Marc K. Jenkins - Publications

Affiliations: 
University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Immunology, Animal Physiology Biology, Microbiology Biology

204 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 McElwee MK, Dileepan T, Mahmud SA, Jenkins MK. The CD4+ T cell repertoire specific for citrullinated peptides shows evidence of immune tolerance. The Journal of Experimental Medicine. 220. PMID 37831103 DOI: 10.1084/jem.20230209  0.466
2023 Osum KC, Jenkins MK. Toward a general model of CD4 T cell subset specification and memory cell formation. Immunity. 56: 475-484. PMID 36921574 DOI: 10.1016/j.immuni.2023.02.010  0.58
2023 Nettersheim FS, Ghosheh Y, Winkels H, Kobiyama K, Durant C, Armstrong SS, Brunel S, Roy P, Dileepan T, Jenkins MK, Zajonc DM, Ley K. Single-cell transcriptomes and T cell receptors of vaccine-expanded apolipoprotein B-specific T cells. Frontiers in Cardiovascular Medicine. 9: 1076808. PMID 36684560 DOI: 10.3389/fcvm.2022.1076808  0.558
2022 Künzli M, O'Flanagan SD, LaRue M, Talukder P, Dileepan T, Stolley JM, Soerens AG, Quarnstrom CF, Wijeyesinghe S, Ye Y, McPartlan JS, Mitchell JS, Mandl CW, Vile R, Jenkins MK, et al. Route of self-amplifying mRNA vaccination modulates the establishment of pulmonary resident memory CD8 and CD4 T cells. Science Immunology. 7: eadd3075. PMID 36459542 DOI: 10.1126/sciimmunol.add3075  0.511
2022 Hong SW, Krueger PD, Osum KC, Dileepan T, Herman A, Mueller DL, Jenkins MK. Immune tolerance of food is mediated by layers of CD4 T cell dysfunction. Nature. PMID 35794484 DOI: 10.1038/s41586-022-04916-6  0.626
2022 Pape KA, Dileepan T, Matchett WE, Ellwood C, Stresemann S, Kabage AJ, Kozysa D, Evert C, Matson M, Lopez S, Krueger PD, Graiziger CT, Vaughn BP, Shmidt E, Rhein J, ... ... Jenkins MK, et al. Boosting corrects a memory B cell defect in SARS-CoV-2 mRNA-vaccinated patients with inflammatory bowel disease. Jci Insight. 7. PMID 35730567 DOI: 10.1172/jci.insight.159618  0.568
2021 Pape KA, Dileepan T, Kabage AJ, Kozysa D, Batres R, Evert C, Matson M, Lopez S, Krueger PD, Graiziger C, Vaughn BP, Shmidt E, Rhein J, Schacker TW, Khoruts A, ... Jenkins MK, et al. High-affinity memory B cells induced by SARS-CoV-2 infection produce more plasmablasts and atypical memory B cells than those primed by mRNA vaccines. Cell Reports. 37: 109823. PMID 34610291 DOI: 10.1016/j.celrep.2021.109823  0.556
2021 Nelson SA, Dileepan T, Rasley A, Jenkins MK, Fischer NO, Sant AJ. Intranasal nanoparticle vaccination elicits a persistent, polyfunctional CD4 T cell response in the murine lung specific for a highly conserved influenza antigen that are sufficient to mediate protection from influenza virus challenge. Journal of Virology. JVI0084121. PMID 34076479 DOI: 10.1128/JVI.00841-21  0.403
2021 Dileepan T, Malhotra D, Kotov DI, Kolawole EM, Krueger PD, Evavold BD, Jenkins MK. MHC class II tetramers engineered for enhanced binding to CD4 improve detection of antigen-specific T cells. Nature Biotechnology. PMID 33941928 DOI: 10.1038/s41587-021-00893-9  0.592
2021 Krueger PD, Osum KC, Jenkins MK. CD4 Memory T-Cell Formation during Type 1 Immune Responses. Cold Spring Harbor Perspectives in Biology. PMID 33903156 DOI: 10.1101/cshperspect.a038141  0.612
2021 Krueger PD, Goldberg MF, Hong SW, Osum KC, Langlois RA, Kotov DI, Dileepan T, Jenkins MK. Two sequential activation modules control the differentiation of protective T helper-1 (Th1) cells. Immunity. PMID 33773107 DOI: 10.1016/j.immuni.2021.03.006  0.547
2021 Joag V, Wijeyesinghe S, Stolley JM, Quarnstrom CF, Dileepan T, Soerens AG, Sangala JA, O'Flanagan SD, Gavil NV, Hong SW, Bhela S, Gangadhara S, Weyu E, Matchett WE, Thiede J, ... ... Jenkins MK, et al. Cutting Edge: Mouse SARS-CoV-2 Epitope Reveals Infection and Vaccine-Elicited CD8 T Cell Responses. Journal of Immunology (Baltimore, Md. : 1950). PMID 33441437 DOI: 10.4049/jimmunol.2001400  0.534
2021 Lee JH, Hu JK, Georgeson E, Nakao C, Groschel B, Dileepan T, Jenkins MK, Seumois G, Vijayanand P, Schief WR, Crotty S. Modulating the quantity of HIV Env-specific CD4 T cell help promotes rare B cell responses in germinal centers. The Journal of Experimental Medicine. 218. PMID 33355623 DOI: 10.1084/jem.20201254  0.588
2020 Malhotra D, Burrack KS, Jenkins MK, Frosch AE. Antigen-Specific CD4 T Cells Exhibit Distinct Kinetic and Phenotypic Patterns During Primary and Secondary Responses to Infection. Frontiers in Immunology. 11: 2125. PMID 32983171 DOI: 10.3389/Fimmu.2020.02125  0.698
2019 Hassler T, Urmann E, Teschner S, Federle C, Dileepan T, Schober K, Jenkins MK, Busch DH, Hinterberger M, Klein L. Inventories of naive and tolerant mouse CD4 T cell repertoires reveal a hierarchy of deleted and diverted T cell receptors. Proceedings of the National Academy of Sciences of the United States of America. PMID 31451631 DOI: 10.1073/Pnas.1907615116  0.721
2019 Vacchio MS, Ciucci T, Gao Y, Watanabe M, Balmaceno-Criss M, McGinty MT, Huang A, Xiao Q, McConkey C, Zhao Y, Shetty J, Tran B, Pepper M, Vahedi G, Jenkins MK, et al. A Thpok-Directed Transcriptional Circuitry Promotes Bcl6 and Maf Expression to Orchestrate T Follicular Helper Differentiation. Immunity. PMID 31422869 DOI: 10.1016/J.Immuni.2019.06.023  0.59
2019 Kotov JA, Kotov DI, Linehan JL, Bardwell VJ, Gearhart MD, Jenkins MK. BCL6 corepressor contributes to Th17 cell formation by inhibiting Th17 fate suppressors. The Journal of Experimental Medicine. PMID 31053612 DOI: 10.1084/Jem.20182376  0.815
2019 Kotov DI, Jenkins MK. Peptide:MHCII Tetramer-Based Cell Enrichment for the Study of Epitope-Specific CD4 T Cells. Current Protocols in Immunology. e75. PMID 31034767 DOI: 10.1002/Cpim.75  0.639
2019 Kotov DI, Mitchell JS, Pengo T, Ruedl C, Way SS, Langlois RA, Fife BT, Jenkins MK. TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2. Journal of Immunology (Baltimore, Md. : 1950). PMID 30858199 DOI: 10.4049/Jimmunol.1801609  0.637
2019 Kotov JA, Jenkins MK. Cutting Edge: T Cell-Dependent Plasmablasts Form in the Absence of Single Differentiated CD4 T Cell Subsets. Journal of Immunology (Baltimore, Md. : 1950). 202: 401-405. PMID 30552165 DOI: 10.4049/Jimmunol.1801349  0.655
2019 Kotov DI, Pengo T, Mitchell JS, Gastinger MJ, Jenkins MK. Chrysalis: A New Method for High-Throughput Histo-Cytometry Analysis of Images and Movies. Journal of Immunology (Baltimore, Md. : 1950). 202: 300-308. PMID 30510065 DOI: 10.4049/Jimmunol.1801202  0.31
2018 Goldberg MF, Roeske EK, Ward LN, Pengo T, Dileepan T, Kotov DI, Jenkins MK. Salmonella Persist in Activated Macrophages in T Cell-Sparse Granulomas but Are Contained by Surrounding CXCR3 Ligand-Positioned Th1 Cells. Immunity. 49: 1090-1102.e7. PMID 30552021 DOI: 10.1016/J.Immuni.2018.10.009  0.592
