Vijayalakshmi Santhakumar, MD, PhD - Publications

Affiliations: 
Neuroscience University of Medicine and Dentistry of New Jersey, Piscataway Township, New Jersey, United States 

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Gupta A, Dovek L, Proddutur A, Elgammal FS, Santhakumar V. Long-Term Effects of Moderate Concussive Brain Injury During Adolescence on Synaptic and Tonic GABA Currents in Dentate Granule Cells and Semilunar Granule Cells. Frontiers in Neuroscience. 16: 800733. PMID 35360164 DOI: 10.3389/fnins.2022.800733  0.816
2022 Afrasiabi M, Gupta A, Xu H, Swietek B, Santhakumar V. Differential Activity-Dependent Increase in Synaptic Inhibition and Parvalbumin Interneuron Recruitment in Dentate Granule Cells and Semilunar Granule Cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34980636 DOI: 10.1523/JNEUROSCI.1360-21.2021  0.748
2021 Ubina T, Vahedi-Hunter T, Agnew-Svoboda W, Wong W, Gupta A, Santhakumar V, Riccomagno MM. ExBoX: a simple Boolean exclusion strategy to drive expression in neurons. Journal of Cell Science. PMID 34515305 DOI: 10.1242/jcs.257212  0.658
2020 Gupta A, Proddutur A, Chang YJ, Raturi V, Guevarra J, Shah Y, Elgammal FS, Santhakumar V. Dendritic morphology and inhibitory regulation distinguish dentate semilunar granule cells from granule cells through distinct stages of postnatal development. Brain Structure & Function. PMID 33124674 DOI: 10.1007/s00429-020-02162-y  0.784
2020 Korgaonkar AA, Nguyen S, Li Y, Sekhar D, Subramanian D, Guevarra J, Pang KCH, Santhakumar V. Distinct cellular mediators drive the Janus Faces of Toll-like Receptor 4 regulation of network excitability which impacts working memory performance after brain Injury. Brain, Behavior, and Immunity. PMID 32259563 DOI: 10.1016/J.Bbi.2020.03.035  0.341
2020 Korgaonkar AA, Li Y, Sekhar D, Subramanian D, Guevarra J, Swietek B, Pallottie A, Singh S, Kella K, Elkabes S, Santhakumar V. TLR4 signaling in neurons enhances calcium-permeable AMPAR currents and drives post-traumatic epileptogenesis. Annals of Neurology. PMID 32031699 DOI: 10.1002/Ana.25698  0.379
2019 Chitturi J, Li Y, Santhakumar V, Kannurpatti SS. Consolidated Biochemical Profile of Subacute Stage Traumatic Brain Injury in Early Development. Frontiers in Neuroscience. 13: 431. PMID 31130841 DOI: 10.3389/Fnins.2019.00431  0.342
2018 Chitturi J, Li Y, Santhakumar V, Kannurpatti SS. Early behavioral and metabolomic change after mild to moderate traumatic brain injury in the developing brain. Neurochemistry International. 120: 75-86. PMID 30098378 DOI: 10.1016/J.Neuint.2018.08.003  0.32
2018 Parent M, Li Y, Santhakumar V, Hyder F, Sanganahalli BG, Kannurpatti S. Alterations of parenchymal microstructure, neuronal connectivity and cerebrovascular resistance at adolescence following mild to moderate traumatic brain injury in early development. Journal of Neurotrauma. PMID 29855211 DOI: 10.1089/Neu.2018.5741  0.36
2017 Neuberger EJ, Gupta A, Subramanian D, Korgaonkar AA, Santhakumar V. Converging early responses to brain injury pave the road to epileptogenesis. Journal of Neuroscience Research. PMID 29193309 DOI: 10.1002/Jnr.24202  0.703
2016 Swietek B, Gupta A, Proddutur A, Santhakumar V. Immunostaining of Biocytin-filled and Processed Sections for Neurochemical Markers. Journal of Visualized Experiments : Jove. PMID 28117774 DOI: 10.3791/54880  0.767
2016 Abdul-Muneer PM, Conte AA, Haldar D, Long M, Patel R, Santhakumar V, Overall CM, Pfister BJ. Traumatic brain injury induced matrix metalloproteinase2 cleaves CXCL12α (stromal cell derived factor 1α) and causes neurodegeneration. Brain, Behavior, and Immunity. PMID 27614125 DOI: 10.1016/J.Bbi.2016.09.002  0.341
