Philip Thomas - Publications

Affiliations: 
NPP University College London, London, United Kingdom 
Area:
GABA(A), Synaptic electrophysiology

23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Field M, Dorovykh V, Thomas P, Smart TG. Physiological role for GABA receptor desensitization in the induction of long-term potentiation at inhibitory synapses. Nature Communications. 12: 2112. PMID 33837214 DOI: 10.1038/s41467-021-22420-9  0.649
2019 Hannan S, Minere M, Harris J, Izquierdo P, Thomas P, Tench B, Smart TG. GABAR isoform and subunit structural motifs determine synaptic and extrasynaptic receptor localisation. Neuropharmacology. PMID 30794836 DOI: 10.1016/J.Neuropharm.2019.02.022  0.748
2018 Seljeset S, Bright DP, Thomas P, Smart TG. Probing GABAreceptors with inhibitory neurosteroids. Neuropharmacology. PMID 29447845 DOI: 10.1016/J.Neuropharm.2018.02.008  0.8
2017 Laverty D, Thomas P, Field M, Andersen OJ, Gold MG, Biggin PC, Gielen M, Smart TG. Crystal structures of a GABAA-receptor chimera reveal new endogenous neurosteroid-binding sites. Nature Structural & Molecular Biology. PMID 28967882 DOI: 10.1038/Nsmb.3477  0.67
2015 He Q, Duguid I, Clark B, Panzanelli P, Patel B, Thomas P, Fritschy JM, Smart TG. Interneuron- and GABAA receptor-specific inhibitory synaptic plasticity in cerebellar Purkinje cells. Nature Communications. 6: 7364. PMID 26179122 DOI: 10.1038/Ncomms8364  0.761
2015 Hausrat TJ, Muhia M, Gerrow K, Thomas P, Hirdes W, Tsukita S, Heisler FF, Herich L, Dubroqua S, Breiden P, Feldon J, Schwarz JR, Yee BK, Smart TG, Triller A, et al. Radixin regulates synaptic GABAA receptor density and is essential for reversal learning and short-term memory. Nature Communications. 6: 6872. PMID 25891999 DOI: 10.1038/Ncomms7872  0.612
2015 Gielen M, Thomas P, Smart TG. The desensitization gate of inhibitory Cys-loop receptors. Nature Communications. 6: 6829. PMID 25891813 DOI: 10.1038/Ncomms7829  0.697
2015 Adams JM, Thomas P, Smart TG. Modulation of neurosteroid potentiation by protein kinases at synaptic- and extrasynaptic-type GABAA receptors. Neuropharmacology. 88: 63-73. PMID 25278033 DOI: 10.1016/J.Neuropharm.2014.09.021  0.737
2013 Anstee QM, Knapp S, Maguire EP, Hosie AM, Thomas P, Mortensen M, Bhome R, Martinez A, Walker SE, Dixon CI, Ruparelia K, Montagnese S, Kuo YT, Herlihy A, Bell JD, et al. Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition. Nature Communications. 4: 2816. PMID 24281383 DOI: 10.1038/Ncomms3816  0.742
2013 Hannan S, Wilkins ME, Thomas P, Smart TG. Tracking cell surface mobility of GPCRs using α-bungarotoxin-linked fluorophores. Methods in Enzymology. 521: 109-29. PMID 23351736 DOI: 10.1016/B978-0-12-391862-8.00006-5  0.805
2012 Thomas P, Smart TG. Use of electrophysiological methods in the study of recombinant and native neuronal ligand-gated ion channels. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. Unit 11.4. PMID 23258597 DOI: 10.1002/0471141755.ph1104s59  0.635
2011 Hannan S, Wilkins ME, Dehghani-Tafti E, Thomas P, Baddeley SM, Smart TG. Gamma-aminobutyric acid type B (GABA(B)) receptor internalization is regulated by the R2 subunit. The Journal of Biological Chemistry. 286: 24324-35. PMID 21724853 DOI: 10.1074/Jbc.M110.220814  0.791
2011 Hannan S, Wilkins ME, Dehghani-Tafti E, Thomas P, Baddeley SM, Smart TG. GABAB receptor internalisation is regulated by the R2 subunit. The Journal of Biological Chemistry. PMID 21540186 DOI: 10.1074/Jbc.M111.220814  0.784
2006 Rees MI, Harvey K, Pearce BR, Chung SK, Duguid IC, Thomas P, Beatty S, Graham GE, Armstrong L, Shiang R, Abbott KJ, Zuberi SM, Stephenson JB, Owen MJ, Tijssen MA, et al. Mutations in the gene encoding GlyT2 (SLC6A5) define a presynaptic component of human startle disease. Nature Genetics. 38: 801-6. PMID 16751771 DOI: 10.1038/Ng1814  0.718
2005 Thomas P, Mortensen M, Hosie AM, Smart TG. Dynamic mobility of functional GABAA receptors at inhibitory synapses. Nature Neuroscience. 8: 889-97. PMID 15951809 DOI: 10.1038/Nn1483  0.795
2005 Thomas P, Smart TG. HEK293 cell line: a vehicle for the expression of recombinant proteins. Journal of Pharmacological and Toxicological Methods. 51: 187-200. PMID 15862464 DOI: 10.1016/J.Vascn.2004.08.014  0.502
2004 Kittler JT, Thomas P, Tretter V, Bogdanov YD, Haucke V, Smart TG, Moss SJ. Huntingtin-associated protein 1 regulates inhibitory synaptic transmission by modulating gamma-aminobutyric acid type A receptor membrane trafficking. Proceedings of the National Academy of Sciences of the United States of America. 101: 12736-41. PMID 15310851 DOI: 10.1073/Pnas.0401860101  0.696
2004 Jovanovic JN, Thomas P, Kittler JT, Smart TG, Moss SJ. Brain-derived neurotrophic factor modulates fast synaptic inhibition by regulating GABA(A) receptor phosphorylation, activity, and cell-surface stability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 522-30. PMID 14724252 DOI: 10.1523/Jneurosci.3606-03.2004  0.693
2002 Thomas P, Smart TG. Use of electrophysiological methods in the study of recombinant and native neuronal ligand-gated ion channels. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. Unit 11.4. PMID 22294075 DOI: 10.1002/0471141755.Ph1104S17  0.582
2002 Couve A, Thomas P, Calver AR, Hirst WD, Pangalos MN, Walsh FS, Smart TG, Moss SJ. Cyclic AMP-dependent protein kinase phosphorylation facilitates GABA(B) receptor-effector coupling. Nature Neuroscience. 5: 415-24. PMID 11976702 DOI: 10.1038/Nn833  0.68
2001 Bedford FK, Kittler JT, Muller E, Thomas P, Uren JM, Merlo D, Wisden W, Triller A, Smart TG, Moss SJ. GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1. Nature Neuroscience. 4: 908-16. PMID 11528422 DOI: 10.1038/Nn0901-908  0.689
1999 Harvey RJ, Thomas P, James CH, Wilderspin A, Smart TG. Identification of an inhibitory Zn2+ binding site on the human glycine receptor alpha1 subunit. The Journal of Physiology. 520: 53-64. PMID 10517800 DOI: 10.1111/J.1469-7793.1999.00053.X  0.592
1999 Taylor PM, Thomas P, Gorrie GH, Connolly CN, Smart TG, Moss SJ. Identification of amino acid residues within GABA(A) receptor beta subunits that mediate both homomeric and heteromeric receptor expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 6360-71. PMID 10414965 DOI: 10.1523/Jneurosci.19-15-06360.1999  0.637
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