2018 Shore DE, Dileepan T, Modiano JF, Jenkins MK, Stadler BJH. Enrichment and Quantification of Epitope-specific CD4+ T Lymphocytes using Ferromagnetic Iron-gold and Nickel Nanowires. Scientific Reports. 8: 15696. PMID 30356071 DOI: 10.1038/S41598-018-33910-0  0.519
2018 Pape KA, Maul RW, Dileepan T, Paustian AS, Gearhart PJ, Jenkins MK. Naive B Cells with High-Avidity Germline-Encoded Antigen Receptors Produce Persistent IgM and Transient IgG Memory B Cells. Immunity. PMID 29884459 DOI: 10.1016/J.Immuni.2018.04.019  0.465
2018 Kimura T, Kobiyama K, Winkels H, Tse K, Miller J, Vassallo M, Wolf D, Ryden C, Orecchioni M, Dileepan T, Jenkins MK, James EA, Kwok WW, Hanna DB, Kaplan RC, et al. Regulatory CD4T Cells Recognize MHC-II-Restricted Peptide Epitopes of Apolipoprotein B. Circulation. PMID 29588316 DOI: 10.1161/Circulationaha.117.031420  0.559
2018 Kotov DI, Kotov JA, Goldberg MF, Jenkins MK. Many Th Cell Subsets Have Fas Ligand-Dependent Cytotoxic Potential. Journal of Immunology (Baltimore, Md. : 1950). PMID 29436413 DOI: 10.4049/Jimmunol.1700420  0.62
2017 Burrack AL, Malhotra D, Dileepan T, Osum KC, Swanson LA, Fife BT, Jenkins MK. Cutting Edge: Allograft Rejection Is Associated with Weak T Cell Responses to Many Different Graft Leukocyte-Derived Peptides. Journal of Immunology (Baltimore, Md. : 1950). PMID 29255075 DOI: 10.4049/Jimmunol.1701434  0.605
2017 Spanier JA, Sahli NL, Wilson JC, Martinov T, Dileepan T, Burrack AL, Finger EB, Blazar BR, Michels AW, Moran A, Jenkins MK, Fife BT. Increased Effector Memory Insulin-Specific CD4(+)T-cells Correlate with Insulin Autoantibodies in Recent-Onset Type 1 Diabetic Patients. Diabetes. PMID 28842400 DOI: 10.2337/Db17-0666  0.571
2017 Leonard JD, Gilmore DC, Dileepan T, Nawrocka WI, Chao JL, Schoenbach MH, Jenkins MK, Adams EJ, Savage PA. Identification of Natural Regulatory T Cell Epitopes Reveals Convergence on a Dominant Autoantigen. Immunity. PMID 28709804 DOI: 10.1016/J.Immuni.2017.06.015  0.532
2017 Pape KA, Jenkins MK. Do Memory B Cells Form Secondary Germinal Centers? It Depends. Cold Spring Harbor Perspectives in Biology. PMID 28320756 DOI: 10.1101/Cshperspect.A029116  0.481
2017 Farrar M, Hekim C, Luke MS, Vezys V, Jenkins MK. Overcoming Leukemia-Induced Immune Suppression in BCR-ABL+ Acute Lymphoblastic Leukemia Blood. 130: 3881-3881. DOI: 10.1182/Blood.V130.Suppl_1.3881.3881  0.585
2016 Schmiel SE, Yang JA, Jenkins MK, Mueller DL. Cutting Edge: Adenosine A2a Receptor Signals Inhibit Germinal Center T Follicular Helper Cell Differentiation during the Primary Response to Vaccination. Journal of Immunology (Baltimore, Md. : 1950). PMID 27986907 DOI: 10.4049/Jimmunol.1601686  0.694
2016 Karunakaran KP, Yu H, Jiang X, Chan Q, Goldberg MF, Jenkins MK, Foster LJ, Brunham RC. Identification of MHC-bound peptides from dendritic cells infected with Salmonella enterica strain SL1344: implications for a non-typhoidal Salmonella vaccine. Journal of Proteome Research. PMID 27802388 DOI: 10.1021/Acs.Jproteome.6B00926  0.517
2016 Spanier JA, Frederick DR, Taylor JJ, Heffernan JR, Kotov DI, Martinov T, Osum KC, Ruggiero JL, Rust BJ, Landry SJ, Jenkins MK, McLachlan JB, Fife BT. Efficient generation of monoclonal antibodies against peptide in the context of MHCII using magnetic enrichment. Nature Communications. 7: 11804. PMID 27292946 DOI: 10.1038/Ncomms11804  0.637
2016 Malhotra D, Jenkins MK. Regulatory T Cells: A Crisis Averted. Immunity. 44: 1079-81. PMID 27192571 DOI: 10.1016/J.Immuni.2016.04.025  0.506
2016 Beura LK, Hamilton SE, Bi K, Schenkel JM, Odumade OA, Casey KA, Thompson EA, Fraser KA, Rosato PC, Filali-Mouhim A, Sekaly RP, Jenkins MK, Vezys V, Haining WN, Jameson SC, et al. Normalizing the environment recapitulates adult human immune traits in laboratory mice. Nature. PMID 27096360 DOI: 10.1038/Nature17655  0.396
2016 Kalekar LA, Schmiel SE, Nandiwada SL, Lam WY, Barsness LO, Zhang N, Stritesky GL, Malhotra D, Pauken KE, Linehan JL, O'Sullivan MG, Fife BT, Hogquist KA, Jenkins MK, Mueller DL. CD4(+) T cell anergy prevents autoimmunity and generates regulatory T cell precursors. Nature Immunology. PMID 26829766 DOI: 10.1038/Ni.3331  0.871
2016 Tubo NJ, Fife BT, Pagan AJ, Kotov DI, Goldberg MF, Jenkins MK. Most microbe-specific naïve CD4⁺ T cells produce memory cells during infection. Science (New York, N.Y.). 351: 511-4. PMID 26823430 DOI: 10.1126/Science.Aad0483  0.844
2016 Malhotra D, Linehan JL, Dileepan T, Lee YJ, Purtha WE, Lu JV, Nelson RW, Fife BT, Orr HT, Anderson MS, Hogquist KA, Jenkins MK. Tolerance is established in polyclonal CD4(+) T cells by distinct mechanisms, according to self-peptide expression patterns. Nature Immunology. PMID 26726812 DOI: 10.1038/Ni.3327  0.845
2015 Linehan JL, Dileepan T, Kashem SW, Kaplan DH, Cleary P, Jenkins MK. Generation of Th17 cells in response to intranasal infection requires TGF-β1 from dendritic cells and IL-6 from CD301b+ dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. 112: 12782-7. PMID 26417101 DOI: 10.1073/Pnas.1513532112  0.816
2015 Manlove LS, Berquam-Vrieze KE, Pauken KE, Williams RT, Jenkins MK, Farrar MA. Adaptive Immunity to Leukemia Is Inhibited by Cross-Reactive Induced Regulatory T Cells. Journal of Immunology (Baltimore, Md. : 1950). 195: 4028-37. PMID 26378075 DOI: 10.4049/Jimmunol.1501291  0.675
2015 Nelson RW, Rajpal MN, Jenkins MK. The Neonatal CD4+ T Cell Response to a Single Epitope Varies in Genetically Identical Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 26179899 DOI: 10.4049/Jimmunol.1500405  0.645
2015 Yang JA, Tubo NJ, Gearhart MD, Bardwell VJ, Jenkins MK. Cutting edge: Bcl6-interacting corepressor contributes to germinal center T follicular helper cell formation and B cell helper function. Journal of Immunology (Baltimore, Md. : 1950). 194: 5604-8. PMID 25964495 DOI: 10.4049/Jimmunol.1500201  0.657
2015 Hwang S, Palin AC, Li L, Song KD, Lee J, Herz J, Tubo N, Chu H, Pepper M, Lesourne R, Zvezdova E, Pinkhasov J, Jenkins MK, McGavern D, Love PE. TCR ITAM multiplicity is required for the generation of follicular helper T-cells. Nature Communications. 6: 6982. PMID 25959494 DOI: 10.1038/Ncomms7982  0.646
2015 Moon JJ, Jenkins MK. The human T-cell repertoire grows up. Immunology and Cell Biology. 93: 601-2. PMID 25939281 DOI: 10.1038/Icb.2015.50  0.585
