| Year |
Citation |
Score |
| 2021 |
Stamatiades GA, Toufaily C, Kim HK, Zhou X, Thompson IR, Carroll RS, Chen M, Weinstein LS, Offermanns S, Boehm U, Bernard DJ, Kaiser UB. Deletion of Gαq/11 or Gαs proteins in gonadotropes differentially affects gonadotropin production and secretion in mice. Endocrinology. PMID 34864945 DOI: 10.1210/endocr/bqab247 |
0.34 |
|
| 2021 |
Leon S, Talbi R, McCarthy EA, Fergani C, Ferrari K, Naule L, Choi JH, Carroll RS, Kaiser UB, Aylwin CF, Lomniczi A, Navarro VM. Sex specific pubertal and metabolic regulation of Kiss1 neurons via Nhlh2. Elife. 10. PMID 34494548 DOI: 10.7554/eLife.69765 |
0.304 |
|
| 2021 |
Hausken KN, Noel SD, Kim HK, Carroll RS, Kaiser UB. Mutation of the GnRHR Proximal Promoter AP-1 Element in Mice Results in Suboptimal GnRH Induction of LH and an Abnormal Reproductive Phenotype Journal of the Endocrine Society. 5: A545-A546. DOI: 10.1210/jendso/bvab048.1111 |
0.327 |
|
| 2020 |
Maione L, Naulé L, Kaiser UB. Makorin RING finger protein 3 and central precocious puberty. Current Opinion in Endocrine and Metabolic Research. 14: 152-159. PMID 32984644 DOI: 10.1016/J.Coemr.2020.08.003 |
0.391 |
|
| 2020 |
Dichtel LE, Kimball A, Yuen KCJ, Woodmansee W, Haines MS, Guan QX, Swearingen B, Nachtigall LB, Tritos NA, Sharpless JL, Kaiser UB, Gerweck AV, Miller KK. Effects of Growth Hormone Receptor Antagonism and Somatostatin Analog Administration on Quality of Life in Acromegaly. Clinical Endocrinology. PMID 32779234 DOI: 10.1111/Cen.14309 |
0.303 |
|
| 2020 |
Roberts S, Kaiser UB. GENETICS IN ENDOCRINOLOGY: Genetic etiologies of central precocious puberty and the role of imprinted genes. European Journal of Endocrinology. PMID 32698138 DOI: 10.1530/Eje-20-0103 |
0.367 |
|
| 2020 |
Roberts SA, Abreu AP, Navarro VM, Liang JN, Maguire CA, Kim HK, Carroll RS, Kaiser UB. The Peripubertal Decline in Expression is Independent of Leptin Action. Journal of the Endocrine Society. 4: bvaa059. PMID 32587933 DOI: 10.1210/Jendso/Bvaa059 |
0.381 |
|
| 2020 |
Abreu AP, Toro CA, Song YB, Navarro VM, Bosch MA, Eren A, Liang JN, Carroll RS, Latronico AC, Ronnekleiv OK, Aylwin CF, Lomniczi A, Ojeda SR, Kaiser UB. MKRN3 inhibits the reproductive axis through actions in kisspeptin-expressing neurons. The Journal of Clinical Investigation. PMID 32407292 DOI: 10.1172/Jci136564 |
0.452 |
|
| 2020 |
Seraphim CE, Canton APM, Montenegro LR, Piovesan MR, Bohlen TM, Frazao R, Macedo DB, Faria AGd, Ramos C, Gagliardi PC, Abreu AP, Leal AdC, Castro MD, Antonini SRR, Soriano-Guillén L, ... ... Kaiser UB, et al. SUN-085 Clinical and Hormonal Features of 37 Families with Central Precocious Puberty Due to MKRN3 Loss-Of -Function Mutations Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1379 |
0.321 |
|
| 2019 |
Macedo DB, Kaiser UB. DLK1, Notch Signaling and the Timing of Puberty. Seminars in Reproductive Medicine. 37: 174-181. PMID 31972862 DOI: 10.1055/S-0039-3400963 |
0.368 |
|
| 2019 |
Naulé L, Kaiser UB. Evolutionary Conservation of MKRN3 and Other Makorins and Their Roles in Puberty Initiation and Endocrine Functions. Seminars in Reproductive Medicine. 37: 166-173. PMID 31972861 DOI: 10.1055/S-0039-3400965 |
0.366 |
|
| 2019 |
Clark EA, Wu F, Chen Y, Kang P, Kaiser UB, Fang R, Shi YG. GR and LSD1/KDM1A-Targeted Gene Activation Requires Selective H3K4me2 Demethylation at Enhancers. Cell Reports. 27: 3522-3532.e3. PMID 31216473 DOI: 10.1016/J.Celrep.2019.05.062 |
0.357 |
|
| 2019 |
Stamatiades GA, Carroll RS, Kaiser UB. GnRH-A Key Regulator of FSH. Endocrinology. 160: 57-67. PMID 30517625 DOI: 10.1210/En.2018-00889 |
0.461 |
|
| 2019 |
Abreu AP, Garcia L, Pereira S, Macedo D, Magnusson M, Gagliardi P, Tütüncüler F, Bird K, Lofrano-Porto A, Roberts S, Carroll R, Latronico AC, Kaiser U. SUN-264 Mutations in the Maternally Imprinted Genes, MKRN3 and DLK1, Associated with Central Precocious Puberty Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sun-264 |
0.311 |
|
| 2019 |
Masterson T, Bitran J, Molina M, Ibrahim E, Kaiser U, Ramasamy R. SUN-220 The Effect of Testosterone Nasal Gel on Reproductive Hormones and Semen Parameters Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sun-220 |
0.34 |
|
| 2018 |
Garrel G, Denoyelle C, L'Hôte D, Picard JY, Teixeira J, Kaiser UB, Laverrière JN, Cohen-Tannoudji J. GnRH transactivates human AMH receptor gene via Egr1 and FOXO1 in gonadotrope cells. Neuroendocrinology. PMID 30368511 DOI: 10.1159/000494890 |
0.44 |
|
| 2018 |
Ross RA, Leon S, Madara JC, Schafer D, Fergani C, Maguire CA, Verstegen AM, Brengle E, Kong D, Herbison AE, Kaiser UB, Lowell BB, Navarro VM. PACAP neurons in the ventral premammillary nucleus regulate reproductive function in the female mouse. Elife. 7. PMID 29905528 DOI: 10.7554/Elife.35960 |
