeu A, Linden R, Serfaty CA. Rapid plasticity of intact axons following a lesion to the visual pathways during early brain development is triggered by microglial activation. Experimental Neurology. PMID 30312606 DOI: 10.1016/j.expneurol.2018.10.002  1
2017 Cabral-Miranda F, Nicoloso-Simões E, Adão-Novaes J, Chiodo V, Hauswirth WW, Linden R, Chiarini LB, Petrs-Silva H. rAAV8-733-Mediated Gene Transfer of CHIP/Stub-1 Prevents Hippocampal Neuronal Death in Experimental Brain Ischemia. Molecular Therapy : the Journal of the American Society of Gene Therapy. 25: 392-400. PMID 28153090 DOI: 10.1016/j.ymthe.2016.11.017  1
2016 Beckman D, Linden R. A roadmap for investigating the role of the prion protein in depression associated with neurodegenerative disease. Prion. 0. PMID 27057694 DOI: 10.1080/19336896.2016.1152437  1
2016 Carneiro MV, Americo TA, Guimarães MZ, Linden R. The prion protein selectively binds to and modulates the content of purinergic receptor P2X4R. Biochemical and Biophysical Research Communications. PMID 26946358 DOI: 10.1016/j.bbrc.2016.02.122  1
2016 Hollmann G, Linden R, Giangrande A, Allodi S. Increased p53 and decreased p21 accompany apoptosis induced by ultraviolet radiation in the nervous system of a crustacean. Aquatic Toxicology (Amsterdam, Netherlands). 173: 1-8. PMID 26807499 DOI: 10.1016/j.aquatox.2015.12.025  1
2015 Beckman D, Santos LE, Americo TA, Ledo JH, de Mello FG, Linden R. Reply to Altered Monoaminergic Systems and Depressive-like Behavior in Congenic Prion Protein Knock-out Mice. The Journal of Biological Chemistry. 290: 26351. PMID 26500296 DOI: 10.1074/jbc.L115.689232  1
2015 Pinheiro LP, Linden R, Mariante RM. Activation and function of murine primary microglia in the absence of the prion protein. Journal of Neuroimmunology. 286: 25-32. PMID 26298321 DOI: 10.1016/j.jneuroim.2015.07.002  1
2015 Beckman D, Santos LE, Americo TA, Ledo JH, de Mello FG, Linden R. Prion Protein Modulates Monoaminergic Systems and Depressive-like Behavior in Mice. The Journal of Biological Chemistry. 290: 20488-98. PMID 26152722 DOI: 10.1074/jbc.M115.666156  1
2015 Hollmann G, Ferreira Gde J, Geihs MA, Vargas MA, Nery LE, Leitão Á, Linden R, Allodi S. Antioxidant activity stimulated by ultraviolet radiation in the nervous system of a crustacean. Aquatic Toxicology (Amsterdam, Netherlands). 160: 151-62. PMID 25630046 DOI: 10.1016/j.aquatox.2015.01.008  1
2015 Beckman D, Santos LE, Americo TA, Ledo JH, De Mello FG, Linden R. Prion protein modulates monoaminergic systems and depressive-like behavior in mice Journal of Biological Chemistry. 290: 20488-20498. DOI: 10.1074/jbc.M115.666156  1
2014 Cabral Miranda F, Adão-Novaes J, Hauswirth WW, Linden R, Petrs-Silva H, Chiarini LB. CHIP, a carboxy terminus HSP-70 interacting protein, prevents cell death induced by endoplasmic reticulum stress in the central nervous system. Frontiers in Cellular Neuroscience. 8: 438. PMID 25620910 DOI: 10.3389/fncel.2014.00438  0.6
2014 Linden R, Matte U. A snapshot of gene therapy in Latin America. Genetics and Molecular Biology. 37: 294-8. PMID 24764763 DOI: 10.1590/S1415-47572014000200015  1
2014 Njaine B, Rocha-Martins M, Vieira-Vieira CH, De-Melo LD, Linden R, Braas K, May V, Martins RA, Silveira MS. Pleiotropic functions of pituitary adenylyl cyclase-activating polypeptide on retinal ontogenesis: involvement of KLF4 in the control of progenitor cell proliferation. Journal of Molecular Neuroscience : Mn. 54: 430-42. PMID 24715357 DOI: 10.1007/s12031-014-0299-2  1
2014 Petrs-Silva H, Linden R. Advances in gene therapy technologies to treat retinitis pigmentosa. Clinical Ophthalmology (Auckland, N.Z.). 8: 127-36. PMID 24391438 DOI: 10.2147/OPTH.S38041  1
2013 Petrs-Silva H, Linden R. Advances in recombinant adeno-associated viral vectors for gene delivery. Current Gene Therapy. 13: 335-45. PMID 24060313 DOI: 10.2174/15665232113136660028  1
2013 Luz AJ, Poeta J, Linden R, Antunes MV, Caminha LI, Sprinz E. Related factors to atazanavir plasma levels in a cohort of HIV positive individuals with undetectable viral load. The Brazilian Journal of Infectious Diseases : An Official Publication of the Brazilian Society of Infectious Diseases. 17: 657-60. PMID 23933406 DOI: 10.1016/j.bjid.2013.04.002  0.01
