Year |
Citation |
Score |
2016 |
Loyd C, Magrisso IJ, Haas M, Balusu S, Krishna R, Itoh N, Sandoval DA, Perez-Tilve D, Obici S, Habegger KM. Fibroblast growth factor 21 is required for beneficial effects of exercise during chronic high-fat feeding. Journal of Applied Physiology (Bethesda, Md. : 1985). jap.00456.2016. PMID 27445299 DOI: 10.1152/Japplphysiol.00456.2016 |
0.348 |
|
2016 |
Obici S. The Hypothalamic Melanocortin Pathway and the Regulation of Glucose Handling in the Kidney: A Sympathetic Look at Brain-Kidney Connection. Diabetes. 65: 548-50. PMID 26908905 DOI: 10.2337/Dbi15-0033 |
0.48 |
|
2015 |
Obici S, Magrisso IJ, Ghazarian AS, Shirazian A, Miller JR, Loyd CM, Begg DP, Krawczewski Carhuatanta KA, Haas MK, Davis JF, Woods SC, Sandoval DA, Seeley RJ, Goodyear LJ, Pothos EN, et al. Moderate voluntary exercise attenuates the metabolic syndrome in melanocortin-4 receptor-deficient rats showing central dopaminergic dysregulation. Molecular Metabolism. 4: 692-705. PMID 26500841 DOI: 10.1016/J.Molmet.2015.07.003 |
0.344 |
|
2015 |
Shen L, Haas M, Wang DQ, May A, Lo CC, Obici S, Tso P, Woods SC, Liu M. Ginsenoside Rb1 increases insulin sensitivity by activating AMP-activated protein kinase in male rats. Physiological Reports. 3. PMID 26359241 DOI: 10.14814/Phy2.12543 |
0.565 |
|
2014 |
Loyd C, Obici S. Brown fat fuel use and regulation of energy homeostasis. Current Opinion in Clinical Nutrition and Metabolic Care. 17: 368-72. PMID 24839950 DOI: 10.1097/Mco.0000000000000063 |
0.49 |
|
2014 |
Li X, Xu M, Wang F, Kohan AB, Haas MK, Yang Q, Lou D, Obici S, Davidson WS, Tso P. Apolipoprotein A-IV reduces hepatic gluconeogenesis through nuclear receptor NR1D1. The Journal of Biological Chemistry. 289: 2396-404. PMID 24311788 DOI: 10.1074/Jbc.M113.511766 |
0.473 |
|
2013 |
Habegger KM, Kirchner H, Yi CX, Heppner KM, Sweeney D, Ottaway N, Holland J, Amburgy S, Raver C, Krishna R, Müller TD, Perez-Tilve D, Pfluger PT, Obici S, DiMarchi RD, et al. GLP-1R agonism enhances adjustable gastric banding in diet-induced obese rats. Diabetes. 62: 3261-7. PMID 23775764 DOI: 10.2337/Db13-0117 |
0.317 |
|
2012 |
Wang F, Kohan AB, Kindel TL, Corbin KL, Nunemaker CS, Obici S, Woods SC, Davidson WS, Tso P. Apolipoprotein A-IV improves glucose homeostasis by enhancing insulin secretion. Proceedings of the National Academy of Sciences of the United States of America. 109: 9641-6. PMID 22619326 DOI: 10.1073/Pnas.1201433109 |
0.582 |
|
2011 |
Bajzer M, Olivieri M, Haas MK, Pfluger PT, Magrisso IJ, Foster MT, Tschöp MH, Krawczewski-Carhuatanta KA, Cota D, Obici S. Cannabinoid receptor 1 (CB1) antagonism enhances glucose utilisation and activates brown adipose tissue in diet-induced obese mice. Diabetologia. 54: 3121-31. PMID 21987346 DOI: 10.1007/S00125-011-2302-6 |
0.707 |
|
2011 |
Quarta C, Mazza R, Obici S, Pasquali R, Pagotto U. Energy balance regulation by endocannabinoids at central and peripheral levels. Trends in Molecular Medicine. 17: 518-26. PMID 21816675 DOI: 10.1016/J.Molmed.2011.05.002 |
0.41 |
|
2011 |
