| Year |
Citation |
Score |
| 2023 |
Delbeau M, Omollo EO, Froom R, Koh S, Mooney RA, Lilic M, Brewer JJ, Rock J, Darst SA, Campbell EA, Landick R. Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis. Molecular Cell. PMID 37116494 DOI: 10.1016/j.molcel.2023.04.007 |
0.673 |
|
| 2023 |
You L, Omollo EO, Yu C, Mooney RA, Shi J, Shen L, Wu X, Wen A, He D, Zeng Y, Feng Y, Landick R, Zhang Y. Structural basis for intrinsic transcription termination. Nature. PMID 36631609 DOI: 10.1038/s41586-022-05604-1 |
0.739 |
|
| 2021 |
Shiver AL, Osadnik H, Peters JM, Mooney RA, Wu PI, Henry KK, Braberg H, Krogan NJ, Hu JC, Landick R, Huang KC, Gross CA. Chemical-genetic interrogation of RNA polymerase mutants reveals structure-function relationships and physiological tradeoffs. Molecular Cell. 81: 2201-2215.e9. PMID 34019789 DOI: 10.1016/j.molcel.2021.04.027 |
0.73 |
|
| 2020 |
Lilic M, Chen J, Boyaci H, Braffman N, Hubin EA, Herrmann J, Müller R, Mooney R, Landick R, Darst SA, Campbell EA. The antibiotic sorangicin A inhibits promoter DNA unwinding in a rifampicin-resistant RNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. PMID 33199626 DOI: 10.1073/pnas.2013706117 |
0.625 |
|
| 2019 |
Stumper SK, Ravi H, Friedman LJ, Mooney RA, Corrêa IR, Gershenson A, Landick R, Gelles J. Delayed inhibition mechanism for secondary channel factor regulation of ribosomal RNA transcription. Elife. 8. PMID 30720429 DOI: 10.7554/Elife.40576 |
0.728 |
|
| 2019 |
Bellecourt MJ, Ray-Soni A, Harwig A, Mooney RA, Landick R. RNA Polymerase Clamp Movement Aids Dissociation from DNA but Is Not Required for RNA Release at Intrinsic Terminators. Journal of Molecular Biology. PMID 30630008 DOI: 10.1016/J.Jmb.2019.01.003 |
0.722 |
|
| 2019 |
Saba J, Chua XY, Mishanina TV, Nayak D, Windgassen TA, Mooney RA, Landick R. The elemental mechanism of transcriptional pausing. Elife. 8. PMID 30618376 DOI: 10.7554/Elife.40981 |
0.718 |
|
| 2019 |
Stumper SK, Ravi H, Friedman LJ, Mooney RA, Jnr IRC, Gershenson A, Landick R, Gelles J. Author response: Delayed inhibition mechanism for secondary channel factor regulation of ribosomal RNA transcription Elife. DOI: 10.7554/Elife.40576.Sa2 |
0.699 |
|
| 2018 |
Kang JY, Mooney RA, Nedialkov Y, Saba J, Mishanina TV, Artsimovitch I, Landick R, Darst SA. Structural Basis for Transcript Elongation Control by NusG Family Universal Regulators. Cell. PMID 29887376 DOI: 10.1016/J.Cell.2018.05.017 |
0.72 |
|
| 2018 |
Helmling C, Klötzner DP, Sochor F, Mooney RA, Wacker A, Landick R, Fürtig B, Heckel A, Schwalbe H. Life times of metastable states guide regulatory signaling in transcriptional riboswitches. Nature Communications. 9: 944. PMID 29507289 DOI: 10.1038/S41467-018-03375-W |
0.715 |
|
| 2018 |
Kang JY, Mishanina TV, Bellecourt MJ, Mooney RA, Darst SA, Landick R. RNA Polymerase Accommodates a Pause RNA Hairpin by Global Conformational Rearrangements that Prolong Pausing. Molecular Cell. 69: 802-815.e1. PMID 29499135 DOI: 10.1016/J.Molcel.2018.01.018 |
0.751 |
|
| 2018 |
Boyaci H, Chen J, Lilic M, Palka M, Mooney RA, Landick R, Darst SA, Campbell EA. Fidaxomicin jamsRNA polymerase motions needed for initiation via RbpA contacts. Elife. 7. PMID 29480804 DOI: 10.7554/eLife.34823 |
0.641 |
|
| 2018 |
Saba J, Chua XY, Mishanina TV, Nayak D, Windgassen TA, Mooney RA, Landick R. Author response: The elemental mechanism of transcriptional pausing Elife. DOI: 10.7554/Elife.40981.025 |
0.573 |
|
| 2018 |
Boyaci H, Chen J, Lilic M, Palka M, Mooney RA, Landick R, Darst SA, Campbell EA. Author response: Fidaxomicin jams Mycobacterium tuberculosis RNA polymerase motions needed for initiation via RbpA contacts Elife. DOI: 10.7554/Elife.34823.030 |