2013 Antunes MV, Niederauer CG, Linden R. Development, validation and clinical evaluation of a dried urine spot method for determination of hippuric acid and creatinine. Clinical Biochemistry. 46: 1276-80. PMID 23868019 DOI: 10.1016/j.clinbiochem.2013.07.004  0.01
2013 Hajj GN, Arantes CP, Dias MV, Roffé M, Costa-Silva B, Lopes MH, Porto-Carreiro I, Rabachini T, Lima FR, Beraldo FH, Prado MA, Prado MM, Linden R, Martins VR. The unconventional secretion of stress-inducible protein 1 by a heterogeneous population of extracellular vesicles. Cellular and Molecular Life Sciences : Cmls. 70: 3211-27. PMID 23543276 DOI: 10.1007/s00018-013-1328-y  1
2012 Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Linden R, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490  0.4
2012 Mariante RM, Nóbrega A, Martins RA, Areal RB, Bellio M, Linden R. Neuroimmunoendocrine regulation of the prion protein in neutrophils. The Journal of Biological Chemistry. 287: 35506-15. PMID 22910907 DOI: 10.1074/jbc.M112.394924  1
2012 Ribas VT, Gonçalves BS, Linden R, Chiarini LB. Activation of c-Jun N-terminal kinase (JNK) during mitosis in retinal progenitor cells. Plos One. 7: e34483. PMID 22496813 DOI: 10.1371/journal.pone.0034483  1
2012 Linden R, Cordeiro Y, Lima LM. Allosteric function and dysfunction of the prion protein. Cellular and Molecular Life Sciences : Cmls. 69: 1105-24. PMID 21984610 DOI: 10.1007/s00018-011-0847-7  1
2011 Lindoso RS, Araujo DS, Adão-Novaes J, Mariante RM, Verdoorn KS, Fragel-Madeira L, Caruso-Neves C, Linden R, Vieyra A, Einicker-Lamas M. Paracrine interaction between bone marrow-derived stem cells and renal epithelial cells. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 28: 267-78. PMID 21865734 DOI: 10.1159/000331739  1
2011 Ribas VT, Arruda-Carvalho M, Linden R, Chiarini LB. Early c-Jun N-terminal kinase-dependent phosphorylation of activating transcription factor-2 is associated with degeneration of retinal ganglion cells. Neuroscience. 180: 64-74. PMID 21300140 DOI: 10.1016/j.neuroscience.2011.01.059  1
2011 Fragel-Madeira L, Meletti T, Mariante RM, Monteiro RQ, Einicker-Lamas M, Bernardo RR, Lopes AH, Linden R. Platelet activating factor blocks interkinetic nuclear migration in retinal progenitors through an arrest of the cell cycle at the S/G2 transition. Plos One. 6: e16058. PMID 21298035 DOI: 10.1371/journal.pone.0016058  1
2011 Marra C, Gomes Moret D, de Souza Corrêa A, Chagas da Silva F, Moraes P, Linden R, Sholl-Franco A. Protein kinases JAK and ERK mediate protective effect of interleukin-2 upon ganglion cells of the developing rat retina. Journal of Neuroimmunology. 233: 120-6. PMID 21262542 DOI: 10.1016/j.jneuroim.2010.12.008  1
2011 Trindade P, Antonioli-Santos R, Teixeira AC, Lanzillotta-Mattos B, Melibeu AC, Campello-Costa P, Linden R, Serfaty CA. Evidence for a role of calcineurin in the development of retinocollicular fine topography. Neuroscience Letters. 487: 47-52. PMID 20920550 DOI: 10.1016/j.neulet.2010.09.071  1
2011 Beraldo FH, Arantes CP, Santos TG, Machado CF, Roffe M, Hajj GN, Lee KS, Magalhães AC, Caetano FA, Mancini GL, Lopes MH, Américo TA, Magdesian MH, Ferguson SS, Linden R, et al. Metabotropic glutamate receptors transduce signals for neurite outgrowth after binding of the prion protein to laminin γ1 chain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 265-79. PMID 20876210 DOI: 10.1096/fj.10-161653  1
2010 Sternberg C, Benchimol M, Linden R. Caspase dependence of the death of neonatal retinal ganglion cells induced by axon damage and induction of autophagy as a survival mechanism. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 43: 950-6. PMID 20802972 DOI: 10.1590/S0100-879X2010007500082  1
2010 Njaine B, Martins RA, Santiago MF, Linden R, Silveira MS. Pituitary adenylyl cyclase-activating polypeptide controls the proliferation of retinal progenitor cells through downregulation of cyclin D1. The European Journal of Neuroscience. 32: 311-21. PMID 20646049 DOI: 10.1111/j.1460-9568.2010.07286.x  1