2016 Abdul-Muneer PM, Long M, Conte AA, Santhakumar V, Pfister BJ. High Ca(2+) Influx During Traumatic Brain Injury Leads to Caspase-1-Dependent Neuroinflammation and Cell Death. Molecular Neurobiology. PMID 27289225 DOI: 10.1007/S12035-016-9949-4  0.344
2016 Murugan M, Santhakumar V, Kannurpatti SS. Facilitating Mitochondrial Calcium Uptake Improves Activation-Induced Cerebral Blood Flow and Behavior after mTBI. Frontiers in Systems Neuroscience. 10: 19. PMID 27013987 DOI: 10.3389/Fnsys.2016.00019  0.567
2016 Yu J, Swietek B, Proddutur A, Santhakumar V. Dentate cannabinoid-sensitive interneurons undergo unique and selective strengthening of mutual synaptic inhibition in experimental epilepsy. Neurobiology of Disease. PMID 26804027 DOI: 10.1016/J.Nbd.2016.01.013  0.812
2015 Proddutur A, Santhakumar V. Marching Towards a Seizure: Spatio-Temporal Evolution of Preictal Activity. Epilepsy Currents / American Epilepsy Society. 15: 267-8. PMID 26448732 DOI: 10.5698/1535-7511-15.5.267  0.749
2015 Yu J, Proddutur A, Swietek B, Elgammal FS, Santhakumar V. Functional Reduction in Cannabinoid-Sensitive Heterotypic Inhibition of Dentate Basket Cells in Epilepsy: Impact on Network Rhythms. Cerebral Cortex (New York, N.Y. : 1991). PMID 26400918 DOI: 10.1093/Cercor/Bhv199  0.814
2015 Yu J, Swietek B, Proddutur A, Santhakumar V. Dentate total molecular layer interneurons mediate cannabinoid-sensitive inhibition. Hippocampus. 25: 884-9. PMID 25603947 DOI: 10.1002/Hipo.22419  0.793
2015 Li Y, Korgaonkar AA, Swietek B, Wang J, Elgammal FS, Elkabes S, Santhakumar V. Toll-like receptor 4 enhancement of non-NMDA synaptic currents increases dentate excitability after brain injury. Neurobiology of Disease. 74: 240-53. PMID 25497689 DOI: 10.1016/J.Nbd.2014.11.021  0.406
2015 Pang KC, Sinha S, Avcu P, Roland JJ, Nadpara N, Pfister B, Long M, Santhakumar V, Servatius RJ. Long-lasting suppression of acoustic startle response after mild traumatic brain injury. Journal of Neurotrauma. 32: 801-10. PMID 25412226 DOI: 10.1089/Neu.2014.3451  0.312
2014 Ordek G, Proddutur A, Santhakumar V, Pfister BJ, Sahin M. Electrophysiological monitoring of injury progression in the rat cerebellar cortex. Frontiers in Systems Neuroscience. 8: 197. PMID 25346664 DOI: 10.3389/Fnsys.2014.00197  0.775
2014 Neuberger EJ, Abdul Wahab R, Jayakumar A, Pfister BJ, Santhakumar V. Distinct effect of impact rise times on immediate and early neuropathology after brain injury in juvenile rats. Journal of Neuroscience Research. 92: 1350-61. PMID 24799156 DOI: 10.1002/Jnr.23401  0.37
2013 Proddutur A, Yu J, Elgammal FS, Santhakumar V. Seizure-induced alterations in fast-spiking basket cell GABA currents modulate frequency and coherence of gamma oscillation in network simulations. Chaos (Woodbury, N.Y.). 23: 046109. PMID 24387588 DOI: 10.1063/1.4830138  0.806
2013 Santhakumar V, Meera P, Karakossian MH, Otis TS. A reinforcing circuit action of extrasynaptic GABAA receptor modulators on cerebellar granule cell inhibition. Plos One. 8: e72976. PMID 23977374 DOI: 10.1371/Journal.Pone.0072976  0.774
2013 Yu J, Proddutur A, Elgammal FS, Ito T, Santhakumar V. Status epilepticus enhances tonic GABA currents and depolarizes GABA reversal potential in dentate fast-spiking basket cells. Journal of Neurophysiology. 109: 1746-63. PMID 23324316 DOI: 10.1152/Jn.00891.2012  0.8
2012 Gupta A, Elgammal FS, Proddutur A, Shah S, Santhakumar V. Decrease in tonic inhibition contributes to increase in dentate semilunar granule cell excitability after brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 2523-37. PMID 22396425 DOI: 10.1523/Jneurosci.4141-11.2012  0.812