2015 Wüthrich M, Brandhorst TT, Sullivan TD, Filutowicz H, Sterkel A, Stewart D, Li M, Lerksuthirat T, LeBert V, Shen ZT, Ostroff G, Deepe GS, Hung CY, Cole G, Walter JA, ... Jenkins MK, et al. Calnexin induces expansion of antigen-specific CD4(+) T cells that confer immunity to fungal ascomycetes via conserved epitopes. Cell Host & Microbe. 17: 452-65. PMID 25800545 DOI: 10.1016/J.Chom.2015.02.009  0.629
2015 Pauken KE, Nelson CE, Martinov T, Spanier JA, Heffernan JR, Sahli NL, Quarnstrom CF, Osum KC, Schenkel JM, Jenkins MK, Blazar BR, Vezys V, Fife BT. Cutting edge: identification of autoreactive CD4+ and CD8+ T cell subsets resistant to PD-1 pathway blockade. Journal of Immunology (Baltimore, Md. : 1950). 194: 3551-5. PMID 25769925 DOI: 10.4049/Jimmunol.1402262  0.463
2015 Wiesner DL, Specht CA, Lee CK, Smith KD, Mukaremera L, Lee ST, Lee CG, Elias JA, Nielsen JN, Boulware DR, Bohjanen PR, Jenkins MK, Levitz SM, Nielsen K. Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection. Plos Pathogens. 11: e1004701. PMID 25764512 DOI: 10.1371/Journal.Ppat.1004701  0.566
2015 Lee JY, Skon CN, Lee YJ, Oh S, Taylor JJ, Malhotra D, Jenkins MK, Rosenfeld MG, Hogquist KA, Jameson SC. The transcription factor KLF2 restrains CD4⁺ T follicular helper cell differentiation. Immunity. 42: 252-64. PMID 25692701 DOI: 10.1016/J.Immuni.2015.01.013  0.772
2015 Taylor JJ, Pape KA, Steach HR, Jenkins MK. Humoral immunity. Apoptosis and antigen affinity limit effector cell differentiation of a single naïve B cell. Science (New York, N.Y.). 347: 784-7. PMID 25636798 DOI: 10.1126/Science.Aaa1342  0.736
2015 Nelson RW, Beisang D, Tubo NJ, Dileepan T, Wiesner DL, Nielsen K, Wüthrich M, Klein BS, Kotov DI, Spanier JA, Fife BT, Moon JJ, Jenkins MK. T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity. Immunity. 42: 95-107. PMID 25601203 DOI: 10.1016/J.Immuni.2014.12.022  0.522
2015 Nelson RW, Beisang D, Tubo NJ, Dileepan T, Wiesner DL, Nielsen K, Wüthrich M, Klein BS, Kotov DI, Spanier JA, Fife BT, Moon JJ, Jenkins MK. Erratum to T Cell Receptor Cross-Reactivity between Similar Foreign and Self Peptides Influences Naive Cell Population Size and Autoimmunity (Immunity 42, 95-107, 2015) Immunity. 42: 1212-1213. DOI: 10.1016/J.Immuni.2015.06.007  0.546
2014 Tubo NJ, Jenkins MK. TCR signal quantity and quality in CD4(+) T cell differentiation. Trends in Immunology. 35: 591-596. PMID 25457838 DOI: 10.1016/J.It.2014.09.008  0.681
2014 Jenkins MK. The in vivo response of naive CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 193: 3829-31. PMID 25281752 DOI: 10.4049/Jimmunol.1490035  0.539
2014 Yang Y, Torchinsky MB, Gobert M, Xiong H, Xu M, Linehan JL, Alonzo F, Ng C, Chen A, Lin X, Sczesnak A, Liao JJ, Torres VJ, Jenkins MK, Lafaille JJ, et al. Focused specificity of intestinal TH17 cells towards commensal bacterial antigens. Nature. 510: 152-6. PMID 24739972 DOI: 10.1038/Nature13279  0.848
2014 Tubo NJ, Jenkins MK. CD4+ T Cells: guardians of the phagosome. Clinical Microbiology Reviews. 27: 200-13. PMID 24696433 DOI: 10.1128/Cmr.00097-13  0.673
2014 Taylor JJ, Laudenbach M, Tucker AM, Jenkins MK, Pravetoni M. Hapten-specific naïve B cells are biomarkers of vaccine efficacy against drugs of abuse. Journal of Immunological Methods. 405: 74-86. PMID 24462800 DOI: 10.1016/J.Jim.2014.01.010  0.354
2013 Kearney ER, Pape KA, Loh DY, Jenkins MK. Pillars article: visualization of Peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity. 1994. 1: 327-339. Journal of Immunology (Baltimore, Md. : 1950). 191: 5327-39. PMID 24244027  0.402
2013 Pauken KE, Linehan JL, Spanier JA, Sahli NL, Kalekar LA, Binstadt BA, Moon JJ, Mueller DL, Jenkins MK, Fife BT. Cutting edge: type 1 diabetes occurs despite robust anergy among endogenous insulin-specific CD4 T cells in NOD mice. Journal of Immunology (Baltimore, Md. : 1950). 191: 4913-7. PMID 24123682 DOI: 10.4049/Jimmunol.1301927  0.803
2013 Tubo NJ, Pagán AJ, Taylor JJ, Nelson RW, Linehan JL, Ertelt JM, Huseby ES, Way SS, Jenkins MK. Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection. Cell. 153: 785-96. PMID 23663778 DOI: 10.1016/J.Cell.2013.04.007  0.862
2013 Pauken KE, Jenkins MK, Azuma M, Fife BT. PD-1, but not PD-L1, expressed by islet-reactive CD4+ T cells suppresses infiltration of the pancreas during type 1 diabetes. Diabetes. 62: 2859-69. PMID 23545706 DOI: 10.2337/Db12-1475  0.534
2013 Jenkins MK, Moon JJ. Response to comment on “The role of naive T cell precursor frequency and recruitment in dictating immune response magnitude”. Journal of Immunology (Baltimore, Md. : 1950). 190: 1896. PMID 23544199 DOI: 10.4049/Jimmunol.1290080  0.58
2013 Nelson RW, McLachlan JB, Kurtz JR, Jenkins MK. CD4+ T cell persistence and function after infection are maintained by low-level peptide:MHC class II presentation. Journal of Immunology (Baltimore, Md. : 1950). 190: 2828-34. PMID 23382562 DOI: 10.4049/Jimmunol.1202183  0.631
2013 Pagán AJ, Peters NC, Debrabant A, Ribeiro-Gomes F, Pepper M, Karp CL, Jenkins MK, Sacks DL. Tracking antigen-specific CD4+ T cells throughout the course of chronic Leishmania major infection in resistant mice. European Journal of Immunology. 43: 427-38. PMID 23109292 DOI: 10.1002/Eji.201242715  0.848
2013 Jenkins MK, Hedrick SM. Leo Lefrançois (1956–2013) Immunity. 39: 415-416. DOI: 10.1016/J.Immuni.2013.08.030  0.826
2012 Taylor JJ, Martinez RJ, Titcombe PJ, Barsness LO, Thomas SR, Zhang N, Katzman SD, Jenkins MK, Mueller DL. Deletion and anergy of polyclonal B cells specific for ubiquitous membrane-bound self-antigen. The Journal of Experimental Medicine. 209: 2065-77. PMID 23071255 DOI: 10.1084/Jem.20112272  0.702
2012 Carpenter AC, Grainger JR, Xiong Y, Kanno Y, Chu HH, Wang L, Naik S, dos Santos L, Wei L, Jenkins MK, O'Shea JJ, Belkaid Y, Bosselut R. The transcription factors Thpok and LRF are necessary and partly redundant for T helper cell differentiation. Immunity. 37: 622-33. PMID 23041065 DOI: 10.1016/J.Immuni.2012.06.019  0.599
2012 Taylor JJ, Jenkins MK, Pape KA. Heterogeneity in the differentiation and function of memory B cells. Trends in Immunology. 33: 590-7. PMID 22920843 DOI: 10.1016/J.It.2012.07.005  0.662
2012 Pagán AJ, Pepper M, Chu HH, Green JM, Jenkins MK. CD28 promotes CD4+ T cell clonal expansion during infection independently of its YMNM and PYAP motifs. Journal of Immunology (Baltimore, Md. : 1950). 189: 2909-17. PMID 22896637 DOI: 10.4049/Jimmunol.1103231  0.85
2012 Taniguchi RT, DeVoss JJ, Moon JJ, Sidney J, Sette A, Jenkins MK, Anderson MS. Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection. Proceedings of the National Academy of Sciences of the United States of America. 109: 7847-52. PMID 22552229 DOI: 10.1073/Pnas.1120607109  0.611