0.366 |
|
| 2018 |
Macedo D, França MM, Montenegro L, Cunha-Silva M, Bessa DS, Abreu AP, Kaiser UB, Mendonca BB, Jorge AAL, Brito VN, Latronico AC. CENTRAL PRECOCIOUS PUBERTY CAUSED BY A HETEROZYGOUS DELETION IN THE MKRN3 PROMOTER REGION. Neuroendocrinology. PMID 29763903 DOI: 10.1159/000490059 |
0.313 |
|
| 2018 |
Ross RA, Leon S, Madara JC, Schafer D, Fergani C, Maguire CA, Verstegen AM, Brengle E, Kong D, Herbison AE, Kaiser UB, Lowell BB, Navarro VM. Author response: PACAP neurons in the ventral premammillary nucleus regulate reproductive function in the female mouse Elife. DOI: 10.7554/Elife.35960.014 |
0.321 |
|
| 2017 |
Stamatiades GA, Kaiser UB. Gonadotropin regulation by pulsatile GnRH: Signaling and gene expression. Molecular and Cellular Endocrinology. PMID 29102564 DOI: 10.1016/J.Mce.2017.10.015 |
0.471 |
|
| 2017 |
Maguire CA, Song YB, Wu M, León S, Carroll RS, Alreja M, Kaiser UB, Navarro VM. Tac1 Signaling is Required for Sexual Maturation and Responsiveness of GnRH Neurons to Kisspeptin in the Male Mouse. Endocrinology. PMID 28444173 DOI: 10.1210/En.2016-1807 |
0.416 |
|
| 2017 |
Zheng J, Mao J, Xu H, Wang X, Huang B, Liu Z, Cui M, Xiong S, Ma W, Min L, Kaiser UB, Nie M, Wu X. Pulsatile GnRH therapy may restore hypothalamus-pituitary-testis axis function in patients with congenital combined pituitary hormone deficiency: a prospective, self-controlled trial. The Journal of Clinical Endocrinology and Metabolism. PMID 28368486 DOI: 10.1210/Jc.2016-3990 |
0.399 |
|
| 2017 |
Dauber A, Cunha-Silva M, Macedo DB, Brito VN, Abreu AP, Roberts SA, Montenegro LR, Andrew M, Kirby A, Weirauch MT, Labilloy G, Bessa DS, Carroll RS, Jacobs DC, Chappell PE, ... ... Kaiser UB, et al. Paternally Inherited DLK1 Deletion Associated with Familial Central Precocious Puberty. The Journal of Clinical Endocrinology and Metabolism. PMID 28324015 DOI: 10.1210/Jc.2016-3677 |
0.392 |
|
| 2016 |
Mao JF, Liu ZX, Nie M, Wang X, Xu HL, Huang BK, Zheng JJ, Min L, Kaiser UB, Wu XY. Pulsatile gonadotropin-releasing hormone therapy is associated with earlier spermatogenesis compared to combined gonadotropin therapy in patients with congenital hypogonadotropic hypogonadism. Asian Journal of Andrology. PMID 28051040 DOI: 10.4103/1008-682X.193568 |
0.31 |
|
| 2016 |
Stecchini MF, Macedo DB, Reis AC, Abreu AP, Moreira AC, Castro M, Kaiser UB, Latronico AC, Antonini SR. Time Course of Central Precocious Puberty Development Caused by an MKRN3 Gene Mutation: A Prismatic Case. Hormone Research in Paediatrics. PMID 27424312 DOI: 10.1159/000447515 |
0.332 |
|
| 2016 |
Bessa DS, Macedo DB, Brito VN, França MM, Montenegro LR, Silva MC, Silveira LG, Hummel T, Bergadá I, Braslavsky D, Abreu AP, Dauber A, Mendonca BB, Kaiser UB, Latronico AC. High Frequency of MKRN3 Mutations in Male Central Precocious Puberty Previously Classified as Idiopathic. Neuroendocrinology. PMID 27225315 DOI: 10.1159/000446963 |
0.337 |
|
| 2016 |
Abreu AP, Kaiser UB. Pubertal development and regulation. The Lancet. Diabetes & Endocrinology. PMID 26852256 DOI: 10.1016/S2213-8587(15)00418-0 |
0.355 |
|
| 2016 |
Thompson IR, Ciccone NA, Zhou Q, Xu S, Khogeer A, Carroll RS, Kaiser UB. GnRH Pulse Frequency Control of Fshb Gene Expression is Mediated via ERK1/2 Regulation of ICER. Molecular Endocrinology (Baltimore, Md.). me20151222. PMID 26835742 DOI: 10.1210/Me.2015-1222 |
0.384 |
|
| 2015 |
Cote DJ, Smith TR, Sandler CN, Gupta T, Bale TA, Bi WL, Dunn IF, De Girolami U, Woodmansee WW, Kaiser UB, Laws ER. Functional Gonadotroph Adenomas: Case Series and Report of Literature. Neurosurgery. PMID 26692108 DOI: 10.1227/Neu.0000000000001188 |
0.357 |
|
| 2015 |
Min L, Leon S, Li H, Pinilla L, Carroll RS, Tena-Sempere M, Kaiser UB. RF9 acts as a KISS1R agonist in vivo and in vitro. Endocrinology. en20151635. PMID 26418326 DOI: 10.1210/En.2015-1635 |
0.409 |
|
| 2015 |
Babwah AV, Navarro VM, Ahow M, Pampillo M, Nash C, Fayazi M, Calder M, Elbert A, Urbanski HF, Wettschureck N, Offermanns S, Carroll RS, Bhattacharya M, Tobet SA, Kaiser UB. GnRH Neuron-Specific Ablation of Gαq/11 Results in Only Partial Inactivation of the Neuroendocrine-Reproductive Axis in Both Male and Female Mice: In Vivo Evidence for Kiss1r-Coupled Gαq/11-Independent GnRH Secretion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 12903-16. PMID 26377475 DOI: 10.1523/Jneurosci.0041-15.2015 |
0.351 |
|
| 2015 |
Min L, Nie M, Zhang A, Wen J, Noel SD, Lee V, Carroll RS, Kaiser UB. Computational Analysis of Missense Variants of G Protein-Coupled Receptors Involved in the Neuroendocrine Regulation of Reproduction. Neuroendocrinology. PMID 26088945 DOI: 10.1159/000435884 |
0.32 |
|
| 2015 |