2010 Santhakumar V, Jones RT, Mody I. Developmental regulation and neuroprotective effects of striatal tonic GABAA currents. Neuroscience. 167: 644-55. PMID 20206233 DOI: 10.1016/J.Neuroscience.2010.02.048  0.745
2007 Morgan RJ, Santhakumar V, Soltesz I. Modeling the dentate gyrus. Progress in Brain Research. 163: 639-58. PMID 17765743 DOI: 10.1016/S0079-6123(07)63035-0  0.718
2007 Santhakumar V, Wallner M, Otis TS. Ethanol acts directly on extrasynaptic subtypes of GABAA receptors to increase tonic inhibition. Alcohol (Fayetteville, N.Y.). 41: 211-21. PMID 17591544 DOI: 10.1016/J.Alcohol.2007.04.011  0.745
2007 Dyhrfjeld-Johnsen J, Santhakumar V, Morgan RJ, Huerta R, Tsimring L, Soltesz I. Topological determinants of epileptogenesis in large-scale structural and functional models of the dentate gyrus derived from experimental data. Journal of Neurophysiology. 97: 1566-87. PMID 17093119 DOI: 10.1152/Jn.00950.2006  0.792
2006 Santhakumar V, Hanchar HJ, Wallner M, Olsen RW, Otis TS. Contributions of the GABAA receptor alpha6 subunit to phasic and tonic inhibition revealed by a naturally occurring polymorphism in the alpha6 gene. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3357-64. PMID 16554486 DOI: 10.1523/Jneurosci.4799-05.2006  0.769
2005 Santhakumar V, Aradi I, Soltesz I. Role of mossy fiber sprouting and mossy cell loss in hyperexcitability: a network model of the dentate gyrus incorporating cell types and axonal topography. Journal of Neurophysiology. 93: 437-53. PMID 15342722 DOI: 10.1152/Jn.00777.2004  0.695
2004 Santhakumar V, Soltesz I. Plasticity of interneuronal species diversity and parameter variance in neurological diseases. Trends in Neurosciences. 27: 504-10. PMID 15271499 DOI: 10.1016/J.Tins.2004.06.002  0.706
2004 Aradi I, Santhakumar V, Soltesz I. Impact of heterogeneous perisomatic IPSC populations on pyramidal cell firing rates. Journal of Neurophysiology. 91: 2849-58. PMID 15136604 DOI: 10.1152/Jn.00916.2003  0.716
2004 Ratzliff Ad, Howard AL, Santhakumar V, Osapay I, Soltesz I. Rapid deletion of mossy cells does not result in a hyperexcitable dentate gyrus: implications for epileptogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2259-69. PMID 14999076 DOI: 10.1523/Jneurosci.5191-03.2004  0.824
2003 Santhakumar V, Voipio J, Kaila K, Soltesz I. Post-traumatic hyperexcitability is not caused by impaired buffering of extracellular potassium. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5865-76. PMID 12843291 DOI: 10.1523/Jneurosci.23-13-05865.2003  0.673
2002 Chen K, Aradi I, Santhakumar V, Soltesz I. H-channels in epilepsy: new targets for seizure control? Trends in Pharmacological Sciences. 23: 552-7. PMID 12457772 DOI: 10.1016/S0165-6147(02)02110-7  0.649
2002 Aradi I, Santhakumar V, Chen K, Soltesz I. Postsynaptic effects of GABAergic synaptic diversity: regulation of neuronal excitability by changes in IPSC variance. Neuropharmacology. 43: 511-22. PMID 12367598 DOI: 10.1016/S0028-3908(02)00167-3  0.743
2002 Ratzliff Ad, Santhakumar V, Howard A, Soltesz I. Mossy cells in epilepsy: rigor mortis or vigor mortis? Trends in Neurosciences. 25: 140-4. PMID 11852145 DOI: 10.1016/S0166-2236(00)02122-6  0.801
2001 Santhakumar V, Ratzliff AD, Jeng J, Toth Z, Soltesz I. Long-term hyperexcitability in the hippocampus after experimental head trauma. Annals of Neurology. 50: 708-17. PMID 11761468 DOI: 10.1002/Ana.1230  0.8
2000 Santhakumar V, Bender R, Frotscher M, Ross ST, Hollrigel GS, Toth Z, Soltesz I. Granule cell hyperexcitability in the early post-traumatic rat dentate gyrus: the 'irritable mossy cell' hypothesis. The Journal of Physiology. 524: 117-34. PMID 10747187 DOI: 10.1111/J.1469-7793.2000.00117.X  0.784
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