2012 Jenkins MK, Moon JJ. The role of naive T cell precursor frequency and recruitment in dictating immune response magnitude. Journal of Immunology (Baltimore, Md. : 1950). 188: 4135-40. PMID 22517866 DOI: 10.4049/Jimmunol.1102661  0.503
2012 Taylor JJ, Pape KA, Jenkins MK. A germinal center-independent pathway generates unswitched memory B cells early in the primary response. The Journal of Experimental Medicine. 209: 597-606. PMID 22370719 DOI: 10.1084/Jem.20111696  0.699
2012 Lee SJ, McLachlan JB, Kurtz JR, Fan D, Winter SE, Baumler AJ, Jenkins MK, McSorley SJ. Temporal expression of bacterial proteins instructs host CD4 T cell expansion and Th17 development. Plos Pathogens. 8: e1002499. PMID 22275869 DOI: 10.1371/Journal.Ppat.1002499  0.629
2012 Martinez RJ, Zhang N, Thomas SR, Nandiwada SL, Jenkins MK, Binstadt BA, Mueller DL. Arthritogenic self-reactive CD4+ T cells acquire an FR4hiCD73hi anergic state in the presence of Foxp3+ regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 170-81. PMID 22124124 DOI: 10.4049/Jimmunol.1101311  0.67
2011 Pepper M, Pagán AJ, Igyártó BZ, Taylor JJ, Jenkins MK. Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells. Immunity. 35: 583-95. PMID 22018468 DOI: 10.1016/J.Immuni.2011.09.009  0.858
2011 Dileepan T, Linehan JL, Moon JJ, Pepper M, Jenkins MK, Cleary PP. Robust antigen specific th17 T cell response to group A Streptococcus is dependent on IL-6 and intranasal route of infection. Plos Pathogens. 7: e1002252. PMID 21966268 DOI: 10.1371/Journal.Ppat.1002252  0.826
2011 Moon JJ, Dash P, Oguin TH, McClaren JL, Chu HH, Thomas PG, Jenkins MK. Quantitative impact of thymic selection on Foxp3+ and Foxp3- subsets of self-peptide/MHC class II-specific CD4+ T cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 14602-7. PMID 21873213 DOI: 10.1073/Pnas.1109806108  0.703
2011 Pepper M, Jenkins MK. Origins of CD4(+) effector and central memory T cells. Nature Immunology. 12: 467-71. PMID 21739668 DOI: 10.1038/Ni.2038  0.688
2011 Jenkins MK, Mueller D. On the trail of arthritogenic T cells. Arthritis and Rheumatism. 63: 2851-3. PMID 21567373 DOI: 10.1002/Art.30440  0.636
2011 Taylor JJ, Jenkins MK. CD4+ memory T cell survival. Current Opinion in Immunology. 23: 319-23. PMID 21524898 DOI: 10.1016/J.Coi.2011.03.010  0.787
2011 Pape KA, Taylor JJ, Maul RW, Gearhart PJ, Jenkins MK. Different B cell populations mediate early and late memory during an endogenous immune response. Science (New York, N.Y.). 331: 1203-7. PMID 21310965 DOI: 10.1126/Science.1201730  0.7
2011 Shelstad R, Shumway S, Jenkins M. 408 Inflammatory and Suppressive Graft Antigen-Specific CD4+ T Cells Co-Exist in Heart Allografts The Journal of Heart and Lung Transplantation. 30: S139-S140. DOI: 10.1016/J.Healun.2011.01.417  0.582
2010 Reiley WW, Shafiani S, Wittmer ST, Tucker-Heard G, Moon JJ, Jenkins MK, Urdahl KB, Winslow GM, Woodland DL. Distinct functions of antigen-specific CD4 T cells during murine Mycobacterium tuberculosis infection. Proceedings of the National Academy of Sciences of the United States of America. 107: 19408-13. PMID 20962277 DOI: 10.1073/Pnas.1006298107  0.683
2010 Chu HH, Moon JJ, Kruse AC, Pepper M, Jenkins MK. Negative selection and peptide chemistry determine the size of naive foreign peptide-MHC class II-specific CD4+ T cell populations. Journal of Immunology (Baltimore, Md. : 1950). 185: 4705-13. PMID 20861357 DOI: 10.4049/Jimmunol.1002276  0.544
2010 Winstead CJ, Reilly CS, Moon JJ, Jenkins MK, Hamilton SE, Jameson SC, Way SS, Khoruts A. CD4+CD25+Foxp3+ regulatory T cells optimize diversity of the conventional T cell repertoire during reconstitution from lymphopenia. Journal of Immunology (Baltimore, Md. : 1950). 184: 4749-60. PMID 20357265 DOI: 10.4049/Jimmunol.0904076  0.873
2010 Jenkins MK, Chu HH, McLachlan JB, Moon JJ. On the composition of the preimmune repertoire of T cells specific for Peptide-major histocompatibility complex ligands. Annual Review of Immunology. 28: 275-94. PMID 20307209 DOI: 10.1146/Annurev-Immunol-030409-101253  0.651
2010 Catron DM, Pape KA, Fife BT, van Rooijen N, Jenkins MK. A protease-dependent mechanism for initiating T-dependent B cell responses to large particulate antigens. Journal of Immunology (Baltimore, Md. : 1950). 184: 3609-17. PMID 20208013 DOI: 10.4049/Jimmunol.1000077  0.479
2010 Pepper M, Linehan JL, Pagán AJ, Zell T, Dileepan T, Cleary PP, Jenkins MK. Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells. Nature Immunology. 11: 83-9. PMID 19935657 DOI: 10.1038/Ni.1826  0.863
2010 Hogquist K, Chu HH, Moon JJ, Jenkins M, McHeyzer-Williams M, Nemazee D, Duong BH, Tian H, Ota T, Completo G, Han S, Vela JL, Ota M, Kubitz M, Bovin N, et al. Repertoire / Diversity (T and B) (SY3-3) Chairpersons: Masamichi Muramatsu, Kristin Hogquist International Immunology. 22. DOI: 10.1093/Intimm/Dxq286  0.479
2009 Jenkins MK, Schwartz RH. Pillars article: antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo. J. Exp. Med. 1987. 165: 302-319. Journal of Immunology (Baltimore, Md. : 1950). 183: 4150-67. PMID 19767565  0.742
2009 Chu HH, Moon JJ, Takada K, Pepper M, Molitor JA, Schacker TW, Hogquist KA, Jameson SC, Jenkins MK. Positive selection optimizes the number and function of MHCII-restricted CD4+ T cell clones in the naive polyclonal repertoire. Proceedings of the National Academy of Sciences of the United States of America. 106: 11241-5. PMID 19541603 DOI: 10.1073/Pnas.0902015106  0.546
2009 Moon JJ, Chu HH, Hataye J, Pagán AJ, Pepper M, McLachlan JB, Zell T, Jenkins MK. Tracking epitope-specific T cells. Nature Protocols. 4: 565-81. PMID 19373228 DOI: 10.1038/Nprot.2009.9  0.856
2009 McLachlan JB, Catron DM, Moon JJ, Jenkins MK. Dendritic cell antigen presentation drives simultaneous cytokine production by effector and regulatory T cells in inflamed skin. Immunity. 30: 277-88. PMID 19200757 DOI: 10.1016/J.Immuni.2008.11.013  0.621
2008 Burchill MA, Yang J, Vang KB, Moon JJ, Chu HH, Lio CW, Vegoe AL, Hsieh CS, Jenkins MK, Farrar MA. Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire. Immunity. 28: 112-21. PMID 18199418 DOI: 10.1016/J.Immuni.2007.11.022  0.681
2008 Yarke CA, Dalheimer SL, Zhang N, Catron DM, Jenkins MK, Mueller DL. Proliferating CD4+ T cells undergo immediate growth arrest upon cessation of TCR signaling in vivo. Journal of Immunology (Baltimore, Md. : 1950). 180: 156-62. PMID 18097015 DOI: 10.4049/Jimmunol.180.1.156  0.606
2008 Kedl RM, Teodorovic L, Haluszczak C, Jenkins M. The naïve CD8+ T cell pool contains a variable frequency of memory phenotype T cells bearing the signature of homeostatic expansion The Faseb Journal. 22: 355-355. DOI: 10.1096/Fasebj.22.2_Supplement.355  0.646