0.631 |
|
| 2018 |
Kang JY, Mooney RA, Artsimovitch I, Landick R, Darst SA. Molecular mechanism of transcription pause inhibition by elongation factor NusG and RfaH Cell. DOI: 10.2210/Pdb6C6T/Pdb |
0.608 |
|
| 2018 |
Boyaci H, Chen J, Lilic M, Palka M, Mooney RA, Landick R, Darst SA, Campbell EA. Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts. Elife. 7. DOI: 10.2210/Pdb6C04/Pdb |
0.645 |
|
| 2017 |
Ray-Soni A, Mooney RA, Landick R. Trigger loop dynamics can explain stimulation of intrinsic termination by bacterial RNA polymerase without terminator hairpin contact. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078293 DOI: 10.1073/Pnas.1706247114 |
0.715 |
|
| 2017 |
Mishanina TV, Palo MZ, Nayak D, Mooney RA, Landick R. Trigger loop of RNA polymerase is a positional, not acid-base, catalyst for both transcription and proofreading. Proceedings of the National Academy of Sciences of the United States of America. PMID 28607053 DOI: 10.1073/Pnas.1702383114 |
0.721 |
|
| 2017 |
Steinert H, Sochor F, Wacker A, Buck J, Helmling C, Hiller F, Keyhani S, Noeske J, Grimm SK, Rudolph MM, Keller H, Mooney RA, Landick R, Suess B, Fürtig B, et al. Pausing guides RNA folding to populate transiently stable RNA structures for riboswitch-based transcription regulation. Elife. 6. PMID 28541183 DOI: 10.7554/Elife.21297 |
0.715 |
|
| 2017 |
Kohler R, Mooney RA, Mills DJ, Landick R, Cramer P. Architecture of a transcribing-translating expressome. Science (New York, N.Y.). 356: 194-197. PMID 28408604 DOI: 10.1126/Science.Aal3059 |
0.733 |
|
| 2017 |
Tetone LE, Friedman LJ, Osborne ML, Ravi H, Kyzer S, Stumper SK, Mooney RA, Landick R, Gelles J. Dynamics of GreB-RNA polymerase interaction allow a proofreading accessory protein to patrol for transcription complexes needing rescue. Proceedings of the National Academy of Sciences of the United States of America. PMID 28137878 DOI: 10.1073/Pnas.1616525114 |
0.69 |
|
| 2017 |
Steinert H, Sochor F, Wacker A, Buck J, Helmling C, Hiller F, Keyhani S, Noeske J, Grimm S, Rudolph MM, Keller H, Mooney RA, Landick R, Suess B, Fürtig B, et al. Author response: Pausing guides RNA folding to populate transiently stable RNA structures for riboswitch-based transcription regulation Elife. DOI: 10.7554/Elife.21297.018 |
0.727 |
|
| 2015 |
Tetone LE, Friedman LJ, Osborne ML, Ravi H, Kyzer S, Mooney RA, Landick R, Gelles J. Dynamics of GreB Interactions with RNA Polymerase: How a Regulatory Protein may Patrol the Genome for Transcription Complexes to Rescue Biophysical Journal. 108: 507a-508a. DOI: 10.1016/J.Bpj.2014.11.2778 |
0.709 |
|
| 2014 |
Windgassen TA, Mooney RA, Nayak D, Palangat M, Zhang J, Landick R. Trigger-helix folding pathway and SI3 mediate catalysis and hairpin-stabilized pausing by Escherichia coli RNA polymerase. Nucleic Acids Research. 42: 12707-21. PMID 25336618 DOI: 10.1093/Nar/Gku997 |
0.741 |
|
| 2014 |
Hein PP, Kolb KE, Windgassen T, Bellecourt MJ, Darst SA, Mooney RA, Landick R. RNA polymerase pausing and nascent-RNA structure formation are linked through clamp-domain movement. Nature Structural & Molecular Biology. 21: 794-802. PMID 25108353 DOI: 10.1038/Nsmb.2867 |
0.819 |
|
| 2014 |
Larson MH, Mooney RA, Peters JM, Windgassen T, Nayak D, Gross CA, Block SM, Greenleaf WJ, Landick R, Weissman JS. A pause sequence enriched at translation start sites drives transcription dynamics in vivo. Science (New York, N.Y.). 344: 1042-7. PMID 24789973 DOI: 10.1126/Science.1251871 |
0.748 |
|
| 2014 |