2010 Adão-Novaes J, de Cássia Belem Guterrres C, Linden R, Sholl-Franco A. Rod photoreceptor cell death is induced by okadaic acid through activation of PKC and L-type voltage-dependent Ca2+ channels and prevented by IGF-1. Neurochemistry International. 57: 128-35. PMID 20466029 DOI: 10.1016/j.neuint.2010.04.021  1
2010 Sholl-Franco A, Fragel-Madeira L, Macama Ada C, Linden R, Ventura AL. ATP controls cell cycle and induces proliferation in the mouse developing retina. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 28: 63-73. PMID 19799993 DOI: 10.1016/j.ijdevneu.2009.09.004  1
2010 Martins VR, Beraldo FH, Hajj GN, Lopes MH, Lee KS, Prado MA, Linden R. Prion protein: orchestrating neurotrophic activities. Current Issues in Molecular Biology. 12: 63-86. PMID 19767651  1
2010 Linden R. Terapia gênica: O que é, o que não é e o que será Estudos Avancados. 24: 31-69. DOI: 10.1590/S0103-40142010000300004  1
2010 Linden R, Martins RAP, Silveira MS, Borges HL, Sholl-Franco A, Fragel-Madeira L, Dudenhoeffer-Carneiro AC. Tissue biology of proliferation and cell death among retinal progenitor cells Perspectives of Stem Cells: From Tools For Studying Mechanisms of Neuronal Differentiation Towards Therapy. 191-230. DOI: 10.1007/978-90-481-3375-8_13  1
2009 Romano SA, Cordeiro Y, Lima LM, Lopes MH, Silva JL, Foguel D, Linden R. Reciprocal remodeling upon binding of the prion protein to its signaling partner hop/STI1. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 4308-16. PMID 19703931 DOI: 10.1096/fj.09-138974  1
2009 Martini SV, Fagundes SS, Schmidt AC, Avila M, Ornellas DS, Ribas VT, Petrs-Silva H, Linden R, Faffe DS, Guggino SE, Rocco PR, Zin WA, Morales MM. Does the use of recombinant AAV5 in pulmonary gene therapy lead to lung damage? Respiratory Physiology & Neurobiology. 168: 203-9. PMID 19573627 DOI: 10.1016/j.resp.2009.06.016  1
2009 Adão-Novaes J, Guterres Cde C, da Silva AG, Campello-Costa P, Linden R, Sholl-Franco A. Interleukin-4 blocks thapsigargin-induced cell death in rat rod photoreceptors: involvement of cAMP/PKA pathway. Journal of Neuroscience Research. 87: 2167-74. PMID 19235892 DOI: 10.1002/jnr.22026  1
2008 da Fonseca CO, Linden R, Futuro D, Gattass CR, Quirico-Santos T. Ras pathway activation in gliomas: a strategic target for intranasal administration of perillyl alcohol. Archivum Immunologiae Et Therapiae Experimentalis. 56: 267-76. PMID 18726148 DOI: 10.1007/s00005-008-0027-0  1
2008 Petrs-Silva H, Chiarini LB, Linden R. Nuclear proteasomal degradation and cytoplasmic retention underlie early nuclear exclusion of transcription factor Max upon axon damage. Experimental Neurology. 213: 202-9. PMID 18601921 DOI: 10.1016/j.expneurol.2008.06.001  1
2008 Caetano FA, Lopes MH, Hajj GN, Machado CF, Pinto Arantes C, Magalhães AC, Vieira Mde P, Américo TA, Massensini AR, Priola SA, Vorberg I, Gomez MV, Linden R, Prado VF, Martins VR, et al. Endocytosis of prion protein is required for ERK1/2 signaling induced by stress-inducible protein 1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6691-702. PMID 18579743 DOI: 10.1523/JNEUROSCI.1701-08.2008  1
2008 Linden R, Martins VR, Prado MA, Cammarota M, Izquierdo I, Brentani RR. Physiology of the prion protein. Physiological Reviews. 88: 673-728. PMID 18391177 DOI: 10.1152/physrev.00007.2007  1
2008 da Silva AG, Campello-Costa P, Linden R, Sholl-Franco A. Interleukin-4 blocks proliferation of retinal progenitor cells and increases rod photoreceptor differentiation through distinct signaling pathways. Journal of Neuroimmunology. 196: 82-93. PMID 18378323 DOI: 10.1016/j.jneuroim.2008.03.003  1
2008 Carneiro AC, Fragel-Madeira L, Silva-Neto MA, Linden R. A role for CK2 upon interkinetic nuclear migration in the cell cycle of retinal progenitor cells. Developmental Neurobiology. 68: 620-31. PMID 18278803 DOI: 10.1002/dneu.20613  1
2008 Borges HL, Linden R, Wang JY. DNA damage-induced cell death: lessons from the central nervous system. Cell Research. 18: 17-26. PMID 18087290 DOI: 10.1038/cr.2007.110  1