2007 Moon JJ, Chu HH, Pepper M, McSorley SJ, Jameson SC, Kedl RM, Jenkins MK. Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude. Immunity. 27: 203-13. PMID 17707129 DOI: 10.1016/J.Immuni.2007.07.007  0.695
2007 McLachlan JB, Jenkins MK. Migration and accumulation of effector CD4+ T cells in nonlymphoid tissues. Proceedings of the American Thoracic Society. 4: 439-42. PMID 17684285 DOI: 10.1513/pats.200606-137MS  0.638
2007 Ravindran R, Rusch L, Itano A, Jenkins MK, McSorley SJ. CCR6-dependent recruitment of blood phagocytes is necessary for rapid CD4 T cell responses to local bacterial infection. Proceedings of the National Academy of Sciences of the United States of America. 104: 12075-80. PMID 17615242 DOI: 10.1073/Pnas.0701363104  0.671
2007 Pape KA, Catron DM, Itano AA, Jenkins MK. The humoral immune response is initiated in lymph nodes by B cells that acquire soluble antigen directly in the follicles. Immunity. 26: 491-502. PMID 17379546 DOI: 10.1016/J.Immuni.2007.02.011  0.539
2007 Huddleston SJ, Ingulli E, Jenkins MK. Delayed gratification: A program of intimal hyperplasia progresses even as graft antigen-specific CD4+ T cells subside Journal of the American College of Surgeons. 205: S101. DOI: 10.1016/J.Jamcollsurg.2007.06.251  0.766
2007 Huddleston S, Hays W, Ingulli E, Jenkins M. 146: IFN-γ production by graft antigen specific CD4+ T cells is not required for the development of intimal hyerplasia The Journal of Heart and Lung Transplantation. 26: S112. DOI: 10.1016/J.Healun.2006.11.162  0.79
2006 Huddleston SJ, Hays WS, Filatenkov A, Ingulli E, Jenkins MK. CD154+ graft antigen-specific CD4+ T cells are sufficient for chronic rejection of minor antigen incompatible heart grafts. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 6: 1312-9. PMID 16686755 DOI: 10.1111/J.1600-6143.2006.01309.X  0.81
2006 Vanasek TL, Nandiwada SL, Jenkins MK, Mueller DL. CD25+Foxp3+ regulatory T cells facilitate CD4+ T cell clonal anergy induction during the recovery from lymphopenia. Journal of Immunology (Baltimore, Md. : 1950). 176: 5880-9. PMID 16670295 DOI: 10.4049/Jimmunol.176.10.5880  0.641
2006 Catron DM, Rusch LK, Hataye J, Itano AA, Jenkins MK. CD4+ T cells that enter the draining lymph nodes after antigen injection participate in the primary response and become central-memory cells. The Journal of Experimental Medicine. 203: 1045-54. PMID 16567390 DOI: 10.1084/Jem.20051954  0.881
2006 Hataye J, Moon JJ, Khoruts A, Reilly C, Jenkins MK. Naive and memory CD4+ T cell survival controlled by clonal abundance. Science (New York, N.Y.). 312: 114-6. PMID 16513943 DOI: 10.1126/Science.1124228  0.848
2005 Hippen KL, Schram BR, Tze LE, Pape KA, Jenkins MK, Behrens TW. In vivo assessment of the relative contributions of deletion, anergy, and editing to B cell self-tolerance. Journal of Immunology (Baltimore, Md. : 1950). 175: 909-16. PMID 16002689 DOI: 10.4049/Jimmunol.175.2.909  0.401
2005 Jenkins M. Tracking immune responses in vivo Arthritis Research & Therapy. 7: 1-1. DOI: 10.1186/Ar1510  0.681
2004 Park HS, Costalonga M, Reinhardt RL, Dombek PE, Jenkins MK, Cleary PP. Primary induction of CD4 T cell responses in nasal associated lymphoid tissue during group A streptococcal infection. European Journal of Immunology. 34: 2843-53. PMID 15368301 DOI: 10.1002/Eji.200425242  0.736
2004 Catron DM, Itano AA, Pape KA, Mueller DL, Jenkins MK. Visualizing the first 50 hr of the primary immune response to a soluble antigen. Immunity. 21: 341-7. PMID 15357945 DOI: 10.1016/J.Immuni.2004.08.007  0.591
2004 Khoruts A, Osness RE, Jenkins MK. IL-1 acts on antigen-presenting cells to enhance the in vivo proliferation of antigen-stimulated naive CD4 T cells via a CD28-dependent mechanism that does not involve increased expression of CD28 ligands. European Journal of Immunology. 34: 1085-90. PMID 15048719 DOI: 10.1002/Eji.200324170  0.707
2004 Richards DM, Dalheimer SL, Ehst BD, Vanasek TL, Jenkins MK, Hertz MI, Mueller DL. Indirect minor histocompatibility antigen presentation by allograft recipient cells in the draining lymph node leads to the activation and clonal expansion of CD4+ T cells that cause obliterative airways disease. Journal of Immunology (Baltimore, Md. : 1950). 172: 3469-79. PMID 15004147 DOI: 10.4049/Jimmunol.172.6.3469  0.838
2004 Germain RN, Jenkins MK. In vivo antigen presentation. Current Opinion in Immunology. 16: 120-5. PMID 14734120 DOI: 10.1016/J.Coi.2003.11.001  0.61
2003 Ehst BD, Ingulli E, Jenkins MK. Development of a novel transgenic mouse for the study of interactions between CD4 and CD8 T cells during graft rejection. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 3: 1355-62. PMID 14525595 DOI: 10.1046/J.1600-6135.2003.00246.X  0.828
2003 Reinhardt RL, Jenkins MK. Whole-body analysis of T cell responses. Current Opinion in Immunology. 15: 366-71. PMID 12900265 DOI: 10.1016/S0952-7915(03)00077-3  0.703
2003 Itano AA, Jenkins MK. Antigen presentation to naive CD4 T cells in the lymph node. Nature Immunology. 4: 733-9. PMID 12888794 DOI: 10.1038/Ni957  0.6
2003 Itano AA, McSorley SJ, Reinhardt RL, Ehst BD, Ingulli E, Rudensky AY, Jenkins MK. Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity. Immunity. 19: 47-57. PMID 12871638 DOI: 10.1016/S1074-7613(03)00175-4  0.85
2003 Pape KA, Kouskoff V, Nemazee D, Tang HL, Cyster JG, Tze LE, Hippen KL, Behrens TW, Jenkins MK. Visualization of the genesis and fate of isotype-switched B cells during a primary immune response. The Journal of Experimental Medicine. 197: 1677-87. PMID 12796466 DOI: 10.1084/Jem.20012065  0.508
2003 Reinhardt RL, Bullard DC, Weaver CT, Jenkins MK. Preferential accumulation of antigen-specific effector CD4 T cells at an antigen injection site involves CD62E-dependent migration but not local proliferation. The Journal of Experimental Medicine. 197: 751-62. PMID 12629067 DOI: 10.1084/Jem.20021690  0.786
2002 Ingulli E, Ulman DR, Lucido MM, Jenkins MK. In situ analysis reveals physical interactions between CD11b+ dendritic cells and antigen-specific CD4 T cells after subcutaneous injection of antigen. Journal of Immunology (Baltimore, Md. : 1950). 169: 2247-52. PMID 12193689 DOI: 10.4049/Jimmunol.169.5.2247  0.674
2002 Zell T, Jenkins MK. Flow cytometric analysis of T cell receptor signal transduction. Science's Stke : Signal Transduction Knowledge Environment. 2002: pl5. PMID 11972357 DOI: 10.1126/Stke.2002.128.Pl5  0.562
2002 McSorley SJ, Asch S, Costalonga M, Reinhardt RL, Jenkins MK. Tracking salmonella-specific CD4 T cells in vivo reveals a local mucosal response to a disseminated infection. Immunity. 16: 365-77. PMID 11911822 DOI: 10.1016/S1074-7613(02)00289-3  0.774