Czyz A, Mooney RA, Iaconi A, Landick R. Mycobacterial RNA polymerase requires a U-tract at intrinsic terminators and is aided by NusG at suboptimal terminators. Mbio. 5: e00931. PMID 24713321 DOI: 10.1128/Mbio.00931-14 |
0.738 |
|
| 2014 |
Zhang Y, Mooney RA, Grass JA, Sivaramakrishnan P, Herman C, Landick R, Wang JD. DksA guards elongating RNA polymerase against ribosome-stalling-induced arrest. Molecular Cell. 53: 766-78. PMID 24606919 DOI: 10.1016/J.Molcel.2014.02.005 |
0.758 |
|
| 2013 |
Mooney RA, Landick R. Building a better stop sign: understanding the signals that terminate transcription. Nature Methods. 10: 618-9. PMID 23807194 DOI: 10.1038/Nmeth.2527 |
0.612 |
|
| 2013 |
Nayak D, Voss M, Windgassen T, Mooney RA, Landick R. Cys-pair reporters detect a constrained trigger loop in a paused RNA polymerase. Molecular Cell. 50: 882-93. PMID 23769674 DOI: 10.1016/J.Molcel.2013.05.015 |
0.74 |
|
| 2012 |
Peters JM, Mooney RA, Grass JA, Jessen ED, Tran F, Landick R. Rho and NusG suppress pervasive antisense transcription in Escherichia coli. Genes & Development. 26: 2621-33. PMID 23207917 DOI: 10.1101/Gad.196741.112 |
0.759 |
|
| 2012 |
Koslover DJ, Fazal FM, Mooney RA, Landick R, Block SM. Binding and translocation of termination factor rho studied at the single-molecule level. Journal of Molecular Biology. 423: 664-76. PMID 22885804 DOI: 10.1016/J.Jmb.2012.07.027 |
0.696 |
|
| 2012 |
Burmann BM, Knauer SH, Sevostyanova A, Schweimer K, Mooney RA, Landick R, Artsimovitch I, Rösch P. An α helix to β barrel domain switch transforms the transcription factor RfaH into a translation factor. Cell. 150: 291-303. PMID 22817892 DOI: 10.1016/J.Cell.2012.05.042 |
0.668 |
|
| 2011 |
Bratton BP, Mooney RA, Weisshaar JC. Spatial distribution and diffusive motion of RNA polymerase in live Escherichia coli. Journal of Bacteriology. 193: 5138-46. PMID 21784927 DOI: 10.1128/Jb.00198-11 |
0.363 |
|
| 2011 |
Sevostyanova A, Belogurov GA, Mooney RA, Landick R, Artsimovitch I. The β subunit gate loop is required for RNA polymerase modification by RfaH and NusG. Molecular Cell. 43: 253-62. PMID 21777814 DOI: 10.1016/J.Molcel.2011.05.026 |
0.731 |
|
| 2011 |
Davis SE, Mooney RA, Kanin EI, Grass J, Landick R, Ansari AZ. Mapping E. coli RNA polymerase and associated transcription factors and identifying promoters genome-wide. Methods in Enzymology. 498: 449-71. PMID 21601690 DOI: 10.1016/B978-0-12-385120-8.00020-6 |
0.661 |
|
| 2010 |
Cohen SE, Lewis CA, Mooney RA, Kohanski MA, Collins JJ, Landick R, Walker GC. Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 107: 15517-22. PMID 20696893 DOI: 10.1073/Pnas.1005203107 |
0.628 |
|
| 2010 |
Herbert KM, Zhou J, Mooney RA, Porta AL, Landick R, Block SM. E. coli NusG inhibits backtracking and accelerates pause-free transcription by promoting forward translocation of RNA polymerase. Journal of Molecular Biology. 399: 17-30. PMID 20381500 DOI: 10.1016/J.Jmb.2010.03.051 |
0.704 |
|
| 2009 |
Peters JM, Mooney RA, Kuan PF, Rowland JL, Keles S, Landick R. Rho directs widespread termination of intragenic and stable RNA transcription. Proceedings of the National Academy of Sciences of the United States of America. 106: 15406-11. PMID 19706412 DOI: 10.1073/Pnas.0903846106 |
0.801 |
|
| 2009 |
Mooney RA, Schweimer K, Rösch P, Gottesman M, Landick R. Two structurally independent domains of E. coli NusG create regulatory plasticity via distinct interactions with RNA polymerase and regulators. Journal of Molecular Biology. 391: 341-58. PMID 19500594 DOI: 10.1016/J.Jmb.2009.05.078 |
0.726 |
|
| 2009 |
