Philip Thomas - Publications

NPP University College London, London, United Kingdom 
GABA(A), Synaptic electrophysiology

39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Hannan S, Minere M, Harris J, Izquierdo P, Thomas P, Tench B, Smart TG. GABAR isoform and subunit structural motifs determine synaptic and extrasynaptic receptor localisation. Neuropharmacology. PMID 30794836 DOI: 10.1016/j.neuropharm.2019.02.022  1
2018 Seljeset S, Bright DP, Thomas P, Smart TG. Probing GABAreceptors with inhibitory neurosteroids. Neuropharmacology. PMID 29447845 DOI: 10.1016/j.neuropharm.2018.02.008  1
2017 Laverty D, Thomas P, Field M, Andersen OJ, Gold MG, Biggin PC, Gielen M, Smart TG. Crystal structures of a GABAA-receptor chimera reveal new endogenous neurosteroid-binding sites. Nature Structural & Molecular Biology. PMID 28967882 DOI: 10.1038/nsmb.3477  1
2015 Singh MD, Thomas P, Owens J, Hague W, Fenech M. Potential role of folate in pre-eclampsia. Nutrition Reviews. 73: 694-722. PMID 26359215 DOI: 10.1093/nutrit/nuv028  1
2015 Thomas P, Fenech M. Buccal Cytome Biomarkers and Their Association with Plasma Folate, Vitamin B12 and Homocysteine in Alzheimer's Disease. Journal of Nutrigenetics and Nutrigenomics. 8: 57-69. PMID 26228832 DOI: 10.1159/000435784  1
2015 He Q, Duguid I, Clark B, Panzanelli P, Patel B, Thomas P, Fritschy JM, Smart TG. Interneuron- and GABAA receptor-specific inhibitory synaptic plasticity in cerebellar Purkinje cells. Nature Communications. 6: 7364. PMID 26179122 DOI: 10.1038/ncomms8364  1
2015 Hausrat TJ, Muhia M, Gerrow K, Thomas P, Hirdes W, Tsukita S, Heisler FF, Herich L, Dubroqua S, Breiden P, Feldon J, Schwarz JR, Yee BK, Smart TG, Triller A, et al. Radixin regulates synaptic GABAA receptor density and is essential for reversal learning and short-term memory. Nature Communications. 6: 6872. PMID 25891999 DOI: 10.1038/ncomms7872  1
2015 Gielen M, Thomas P, Smart TG. The desensitization gate of inhibitory Cys-loop receptors. Nature Communications. 6: 6829. PMID 25891813 DOI: 10.1038/ncomms7829  1
2015 Chua A, Thomas P, Clifton P, Fenech M. Chromosomal DNA damage in APOE ɛ4 carriers and noncarriers does not appear to be different. Environmental and Molecular Mutagenesis. PMID 25820038 DOI: 10.1002/em.21949  1
2015 Bolognesi C, Roggieri P, Ropolo M, Thomas P, Hor M, Fenech M, Nersesyan A, Knasmueller S. Buccal micronucleus cytome assay: results of an intra- and inter-laboratory scoring comparison. Mutagenesis. 30: 545-55. PMID 25795005 DOI: 10.1093/mutage/gev017  1
2015 Sharif R, Thomas P, Zalewski P, Fenech M. Zinc supplementation influences genomic stability biomarkers, antioxidant activity, and zinc transporter genes in an elderly Australian population with low zinc status. Molecular Nutrition & Food Research. 59: 1200-12. PMID 25755079 DOI: 10.1002/mnfr.201400784  1
2015 Main PA, Thomas P, Angley MT, Young R, Esterman A, King CE, Fenech MF. Lack of evidence for genomic instability in autistic children as measured by the cytokinesis-block micronucleus cytome assay. Autism Research : Official Journal of the International Society For Autism Research. 8: 94-104. PMID 25371234 DOI: 10.1002/aur.1428  1
2015 Adams JM, Thomas P, Smart TG. Modulation of neurosteroid potentiation by protein kinases at synaptic- and extrasynaptic-type GABAA receptors. Neuropharmacology. 88: 63-73. PMID 25278033 DOI: 10.1016/j.neuropharm.2014.09.021  1
2015 Lee SL, Thomas P, Hecker J, Faunt J, Fenech M. Chromosomal DNA damage measured using the cytokinesis-block micronucleus cytome assay is significantly associated with cognitive impairment in South Australians. Environmental and Molecular Mutagenesis. 56: 32-40. PMID 25099033 DOI: 10.1002/em.21890  1
