Hanne Ostergaard - Publications

Affiliations: 
University of Alberta, Edmonton, Alberta, Canada 
Area:
Immunology, Microbiology Biology

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bonaud A, Clare S, Bisio V, Sowerby JM, Yao S, Ostergaard H, Balabanian K, Smith KGC, Espéli M. Leupaxin Expression Is Dispensable for B Cell Immune Responses. Frontiers in Immunology. 11: 466. PMID 32269569 DOI: 10.3389/Fimmu.2020.00466  0.347
2016 Cheung SM, Ostergaard HL. Pyk2 Controls Integrin-Dependent CTL Migration through Regulation of De-Adhesion. Journal of Immunology (Baltimore, Md. : 1950). PMID 27456486 DOI: 10.4049/jimmunol.1501505  0.446
2013 St-Pierre J, Ostergaard HL. A role for the protein tyrosine phosphatase CD45 in macrophage adhesion through the regulation of paxillin degradation. Plos One. 8: e71531. PMID 23936270 DOI: 10.1371/journal.pone.0071531  0.723
2011 Robertson LK, Ostergaard HL. Paxillin associates with the microtubule cytoskeleton and the immunological synapse of CTL through its leucine-aspartic acid domains and contributes to microtubule organizing center reorientation. Journal of Immunology (Baltimore, Md. : 1950). 187: 5824-33. PMID 22043013 DOI: 10.4049/jimmunol.1003690  0.467
2011 St-Pierre J, Lysechko TL, Ostergaard HL. Hypophosphorylated and inactive Pyk2 associates with paxillin at the microtubule organizing center in hematopoietic cells. Cellular Signalling. 23: 718-30. PMID 21195757 DOI: 10.1016/j.cellsig.2010.12.006  0.553
2010 Lysechko TL, Cheung SM, Ostergaard HL. Regulation of the tyrosine kinase Pyk2 by calcium is through production of reactive oxygen species in cytotoxic T lymphocytes. The Journal of Biological Chemistry. 285: 31174-84. PMID 20688918 DOI: 10.1074/jbc.M110.118265  0.38
2010 Ferguson BV, Ostergaard HL. CD45 regulates thymocyte survival during development in fetal thymic organ culture. Immunobiology. 215: 458-65. PMID 19765855 DOI: 10.1016/j.imbio.2009.08.005  0.456
2007 Ostergaard HL. PKC and Erk in CTL degranulation Modern Aspects of Immunobiology. 21: 7.  0.392
2006 Puente LG, He JS, Ostergaard HL. A novel PKC regulates ERK activation and degranulation of cytotoxic T lymphocytes: Plasticity in PKC regulation of ERK. European Journal of Immunology. 36: 1009-18. PMID 16552708 DOI: 10.1002/Eji.200535277  0.768
2005 Robertson LK, Mireau LR, Ostergaard HL. A role for phosphatidylinositol 3-kinase in TCR-stimulated ERK activation leading to paxillin phosphorylation and CTL degranulation. Journal of Immunology (Baltimore, Md. : 1950). 175: 8138-45. PMID 16339552  0.485
2005 Shen A, Puente LG, Ostergaard HL. Tyrosine kinase activity and remodelling of the actin cytoskeleton are co-temporally required for degranulation by cytotoxic T lymphocytes. Immunology. 116: 276-86. PMID 16162276 DOI: 10.1111/J.1365-2567.2005.02222.X  0.744
2005 Lysechko TL, Ostergaard HL. Differential Src family kinase activity requirements for CD3 zeta phosphorylation/ZAP70 recruitment and CD3 epsilon phosphorylation. Journal of Immunology (Baltimore, Md. : 1950). 174: 7807-14. PMID 15944285 DOI: 10.4049/jimmunol.174.12.7807  0.626
2005 Ostergaard HL, Lysechko TL. Focal adhesion kinase-related protein tyrosine kinase Pyk2 in T-cell activation and function. Immunologic Research. 31: 267-82. PMID 15888917 DOI: 10.1385/IR:31:3:267  0.474
2005 Puente LG, Mireau LR, Lysechko TL, Ostergaard HL. Phosphatidylinositol-3-kinase regulates PKCtheta activity in cytotoxic T cells. Molecular Immunology. 42: 1177-84. PMID 15829307 DOI: 10.1016/J.Molimm.2004.11.012  0.792