2001 Zell T, Khoruts A, Ingulli E, Bonnevier JL, Mueller DL, Jenkins MK. Single-cell analysis of signal transduction in CD4 T cells stimulated by antigen in vivo. Proceedings of the National Academy of Sciences of the United States of America. 98: 10805-10. PMID 11535838 DOI: 10.1073/Pnas.191567898  0.755
2001 Reichert P, Reinhardt RL, Ingulli E, Jenkins MK. Cutting edge: in vivo identification of TCR redistribution and polarized IL-2 production by naive CD4 T cells. Journal of Immunology (Baltimore, Md. : 1950). 166: 4278-81. PMID 11254679 DOI: 10.4049/Jimmunol.166.7.4278  0.745
2001 Jenkins MK, Khoruts A, Ingulli E, Mueller DL, McSorley SJ, Reinhardt RL, Itano A, Pape KA. In vivo activation of antigen-specific CD4 T cells. Annual Review of Immunology. 19: 23-45. PMID 11244029 DOI: 10.1146/Annurev.Immunol.19.1.23  0.86
2001 Reinhardt RL, Khoruts A, Merica R, Zell T, Jenkins MK. Visualizing the generation of memory CD4 T cells in the whole body. Nature. 410: 101-5. PMID 11242050 DOI: 10.1038/35065111  0.822
2001 Miga AJ, Masters SR, Durell BG, Gonzalez M, Jenkins MK, Maliszewski C, Kikutani H, Wade WF, Noelle RJ. Dendritic cell longevity and T cell persistence is controlled by CD154-CD40 interactions. European Journal of Immunology. 31: 959-65. PMID 11241301 DOI: 10.1002/1521-4141(200103)31:3<959::Aid-Immu959>3.0.Co;2-A  0.637
2000 McSorley SJ, Jenkins MK. Antibody is required for protection against virulent but not attenuated Salmonella enterica serovar typhimurium. Infection and Immunity. 68: 3344-8. PMID 10816483 DOI: 10.1128/Iai.68.6.3344-3348.2000  0.582
2000 Merica R, Khoruts A, Pape KA, Reinhardt RL, Jenkins MK. Antigen-experienced CD4 T cells display a reduced capacity for clonal expansion in vivo that is imposed by factors present in the immune host. Journal of Immunology (Baltimore, Md. : 1950). 164: 4551-7. PMID 10779756 DOI: 10.4049/Jimmunol.164.9.4551  0.834
2000 McSorley SJ, Cookson BT, Jenkins MK. Characterization of CD4+ T cell responses during natural infection with Salmonella typhimurium. Journal of Immunology (Baltimore, Md. : 1950). 164: 986-93. PMID 10623848 DOI: 10.4049/Jimmunol.164.2.986  0.629
1999 Curtsinger JM, Schmidt CS, Mondino A, Lins DC, Kedl RM, Jenkins MK, Mescher MF. Inflammatory cytokines provide a third signal for activation of naive CD4+ and CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 162: 3256-62. PMID 10092777  0.45
1999 Chen ZM, Jenkins MK. Clonal expansion of antigen-specific CD4 T cells following infection with Salmonella typhimurium is similar in susceptible (Itys) and resistant (Ityr) BALB/c mice. Infection and Immunity. 67: 2025-9. PMID 10085054 DOI: 10.1128/Iai.67.4.2025-2029.1999  0.57
1999 Pulendran B, Smith JL, Jenkins M, Schoenborn M, Maraskovsky E, Maliszewski CR. Prevention of peripheral tolerance by a dendritic cell growth factor: flt3 ligand as an adjuvant. The Journal of Experimental Medicine. 188: 2075-82. PMID 9841921 DOI: 10.1084/Jem.188.11.2075  0.54
1998 Pape KA, Khoruts A, Ingulli E, Mondino A, Merica R, Jenkins MK. Antigen-specific CD4+ T cells that survive after the induction of peripheral tolerance possess an intrinsic lymphokine production defect. Novartis Foundation Symposium. 215: 103-13; discussion 1. PMID 9760574 DOI: 10.1002/9780470515525.Ch8  0.81
1998 Malvey EN, Jenkins MK, Mueller DL. Peripheral immune tolerance blocks clonal expansion but fails to prevent the differentiation of Th1 cells. Journal of Immunology (Baltimore, Md. : 1950). 161: 2168-77. PMID 9725208  0.583
1998 Fang W, Weintraub BC, Dunlap B, Garside P, Pape KA, Jenkins MK, Goodnow CC, Mueller DL, Behrens TW. Self-reactive B lymphocytes overexpressing Bcl-xL escape negative selection and are tolerized by clonal anergy and receptor editing. Immunity. 9: 35-45. PMID 9697834 DOI: 10.1016/S1074-7613(00)80586-5  0.423
1998 Garside P, Ingulli E, Merica RR, Johnson JG, Noelle RJ, Jenkins MK. Visualization of specific B and T lymphocyte interactions in the lymph node. Science (New York, N.Y.). 281: 96-9. PMID 9651253 DOI: 10.1126/Science.281.5373.96  0.617
1998 Hathcock KS, Weng NP, Merica R, Jenkins MK, Hodes R. Cutting edge: antigen-dependent regulation of telomerase activity in murine T cells. Journal of Immunology (Baltimore, Md. : 1950). 160: 5702-6. PMID 9637478  0.512
1998 Pape KA, Merica R, Mondino A, Khoruts A, Jenkins MK. Direct evidence that functionally impaired CD4+ T cells persist in vivo following induction of peripheral tolerance. Journal of Immunology (Baltimore, Md. : 1950). 160: 4719-29. PMID 9590217  0.596
1998 Chen ZM, Jenkins MK. Revealing the in vivo behavior of CD4+ T cells specific for an antigen expressed in Escherichia coli. Journal of Immunology (Baltimore, Md. : 1950). 160: 3462-70. PMID 9531307  0.579
1998 Zhang ZQ, Notermans DW, Sedgewick G, Cavert W, Wietgrefe S, Zupancic M, Gebhard K, Henry K, Boies L, Chen Z, Jenkins M, Mills R, McDade H, Goodwin C, Schuwirth CM, et al. Kinetics of CD4+ T cell repopulation of lymphoid tissues after treatment of HIV-1 infection. Proceedings of the National Academy of Sciences of the United States of America. 95: 1154-9. PMID 9448301 DOI: 10.1073/Pnas.95.3.1154  0.611
1998 Khoruts A, Mondino A, Pape KA, Reiner SL, Jenkins MK. A natural immunological adjuvant enhances T cell clonal expansion through a CD28-dependent, interleukin (IL)-2-independent mechanism. The Journal of Experimental Medicine. 187: 225-36. PMID 9432980 DOI: 10.1084/Jem.187.2.225  0.756
1998 Pape KA, Jenkins MK. A role for inflammatory cytokines in the productive activation of antigen-specific CD4+ T-cells. Agents and Actions. Supplements. 49: 23-31. PMID 9426825  0.618
1998 Ingulli E, Garside P, Jenkins M. VISUALIZATION OF ANTIGEN-SPECIFIC CD4+ T CELL-B CELL INTERACTION DURING A PRIMARY IMMUNE RESPONSEIN VIVO. Transplantation. 65: 86. DOI: 10.1097/00007890-199805131-00029  0.633
1997 Blazar BR, Jenkins MK, Taylor PA, White J, Panoskaltsis-Mortari A, Korngold R, Vallera DA. Anti-CD3 epsilon F(ab')2 fragments inhibit T cell expansion in vivo during graft-versus-host disease or the primary immune response to nominal antigen. Journal of Immunology (Baltimore, Md. : 1950). 159: 5821-33. PMID 9550378  0.596
1997 Pape KA, Khoruts A, Mondino A, Jenkins MK. Inflammatory cytokines enhance the in vivo clonal expansion and differentiation of antigen-activated CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 159: 591-8. PMID 9218573  0.552
1997 Hautamaa D, Merica R, Chen Z, Jenkins MK. Murine lymphotactin: gene structure, post-translational modification and inhibition of expression by CD28 costimulation. Cytokine. 9: 375-82. PMID 9199871 DOI: 10.1006/Cyto.1996.0179  0.562