2014 François M, Leifert W, Martins R, Thomas P, Fenech M. Biomarkers of Alzheimer's disease risk in peripheral tissues; focus on buccal cells. Current Alzheimer Research. 11: 519-31. PMID 24938500 DOI: 10.2174/1567205011666140618103827  1
2014 Chua A, Thomas P, Wijesundera C, Clifton P, Fenech M. Effect of docosahexaenoic acid and furan fatty acids on cytokinesis block micronucleus cytome assay biomarkers in astrocytoma cell lines under conditions of oxidative stress. Environmental and Molecular Mutagenesis. 55: 573-90. PMID 24828973 DOI: 10.1002/em.21873  1
2014 François M, Leifert W, Hecker J, Faunt J, Martins R, Thomas P, Fenech M. Altered cytological parameters in buccal cells from individuals with mild cognitive impairment and Alzheimer's disease. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 85: 698-708. PMID 24616437 DOI: 10.1002/cyto.a.22453  1
2014 Bruschweiler ED, Hopf NB, Wild P, Huynh CK, Fenech M, Thomas P, Hor M, Charriere N, Savova-Bianchi D, Danuser B. Workers exposed to wood dust have an increased micronucleus frequency in nasal and buccal cells: results from a pilot study. Mutagenesis. 29: 201-7. PMID 24603450 DOI: 10.1093/mutage/geu003  1
2014 Gonçalves TS, Menezes LM, Trindade C, Machado Mda S, Thomas P, Fenech M, Henriques JA. Cytotoxicity and genotoxicity of orthodontic bands with or without silver soldered joints. Mutation Research. Genetic Toxicology and Environmental Mutagenesis. 762: 1-8. PMID 24495929 DOI: 10.1016/j.mrgentox.2014.01.011  1
2014 Lee SL, Thomas P, Fenech M. Extracellular amyloid beta 42 causes necrosis, inhibition of nuclear division, and mitotic disruption under both folate deficient and folate replete conditions as measured by the cytokinesis-block micronucleus cytome assay. Environmental and Molecular Mutagenesis. 55: 1-14. PMID 24038346 DOI: 10.1002/em.21811  1
2013 Anstee QM, Knapp S, Maguire EP, Hosie AM, Thomas P, Mortensen M, Bhome R, Martinez A, Walker SE, Dixon CI, Ruparelia K, Montagnese S, Kuo YT, Herlihy A, Bell JD, et al. Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition. Nature Communications. 4: 2816. PMID 24281383 DOI: 10.1038/ncomms3816  1
2013 Bolognesi C, Knasmueller S, Nersesyan A, Thomas P, Fenech M. The HUMNxl scoring criteria for different cell types and nuclear anomalies in the buccal micronucleus cytome assay - an update and expanded photogallery. Mutation Research. 753: 100-13. PMID 23942275 DOI: 10.1016/j.mrrev.2013.07.002  1
2013 Main PA, Thomas P, Esterman A, Fenech MF. Necrosis is increased in lymphoblastoid cell lines from children with autism compared with their non-autistic siblings under conditions of oxidative and nitrosative stress. Mutagenesis. 28: 475-84. PMID 23766106 DOI: 10.1093/mutage/get025  1
2013 Hannan S, Wilkins ME, Thomas P, Smart TG. Tracking cell surface mobility of GPCRs using α-bungarotoxin-linked fluorophores. Methods in Enzymology. 521: 109-29. PMID 23351736 DOI: 10.1016/B978-0-12-391862-8.00006-5  1
2013 Sakulnarmrat K, Fenech M, Thomas P, Konczak I. Cytoprotective and pro-apoptotic activities of native Australian herbs polyphenolic-rich extracts. Food Chemistry. 136: 9-17. PMID 23017386 DOI: 10.1016/j.foodchem.2012.07.089  1
2012 Thomas P, Smart TG. Use of electrophysiological methods in the study of recombinant and native neuronal ligand-gated ion channels. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. Unit 11.4. PMID 23258597 DOI: 10.1002/0471141755.ph1104s59  1