Abreu AP, Macedo DB, Brito VN, Kaiser UB, Latronico AC. A new pathway in the control of the initiation of puberty: the MKRN3 gene. Journal of Molecular Endocrinology. 54: R131-9. PMID 25957321 DOI: 10.1530/Jme-14-0315 |
0.409 |
|
| 2015 |
Simavli S, Thompson IR, Maguire CA, Gill JC, Carroll RS, Wolfe A, Kaiser UB, Navarro VM. Substance p regulates puberty onset and fertility in the female mouse. Endocrinology. 156: 2313-22. PMID 25856429 DOI: 10.1210/En.2014-2012 |
0.636 |
|
| 2015 |
Navarro VM, Bosch MA, León S, Simavli S, True C, Pinilla L, Carroll RS, Seminara SB, Tena-Sempere M, Rønnekleiv OK, Kaiser UB. The integrated hypothalamic tachykinin-kisspeptin system as a central coordinator for reproduction. Endocrinology. 156: 627-37. PMID 25422875 DOI: 10.1210/En.2014-1651 |
0.424 |
|
| 2014 |
Ahow M, Min L, Pampillo M, Nash C, Wen J, Soltis K, Carroll RS, Glidewell-Kenney CA, Mellon PL, Bhattacharya M, Tobet SA, Kaiser UB, Babwah AV. KISS1R signals independently of Gαq/11 and triggers LH secretion via the β-arrestin pathway in the male mouse. Endocrinology. 155: 4433-46. PMID 25147978 DOI: 10.1210/En.2014-1304 |
0.362 |
|
| 2014 |
Beneduzzi D, Trarbach EB, Min L, Jorge AA, Garmes HM, Renk AC, Fichna M, Fichna P, Arantes KA, Costa EM, Zhang A, Adeola O, Wen J, Carroll RS, Mendonça BB, ... Kaiser UB, et al. Role of gonadotropin-releasing hormone receptor mutations in patients with a wide spectrum of pubertal delay. Fertility and Sterility. 102: 838-846.e2. PMID 25016926 DOI: 10.1016/J.Fertnstert.2014.05.044 |
0.338 |
|
| 2014 |
Martin C, Navarro VM, Simavli S, Vong L, Carroll RS, Lowell BB, Kaiser UB. Leptin-responsive GABAergic neurons regulate fertility through pathways that result in reduced kisspeptinergic tone. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 6047-56. PMID 24760864 DOI: 10.1523/Jneurosci.3003-13.2014 |
0.371 |
|
| 2014 |
Macedo DB, Abreu AP, Reis AC, Montenegro LR, Dauber A, Beneduzzi D, Cukier P, Silveira LF, Teles MG, Carroll RS, Junior GG, Filho GG, Gucev Z, Arnhold IJ, de Castro M, ... ... Kaiser UB, et al. Central precocious puberty that appears to be sporadic caused by paternally inherited mutations in the imprinted gene makorin ring finger 3. The Journal of Clinical Endocrinology and Metabolism. 99: E1097-103. PMID 24628548 DOI: 10.1210/Jc.2013-3126 |
0.334 |
|
| 2014 |
Noel SD, Abreu AP, Xu S, Muyide T, Gianetti E, Tusset C, Carroll J, Latronico AC, Seminara SB, Carroll RS, Kaiser UB. TACR3 mutations disrupt NK3R function through distinct mechanisms in GnRH-deficient patients. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 1924-37. PMID 24376026 DOI: 10.1096/Fj.13-240630 |
0.373 |
|
| 2014 |
Min L, Soltis K, Reis AC, Xu S, Kuohung W, Jain M, Carroll RS, Kaiser UB. Dynamic kisspeptin receptor trafficking modulates kisspeptin-mediated calcium signaling. Molecular Endocrinology (Baltimore, Md.). 28: 16-27. PMID 24295737 DOI: 10.1210/Me.2013-1165 |
0.301 |
|
| 2014 |
Thompson IR, Kaiser UB. GnRH pulse frequency-dependent differential regulation of LH and FSH gene expression. Molecular and Cellular Endocrinology. 385: 28-35. PMID 24056171 DOI: 10.1016/J.Mce.2013.09.012 |
0.474 |
|
| 2013 |
Magill JC, Ciccone NA, Kaiser UB. A mathematical model of pulse-coded hormone signal responses in pituitary gonadotroph cells. Mathematical Biosciences. 246: 38-46. PMID 24095971 DOI: 10.1016/J.Mbs.2013.09.006 |
0.414 |
|
| 2013 |
Navarro VM, Kaiser UB. Metabolic influences on neuroendocrine regulation of reproduction. Current Opinion in Endocrinology, Diabetes, and Obesity. 20: 335-41. PMID 23807606 DOI: 10.1097/Med.0B013E32836318Ce |
0.345 |
|
| 2013 |
Abreu AP, Dauber A, Macedo DB, Noel SD, Brito VN, Gill JC, Cukier P, Thompson IR, Navarro VM, Gagliardi PC, Rodrigues T, Kochi C, Longui CA, Beckers D, de Zegher F, ... ... Kaiser UB, et al. Central precocious puberty caused by mutations in the imprinted gene MKRN3. The New England Journal of Medicine. 368: 2467-75. PMID 23738509 DOI: 10.1056/Nejmoa1302160 |
0.641 |
|
| 2013 |
Bianco SD, Kaiser UB. Molecular biology of the kisspeptin receptor: signaling, function, and mutations. Advances in Experimental Medicine and Biology. 784: 133-58. PMID 23550005 DOI: 10.1007/978-1-4614-6199-9_7 |
0.352 |
|
| 2013 |
Thompson IR, Ciccone NA, Xu S, Zaytseva S, Carroll RS, Kaiser UB. GnRH pulse frequency-dependent stimulation of FSHβ transcription is mediated via activation of PKA and CREB. Molecular Endocrinology (Baltimore, Md.). 27: 606-18. PMID 23393127 DOI: 10.1210/Me.2012-1281 |
0.379 |
|
| 2012 |
Tusset C, Noel SD, Trarbach EB, Silveira LF, Jorge AA, Brito VN, Cukier P, Seminara SB, Mendonça BB, Kaiser UB, Latronico AC. Mutational analysis of TAC3 and TACR3 genes in patients with idiopathic central pubertal disorders. Arquivos Brasileiros De Endocrinologia E Metabologia. 56: 646-52. PMID 23329188 DOI: 10.1590/S0004-27302012000900008 |