2008 Lassance RM, Pássaro CP, Martini SV, Castiglione RC, Gutierrez TM, Abreu SC, Antunes MA, Xisto DG, Cebotaru L, Petrs-Silva H, Zin WA, Guggino WB, Linden R, Rocco PR, Morales MM. Does the use of recombinant AAV2 in pulmonary gene therapy damage lung function? Respiratory Physiology & Neurobiology. 160: 91-8. PMID 17950048 DOI: 10.1016/j.resp.2007.09.002  1
2007 De Almeida Dias F, Souza Dos Santos AL, Ferreira-Pereira A, Romeiro A, Teixeira Zimmermann L, Cunha do Nascimento MT, Correa Atella G, Saraiva EM, Linden R, Hampshire Lopes A. Development of a ligand blot assay using biotinylated live cells. Journal of Biomolecular Screening. 12: 1006-10. PMID 17942794 DOI: 10.1177/1087057107307146  1
2007 Erlich RB, Kahn SA, Lima FR, Muras AG, Martins RA, Linden R, Chiarini LB, Martins VR, Moura Neto V. STI1 promotes glioma proliferation through MAPK and PI3K pathways. Glia. 55: 1690-8. PMID 17886292 DOI: 10.1002/glia.20579  1
2007 Arruda-Carvalho M, Njaine B, Silveira MS, Linden R, Chiarini LB. Hop/STI1 modulates retinal proliferation and cell death independent of PrPC. Biochemical and Biophysical Research Communications. 361: 474-80. PMID 17651690 DOI: 10.1016/j.bbrc.2007.07.038  1
2007 Americo TA, Chiarini LB, Linden R. Signaling induced by hop/STI-1 depends on endocytosis. Biochemical and Biophysical Research Communications. 358: 620-5. PMID 17498662 DOI: 10.1016/j.bbrc.2007.04.202  1
2007 Lobo DS, Pereira IB, Fragel-Madeira L, Medeiros LN, Cabral LM, Faria J, Bellio M, Campos RC, Linden R, Kurtenbach E. Antifungal Pisum sativum defensin 1 interacts with Neurospora crassa cyclin F related to the cell cycle. Biochemistry. 46: 987-96. PMID 17240982 DOI: 10.1021/bi061441j  1
2007 Magdesian MH, Tonelli RR, Fessel MR, Silveira MS, Schumacher RI, Linden R, Colli W, Alves MJ. A conserved domain of the gp85/trans-sialidase family activates host cell extracellular signal-regulated kinase and facilitates Trypanosoma cruzi infection. Experimental Cell Research. 313: 210-8. PMID 17101128 DOI: 10.1016/j.yexcr.2006.10.008  1
2006 Villegas SN, Njaine B, Linden R, Carri NG. Glial-derived neurotrophic factor (GDNF) prevents ethanol (EtOH) induced B92 glial cell death by both PI3K/AKT and MEK/ERK signaling pathways. Brain Research Bulletin. 71: 116-26. PMID 17113937 DOI: 10.1016/j.brainresbull.2006.08.014  1
2006 Silveira MS, Linden R. Neuroprotection by cAMP: Another brick in the wall. Advances in Experimental Medicine and Biology. 557: 164-76. PMID 16955710 DOI: 10.1007/0-387-30128-3_10  1
2006 Martins RA, Linden R, Dyer MA. Glutamate regulates retinal progenitors cells proliferation during development. The European Journal of Neuroscience. 24: 969-80. PMID 16925590 DOI: 10.1111/j.1460-9568.2006.04966.x  1
2006 Campos CB, Bédard PA, Linden R. Requirement of p38 stress-activated MAP kinase for cell death in the developing retina depends on the stage of cell differentiation. Neurochemistry International. 49: 494-9. PMID 16782232 DOI: 10.1016/j.neuint.2006.03.011  1
2006 Silva KL, Vasconcellos DV, Castro ED, Coelho AM, Linden R, Maia RC. Apoptotic effect of fludarabine is independent of expression of IAPs in B-cell chronic lymphocytic leukemia. Apoptosis : An International Journal On Programmed Cell Death. 11: 277-85. PMID 16502265 DOI: 10.1007/s10495-006-3560-5  1
2006 Linden R, Reese BE. Programmed cell death Retinal Development. 208-241. DOI: 10.1017/CBO9780511541629.013  1
2005 Lopes MH, Hajj GN, Muras AG, Mancini GL, Castro RM, Ribeiro KC, Brentani RR, Linden R, Martins VR. Interaction of cellular prion and stress-inducible protein 1 promotes neuritogenesis and neuroprotection by distinct signaling pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11330-9. PMID 16339028 DOI: 10.1523/JNEUROSCI.2313-05.2005  1
2005 Wasilewska-Sampaio AP, Silveira MS, Holub O, Goecking R, Gomes FC, Neto VM, Linden R, Ferreira ST, De Felice FG. Neuritogenesis and neuronal differentiation promoted by 2,4-dinitrophenol, a novel anti-amyloidogenic compound. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1627-36. PMID 16195371 DOI: 10.1096/fj.05-3812com  1