2005 Chun J, Chau AS, Maingat FG, Edmonds SD, Ostergaard HL, Shibuya EK. Phosphorylation of Cdc25C by pp90Rsk contributes to a G2 cell cycle arrest in Xenopus cycling egg extracts. Cell Cycle (Georgetown, Tex.). 4: 148-54. PMID 15539959  0.345
2003 Puente LG, Ostergaard HL. Beta 1/beta 3 integrin ligation is uncoupled from ERK1/ERK2 activation in cytotoxic T lymphocytes. Journal of Leukocyte Biology. 73: 391-8. PMID 12629153 DOI: 10.1189/Jlb.0402199  0.743
2002 Edmonds SD, Ostergaard HL. Dynamic association of CD45 with detergent-insoluble microdomains in T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 169: 5036-42. PMID 12391219  0.534
2002 Baldwin TA, Ostergaard HL. The protein-tyrosine phosphatase CD45 reaches the cell surface via golgi-dependent and -independent pathways. The Journal of Biological Chemistry. 277: 50333-40. PMID 12386161 DOI: 10.1074/Jbc.M209075200  0.728
2002 Wang C, Hayashi H, Harrison R, Chiu B, Chan JR, Ostergaard HL, Inman RD, Jongstra J, Cybulsky MI, Jongstra-Bilen J. Modulation of Mac-1 (CD11b/CD18)-mediated adhesion by the leukocyte-specific protein 1 is key to its role in neutrophil polarization and chemotaxis. Journal of Immunology (Baltimore, Md. : 1950). 169: 415-23. PMID 12077272 DOI: 10.4049/Jimmunol.169.1.415  0.304
2001 Baldwin TA, Ostergaard HL. Developmentally regulated changes in glucosidase II association with, and carbohydrate content of, the protein tyrosine phosphatase CD45. Journal of Immunology (Baltimore, Md. : 1950). 167: 3829-35. PMID 11564800 DOI: 10.4049/Jimmunol.167.7.3829  0.731
2000 Puente LG, Stone JC, Ostergaard HL. Evidence for protein kinase C-dependent and -independent activation of mitogen-activated protein kinase in T cells: potential role of additional diacylglycerol binding proteins. Journal of Immunology (Baltimore, Md. : 1950). 165: 6865-71. PMID 11120810 DOI: 10.4049/Jimmunol.165.12.6865  0.791
2000 Dower NA, Stang SL, Bottorff DA, Ebinu JO, Dickie P, Ostergaard HL, Stone JC. RasGRP is essential for mouse thymocyte differentiation and TCR signaling Nature Immunology. 1: 317-321. PMID 11017103  0.437
2000 Baldwin TA, Gogela-Spehar M, Ostergaard HL. Specific isoforms of the resident endoplasmic reticulum protein glucosidase II associate with the CD45 protein-tyrosine phosphatase via a lectin-like interaction. The Journal of Biological Chemistry. 275: 32071-6. PMID 10921916 DOI: 10.1074/Jbc.M003088200  0.724
2000 Ebinu JO, Stang SL, Teixeira C, Bottorff DA, Hooton J, Blumberg PM, Barry M, Bleakley RC, Ostergaard HL, Stone JC. RasGRP links T-cell receptor signaling to Ras Blood. 95: 3199-3203. DOI: 10.1182/blood.v95.10.3199.010k37_3199_3203  0.396
2000 Ebinu JO, Stang SL, Teixeira C, Bottorff DA, Hooton J, Blumberg PM, Barry M, Bleakley RC, Ostergaard HL, Stone JC. RasGRP links T-cell receptor signaling to Ras Blood. 95: 3199-3203. DOI: 10.1182/Blood.V95.10.3199  0.396
2000 Edmonds SD, Ostergaard HL. ASSOCIATION OF THE PROTEIN TYROSINE PHOSPHATASE CD45 WITH THE PROTEIN TYROSINE KINASE LCK AND THE ADAPTER PROTEIN LAT Biochemical Society Transactions. 28: A428-A428. DOI: 10.1042/bst028a428b  0.421
1998 Berg NN, Puente LG, Dawicki W, Ostergaard HL. Sustained TCR signaling is required for mitogen-activated protein kinase activation and degranulation by cytotoxic T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 161: 2919-24. PMID 9743353  0.776
1998 Ostergaard HL, Lou O, Arendt CW, Berg NN. Paxillin phosphorylation and association with Lck and Pyk2 in anti-CD3- or anti-CD45-stimulated T cells. The Journal of Biological Chemistry. 273: 5692-6. PMID 9488700 DOI: 10.1074/jbc.273.10.5692  0.612
1997 Berg NN, Ostergaard HL. T Cell Receptor Engagement Induces Tyrosine Phosphorylation of FAK and Pyk2 and their Association with Lck Journal of Immunology. 159: 1753-1757. PMID 9257837  0.514