1997 Ingulli E, Mondino A, Khoruts A, Jenkins MK. In vivo detection of dendritic cell antigen presentation to CD4(+) T cells. The Journal of Experimental Medicine. 185: 2133-41. PMID 9182685 DOI: 10.1084/Jem.185.12.2133  0.767
1997 Pape KA, Kearney ER, Khoruts A, Mondino A, Merica R, Chen ZM, Ingulli E, White J, Johnson JG, Jenkins MK. Use of adoptive transfer of T-cell-antigen-receptor-transgenic T cell for the study of T-cell activation in vivo. Immunological Reviews. 156: 67-78. PMID 9176700 DOI: 10.1111/J.1600-065X.1997.Tb00959.X  0.8
1997 Mueller DL, Jenkins MK. Autoimmunity: When self-tolerance breaks down Current Biology. 7: R255-R257. PMID 9162505 DOI: 10.1016/S0960-9822(06)00115-1  0.511
1996 Mondino A, Whaley CD, DeSilva DR, Li W, Jenkins MK, Mueller DL. Defective Transcription of the IL-2 Gene Is Associated with Impaired Expression of c-Fos, FosB, and JunB in Anergic T Helper 1 Cells Journal of Immunology. 157: 2048-2057. PMID 8757326  0.448
1996 Mondino A, Khoruts A, Jenkins MK. The anatomy of T-cell activation and tolerance Proceedings of the National Academy of Sciences of the United States of America. 93: 2245-2252. PMID 8637857 DOI: 10.1073/Pnas.93.6.2245  0.776
1996 Khoruts A, Jenkins MK. Studying immunological tolerance by physically monitoring antigen-specific T cells in vivo Annals of the New York Academy of Sciences. 778: 72-79. PMID 8611018 DOI: 10.1111/J.1749-6632.1996.Tb21116.X  0.744
1996 LOU J, BLUMENTHAL M, CHEN Z, JENKINS M. 249 Antigen-specific T cells are activated at early times following antigen inhalation Journal of Allergy and Clinical Immunology. 97: 245-245. DOI: 10.1016/S0091-6749(96)80467-2  0.501
1996 Kellermann SA, Jenkins MK, Shimizu Y. Regulation of adhesion molecule expression by t cell activation in vivo Faseb Journal. 10: A1456.  0.418
1995 Khoruts A, Miller SD, Jenkins MK. Neuroantigen-specific Th2 cells are inefficient suppressors of experimental autoimmune encephalomyelitis induced by effector Th1 cells Journal of Immunology. 155: 5011-5017. PMID 7594508  0.394
1995 Mondino A, Jenkins MK. Accumulation of sequence-specific RNA-binding proteins in the cytosol of activated T cells undergoing RNA degradation and apoptosis Journal of Biological Chemistry. 270: 26593-26601. PMID 7592882 DOI: 10.1074/Jbc.270.44.26593  0.429
1995 Mueller DL, Jenkins MK. Molecular mechanisms underlying functional T-cell unresponsiveness Current Opinion in Immunology. 7: 375-381. PMID 7546403 DOI: 10.1016/0952-7915(95)80113-8  0.575
1995 Kearney ER, Walunas TL, Karr RW, Morton PA, Loh DY, Bluestone JA, Jenkins MK. Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4 Journal of Immunology. 155: 1032-1036. PMID 7543510  0.579
1994 Urdahl KB, Pardoll DM, Jenkins MK. Cyclosporin A inhibits positive selection and delays negative selection in αβ TCR transgenic mice Journal of Immunology. 152: 2853-2859. PMID 8144886  0.349
1994 Granger DK, Matas AJ, Jenkins MK, Moss AA, Chen SC, Almond PS, Ascher NL. Prolonged survival without posttransplant immunosuppression in a large animal model Surgery. 116: 236-241. PMID 8047990  0.57
1994 Johnson JG, Jenkins MK. Minireview The role of anergy in peripheral T cell unresponsiveness Life Sciences. 55: 1767-1780. PMID 7968257 DOI: 10.1016/0024-3205(94)90087-6  0.688
1994 Mondino A, Jenkins MK. Surface proteins involved in T cell costimulation Journal of Leukocyte Biology. 55: 805-815. PMID 7910841 DOI: 10.1002/Jlb.55.6.805  0.69
1994 Kearney ER, Pape KA, Loh DY, Jenkins MK. Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo Immunity. 1: 327-339. PMID 7889419 DOI: 10.1016/1074-7613(94)90084-1  0.569
1994 Jenkins MK. The ups and downs of T cell costimulation Immunity. 1: 443-446. PMID 7534615 DOI: 10.1016/1074-7613(94)90086-8  0.648
1994 Johnson JG, Jenkins MK. Monocytes provide a novel costimulatory signal to T cells that is not mediated by the CD28/B7 interaction Journal of Immunology. 152: 429-437. PMID 7506722  0.56
1993 Kelner GS, Minnerath JM, Jenkins MK, Jemmerson R. The murine immune response to the male-specific antigen mouse testicular cytochrome c European Journal of Immunology. 23: 1992-1998. PMID 8393801 DOI: 10.1002/Eji.1830230840  0.511
1993 Jenkins MK, DeSilva DR, Johnson JG, Norton SD. Costimulating factors and signals relevant for antigen presenting cell function Advances in Experimental Medicine and Biology. 329: 87-92. PMID 8104378 DOI: 10.1007/978-1-4615-2930-9_15  0.662
1993 Johnson JG, Jenkins MK. Accessory cell-derived signals required for T cell activation Immunologic Research. 12: 48-64. PMID 8099942 DOI: 10.1007/Bf02918368  0.692
1993 Jenkins MK, Johnson JG. Molecules involved in T-cell costimulation Current Opinion in Immunology. 5: 361-367. PMID 7688514 DOI: 10.1016/0952-7915(93)90054-V  0.665
1993 Kelner GS, Jenkins MK, Jemmerson R. A single amino acid substitution in a cytochrome c T cell stimulatory peptide changes the MHC restriction element from one isotype (I-Ak) to another (I-Ek) Molecular Immunology. 30: 569-575. PMID 7683749 DOI: 10.1016/0161-5890(93)90031-6  0.36
1992 Jenkins MK, Miller RA. Memory and anergy: Challenges to traditional models of T lymphocyte differentiation Faseb Journal. 6: 2428-2433. PMID 1563595 DOI: 10.1096/Fasebj.6.7.1563595  0.649
1992 Norton SD, Zuckerman L, Urdahl KB, Shefner R, Miller J, Jenkins MK. The CD28 ligand, B7, enhances IL-2 production by providing a costimulatory signal to T cells. Journal of Immunology (Baltimore, Md. : 1950). 149: 1556-61. PMID 1380533  0.575
1992 Johnson JG, Jenkins MK. Co-Stimulatory functions of antigen-presenting cells Journal of Investigative Dermatology. 99: 62-65. PMID 1358981 DOI: 10.1111/1523-1747.Ep12669010  0.664
1992 Jenkins MK. The role of cell division in the induction of clonal anergy Immunology Today. 13: 69-73. PMID 1349483 DOI: 10.1016/0167-5699(92)90137-V  0.417
1992 Pardoll DM, Jenkins MK. Self-reactive t cells are present in the peripheral lymphoid tissues of cyclosporin a-treated mice International Immunology. 4: 1341-1349. PMID 1286060 DOI: 10.1093/Intimm/4.12.1341  0.595
1991 Leonard BAB, Lee PK, Jenkins MK, Schlievert PM. Cell and receptor requirements for streptococcal pyrogenic exotoxin T-cell mitogenicity Infection and Immunity. 59: 1210-1214. PMID 1997426 DOI: 10.1128/Iai.59.3.1210-1214.1991  0.587
1991 Jenkins MK, Mueller D, Schwartz RH, Carding S, Bottomley K, Stadecker MJ, Urdahl KB, Norton SD. Induction and maintenance of anergy in mature T cells Advances in Experimental Medicine and Biology. 292: 167-176. PMID 1950767 DOI: 10.1007/978-1-4684-5943-2_19  0.659