0.329 |
|
| 2012 |
Xu Y, Xu C, Kato A, Tempel W, Abreu JG, Bian C, Hu Y, Hu D, Zhao B, Cerovina T, Diao J, Wu F, He HH, Cui Q, Clark E, ... ... Kaiser UB, et al. Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus eye and neural development. Cell. 151: 1200-13. PMID 23217707 DOI: 10.1016/J.Cell.2012.11.014 |
0.336 |
|
| 2012 |
Babwah AV, Pampillo M, Min L, Kaiser UB, Bhattacharya M. Single-cell analyses reveal that KISS1R-expressing cells undergo sustained kisspeptin-induced signaling that is dependent upon an influx of extracellular Ca2+. Endocrinology. 153: 5875-87. PMID 23070548 DOI: 10.1210/En.2012-1747 |
0.332 |
|
| 2012 |
Gill JC, Navarro VM, Kwong C, Noel SD, Martin C, Xu S, Clifton DK, Carroll RS, Steiner RA, Kaiser UB. Increased neurokinin B (Tac2) expression in the mouse arcuate nucleus is an early marker of pubertal onset with differential sensitivity to sex steroid-negative feedback than Kiss1. Endocrinology. 153: 4883-93. PMID 22893725 DOI: 10.1210/En.2012-1529 |
0.631 |
|
| 2012 |
Gianetti E, Hall JE, Au MG, Kaiser UB, Quinton R, Stewart JA, Metzger DL, Pitteloud N, Mericq V, Merino PM, Levitsky LL, Izatt L, Lang-Muritano M, Fujimoto VY, Dluhy RG, et al. When genetic load does not correlate with phenotypic spectrum: lessons from the GnRH receptor (GNRHR). The Journal of Clinical Endocrinology and Metabolism. 97: E1798-807. PMID 22745237 DOI: 10.1210/Jc.2012-1264 |
0.34 |
|
| 2012 |
Abreu AP, Noel SD, Xu S, Carroll RS, Latronico AC, Kaiser UB. Evidence of the importance of the first intracellular loop of prokineticin receptor 2 in receptor function. Molecular Endocrinology (Baltimore, Md.). 26: 1417-27. PMID 22745195 DOI: 10.1210/Me.2012-1102 |
0.378 |
|
| 2011 |
Chan YM, Broder-Fingert S, Paraschos S, Lapatto R, Au M, Hughes V, Bianco SD, Min L, Plummer L, Cerrato F, De Guillebon A, Wu IH, Wahab F, Dwyer A, Kirsch S, ... ... Kaiser UB, et al. GnRH-deficient phenotypes in humans and mice with heterozygous variants in KISS1/Kiss1. The Journal of Clinical Endocrinology and Metabolism. 96: E1771-81. PMID 21880801 DOI: 10.1097/Ogx.0B013E318268D4Cb |
0.361 |
|
| 2011 |
Noel SD, Kaiser UB. G protein-coupled receptors involved in GnRH regulation: molecular insights from human disease. Molecular and Cellular Endocrinology. 346: 91-101. PMID 21736917 DOI: 10.1016/J.Mce.2011.06.022 |
0.377 |
|
| 2011 |
Martin C, Balasubramanian R, Dwyer AA, Au MG, Sidis Y, Kaiser UB, Seminara SB, Pitteloud N, Zhou QY, Crowley WF. The role of the prokineticin 2 pathway in human reproduction: evidence from the study of human and murine gene mutations. Endocrine Reviews. 32: 225-46. PMID 21037178 DOI: 10.1210/Er.2010-0007 |
0.421 |
|
| 2010 |
Gill JC, Wang O, Kakar S, Martinelli E, Carroll RS, Kaiser UB. Reproductive hormone-dependent and -independent contributions to developmental changes in kisspeptin in GnRH-deficient hypogonadal mice. Plos One. 5: e11911. PMID 20689830 DOI: 10.1371/Journal.Pone.0011911 |
0.642 |
|
| 2010 |
Fang R, Barbera AJ, Xu Y, Rutenberg M, Leonor T, Bi Q, Lan F, Mei P, Yuan GC, Lian C, Peng J, Cheng D, Sui G, Kaiser UB, Shi Y, et al. Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation. Molecular Cell. 39: 222-33. PMID 20670891 DOI: 10.1016/J.Molcel.2010.07.008 |
0.302 |
|
| 2010 |
Balasubramanian R, Dwyer A, Seminara SB, Pitteloud N, Kaiser UB, Crowley WF. Human GnRH deficiency: a unique disease model to unravel the ontogeny of GnRH neurons. Neuroendocrinology. 92: 81-99. PMID 20606386 DOI: 10.1159/000314193 |
0.396 |
|
| 2010 |
Hamnvik OP, Laury AR, Laws ER, Kaiser UB. Lymphocytic hypophysitis with diabetes insipidus in a young man. Nature Reviews. Endocrinology. 6: 464-70. PMID 20585348 DOI: 10.1038/Nrendo.2010.104 |
0.327 |
|
| 2010 |
Abreu AP, Kaiser UB, Latronico AC. The role of prokineticins in the pathogenesis of hypogonadotropic hypogonadism. Neuroendocrinology. 91: 283-90. PMID 20502053 DOI: 10.1159/000308880 |
0.376 |
|
| 2010 |
Sykiotis GP, Pitteloud N, Seminara SB, Kaiser UB, Crowley WF. Deciphering genetic disease in the genomic era: the model of GnRH deficiency. Science Translational Medicine. 2: 32rv2. PMID 20484732 DOI: 10.1126/Scitranslmed.3000288 |
0.386 |
|
| 2010 |
Kuohung W, Burnett M, Mukhtyar D, Schuman E, Ni J, Crowley WF, Glicksman MA, Kaiser UB. A high-throughput small-molecule ligand screen targeted to agonists and antagonists of the G-protein-coupled receptor GPR54. Journal of Biomolecular Screening. 15: 508-17. PMID 20460252 DOI: 10.1177/1087057110369701 |
0.329 |
|
| 2010 |