2005 Martins RA, Silveira MS, Curado MR, Police AI, Linden R. NMDA receptor activation modulates programmed cell death during early post-natal retinal development: a BDNF-dependent mechanism. Journal of Neurochemistry. 95: 244-53. PMID 16181428 DOI: 10.1111/j.1471-4159.2005.03360.x  1
2005 Serfaty CA, Campello-Costa P, Linden R. Rapid and long-term plasticity in the neonatal and adult retinotectal pathways following a retinal lesion. Brain Research Bulletin. 66: 128-34. PMID 15982529 DOI: 10.1016/j.brainresbull.2005.04.005  1
2005 de Almeida CJ, Linden R. Phagocytosis of apoptotic cells: a matter of balance. Cellular and Molecular Life Sciences : Cmls. 62: 1532-46. PMID 15905967 DOI: 10.1007/s00018-005-4511-y  1
2005 Linden R, Martins RA, Silveira MS. Control of programmed cell death by neurotransmitters and neuropeptides in the developing mammalian retina. Progress in Retinal and Eye Research. 24: 457-91. PMID 15845345 DOI: 10.1016/j.preteyeres.2004.10.001  1
2005 Petrs-Silva H, Chiodo V, Chiarini LB, Hauswirth WW, Linden R. Modulation of the expression of the transcription factor Max in rat retinal ganglion cells by a recombinant adeno-associated viral vector. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 38: 375-9. PMID 15761617  1
2005 Linden R. The surfer wears a suit. A report on the II Symposium on Creativity, Imagination and Interactivity in Science Education. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 38: 315-9. PMID 15761610  1
2005 de Almeida CJ, Chiarini LB, da Silva JP, E Silva PM, Martins MA, Linden R. The cellular prion protein modulates phagocytosis and inflammatory response. Journal of Leukocyte Biology. 77: 238-46. PMID 15539455 DOI: 10.1189/jlb.1103531  1
2004 Assunção Guimarães C, Linden R. Programmed cell deaths. Apoptosis and alternative deathstyles. European Journal of Biochemistry / Febs. 271: 1638-50. PMID 15096203 DOI: 10.1111/j.1432-1033.2004.04084.x  1
2004 Pinto DO, Ferreira PL, Andrade LR, Petrs-Silva H, Linden R, Abdelhay E, Araújo HM, Alonso CE, Pavão MS. Biosynthesis and metabolism of sulfated glycosaminoglycans during Drosophila melanogaster development. Glycobiology. 14: 529-36. PMID 15044397 DOI: 10.1093/glycob/cwh070  1
2004 Prado MA, Alves-Silva J, Magalhães AC, Prado VF, Linden R, Martins VR, Brentani RR. PrPc on the road: trafficking of the cellular prion protein. Journal of Neurochemistry. 88: 769-81. PMID 14756798  1
2004 Borges HL, Chao C, Xu Y, Linden R, Wang JY. Radiation-induced apoptosis in developing mouse retina exhibits dose-dependent requirement for ATM phosphorylation of p53. Cell Death and Differentiation. 11: 494-502. PMID 14752509 DOI: 10.1038/sj.cdd.4401366  1
2004 Petrs-Silva H, de Freitas FG, Linden R, Chiarini LB. Early nuclear exclusion of the transcription factor max is associated with retinal ganglion cell death independent of caspase activity. Journal of Cellular Physiology. 198: 179-87. PMID 14603520 DOI: 10.1002/jcp.10404  1
2003 Cabral-da-Silva MC, dos Santos NE, de Mello FG, Taylor JS, Tolkovsky AM, Linden R, Reis RA. Herbimycin A induces sympathetic neuron survival and protects against hypoxia. Neuroreport. 14: 2397-401. PMID 14663199 DOI: 10.1097/01.wnr.0000099603.19426.c8  1
2003 Chiarini LB, Leal-Ferreira ML, de Freitas FG, Linden R. Changing sensitivity to cell death during development of retinal photoreceptors. Journal of Neuroscience Research. 74: 875-83. PMID 14648592 DOI: 10.1002/jnr.10739  1
2003 Lee KS, Linden R, Prado MA, Brentani RR, Martins VR. Towards cellular receptors for prions. Reviews in Medical Virology. 13: 399-408. PMID 14625887 DOI: 10.1002/rmv.408  1
2003 Guimarães CA, Benchimol M, Amarante-Mendes GP, Linden R. Alternative programs of cell death in developing retinal tissue. The Journal of Biological Chemistry. 278: 41938-46. PMID 12917395 DOI: 10.1074/jbc.M306547200  1
2003 Cusato K, Bosco A, Rozental R, Guimarães CA, Reese BE, Linden R, Spray DC. Gap junctions mediate bystander cell death in developing retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 6413-22. PMID 12878681  1
2003 Erlich RB, Werneck CC, Mourão PA, Linden R. Major glycosaminoglycan species in the developing retina: synthesis, tissue distribution and effects upon cell death. Experimental Eye Research. 77: 157-65. PMID 12873445 DOI: 10.1016/S0014-4835(03)00129-5  1
