Guo-Yuan Hu - Publications

Affiliations: 
State Key Laboratory of Drug Research Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, Shanghai Shi, China 
Area:
Neuropharmacology

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Li P, Sun HF, Zhou PZ, Ma CY, Hu GY, Jiang HL, Li M, Liu H, Gao ZB. Comparison of the effects of DC031050, a class III antiarrhythmic agent, on hERG channel and three neuronal potassium channels. Acta Pharmacologica Sinica. 33: 728-36. PMID 22609836 DOI: 10.1038/aps.2012.41  0.592
2011 Chu HY, Wu Q, Zhou S, Cao X, Zhang A, Jin GZ, Hu GY, Zhen X. SKF83959 suppresses excitatory synaptic transmission in rat hippocampus via a dopamine receptor-independent mechanism. Journal of Neuroscience Research. 89: 1259-66. PMID 21538463 DOI: 10.1002/jnr.22653  0.353
2010 Chu HY, Gu Q, Jin GZ, Hu GY, Zhen X. Electrophysiological effects of SKF83959 on hippocampal CA1 pyramidal neurons: potential mechanisms for the drug's neuroprotective effects. Plos One. 5. PMID 20957037 DOI: 10.1371/journal.pone.0013118  0.353
2009 Chen XQ, Zhang J, Neumeyer JL, Jin GZ, Hu GY, Zhang A, Zhen X. Arylbenzazepines are potent modulators for the delayed rectifier K+ channel: a potential mechanism for their neuroprotective effects. Plos One. 4: e5811. PMID 19503734 DOI: 10.1371/Journal.Pone.0005811  0.684
2008 Song MK, Liu H, Jiang HL, Yue JM, Hu GY, Chen HZ. Discovery of talatisamine as a novel specific blocker for the delayed rectifier K+ channels in rat hippocampal neurons. Neuroscience. 155: 469-75. PMID 18601983 DOI: 10.1016/j.neuroscience.2008.06.009  0.607
2008 Gao ZB, Chen XQ, Jiang HL, Liu H, Hu GY. Electrophysiological characterization of a novel Kv channel blocker N,N'-[oxybis(2,1-ethanediyloxy-2,1-ethanediyl) ]bis(4-methyl)-benzenesulfonamide found in virtual screening. Acta Pharmacologica Sinica. 29: 405-12. PMID 18358085 DOI: 10.1111/J.1745-7254.2008.00777.X  0.748
2008 Yang SP, Gao ZB, Wu Y, Hu GY, Yue JM. Chlorahololides C-F: a new class of potent and selective potassium channel blockers from Chloranthus holostegius Tetrahedron. 64: 2027-2034. DOI: 10.1016/j.tet.2007.12.057  0.443
2007 Yu Y, Chen XQ, Cui YY, Hu GY. Electrophysiological actions of cyclosporin A and tacrolimus on rat hippocampal CA1 pyramidal neurons. Acta Pharmacologica Sinica. 28: 1891-7. PMID 18031601 DOI: 10.1111/J.1745-7254.2007.00730.X  0.696
2007 Yu Y, Chen XQ, Cui YY, Hu GY. Calcineurin-independent inhibition of the delayed rectifier K+ current by the immunosuppressant FK506 in rat hippocampal neurons. Brain Research. 1148: 62-8. PMID 17355875 DOI: 10.1016/J.Brainres.2007.02.022  0.73
2007 Yang SP, Gao ZB, Wang FD, Liao SG, Chen HD, Zhang CR, Hu GY, Yue JM. Chlorahololides A and B, two potent and selective blockers of the potassium channel isolated from Chloranthus holostegius. Organic Letters. 9: 903-6. PMID 17263543 DOI: 10.1021/ol0700759  0.493
2007 Liu H, Gao ZB, Yao Z, Zheng S, Li Y, Zhu W, Tan X, Luo X, Shen J, Chen K, Hu GY, Jiang H. Discovering potassium channel blockers from synthetic compound database by using structure-based virtual screening in conjunction with electrophysiological assay. Journal of Medicinal Chemistry. 50: 83-93. PMID 17201412 DOI: 10.1021/Jm060414O  0.614
2006 Gao ZB, Chen XQ, Hu GY. Inhibition of excitatory synaptic transmission by trans-resveratrol in rat hippocampus. Brain Research. 1111: 41-7. PMID 16876771 DOI: 10.1016/J.Brainres.2006.06.096  0.724
2006 Song MK, Liu H, Jiang HL, Yue JM, Hu GY. Electrophysiological characterization of 14-benzoyltalatisamine, a selective blocker of the delayed rectifier K+ channel found in virtual screening. European Journal of Pharmacology. 531: 47-53. PMID 16442097 DOI: 10.1016/J.Ejphar.2005.12.029  0.634