Teles MG, Trarbach EB, Noel SD, Guerra-Junior G, Jorge A, Beneduzzi D, Bianco SD, Mukherjee A, Baptista MT, Costa EM, De Castro M, Mendonça BB, Kaiser UB, Latronico AC. A novel homozygous splice acceptor site mutation of KISS1R in two siblings with normosmic isolated hypogonadotropic hypogonadism. European Journal of Endocrinology / European Federation of Endocrine Societies. 163: 29-34. PMID 20371656 DOI: 10.1530/Eje-10-0012 |
0.33 |
|
| 2010 |
Gianetti E, Tusset C, Noel SD, Au MG, Dwyer AA, Hughes VA, Abreu AP, Carroll J, Trarbach E, Silveira LF, Costa EM, de Mendonça BB, de Castro M, Lofrano A, Hall JE, ... ... Kaiser UB, et al. TAC3/TACR3 mutations reveal preferential activation of gonadotropin-releasing hormone release by neurokinin B in neonatal life followed by reversal in adulthood. The Journal of Clinical Endocrinology and Metabolism. 95: 2857-67. PMID 20332248 DOI: 10.1210/Jc.2009-2320 |
0.381 |
|
| 2010 |
Silveira LG, Noel SD, Silveira-Neto AP, Abreu AP, Brito VN, Santos MG, Bianco SD, Kuohung W, Xu S, Gryngarten M, Escobar ME, Arnhold IJ, Mendonca BB, Kaiser UB, Latronico AC. Mutations of the KISS1 gene in disorders of puberty. The Journal of Clinical Endocrinology and Metabolism. 95: 2276-80. PMID 20237166 DOI: 10.1210/Jc.2009-2421 |
0.376 |
|
| 2010 |
Ciccone NA, Xu S, Lacza CT, Carroll RS, Kaiser UB. Frequency-dependent regulation of follicle-stimulating hormone beta by pulsatile gonadotropin-releasing hormone is mediated by functional antagonism of bZIP transcription factors. Molecular and Cellular Biology. 30: 1028-40. PMID 20008557 DOI: 10.1128/Mcb.00848-09 |
0.425 |
|
| 2010 |
Silveira LFG, Noel SD, Silveira-Neto AP, Abreu AP, Brito VN, Santos MA, Bianco SDC, Kuohung W, Xu S, Gryngarten M, Escobar ME, Arnhold IJP, Mendonca BB, Kaiser UB, Latronico AC. Mutations of the KISS1 Gene Associated with Central Precocious Puberty Endocrine Reviews. 151: 1971-1971. DOI: 10.1210/Edrv.31.2.9980 |
0.347 |
|
| 2009 |
Raivio T, Sidis Y, Plummer L, Chen H, Ma J, Mukherjee A, Jacobson-Dickman E, Quinton R, Van Vliet G, Lavoie H, Hughes VA, Dwyer A, Hayes FJ, Xu S, Sparks S, ... Kaiser UB, et al. Impaired fibroblast growth factor receptor 1 signaling as a cause of normosmic idiopathic hypogonadotropic hypogonadism. The Journal of Clinical Endocrinology and Metabolism. 94: 4380-90. PMID 19820032 DOI: 10.1210/Jc.2009-0179 |
0.306 |
|
| 2009 |
Bianco SD, Kaiser UB. The genetic and molecular basis of idiopathic hypogonadotropic hypogonadism. Nature Reviews. Endocrinology. 5: 569-76. PMID 19707180 DOI: 10.1038/Nrendo.2009.177 |
0.423 |
|
| 2009 |
Ciccone NA, Kaiser UB. The biology of gonadotroph regulation. Current Opinion in Endocrinology, Diabetes, and Obesity. 16: 321-7. PMID 19491666 DOI: 10.1097/Med.0B013E32832D88Fb |
0.444 |
|
| 2009 |
Jeong KH, Gill JC, Nosé V, Parlow AF, Carroll RS, Kaiser UB. Expression of a gonadotropin-releasing hormone receptor-simian virus 40 T-antigen transgene has sex-specific effects on the reproductive axis. Endocrinology. 150: 3383-91. PMID 19282386 DOI: 10.1210/En.2008-1362 |
0.641 |
|
| 2008 |
Ciccone NA, Lacza CT, Hou MY, Gregory SJ, Kam KY, Xu S, Kaiser UB. A composite element that binds basic helix loop helix and basic leucine zipper transcription factors is important for gonadotropin-releasing hormone regulation of the follicle-stimulating hormone beta gene. Molecular Endocrinology (Baltimore, Md.). 22: 1908-23. PMID 18550775 DOI: 10.1210/Me.2007-0455 |
0.406 |
|
| 2008 |
Gill JC, Wadas B, Chen P, Portillo W, Reyna A, Jorgensen E, Mani S, Schwarting GA, Moenter SM, Tobet S, Kaiser UB. The gonadotropin-releasing hormone (GnRH) neuronal population is normal in size and distribution in GnRH-deficient and GnRH receptor-mutant hypogonadal mice. Endocrinology. 149: 4596-604. PMID 18499748 DOI: 10.1210/En.2008-0403 |
0.612 |
|
| 2008 |
Kaiser UB. Genetic labeling: new approaches to creating a gonadotroph "ID". Endocrinology. 149: 2699-700. PMID 18493024 DOI: 10.1210/En.2008-0365 |
0.414 |
|
| 2008 |
Teles MG, Bianco SD, Brito VN, Trarbach EB, Kuohung W, Xu S, Seminara SB, Mendonca BB, Kaiser UB, Latronico AC. A GPR54-activating mutation in a patient with central precocious puberty. The New England Journal of Medicine. 358: 709-15. PMID 18272894 DOI: 10.1056/Nejmoa073443 |
0.431 |
|
| 2007 |
Cogliati T, Delgado-Romero P, Norwitz ER, Guduric-Fuchs J, Kaiser UB, Wray S, Kirsch IR. Pubertal impairment in Nhlh2 null mice is associated with hypothalamic and pituitary deficiencies. Molecular Endocrinology (Baltimore, Md.). 21: 3013-27. PMID 17717072 DOI: 10.1210/Me.2005-0337 |
0.407 |
|
| 2007 |
Bédécarrats GY, Kaiser UB. Mutations in the human gonadotropin-releasing hormone receptor: insights into receptor biology and function. Seminars in Reproductive Medicine. 25: 368-78. PMID 17710733 DOI: 10.1055/S-2007-984743 |
0.439 |
|
| 2007 |