2003 Mariante RM, Guimarães CA, Linden R, Benchimol M. Hydrogen peroxide induces caspase activation and programmed cell death in the amitochondrial Tritrichomonas foetus. Histochemistry and Cell Biology. 120: 129-41. PMID 12844218 DOI: 10.1007/s00418-003-0548-x  1
2003 Campos CB, Bédard PA, Linden R. Selective involvement of the PI3K/PKB/bad pathway in retinal cell death. Journal of Neurobiology. 56: 171-7. PMID 12838582 DOI: 10.1002/neu.10234  1
2002 Chiarini LB, de Freitas FG, Leal-Ferreira ML, Tolkovsky A, Linden R. Cytoplasmic c-Jun N-terminal immunoreactivity: a hallmark of retinal apoptosis. Cellular and Molecular Neurobiology. 22: 711-26. PMID 12585690 DOI: 10.1023/A:1021857007976  1
2002 Cusato K, Bosco A, Linden R, Reese BE. Cell death in the inner nuclear layer of the retina is modulated by BDNF. Brain Research. Developmental Brain Research. 139: 325-30. PMID 12480149 DOI: 10.1016/S0165-3806(02)00570-9  1
2002 Freire E, Gomes FC, Linden R, Neto VM, Coelho-Sampaio T. Structure of laminin substrate modulates cellular signaling for neuritogenesis. Journal of Cell Science. 115: 4867-76. PMID 12432074 DOI: 10.1242/jcs.00173  1
2002 Rehen SK, Cid M, Fragel-Madeira L, Linden R. Differential effects of cyclin-dependent kinase blockers upon cell death in the developing retina. Brain Research. 947: 78-83. PMID 12144855 DOI: 10.1016/S0006-8993(02)02909-8  1
2002 Chiarini LB, Freitas AR, Zanata SM, Brentani RR, Martins VR, Linden R. Cellular prion protein transduces neuroprotective signals. The Embo Journal. 21: 3317-26. PMID 12093733 DOI: 10.1093/emboj/cdf324  1
2002 Zanata SM, Lopes MH, Mercadante AF, Hajj GN, Chiarini LB, Nomizo R, Freitas AR, Cabral AL, Lee KS, Juliano MA, de Oliveira E, Jachieri SG, Burlingame A, Huang L, Linden R, et al. Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection. The Embo Journal. 21: 3307-16. PMID 12093732 DOI: 10.1093/emboj/cdf325  1
2002 Borges VM, Lopes MF, Falcão H, Leite-Júnior JH, Rocco PR, Davidson WF, Linden R, Zin WA, DosReis GA. Apoptosis underlies immunopathogenic mechanisms in acute silicosis. American Journal of Respiratory Cell and Molecular Biology. 27: 78-84. PMID 12091249 DOI: 10.1165/ajrcmb.27.1.4717  1
2002 Campos CB, Bédard PA, Linden R. Activation of p38 mitogen-activated protein kinase during normal mitosis in the developing retina. Neuroscience. 112: 583-91. PMID 12074900 DOI: 10.1016/S0306-4522(02)00096-9  1
2002 Martins VR, Linden R, Prado MA, Walz R, Sakamoto AC, Izquierdo I, Brentani RR. Cellular prion protein: on the road for functions. Febs Letters. 512: 25-8. PMID 11852045 DOI: 10.1016/S0014-5793(02)02291-3  1
2002 Silveira MS, Costa MR, Bozza M, Linden R. Pituitary adenylyl cyclase-activating polypeptide prevents induced cell death in retinal tissue through activation of cyclic AMP-dependent protein kinase. The Journal of Biological Chemistry. 277: 16075-80. PMID 11847214 DOI: 10.1074/jbc.M110106200  1
2002 Reis RA, Cabral da Silva MC, Loureiro dos Santos NE, Bampton E, Taylor JS, de Mello FG, Linden R. Sympathetic neuronal survival induced by retinal trophic factors. Journal of Neurobiology. 50: 13-23. PMID 11748629 DOI: 10.1002/neu.10008  1
2001 Borges VM, Falcão H, Leite-Júnior JH, Alvim L, Teixeira GP, Russo M, Nóbrega AF, Lopes MF, Rocco PM, Davidson WF, Linden R, Yagita H, Zin WA, DosReis GA. Fas ligand triggers pulmonary silicosis. The Journal of Experimental Medicine. 194: 155-64. PMID 11457890 DOI: 10.1084/jem.194.2.155  1
2001 Neves DD, Rehen SK, Linden R. Differentiation-dependent sensitivity to cell death induced in the developing retina by inhibitors of the ubiquitin-proteasome proteolytic pathway. The European Journal of Neuroscience. 13: 1938-44. PMID 11403687 DOI: 10.1046/j.0953-816X.2001.01571.x  1
2001 Schmidt SL, Vitral RW, Linden R. Depletion of cortical target induced by prenatal ionizing irradiation: effects on the lateral geniculate nucleus and on the retinofugal pathways. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 19: 475-83. PMID 11378307 DOI: 10.1016/S0736-5748(00)00067-8  1