2006 Wang W, Hu GY, Wang YP. Selective modulation of L-type calcium current by magnesium lithospermate B in guinea-pig ventricular myocytes. Life Sciences. 78: 2989-97. PMID 16376948 DOI: 10.1016/j.lfs.2005.11.024  0.371
2005 Gao ZB, Hu GY. Trans-resveratrol, a red wine ingredient, inhibits voltage-activated potassium currents in rat hippocampal neurons. Brain Research. 1056: 68-75. PMID 16112093 DOI: 10.1016/j.brainres.2005.07.013  0.629
2005 Yu B, Hu GY. Donepezil blocks voltage-gated ion channels in rat dissociated hippocampal neurons. European Journal of Pharmacology. 508: 15-21. PMID 15680250 DOI: 10.1016/j.ejphar.2004.12.004  0.439
2004 Zhang N, Chen X, Li M, Cao C, Wang Y, Wu G, Hu G, Wu H. Solution structure of BmKK4, the first member of subfamily α-KTx 17 of scorpion toxins Biochemistry. 43: 12469-12476. PMID 15449936 DOI: 10.1021/Bi0490643  0.458
2004 Wang W, Wang YP, Hu GY. Tetrahydroacridine inhibits voltage-dependent Na(+) current in guinea-pig ventricular myocytes. Acta Pharmacologica Sinica. 25: 1138-44. PMID 15339388  0.327
2004 Li MH, Zhang NX, Chen XQ, Wu G, Wu H, Hu GY. Purification and pharmacological characterization of BmKK2 (alpha-KTx 14.2), a novel potassium channel-blocking peptide, from the venom of Asian scorpion Buthus martensi Karsch. Toxicon : Official Journal of the International Society On Toxinology. 43: 895-900. PMID 15208022 DOI: 10.1016/J.Toxicon.2003.11.028  0.725
2004 Zhang N, Li M, Chen X, Wang Y, Wu G, Hu G, Wu H. Solution structure of BmKK2, a new potassium channel blocker from the venom of Chinese scorpion Buthus martensi Karsch Proteins: Structure, Function and Genetics. 55: 835-845. PMID 15146482 DOI: 10.1002/Prot.20117  0.529
2003 Liu H, Li Y, Song M, Tan X, Cheng F, Zheng S, Shen J, Luo X, Ji R, Yue J, Hu G, Jiang H, Chen K. Structure-based discovery of potassium channel blockers from natural products: Virtual screening and electrophysiological assay testing Chemistry and Biology. 10: 1103-1113. PMID 14652078 DOI: 10.1016/J.Chembiol.2003.10.011  0.611
2003 Li MH, Wang YF, Chen XQ, Zhang NX, Wu HM, Hu GY. BmTx3B, a novel scorpion toxin from Buthus martensi Karsch, inhibits delayed rectifier potassium current in rat hippocampal neurons. Acta Pharmacologica Sinica. 24: 1016-20. PMID 14531945  0.744
2003 Li MH, Zhang NX, Chen XQ, Wu G, Wu HM, Hu GY. BmKK4, a novel toxin from the venom of Asian scorpion Buthus martensi Karsch, inhibits potassium currents in rat hippocampal neurons in vitro. Toxicon : Official Journal of the International Society On Toxinology. 42: 199-205. PMID 12906891 DOI: 10.1016/S0041-0101(03)00136-3  0.737
2003 Zhao XY, Wang Y, Li Y, Chen XQ, Yang HH, Yue JM, Hu GY. Songorine, a diterpenoid alkaloid of the genus Aconitum, is a novel GABA(A) receptor antagonist in rat brain. Neuroscience Letters. 337: 33-6. PMID 12524165 DOI: 10.1016/S0304-3940(02)01299-5  0.683
2002 Li Y, Hu GY. Huperzine A inhibits the sustained potassium current in rat dissociated hippocampal neurons. Neuroscience Letters. 329: 153-6. PMID 12165400 DOI: 10.1016/S0304-3940(02)00620-1  0.439
2002 Hu GY, Biró Z, Hill RH, Grillner S. Intracellular QX-314 causes depression of membrane potential oscillations in lamprey spinal neurons during fictive locomotion. Journal of Neurophysiology. 87: 2676-83. PMID 12037170 DOI: 10.1152/Jn.2002.87.6.2676  0.341
2002 Li Y, Hu GY. Huperzine A, a nootropic agent, inhibits fast transient potassium current in rat dissociated hippocampal neurons. Neuroscience Letters. 324: 25-8. PMID 11983286 DOI: 10.1016/S0304-3940(02)00167-2  0.475
2002 Zhang YH, Zhao XY, Chen XQ, Wang Y, Yang HH, Hu GY. Spermidine antagonizes the inhibitory effect of huperzine A on [3H]dizocilpine (MK-801) binding in synaptic membrane of rat cerebral cortex. Neuroscience Letters. 319: 107-10. PMID 11825682 DOI: 10.1016/S0304-3940(01)02565-4  0.637
