Martin Mortensen - Publications

Affiliations: 
NPP University College London, London, United Kingdom 

30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Sui Y, Mortensen M, Yuan B, Nicholson MW, Smart TG, Jovanovic JN. GABA receptors and neuroligin 2 synergize to promote synaptic adhesion and inhibitory synaptogenesis. Frontiers in Cellular Neuroscience. 18: 1423471. PMID 39100896 DOI: 10.3389/fncel.2024.1423471  0.658
2024 Minere M, Mortensen M, Dorovykh V, Warnes G, Nizetic D, Smart TG, Hannan SB. Presynaptic hyperexcitability reversed by positive allosteric modulation of a GABABR epilepsy variant. Brain : a Journal of Neurology. PMID 39028675 DOI: 10.1093/brain/awae232  0.734
2024 Mortensen M, Bright DP, Fagotti J, Dorovykh V, Cerna B, Smart TG. Forty Years Searching for Neurosteroid Binding Sites on GABA Receptors. Neuroscience. PMID 38852898 DOI: 10.1016/j.neuroscience.2024.06.002  0.818
2023 Mortensen M, Xu Y, Shehata MA, Krall J, Ernst M, Frølund B, Smart TG. Pregnenolone sulphate analogues differentially modulate GABA receptor closed/desensitised states. British Journal of Pharmacology. PMID 37194503 DOI: 10.1111/bph.16143  0.713
2022 Kasaragod VB, Mortensen M, Hardwick SW, Wahid AA, Dorovykh V, Chirgadze DY, Smart TG, Miller PS. Publisher Correction: Mechanisms of inhibition and activation of extrasynaptic αβ GABA receptors. Nature. PMID 35332337 DOI: 10.1038/s41586-022-04663-8  0.761
2022 Kasaragod VB, Mortensen M, Hardwick SW, Wahid AA, Dorovykh V, Chirgadze DY, Smart TG, Miller PS. Mechanisms of inhibition and activation of extrasynaptic αβ GABA receptors. Nature. 602: 529-533. PMID 35140402 DOI: 10.1038/s41586-022-04402-z  0.782
2021 Sexton CA, Penzinger R, Mortensen M, Bright DP, Smart TG. Structural determinants and regulation of spontaneous activity in GABA receptors. Nature Communications. 12: 5457. PMID 34526505 DOI: 10.1038/s41467-021-25633-0  0.809
2020 Mortensen M, Huckvale R, Pandurangan AP, Baker JR, Smart TG. Optopharmacology reveals a differential contribution of native GABA receptors to dendritic and somatic inhibition using azogabazine. Neuropharmacology. 108135. PMID 32445639 DOI: 10.1016/J.Neuropharm.2020.108135  0.71
2019 Mortensen M, Krall J, Kongstad KT, Brygger BM, Lenzi O, Francotte P, Sørensen TE, Nielsen B, Jensen AA, Smart TG, Frølund B. Developing new 4-PIOL and 4-PHP analogues for photo-inactivation of γ-aminobutyric acid type A receptors. Acs Chemical Neuroscience. PMID 31589403 DOI: 10.1021/Acschemneuro.9B00478  0.705
2016 Huckvale R, Mortensen M, Pryde D, Smart TG, Baker JR. Azogabazine; a photochromic antagonist of the GABAA receptor. Organic & Biomolecular Chemistry. PMID 27327397 DOI: 10.1039/C6Ob01101B  0.685
2016 Patel B, Bright DP, Mortensen M, Frølund B, Smart TG. Context-Dependent Modulation of GABAAR-Mediated Tonic Currents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 607-21. PMID 26758848 DOI: 10.1523/Jneurosci.2047-15.2016  0.818
2015 Mortensen M, Smart TG. Neuronal Inhibition under the Spotlight. Neuron. 88: 845-7. PMID 26637790 DOI: 10.1016/J.Neuron.2015.11.014  0.657
2015 Murray A, Letourneau A, Canzonetta C, Stathaki E, Gimelli S, Sloan-Bena F, Abrehart R, Goh P, Lim S, Baldo C, Dagna-Bricarelli F, Hannan S, Mortensen M, Ballard D, Syndercombe Court D, et al. Brief report: isogenic induced pluripotent stem cell lines from an adult with mosaic down syndrome model accelerated neuronal ageing and neurodegeneration. Stem Cells (Dayton, Ohio). 33: 2077-84. PMID 25694335 DOI: 10.1002/Stem.1968  0.653
2015 Hannan S, Mortensen M, Smart TG. Snake neurotoxin α-bungarotoxin is an antagonist at native GABA(A) receptors. Neuropharmacology. 93: 28-40. PMID 25634239 DOI: 10.1016/J.Neuropharm.2015.01.001  0.791
2014 Mortensen M, Iqbal F, Pandurangan AP, Hannan S, Huckvale R, Topf M, Baker JR, Smart TG. Photo-antagonism of the GABAA receptor. Nature Communications. 5: 4454. PMID 25072879 DOI: 10.1038/Ncomms5454  0.788