2012 Main PA, Angley MT, O'Doherty CE, Thomas P, Fenech M. The potential role of the antioxidant and detoxification properties of glutathione in autism spectrum disorders: a systematic review and meta-analysis. Nutrition & Metabolism. 9: 35. PMID 22524510 DOI: 10.1186/1743-7075-9-35  1
2012 Sharif R, Thomas P, Zalewski P, Fenech M. The role of zinc in genomic stability. Mutation Research. 733: 111-21. PMID 21939673 DOI: 10.1016/j.mrfmmm.2011.08.009  1
2012 Sharif R, Thomas P, Zalewski P, Fenech M. Zinc deficiency or excess within the physiological range increases genome instability and cytotoxicity, respectively, in human oral keratinocyte cells. Genes & Nutrition. 7: 139-54. PMID 21935692 DOI: 10.1007/s12263-011-0248-4  1
2011 Bonassi S, Coskun E, Ceppi M, Lando C, Bolognesi C, Burgaz S, Holland N, Kirsh-Volders M, Knasmueller S, Zeiger E, Carnesoltas D, Cavallo D, da Silva J, de Andrade VM, Demircigil GC, ... ... Thomas P, et al. The HUman MicroNucleus project on eXfoLiated buccal cells (HUMN XL): The role of life-style, host factors, occupational exposures, health status, and assay protocol Mutation Research - Reviews in Mutation Research. 728: 88-97. PMID 21763453 DOI: 10.1016/j.mrrev.2011.06.005  1
2011 Hannan S, Wilkins ME, Dehghani-Tafti E, Thomas P, Baddeley SM, Smart TG. Gamma-aminobutyric acid type B (GABA(B)) receptor internalization is regulated by the R2 subunit. The Journal of Biological Chemistry. 286: 24324-35. PMID 21724853 DOI: 10.1074/jbc.M110.220814  1
2011 Leifert WR, François M, Thomas P, Luther E, Holden E, Fenech M. Automation of the buccal micronucleus cytome assay using laser scanning cytometry. Methods in Cell Biology. 102: 321-39. PMID 21704845 DOI: 10.1016/B978-0-12-374912-3.00013-4  1
2011 Hannan S, Wilkins ME, Dehghani-Tafti E, Thomas P, Baddeley SM, Smart TG. GABAB receptor internalisation is regulated by the R2 subunit. The Journal of Biological Chemistry. PMID 21540186 DOI: 10.1074/jbc.M111.220814  1
2006 Rees MI, Harvey K, Pearce BR, Chung SK, Duguid IC, Thomas P, Beatty S, Graham GE, Armstrong L, Shiang R, Abbott KJ, Zuberi SM, Stephenson JB, Owen MJ, Tijssen MA, et al. Mutations in the gene encoding GlyT2 (SLC6A5) define a presynaptic component of human startle disease. Nature Genetics. 38: 801-6. PMID 16751771 DOI: 10.1038/ng1814  1
2005 Thomas P, Mortensen M, Hosie AM, Smart TG. Dynamic mobility of functional GABAA receptors at inhibitory synapses. Nature Neuroscience. 8: 889-97. PMID 15951809 DOI: 10.1038/nn1483  1
2005 Thomas P, Smart TG. HEK293 cell line: a vehicle for the expression of recombinant proteins. Journal of Pharmacological and Toxicological Methods. 51: 187-200. PMID 15862464 DOI: 10.1016/j.vascn.2004.08.014  1
2004 Kittler JT, Thomas P, Tretter V, Bogdanov YD, Haucke V, Smart TG, Moss SJ. Huntingtin-associated protein 1 regulates inhibitory synaptic transmission by modulating gamma-aminobutyric acid type A receptor membrane trafficking. Proceedings of the National Academy of Sciences of the United States of America. 101: 12736-41. PMID 15310851 DOI: 10.1073/pnas.0401860101  1
2004 Jovanovic JN, Thomas P, Kittler JT, Smart TG, Moss SJ. Brain-derived neurotrophic factor modulates fast synaptic inhibition by regulating GABA(A) receptor phosphorylation, activity, and cell-surface stability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 522-30. PMID 14724252 DOI: 10.1523/JNEUROSCI.3606-03.2004  1
2002 Thomas P, Smart TG. Use of electrophysiological methods in the study of recombinant and native neuronal ligand-gated ion channels. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. Unit 11.4. PMID 22294075 DOI: 10.1002/0471141755.ph1104s17  1
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