2001 Schmidt SL, Vitral RW, Linden R. Effects of prenatal ionizing irradiation on the development of the ganglion cell layer of the mouse retina. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 19: 469-73. PMID 11378306 DOI: 10.1016/S0736-5748(00)00068-X  1
2001 Guimarães C, Assreuy J, Linden R. Paracrine neuroprotective effect of nitric oxide in the developing retina. Journal of Neurochemistry. 76: 1233-41. PMID 11181842 DOI: 10.1046/j.1471-4159.2001.00126.x  1
2000 Chiarini LB, Linden R. Tissue biology of apoptosis. Ref-1 and cell differentiation in the developing retina. Annals of the New York Academy of Sciences. 926: 64-78. PMID 11193042  1
2000 Guimarães CA, Linden R. Chloramphenicol induces apoptosis in the developing brain. Neuropharmacology. 39: 1673-9. PMID 10854912 DOI: 10.1016/S0028-3908(99)00246-4  1
2000 de Ary-Pires R, Linden R. Laminin modulates neuritogenesis of developing rat retinal ganglion cells through a protein kinase C-dependent pathway. Journal of Neuroscience Research. 60: 291-301. PMID 10797531 DOI: 10.1002/(SICI)1097-4547(20000501)60:3<291::AID-JNR3>3.0.CO;2-Y  1
2000 Linden R. The anti-death league: associative control of apoptosis in developing retinal tissue. Brain Research. Brain Research Reviews. 32: 146-58. PMID 10751664 DOI: 10.1016/S0165-0173(99)00073-9  1
2000 Chiarini LB, Freitas FG, Petrs-Silva H, Linden R. Evidence that the bifunctional redox factor / AP endonuclease Ref-1 is an anti-apoptotic protein associated with differentiation in the developing retina. Cell Death and Differentiation. 7: 272-81. PMID 10745272 DOI: 10.1038/sj.cdd.4400639  1
1999 Rehen SK, Neves DD, Fragel-Madeira L, Britto LR, Linden R. Selective sensitivity of early postmitotic retinal cells to apoptosis induced by inhibition of protein synthesis. The European Journal of Neuroscience. 11: 4349-56. PMID 10594661 DOI: 10.1046/j.1460-9568.1999.00868.x  1
1999 Borges HL, Linden R. Gamma irradiation leads to two waves of apoptosis in distinct cell populations of the retina of newborn rats. Journal of Cell Science. 112: 4315-24. PMID 10564649  1
1999 Bosco A, Linden R. BDNF and NT-4 differentially modulate neurite outgrowth in developing retinal ganglion cells. Journal of Neuroscience Research. 57: 759-69. PMID 10467247 DOI: 10.1002/(SICI)1097-4547(19990915)57:6<759::AID-JNR1>3.0.CO;2-Y  1
1999 Linden R, Chiarini LB. Nuclear exclusion of transcription factors associated with apoptosis in developing nervous tissue. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 32: 813-20. PMID 10454738  1
1999 Varella MH, de Mello FG, Linden R. Evidence for an antiapoptotic role of dopamine in developing retinal tissue. Journal of Neurochemistry. 73: 485-92. PMID 10428043 DOI: 10.1046/j.1471-4159.1999.0730485.x  1
1999 Rocha M, Martins RA, Linden R. Activation of NMDA receptors protects against glutamate neurotoxicity in the retina: evidence for the involvement of neurotrophins. Brain Research. 827: 79-92. PMID 10320696  0.64
1999 Linden R, Rehen SK, Chiarini LB. Apoptosis in developing retinal tissue. Progress in Retinal and Eye Research. 18: 133-65. PMID 9932281 DOI: 10.1016/S1350-9462(98)00020-2  1
1997 Varella MH, Correa DF, Campos CB, Chiarini LB, Linden R. Protein kinases selectively modulate apoptosis in the developing retina in vitro. Neurochemistry International. 31: 217-27. PMID 9220454 DOI: 10.1016/S0197-0186(96)00151-9  1
1997 Ary-Pires R, Nakatani M, Rehen SK, Linden R. Developmentally regulated release of intraretinal neurotrophic factors in vitro. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 15: 239-55. PMID 9178042 DOI: 10.1016/S0736-5748(96)00087-1  1
1996 Linden R, Rehen SK, Chiarini LB, Nakatani M, Rocha M, Campos CB, Borges HL, Varella MH, Freitas FG, Correa DF, Guimarães CA. Death in a dish: controls of apoptosis within the developing retinal tissue. Revista Brasileira De Biologia. 56: 89-103. PMID 9394492  1
1996 Rehen SK, Varella MH, Freitas FG, Moraes MO, Linden R. Contrasting effects of protein synthesis inhibition and of cyclic AMP on apoptosis in the developing retina. Development (Cambridge, England). 122: 1439-48. PMID 8625832  1