2014 Patel B, Mortensen M, Smart TG. Stoichiometry of δ subunit containing GABA(A) receptors. British Journal of Pharmacology. 171: 985-94. PMID 24206220 DOI: 10.1111/Bph.12514  0.733
2013 Anstee QM, Knapp S, Maguire EP, Hosie AM, Thomas P, Mortensen M, Bhome R, Martinez A, Walker SE, Dixon CI, Ruparelia K, Montagnese S, Kuo YT, Herlihy A, Bell JD, et al. Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition. Nature Communications. 4: 2816. PMID 24281383 DOI: 10.1038/Ncomms3816  0.744
2011 Mortensen M, Patel B, Smart TG. GABA Potency at GABA(A) Receptors Found in Synaptic and Extrasynaptic Zones. Frontiers in Cellular Neuroscience. 6: 1. PMID 22319471 DOI: 10.3389/Fncel.2012.00001  0.755
2011 Iqbal F, Ellwood R, Mortensen M, Smart TG, Baker JR. Synthesis and evaluation of highly potent GABA(A) receptor antagonists based on gabazine (SR-95531). Bioorganic & Medicinal Chemistry Letters. 21: 4252-4. PMID 21664131 DOI: 10.1016/J.Bmcl.2011.05.067  0.717
2010 Mortensen M, Ebert B, Wafford K, Smart TG. Distinct activities of GABA agonists at synaptic- and extrasynaptic-type GABAA receptors. The Journal of Physiology. 588: 1251-68. PMID 20176630 DOI: 10.1113/Jphysiol.2009.182444  0.739
2007 Mortensen M, Smart TG. Single-channel recording of ligand-gated ion channels. Nature Protocols. 2: 2826-41. PMID 18007618 DOI: 10.1038/Nprot.2007.403  0.539
2006 Mortensen M, Smart TG. Extrasynaptic alphabeta subunit GABAA receptors on rat hippocampal pyramidal neurons. The Journal of Physiology. 577: 841-56. PMID 17023503 DOI: 10.1113/Jphysiol.2006.117952  0.765
2005 Thomas P, Mortensen M, Hosie AM, Smart TG. Dynamic mobility of functional GABAA receptors at inhibitory synapses. Nature Neuroscience. 8: 889-97. PMID 15951809 DOI: 10.1038/Nn1483  0.8
2004 Mortensen M, Kristiansen U, Ebert B, Frølund B, Krogsgaard-Larsen P, Smart TG. Activation of single heteromeric GABA(A) receptor ion channels by full and partial agonists. The Journal of Physiology. 557: 389-413. PMID 14990676 DOI: 10.1113/Jphysiol.2003.054734  0.715
2003 Mortensen M, Wafford KA, Wingrove P, Ebert B. Pharmacology of GABA(A) receptors exhibiting different levels of spontaneous activity. European Journal of Pharmacology. 476: 17-24. PMID 12969744 DOI: 10.1016/S0014-2999(03)02125-3  0.629
2002 Mortensen M, Frølund B, Jørgensen AT, Liljefors T, Krogsgaard-Larsen P, Ebert B. Activity of novel 4-PIOL analogues at human alpha 1 beta 2 gamma 2S GABA(A) receptors--correlation with hydrophobicity. European Journal of Pharmacology. 451: 125-32. PMID 12231381 DOI: 10.1016/S0014-2999(02)02271-9  0.545
2002 Ebert B, i Storustovu S, Mortensen M, Frølund B. Characterization of GABA(A) receptor ligands in the rat cortical wedge preparation: evidence for action at extrasynaptic receptors? British Journal of Pharmacology. 137: 1-8. PMID 12183325 DOI: 10.1038/Sj.Bjp.0704846  0.595
2002 Ragnarsson L, Mortensen M, Dodd PR, Lewis RJ. Spermine modulation of the glutamate(NMDA) receptor is differentially responsive to conantokins in normal and Alzheimer's disease human cerebral cortex. Journal of Neurochemistry. 81: 765-79. PMID 12065636 DOI: 10.1046/J.1471-4159.2002.00872.X  0.39
2001 Ebert B, Mortensen M, Thompson SA, Kehler J, Wafford KA, Krogsgaard-Larsen P. Bioisosteric determinants for subtype selectivity of ligands for heteromeric GABA(A) receptors. Bioorganic & Medicinal Chemistry Letters. 11: 1573-7. PMID 11412984 DOI: 10.1016/S0960-894X(01)00184-6  0.626
1999 Mortensen M, Matsumoto I, Niwa S, Dodd PR. The modulatory effect of spermine on the glutamate-NMDA receptor is regionally variable in normal human adult cerebral cortex. Pharmacology & Toxicology. 84: 135-42. PMID 10193675 DOI: 10.1111/J.1600-0773.1999.Tb00889.X  0.329
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