Mooney RA, Davis SE, Peters JM, Rowland JL, Ansari AZ, Landick R. Regulator trafficking on bacterial transcription units in vivo. Molecular Cell. 33: 97-108. PMID 19150431 DOI: 10.1016/J.Molcel.2008.12.021 |
0.751 |
|
| 2009 |
Belogurov GA, Mooney RA, Svetlov V, Landick R, Artsimovitch I. Functional specialization of transcription elongation factors. The Embo Journal. 28: 112-22. PMID 19096362 DOI: 10.1038/Emboj.2008.268 |
0.708 |
|
| 2008 |
Westblade LF, Minakhin L, Kuznedelov K, Tackett AJ, Chang EJ, Mooney RA, Vvedenskaya I, Wang QJ, Fenyö D, Rout MP, Landick R, Chait BT, Severinov K, Darst SA. Rapid isolation and identification of bacteriophage T4-encoded modifications of Escherichia coli RNA polymerase: a generic method to study bacteriophage/host interactions. Journal of Proteome Research. 7: 1244-50. PMID 18271525 DOI: 10.1021/Pr070451J |
0.675 |
|
| 2006 |
Herbert KM, La Porta A, Wong BJ, Mooney RA, Neuman KC, Landick R, Block SM. Sequence-resolved detection of pausing by single RNA polymerase molecules. Cell. 125: 1083-94. PMID 16777599 DOI: 10.1016/J.Cell.2006.04.032 |
0.664 |
|
| 2006 |
Ederth J, Mooney RA, Isaksson LA, Landick R. Functional interplay between the jaw domain of bacterial RNA polymerase and allele-specific residues in the product RNA-binding pocket. Journal of Molecular Biology. 356: 1163-79. PMID 16405998 DOI: 10.1016/J.Jmb.2005.11.080 |
0.746 |
|
| 2005 |
Mooney RA, Darst SA, Landick R. Sigma and RNA polymerase: an on-again, off-again relationship? Molecular Cell. 20: 335-45. PMID 16285916 DOI: 10.1016/J.Molcel.2005.10.015 |
0.744 |
|
| 2004 |
Geszvain K, Gruber TM, Mooney RA, Gross CA, Landick R. A hydrophobic patch on the flap-tip helix of E.coli RNA polymerase mediates sigma(70) region 4 function. Journal of Molecular Biology. 343: 569-87. PMID 15465046 DOI: 10.1016/J.Jmb.2004.08.063 |
0.786 |
|
| 2003 |
Mooney RA, Landick R. Tethering sigma70 to RNA polymerase reveals high in vivo activity of sigma factors and sigma70-dependent pausing at promoter-distal locations. Genes & Development. 17: 2839-51. PMID 14630944 DOI: 10.1101/Gad.1142203 |
0.716 |
|
| 2003 |
Santangelo TJ, Mooney RA, Landick R, Roberts JW. RNA polymerase mutations that impair conversion to a termination-resistant complex by Q antiterminator proteins. Genes & Development. 17: 1281-92. PMID 12756229 DOI: 10.1101/Gad.1082103 |
0.707 |
|
| 2002 |
Yuzenkova J, Delgado M, Nechaev S, Savalia D, Epshtein V, Artsimovitch I, Mooney RA, Landick R, Farias RN, Salomon R, Severinov K. Mutations of bacterial RNA polymerase leading to resistance to microcin j25. The Journal of Biological Chemistry. 277: 50867-75. PMID 12401787 DOI: 10.1074/Jbc.M209425200 |
0.595 |
|
| 2000 |
Opalka N, Mooney RA, Richter C, Severinov K, Landick R, Darst SA. Direct localization of a beta-subunit domain on the three-dimensional structure of Escherichia coli RNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. 97: 617-22. PMID 10639128 DOI: 10.1073/Pnas.97.2.617 |
0.627 |
|
| 1999 |
Mooney RA, Landick R. RNA polymerase unveiled. Cell. 98: 687-90. PMID 10499791 DOI: 10.1016/S0092-8674(00)81483-X |
0.685 |
|
| 1998 |
Mooney RA, Artsimovitch I, Landick R. Information processing by RNA polymerase: recognition of regulatory signals during RNA chain elongation. Journal of Bacteriology. 180: 3265-75. PMID 9642176 DOI: 10.1128/Jb.180.13.3265-3275.1998 |
0.711 |
|
| 1997 |
Severinov K, Mooney R, Darst SA, Landick R. Tethering of the large subunits of Escherichia coli RNA polymerase. The Journal of Biological Chemistry. 272: 24137-40. PMID 9305860 DOI: 10.1074/Jbc.272.39.24137 |
0.667 |
|
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