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Amy L. McNulty, Ph.D. - Publications

Affiliations: 
2005 Duke University, Durham, NC 
Area:
Cell Biology, Pathology, Molecular Biology
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Andress BD, Irwin RM, Puranam I, Hoffman BD, McNulty AL. A Tale of Two Loads: Modulation of IL-1 Induced Inflammatory Responses of Meniscal Cells in Two Models of Dynamic Physiologic Loading. Frontiers in Bioengineering and Biotechnology. 10: 837619. PMID 35299636 DOI: 10.3389/fbioe.2022.837619  0.335
2021 Lee W, Nims RJ, Savadipour A, Zhang Q, Leddy HA, Liu F, McNulty AL, Chen Y, Guilak F, Liedtke WB. Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33758095 DOI: 10.1073/pnas.2001611118  0.322
2020 Lyons LP, Weinberg JB, Wittstein J, McNulty AL. Blood in the Joint: Effects of Hemarthrosis on Meniscus Health and Repair Techniques. Osteoarthritis and Cartilage. PMID 33307179 DOI: 10.1016/j.joca.2020.11.008  0.333
2019 Lyons LP, Hidalgo Perea S, Weinberg JB, Wittstein JR, McNulty AL. Meniscus-Derived Matrix Bioscaffolds: Effects of Concentration and Cross-Linking on Meniscus Cellular Responses and Tissue Repair. International Journal of Molecular Sciences. 21. PMID 31861690 DOI: 10.3390/Ijms21010044  0.406
2019 Hidalgo Perea S, Lyons LP, Nishimuta JF, Weinberg JB, McNulty AL. Evaluation of culture conditions for meniscus repair model systems using bone marrow-derived mesenchymal stem cells. Connective Tissue Research. 1-16. PMID 31661326 DOI: 10.1080/03008207.2019.1680656  0.386
2019 Ruprecht JC, Waanders TD, Rowland CR, Nishimuta JF, Glass KA, Stencel J, DeFrate LE, Guilak F, Weinberg JB, McNulty AL. Meniscus-Derived Matrix Scaffolds Promote the Integrative Repair of Meniscal Defects. Scientific Reports. 9: 8719. PMID 31213610 DOI: 10.1038/S41598-019-44855-3  0.422
2018 Collins AT, Hatcher CC, Kim SY, Ziemian SN, Spritzer CE, Guilak F, DeFrate LE, McNulty AL. Selective Enzymatic Digestion of Proteoglycans and Collagens Alters Cartilage T1rho and T2 Relaxation Times. Annals of Biomedical Engineering. PMID 30288634 DOI: 10.1007/S10439-018-02143-7  0.337
2017 Furman BD, Kent CL, Huebner JL, Kraus VB, McNulty AL, Guilak F, Olson SA. CXCL10 is Upregulated in Synovium and Cartilage following Articular Fracture. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 28906016 DOI: 10.1002/Jor.23735  0.544
2017 Liu B, Lad NK, Collins AT, Ganapathy PK, Utturkar GM, McNulty AL, Spritzer CE, Moorman CT, Sutter EG, Garrett WE, DeFrate LE. In Vivo Tibial Cartilage Strains in Regions of Cartilage-to-Cartilage Contact and Cartilage-to-Meniscus Contact in Response to Walking. The American Journal of Sports Medicine. 363546517712506. PMID 28671850 DOI: 10.1177/0363546517712506  0.398
2017 Hatcher CC, Collins AT, Kim SY, Michel LC, Mostertz WC, Ziemian SN, Spritzer CE, Guilak F, DeFrate LE, McNulty AL. Relationship between T1rho magnetic resonance imaging, synovial fluid biomarkers, and the biochemical and biomechanical properties of cartilage. Journal of Biomechanics. PMID 28237185 DOI: 10.1016/J.Jbiomech.2017.02.001  0.408
2016 Liu B, Goode AP, Carter TE, Utturkar GM, Huebner JL, Taylor DC, Moorman Iii CT, Garrett WE, Kraus VB, Guilak F, DeFrate LE, McNulty AL. Matrix Metalloproteinase Activity and Prostaglandin E2 are Elevated in the Synovial Fluid of Meniscus Tear Patients. Connective Tissue Research. PMID 27813662 DOI: 10.1080/03008207.2016.1256391  0.516
2016 O'Conor CJ, Ramalingam S, Zelenski NA, Benefield HC, Rigo I, Little D, Wu CL, Chen D, Liedtke W, McNulty AL, Guilak F. Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis. Scientific Reports. 6: 29053. PMID 27388701 DOI: 10.1038/Srep29053  0.424
2016 Cucchiarini M, McNulty AL, Mauck RL, Setton LA, Guilak F, Madry H. Advances in combining gene therapy with cell and tissue engineering-based approaches to enhance healing of the meniscus. Osteoarthritis and Cartilage. 24: 1330-9. PMID 27063441 DOI: 10.1016/J.Joca.2016.03.018  0.365
2016 Lee W, Leddy H, McNulty A, Guilak F, Liedtke W. Inflammatory Cytokine Il-1α Up-Regulates Piezo1 and Hyper-Sensitizes Chondrocytes to Compression Biophysical Journal. 110: 349a. DOI: 10.1016/J.Bpj.2015.11.1878  0.428
2015 Carter TE, Taylor KA, Spritzer CE, Utturkar GM, Taylor DC, Moorman CT, Garrett WE, Guilak F, McNulty AL, DeFrate LE. In vivo cartilage strain increases following medial meniscal tear and correlates with synovial fluid matrix metalloproteinase activity. Journal of Biomechanics. 48: 1461-8. PMID 25801424 DOI: 10.1016/J.Jbiomech.2015.02.030  0.441