Hsuchou H, Kastin AJ, Tu H, Markadakis EN, Stone KP, Wang Y, Heymsfield SB, Chua SS, Obici S, Magrisso IJ, Pan W. Effects of cell-type specific leptin receptor mutation on leptin transport across the BBB. Peptides. 32: 1392-9. PMID 21616110 DOI: 10.1016/J.Peptides.2011.05.011 |
0.366 |
|
2011 |
Lo CM, Obici S, Dong HH, Haas M, Lou D, Kim DH, Liu M, D'Alessio D, Woods SC, Tso P. Impaired insulin secretion and enhanced insulin sensitivity in cholecystokinin-deficient mice. Diabetes. 60: 2000-7. PMID 21602512 DOI: 10.2337/Db10-0789 |
0.579 |
|
2011 |
Krawczewski Carhuatanta KA, Demuro G, Tschöp MH, Pfluger PT, Benoit SC, Obici S. Voluntary exercise improves high-fat diet-induced leptin resistance independent of adiposity. Endocrinology. 152: 2655-64. PMID 21586558 DOI: 10.1210/En.2010-1340 |
0.432 |
|
2011 |
Kindel TL, Martins PJ, Yoder SM, Jandacek RJ, Seeley RJ, D'Alessio DA, Obici S, Tso P. Bypassing the duodenum does not improve insulin resistance associated with diet-induced obesity in rodents. Obesity (Silver Spring, Md.). 19: 380-7. PMID 21030948 DOI: 10.1038/oby.2010.263 |
0.57 |
|
2010 |
Ayala JE, Samuel VT, Morton GJ, Obici S, Croniger CM, Shulman GI, Wasserman DH, McGuinness OP. Standard operating procedures for describing and performing metabolic tests of glucose homeostasis in mice. Disease Models & Mechanisms. 3: 525-34. PMID 20713647 DOI: 10.1242/Dmm.006239 |
0.435 |
|
2010 |
Martins PJ, Haas M, Obici S. Central nervous system delivery of the antipsychotic olanzapine induces hepatic insulin resistance. Diabetes. 59: 2418-25. PMID 20682682 DOI: 10.2337/Db10-0449 |
0.511 |
|
2010 |
Bajzer M, Haas M, Obici S. Effects of fasting/refeeding on brown adipose tissue thermogenesis in lean and obese mice Appetite. 54: 633. DOI: 10.1016/J.Appet.2010.04.018 |
0.658 |
|
2009 |
Sandoval DA, Obici S, Seeley RJ. Targeting the CNS to treat type 2 diabetes. Nature Reviews. Drug Discovery. 8: 386-98. PMID 19404312 DOI: 10.1038/Nrd2874 |
0.5 |
|
2009 |
Obici S. Minireview: Molecular targets for obesity therapy in the brain. Endocrinology. 150: 2512-7. PMID 19372196 DOI: 10.1210/En.2009-0409 |
0.416 |
|
2009 |
Cota D, Sandoval DA, Olivieri M, Prodi E, D'Alessio DA, Woods SC, Seeley RJ, Obici S. Food intake-independent effects of CB1 antagonism on glucose and lipid metabolism. Obesity (Silver Spring, Md.). 17: 1641-5. PMID 19325539 DOI: 10.1038/Oby.2009.84 |
0.592 |
|
2007 |
Lee M, Kim A, Chua SC, Obici S, Wardlaw SL. Transgenic MSH overexpression attenuates the metabolic effects of a high-fat diet. American Journal of Physiology. Endocrinology and Metabolism. 293: E121-31. PMID 17374695 DOI: 10.1152/Ajpendo.00555.2006 |
0.52 |
|
2006 |
Prodi E, Demuro G, Obici S. How the hypothalamus controls glucose production: an update. Expert Review of Endocrinology & Metabolism. 1: 601-608. PMID 30754102 DOI: 10.1586/17446651.1.5.601 |
0.539 |
|
2006 |
Demuro G, Obici S. Central nervous system and control of endogenous glucose production. Current Diabetes Reports. 6: 188-93. PMID 16898570 DOI: 10.1007/S11892-006-0033-8 |
0.552 |
|
2006 |
Prodi E, Obici S. Minireview: the brain as a molecular target for diabetic therapy. Endocrinology. 147: 2664-9. PMID 16556761 DOI: 10.1210/En.2006-0143 |