1997 Arendt CW, Ostergaard HL. Identification of the CD45-associated 116-kDa and 80-kDa proteins as the alpha- and beta-subunits of alpha-glucosidase II. The Journal of Biological Chemistry. 272: 13117-25. PMID 9148925 DOI: 10.1074/jbc.272.20.13117  0.359
1997 Ma EA, Lou O, Berg NN, Ostergaard HL. Cytotoxic T lymphocytes express a β3 integrin which can induce the phosphorylation of focal adhesion kinase and the related PYK-2 European Journal of Immunology. 27: 329-335. PMID 9022036 DOI: 10.1002/eji.1830270147  0.458
1996 Atkinson EA, Ostergaard H, Kane K, Pinkoski MJ, Caputo A, Olszowy MW, Bleackley RC. A physical interaction between the cell death protein Fas and the tyrosine kinase p59fynT. The Journal of Biological Chemistry. 271: 5968-71. PMID 8626376  0.476
1995 Ostergaard HL, Ma EA. Fibronectin induces phosphorylation of a 120-kDa protein and synergizes with the T cell receptor to activate cytotoxic T cell clones European Journal of Immunology. 25: 252-256. PMID 7843239 DOI: 10.1002/eji.1830250141  0.621
1995 Arendt CW, Ostergaard HL. CD45 protein-tyrosine phosphatase is specifically associated with a 116-kDa tyrosine-phosphorylated glycoprotein. The Journal of Biological Chemistry. 270: 2313-9. PMID 7836464  0.463
1995 Mossman K, Ostergaard H, Upton C, McFadden G. Myxoma virus and shope fibroma virus encode dual-specificity tyrosine/serine phosphatases which are essential for virus viability Virology. 206: 572-582. PMID 7831813 DOI: 10.1016/S0042-6822(95)80074-3  0.302
1995 Berg NN, Ostergaard HL. Characterization of intercellular adhesion molecule-1 (ICAM-1)-augmented degranulation by cytotoxic T cells ICAM-1 and anti-CD3 must be co-localized for optimal adhesion and stimulation Journal of Immunology. 155: 1694-1702. PMID 7636228  0.484
1995 Arendt CW, Hsi G, Ostergaard HL. Immobilized antibodies to CD45 induce rapid morphologic changes and increased tyrosine phosphorylation of p56lck-associated proteins in T cells. Journal of Immunology (Baltimore, Md. : 1950). 155: 5095-103. PMID 7594518  0.603
1992 Trowbridge IS, Johnson P, Ostergaard H, Hole N. Structure and function of CD45: A leukocyte-specific protein tyrosine phosphatase Advances in Experimental Medicine and Biology. 323: 29-38. PMID 1485564 DOI: 10.1007/978-1-4615-3396-2_5  0.564
1992 Trowbridge IS, Johnson P, Ostergaard H, Hole N. Regulation and structure-function relationship of CD45 Biochemical Society Transactions. 20: 174-178. PMID 1386037 DOI: 10.1042/Bst0200174  0.455
1992 Johnson P, Ostergaard HL, Wasden C, Trowbridge IS. Mutational analysis of CD45. A leukocyte-specific protein tyrosine phosphatase Journal of Biological Chemistry. 267: 8035-8041. PMID 1314815  0.344
1991 Taetle R, Ostergaard H, Smedsrud M, Trowbridge I. Regulation of CD45 expression in human leukemia cells Leukemia. 5: 309-314. PMID 1851241  0.505
1991 Ostergaard HL, Trowbridge IS. Negative regulation of CD45 protein tyrosine phosphatase activity by ionomycin in T cells Science. 253: 1423-1425. PMID 1654595 DOI: 10.1126/Science.1654595  0.582
1990 Ostergaard HL, Trowbridge IS. Coclustering CD45 with CD4 or CD8 alters the phosphorylation and kinase activity of p56lck Journal of Experimental Medicine. 172: 347-350. PMID 2141630 DOI: 10.1084/Jem.172.1.347  0.555
1989 Ostergaard HL, Shackelford DA, Hurley TR, Johnson P, Hyman R, Sefton BM, Trowbridge IS. Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines. Proceedings of the National Academy of Sciences of the United States of America. 86: 8959-63. PMID 2530588 DOI: 10.1073/Pnas.86.22.8959  0.569
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