Jeong KH, Bakowska JC, Song IO, Fu N, Breakefield XO, Kaiser UB. Improvement in reproductive parameters in hypogonadal female mice by regulated gene replacement therapy in the central nervous system. Gene Therapy. 14: 1092-101. PMID 17476303 DOI: 10.1038/sj.gt.3302957 |
0.351 |
|
| 2007 |
Chattopadhyay N, Jeong KH, Yano S, Huang S, Pang JL, Ren X, Terwilliger E, Kaiser UB, Vassilev PM, Pollak MR, Brown EM. Calcium receptor stimulates chemotaxis and secretion of MCP-1 in GnRH neurons in vitro: potential impact on reduced GnRH neuron population in CaR-null mice. American Journal of Physiology. Endocrinology and Metabolism. 292: E523-32. PMID 17003237 DOI: 10.1152/Ajpendo.00372.2005 |
0.403 |
|
| 2006 |
Kuohung W, Kaiser UB. GPR54 and KiSS-1: role in the regulation of puberty and reproduction. Reviews in Endocrine & Metabolic Disorders. 7: 257-63. PMID 17206526 DOI: 10.1007/S11154-006-9020-2 |
0.457 |
|
| 2006 |
Mazhawidza W, Winters SJ, Kaiser UB, Kakar SS. Identification of gene networks modulated by activin in LbetaT2 cells using DNA microarray analysis. Histology and Histopathology. 21: 167-78. PMID 16329041 |
0.33 |
|
| 2005 |
Kanasaki H, Bedecarrats GY, Kam KY, Xu S, Kaiser UB. Gonadotropin-releasing hormone pulse frequency-dependent activation of extracellular signal-regulated kinase pathways in perifused LbetaT2 cells. Endocrinology. 146: 5503-13. PMID 16141398 DOI: 10.1210/En.2004-1317 |
0.368 |
|
| 2005 |
Kaiser UB, Kuohung W. KiSS-1 and GPR54 as new players in gonadotropin regulation and puberty. Endocrine. 26: 277-84. PMID 16034182 DOI: 10.1385/Endo:26:3:277 |
0.483 |
|
| 2005 |
Pask AJ, Kanasaki H, Kaiser UB, Conn PM, Janovick JA, Stockton DW, Hess DL, Justice MJ, Behringer RR. A novel mouse model of hypogonadotrophic hypogonadism: N-ethyl-N-nitrosourea-induced gonadotropin-releasing hormone receptor gene mutation. Molecular Endocrinology (Baltimore, Md.). 19: 972-81. PMID 15625238 DOI: 10.1210/Me.2004-0192 |
0.425 |
|
| 2005 |
Kam KY, Jeong KH, Norwitz ER, Jorgensen EM, Kaiser UB. Oct-1 and nuclear factor Y bind to the SURG-1 element to direct basal and gonadotropin-releasing hormone (GnRH)-stimulated mouse GnRH receptor gene transcription. Molecular Endocrinology (Baltimore, Md.). 19: 148-62. PMID 15388790 DOI: 10.1210/Me.2004-0025 |
0.412 |
|
| 2005 |
Gregory SJ, Lacza CT, Detz AA, Xu S, Petrillo LA, Kaiser UB. Synergy between activin A and gonadotropin-releasing hormone in transcriptional activation of the rat follicle-stimulating hormone-beta gene. Molecular Endocrinology (Baltimore, Md.). 19: 237-54. PMID 15375186 DOI: 10.1210/Me.2003-0473 |
0.415 |
|
| 2004 |
Gregory SJ, Kaiser UB. Regulation of gonadotropins by inhibin and activin. Seminars in Reproductive Medicine. 22: 253-67. PMID 15319828 DOI: 10.1055/S-2004-831901 |
0.487 |
|
| 2004 |
Meysing AU, Kanasaki H, Bedecarrats GY, Acierno JS, Conn PM, Martin KA, Seminara SB, Hall JE, Crowley WF, Kaiser UB. GNRHR mutations in a woman with idiopathic hypogonadotropic hypogonadism highlight the differential sensitivity of luteinizing hormone and follicle-stimulating hormone to gonadotropin-releasing hormone. The Journal of Clinical Endocrinology and Metabolism. 89: 3189-98. PMID 15240592 DOI: 10.1210/Jc.2003-031808 |
0.475 |
|
| 2004 |
Jeong KH, Chin WW, Kaiser UB. Essential role of the homeodomain for pituitary homeobox 1 activation of mouse gonadotropin-releasing hormone receptor gene expression through interactions with c-Jun and DNA. Molecular and Cellular Biology. 24: 6127-39. PMID 15226417 DOI: 10.1128/Mcb.24.14.6127-6139.2004 |
0.589 |
|
| 2004 |
Song IO, Jeong KH, Bakowska JC, Breakefield XO, Kaiser UB. GnRH is expressed in GnRH-deficient hypogonadal (hpg) mice after GnRH gene transfer with a herpes simplex virus (HSV) amplicon vector Fertility and Sterility. 82. DOI: 10.1016/J.Fertnstert.2004.07.840 |
0.338 |
|
| 2003 |
Seminara SB, Messager S, Chatzidaki EE, Thresher RR, Acierno JS, Shagoury JK, Bo-Abbas Y, Kuohung W, Schwinof KM, Hendrick AG, Zahn D, Dixon J, Kaiser UB, Slaugenhaupt SA, Gusella JF, et al. The GPR54 gene as a regulator of puberty. The New England Journal of Medicine. 349: 1614-27. PMID 14573733 DOI: 10.1056/Nejmoa035322 |
0.463 |
|
| 2003 |
Bédécarrats GY, Linher KD, Janovick JA, Beranova M, Kada F, Seminara SB, Michael Conn P, Kaiser UB. Four naturally occurring mutations in the human GnRH receptor affect ligand binding and receptor function. Molecular and Cellular Endocrinology. 205: 51-64. PMID 12890567 DOI: 10.1016/S0303-7207(03)00201-6 |
0.424 |
|
| 2003 |
Bédécarrats GY, O'Neill FH, Norwitz ER, Kaiser UB, Teixeira J. Regulation of gonadotropin gene expression by Mullerian inhibiting substance. Proceedings of the National Academy of Sciences of the United States of America. 100: 9348-53. PMID 12878721 DOI: 10.1073/Pnas.1633592100 |