0.467 |
|
2006 |
Pocai A, Lam TK, Obici S, Gutierrez-Juarez R, Muse ED, Arduini A, Rossetti L. Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats. The Journal of Clinical Investigation. 116: 1081-91. PMID 16528412 DOI: 10.1172/Jci26640 |
0.415 |
|
2006 |
Du X, Edelstein D, Obici S, Higham N, Zou MH, Brownlee M. Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation. The Journal of Clinical Investigation. 116: 1071-80. PMID 16528409 DOI: 10.1172/Jci23354 |
0.507 |
|
2006 |
He W, Lam TK, Obici S, Rossetti L. Molecular disruption of hypothalamic nutrient sensing induces obesity. Nature Neuroscience. 9: 227-33. PMID 16415870 DOI: 10.1038/Nn1626 |
0.476 |
|
2005 |
Pocai A, Morgan K, Buettner C, Gutierrez-Juarez R, Obici S, Rossetti L. Central leptin acutely reverses diet-induced hepatic insulin resistance. Diabetes. 54: 3182-9. PMID 16249443 DOI: 10.2337/Diabetes.54.11.3182 |
0.575 |
|
2005 |
Pocai A, Obici S, Schwartz GJ, Rossetti L. A brain-liver circuit regulates glucose homeostasis. Cell Metabolism. 1: 53-61. PMID 16054044 DOI: 10.1016/J.Cmet.2004.11.001 |
0.388 |
|
2005 |
Okamoto H, Obici S, Accili D, Rossetti L. Restoration of liver insulin signaling in Insr knockout mice fails to normalize hepatic insulin action. The Journal of Clinical Investigation. 115: 1314-22. PMID 15864351 DOI: 10.1172/Jci23096 |
0.537 |
|
2005 |
Buettner C, Patel R, Muse ED, Bhanot S, Monia BP, McKay R, Obici S, Rossetti L. Severe impairment in liver insulin signaling fails to alter hepatic insulin action in conscious mice. The Journal of Clinical Investigation. 115: 1306-13. PMID 15864350 DOI: 10.1172/Jci23109 |
0.538 |
|
2005 |
Pocai A, Lam TK, Gutierrez-Juarez R, Obici S, Schwartz GJ, Bryan J, Aguilar-Bryan L, Rossetti L. Hypothalamic K(ATP) channels control hepatic glucose production. Nature. 434: 1026-31. PMID 15846348 DOI: 10.1038/Nature03439 |
0.493 |
|
2005 |
Lam TK, Pocai A, Gutierrez-Juarez R, Obici S, Bryan J, Aguilar-Bryan L, Schwartz GJ, Rossetti L. Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis. Nature Medicine. 11: 320-7. PMID 15735652 DOI: 10.1038/Nm1201 |
0.435 |
|
2004 |
Gutiérrez-Juárez R, Obici S, Rossetti L. Melanocortin-independent effects of leptin on hepatic glucose fluxes. The Journal of Biological Chemistry. 279: 49704-15. PMID 15364916 DOI: 10.1074/Jbc.M408665200 |
0.502 |
|
2004 |
Muse ED, Obici S, Bhanot S, Monia BP, McKay RA, Rajala MW, Scherer PE, Rossetti L. Role of resistin in diet-induced hepatic insulin resistance. The Journal of Clinical Investigation. 114: 232-9. PMID 15254590 DOI: 10.1172/Jci21270 |
0.538 |
|
2004 |
Rangwala SM, Rich AS, Rhoades B, Shapiro JS, Obici S, Rossetti L, Lazar MA. Abnormal glucose homeostasis due to chronic hyperresistinemia. Diabetes. 53: 1937-41. PMID 15189975 DOI: 10.2337/Diabetes.53.8.1937 |
0.553 |
|
2004 |
Morgan K, Obici S, Rossetti L. Hypothalamic responses to long-chain fatty acids are nutritionally regulated. The Journal of Biological Chemistry. 279: 31139-48. PMID 15155754 DOI: 10.1074/Jbc.M400458200 |
0.389 |
|
2004 |