2001 Zhang JM, Hu GY. Huperzine A, a nootropic alkaloid, inhibits N-methyl-D-aspartate-induced current in rat dissociated hippocampal neurons. Neuroscience. 105: 663-9. PMID 11516831 DOI: 10.1016/S0306-4522(01)00206-8  0.371
2000 Zhang YH, Chen XQ, Yang HH, Jin GY, Bai DL, Hu GY. Similar potency of the enantiomers of huperzine A in inhibition of [(3)H]dizocilpine (MK-801) binding in rat cerebral cortex. Neuroscience Letters. 295: 116-8. PMID 11090988 DOI: 10.1016/S0304-3940(00)01615-3  0.632
1999 Wang XD, Chen XQ, Yang HH, Hu GY. Comparison of the effects of cholinesterase inhibitors on [3H]MK-801 binding in rat cerebral cortex. Neuroscience Letters. 272: 21-4. PMID 10507533 DOI: 10.1016/S0304-3940(99)00567-4  0.634
1999 Wang XD, Zhang JM, Yang HH, Hu GY. Modulation of NMDA receptor by huperzine A in rat cerebral cortex. Zhongguo Yao Li Xue Bao = Acta Pharmacologica Sinica. 20: 31-5. PMID 10437121  0.312
1998 Pang ZP, Xu TL, Hu GY, Li JS. Dual effects of pentobarbital on rat sacral dorsal commissural neurons in vitro. Zhongguo Yao Li Xue Bao = Acta Pharmacologica Sinica. 19: 327-31. PMID 10375777  0.315
1998 Wu G, Wei DS, He FH, Hu GY, Wu HM. A K+ channel-blocking peptide from venom of Chinese scorpion Buthus martensii Karsch. Zhongguo Yao Li Xue Bao = Acta Pharmacologica Sinica. 19: 317-21. PMID 10375775  0.34
1996 Chen W, Zhang JJ, Hu GY, Wu CP. Different mechanisms underlying the repolarization of narrow and wide action potentials in pyramidal cells and interneurons of cat motor cortex. Neuroscience. 73: 57-68. PMID 8783229 DOI: 10.1016/0306-4522(96)00010-3  0.356
1996 Figenschou A, Hu GY, Storm JF. Cholinergic modulation of the action potential in rat hippocampal neurons. The European Journal of Neuroscience. 8: 211-9. PMID 8713465 DOI: 10.1111/j.1460-9568.1996.tb01182.x  0.659
1995 Chen W, Zhang JJ, Hu GY, Wu CP. GABAA receptor-mediated feedback inhibition in pyramidal neurons of cat motor cortex. Neuroscience Letters. 198: 123-6. PMID 8592636 DOI: 10.1016/0304-3940(95)11993-7  0.323
1992 Hu GY, Hvalby O, Lacaille JC, Piercey B, Ostberg T, Andersen P. Synaptically triggered action potentials begin as a depolarizing ramp in rat hippocampal neurones in vitro. The Journal of Physiology. 453: 663-87. PMID 1464850 DOI: 10.1113/jphysiol.1992.sp019250  0.652
1992 Hu GY, Hvalby O. Glutamate-induced action potentials are preceded by regenerative prepotentials in rat hippocampal pyramidal cells in vitro. Experimental Brain Research. 88: 485-94. PMID 1350250 DOI: 10.1007/BF00228178  0.328
1992 Hu GY, Storm JF. 2-Amino-3-phosphonopropionate fails to block postsynaptic effects of metabotropic glutamate receptors in rat hippocampal neurones. Acta Physiologica Scandinavica. 145: 187-91. PMID 1322019 DOI: 10.1111/j.1748-1716.1992.tb09354.x  0.647
1991 Hu GY. Effects of depolarization and QX-314 injection on slow prepotentials in rat hippocampal pyramidal neurones in vitro. Acta Physiologica Scandinavica. 141: 235-40. PMID 2048409 DOI: 10.1111/j.1748-1716.1991.tb09073.x  0.365
1991 Hu GY, Storm JF. Excitatory amino acids acting on metabotropic glutamate receptors broaden the action potential in hippocampal neurons. Brain Research. 568: 339-44. PMID 1687672 DOI: 10.1016/0006-8993(91)91423-X  0.636
1987 Hu GY, Hvalby O, Walaas SI, Albert KA, Skjeflo P, Andersen P, Greengard P. Protein kinase C injection into hippocampal pyramidal cells elicits features of long term potentiation. Nature. 328: 426-9. PMID 3614346 DOI: 10.1038/328426a0  0.451
1987 Hvalby O, Lacaille JC, Hu GY, Andersen P. Postsynaptic long-term potentiation follows coupling of dendritic glutamate application and synaptic activation. Experientia. 43: 599-601. PMID 2885212 DOI: 10.1007/BF02126343  0.602
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