0.446 |
|
| 2003 |
Bédécarrats GY, Kaiser UB. Differential regulation of gonadotropin subunit gene promoter activity by pulsatile gonadotropin-releasing hormone (GnRH) in perifused L beta T2 cells: role of GnRH receptor concentration. Endocrinology. 144: 1802-11. PMID 12697686 DOI: 10.1210/En.2002-221140 |
0.452 |
|
| 2003 |
Bedecarrats GY, Linher KD, Kaiser UB. Two common naturally occurring mutations in the human gonadotropin-releasing hormone (GnRH) receptor have differential effects on gonadotropin gene expression and on GnRH-mediated signal transduction. The Journal of Clinical Endocrinology and Metabolism. 88: 834-43. PMID 12574221 DOI: 10.1210/Jc.2002-020806 |
0.461 |
|
| 2003 |
Halvorson LM, Horton CD, Kaiser UB, He Z, Jeong K. Transcriptional regulation of the Luteinizing Hormone Beta-Subunit (LHβ) gene by Ptx1 Fertility and Sterility. 80: 20. DOI: 10.1016/S0015-0282(03)01854-5 |
0.358 |
|
| 2002 |
Norwitz ER, Xu S, Jeong KH, Be de Carrats GG, Winebrenner LD, Chin WW, Kaiser UB. Activin A Augments GnRH-Mediated Transcriptional Activation of the Mouse GnRH Receptor Gene. Endocrinology. 143: 985-997. PMID 28204468 DOI: 10.1210/endo.143.3.8663 |
0.31 |
|
| 2002 |
Zakaria MM, Jeong KH, Lacza C, Kaiser UB. Pituitary homeobox 1 activates the rat FSHbeta (rFSHbeta) gene through both direct and indirect interactions with the rFSHbeta gene promoter. Molecular Endocrinology (Baltimore, Md.). 16: 1840-52. PMID 12145338 DOI: 10.1210/Me.2002-0088 |
0.351 |
|
| 2002 |
Norwitz ER, Xu S, Xu J, Spiryda LB, Park JS, Jeong KH, McGee EA, Kaiser UB. Direct binding of AP-1 (Fos/Jun) proteins to a SMAD binding element facilitates both gonadotropin-releasing hormone (GnRH)- and activin-mediated transcriptional activation of the mouse GnRH receptor gene. The Journal of Biological Chemistry. 277: 37469-78. PMID 12145309 DOI: 10.1074/Jbc.M206571200 |
0.401 |
|
| 2002 |
Norwitz ER, Xu S, Jeong KH, Bédécarrats GY, Winebrenner LD, Chin WW, Kaiser UB. Activin A augments GnRH-mediated transcriptional activation of the mouse GnRH receptor gene. Endocrinology. 143: 985-97. PMID 11861523 DOI: 10.1210/Endo.143.3.8663 |
0.615 |
|
| 2001 |
Costa EM, Bedecarrats GY, Mendonca BB, Arnhold IJ, Kaiser UB, Latronico AC. Two novel mutations in the gonadotropin-releasing hormone receptor gene in Brazilian patients with hypogonadotropic hypogonadism and normal olfaction. The Journal of Clinical Endocrinology and Metabolism. 86: 2680-6. PMID 11397871 DOI: 10.1210/Jcem.86.6.7551 |
0.447 |
|
| 2001 |
Beranova M, Oliveira LM, Bédécarrats GY, Schipani E, Vallejo M, Ammini AC, Quintos JB, Hall JE, Martin KA, Hayes FJ, Pitteloud N, Kaiser UB, Crowley WF, Seminara SB. Prevalence, phenotypic spectrum, and modes of inheritance of gonadotropin-releasing hormone receptor mutations in idiopathic hypogonadotropic hypogonadism. The Journal of Clinical Endocrinology and Metabolism. 86: 1580-8. PMID 11297587 DOI: 10.1210/Jcem.86.4.7395 |
0.337 |
|
| 2001 |
Kaiser UB. Editorial: Pituitary gene therapy - Hypotheses on the hypophysis Endocrinology. 142: 528-531. PMID 11159820 DOI: 10.1210/Endo.142.2.8009 |
0.316 |
|
| 2000 |
Kaiser UB, Halvorson LM, Chen MT. Sp1, steroidogenic factor 1 (SF-1), and early growth response protein 1 (egr-1) binding sites form a tripartite gonadotropin-releasing hormone response element in the rat luteinizing hormone-beta gene promoter: an integral role for SF-1. Molecular Endocrinology (Baltimore, Md.). 14: 1235-45. PMID 10935547 DOI: 10.1210/Mend.14.8.0507 |
0.422 |
|
| 1999 |
Halvorson LM, Kaiser UB, Chin WW. The protein kinase C system acts through the early growth response protein 1 to increase LHbeta gene expression in synergy with steroidogenic factor-1. Molecular Endocrinology (Baltimore, Md.). 13: 106-16. PMID 9892016 DOI: 10.1210/Mend.13.1.0216 |
0.593 |
|
| 1998 |
Kaiser UB. Molecular mechanisms of the regulation of gonadotropin gene expression by gonadotropin-releasing hormone. Molecules and Cells. 8: 647-56. PMID 9895115 |
0.36 |
|
| 1998 |
Kaiser UB, Sabbagh E, Chen MT, Chin WW, Saunders BD. Sp1 binds to the rat luteinizing hormone beta (LHbeta) gene promoter and mediates gonadotropin-releasing hormone-stimulated expression of the LHbeta subunit gene. The Journal of Biological Chemistry. 273: 12943-51. PMID 9582327 DOI: 10.1074/Jbc.273.21.12943 |
0.622 |
|
| 1998 |
Kaiser UB, Sabbagh E, Saunders BD, Chin WW. Identification of cis-acting deoxyribonucleic acid elements that mediate gonadotropin-releasing hormone stimulation of the rat luteinizing hormone beta-subunit gene. Endocrinology. 139: 2443-51. PMID 9564856 DOI: 10.1210/Endo.139.5.6003 |
0.629 |
|
| 1998 |