Banerjee RR, Rangwala SM, Shapiro JS, Rich AS, Rhoades B, Qi Y, Wang J, Rajala MW, Pocai A, Scherer PE, Steppan CM, Ahima RS, Obici S, Rossetti L, Lazar MA. Regulation of fasted blood glucose by resistin. Science (New York, N.Y.). 303: 1195-8. PMID 14976316 DOI: 10.1126/Science.1092341 |
0.56 |
|
2004 |
Combs TP, Pajvani UB, Berg AH, Lin Y, Jelicks LA, Laplante M, Nawrocki AR, Rajala MW, Parlow AF, Cheeseboro L, Ding YY, Russell RG, Lindemann D, Hartley A, Baker GR, ... Obici S, et al. A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity. Endocrinology. 145: 367-83. PMID 14576179 DOI: 10.1210/En.2003-1068 |
0.542 |
|
2003 |
Obici S, Rossetti L. Minireview: nutrient sensing and the regulation of insulin action and energy balance. Endocrinology. 144: 5172-8. PMID 12970158 DOI: 10.1210/En.2003-0999 |
0.429 |
|
2003 |
Obici S, Feng Z, Arduini A, Conti R, Rossetti L. Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production. Nature Medicine. 9: 756-61. PMID 12754501 DOI: 10.1038/Nm873 |
0.39 |
|
2003 |
Gelling RW, Du XQ, Dichmann DS, Romer J, Huang H, Cui L, Obici S, Tang B, Holst JJ, Fledelius C, Johansen PB, Rossetti L, Jelicks LA, Serup P, Nishimura E, et al. Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 1438-43. PMID 12552113 DOI: 10.1073/Pnas.0237106100 |
0.532 |
|
2003 |
Rajala MW, Obici S, Scherer PE, Rossetti L. Adipose-derived resistin and gut-derived resistin-like molecule-beta selectively impair insulin action on glucose production. The Journal of Clinical Investigation. 111: 225-30. PMID 12531878 DOI: 10.1172/Jci16521 |
0.576 |
|
2002 |
Obici S, Zhang BB, Karkanias G, Rossetti L. Hypothalamic insulin signaling is required for inhibition of glucose production. Nature Medicine. 8: 1376-82. PMID 12426561 DOI: 10.1038/Nm1202-798 |
0.535 |
|
2002 |
Obici S, Wang J, Chowdury R, Feng Z, Siddhanta U, Morgan K, Rossetti L. Identification of a biochemical link between energy intake and energy expenditure. The Journal of Clinical Investigation. 109: 1599-605. PMID 12070307 DOI: 10.1172/Jci15258 |
0.324 |
|
2002 |
Obici S, Feng Z, Karkanias G, Baskin DG, Rossetti L. Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats. Nature Neuroscience. 5: 566-72. PMID 12021765 DOI: 10.1038/Nn0602-861 |
0.503 |
|
2002 |
Obici S, Feng Z, Morgan K, Stein D, Karkanias G, Rossetti L. Central administration of oleic acid inhibits glucose production and food intake. Diabetes. 51: 271-5. PMID 11812732 DOI: 10.2337/Diabetes.51.2.271 |
0.361 |
|
2001 |
Combs TP, Berg AH, Obici S, Scherer PE, Rossetti L. Endogenous glucose production is inhibited by the adipose-derived protein Acrp30. The Journal of Clinical Investigation. 108: 1875-81. PMID 11748271 DOI: 10.1172/Jci14120 |
0.527 |
|
2001 |
Wang J, Obici S, Morgan K, Barzilai N, Feng Z, Rossetti L. Overfeeding rapidly induces leptin and insulin resistance. Diabetes. 50: 2786-91. PMID 11723062 DOI: 10.2337/Diabetes.50.12.2786 |
0.538 |
|
2001 |
Obici S, Feng Z, Tan J, Liu L, Karkanias G, Rossetti L. Central melanocortin receptors regulate insulin action. The Journal of Clinical Investigation. 108: 1079-85. PMID 11581309 DOI: 10.1172/Jci12954 |
0.511 |
|
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