1994 Bosco A, Linden R, Carri NG. Expression of alpha-1 integrin subunit in the mammalian retina. Cell Biology International. 18: 211-3. PMID 8019496 DOI: 10.1006/cbir.1994.1064  1
1994 Rehen SK, Linden R. Apoptosis in the developing retina: paradoxical effects of protein synthesis inhibition. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 27: 1647-51. PMID 7874031  1
1994 Serfaty CA, Linden R. Development of abnormal lamination and binocular segregation in the retinotectal pathways of the rat. Brain Research. Developmental Brain Research. 82: 35-44. PMID 7531121 DOI: 10.1016/0165-3806(94)90146-5  1
1993 Bosco A, Carri NG, Linden R. Neuritogenesis of retinal ganglion cells is differentially promoted by target extract. Brain Research. 632: 303-7. PMID 8149235 DOI: 10.1016/0006-8993(93)91165-O  1
1993 Rehen SK, Ary-Pires R, Linden R. Intraretinal neurotrophic activity prevents the degeneration of ganglion cells in retinal explants. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 26: 955-9. PMID 7905330  1
1992 Ary-Pires R, Rehen SK, Linden R. Evidence for a developmentally regulated neurotrophic activity from chick retina affecting the survival of retinal ganglion cells from newborn rats. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 25: 845-8. PMID 1342620  1
1991 Serfaty CA, Linden R. Evidence that the relative densities of afferents from both eyes control laminar distribution and binocular segregation of retinotectal projections in rats. Brain Research. Developmental Brain Research. 60: 9-17. PMID 1914147 DOI: 10.1016/0165-3806(91)90150-H  1
1991 Nakatani M, Linden R. Axon orientation and axo-dendritic polarity of retinal ganglion cells during postnatal development in the rat. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 24: 937-41. PMID 1797289  1
1990 Williams MA, Piñon LG, Linden R, Pinto LH. The pearl mutation accelerates the schedule of natural cell death in the early postnatal retina. Experimental Brain Research. 82: 393-400. PMID 2286240 DOI: 10.1007/BF00231258  1
1990 Serfaty CA, Linden R. Development of abnormal lamination and binocular segregation of retinal afferents onto the rat superior colliculus. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 23: 663-6. PMID 2101090  1
1990 Serfaty CA, Reese BE, Linden R. Cell death and interocular interactions among retinofugal axons: lack of binocularly matched specificity. Brain Research. Developmental Brain Research. 56: 198-204. PMID 1702041 DOI: 10.1016/0165-3806(90)90082-A  1
1987 Linden R, Piñon LG. Dual control by targets and afferents of developmental neuronal death in the mammalian central nervous system: a study in the parabigeminal nucleus of the rat. The Journal of Comparative Neurology. 266: 141-9. PMID 3437072 DOI: 10.1002/cne.902660202  1
1985 Linden R, Serfaty CA. Evidence for differential effects of terminal and dendritic competition upon developmental neuronal death in the retina. Neuroscience. 15: 853-68. PMID 4069356 DOI: 10.1016/0306-4522(85)90083-1  1
1984 Cavalcante LA, Rocha-Miranda CE, Linden R. Observations on postnatal neurogenesis in the superior colliculus and the pretectum in the opossum. Brain Research. 315: 241-9. PMID 6722588 DOI: 10.1016/0165-3806(84)90158-5  1
1983 Linden R, Rocha-Miranda CE. Organization of the visual thalamus: corticothalamic projections from the primary visual area in the opossum. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 16: 247-60. PMID 6652295  1
1981 Linden R, Rocha-Miranda CE. The pretectal complex in the opossum: projections from the striate cortex and correlation with retinal terminal fields. Brain Research. 207: 267-77. PMID 7470909 DOI: 10.1016/0006-8993(81)90364-4  1
1976 Rocha-Miranda CE, Linden R, Volchan E, Lent R, Bombar-Dieri RA. Receptive field properties of single units in the opossum striate cortex. Brain Research. 104: 197-219. PMID 816419 DOI: 10.1016/0049-3848(76)90263-2  1
1973 Rocha-Miranda CE, Bombardieri RA, de Monasterio FM, Linden R. Receptive fields in the visual cortex of the opossum. Brain Research. 63: 362-7. PMID 4764305 DOI: 10.1016/0006-8993(73)90105-4  1
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