1991 Jemmerson R, Johnson JG, Burrell E, Taylor PS, Jenkins MK. A monoclonal antibody specific for a cytochrome c T cell stimulatory peptide inhibits T cell responses and affects the way the peptide associates with antigen-presenting cells. European Journal of Immunology. 21: 143-51. PMID 1846813 DOI: 10.1002/Eji.1830210122  0.45
1991 Jenkins MK, Taylor PS, Norton SD, Urdahl KB. CD28 delivers a costimulatory signal involved in antigen-specific IL-2 production by human T cells. Journal of Immunology (Baltimore, Md. : 1950). 147: 2461-6. PMID 1717561  0.558
1991 Urdahl KB, Jenkins MK, Norton SD. Accessory cell-derived costimulatory signals regulate T cell proliferation Annals of the New York Academy of Sciences. 636: 33-42. PMID 1665322 DOI: 10.1111/J.1749-6632.1991.Tb33436.X  0.662
1991 DeSilva DR, Urdahl KB, Jenkins MK. Clonal anergy is induced in vitro by T cell receptor occupancy in the absence of proliferation Journal of Immunology. 147: 3261-3267. PMID 1658142  0.435
1991 Leonard BA, Lee PK, Jenkins MK, Schlievert PM. Cell and receptor requirements for streptococcal pyrogenic exotoxin T-cell mitogenicity. Infection and Immunity. 59: 1210-1214. DOI: 10.1128/iai.59.3.1210-1214.1991  0.531
1990 Norton SD, Schlievert PM, Novick RP, Jenkins MK. Molecular requirements for T cell activation by the staphylococcal toxic shock syndrome toxin-1 Journal of Immunology. 144: 2089-2095. PMID 2313089  0.476
1990 Jenkins MK, Burrell E, Ashwell JD. Antigen presentation by resting B cells: Effectiveness at inducing T cell proliferation is determined by costimulatory signals, not T cell receptor occupancy Journal of Immunology. 144: 1585-1590. PMID 2307834  0.579
1990 Jenkins MK, Chen C, Jung G, Mueller DL, Schwartz RH. Inhibition of antigen-specific proliferation of type 1 murine T cell clones after stimulation with immobilized anti-CD3 monoclonal antibody Journal of Immunology. 144: 16-22. PMID 2153162  0.511
1990 Mueller DL, Jenkins MK, Chiodetti L, Schwartz RH. An intracellular calcium increase and protein kinase C activation fail to initiate T cell proliferation in the absence of a costimulatory signal Journal of Immunology. 144: 3701-3709. PMID 1970590  0.508
1989 Mueller DL, Jenkins MK, Schwartz RH. Clonal expansion versus functional clonal inactivation: A costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy Annual Review of Immunology. 7: 445-480. PMID 2653373 DOI: 10.1146/Annurev.Iy.07.040189.002305  0.436
1989 Schwartz RH, Mueller DL, Jenkins MK, Quill H. T-cell clonal anergy Cold Spring Harbor Symposia On Quantitative Biology. 54: 605-610. PMID 2534840 DOI: 10.1101/Sqb.1989.054.01.072  0.646
1989 Mueller DL, Jenkins MK, Schwartz RH. An accessory cell-derived costimulatory signal acts independently of protein kinase C activation to allow T cell proliferation and prevent the induction of unresponsiveness Journal of Immunology. 142: 2617-2628. PMID 2522963  0.496
1988 Jenkins MK, Schwartz RH, Pardoll DM. Effects of cyclosporine A on T cell development and clonal deletion Science. 241: 1655-1658. PMID 3262237 DOI: 10.1126/Science.3262237  0.653
1988 Ashwell JD, Jenkins MK, Schwartz RH. Effect of gamma radiation on resting B lymphocytes. II. Functional characterization of the antigen-presentation defect Journal of Immunology. 141: 2536-2544. PMID 2844902  0.405
1988 Jenkins MK, Ashwell JD, Schwartz RH. Allogeneic non-T spleen cells restore the responsiveness of normal T cell clones stimulated with antigen and chemically modified antigen-presenting cells Journal of Immunology. 140: 3324-3330. PMID 2834436  0.586
1988 Gaspari AA, Jenkins MK, Katz SI. Class II MHC-bearing keratinocytes induce antigen-specific unresponsiveness in hapten-specific Th1 clones Journal of Immunology. 141: 2216-2220. PMID 2459202  0.509
1987 Stuart PM, Iannaccone PM, Miller SD, Jenkins MK, Del Muro FA, Melvold RW. In vitro and in vivo correlates of hybrid tumor resistance Journal of the National Cancer Institute. 78: 1159-1168. PMID 3495687 DOI: 10.1093/Jnci/78.6.1159  0.309
1987 Jenkins MK, Schwartz RH. Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo Journal of Experimental Medicine. 165: 302-319. PMID 3029267 DOI: 10.1084/Jem.165.2.302  0.661
1987 Jenkins MK, Pardoll DM, Mizuguchi J, Chused TM, Schwartz RH. Molecular events in the induction of a nonresponsive state in interleukin 2-producing helper T-lymphocyte clones Proceedings of the National Academy of Sciences of the United States of America. 84: 5409-5413. PMID 2955418 DOI: 10.1073/Pnas.84.15.5409  0.518
1987 Jenkins MK, Pardoll DM, Mizuguchi J, Quill H, Schwartz RH. T-cell unresponsiveness in vivo and in vitro: fine specificity of induction and molecular characterization of the unresponsive state Immunological Reviews. 95: 113-135. PMID 2437012 DOI: 10.1111/J.1600-065X.1987.Tb00502.X  0.558
1986 Kennedy MK, Jenkins MK, Miller SD. Mechanisms of genetic control of immune responses - II. Nonresponsiveness in BALB/c GT-specific cell-mediated immune responses does not correlate with the absence of functional T cells or the induction of suppressor T cells Immunogenetics. 23: 292-301. PMID 2423450 DOI: 10.1007/Bf00398791  0.459
1986 Miller SD, Jenkins MK. Suppressor T cell circuits in contact sensitivity. III. A monoclonal T cell hybrid-derived suppressor factor specifically suppresses local DTH transfer by a DNP-specific T cell clone Journal of Immunology. 136: 1571-1578. PMID 2419406  0.585
1985 Jenkins MK, Waltenbaugh C, Miller SD. Immunoregulatory pathways in adult responder mice. II. Regulation of delayed-type hypersensitivity responses by GAT-specific suppressor factors present in GAT-tolerant adult responder mice Journal of Immunology. 134: 114-121. PMID 3155459  0.433
1985 Jenkins MK, Miller SD. Immunoregulatory pathways in adult responder mice. III. Establishment of a GAT-specific suppressor T cell clone from GAT-tolerant responders which afferently regulates DTH responses Journal of Molecular and Cellular Immunology. 2: 1-13. PMID 2978221  0.397
1985 Miller SD, Jenkins MK. In vivo effects of GK1.5 (anti-L3T4a) monoclonal antibody on induction and expression of delayed-type hypersensitivity Cellular Immunology. 92: 414-426. PMID 2859929 DOI: 10.1016/0008-8749(85)90022-X  0.604
1984 Jenkins MK, Lei HY, Waltenbaugh C, Miller SD. Immunoregulatory pathways in adult responder mice. I. Induction of GAT-specific tolerance and suppressor T cells for cellular and humoral responses Scandinavian Journal of Immunology. 19: 501-512. PMID 6204374 DOI: 10.1111/J.1365-3083.1984.Tb00961.X  0.561
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