2015 McNulty AL, Guilak F. Mechanobiology of the meniscus. Journal of Biomechanics. 48: 1469-78. PMID 25731738 DOI: 10.1016/J.Jbiomech.2015.02.008  0.408
2015 McNulty AL, Leddy HA, Liedtke W, Guilak F. TRPV4 as a therapeutic target for joint diseases. Naunyn-Schmiedeberg's Archives of Pharmacology. 388: 437-50. PMID 25519495 DOI: 10.1007/S00210-014-1078-X  0.42
2014 Lee W, Leddy HA, Chen Y, Lee SH, Zelenski NA, McNulty AL, Wu J, Beicker KN, Coles J, Zauscher S, Grandl J, Sachs F, Guilak F, Liedtke WB. Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage. Proceedings of the National Academy of Sciences of the United States of America. 111: E5114-22. PMID 25385580 DOI: 10.1073/Pnas.1414298111  0.407
2014 Sanchez-Adams J, Leddy HA, McNulty AL, O'Conor CJ, Guilak F. The mechanobiology of articular cartilage: bearing the burden of osteoarthritis. Current Rheumatology Reports. 16: 451. PMID 25182679 DOI: 10.1007/S11926-014-0451-6  0.47
2013 McNulty AL, Rothfusz NE, Leddy HA, Guilak F. Synovial fluid concentrations and relative potency of interleukin-1 alpha and beta in cartilage and meniscus degradation. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 31: 1039-45. PMID 23483596 DOI: 10.1002/Jor.22334  0.375
2011 Riera KM, Rothfusz NE, Wilusz RE, Weinberg JB, Guilak F, McNulty AL. Interleukin-1, tumor necrosis factor-alpha, and transforming growth factor-beta 1 and integrative meniscal repair: influences on meniscal cell proliferation and migration. Arthritis Research & Therapy. 13: R187. PMID 22087734 DOI: 10.1186/Ar3515  0.43
2011 McNulty AL, Miller MR, O'Connor SK, Guilak F. The effects of adipokines on cartilage and meniscus catabolism. Connective Tissue Research. 52: 523-33. PMID 21787135 DOI: 10.3109/03008207.2011.597902  0.43
2011 Backus JD, Furman BD, Swimmer T, Kent CL, McNulty AL, Defrate LE, Guilak F, Olson SA. Cartilage viability and catabolism in the intact porcine knee following transarticular impact loading with and without articular fracture. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 29: 501-10. PMID 21337389 DOI: 10.1002/Jor.21270  0.353
2010 McNulty AL, Estes BT, Wilusz RE, Weinberg JB, Guilak F. Dynamic loading enhances integrative meniscal repair in the presence of interleukin-1. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 18: 830-8. PMID 20202487 DOI: 10.1016/J.Joca.2010.02.009  0.421
2009 McNulty AL, Weinberg JB, Guilak F. Inhibition of matrix metalloproteinases enhances in vitro repair of the meniscus. Clinical Orthopaedics and Related Research. 467: 1557-67. PMID 18975039 DOI: 10.1007/S11999-008-0596-6  0.429
2008 McNulty AL, Guilak F. Integrative repair of the meniscus: lessons from in vitro studies. Biorheology. 45: 487-500. PMID 18836248 DOI: 10.3233/Bir-2008-0489  0.427
2008 Wilusz RE, Weinberg JB, Guilak F, McNulty AL. Inhibition of integrative repair of the meniscus following acute exposure to interleukin-1 in vitro. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 26: 504-12. PMID 18050309 DOI: 10.1002/Jor.20538  0.42
2008 McNulty A, Weinberg JB, Guilak F. A24 Inhibition Of Matrix Metalloproteinases Enhances In Vitro Repair Of The Meniscus Osteoarthritis and Cartilage. 16. DOI: 10.1016/S1063-4584(08)60070-9  0.315
2007 McNulty AL, Moutos FT, Weinberg JB, Guilak F. Enhanced integrative repair of the porcine meniscus in vitro by inhibition of interleukin-1 or tumor necrosis factor alpha. Arthritis and Rheumatism. 56: 3033-42. PMID 17729298 DOI: 10.1002/Art.22839  0.393
2007 McNulty AL, Moutos FT, Weinberg JB, Guilak F. Strategies to Enhance Repair of the Meniscus Medicine & Science in Sports & Exercise. 39: 44. DOI: 10.1249/01.Mss.0000272380.27893.C0  0.323
2005 McNulty AL, Stabler TV, Vail TP, McDaniel GE, Kraus VB. Dehydroascorbate transport in human chondrocytes is regulated by hypoxia and is a physiologically relevant source of ascorbic acid in the joint. Arthritis and Rheumatism. 52: 2676-85. PMID 16142743 DOI: 10.1002/Art.21254  0.469
2005 McNulty AL, Vail TP, Kraus VB. Chondrocyte transport and concentration of ascorbic acid is mediated by SVCT2. Biochimica Et Biophysica Acta. 1712: 212-21. PMID 15921655 DOI: 10.1016/J.Bbamem.2005.04.009  0.462
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