Saunders BD, Sabbagh E, Chin WW, Kaiser UB. Differential use of signal transduction pathways in the gonadotropin-releasing hormone-mediated regulation of gonadotropin subunit gene expression. Endocrinology. 139: 1835-43. PMID 9528969 DOI: 10.1210/Endo.139.4.5972 |
0.635 |
|
| 1997 |
Kaiser UB, Jakubowiak A, Steinberger A, Chin WW. Differential effects of gonadotropin-releasing hormone (GnRH) pulse frequency on gonadotropin subunit and GnRH receptor messenger ribonucleic acid levels in vitro. Endocrinology. 138: 1224-31. PMID 9048630 DOI: 10.1210/Endo.138.3.4968 |
0.586 |
|
| 1997 |
Kaiser UB, Conn PM, Chin WW. Studies of gonadotropin-releasing hormone (GnRH) action using GnRH receptor-expressing pituitary cell lines. Endocrine Reviews. 18: 46-70. PMID 9034786 DOI: 10.1210/Edrv.18.1.0289 |
0.6 |
|
| 1996 |
Penabad JL, Bashey HM, Asa SL, Haddad G, Davis KD, Herbst AB, Gennarelli TA, Kaiser UB, Chin WW, Snyder PJ. Decreased follistatin gene expression in gonadotroph adenomas. The Journal of Clinical Endocrinology and Metabolism. 81: 3397-403. PMID 8784103 DOI: 10.1210/Jcem.81.9.8784103 |
0.573 |
|
| 1996 |
Fernández-Vázquez G, Kaiser UB, Albarracin CT, Chin WW. Transcriptional activation of the gonadotropin-releasing hormone receptor gene by activin A. Molecular Endocrinology (Baltimore, Md.). 10: 356-66. PMID 8721981 DOI: 10.1210/Mend.10.4.8721981 |
0.601 |
|
| 1996 |
Halvorson LM, Kaiser UB, Chin WW. Stimulation of luteinizing hormone beta gene promoter activity by the orphan nuclear receptor, steroidogenic factor-1. The Journal of Biological Chemistry. 271: 6645-50. PMID 8636081 DOI: 10.1074/Jbc.271.12.6645 |
0.61 |
|
| 1995 |
Kaiser UB, Sabbagh E, Katzenellenbogen RA, Conn PM, Chin WW. A mechanism for the differential regulation of gonadotropin subunit gene expression by gonadotropin-releasing hormone. Proceedings of the National Academy of Sciences of the United States of America. 92: 12280-4. PMID 8618885 DOI: 10.1073/Pnas.92.26.12280 |
0.644 |
|
| 1994 |
Kaiser UB, Dushkin H, Altherr MR, Beier DR, Chin WW. Chromosomal localization of the gonadotropin-releasing hormone receptor gene to human chromosome 4q13.1-q21.1 and mouse chromosome 5. Genomics. 20: 506-8. PMID 8034328 DOI: 10.1006/Geno.1994.1211 |
0.554 |
|
| 1994 |
Kuphal D, Janovick JA, Kaiser UB, Chin WW, Conn PM. Stable transfection of GH3 cells with rat gonadotropin-releasing hormone receptor complementary deoxyribonucleic acid results in expression of a receptor coupled to cyclic adenosine 3',5'-monophosphate-dependent prolactin release via a G-protein. Endocrinology. 135: 315-20. PMID 8013367 DOI: 10.1210/Endo.135.1.8013367 |
0.601 |
|
| 1994 |
Albarracin CT, Kaiser UB, Chin WW. Isolation and characterization of the 5'-flanking region of the mouse gonadotropin-releasing hormone receptor gene. Endocrinology. 135: 2300-6. PMID 7988412 DOI: 10.1210/Endo.135.6.7988412 |
0.619 |
|
| 1994 |
Stanislaus D, Janovick JA, Jennes L, Kaiser UB, Chin WW, Conn PM. Functional and morphological characterization of four cell lines derived from GH3 cells stably transfected with gonadotropin-releasing hormone receptor complementary deoxyribonucleic acid. Endocrinology. 135: 2220-7. PMID 7956945 DOI: 10.1210/Endo.135.5.7956945 |
0.566 |
|
| 1994 |
Kaiser UB, Katzenellenbogen RA, Conn PM, Chin WW. Evidence that signalling pathways by which thyrotropin-releasing hormone and gonadotropin-releasing hormone act are both common and distinct. Molecular Endocrinology (Baltimore, Md.). 8: 1038-48. PMID 7527898 DOI: 10.1210/Mend.8.8.7527898 |
0.627 |
|
| 1994 |
Havemann K, Jaques G, Rother J, Hoffmann J, Kaiser U. Receptors of the steroid hormone superfamily in small cell lung cancer (SCLC) cell lines Lung Cancer. 11: 27. DOI: 10.1016/0169-5002(94)93875-X |
0.304 |
|
| 1993 |
Kaiser UB, Chin WW. Regulation of follistatin messenger ribonucleic acid levels in the rat pituitary. The Journal of Clinical Investigation. 91: 2523-31. PMID 8514864 DOI: 10.1172/Jci116488 |
0.564 |
|
| 1993 |
Kaiser UB, Jakubowiak A, Steinberger A, Chin WW. Regulation of rat pituitary gonadotropin-releasing hormone receptor mRNA levels in vivo and in vitro. Endocrinology. 133: 931-4. PMID 8393779 DOI: 10.1210/Endo.133.2.8393779 |
0.59 |
|
| 1992 |
Kaiser UB, Lee BL, Carroll RS, Unabia G, Chin WW, Childs GV. Follistatin gene expression in the pituitary: localization in gonadotropes and folliculostellate cells in diestrous rats. Endocrinology. 130: 3048-56. PMID 1572312 DOI: 10.1210/Endo.130.5.1572312 |
0.584 |
|
| 1992 |
Kaiser UB, Zhao D, Cardona GR, Chin WW. Isolation and characterization of cDNAs encoding the rat pituitary gonadotropin-releasing hormone receptor. Biochemical and Biophysical Research Communications. 189: 1645-52. PMID 1339279 DOI: 10.1016/0006-291X(92)90266-N |
0.583 |
|
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